Centrifugally Extracting Patents (Class 210/781)
  • Patent number: 11103883
    Abstract: Provided is a centrifuge including: a rotary chamber configured to rotate so that centrifugal force acts on a substance contained in the rotary chamber; a storage unit configured to store a certain component separated from the substance in the rotary chamber by the centrifugal force according to rotation of the rotary chamber; and a filter located between the storage unit and the rotary chamber and through which the certain component, which is separated from the substance in the rotary chamber by the centrifugal force according to the rotation of the rotary chamber, passes to be stored in the storage unit. The storage unit includes a return prevention unit configured to prevent the certain component, which is separated from the substance in the rotary chamber by the centrifugal force according to the rotation of the rotary chamber and is stored in the storage unit, from returning from the storage unit to the rotary chamber.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: August 31, 2021
    Assignee: MEDIKAN CO., LTD.
    Inventors: Hee Young Lee, Hyun Jin Yang, Dae Chang Bae
  • Patent number: 10214764
    Abstract: The present invention is directed to a separation device or container that can be used in the separation, isolation or pelleting of microorganisms from a test samples known to contain or suspected of containing said microorganisms. Subsequently, the separated, isolated or pelleted microorganism sample can undergo one or more interrogation steps to provide measurements useful for the characterization and/or identification of microorganism. In one aspect of the present invention, the interrogation steps can occur in situ in the separation device or container described herein.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: February 26, 2019
    Assignee: BIOMERIEUX, INC.
    Inventors: John Walsh, Jones M. Hyman, Christopher Ronsick, John Link, Ron Robinson, Mark Wilson
  • Patent number: 10179841
    Abstract: The Present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s).
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: January 15, 2019
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Alexander A. Green, Mark C. Hersam
  • Patent number: 9808568
    Abstract: A system for separating and concentrating a component of a whole material is disclosed. The whole material can include a material that has more than one component, such as whole blood that can include at least red blood cells, monocytes, and plasma. The system can include a substantially single container including a separation section and a concentration section wherein a component can be moved from the separation section, after a separation, to the concentration section to be concentrated. The concentrated component can then be withdrawn from the separation and concentration container for a selected procedure.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: November 7, 2017
    Assignee: Biomet Biologics, LLC
    Inventor: Patrick S. O'Connell, Jr.
  • Patent number: 9442108
    Abstract: In a centrifugal microfluidic device for conducting capture assays, a microfluidic platform rotates in a plane of rotation and has at least one capture surface for immobilizing a target particle of interest in the device. The capture surface oriented so that it is not parallel to the plane of rotation of the device and is positionally fixed in the device during operation of the device. The centrifugal force arising from rotation of the device forces the target particles against the capture surface. Capture efficiency is independent of the rate of flow of the fluid and independent of the rate of rotation of the microfluidic platform.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: September 13, 2016
    Assignee: National Research Council of Canada
    Inventors: Liviu Clime, Xuyen Dai Hoa, Teodor Veres, Francois Normandin
  • Patent number: 9360408
    Abstract: The invention includes a method of determining the effective density of nanomaterial agglomerates in liquids, such as but not limited to physiological fluids, using volumetric centrifugation. The method of the invention allows for the development of reliable and efficient in vitro dosimetry and methods for toxicological testing of engineered nanomaterials.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: June 7, 2016
    Assignee: President and Fellows of Harvard College
    Inventors: Philip Demokritou, Glen Deloid, Joel Cohen
  • Patent number: 8999176
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: April 7, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
  • Publication number: 20150083672
    Abstract: A processing system for processing raw slurry material has a barrel member, at least one transport member, and at least one separator member. The barrel member defines a processing chamber and at least one intermediate opening. The processing chamber defines a pre-processing portion and a separator portion. The at least one transport member is arranged within the pre-processing portion of the processing chamber. The at least one separator member is arranged within the separator portion of the processing chamber and configured to define at least one separator gap. As the barrel member rotates about a longitudinal axis thereof, the at least one transport member transports at least a portion of the raw slurry material through the pre-processing portion of the processing chamber, and the at least one separator member transports at least a portion of the raw slurry material through the separator portion of the processing chamber.
    Type: Application
    Filed: November 17, 2014
    Publication date: March 26, 2015
    Inventor: David DeWaard
  • Patent number: 8980107
    Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: March 17, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Micheal J. Domanico, James P. Light, II, Keith Koptizke, John Zeis
  • Patent number: 8961445
    Abstract: This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: February 24, 2015
    Assignee: Biomet Biologics, LLC
    Inventors: Douglas M. Arm, Michael Ponticiello, Surinder Mathur, Andrew G. Hood
  • Patent number: 8951417
    Abstract: A method of transporting magnetic particles enables magnetic particles to be transported between a plurality of microfluidic chambers which are connected to one another via a fluidic connection on a radially inner side, and are fluidically separated from one another on a radially outer side. Magnetic forces and centrifugal forces are exploited to transport magnetic particles from one chamber to another across phase boundaries.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: February 10, 2015
    Assignee: Hahn-Schickard-Gesellschaft fuer angewandte Forschung e.V
    Inventors: Oliver Strohmeier, Felix Von Stetten, Daniel Mark
  • Patent number: 8936162
    Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The tube and barrier maintain stability of one or more analyte levels, including potassium and glucose, within 10% of their initial values before centrifugation for at least four days.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: January 20, 2015
    Assignee: The Regents of the University of California
    Inventor: Jane Emerson
  • Patent number: 8926487
    Abstract: A syringe piston used in fat transplantation is structured such that free oil is easily separated from suctioned fat by a syringe piston having a filter and naturally discharged through the rear side thereof. The syringe piston without a shaft, used in fat transplantation, disposed in a syringe-shaped cylindrical vessel, includes a piston body without the shaft, a packing coupled with an outer surface of the piston body to seal between the piston body and the syringe-shaped cylindrical vessel, a free oil discharging hole communicated with the front side and the rear side of the piston body, an opening and closing device for opening and closing the free oil discharging hole, and a filtering device disposed in a passage through which free oil is discharged to filter fat and pass the free oil.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: January 6, 2015
    Inventor: Hee Young Lee
  • Patent number: 8911634
    Abstract: A device for separating materials of different densities is provided. A cup body has an internal cavity configured to hold media. An inner wall defines a central body region having an upper and lower end. The upper end is wider than the lower end. An interior shoulder circumscribes the upper end of the central body region. The interior shoulder defines a neck region above the central body region and a shoulder trap below the neck region. The shoulder trap circumscribes the upper end of the central body region and is wider than the neck region. When the device is spun about a central axis, the media travels upward along the inner wall toward the shoulder trap. Relatively more dense material in the media is collected in the shoulder trap, and relatively less dense material is expelled from the device through an opening above the neck region.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: December 16, 2014
    Assignee: Molecular Devices, LLC
    Inventors: Windsor Owens, Andrew Peterson, Yuri Osipchuk, Edward Verdonk
  • Patent number: 8906317
    Abstract: A production apparatus of composite silver nanoparticle including: a device for arranging a silver salt microparticle and at least an alcohol solvent selected from alcohols having a carbon number of 1 to 12; a raw material mixer for preparing an alcohol solution by mixing the silver salt microparticle into the alcohol solvent added more excessively than the mol number of the silver salt microparticle to make an excess alcohol solution; a reactor for generating a composite silver nanoparticle by heating the excess alcohol solution at a generation temperature PT generating an aldehyde for a generation time with a heater, in which a silver core is formed by reducing the silver salt microparticle by the alcohol solvent and/or the aldehyde and the composite silver nanoparticle having an organic coating layer originated from the alcohol solvent around the silver core is formed, and a chiller for cooling the alcohol solution.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: December 9, 2014
    Assignee: Applied Nanoparticle Laboratory Corporation
    Inventor: Teruo Komatsu
  • Publication number: 20140356446
    Abstract: An apparatus may allow separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Inventors: Michael D. LEACH, Joel C. HIGGINS, Matthew SWIFT, Nathan GORDON
  • Patent number: 8871100
    Abstract: Processing of a bulk liquid including particles, including use of a rotating strainer surface with openings disposed on a circumference thereof, the openings allowing an extracted liquid in the bulk liquid to pass through the strainer surface while preventing particles from passing through the strainer surface, such that a concentration of particles in the extracted liquid is less than in the bulk liquid; an extracted liquid outflow port which outputs the extracted liquid from an interior region of the rotating strainer surface; and a motor configured to rotate the strainer surface at a speed sufficient to generate a centrifugal force or turbulence at the openings sufficient to prevent the particles from clogging the openings, wherein the strainer surface is rotated and the extracted liquid is output through the extracted liquid outflow port when the strainer surface is fully submerged in the bulk liquid.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: October 28, 2014
    Assignee: SPX APV Denmark A/S
    Inventors: Michael Franklin Jørgensen, Klaus Pedersen
  • Patent number: 8852444
    Abstract: The present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s).
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: October 7, 2014
    Assignee: Northwestern University
    Inventors: Alexander A. Green, Mark C. Hersam
  • Patent number: 8790519
    Abstract: A method of extracting or removing a liquid phase from a whole sample using a centrifugal force is disclosed. Centrifugal forces are used to apply pressure to a whole sample and drive a liquid phase through a passage region that can be perforated and/or porous and maintain a drier portion within a separate container. The whole sample can be drier, which includes a remaining sample where excess or a selected amount of liquid is removed. Direct access to the separate container or area can then be made to provide for an efficient withdrawal of the drier material from the separation container.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: July 29, 2014
    Assignee: Biomet Biologics, LLC
    Inventors: Michael D. Leach, Jason Chavarria
  • Publication number: 20140197116
    Abstract: Fluid filtration devices, systems and methods are disclosed. The device comprises a pump-filter hybrid system that uses rotational motion to produce pressure to drive liquid through filter elements, capturing filtrate in an isolated chamber of the device and rejecting separated solids into a second isolated chamber. The fluid filtration device, which can be configured to filter a wide variety of fluids, comprises: an influent input manifold; an impeller bowl and filter assembly configured to rotate about an axis; a barrier and muting configuration to catch and distribute filtrate; a barrier and routing configuration to catch and distribute rejected solids.
    Type: Application
    Filed: January 11, 2013
    Publication date: July 17, 2014
    Inventor: Richard Frank Yanda
  • Patent number: 8778191
    Abstract: The invention concerns a centrifugal filtering device for filtering a fluid. The device comprises a rotatable inner casing forming an inner space and a rotatable outer casing forming an outer space. The device further comprises a fluid inlet, at least one filter and drive means. The drive means is configured to rotate the inner casing to create a centrifugal pressure. The pressure forces a part of the fluid contained in the inner space through the filter and to a radially outer position of the outer space. The filtered fluid forms a filtrate, the filtrate having a kinetic energy. The outer casing is configured to transport the filtrate from the radially outer position to a radially inner position of the outer space, permitting transfer of the kinetic energy from the filtrate to the outer casing, thereby permitting regaining of mechanical energy.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: July 15, 2014
    Assignee: Aqua Mundus AB
    Inventor: Fredrick Marelius
  • Patent number: 8696905
    Abstract: A concentrator is used for concentrating a fluid, particularly a plasma component out of blood, for treatment of a patient. The concentrator apparatus includes a main housing defining a centrifuge chamber, that also holds the filter. The concentrator allows viewing of the fluid after centrifuging, with an outlet port positionable at a height corresponding to the level of the fraction of the fluid to be further concentrated. Once the fluid is centrifuged, a portion of the fluid is drawn through the outlet, and then pressured past the filter to further concentrate the fluid using the same vessel as used for centrifuging. The same plunger is preferably used to draw centrifuged fluid from the centrifuge chamber as to pressure the centrifuged fluid past the filter.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: April 15, 2014
    Assignee: Circle Biologics, Inc.
    Inventors: Thomas Coull, Matthew R. Kyle, Louis S. Kidder
  • Publication number: 20140021147
    Abstract: Extracting or removing at least a portion of liquid phase from a whole sample using a centrifugal force is disclosed. Centrifugal forces are used to apply pressure to a whole sample and drive a liquid phase through a passage region that can be perforated and/or porous and maintain a drier portion within a separation container. The whole sample can be dried, which includes a remaining sample where excess or a selected amount of liquid is removed. Direct access to the separation container or area can then be made to provide for an efficient withdrawal of the drier material from the separation container.
    Type: Application
    Filed: September 23, 2013
    Publication date: January 23, 2014
    Applicant: Biomet Biologics, LLC
    Inventors: Michael D. LEACH, Jason Chavarria
  • Patent number: 8580183
    Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The barrier rapidly hardens forming a solid barrier when triggered by a suitable energy source.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: November 12, 2013
    Assignee: The Regents of the University of California
    Inventor: Jane F. Emerson
  • Patent number: 8568597
    Abstract: A process is disclosed for purification of silicon source material including trichlorosilane. First, the silicon source material in liquid state with impurities vapor and the other chlorosilane or silane are passing a first high gravity rotating packed bed with porous metal, at a temperature lower than the boiling point of the silicon source material, the impurities vapor and the other chlorosilane or silane are separated from the liquid silicon source material; second, the silicon source material in liquid state is fed to a second high gravity rotating packed bed, oxygen is also fed to the second high gravity rotating packed bed to form impurity-containing siloxane complexes with higher boiling point. Finally distilling to remove the impurity-containing siloxane complexes from the silicon source material.
    Type: Grant
    Filed: May 10, 2010
    Date of Patent: October 29, 2013
    Inventors: Shyang Su, Yi-Heng Su, Michael Vukelic
  • Publication number: 20130277320
    Abstract: A process for separating a first mother liquor stream is provided. The process comprises: separating a first mother liquor stream in a second solid liquid separation zone to produce a secondary wet cake stream and a second mother liquor stream; wherein the first mother liquor stream comprises water non-dispersible microfiber, water, and water dispersible sulfopolyester; wherein the second mother liquor stream comprises water and water dispersible sulfopolyester; and wherein the secondary wet cake stream comprises water non-dispersible polymer microfiber.
    Type: Application
    Filed: November 28, 2012
    Publication date: October 24, 2013
    Inventors: Kenny Randolph Parker, Daniel William Klosiewicz, Ramesh Chand Munjal, David J. Rogers, JR., Dustin A. Tremaine
  • Patent number: 8562840
    Abstract: A spin column device, which contains a rigid porous filter that retains its shape during centrifugation, chromatography methods using the device to isolate a desired substance, e.g., a biological molecule, from other substances in a mixture, and kits containing the device with one or more reagents for use in the method.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: October 22, 2013
    Assignee: Bioventures, Inc.
    Inventor: Elliott P. Dawson
  • Patent number: 8546026
    Abstract: Disclosed are a gas-liquid separator, a hydrogen generating apparatus, and a fuel cell generation system, having the same. The gas-liquid separator can include an inflow path, into which a fluid material having a liquid and a gas flows; a centrifugal path, connected to the inflow path to receive the fluid material and formed spirally such that the fluid material is separated into the liquid and the gas by difference in centrifugal forces, an outer side of the centrifugal path having stronger affinity for the liquid than an inner side of the centrifugal path; and an outflow path, connected to the centrifugal path and discharging the liquid and the gas, which have been separated in the centrifugal path. With the present invention, it is possible to efficiently separate gas such as hydrogen and liquid such as a electrolyte solution without complex devices.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: October 1, 2013
    Assignee: Samsung Electro-Mechanics Co., Ltd.
    Inventors: Eon-Soo Lee, Jae-Hyuk Jang, Hye-Yeon Cha
  • Patent number: 8480606
    Abstract: A system is disclosed for removing gas bubbles from blood during circulatory assist procedures. Such bubbles are generated, along with particulate matter, in an extracorporeal circulatory bypass system by the pump, oxygenator and other components. Current filters are inefficient at removing small bubbles that can cause neurological defects and renal and other organ failures in the patient. An active filter apparatus and method is disclosed that forces the bubbles to the center of the system where they are removed from the blood before the blood exits the filter. The filter comprises an axially elongate cylindrical shell with a blood inlet, a blood outlet and a gas outlet. A motor driven impeller spins the blood within the shell and forces the gas toward the center by centripetal force, utilizing the buoyancy effects of the bubbles in blood, whereby the bubbles can be bled off at the center of the filter.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: July 9, 2013
    Assignee: Indian Wells Medical, Inc.
    Inventors: David W. Wieting, Jay A. Lenker
  • Patent number: 8469202
    Abstract: A centrifugal processing bag, system and method for separating the components of a mixed material is presented. The processing bag includes a hub and a first port for receiving the mixed material, where the first port includes an outlet positioned within the processing bag at a perimeter of the bag. The processing bag also including a second port having a second port inlet spaced proximate the hub and away from a central axis of the hub. The second port directs a separated material collected from the second port inlet out of the processing bag.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: June 25, 2013
    Assignee: Velico Medical, Inc.
    Inventor: Keith M. Rosiello
  • Patent number: 8361005
    Abstract: This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: January 29, 2013
    Assignee: Biomet Biologics, LLC
    Inventors: Douglas M. Arm, Michael Ponticiello, Surinder Mathur, Andrew G. Hood
  • Patent number: 8318077
    Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The barrier rapidly hardens forming a solid barrier when triggered by a suitable energy source.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: November 27, 2012
    Assignee: The Regents of the University of California
    Inventor: Jane Emerson
  • Patent number: 8317034
    Abstract: The present invention relates to separating one or more of sand and other particulate matter from a mixture of animal waste and water. The present invention can help to control the discharge of noxious odors while processing material containing animal waste. An exemplary apparatus in accordance with the present invention includes a cylindrical housing and a non-rotating collection table. An exemplary apparatus in accordance with the present invention includes optional shield provided inside the cylindrical housing that can help to capture the particulate matter and that can also help to reduce the discharge of noxious gas and odors from the apparatus.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: November 27, 2012
    Inventor: John Patrick Fetrow
  • Patent number: 8318507
    Abstract: A method for the separation of particles of different densities using a step-wise gradient density extraction method as described herein where a sample is suspended in a liquid volume of an extracting medium of specific density and the particles that have a density less than or equal to that of the extracting medium of specific density can be recovered from a horizonatally rotatable hollow disk or a removable receptacle within a horizontally rotatable hollow disk designed for such purposes while the particles that have a density greater than the extracting medium of specific density form a deposit which can be cycled through the extraction process in an iterative fashion by varying the density of the extracting medium allowing the recovery of discrete particles of differing densities from a test sample.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: November 27, 2012
    Inventors: Marcus Joseph Horn, Wenkui Lan
  • Publication number: 20120285900
    Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Michael J. Domanico, James P. Light, II, Keith Koptizke, John Zeis
  • Patent number: 8282540
    Abstract: Methods for using a centrifuge are presented. A vessel containing a sample and a separator substance is placed within a centrifuge. Upon sufficient centrifugation, the sample separates into two or more fractions separated by the separator substance. The centrifuge exposes the separator substance to a sufficient energy to polymerize the separator substance to produce a hardened barrier between the fractions.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: October 9, 2012
    Assignee: The Regents of the University of California
    Inventor: Jane Emerson
  • Patent number: 8278118
    Abstract: A method for the separation of particles of different densities using a step-wise gradient density extraction method as described herein where a sample is suspended in a liquid volume of an extracting medium of specific density and the particles that have a density less than or equal to that of the extracting medium of specific density can be recovered from a horizonatally rotatable hollow disk or a removable receptacle within a horizontally rotatable hollow disk designed for such purposes while the particles that have a density greater than the extracting medium of specific density form a deposit which can be cycled through the extraction process in an iterative fashion by varying the density of the extracting medium allowing the recovery of discrete particles of differing densities from a test sample.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: October 2, 2012
    Assignee: Prospect Biosystems, Inc.
    Inventors: Marcus Joseph Horn, Wenkui Lan
  • Patent number: 8246842
    Abstract: A centrifuge (2) for separating solids from liquid of a slurry with a conveyor (12) having a hub (14) rotatable about an axis (34) and at a helical blade (16) extending axially and radially from the hub. A bowl (4) including a cylindrical section (6) extending from an upstream end of the conveyor and a conically diverging screen section (10) extending to a downstream end of the conveyor extends about the conveyor and is rotatable about the axis. The conically diverging screen section includes an angle (40) that reduces the coefficient of friction of the solids to allow a cake formed of the solids to slide in a controlled manner forward on the conically diverging screen section with minimal back pressure, but without allowing the solid cake to break loose from the conically diverging screen section and slide out of the centrifuge in an uncontrolled manner.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: August 21, 2012
    Assignee: Andritz Separation, Inc.
    Inventor: Nicholas Robert Frohlich, Jr.
  • Publication number: 20120193306
    Abstract: A system and method for filtering solvent including a housing for receiving the solvent and a filtering media, where the solvent is moved through the filtering media without using a pump.
    Type: Application
    Filed: January 24, 2012
    Publication date: August 2, 2012
    Inventors: Ronald S. Hood, Melvin W. Hughes
  • Patent number: 8192634
    Abstract: The separator screen arrangement of a centrifugal basket assembly reduces separator screen wear and eases structural replacement of worn parts. The centrifugal basket assembly comprises a screen-supporting basket; a separator screen, and a series of J-shaped dam segments. The separator screen is received and supported by the basket and comprises and inlet and a circular outlet end. The dam segments each comprise a dam portion, and a rim seat portion. The rim seat portions seat upon the rim, being attached thereto in a circular manner side-by-side such that the dam portions extend toward the inlet end. The dam portions dam material directed thereagainst from the inlet end so as to uniformly spread and layer material upon the separator screen before the material exits the basket assembly. The uniformly spread and layered material reduces wear of the separator screen. Material-drying and screen-protecting methodology is further supported by the basket assembly.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: June 5, 2012
    Inventor: Stephen R. Gilles
  • Patent number: 8187475
    Abstract: A device for isolating a component of a multi-component composition. The device includes a housing, a chamber, and a withdrawal port. The chamber is rotatably mounted within the housing. The chamber includes a chamber base and a sidewall. The side wall extends from the chamber base. At least a portion of the sidewall is defined by a filter that permits passage of a first component of the multi-component composition out of the chamber through the filter and to the housing base. The filter restricts passage of a second component of the multi-component composition through the filter. The withdrawal port extends from a position proximate to the housing base to an exterior of the device. The withdrawal port permits the withdrawal of the first component from the housing base to an exterior of the device.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: May 29, 2012
    Assignee: Biomet Biologics, LLC
    Inventors: Barry F. Hecker, Michael D. Leach
  • Patent number: 8153014
    Abstract: A mixture of single-walled carbon nanotubes (“SWNTs”) is separated into fractions of enriched chirality by preparing an aqueous suspension of a mixture of SWNTs and a surfactant, injecting a portion of the suspension on a column of separation medium having a density gradient, and centrifuging the column. In some embodiments, salt is added prior to centrifugation. In other embodiments, the centrifugation is performed at a temperature below room temperature. Fractions separate as colored bands in the column. The diameter of the separated SWNTs decreases with increasing density along the gradient of the column. The colored bands can be withdrawn separately from the column.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: April 10, 2012
    Assignee: Los Alamos National Security, LLC
    Inventors: Stephen K. Doorn, Sandip Niyogi
  • Patent number: 8151996
    Abstract: Contemplated whole blood separators tubes include a curable composition with a density intermediate to the density of serum and the cell-containing fraction. After centrifugation, the curable composition is located between the serum and the cell-containing fraction and preferably irradiated with UV light to initiate a curing reaction in which the curable composition solidifies to a barrier that is immobilized and resistant to breakdown at freezing temperatures and extended storage.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: April 10, 2012
    Assignee: The Regents of the University of California
    Inventor: Jane Emerson
  • Patent number: 8147845
    Abstract: Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: April 3, 2012
    Assignee: Oncolytics Biotech Inc.
    Inventors: Donald Morris, Bradley G. Thompson, Matthew C. Coffey
  • Patent number: 8128731
    Abstract: A method for separating and enriching isotopes in an efficient and low-cost manner from a condensation-system (liquid or/and solid) material including two or more different isotopes by taking advantage of the sedimentation of atoms through an acceleration field by ultra-high speed rotation. The condensation-system material is placed in a sedimentation tank which is then housed in a supercentrifuge. The supercentrifuge in its rotor is rotation driven by an ultra-high speed rotation power source, and an acceleration field of energy of 100000 G to 1500000 G, i.e., about 100 to 800 m/s in terms of peripheral velocity, is applied to the above condensed (liquid or/and solid) material under such a temperature that is specified by an isotope material to be enriched. In this case, a difference in centrifugal force applied is provided between the isotopes in the condensed (liquid or/and solid) material comprising the at least two isotopes.
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: March 6, 2012
    Assignees: National University Corporation Kumamoto University, Maruwa Electronic Inc.
    Inventors: Tsutomu Mashimo, Masao Ono, Xinsheng Huang, Yusuke Iguchi, Satoru Okayasu, Hiroshi Yasuoka, Koji Shibasaki, Masanori Sueyoshi
  • Patent number: 8123713
    Abstract: Method and apparatus for separating plasma from blood in a separation vessel and further separator the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the separation vessel to receive the separated plasma.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: February 28, 2012
    Assignee: Caridian BCT, Inc.
    Inventors: Thomas J. Felt, Frank Corbin, III, Steven Gage Urdahl
  • Patent number: 8119013
    Abstract: A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density that is configured to reach an equilibrium position in a suspension. The guide surface is carried on the buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: February 21, 2012
    Assignees: Hanuman, LLC, Biomet Biologics, LLC
    Inventors: Michael D. Leach, Randel Dorian, Jacy C. Hoeppner
  • Patent number: 8096422
    Abstract: Disclosed is a separator-concentrator, such as for separating and concentrating platelet-rich-plasma (PRP) from whole blood that is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly and a concentrator assembly. The centrifugal separation assembly comprises a centrifugal drum separator and a motor having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: January 17, 2012
    Assignees: Hanuman LLC, Biomet Biologics, LLC
    Inventors: Randel Dorian, Michael D. Leach
  • Publication number: 20110309037
    Abstract: A syringe piston used in fat transplantation is structured such that free oil is easily separated from suctioned fat by a syringe piston having a filter and naturally discharged through the rear side thereof. The syringe piston without a shaft, used in fat transplantation, disposed in a syringe-shaped cylindrical vessel, includes a piston body without the shaft, a packing coupled with an outer surface of the piston body to seal between the piston body and the syringe-shaped cylindrical vessel, a free oil discharging hole communicated with the front side and the rear side of the piston body, an opening and closing device for opening and closing the free oil discharging hole, and a filtering device disposed in a passage through which free oil is discharged to filter fat and pass the free oil.
    Type: Application
    Filed: September 20, 2010
    Publication date: December 22, 2011
    Inventor: Hee Young LEE
  • Patent number: 8070965
    Abstract: Separating a multi-phase mixture influent even during excessive flows of specific phases. The dynamic phase separator includes a chamber divided into two regions by an inner wall disposed radially inward relative to an outer wall. A gross separation region is defined between the inner wall and the outer wall, while a fine separation region lies inside an area defined by the inner wall and top of the chamber. Influent to be separated is fed through an inlet into the gross separation region. A plurality of porous disks are mounted to a rotatable shaft and disposed in the fine separation region. The outer and inner walls are separated by a predetermined distance sufficient to allow for adequate rotational velocity of incoming tangential flow of the influent and dwell time sufficient for natural separation of lighter phases from heavier phases within the gross separation region.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: December 6, 2011
    Inventor: Robert J. Tarves, Jr.