Abstract: Provided is a centrifuge including: a rotary chamber configured to rotate so that centrifugal force acts on a substance contained in the rotary chamber; a storage unit configured to store a certain component separated from the substance in the rotary chamber by the centrifugal force according to rotation of the rotary chamber; and a filter located between the storage unit and the rotary chamber and through which the certain component, which is separated from the substance in the rotary chamber by the centrifugal force according to the rotation of the rotary chamber, passes to be stored in the storage unit. The storage unit includes a return prevention unit configured to prevent the certain component, which is separated from the substance in the rotary chamber by the centrifugal force according to the rotation of the rotary chamber and is stored in the storage unit, from returning from the storage unit to the rotary chamber.

Abstract: The present invention is directed to a separation device or container that can be used in the separation, isolation or pelleting of microorganisms from a test samples known to contain or suspected of containing said microorganisms. Subsequently, the separated, isolated or pelleted microorganism sample can undergo one or more interrogation steps to provide measurements useful for the characterization and/or identification of microorganism. In one aspect of the present invention, the interrogation steps can occur in situ in the separation device or container described herein.

Abstract: The Present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s).

Abstract: A system for separating and concentrating a component of a whole material is disclosed. The whole material can include a material that has more than one component, such as whole blood that can include at least red blood cells, monocytes, and plasma. The system can include a substantially single container including a separation section and a concentration section wherein a component can be moved from the separation section, after a separation, to the concentration section to be concentrated. The concentrated component can then be withdrawn from the separation and concentration container for a selected procedure.

Abstract: In a centrifugal microfluidic device for conducting capture assays, a microfluidic platform rotates in a plane of rotation and has at least one capture surface for immobilizing a target particle of interest in the device. The capture surface oriented so that it is not parallel to the plane of rotation of the device and is positionally fixed in the device during operation of the device. The centrifugal force arising from rotation of the device forces the target particles against the capture surface. Capture efficiency is independent of the rate of flow of the fluid and independent of the rate of rotation of the microfluidic platform.

Abstract: The invention includes a method of determining the effective density of nanomaterial agglomerates in liquids, such as but not limited to physiological fluids, using volumetric centrifugation. The method of the invention allows for the development of reliable and efficient in vitro dosimetry and methods for toxicological testing of engineered nanomaterials.

Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.

Abstract: A processing system for processing raw slurry material has a barrel member, at least one transport member, and at least one separator member. The barrel member defines a processing chamber and at least one intermediate opening. The processing chamber defines a pre-processing portion and a separator portion. The at least one transport member is arranged within the pre-processing portion of the processing chamber. The at least one separator member is arranged within the separator portion of the processing chamber and configured to define at least one separator gap. As the barrel member rotates about a longitudinal axis thereof, the at least one transport member transports at least a portion of the raw slurry material through the pre-processing portion of the processing chamber, and the at least one separator member transports at least a portion of the raw slurry material through the separator portion of the processing chamber.

Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.

Abstract: This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.

Abstract: A method of transporting magnetic particles enables magnetic particles to be transported between a plurality of microfluidic chambers which are connected to one another via a fluidic connection on a radially inner side, and are fluidically separated from one another on a radially outer side. Magnetic forces and centrifugal forces are exploited to transport magnetic particles from one chamber to another across phase boundaries.

Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The tube and barrier maintain stability of one or more analyte levels, including potassium and glucose, within 10% of their initial values before centrifugation for at least four days.

Abstract: A syringe piston used in fat transplantation is structured such that free oil is easily separated from suctioned fat by a syringe piston having a filter and naturally discharged through the rear side thereof. The syringe piston without a shaft, used in fat transplantation, disposed in a syringe-shaped cylindrical vessel, includes a piston body without the shaft, a packing coupled with an outer surface of the piston body to seal between the piston body and the syringe-shaped cylindrical vessel, a free oil discharging hole communicated with the front side and the rear side of the piston body, an opening and closing device for opening and closing the free oil discharging hole, and a filtering device disposed in a passage through which free oil is discharged to filter fat and pass the free oil.

Abstract: A device for separating materials of different densities is provided. A cup body has an internal cavity configured to hold media. An inner wall defines a central body region having an upper and lower end. The upper end is wider than the lower end. An interior shoulder circumscribes the upper end of the central body region. The interior shoulder defines a neck region above the central body region and a shoulder trap below the neck region. The shoulder trap circumscribes the upper end of the central body region and is wider than the neck region. When the device is spun about a central axis, the media travels upward along the inner wall toward the shoulder trap. Relatively more dense material in the media is collected in the shoulder trap, and relatively less dense material is expelled from the device through an opening above the neck region.

Abstract: A production apparatus of composite silver nanoparticle including: a device for arranging a silver salt microparticle and at least an alcohol solvent selected from alcohols having a carbon number of 1 to 12; a raw material mixer for preparing an alcohol solution by mixing the silver salt microparticle into the alcohol solvent added more excessively than the mol number of the silver salt microparticle to make an excess alcohol solution; a reactor for generating a composite silver nanoparticle by heating the excess alcohol solution at a generation temperature PT generating an aldehyde for a generation time with a heater, in which a silver core is formed by reducing the silver salt microparticle by the alcohol solvent and/or the aldehyde and the composite silver nanoparticle having an organic coating layer originated from the alcohol solvent around the silver core is formed, and a chiller for cooling the alcohol solution.

Abstract: An apparatus may allow separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.

Abstract: Processing of a bulk liquid including particles, including use of a rotating strainer surface with openings disposed on a circumference thereof, the openings allowing an extracted liquid in the bulk liquid to pass through the strainer surface while preventing particles from passing through the strainer surface, such that a concentration of particles in the extracted liquid is less than in the bulk liquid; an extracted liquid outflow port which outputs the extracted liquid from an interior region of the rotating strainer surface; and a motor configured to rotate the strainer surface at a speed sufficient to generate a centrifugal force or turbulence at the openings sufficient to prevent the particles from clogging the openings, wherein the strainer surface is rotated and the extracted liquid is output through the extracted liquid outflow port when the strainer surface is fully submerged in the bulk liquid.

Abstract: The present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s).

Abstract: A method of extracting or removing a liquid phase from a whole sample using a centrifugal force is disclosed. Centrifugal forces are used to apply pressure to a whole sample and drive a liquid phase through a passage region that can be perforated and/or porous and maintain a drier portion within a separate container. The whole sample can be drier, which includes a remaining sample where excess or a selected amount of liquid is removed. Direct access to the separate container or area can then be made to provide for an efficient withdrawal of the drier material from the separation container.

Abstract: Fluid filtration devices, systems and methods are disclosed. The device comprises a pump-filter hybrid system that uses rotational motion to produce pressure to drive liquid through filter elements, capturing filtrate in an isolated chamber of the device and rejecting separated solids into a second isolated chamber. The fluid filtration device, which can be configured to filter a wide variety of fluids, comprises: an influent input manifold; an impeller bowl and filter assembly configured to rotate about an axis; a barrier and muting configuration to catch and distribute filtrate; a barrier and routing configuration to catch and distribute rejected solids.

Abstract: The invention concerns a centrifugal filtering device for filtering a fluid. The device comprises a rotatable inner casing forming an inner space and a rotatable outer casing forming an outer space. The device further comprises a fluid inlet, at least one filter and drive means. The drive means is configured to rotate the inner casing to create a centrifugal pressure. The pressure forces a part of the fluid contained in the inner space through the filter and to a radially outer position of the outer space. The filtered fluid forms a filtrate, the filtrate having a kinetic energy. The outer casing is configured to transport the filtrate from the radially outer position to a radially inner position of the outer space, permitting transfer of the kinetic energy from the filtrate to the outer casing, thereby permitting regaining of mechanical energy.

Abstract: A concentrator is used for concentrating a fluid, particularly a plasma component out of blood, for treatment of a patient. The concentrator apparatus includes a main housing defining a centrifuge chamber, that also holds the filter. The concentrator allows viewing of the fluid after centrifuging, with an outlet port positionable at a height corresponding to the level of the fraction of the fluid to be further concentrated. Once the fluid is centrifuged, a portion of the fluid is drawn through the outlet, and then pressured past the filter to further concentrate the fluid using the same vessel as used for centrifuging. The same plunger is preferably used to draw centrifuged fluid from the centrifuge chamber as to pressure the centrifuged fluid past the filter.

Abstract: Extracting or removing at least a portion of liquid phase from a whole sample using a centrifugal force is disclosed. Centrifugal forces are used to apply pressure to a whole sample and drive a liquid phase through a passage region that can be perforated and/or porous and maintain a drier portion within a separation container. The whole sample can be dried, which includes a remaining sample where excess or a selected amount of liquid is removed. Direct access to the separation container or area can then be made to provide for an efficient withdrawal of the drier material from the separation container.

Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The barrier rapidly hardens forming a solid barrier when triggered by a suitable energy source.

Abstract: A process is disclosed for purification of silicon source material including trichlorosilane. First, the silicon source material in liquid state with impurities vapor and the other chlorosilane or silane are passing a first high gravity rotating packed bed with porous metal, at a temperature lower than the boiling point of the silicon source material, the impurities vapor and the other chlorosilane or silane are separated from the liquid silicon source material; second, the silicon source material in liquid state is fed to a second high gravity rotating packed bed, oxygen is also fed to the second high gravity rotating packed bed to form impurity-containing siloxane complexes with higher boiling point. Finally distilling to remove the impurity-containing siloxane complexes from the silicon source material.

Abstract: A process for separating a first mother liquor stream is provided. The process comprises: separating a first mother liquor stream in a second solid liquid separation zone to produce a secondary wet cake stream and a second mother liquor stream; wherein the first mother liquor stream comprises water non-dispersible microfiber, water, and water dispersible sulfopolyester; wherein the second mother liquor stream comprises water and water dispersible sulfopolyester; and wherein the secondary wet cake stream comprises water non-dispersible polymer microfiber.

Abstract: A spin column device, which contains a rigid porous filter that retains its shape during centrifugation, chromatography methods using the device to isolate a desired substance, e.g., a biological molecule, from other substances in a mixture, and kits containing the device with one or more reagents for use in the method.

Abstract: Disclosed are a gas-liquid separator, a hydrogen generating apparatus, and a fuel cell generation system, having the same. The gas-liquid separator can include an inflow path, into which a fluid material having a liquid and a gas flows; a centrifugal path, connected to the inflow path to receive the fluid material and formed spirally such that the fluid material is separated into the liquid and the gas by difference in centrifugal forces, an outer side of the centrifugal path having stronger affinity for the liquid than an inner side of the centrifugal path; and an outflow path, connected to the centrifugal path and discharging the liquid and the gas, which have been separated in the centrifugal path. With the present invention, it is possible to efficiently separate gas such as hydrogen and liquid such as a electrolyte solution without complex devices.

Abstract: A system is disclosed for removing gas bubbles from blood during circulatory assist procedures. Such bubbles are generated, along with particulate matter, in an extracorporeal circulatory bypass system by the pump, oxygenator and other components. Current filters are inefficient at removing small bubbles that can cause neurological defects and renal and other organ failures in the patient. An active filter apparatus and method is disclosed that forces the bubbles to the center of the system where they are removed from the blood before the blood exits the filter. The filter comprises an axially elongate cylindrical shell with a blood inlet, a blood outlet and a gas outlet. A motor driven impeller spins the blood within the shell and forces the gas toward the center by centripetal force, utilizing the buoyancy effects of the bubbles in blood, whereby the bubbles can be bled off at the center of the filter.

Abstract: A centrifugal processing bag, system and method for separating the components of a mixed material is presented. The processing bag includes a hub and a first port for receiving the mixed material, where the first port includes an outlet positioned within the processing bag at a perimeter of the bag. The processing bag also including a second port having a second port inlet spaced proximate the hub and away from a central axis of the hub. The second port directs a separated material collected from the second port inlet out of the processing bag.

Abstract: This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.

Abstract: A method for the separation of particles of different densities using a step-wise gradient density extraction method as described herein where a sample is suspended in a liquid volume of an extracting medium of specific density and the particles that have a density less than or equal to that of the extracting medium of specific density can be recovered from a horizonatally rotatable hollow disk or a removable receptacle within a horizontally rotatable hollow disk designed for such purposes while the particles that have a density greater than the extracting medium of specific density form a deposit which can be cycled through the extraction process in an iterative fashion by varying the density of the extracting medium allowing the recovery of discrete particles of differing densities from a test sample.

Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The barrier rapidly hardens forming a solid barrier when triggered by a suitable energy source.

Abstract: The present invention relates to separating one or more of sand and other particulate matter from a mixture of animal waste and water. The present invention can help to control the discharge of noxious odors while processing material containing animal waste. An exemplary apparatus in accordance with the present invention includes a cylindrical housing and a non-rotating collection table. An exemplary apparatus in accordance with the present invention includes optional shield provided inside the cylindrical housing that can help to capture the particulate matter and that can also help to reduce the discharge of noxious gas and odors from the apparatus.

Abstract: Provided herein is technology relating to filtration and particularly, but not exclusively, to filters and methods for filtering by means of centrifugation.

Abstract: Methods for using a centrifuge are presented. A vessel containing a sample and a separator substance is placed within a centrifuge. Upon sufficient centrifugation, the sample separates into two or more fractions separated by the separator substance. The centrifuge exposes the separator substance to a sufficient energy to polymerize the separator substance to produce a hardened barrier between the fractions.

Abstract: A method for the separation of particles of different densities using a step-wise gradient density extraction method as described herein where a sample is suspended in a liquid volume of an extracting medium of specific density and the particles that have a density less than or equal to that of the extracting medium of specific density can be recovered from a horizonatally rotatable hollow disk or a removable receptacle within a horizontally rotatable hollow disk designed for such purposes while the particles that have a density greater than the extracting medium of specific density form a deposit which can be cycled through the extraction process in an iterative fashion by varying the density of the extracting medium allowing the recovery of discrete particles of differing densities from a test sample.

Abstract: A centrifuge (2) for separating solids from liquid of a slurry with a conveyor (12) having a hub (14) rotatable about an axis (34) and at a helical blade (16) extending axially and radially from the hub. A bowl (4) including a cylindrical section (6) extending from an upstream end of the conveyor and a conically diverging screen section (10) extending to a downstream end of the conveyor extends about the conveyor and is rotatable about the axis. The conically diverging screen section includes an angle (40) that reduces the coefficient of friction of the solids to allow a cake formed of the solids to slide in a controlled manner forward on the conically diverging screen section with minimal back pressure, but without allowing the solid cake to break loose from the conically diverging screen section and slide out of the centrifuge in an uncontrolled manner.

Abstract: A system and method for filtering solvent including a housing for receiving the solvent and a filtering media, where the solvent is moved through the filtering media without using a pump.

Abstract: The separator screen arrangement of a centrifugal basket assembly reduces separator screen wear and eases structural replacement of worn parts. The centrifugal basket assembly comprises a screen-supporting basket; a separator screen, and a series of J-shaped dam segments. The separator screen is received and supported by the basket and comprises and inlet and a circular outlet end. The dam segments each comprise a dam portion, and a rim seat portion. The rim seat portions seat upon the rim, being attached thereto in a circular manner side-by-side such that the dam portions extend toward the inlet end. The dam portions dam material directed thereagainst from the inlet end so as to uniformly spread and layer material upon the separator screen before the material exits the basket assembly. The uniformly spread and layered material reduces wear of the separator screen. Material-drying and screen-protecting methodology is further supported by the basket assembly.

Abstract: A device for isolating a component of a multi-component composition. The device includes a housing, a chamber, and a withdrawal port. The chamber is rotatably mounted within the housing. The chamber includes a chamber base and a sidewall. The side wall extends from the chamber base. At least a portion of the sidewall is defined by a filter that permits passage of a first component of the multi-component composition out of the chamber through the filter and to the housing base. The filter restricts passage of a second component of the multi-component composition through the filter. The withdrawal port extends from a position proximate to the housing base to an exterior of the device. The withdrawal port permits the withdrawal of the first component from the housing base to an exterior of the device.

Abstract: Contemplated whole blood separators tubes include a curable composition with a density intermediate to the density of serum and the cell-containing fraction. After centrifugation, the curable composition is located between the serum and the cell-containing fraction and preferably irradiated with UV light to initiate a curing reaction in which the curable composition solidifies to a barrier that is immobilized and resistant to breakdown at freezing temperatures and extended storage.

Abstract: A mixture of single-walled carbon nanotubes (“SWNTs”) is separated into fractions of enriched chirality by preparing an aqueous suspension of a mixture of SWNTs and a surfactant, injecting a portion of the suspension on a column of separation medium having a density gradient, and centrifuging the column. In some embodiments, salt is added prior to centrifugation. In other embodiments, the centrifugation is performed at a temperature below room temperature. Fractions separate as colored bands in the column. The diameter of the separated SWNTs decreases with increasing density along the gradient of the column. The colored bands can be withdrawn separately from the column.

Abstract: Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.

Abstract: A method for separating and enriching isotopes in an efficient and low-cost manner from a condensation-system (liquid or/and solid) material including two or more different isotopes by taking advantage of the sedimentation of atoms through an acceleration field by ultra-high speed rotation. The condensation-system material is placed in a sedimentation tank which is then housed in a supercentrifuge. The supercentrifuge in its rotor is rotation driven by an ultra-high speed rotation power source, and an acceleration field of energy of 100000 G to 1500000 G, i.e., about 100 to 800 m/s in terms of peripheral velocity, is applied to the above condensed (liquid or/and solid) material under such a temperature that is specified by an isotope material to be enriched. In this case, a difference in centrifugal force applied is provided between the isotopes in the condensed (liquid or/and solid) material comprising the at least two isotopes.

Abstract: Method and apparatus for separating plasma from blood in a separation vessel and further separator the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the separation vessel to receive the separated plasma.

Abstract: A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density that is configured to reach an equilibrium position in a suspension. The guide surface is carried on the buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.

Abstract: Disclosed is a separator-concentrator, such as for separating and concentrating platelet-rich-plasma (PRP) from whole blood that is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly and a concentrator assembly. The centrifugal separation assembly comprises a centrifugal drum separator and a motor having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate.

Abstract: A syringe piston used in fat transplantation is structured such that free oil is easily separated from suctioned fat by a syringe piston having a filter and naturally discharged through the rear side thereof. The syringe piston without a shaft, used in fat transplantation, disposed in a syringe-shaped cylindrical vessel, includes a piston body without the shaft, a packing coupled with an outer surface of the piston body to seal between the piston body and the syringe-shaped cylindrical vessel, a free oil discharging hole communicated with the front side and the rear side of the piston body, an opening and closing device for opening and closing the free oil discharging hole, and a filtering device disposed in a passage through which free oil is discharged to filter fat and pass the free oil.

Abstract: Separating a multi-phase mixture influent even during excessive flows of specific phases. The dynamic phase separator includes a chamber divided into two regions by an inner wall disposed radially inward relative to an outer wall. A gross separation region is defined between the inner wall and the outer wall, while a fine separation region lies inside an area defined by the inner wall and top of the chamber. Influent to be separated is fed through an inlet into the gross separation region. A plurality of porous disks are mounted to a rotatable shaft and disposed in the fine separation region. The outer and inner walls are separated by a predetermined distance sufficient to allow for adequate rotational velocity of incoming tangential flow of the influent and dwell time sufficient for natural separation of lighter phases from heavier phases within the gross separation region.