Centrifugally Extracting Patents (Class 210/781)
  • Patent number: 7354515
    Abstract: A concentrator is used for concentrating a fluid, particularly a plasma component out of blood, for treatment of a patient. The concentrator apparatus includes a main housing defining a centrifuge chamber, that also holds the filter. The concentrator allows viewing of the fluid after centrifuging, with an outlet port positionable at a height corresponding to the level of the fraction of the fluid to be further concentrated. Once the fluid is centrifuged, a portion of the fluid is drawn through the outlet, and then pressured past the filter to further concentrate the fluid using the same vessel as used for centrifuging. The same plunger is preferably used to draw centrifuged fluid from the centrifuge chamber as to pressure the centrifuged fluid past the filter.
    Type: Grant
    Filed: February 22, 2005
    Date of Patent: April 8, 2008
    Assignee: Millennium Medical Technologies, Inc.
    Inventors: Thomas Coull, Matthew R. Kyle, Louis S. Kidder
  • Patent number: 7335312
    Abstract: A centrifuge with combinations of multiple features is disclosed. In one aspect, a centrifuge for removing more dense material from a fluid medium includes a fluid separation wall placed within a sleeve. The fluid separation wall rotates around the axis of rotation. A receptacle aids in separation of the more dense material from the fluid medium. The receptacle defined in a part by a respective geometry and a respective shape. An opening extends from the void area to the outer surface to transport the more dense material to the containment zone. An excitation apparatus associated with the receptacle creates a vibration within the receptacle. The centrifuge may further include a valve ring including a valve orifice the valve ring having a first position which blocks the more dense material from exiting the receptacle and a second position that allows the more dense material to move into the containment zone.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: February 26, 2008
    Assignee: Phase Inc.
    Inventors: Curtis Kirker, Berkeley F. Fuller
  • Patent number: 7311848
    Abstract: The present invention relates to a method of monitoring a liquid fluid mixture and a system carrying out the method. The invention also relates to the use of the system for monitoring liquid fluid mixtures.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: December 25, 2007
    Assignee: AKZO Nobel N. V.
    Inventors: Matthew Rice, Hans Wijk
  • Publication number: 20070284319
    Abstract: Fluid filtration devices, systems and methods are disclosed. The device comprises, for example, an influent feed tube; an influent receiving bowl in fluid communication with the influent feed tube; and a plurality of radial arms having filters therein configured to rotate about an axis within the influent receiving bowl. The fluid filtration devices, which can be configured to filter a wide variety of fluids, comprises: an influent feed tube; an influent receiving bowl in fluid communication with the influent feed tube; and a plurality of radial arms having filters therein configured to rotate about an axis within the influent receiving bowl.
    Type: Application
    Filed: May 31, 2007
    Publication date: December 13, 2007
    Inventor: Melvin W. Cook
  • Publication number: 20070284320
    Abstract: A method and apparatus for separating blood into blood components using a separation vessel satellite bags mounted on a centrifuge rotor and a balancing assembly for the centrifuge to compensate for changes to the center of gravity.
    Type: Application
    Filed: May 22, 2007
    Publication date: December 13, 2007
    Applicant: GAMBRO BCT, INC.
    Inventors: Thomas L. MENHENNETT, Brian M. HOLMES, Charles HAKE, Daniel A. JOSEPH, Per-Olov Jan LUNDBERG, Hans LINDELL, Johan-Petter Hagstrom
  • Patent number: 7306057
    Abstract: A method for treating material, the material contaminated with contaminants, the method including: introducing material with contaminants to a system for remediation including a thermal treatment system, a quench system, a weir tank system and a condensing system; feeding a slurry of the material to the thermal treatment system and heating the material therein producing heated discharge solids and a discharge stream with liquid and solids therein; optionally, discharging the heated discharge solids and feeding them to a mill system; feeding the discharge stream to a quench system producing a cooled discharge stream which is fed to the weir tank system; the weir tank system having a clean side and a dirty side; the cooled discharge stream fed to the dirty side of the weir tank system, and from the weir tank system producing at least one stream of cleaned liquid and a stream with contaminants therein; and, in one particular aspect, remediating drilled cuttings material using such a method.
    Type: Grant
    Filed: September 20, 2004
    Date of Patent: December 11, 2007
    Assignee: Varco I/P, Inc.
    Inventors: Gary S Strong, Dale A. Pierce, Lyndon Stone, Cliff Gaddis, Bradford R Wood, Kenneth W. Seyffert, Cecil Lee
  • Patent number: 7306740
    Abstract: System and methods for collecting and preparing fat for autologous fat transplantation. The system includes a centrifuge, syringes, and filtering and transferring assemblies coupled with the syringes. Substances, including oil, fat, and denser substances (tumescent fluid, connective tissue, and other non-fat substances), are harvested into a syringe. A dye is provided or injected in the syringe. Centrifugation of the syringe stratifies the substances into a top oil stratum, a middle fat stratum, and a bottom denser substance stratum. A superficial layer of less viable fat tissue in the middle stratum is highlighted by the dye. Denser substances are filtered out of the syringes during centrifugation. Oil and the less viable fat tissue are removed through a port in the plunger head of the syringe plunger. More viable fat tissue is transferred into smaller syringes through an adapter in the assembly coupled with the syringe and the smaller syringes.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: December 11, 2007
    Assignee: Lipose Corporation
    Inventor: Robert M. Freund
  • Patent number: 7211191
    Abstract: An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. Each component may then be separated into its own storage container.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: May 1, 2007
    Assignee: ThermoGenesis Corp.
    Inventors: Philip H. Coelho, Eric Sommer, Richard Klosinski, Jim Hobbs
  • Patent number: 7189331
    Abstract: An adapter for use with a centrifuge. Features of the adapter allow for less friction during extraction of the adapter and separation efficiency by preventing disturbances to the separated materials. In addition, the adapter includes features that support the walls of a sample container and prevent force from damaging the sample container during a centrifuge separation procedure.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: March 13, 2007
    Assignee: Beckman Coulter, Inc.
    Inventors: Patrick Q. Moore, Christopher L. Stewart
  • Patent number: 7179391
    Abstract: An apparatus that allows for separating and collecting a concentrated fraction of a fluid, such as a whole blood sample, adipose tissue, or a bone marrow sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. The apparatus includes a container to be placed to a centrifuge after being filled with a whole blood sample. A buoy or fraction separator, which has a density less than that of red blood cells of a whole blood sample, is disposed in the container. During the centrifuge process the buoy separates the red blood cells from another fraction of the whole blood. After the centrifuge process is finished a plunger is used to produce at least two other fractions, including a plasma fraction and a buffy coat. Then, the buffy coat may be removed from the container without commingling the fractions of the sample.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: February 20, 2007
    Assignee: Biomet Manufacturing Corp.
    Inventors: Michael Leach, Jennifer E. Woodell-May, Joel Higgins
  • Patent number: 7166225
    Abstract: A fluid filtering device includes a plurality of filtering wells and an angling mechanism which adjusts the angle of the membranes within the filtering wells relative to a line of a centrifuge where the line is perpendicular to the axis of rotation of a centrifuge and passes through the center of a major plane of the filtering device. The angling mechanism can include a wedge located between the center of rotation of a centrifuge and a swinging bucket of the centrifuge. The angling mechanism can also be located within each filtering well and can provide individually specified angles for each membrane, relative to the line of the centrifuge.
    Type: Grant
    Filed: March 22, 2005
    Date of Patent: January 23, 2007
    Assignee: Millipore Corporation
    Inventors: Aldo M. Pitt, Sara D. Gutierrez, Thomas G. Zermani, Jeffrey Busnach, Joseph J. Raneri, James C. Groves
  • Patent number: 7131370
    Abstract: The invention relates to a centrifugal separating device and method for clarifying must during wine production, especially with a separator (7). Gas and/or gelatine and/or other additives are added to the must that is clarified in the separating device after the must has passed through the separating device and before it passes through the constant pressure valve (13) of the separating device, as the must is discharged (9), in order to obtain flotation.
    Type: Grant
    Filed: December 30, 2000
    Date of Patent: November 7, 2006
    Assignee: Westfalia Separator AG
    Inventors: Frank Schauz, Ulrich Schmid
  • Patent number: 7081206
    Abstract: The filter removes volatile, particulate and water-based contaminants from a fluid, such as lubricating oil, of a different density than the contaminants. The device has a cone shaped, jet-propelled, helical-spiral wiper rotor creating centrifugal forces that separate the volatile and heavier particulate matter. Ports in a base assembly facilitate removal of the separated contaminants. A settling tank with vertical grid filter minimizes turbulence for further separation of heavier particulate matter. A volatile tank with vertical grid filter and flow restrictor minimizes turbulence to allow volatiles to rise from the fluid. A filter tank filters out remaining particulate matter from the fluid. A combination of flow restrictors and baffles minimize cross-contamination, thereby maximizing purity of oil returned to the engine. The collection tanks are easily cleaned and reused. The compact design minimizes oil volume necessary for purification.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: July 25, 2006
    Assignee: Investors Precision Manufacturing, Inc.
    Inventor: Milton Charles Van Noland
  • Patent number: 7037428
    Abstract: A system for automatically processing blood components is described. The system includes a console, which contains all motors, pumps, sensors, valves and control circuitry, and a unique disposable set that includes a cassette supporting a centrifuge with an improved design, pump interfaces with an improved design, component and solution bags, and tubing. Various processes are implemented using a specific disposable set for each process which allows automatic identification of the process to be performed the console.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: May 2, 2006
    Assignee: Mission Medical, Inc.
    Inventors: Thomas C. Robinson, Thomas P. Robinson, Richard D'Elia, Paul Eibe, Thomas Sahines
  • Patent number: 7033501
    Abstract: An apparatus is adapted to centrifuge a container for separating a component, such as fibrin monomer, from blood or plasma. The container includes a cylindrical member, and a piston displaceable therein and a tubular piston rod, which extends through a top wall of the cylindrical member. The piston divides the cylindrical member into a first chamber positioned above the piston between the piston and the top wall, and a second chamber positioned below the piston. The apparatus includes a supporting turntable which releasably retains the cylindrical member. The supporting turntable is connected to a first activator for rotating the supporting turntable with the container about the central axis thereof. The apparatus also includes a rotatably journalled piston activating mechanism adapted to activate the piston by a second activator.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: April 25, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gautam Bhaskar, Glenn A. Joergensen
  • Patent number: 7018539
    Abstract: A process and apparatus for treating oily wastewater, such as bilge water or ballast water, generated on a ship. The process uses a combination of a centrifugal separation step and a membrane separation step, such as an ultrafiltration step. The membrane separation step uses a dense, non-porous filtration membrane. The process is able to remove both emulsified oil and dissolved oil from the wastewater to low levels.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: March 28, 2006
    Assignee: Membrane Technology and Research, Inc.
    Inventors: Anurag P. Mairal, Alvin Ng, Johannes G. Wijmans, Ingo Pinnau, Jennifer H. Ly
  • Patent number: 6994858
    Abstract: Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.
    Type: Grant
    Filed: May 3, 2001
    Date of Patent: February 7, 2006
    Assignee: Oncolytics Biotech Inc.
    Inventors: Donald Morris, Bradley G. Thompson, Matthew C. Coffey
  • Patent number: 6953550
    Abstract: This invention provides methods and apparatus for detecting and quantifying particulate matter suspended in a fluid. Specifically, the invention provides an integrated, affinity-binding based, analytical system comprising a platform for performing an affinity-binding based assay for specifically binding particulates including microbial cells, and a detection means for detecting the particulates specifically bound to a defined surface or chamber comprising the platform. Methods for using the analytical systems of the invention are also provided.
    Type: Grant
    Filed: November 30, 2003
    Date of Patent: October 11, 2005
    Assignee: Tecan Trading AG
    Inventors: Norman F. Sheppard, Jr., Alec Mian, Gregory Kellogg, Stephen G. Kieffer-Higgins, Bruce L. Carvalho
  • Patent number: 6946079
    Abstract: A method and a device for separating a component, such as fibrin I from blood, by centrifugation. The method involves feeding of blood admixed an anticlotter to a first annular chamber in a device, where the annular chamber is defined by a cylindrical outer wall and a cylindrical inner wall, both walls extending coaxially about a common axis, as well as by a top wall and a bottom wall, where the top wall or the bottom wall is formed by a piston body displaceable within the first chamber. The method involves furthermore a centrifugation of the device about the said common axis followed by a resulting liquid fraction being transferred while influenced by the piston body to a second chamber defined by an outer cylindrical wall, which extends coaxially with said common axis.
    Type: Grant
    Filed: July 16, 1998
    Date of Patent: September 20, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventor: Niels Erik Holm
  • Patent number: 6932913
    Abstract: A system and method for vibration in a centrifuge is disclosed. A centrifuge for removing more dense material from a fluid medium includes a fluid separation wall placed within a non-rotating sleeve. The fluid separation wall rotates around the axis of rotation and includes an inner surface and an outer surface with at least one receptacle formed on the inner surface of the fluid separation wall. The receptacle aids in separation of more dense material from the fluid medium by forming a void space between the inner and outer surface. An excitation apparatus associated with the receptacle to create a vibration within the receptacle. A flow path may extend through the wall from the void area to the outer surface to transport more dense material to the containment zone.
    Type: Grant
    Filed: March 11, 2004
    Date of Patent: August 23, 2005
    Assignee: Phase Inc.
    Inventors: Curtis Kirker, Berkeley F. Fuller
  • Patent number: 6890740
    Abstract: There has been invented an apparatus comprising a separation barrier for excluding denser cell materials from less dense cell materials after centrifuging of the cells so that selected materials can be withdrawn from the less dense cell materials without inclusion of the denser cell materials or clogging of sampling equipment with denser cell materials. Cells from which selected material is to be withdrawn are centrifuged, either as cells or cells in media. Once the denser cell materials are isolated in a layer by centrifugal force, an invention screen or seive is submerged in the less dense cell material to a level above the layer of denser cell materials to isolate the denser cell materials from the less dense cell materials, preventing mixing of the denser cell materials back into the less dense cell materials when the cells or the cells in media are no longer being centrifuged and to prevent clogging of sampling equipment with denser cell materials.
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: May 10, 2005
    Assignee: The Regents of the University of California
    Inventor: Donna L. Robinson
  • Patent number: 6831735
    Abstract: The analytical method having both flow cytometery and cytodiagnosis functions comprises the steps of: preparing a sample containing particulate substances such as cells and viruses; injecting the sample into a plate-like sample container; centrifuging the sample container; and using the sample container in which a distribution of the particulate substances has been formed as a preparation for analysis. The preparation is scanned with a laser beam to obtain analytical data. An analytical device for this method is also provided.
    Type: Grant
    Filed: April 10, 2002
    Date of Patent: December 14, 2004
    Assignee: Canon Kabushiki Kaisha
    Inventor: Mamoru Tsukada
  • Patent number: 6823238
    Abstract: A method and apparatus selective remove undesirable low gravity components from the return stream of drilling mud. The apparatus receives mud returned from the well borehole and transfers the mud to a tank. Mud from the tank is treated in a separation system including a plurality of mass flow sensor to monitor operation of the system.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: November 23, 2004
    Assignee: Hutchison Hayes L.P.
    Inventors: Gary L. Hensley, Lee Hilpert
  • Patent number: 6805805
    Abstract: A system and method for receptacle wall vibration in a centrifuge is disclosed. A centrifuge for removing more dense material from a fluid medium includes a vibratory device associated with the receptacle wall to create a vibratory force.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: October 19, 2004
    Assignee: Phase Inc.
    Inventors: Curtis Kirker, Berkeley F. Fuller
  • Patent number: 6802983
    Abstract: A method and system for separating impurities, such as large abrasive particles and foreign matter from an abrasive polishing slurry prior to a Chemical Mechanical Polishing (CMP) procedure performed on a surface of a semiconductor wafer. Impurities greater than about 25 microns are removed by an initial filtration process. The filtrate is then introduced to a solid bowl, sedimentation-type centrifuge to remove particles greater than 0.5 microns thereby providing a polishing slurry for final utilization in a CMP procedure that reduces damage to the surface of the polished semiconductor wafer.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: October 12, 2004
    Assignee: Advanced Technology Materials, Inc.
    Inventors: William Mullee, Glen Jenkins, Michael Jones
  • Patent number: 6783685
    Abstract: The invention is directed to an oil treatment apparatus and method for treatment of oil which transports oil to be treated from a source through a first conduit to a treatment station. The treatment station includes a filter system capable of extracting particulate material from the oil and removing the particulate material from the filter system as it is removed from the oil. The treated oil may then be transported for reuse, preferably in a continuous cycle with the source of the oil. A prefiltering system may be used to further enhance maintaining the quality of the oil and/or in efficiently treating the oil while accommodating throughput requirements. The prefiltering system may include a comminuter to reduce the size of larger particles in the oil, a coarse filtering system to remove larger particle, a system to introduce a treatment material to the oil or other systems to facilitate processing.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: August 31, 2004
    Assignee: FMC Technologies, Inc.
    Inventor: Yong Y. Hwang
  • Patent number: 6758981
    Abstract: A system and method for removing a by-product from a chemical hydride solution is disclosed. The method includes the steps of: (a) withdrawing the chemical hydride solution at a first temperature from the reactor; (b) cooling the chemical hydride solution to a second temperature below the first temperature, wherein a precipitate is formed from a portion of the by-product; (c) removing the precipitate from the chemical hydride solution; (d) heating the chemical hydride solution to a third temperature above the second temperature, to dissolve the remaining precipitate; and (e) delivering the chemical hydride solution back to the reactor.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: July 6, 2004
    Assignee: Hydrogenics Corporation
    Inventors: Antonio G. Mazza, Ali Rusta-Sallehy
  • Publication number: 20040127841
    Abstract: An improved method for separating whole blood into components and collecting a desired blood component. The method allows a desired blood component to be subjected to centrifugal forces within a separator for prolonged periods of time, yielding a cleaner cut and higher yield of the desired blood component. Whole blood is drawn from a source and pumped into a separator, the undesired blood components are removed from the separator at rates so as to build up the desired blood component in the separator. The desired blood component is only removed after a predetermined amount of the desired blood component has built up in the separator. It is preferred that the desired blood component be buffy coat and that the method be used to perform photopheresis treatments. In another aspect, the invention is a method of performing a full photopheresis treatment to treat diseases in a reduced time, preferably less than about 70 minutes, and more preferably less than about 45 minutes.
    Type: Application
    Filed: September 3, 2003
    Publication date: July 1, 2004
    Inventor: Dennis Briggs
  • Publication number: 20040108281
    Abstract: A new type of invertible filter centrifuge is proposed, where a more compact construction is obtained and where the solids component is discharged substantially independently of its moisture content. The new type of invertible filter centrifuge has no filter cloth and comprises a centrifuging drum mounted rotatably in a drum housing with a drum wall enclosing a stationary, dimensionally stable filtering medium, a shaft driving the drum in rotation, a cover sealingly closing the open end of the drum at the edge of the drum, a feed means for suspension to be filtered, with a filling pipe leading into the interior of the drum, and a drum base arranged in the interior of the drum, the drum base and filtering medium or wall of the drum being axially displaceable relative to each other in order to discharge the solid constituent mechanically from the drum.
    Type: Application
    Filed: September 26, 2003
    Publication date: June 10, 2004
    Applicant: Heinkel Aktiengesellschaft
    Inventors: Hans Gerteis, Gerd Mayer
  • Patent number: 6726841
    Abstract: Method for treating non-gelatin colloidal encapsulation waste materials in which the waste is combined, optionally, with a solvent capable of dissolving the non-gelatin colloidal encapsulation material, and any softening agent contained therein, and then treating the solvent layer to remove contaminants such as residual oils and/or particulates which may be present, to provide a purified and usable encapsulating material containing stream.
    Type: Grant
    Filed: September 4, 2001
    Date of Patent: April 27, 2004
    Assignee: A.B. Technologies Holding, L.L.C.
    Inventor: William J. Schmidt
  • Publication number: 20040069707
    Abstract: A method of isolating a charged, especially proteinaceous, compound comprises providing a prepared sample of the compound in solution, placing the prepared sample in contact with a membrane so limited in effective adsorptive surface area as to enable reversible binding to the membrane of the charged compound in the sample presented to the adsorptive surface such that solvent is removable therefrom and the charged compound is left substantially reversibly bound thereto, and eluting the compound from the membrane. Eluted compounds can then be directly subjected to mass spectrometric analysis for charcterisation of, for example, individual peptides.
    Type: Application
    Filed: August 22, 2003
    Publication date: April 15, 2004
    Inventor: Michael Naldrett
  • Publication number: 20040060870
    Abstract: A multi-stage apparatus and a process for recycling used engine coolant employs a combination of filtration, dissolved air floatation, centrifugation (hydrocyclone separation), semi-permeable nano filtration, reverse osmosis, and continuous deionization for separating ethylene glycol, with or without propylene glycol, and water from used engine coolant. The engine coolant is pre-filtered through a series of filters. The filters remove particulate contaninates. This filtered fluid is then subjected to dissolved air floatation and/or centrifugation to remove organic petroleum contaminants. Then, it is pressurized prior to being passed through semi-permeable nano filtration. The nano filtration separates the feed stream into a ultra filtration solution and a concentrated waste solution. The concentrate solution is returned to a centrifuged coolant tank for continuous circulation through the nano filtration device.
    Type: Application
    Filed: September 15, 2003
    Publication date: April 1, 2004
    Inventor: Marvin E. Haddock
  • Patent number: 6706180
    Abstract: A system and method for vibration in a centrifuge is disclosed. A centrifuge for removing more dense material from a fluid medium includes a fluid separation wall placed within a non-rotating sleeve. The fluid separation wall rotates around the axis of rotation and includes an inner surface and an outer surface with at least one receptacle formed on the inner surface of the fluid separation wall. The receptacle aids in separation of more dense material from the fluid medium by forming a void space between the inner and outer surface. An excitation apparatus associated with the receptacle to create a vibration within the receptacle. A flow path may extend through the wall from the void area to the outer surface to transport more dense material to the containment zone.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: March 16, 2004
    Assignee: Phase Inc.
    Inventors: Curtis Kirker, Berkeley F. Fuller
  • Patent number: 6656430
    Abstract: This invention provides methods an apparatus for detecting and quantifying particulate matter suspended in a fluid. Specifically, the invention provides an integrated, affinity-binding based, analytical system comprising a platform for performing an affinity-binding based assay for specifically binding particulates including microbial cells, and a detection means for detecting the particulates specifically bound to a defined surface or chamber comprising the platform. Methods for using the analytical systems of the invention are also provided.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: December 2, 2003
    Assignee: Tecan Trading AG
    Inventors: Norman F. Sheppard, Jr., Alec Mian, Gregory Kellogg, Stephen G. Kieffer-Higgins, Bruce L. Carvalho
  • Patent number: 6653400
    Abstract: This invention provides a method for producing a saponified ethylene-vinyl acetate copolymer in which visible imperfections (particularly fish eyes) of the saponified copolymer is inhibited. In this invention, a mixture solution is prepared by adding water to a methanol solution after saponifying an ethylene-vinyl acetate copolymer, and insoluble materials are removed from this mixture solution. Various types of filter or centrifugal separator are used to remove insoluble materials. It is preferable that the weight ratio of methanol to water is from 5:5 to 9:1, the concentration of the saponified copolymer is from 30 to 60 wt %, and the temperature is from 55 to 80° C. This method is particularly suitable for producing a saponified ethylene-vinyl acetate copolymer having an ethylene content of 20 to 70 mol % and a saponification degree of at least 95 mol %.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: November 25, 2003
    Assignee: Kuraray Co., Ltd.
    Inventors: Takaharu Kawahara, Toshio Tuboi
  • Patent number: 6612975
    Abstract: A blood centrifuge with a drive assembly for transmitting an input rotation speed to a rotor with a sample reservoir at a desired rotation ratio. The drive assembly includes a base and an outer shell mounted to the base to rotate at an input rate. A bottom pulley is rigidly mounted to the base and attached to the outer shell with bearings. A top pulley is mounted to a center shaft of the outer shell to rotate with the outer shell about the central axis of the centrifuge. An internal drive belt is provided to transmit the rotation to the top pulley via a pair of transversely mounted idler pulleys that rotate with the outer shell. The top pulley is thus rotated at twice the input rate but in the same direction. A rotor assembly with the sample reservoir is attached to the top pulley to separate blood components.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: September 2, 2003
    Assignee: Medtronic, Inc.
    Inventors: David Malcom, Victor D. Dolecek
  • Patent number: 6596179
    Abstract: Apparatus for withdrawing whole blood from a donor, separating the whole blood to obtain a target cell population and returning a selected one of either the target cell population or at least a portion of the whole blood remainder to the donor or patient. A disposable separation inset for use in association with a rotatable separation device of the apparatus may also be provided. The disposable inset may include a chamber for receiving a cell suspension that includes the target cell, a receptacle for containing particles having a binding site for selectively binding to the target cell and a means for introducing the particles into the chamber.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: July 22, 2003
    Assignee: Baxter International Inc.
    Inventors: Richard Giesler, John R. Chapman, Dale R. Ellis, Daniel F. Bischof
  • Patent number: 6589155
    Abstract: A belt-driven blood centrifuge with side-mounted drive motor for rotating the centrifuge at a rotation speed selected to separate blood components. The centrifuge includes a drive shaft assembly rotated at an input rotation speed and a rotor assembly rotatably linked to the drive shaft assembly rotated at an output rotation speed twice the input rotational speed. A drive motor is provided with a drive pulley to drive a belt, a chain, and the like to provide the motive force to rotate the drive shaft at the input rotation speed. In one embodiment, a belt is provided to contact both the pulley of the drive motor and an outer surface of a rotatable shell of the drive shaft assembly. A base is included in the centrifuge upon which the drive shaft assembly is mounted. The drive motor is positioned adjacent the drive shaft assembly and mounted on the base.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: July 8, 2003
    Assignee: Medtronic, Inc.
    Inventor: Victor D. Dolecek
  • Patent number: 6565809
    Abstract: The present invention provides a specimen processing system for centrifuging a specimen such as blood and then dispensing the specimen. This system comprises a dispense error specimen removing unit for removing a specimen in which a dispense error has been caused due to a fibrin in a dispense process, a feedback unit for injecting fibrin-decomposing beads into the specimen removed by the dispense error specimen removing unit and feeding the specimen containing the beads back to a centrifuge process, a reprocess control unit for causing the specimen fed back to the centrifuge process by the feedback unit to be centrifuged again, and a system controller for automatically controlling the dispense error specimen removing unit, the feedback unit, and the reprocess control unit.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: May 20, 2003
    Inventor: Teruaki Itoh
  • Patent number: 6547972
    Abstract: The invention relates to a centrifuge comprising a rotating drum (1) and comprising an ejection element (2) which rotates together with the drum in order to eject a cake (3) of solids, which is deposited on the inner side of the drum, in the axial direction (4). The ejection element (2) has a helix (5) which extends over the length of the drum. The helix (5) and the drum (1) are kinematically connected in such a manner that a reference point (A) at the circumference of the helix executes a rotational movement relative to the drum in the form of a sawtooth line (6, 8), with a first flank (7) of the sawteeth (8) corresponding approximately in its inclination (&agr;) to the pitch (&bgr;) of the helix whereas a second flank (9) of the sawteeth (8) corresponds to an approximately axial ejection movement.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: April 15, 2003
    Assignee: Ferrum AG
    Inventors: Werner Stahl, Harald Reinach
  • Publication number: 20030034314
    Abstract: A system and method for receptacle wall vibration in a centrifuge is disclosed. A centrifuge for removing more dense material from a fluid medium includes a vibratory device associated with the receptacle wall to create a vibratory force.
    Type: Application
    Filed: August 13, 2002
    Publication date: February 20, 2003
    Applicant: Phase Inc.
    Inventors: Curtis Kirker, Berkeley F. Fuller
  • Patent number: 6514421
    Abstract: An improved screen basket for use with a centrifuge includes two adjoining screen sections. The first screen section is formed from a wear resistant material and is located proximate to the point at which slurry is introduced into the basket. The length of the first screen section is chosen so that the majority of potential wear caused by the abrasive slurry occurs within the first section of the basket. The second screen section is preferably formed from less expensive materials, such as steel wedge wire. The second screen section smoothly joins the first screen section and provides for further dewatering or separation of the accelerated slurry so that a dry cake is produced by the centrifuge.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: February 4, 2003
    Assignee: Baker Hughes, Inc.
    Inventors: Wallace Woon Fong Leung, Nicholas R. Frohlich, Jr.
  • Publication number: 20020153333
    Abstract: A method for producing a work product including the steps of receiving a first fluid composed of a liquid, a target substance and at least one residual substance; passing the first fluid through a first work station for separating the residual substance from the first fluid to produce a secondary fluid substantially composed of the liquid and the target substance; and treating the secondary fluid to reduce the proportion of the liquid relative to the target substance in the secondary fluid to form the work product.
    Type: Application
    Filed: April 23, 2001
    Publication date: October 24, 2002
    Inventor: John J. Minazzoli
  • Publication number: 20020134738
    Abstract: In melting thermoplastic material, particularly in the form of strip-like or fibrous refuse, where the material is melted through contact with a liquid heat-transfer medium and is then separated from the heat-transfer medium, and to assure a high degree of effectiveness and to maintain a high level of quality in the molten material, it is provided that steam at a temperature distinctly higher than the melting temperature of the material is used as a heat-transfer medium and is conducted over the introduced material, the molten or at least semi-molten material is entrained by the flowing steam and is then separated from the steam at a temperature lying above the melting temperature of the material, and the steam is returned to the circuit.
    Type: Application
    Filed: November 16, 2001
    Publication date: September 26, 2002
    Inventors: Gennady Volokitin, Viktor Gapeev, Serguey Zotov
  • Patent number: 6440316
    Abstract: Methods of improving the efficiency of solid-liquid separation during centrifugal filtration have been developed. They consist of increasing the pressure drop across the filter cake using extraneous means such as increasing the gas pressure inside a filter chamber and/or applying vacuum on the outside. The extraneous means of increasing the pressure drop is designed to increase the rate of removing liquid (water) during the drainage period of the centrifugal filtration process and, hence, lower the amount of the residual liquid (water) left in the filter cake.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: August 27, 2002
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Roe-Hoan Yoon, Ramazan Asmatulu
  • Patent number: 6426010
    Abstract: The invention concerns a device for separating the constituents of a heterogeneous mixture and its uses. Said device comprises a separation chamber (100, 250, 350, 450, 650, 724, 850, 903, 1106) having a one of its ends an inlet and at the other an outlet comprising a first ring-shaped orifice (110, 210, 310, 410, 510, 610, 710, 810, 919) coaxial with said chamber, and a second ring-shaped orifice (111, 211, 311, 411, 511, 611, 711, 811, 920) coaxial with said first ring-shaped orifice and whereof the external diameter is smaller than said first ring-shaped orifice internal diameter. The invention is characterized in that said separation chamber has a cylindrical shape and said first orifice external diameter D1 is smaller than said chamber internal diameter D0. The invention also concerns a method using said device.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: July 30, 2002
    Assignee: Total
    Inventors: Yves Lecoffre, Jean-Claude Gay
  • Patent number: 6383394
    Abstract: The invention relates to a method for rendering waste sorbent material recyclable. The method includes collecting polymer-based sorbent materials containing one or more solvents, treating the waste material in a centrifugal treatment system for removing the solvents from the polymer-based sorbent materials whereby the sorbent materials have a residual solvent content that renders the materials non-hazardous for transportation to a remote recycling site. The treatment system includes a fume collection system and a centrifuge disposed in the fume collection system. The sorbent materials are charged into the centrifuge and the centrifuge is operated for extractive removal of solvents therefrom and collection of the extracted solvents. The sorbent materials are rendered non-hazardous by the centrifugal treatment system enabling the materials to be taken off site for use in making recycled parts.
    Type: Grant
    Filed: June 14, 2001
    Date of Patent: May 7, 2002
    Inventors: David L. Briggs, John K. Clement, Jr.
  • Patent number: 6375855
    Abstract: A device for concentrating and/or purifying macromolecules in a solution has a concentration chamber (1) with a sample reservoir (2) for a liquid sample to be processed, a filter (3) for filtering the liquid sample, and a filtrate container (4) for collecting the filtrate. A gas pressure differential is created and maintained across the filter and a sealing cap (5) for the sample reservoir (2), which has an opening (6) for permitting gas flow in one direction and blocking aerosol or liquid flow in an opposed direction. The present invention also provides apparatus and methods employing the device.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: April 23, 2002
    Assignee: Vivascience, AG
    Inventor: Vincenzo Vassarotti
  • Publication number: 20020040872
    Abstract: An apparatus and method for mincing a gel includes a gel mincing tube and a mesh material. The mesh material extends across the end of the tube. To subdivide a gel using the mincing apparatus, a gel is placed upon the mesh material in the mincing tube, the mincing tube, mesh material and the gel are spun in a centrifuge, forcing the gel through the mesh material so that the gel is subdivided into generally uniform smaller fragments. The mesh material may be secured to a tube in the form of a nesting tube. The nesting tube nests within the opening of a recovery vessel. The mesh material may be placed in series with a conditionally porous membrane in the nesting tube. Centrifuging the nesting tube and the recovery vessel subdivides gel material into fragments by forcing the gel through the mesh material. The gel subsequently falls upon the membrane, and may be treated on the membrane to extract or otherwise treat analytes in the gel material.
    Type: Application
    Filed: July 18, 2001
    Publication date: April 11, 2002
    Inventors: Roumen A. Bogoev, Scott E. Whitney, Joseph W. Amshey
  • Patent number: 6368513
    Abstract: An assembly for automatically and continuously purifying a polluted fluid P includes a main separator 1, a secondary separator 2 having a centrifuge 21 and filter 22 therein, and a backwashing device 11. In operation, the backwashing device returns a fraction of purified fluid E1 to backwash the main separator. The resulting backwashing fluid F is then delivered to the secondary separator via a multi-port valve V where the backwashing fluid is centrifuged and/or filtered to remove impurities therefrom.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: April 9, 2002
    Assignee: Alfa Laval Moatti SNC
    Inventors: Théophile Christophe, Jean-Claude Moatti