Abstract: A break away overcap is used for maintaining a closure in sealing engagement with the open end of a vial. The overcap is molded from a fracturable plastic and is provided with a pair of spaced, parallel score lines or V-grooves extending across the top wall of the overcap and downwardly of the cap skirt to the lower edge thereof on each side of the cap. Thumb and finger engaging portions are provided at the lower edge of the skirt adjacent the terminal ends of the score lines so that by pushing inwardly on the thumb and finger engaging portions, the overcap breaks into three pieces to thereby expose the closure for insertion of a syringe needle therethrough into the vial for removal of the vial contents therefrom.

Abstract: A resealable transfer assembly for a container such as a bottle or vial featuring a membrane for selectively opening or sealing a fluid path between the bottle and a medical delivery device introduced into the assembly. The assembly includes a body disposed on the bottle, and a luer connector hub which may be separately provided with the body or formed integrally therewith. A free plug rests in a cavity defined within the luer connector hub. The free plug includes an orifice dimensioned to accept a luer tip associated with the medical delivery device. A membrane, preferably formed from an elastomeric material, is secured across both the opposed end of the luer connector hub and the open top of the bottle, and may be retained between the top surface of the bottle and the body. The membrane preferably includes a central area sealing the opposed end of the luer connector hub from the open top of the bottle, with one or more fluid openings defined on a portion of the membrane outside of the central area.

Abstract: A connector for connecting two containers includes a first portion releasably secured to the neck of the first container and a second portion having an access opening. A closure member for sealing the access opening of the connector includes a cover for sealably closing the access opening, the cover being fixed to the connector so as to include a breakable point of attachment and a zone of weakness disposed on the periphery of the cover. The cover includes a tab disposed generally perpendicular to the cover and a strut angularly disposed between the tab and the cover such that the exertion of pressure substantially normal to the tab causes the cover to release from the connector at the zone of weakness and the rotation of the cover causes release of the cover from the connector at the breakable point of attachment.

Abstract: A plastic cap is provided which is capable of assuring a high sealing property and is advantageous for protection of the environment because of being readily subjectable to disposal of waste or burning treatment after using a container. The plastic cap comprises a drum part covering a mouth part of the container and sealing material and a top plate positioned on a top wall of the drum part, in which the drum part has, on the inner wall thereof, a protrusion part or wedge-shaped part to be engaged with an annular protrusion on the outer periphery of the container mouth part. A window part opens at the center part of the top wall of the cap drum part, and the outer edge of the window part and the lower part of the top plate are connected through several bridged parts.

Abstract: A lyophilization closure assembly for a container or vial is disclosed. The lyophilization closure assembly is self-supporting with the container and may be employed with the container during a lyophilization process, eliminating the need for a separate crimping operation outside of the sterile environment in which lyophilization is conducted. The lyophilization closure assembly includes a body with a skirt disposed around the rim of the container. The skirt features one or more deflectable abutments and one or more deflectable latches positionable about the rim of the container, and defines one or more vapor passages. An elastomeric closure is retained within the body for sealing the open top of the medicament container. The elastomeric closure features a plug for sealing the open top of the container and a top surface facing away from the open top of the container. The body defines an opening over the elastomeric closure that delimits an access area on the top surface of the closure.

Abstract: A sterile closure assembly for a container or vial includes an elastomeric closure for sealing the open top of a medicament container. The elastomeric closure features a plug for sealing the open top of the container and a top surface facing away from the open top of the container. A washer is secured in surface contact with the top surface of the closure. The washer defines an opening that delimits an access area on the top surface of the closure for access by a fluid delivery device such as a syringe. A membrane is removably secured over the washer and hermetically encloses the access area of the elastomeric closure. The sterile closure assembly can be provided pre-assembled in a sterile state to assure the sterility of the top surface of the closure, obviating the need to sterilize the top surface of the closure, such as with an alcohol solution, prior to use of the vial.

Abstract: A method is provided for reducing particle formation during manufacture of shell caps for containers such as pharmaceutical containers. The method entails providing a solid polymeric coating on substantially all surfaces of the shell caps to form coated shell caps before permitting the coated shell caps to contact each other or other objects. A pharmaceutical container which employs the shell caps also is provided. The container comprises a vial for storing medicinal compositions therein and a shell cap for sealing the vial. The shell cap includes a hollow metallic preform and a solid polymeric coating which substantially completely encapsulates the preform.

Abstract: A combination stopper and shield closure for sealing the open end of an evacuated body fluid collection tube to retain the vacuum therein. The stopper is retained within a central aperture in the shield by means of an upper and lower flange, the upper flange having a convex surface for directing residue body fluid away from the center of the flange to reduce contamination. The closure also includes a gas-barrier bonded to the stopper and/or shield to increase the vacuum seal and cam followers extending from the bottom of the shield to interact with cams on the outer surface of the tube to facilitate closure twist-off. In addition, the closure includes flexible tabs around the bottom of the shield to prevent the tube/closure assembly from being pushed out of a needle holder during body fluid collection.

Abstract: An overcap assembly for a gear finish vial having a cap constructed and arranged to contain either a stopper-type closure or a sealing disc closure. A plurality of radially inwardly extending ribs are provided in the cap to maintain the closure in the cap and to cooperate with teeth on the gear finish to prevent turning of the cap assembly when in the sealing position on the vial. A plurality of inwardly extending tabs are provided on the lower end of the cap for selectively engaging shoulders on the vial neck for holding the overcap assembly upwardly from the neck of the vial in an unsealed position during the lyophilization procedure and downwardly on the neck of the vial when in the sealed position.

Abstract: A needleless dosage transfer system for filling medicating devices such as syringes or needleless cannulas to minimize the likelihood of an unwanted needle stick and to avoid the initial cost of a needle as well as the disposal cost of the needle. A vial has a body portion (20) formed with flexibly deformable walls and defines a blind bore. An opening of the vial includes a tapered section adapted to frictionally fit over a taper of a male luer-type fitting commonly found on syringes and needleless cannulas. By deforming the walls of the vial, fluid is forced from the vial into a syringe. The opening of the vial (10) is protected with a cap and includes a scoreline which, when fractured, defines the opening. The cap to be removed from the vial prior to its use is fabricated as one piece with the vial in order to assure sterile conditions during manufacture and filling. A tab is associated with the cap which lists the ingredients within the vial. The vial also supports an area which lists the vial's contents.

Abstract: A combination stopper and shield closure for sealing the open end of an evacuated body fluid collection tube to retain the vacuum therein. The stopper is retained within a central aperture in the shield by an upper and lower flange, the upper flange having a convex surface for directing residue body fluid away from the center of the flange to reduce contamination. The closure also includes a gas-barrier bonded to the stopper and/or shield to increase the vacuum seal and cam followers extending from the bottom of the shield to interact with cams on the outer surface of the tube to facilitate closure twist-off. In addition, the closure includes flexible tabs around the bottom of the shield to prevent the tube/closure assembly from being pushed out of a needle holder during body fluid collection.

Abstract: An arrangement (A) on infusion bottles (1), or the like, having a cover (7) which has several foil-covered puncture regions (13), which cover is held by a cap (8). In order to obtain individual accessibility despite the overall covering, the cover foil (15) has an intended tear line (17) between the puncture regions (13) and forms, on both sides of the intended tear line (17), grip tabs (18) which protrude beyond the contour of the cap (8).

Abstract: A tear-off safety closure is described in particular for ensuring authenticity and for additional sealing of a bottle-shaped container containing especially pharmaceuticals which is already closed by a disk-shaped or plug-shaped sealing element. The cap surface and the closed flange-shaped jacket of the closure enclose the sealing element and the rim of the container neck which has an outwardly projecting ridge. The closure has a tear-out part which can be detached to expose the surface of the sealing element, e.g., for piercing with a hypodermic needle. The jacket has retaining devices which are arranged on its inner surface at a distance from its lower edge and which engage under the lower edge of the ridge. The closure is produced from plastic in its entirety and so as to form one piece, in particular from thermoplastically deformable plastic such as polypropylene or polyamide.

Abstract: A method is provided for reducing particle formation during manufacture of shell caps for containers such as pharmaceutical containers. The method entails providing a solid polymeric coating on substantially all surfaces of the shell caps to form coated shell caps before permitting the coated shell caps to contact each other or other objects. A pharmaceutical container which employs the shell caps also is provided. The container comprises a vial for storing medicinal compositions therein and a shell cap for sealing the vial. The shell cap includes a hollow metallic preform and a solid polymeric coating which substantially completely encapsulates the preform.

Abstract: A lid for a container, which is easy for separated disposal. The lid has a main body portion (1a) and a projected portion (1b) integrally formed at the substantially central portion of the upper surface (1a1) of the main body portion (1a), whereby the lid (1) for the container covers an opening portion of a bottle (container) (2) and a seal plug for blocking this opening portion.

Abstract: A capsule of plastic material for infusion bottles comprises a capsule body adapted to be fitted on a neck of a bottle for retaining a pierceable plug in place, and a capsule cap to be fitted on the capsule body, the capsule body having a top wall provided with a hole and a downwardly extending annular ridge formed around the hole at a distance from the latter, the capsule cap having a plug formed so as to fit into the hole of the capsule body and provided with an annular rim on its periphery so as to be folded outwardly and to fit into a space defined by the pierceable plug, the top wall of the capsule body and the annular ridge of the capsule body.

Abstract: A vial holder assembly (2) includes a generally conventional vial (4) housed within a vial holder (6). Vial holder includes a cup-shaped body (8) and a removable lid (16) mounted to the open end (14) of the body to enclose the vial therein. In one embodiment the lid is designed to coact with or engage with a plastic removable cap (46) mounted to the top of the vial. The removable cap is attached to an annular, frangible central region (42) of the metal closure (38) used to secure the resilient septum (40) to the vial. Removing the cap simultaneously removes the lid and frangible central portion to provide user access to the septum. Another embodiment positions the vial within the body using locating/shock absorbing members (18, 24) situated between the sidewalls (10, 23) and the bottoms (26, 12) of the body and the vial. These accommodate different size vials and help to prevent damage to the vial from physical abuse.

Abstract: A closure with a tamper-indicating cap for injection and infusion bottles includes a holding part (3) for a seal (5), and a cap (1) with a downwardly extending edge (2) arranged between the holding part (3) and the seal (5). This arrangement prevents the seal from dropping into the bottle neck when the closure is pierced by a needle or cannula.

Abstract: A parenteral solution container having a dual use access port used for both the administration of fluids to a patient as well as for the addition of fluids to the container, includes a generally cylindrical wall with an axial passage therethrough. A fluid-tight sealing means, having a reseal member that includes a slit therein to enable the reseal member to be pierced with a blunt, metal cannula, or sharp needle is removably attached to the dual use access port. When the dual use access port is used in its fluid addition capacity, the reseal member is attached to the wall and a blunt cannula is passed through the reseal member. Once the blunt cannula has been completely inserted, fluids may be added to the container. To use the dual use access port in its administration capacity, the sealing means is completely removed from the wall. A piercing pin is inserted into the wall creating a fluid-tight seal so that fluids may be administered to a patient.

Abstract: A combination stopper and shield closure for sealing the open end of an evacuated body fluid collection tube to retain the vacuum therein. The stopper and shield are made by co-injection molding with the stopper being retained within a central aperture in the shield by means of an upper and lower flange or a plurality of plugs extending from the stopper into the shield. The upper flange has a convex surface for directing residue body fluid away from the center of the flange to reduce contamination, a gas-barrier to increase the vacuum seal and prevent contamination, cam followers in the base of the shield to interact with cams on the surface of the tube to facilitate closure twist-off, and flexible tabs around the base of the shield to prevent the tube/closure assembly from being pushed out of a needle holder during body fluid collection.

Abstract: A closure for an injection bottle is disclosed which has an insert part for covering the mouth of the bottle, a cylindrical section having an inside diameter which is substantially identical to its length, the cylindrical section having a sealing lip on an inner circumferential surface for allowing sealed insertion of a syringe, and an intermediate ring connecting the cylindrical section to the insert part, the intermediate ring having an essentially Z-shaped cross section.

Abstract: In accordance with this invention, there is provided a closure arrangement for medication containers comprising an elastomeric stopper comprising a tear-away member which blocks a passageway defining a conical luer taper and a cap comprising means for engaging the tear-away member, whereby the engaged tear-away member can be readily torn away by a user by rotating the cap or by pulling the cap off the container in an axial direction. The closure arrangement reduces the risk of particulate contamination associated with stoppers adapted to be ruptured with a luer nozzle.

Abstract: Stoppers for medicine vessels are disclosed. Such stoppers comprise an insert having one end frictionally engageable within an opening in a medicine vessel. Such inserts' other ends have a fitting, e.g. a luer complimentary with a luer on an opening in the medicine vessel. The fitting allows the contents of the medicine vessel to be withdrawn without using a sharp object, such as a needle.

Abstract: A closure cap for the sterile sealing of a pharmaceutical bottle is disclosed. The bottle is closed with a rubber elastic sealing element that is covered by a flanged cap having a lid region and a flanged border that covers the bottle neck and is connected with the bottle neck in a border zone below the border of the bottle neck. The lid region is covered by a plastic lid and is connected to the plastic lid in its center region at a first attachment area that is enclosed by a partially circular tear line. The plastic lid is provided with a cord-like predetermined bending line. The lid region and the plastic lid are also connected to each other outside the tear line with a second attachment area, and the groove orthogonally intersects an imaginary connection line connecting the centers of the first and second attachment areas.

Abstract: A closure unit for a container for storing and handling flowable products is made from at least two different thermoplastic materials, the different materials fulfilling different functions. A basic thermoplastic material (A.2) is used for sealing against the container (G.2), and an area made of another different thermoplastic material (B.2,C) is provided to fulfill additional sealing functions, to increase mechanical stability, to have a reduced permeability, and to provide increased elasticity for additional opening and closing and/or absorption characteristics. The closure unit is produced by a multimaterial injection molding process, so that contact surfaces between the different thermoplastic materials can be interconnected by reversible or irreversible positive engagement and/or by more or less pronounced melting into one another. The closure unit is in two parts and comprises a pouring part (1.2) and a closure part (2.2), or is in one part.

Abstract: Disclosed is a stopper for use with containers to provide needleless access to the container with a cannula having a blunt penetrating tip. Also disclosed is a system comprising the stopper, container and cannula. The stopper includes a disc having an upper face and a lower face, and a plug extending from the disc into the container. Also included is a diaphragm, defined by a target region in the upper face and a cross channel in the disc for controlling the force needed to penetrate the stopper with the cannula. The plug includes a first inward surface for guiding the cannula and a second inward surface for engaging the cannula to minimize wetting of the outside of the cannula. In a preferred embodiment, the first surface extends down from the cross channel on the lower side of the disc, radially outwardly to a maximum diameter and the second inwardly facing surface extends down from the first surface radially inwardly to a minimum diameter to form the cannula seal.

Abstract: A closure for a medicine bottle, the closure having a flanged cap for covering the bottle mouth and having in the region of its base a tear-out section defined by a weakened line. A cover having a front and a rear part connected by an articulation is disposed over the flanged cap. The front part attaches to the tear-out section of the flanged cap at a first attachment area. The rear part of the cover is connected to the flanged cap outside the tear-out section at a second attachment area. When the front part of the cover is lifted up, the tear-out section is removed to provide access to the bottle. If the front part is pulled even further, the entire closure can be removed with ease from the bottle, especially if weakened lines extending from the second attachment area are provided. The closure may also be developed as a medicine bottle closure with a sealing element through which a syringe may be inserted.

Abstract: A plastic closure cap, especially for glass containers, includes a lid part to be pulled off exposing a seal or an opening. A sleeve part surrounds a bottle neck of the container. Grippers are secured on the sleeve part and are pivotal at material weak points at the sleeve part. The grippers abut one another in flush fashion in a closing position and are joined to make a closed surface encompassing the bottle neck. The grippers have sides pointing toward one another. The grippers are rectangular as seen in a plan view and curved as seen in cross section. Tabs are associated with the grippers. The sides of the grippers and the tabs face one another and have alternating profiling mutually complementing one another in the closing position. The sides of the grippers are beveled toward the inside and overlap one another in the closing position.

Abstract: A system for pharmaceutical product identification, comprising a closure on a pharmaceutical container, including a cap seal having a dependent skirt and an upwardly facing top. The seal has a first identifying indicia and the removable overcap protecting the closure has a second identifying indicia thereon. The first and second indicia cooperatively conveying information to the user of said container.

Abstract: An infusion bottle having a partial section of its bottom wall which bulges outward in a cup-like manner and which can be pierced in the region of its bottom wall by an infusion spike. A cup-shaped cover cap is provided which can be placed thereon from the outside and connected in liquid-tight manner. The cover cap has a cover bottom with a central region which can be removed. A clamping ring for the infusion spike is located between the cover bottom and the bottom wall of the bottle. The clamping ring is in the form of an O-ring and has an inside diameter which is smaller than the diameter of the central region. The clamping ring contacts the bottom wall of the bottle and the cover bottom with initial tension and has an outside diameter which is greater than that of the central region.

Abstract: A container system for reagents and other substances used in a medical diagnostic apparatus. The container system includes a vial made of blow-molded plastic, which can withstand lyophilization. The bottom portion of the vial has an annular groove and is shaped as a truncated cone below the annular groove. An auxiliary member can be snap-connected to the vial at the annular groove so that the vial will stand upright on a flat surface and contains a central aperture through which the vial remains in contact with the flat surface. The container system also includes a stopper at the mouth of the vial and a snap-on plastic cover to secure the stopper. The cover has a tab which is kept at a raised position by a lifter protrusion which bears against the stopper. The cover has tearslots which are ripped when the tab is pulled. One of the tearslots is shorter than the other and keeps the tab from being entirely detached from the remainder of the cover when the tab is pulled.

Abstract: A stopper sealing for an injectable fluid bottle suitable for protection of an upper surface of a rubber stopper of the bottle from contamination. The sealing cap comprises a sealing member for sealing the upper surface of the rubber stopper to prevent contaminant infiltration onto the upper surface of the stopper, an aluminum cap member engaging with the sealing member and covering the uppermost part of the bottle, and a synthetic resin cap member covering the aluminum cap member and engaging with the sealing member. The aluminum cap member has a center opening for receiving the sealing member and remains on the upper section of the bottle when the sealing member is removed from the bottle. The resin cap member is removed together with the sealing member from the bottle and has a center opening for receiving the sealing member, and a plurality of vertical slots; on its side inner surface for providing spaces between it and the aluminum cap member.

Abstract: A cap assembly for an enteral feeding container having an inner and outer cap. The inner cap has an upper end forming a tray with an inner peripheral lip and an outer peripheral lip, A flexible inner membrane covers the inner side of the tray of the inner cap to form a seal between the neck of the container and the tray. An outer membrane is placed over the outer side of the tray to form a sealed chamber, A cavity containing an appropriate disinfectant is centrally formed in the tray for receiving an enteral feeding tube spike when the outer membrane is removed, Access to the cavity is achieved by first removing the outer cap, then stripping away the outer membrane.

Abstract: A bottle top that comprises a tough plastic outer cap (11), a tough plastic inner cap (6) and a soft polymer stopper (4). The stopper fits inside the inner cap. The bottle has a bead (3) around its neck. The wall of the composed of several vertical strips (9). The strips are resilient radially outward and are held against the neck of the bottle by the outer cap. The bottom ends of the strips have a beveled-in edge (5) that engages the bottom edge of the bead, forcing the stopper against the upper surface of the bottle's neck. At least one area (8) of the inner cap's roof rips out. The outer cap has a hole over the rip-out area of the inner cap and screws over a thread (10) on the resilient strips that constitute the wall of the inner cap.

Abstract: A closure device for use with a container having an open neck finish, including an inner cap having a skirt terminating in an open end which engages the outside diameter of the finish. The inner cap is sized to initially engage the finish. The skirt has circumferentially spaced slits extending, which may function as lyophilization ports, which permit the inner cap to expand upon an axial closing force and engage the bottom of the finish. A liner is positioned in the inner cap proximate the closed end and is compressed against the finish when the cap is moved to alignment with the bottom of the finish. An outer cap is locked on to the inner cap in pre-assembly which then encloses the inner cap after complete assembly to seal and compress the liner between the finish and the inside face of the inner cap.

Abstract: A system for pharmaceutical product identification, comprising a closure on a pharmaceutical container, including a cap seal having a dependent skirt and an upwardly facing top. The seal has a first identifying indicia and the removable overcap protecting the closure has a second identifying indicia thereon. The first and second indicia cooperatively conveying information to the user of said container.

Abstract: The present invention relates to a closure cover (V) for infusion or transfusion bottles, having a stopper (6) which is adapted to the bottle neck (3) and is extended over by a cap (8) which is anchored by undergripping on the bottle neck (3), and it proposes in order to obtain a solution which is particularly advantageous from a structural standpoint, that the undergripping of the cap (8) is obtained by resilient individual tongues (10) which are secured in the undergrip position by a sliding ring (15) surrounding them, the cap having tabs biased outward from the bottle neck for serving at the same time to secure the sliding ring (15) in its support position.

Abstract: A pharmaceutical vial containing a quantity of an injectable drug intended to be withdrawn by introducing a hypodermic needle through the vial neck, the vial being rendered tamper-evident by means of a stretched elastic member which will rupture when penetrated by a needle, to make visible the needle insertion within the vial.

Abstract: A quick release tamper evident closure device for disposable fluid medical storage bags. The closure device comprises an outlet port section and a closure cap section sealed together. The outlet port section is sealed to the bag and includes a tubular member for discharging the fluid in the bag. The outer end of the tubular memeber extends inside a cavity formed in the cap section. A tear path is formed around the cap section for severing the cap section from the port section to provide access to the tubular member. The tear path includes opposed curved portions merging into an apex. A handle extends outward from the cap section and aligned with the apex for applying an outward force which is initially concentrated at the apex, to cause ripping of the closure cap at the apex and then along the remainder of the tear path. The handle includes an opening and is flexible for varying the dimensions of the opening to accommodate the various sized finger inserted therethrough.

Abstract: An elastomeric member for occluding a medical terminal such as a junction terminal to provide a seal and penetratable to establish fluid connection by a blunt needle or cannula in which improved security against passage of contamination is provided. The needle or cannula preferably passes through a perforated passage. The passage can have at least two portions, one having a slit for normally sealing tightly in the absence of a cannula or needle and the other having a bore communicating with the slit and closely conforming to the cannula surface. Other sealing arrangements are detailed.

Abstract: A cap for a container having a slit seal and semi-cylindrical spring seal closure members that abut the inner container wall and contact the slit seal at two points spaced from the center of the slit seal. The spring members permit the flexure of the seal into the space defined by the spring when an instrument penetrates the seal. In further embodiments, the cap has a secondary closure and can maintain vacuum in a container.

Abstract: A device for forming a closure, including first and second dies for cooperatively forming the closure. The dies come into mutual contact against both sides of an annular disc. The dies form a center hole and cooperatively operate to form a shoulder and skirt on the outer part of the closure. The annular center section and bridges are formed by action of a plurality of die stems which form a recessed dependent lip on the shoulder and which form frangible bridges connecting the lip to the central section.

Abstract: According to this process, the container (2) is filled, and after filling a capsule (6) carrying a valve is fixed in a sealed manner to the neck (21) of the bottle (2), said valve consisting of a membrane (5) of elastomeric material of thickness such that that valve can become sealed again by elastic recall after having undergone aspiration in order to create a reduced pressure and/or the introduction of unreactive gas, the capsule (6) and the valve (5) remaining on the container (2) and maintaining the seal of the container (2) during storage. A top cap (4) may receive the valve (5) and contribute to sealing. The invention also relates to a packaging unit for the implementation of this process.

Abstract: A container cap, comprising a cap body having an annular shoulder with an inner and outer terminal edge. The shoulder has a skirt depending from the outer terminal edge of the shoulder and an upper cylinder is attached to the annular shoulder at its inner terminal edge. The cylinder extends upward, terminating in an annular flared lip and the upper cylinder is attached to the shoulder by an annular scoring ring.

Abstract: An improved safety bottle includes a cover preferably formed of ethyl vinyl acetate, and having a cut through its top to create an integral one-way valve. The valve remains closed, securing the bottle contents against spillage and the like until opened by contact by an appropriate tool, such as a dropper or tweezers. Under such contact the valve pivots downwardly, allowing the tool to be inserted with the bottle to access the contents. When the tool is removed the valve closes, sealing the contents within the container. Both H and U-shaped cuts can be employed.

Abstract: A vial cap of plastic having a skirt portion press fit onto the neck of a vial. A transversely extending wall having a central opening is integral with the upper end portion of the skirt, and a sealing disc is positioned between the open end of the vial and the transverse wall. A plastic lid having a plastic hinge integrally connected between the lid and the skirt is provided for closing the central opening of the cap during storage. By the construction and arrangement of the plastic vial cap, the fear of aluminum toxicity is overcome and the lid prevents the accumulation of dust and other debris on the sealing disc while the vial is in storage.

Abstract: A closure for a vial or the like includes a cap clampingly engaging the rim of the vial with a resilient stopper therebetween. During the assembly of the closure, an initially one-piece cap device having an uppermost outer sleeve affixed to an integral cap provided with an outwardly flared skirt, is pressed downwardly toward the stopper disposed atop the vial rim. Continued pressure fractures the sleeve from the cap and urges the sleeve downwardly to bias the resilient skirt inwardly, causing lips thereon into a captive position beneath the vial rim. Continued downward movement of the sleeve results in a locking ring on the interior of the sleeve becoming snap-fitted within a recess in the cap skirt. An aseptic condition of the vial contents is maintained as the stopper remains under vertical compression by the top wall of the cap and in view of an annular ring on the cap top wall which is urged into a circular slot provided in the rim of the stopper, overlying the vial rim.

Abstract: A closure device for use with a container, comprising cap means with a pull tab and scoring to remove the cap, the scoring including stepped scoring on both sides of the cap with each scoring having a frangible interruption proximate the top radial edge of the cap.

Abstract: A sealing cap of metallic material, particularly for antibiotic, infusion and transfusion bottles, provided with a hole (7) on its upper wall (5), tightly closed by a metallic foil (8) substantially covering the whole wall (5) and provided with a knurled grip tongue (10) that does not project beyond the outline of the cap (2).

Abstract: A can sealing organization including an elongate central web with a downwardly depending skirt formed about a matrix of cylindrical beverage containers. The beverage containers each include an individual cap member heat sealed in a surrounding relationship to each upper end of each can, wherein each cap is integrally formed to the central web. Additionally, each cap member includes an antiseptically saturated sponge member mounted between an upper surface of the can and the cap captured therebetween, wherein each sponge member may further be formed of a doughnut-like configuration defining a central cylindrical opening containing a rupturable anti-bacterial fluid contained therewithin.