Abstract: The neck opening of a filled plastic bottle is sealed by a sealing unit ultrasonically welded to the top of the neck. The sealing unit can be a one-piece member having an upwardly projecting hollow portion arranged to be broken off to provide an opening for dispensing the contents of the bottle. Alternatively, the sealing unit can be composed of an inner cap, an outer cap and a sealing disc interposed between the caps, this unit being arranged to be pierced by a cannula for withdrawing the contents of the bottle.

Abstract: An easy tear-open or breakaway port for a container wherein the breakaway line is provided by a preweakened portion having a reduced wall section with the width varying in a uniform and progressive manner from a minimum width to a maximum one. The breakaway feature is readily adaptable to plastic containers and can be utilized in conjunction with a handle or gripping member to facilitate the tearing along the preweakened portion.

Abstract: A closure member for pierceable access ports of flexible containers of the type adapted for effective safe storage and use of parenteral fluids and similar sterile solutions, the access port having a pierceable access closure diaphragm, wherein the closure member includes a base portion in sealed engagement over the neck of the access port on the container, with a rigidifying and strengthening portion or an insert in sealed engagement therebetween, and a free-standing portion extending from the base portion and having a sealed end, the free-standing portion being connected to the base portion by a fragible thinned material section adapted to be ruptured to permit the free-standing portion to be removed, thereby providing access to the pierceable diaphragm for insertion therethrough of a parenteral solution administration spike.

Abstract: There is disclosed herein a method for blow molding a bottle, for instance, from a tube of thermoplastic material. The method includes filling such a container, if desired, with a fluid prior to sealing of the bottle. The bottle has at least one orifice which may be sealed with an integral membrane and a further protective cap is integrally molded with the bottle. Apparatus is also disclosed for molding, filling and sealing such bottles in one operation from a tube a thermoplastic material which has relatively movable mold parts.