With Ultraviolet Source Patents (Class 250/461.1)
  • Publication number: 20100213376
    Abstract: A method and a portable device for assessing the occurrence of an agent in a sample. A sample is illuminated with photons emanating from a portable device to produce photons reflected, emitted, or absorbed from a set of multiple points in the sample having a defined geometric relationship. The portable device is used to simultaneously illuminate the sample and analyze the photons reflected, emitted, or absorbed from the set of multiple points using spectroscopic methods, including infrared, fluorescence, and UV/visible. The agent assessed may include a hazardous agent, a chemical agent, a biological agent, a microorganism, a bacterium, a protozoan, a virus, and combinations thereof.
    Type: Application
    Filed: March 9, 2010
    Publication date: August 26, 2010
    Applicant: ChemImage Corporation
    Inventors: Charles W. Gardner, JR., Patrick Treado, Matthew Nelson, Robert Schweitzer
  • Patent number: 7781749
    Abstract: An illumination beam irradiation apparatus for use in pattern inspection systems is disclosed, which is less in deterioration of optical components and in attenuation of illumination light. The illumination apparatus includes a light source which yields a fundamental wave, a beam-shaper unit which performs beam-shaping of the fundamental wave so that this wave has a prespecified shape, and a pattern generator unit which operates, upon receipt of the beam-shaped fundamental wave, to convert this incoming wave into illumination light with a shorter wavelength to thereby generate illumination light of a prespecified shape. The illuminator also includes an image relay unit for guiding the illumination light that was generated by the pattern generator to fall onto a workpiece under inspection, such as a photomask or else.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: August 24, 2010
    Assignee: Advanced Mask Inspection Technology, Inc.
    Inventor: Shinichi Imai
  • Publication number: 20100187441
    Abstract: An adaptor is designed as an accessory to an ultraviolet transilluminator for the excitation of fluorescent molecules or labels in a planar array of biochemical samples such as a two-dimensional electrophoresis gel to enable the emissions resulting from the excitation to be detected and quantified. The adaptor is constructed to overlay the transilluminator and contains both a fluorescent dye that upon excitation by ultraviolet light emits light in the visible spectrum, and a conditioning substance that selects a portion of the wavelength band of the visible light produced by the fluorescent dye. The adaptor converts the ultraviolet light from the transilluminator to visible light while limiting the emissions reaching the detector to those that emanate from the sample. By the use of this adaptor, the transilluminator is adapted for use with samples labeled with dyes that are excitable by visible light and avoids exposure of the samples and the user to ultraviolet light.
    Type: Application
    Filed: January 26, 2010
    Publication date: July 29, 2010
    Applicant: BIO-RAD LABORATORIES, INC.
    Inventors: David E. Waldbeser, Neeraj Bhatt, Kevin A. McDonald
  • Publication number: 20100182590
    Abstract: A measuring device for quantitative determination of optical characteristic values for detecting photo- and/or electrochemical decomposition reactions taking place on surfaces of photocatalytically active substrates.
    Type: Application
    Filed: June 25, 2007
    Publication date: July 22, 2010
    Applicant: Fraunhofer-Gesellschaft zur Fordenrung der angewandten Forschung e.V.
    Inventors: Frank Neumann, Thomas Neubert, Michael Vergöhl
  • Publication number: 20100168907
    Abstract: A method, apparatus and system for sorting contaminated glass from a stream of glass particles used light of a wavelength suited to inducing fluorescence in the contaminated glass pieces. Automatic cleaning mechanisms are included in some embodiments to facilitate removal of coatings which would prevent the contaminated particles from fluorescing. The identified particles are then automatically separated from the remaining particles.
    Type: Application
    Filed: December 29, 2009
    Publication date: July 1, 2010
    Inventor: Thomas A. Valerio
  • Patent number: 7741608
    Abstract: In an image reader, if a first and second light sources alternately light-up when a conveying unit conveys an imaging target medium, a visible light data group that is based on a reflected light, of a wavelength inside a visible spectrum, of a first light having a wavelength inside the visible spectrum and a visible light external data group that is based on the reflected light, of the wavelength inside the visible spectrum, of a second light having a wavelength outside the visible spectrum are alternately generated. By scanning the imaging target medium once and by collecting multiple visible light data group, first image data of the imaging target medium, based on the first light, is generated. Furthermore, by collecting multiple visible light external data group, second image data of the imaging target medium, based on the second light, is also generated.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: June 22, 2010
    Assignee: PFU Limited
    Inventor: Masanari Takabatake
  • Patent number: 7741622
    Abstract: The present invention presents an exposure device, which includes an optical source for emitting a UV ray, a lighting system for shaping the UV ray into a collimated light beam, an aperture member for producing rectangular first and second light beams based on the light beam from lighting system by using the first and second rectangular windows, first and second spatial light modulators for spatially modulating the first and second light beams, respectively, and first and second projection lighting systems for guiding the modulated first and second light beams to the object.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: June 22, 2010
    Assignee: ORC Manufacturing Co., Ltd.
    Inventors: Duk Lee, Jun Ishikawa
  • Publication number: 20100148073
    Abstract: The disclosure relates generally to methods and apparatus for using telescope optics and a fiber array spectral translator-based (“FAST”) spectroscopic system for improved imaging, spectral analysis, and interactive probing of a sample. In an embodiment, the confocality of a fiber array spectral translator-based spectroscopic system is improved through the use of structured illumination and/or structured collection of photons. User input may be received and acted upon to allow a user to interactively in real time and/or near real time view and analyze specific regions of the sample.
    Type: Application
    Filed: December 7, 2009
    Publication date: June 17, 2010
    Applicant: Chemimage Corporation
    Inventors: Matthew P. Nelson, Patrick J. Treado
  • Publication number: 20100148091
    Abstract: A system for use in analyzing a pharmaceutical composition having multiple constituents comprising a luminescence sensor, the sensor being adapted to direct a plurality of radiation pulses to the pharmaceutical composition and detect luminescence emitted from each composition constituent as a function of time, the sensor being further adapted to provide at least one luminescence signal corresponding to the detected luminescence of each constituent, and control means in communication with the sensor for controlling the sensor and analyzing the luminescence signal.
    Type: Application
    Filed: September 12, 2007
    Publication date: June 17, 2010
    Inventor: Dwight Sherod Walker
  • Publication number: 20100102250
    Abstract: A phosphor (photo-luminescent) material based authentication system in which a blend (mixture) of at least two, preferably three or more, phosphor materials are used as a photo-luminescent security marking which is applied to or incorporated within an article/document to be authenticated. Preferably, the phosphor materials are each excitable by “eye safe” excitation radiation comprising visible light of wavelength 380 nm to 780 nm. Moreover, when excited the security marking preferably also emits visible light thereby minimizing any risk of damage to an operator's eye in the event of accidental exposure to the excitation radiation and/or light generated by the photo-luminescent marking. The authenticity of the article/document can be authenticated by verification of the composition of the phosphor by exciting the marking and comparing one or more selected parameters of light emitted by the security marking with corresponding parameters of the characteristic emission spectrum of the authentic phosphor blend.
    Type: Application
    Filed: October 22, 2009
    Publication date: April 29, 2010
    Applicant: INTEMATIX CORPORATION
    Inventors: Yi-Qun Li, Haitao Yang
  • Patent number: 7700929
    Abstract: A system for detecting atmospheric contamination, the system comprising a laser operable to generate an infrared light beam comprising a longitudinal component and a transverse component, the laser remote from the atmospheric contamination, and a processor operable to process a flouresence resulting from contact between the atmospheric contamination and an ultraviolet light being generated from the longitudinal and transverse components of the infrared light of the laser, wherein the processor determines the identity of the fluorescence by comparing the fluorescence to known fluorescence.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: April 20, 2010
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Antonio Ting, Ilya Alexeev, Phillip Sprangle, Richard Hubbard, Glenn Rubel, Eldridge Briscoe, Christopher Moore
  • Publication number: 20100084572
    Abstract: An ultraviolet (UV) fluorometric sensor measures a chemical concentration in a sample based on the measured fluorescence of the sample. The sensor includes a controller, at least one UV light source, and at least one UV detector. The sensor emits UV light in a wavelength range of 245-265 nm from the light source through the sample in an analytical area. The UV detector measures the fluorescence emission from the sample. The controller transforms output signals from the UV detector into fluorescence values or optical densities for one or more wavelengths in the wavelength range of 265-340 nm. The controller calculates the chemical concentration of the chemical in the sample based on the measured fluorescence emissions.
    Type: Application
    Filed: December 8, 2009
    Publication date: April 8, 2010
    Applicant: Ecolab Inc.
    Inventors: Eugene Tokhtuev, Christopher J. Owen, Viktor Slobodyan, Anatoly Skirda, Paul Schilling, Anna Pilipchenko, Paul R. Kraus, Katherine M. Sanville, Joseph Phillip Erickson
  • Patent number: 7692172
    Abstract: A system for sanitizing an enclosed structure comprises a first sensor, a second sensor, a third sensor, a germicidal ultraviolet light source, a motor, and a controller. The first sensor detects the presence of humans or animals within the enclosed structure. The second sensor detects the position of at least one door of the enclosed structure. The third sensor detects tampering with the system. The ultraviolet light source provides electromagnetic radiation in the ultraviolet range. The motor moves the ultraviolet light source from an inactive position to an active position and from the active position to the inactive position. The controller receives inputs from the first sensor, the second sensor, and the third sensor, and transmits outputs to the ultraviolet light source and the motor.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: April 6, 2010
    Assignee: Sound Health Designs, LLC
    Inventor: David Leben
  • Patent number: 7683355
    Abstract: An EUV light source apparatus capable of preventing the efficiency of generation of EUV light from decreasing due to deterioration of a window of an EUV light generation chamber. The EUV light source apparatus includes an EUV light generation chamber provided with a window, a driver laser which generates a laser beam, a concave lens which enlarges the laser beam, a convex lens which collimates the enlarged laser beam, a parabolic concave mirror which is arranged in the EUV light generation chamber and reflects the collimated laser beam to collect the laser beam to a target material, a parabolic concave mirror adjusting mechanism which adjusts position and angle of the parabolic concave mirror, an EUV light collector mirror which collects EUV light, and a purge gas supply unit which supplies a purge gas for protecting the window and the parabolic concave mirror.
    Type: Grant
    Filed: September 24, 2007
    Date of Patent: March 23, 2010
    Assignee: Komatsu Ltd.
    Inventors: Masato Moriya, Tamotsu Abe, Takashi Suganuma, Hiroshi Someya, Takayuki Yabu, Akira Sumitani
  • Patent number: 7683346
    Abstract: A method used to detect and identify biological substances suspended in air in the form of aerosols or clouds including generating a remote infrared light beam directed toward the atmospheric contamination, producing an ultraviolet light beam from the infrared light beam by compression via the air through which the IR beam travels, and producing fluorescence of the atmospheric contamination, when the generated ultraviolet light contacts the atmospheric contamination. The fluorescent signals are then processed in order to identify the nature of the atmospheric contamination.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: March 23, 2010
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Antonio C Ting, Ilya Alexeev, Phillip A Sprangle, Richard F Hubbard, Glenn Rubel, Eldridge C Briscoe, Christopher I Moore
  • Patent number: 7675021
    Abstract: A two-dimensional image sensor is disclosed. The image sensor includes an array of photodetectors directed towards a first side. Emitters directed towards the first side are also provided, with the emitters emitting infrared light when illuminated by ultraviolet light. An ultraviolet light source is provided for illuminating the emitters, and a filter prevents ultraviolet light from illuminating the photodetectors.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: March 9, 2010
    Assignee: Silverbrook Research Pty Ltd
    Inventor: Paul Lapstun
  • Patent number: 7667217
    Abstract: An apparatus for easily shooting an invisible image (such as an invisible two-dimensional bar code) latent on an object. The operation of the apparatus is made intuitive and simple and may be incorporated into cameras peripheral to computers and mobile telephones. A novel framing and focusing system is also disclosed.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: February 23, 2010
    Assignee: International Business Machines Corporation
    Inventors: Noboru Kamijoh, Toshitaka Imai, Kazumasa Ochiai, Konichi Kamijoh
  • Publication number: 20100032584
    Abstract: An apparatus (10) for detecting a particle (12) labelled with a fluorescent marker is disclosed. The apparatus (10) has a flow cell (16) being adapted to contain a fluid (14) in which the particle (12) is suspended. A light source (28) is operatively coupled to the flow cell (16) and arranged for emitting a stimulating light (28) which is effective in optically exciting the fluorescent marker (12) for emitting a fluorescent light (30). The apparatus (10) also includes a spatial filter (50) across an optical path between the particle (12) and a time gated detector (32) operatively coupled to the flow cell (16) for detecting the fluorescent light (30).
    Type: Application
    Filed: August 17, 2007
    Publication date: February 11, 2010
    Applicant: MACQUARIE UNIVERSITY
    Inventors: Jin Dayong, Jim Piper, Russell Connally
  • Patent number: 7652267
    Abstract: An ultraviolet (UV) fluorometric sensor measures a chemical concentration in a sample based on the measured fluorescence of the sample. The sensor includes a controller, at least one UV light source, and at least one UV detector. The sensor emits UV light in a wavelength range of 245-265 nm from the light source through the sample in an analytical area. The UV detector measures the fluorescence emission from the sample. The controller transforms output signals from the UV detector into fluorescence values or optical densities for one or more wavelengths in the wavelength range of 265-340 nm. The controller calculates the chemical concentration of the chemical in the sample based on the measured fluorescence emissions.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: January 26, 2010
    Assignee: Ecolab Inc.
    Inventors: Eugene T. Tokhtuev, Christopher J. Owen, Viktor Slobodyan, Anatoly Skirda, Paul Schilling, Anna Pilipchenko, Paul R. Kraus, Katherine M. Sanville, Joseph Phillip Erickson
  • Patent number: 7649186
    Abstract: In an EUV focusing mirror in which there are several thin concave nested high precision mirrors in the form of an ellipsoid of revolution, a paraboloid of revolution, a Wolter type or the like, the sides which do not constitute the reflection surfaces are made in the shape of a knife edge at the radiation incident ends of the respective mirrors in order not to be shielded by the thickness of the radiation incidence sides of the respective mirrors. Likewise, the radiation exit ends of the respective mirrors are made in the form of a knife edge. This yields an advantageous far-field distribution use of the mirrors for an EUV radiation source device and the degree of reduction of the light intensity can be made smaller than in the conventional case.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: January 19, 2010
    Assignee: Ushiodenki Kabushiki Kaisha
    Inventors: Kiyoyuki Kabuki, Hiroto Sato
  • Patent number: 7649684
    Abstract: An optical apparatus minimizes autofluorescence and stray light as well as leakage of excitation light and efficiently utilizes illuminating light from a fluorescence illumination optical system to allow observation of a bright fluorescence image. An observation apparatus has an objective, an observation optical system unit including a variable magnification optical system, and an imaging optical system unit including an imaging lens and an eyepiece. A fluorescence illumination apparatus, which is provided separately, is removably attached to the observation apparatus. The fluorescence illumination apparatus has a light source, a collector lens unit, and a reflecting member placed between the objective and the observation optical system unit at a position displaced from the optical axis of the objective to make light from the light source incident on the objective. An excitation filter is provided between the light source and the reflecting member.
    Type: Grant
    Filed: June 8, 2005
    Date of Patent: January 19, 2010
    Assignee: Olympus Corporation
    Inventors: Kenji Kawasaki, Daisuke Nishiwaki, Keiji Shimizu
  • Publication number: 20100006775
    Abstract: A phosphor for use, for example, with an ultraviolet LED to provide a broad-spectrum white light approximating diffuse sunlight, that includes quantum dots spaced from an activator material by a capping layer surrounding the quantum dots. This approach of spacing an activator material from the quantum dots provides improved spectral output for quantum dots of materials such as zinc sulfide.
    Type: Application
    Filed: July 14, 2009
    Publication date: January 14, 2010
    Inventor: Charles Phillip Gibson
  • Patent number: 7646001
    Abstract: A device for the identification of security features on an identification card, wherein the device includes a housing having a pair of circuit boards, a pair of light-emitting diodes and a magnification apparatus to allow for operation during both daylight and darkness.
    Type: Grant
    Filed: March 12, 2008
    Date of Patent: January 12, 2010
    Inventor: David Michael Feyler
  • Patent number: 7646002
    Abstract: A fluorescence detecting system includes a stimulating light projector which projects onto an object part which has been dosed with a fluorescence agent first stimulating light in the exciting wavelength range of the fluorescence agent and second stimulating light which differs from the first stimulating light in the wavelength band and is in the exciting wavelength range of the auto-fluorescence material contained in the object part, and a fluorescence information obtainer which obtains the fluorescence from the fluorescence agent information based on the fluorescence from the fluorescence agent emitted from the object part in response to projection of the first stimulating light and the auto-fluorescence information based on the auto-fluorescence emitted from the object part in response to projection of the second stimulating light. The fluorescence agent is a fluorescence agent which does not emit fluorescence in response to projection of the second stimulating light.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: January 12, 2010
    Assignee: FUJIFILM Corporation
    Inventor: Tomonari Sendai
  • Publication number: 20100002194
    Abstract: A projecting device includes a light source, a filtering component, a reflecting mirror, a digital micro-mirror device, a projecting lens, and a panel. The filtering component changes lights emitted from the light source into substantially parallel polarized ultraviolet lights. The reflecting mirror reflects the substantially parallel polarized ultraviolet lights to the digital micro-mirror device. The digital micro-mirror device includes microscopic mirrors arranged in a rectangular array configured to be adjustable to reflect the substantially parallel polarized ultraviolet lights reflected by the reflecting mirror to the projecting lens. The projecting lens diverges the substantially parallel polarized ultraviolet lights. The panel includes a transparent substrate, a first fluorescence material layer, a second fluorescence material layer, and a third fluorescence material layer.
    Type: Application
    Filed: December 31, 2008
    Publication date: January 7, 2010
    Applicant: HON HAI PRECISION INDUSTRY CO., LTD.
    Inventor: Ga-Lane Chen
  • Publication number: 20100001210
    Abstract: A luminescence sensor, comprising a non-transparent substrate structure (2) having at least one aperture (5) intended to comprise an analyte and a transparent substrate structure (3), which is arranged to or adjacent said first structure (2). The aperture has a smallest lateral dimension, which is smaller than half the effective wavelength of an excitation radiation, such as light at a wavelength of 700 nm, resulting in an effective wavelength in water of about 538 nm. The transparent structure has a trench (4) with a surface portion provided with ligands with an affinity towards a target molecule. The trench results in that a luminophore attached to the target molecule will be positioned at the entrance surface of the aperture, where the excitation energy is largest.
    Type: Application
    Filed: December 17, 2007
    Publication date: January 7, 2010
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Derk J.W. Klunder, Maarten M.J.W. Van Herpen, Hendrik R. Stapert
  • Patent number: 7642524
    Abstract: A sanitizing apparatus for writing utensils comprising a housing assembly and an ultraviolet and ozone generating assembly housed therein. The housing assembly comprises a top wall, a base and four walls. The first and second walls are perpendicularly disposed with respect to the third and fourth walls. The third and fourth walls are lateral walls. The housing assembly also comprises an angled wall that protrudes outwardly beyond the top wall and beyond the first wall defining a tray that terminates with a lip for preventing the writing utensil from falling off. A battery compartment is also housed within the housing assembly. The ultraviolet and ozone generating assembly radiates the writing utensil within the housing assembly with rays and ozone, to effectively sterilize bacteria and biological germs existing on the writing utensil. A visual indicator notifies a user when the ultraviolet and ozone generating assembly is operating.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: January 5, 2010
    Inventors: Lazaro F. Alvarez, Jorge Dierksmeier, Howard J. Rubin, Allan Afrow
  • Patent number: 7638778
    Abstract: A sterilization device includes a shell, an ultraviolet ray lamp tube fixed with a lamp support on an upper end of the shell, an inner quartz tube around the lamp tube, an outer quartz tube around the inner quartz tube, a stainless steel tube around the outer quartz tube, an inner passage between the inner and the outer quartz tubes, an outer passage between the outer quartz tube and the stainless steel tube, and a guiding member on the lower end of the shell; the guiding member has guiding holes to guide water along a spiral path, and a water inlet on a lower portion thereof, which communicates with the guiding holes; a covering member is threadedly engaged with an outer side of the lower end of the shell; the water inlet of the guiding member extends through the covering member; the covering member has a water outlet hole.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: December 29, 2009
    Inventor: Mei-Lan Chen
  • Patent number: 7635588
    Abstract: An apparatus and method are provided for differentiating multiple detectable signals by excitation wavelength. The apparatus can include a light source that can emit respective excitation light wavelengths or wavelength ranges towards a sample in a sample retaining region, for example, in a well. The sample can contain two or more detectable markers, for example, fluorescent dyes, each of which can be capable of generating increased detectable emissions when excited in the presence of a target component. The detectable markers can have excitation wavelength ranges and/or emission wavelength ranges that overlap with the ranges of the other detectable markers. A detector can be arranged for detecting an emission wavelength or wavelength range emitted from a first marker within the overlapping wavelength range of at least one of the other markers.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: December 22, 2009
    Assignee: Applied Biosystems, LLC
    Inventors: Howard G. King, Steven J. Boege, Eugene F. Young, Mark F. Oldham
  • Publication number: 20090302236
    Abstract: A light emitting device comprising a light producing element configured to generate ultraviolet light having a wavelength of from about 250 nm to about 400 nm and a self-activating phosphor comprising an ordered oxyfluoride compound is provided. The nitrogen-free or nitrogen-containing ordered oxyfluoride compound has a formula: A3-3a/2RaMO4-?1-w?F1-?2-w—Nw where A is Sr alone or Sr mixed with Ba and/or Ca such that A comprises at least about ? mole % of Sr and up to about ? mole percent of Ba and/or Ca; R is a rare earth element or a mixture of rare earth elements; M is Al, Ga, In, W, Mo, Bi, or mixtures thereof; 0<a?0.3; ?1 and ?2 are both from about 0.01 to about 0.1; and 0?w?0.05 such that 0?w??0.1 and 0?w??0.15. The ultraviolet light excites the self-activating phosphor such that the self-activating phosphor emits visible light having a wavelength of from about 380 to about 750 nm.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 10, 2009
    Applicant: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Thomas Vogt, Sangmoon Park
  • Publication number: 20090296085
    Abstract: A system and method for full width scanning color analysis of a printed media sheet are disclosed. The full width array spectrophotometer system includes one or more substantially linear elongated illumination arrays of closely spaced multiple illumination sources. The sources include sets of illumination sources, including a first set of different color illumination sources and a second set including one or more UV-emitting illumination sources. The sets are arranged to span a printer paper path or other object path to illuminate a band extending transversely across a printed print media sheet or other object moving in the path. A full width array light imaging sensor includes an elongated array of multiple closely spaced photodetectors for detecting plural colors and is positioned adjacent to and extending substantially parallel to the linear array(s) to receive radiation reflected from the transverse illuminated band.
    Type: Application
    Filed: August 20, 2008
    Publication date: December 3, 2009
    Applicant: Xerox Corporation
    Inventor: Lalit Keshav Mestha
  • Publication number: 20090294692
    Abstract: A method and a system for producing a change in a medium disposed in an artificial container. The method places in a vicinity of the medium at least one of a plasmonics agent and an energy modulation agent. The method applies an initiation energy through the artificial container to the medium. The initiation energy interacts with the plasmonics agent or the energy modulation agent to directly or indirectly produce the change in the medium. The system includes an initiation energy source configured to apply an initiation energy to the medium to activate the plasmonics agent or the energy modulation agent.
    Type: Application
    Filed: March 10, 2009
    Publication date: December 3, 2009
    Applicants: Duke University, Immunolight, LLC
    Inventors: Frederic Avery Bourke, JR., Tuan Vo-Dinh
  • Publication number: 20090294691
    Abstract: The invention concerns the use of the fluorescence polarization phenomenon to improve detection of fluorescent signals during a fluorescence resonance energy transfer (FRET). In particular, the invention concerns a method for improving signal/noise ratio in a FRET measurement. The invention also concerns an apparatus for measuring fluorescence following an energy transfer between a donor fluorescent compound and an acceptor fluorescence compound in a measurement medium.
    Type: Application
    Filed: June 27, 2005
    Publication date: December 3, 2009
    Applicant: CIS BIO INTERNATIONAL
    Inventors: Eric Trinquet, Gerard Mathis
  • Publication number: 20090294694
    Abstract: The invention is directed to a resolution-enhanced luminescence microscopy method in which a sample is excited to the emission of luminescence radiation through irradiation by excitation radiation, and an image of the luminescing sample is acquired. A first partial volume of the sample is irradiated by a first laser radiation field of the excitation radiation, and a second partial volume of the sample is irradiated by a second laser radiation field of the excitation radiation. The first partial volume of the sample and the second partial volume of the sample overlap one another partially but not completely. Only the first laser radiation field is modulated with a first frequency, and luminescence radiation is detected from the first partial volume of the sample with modulation filtering so that luminescence radiation from the second partial volume of the sample is suppressed.
    Type: Application
    Filed: September 10, 2007
    Publication date: December 3, 2009
    Inventor: Helmut Lippert
  • Patent number: 7612353
    Abstract: A lithographic apparatus includes a radiation system including a radiation source for the production of a radiation beam, and a contaminant trap arranged in a path of the radiation beam. The contaminant trap includes a plurality of foils or plates defining channels that are arranged substantially parallel to the direction of propagation of said radiation beam. The foils or plates can be oriented substantially radially with respect to an optical axis of the radiation beam. The contaminant trap can be provided with a gas injector which is configured to inject gas at least at two different positions directly into at least one of the channels of the contaminant trap.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: November 3, 2009
    Assignee: ASML Netherlands B.V.
    Inventors: Leonid Aizikovitch Sjmaenok, Vadim Yevgenyevich Banine, Josephus Jacobus Smits, Lambertus Adrianus Van Den Wildenberg, Alexander Alexandrovitch Schmidt, Arnoud Cornelis Wassink, Eric Louis Willem Verpalen, Antonius Johannes Van De Pas, Paul Peter Anna Antonius Brom
  • Patent number: 7612349
    Abstract: Exciting light is irradiated through a dielectric material block toward an interface between the dielectric material block and a metal film formed on one surface of the dielectric material block, such that total reflection conditions may be satisfied. An intensity of analysis fluorescence produced by an analysis fluorescent substance, which is contained in a sample and produces the analysis fluorescence by being excited by an evanescent wave oozing out from the interface when the exciting light impinges upon the interface, is normalized in accordance with an intensity of reference fluorescence produced by a reference fluorescent substance, which has been located at a position for excitation by the exciting light.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: November 3, 2009
    Assignee: FUJIFILM Corporation
    Inventor: Toshihito Kimura
  • Patent number: 7608841
    Abstract: A system and method for fluorescence excitation and detection having distinct optical paths is disclosed. A system for detecting fluorescence comprises a light source that emits an excitation light into an illumination tube; a plurality of collection optics located around an aperture in the illumination tube for collecting fluorescence; and a detector for determining the amount of fluorescence. A method for detecting fluorescence comprises emitting an excitation light from a light source into an illumination tube; directing the excitation light to an excitation filter; illuminating a sample with the excitation light to generate an emission light; and detecting the optical characteristics of the emission light using a plurality of collection optics located around the illumination tube.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: October 27, 2009
    Assignee: Stratagene California
    Inventors: Taylor A. Reid, Roger H. Taylor, Kenneth J. Zajac
  • Publication number: 20090262334
    Abstract: A system according to one embodiment includes a light source for generating light fringes; a sampling mechanism for directing a particle through the light fringes; and at least one light detector for detecting light scattered by the particle as the particle passes through the light fringes. A method according to one embodiment includes generating light fringes using a light source; directing a particle through the light fringes; and detecting light scattered by the particle as the particle passes through the light fringes using at least one light detector.
    Type: Application
    Filed: December 15, 2008
    Publication date: October 22, 2009
    Inventor: Paul T. Steele
  • Patent number: 7605920
    Abstract: Disclosed herein is a method of identifying a unidentified substance, comprising directing light from a light emitting source directly upon a stationary unidentified substance; collecting fluorescence from the unidentified substance in a detector; wherein the detector comprises a lock-in detection system; analyzing the fluorescence; and identifying the unidentified substance. Disclosed herein is a detection system comprising a light emitting source; a circuit board; wherein the trigger is operative to trigger a pulse of electrons from the circuit board to the light emitting source; a detector; and a central processing unit, wherein fluorescence generated from an unknown unidentified substance that is illuminated by light from the light emitting source is collected in the detector and analyzed in the central processing unit.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: October 20, 2009
    Assignee: GE Homeland Protection, Inc.
    Inventors: Steven Francis LeBoeuf, Alexei Vasilievich Vertiatchikh, Rui Chen, Radislav Alexandrovich Potyrailo
  • Patent number: 7601960
    Abstract: A UV light source water disinfection system includes a UV light source that is driven or controlled by a ballast. Improved start-up scenarios are provided by use of a separate heating wire around the lamp or employing an inductive-coupled system to provide initial high power requirements. The UV lamp is discontinuously operated in order to extend the life of the system, save energy, and periodically dose standing water to prevent regeneration of undesired microorganisms.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: October 13, 2009
    Assignee: General Electric Company
    Inventors: Andy Albrecht, Larry Fish, Sam DuPlessis, Timothy E. Chen
  • Publication number: 20090242800
    Abstract: An electron-beam dimension measuring apparatus includes: electron-beam irradiating means for irradiating a surface of a sample with an electron beam; a stage on which the sample is placed; a photoelectron generating electrode disposed so as to face the sample; ultraviolet light irradiating means for emitting ultraviolet light; and control means for causing the ultraviolet light irradiating means to irradiate the sample and the photoelectron generating electrode with the ultraviolet light for a predetermined length of time, to cause the sample and the photoelectron generating electrode to emit photoelectrons, for applying a voltage to the photoelectron generating electrode, the voltage applied to supply energy corresponding to a difference between energy of photoelectrons emitted by the sample and energy of photoelectrons emitted by the photoelectron generating electrode, and thereby for controlling an electric potential of the surface of the sample to set the electric potential at 0 V.
    Type: Application
    Filed: March 5, 2009
    Publication date: October 1, 2009
    Inventor: Masayuki Kuribara
  • Publication number: 20090242803
    Abstract: An optical property measuring method and an optical property measuring apparatus according to an aspect of the invention are operable to select bi-spectral characteristics relatively close to bi-spectral characteristics of a fluorescent sample, out of multiple bi-spectral characteristics stored in advance, based on a relative ratio between excitation efficiencies of the fluorescent sample illuminated by excitation illuminations whose spectral distributions are different from each other, in calculating an optical property of the fluorescent sample. The inventive optical property measuring method and optical property measuring apparatus are advantageous in calculating an optical property of a fluorescent sample easily and with high precision.
    Type: Application
    Filed: March 18, 2009
    Publication date: October 1, 2009
    Inventor: Kenji Imura
  • Publication number: 20090242804
    Abstract: The present invention aims at reducing background noise derived from a substance that is present in the vicinity of a target substance such as a DNA and protein and attached to the surface of a substrate without an effect on a fluorescent dye labeling the target substance. The substrate that has a probe and is capable of interacting with the target substance is irradiated with noise removing light such that an evanescent field is generated on the surface of the substrate. A target substance and a foreign particle, which are non-specifically stuck to the surface of the substrate, are decomposed by the evanescent field generated by the irradiation with the noise removing light. The evanescent field present near the surface of the substrate has almost no effect on the probe.
    Type: Application
    Filed: March 9, 2009
    Publication date: October 1, 2009
    Inventors: Takayuki OBARA, Satoshi Takahashi, Akira Maekawa, Takuya Matsui, Nobutaka Kumazaki
  • Publication number: 20090236543
    Abstract: A method and system is provided that takes advantage of the atmospheric transmission properties of the Hydrogen Lyman-? radiation line (121.6 nm wavelength) to illuminate a sample with high energy VUV photons at least partially in an atmospheric environment. Thus, according to the principles of the present invention, a sample is illuminated by radiation at the Hydrogen Lyman-? radiation line (121.6 nm wavelength), at least partially in an atmospheric environment, and luminescent radiation from the sample at longer wavelengths is detected. The high energy illuminating photons generate luminescent radiation from the sample at longer wavelengths, typically in the visible wavelength range, and this radiation can then be imaged, e.g. with a normal visible microscope.
    Type: Application
    Filed: March 17, 2009
    Publication date: September 24, 2009
    Applicant: Nikon Corporation
    Inventors: Hiroshi Ooki, W. Thomas Novak
  • Patent number: 7592598
    Abstract: There is provided a projection objective for a projection exposure apparatus that has a primary light source for emitting electromagnetic radiation having a chief ray with a wavelength ?193 nm. The projection objective includes an object plane, a first mirror, a second mirror, a third mirror, a fourth mirror; and an image plane. The object plane, the first mirror, the second mirror, the third mirror, the fourth mirror and the image plane are arranged in a centered arrangement around a common optical axis. The first mirror, the second mirror, the third mirror, and the fourth mirror are situated between the object plane and the image plane. The chief ray, when incident on an object situated in the object plane, in a direction from the primary light source, is inclined away from the common optical axis.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: September 22, 2009
    Assignee: Carl Zeiss SMT AG
    Inventors: Hans-Juergen Mann, Wolfgang Singer, Joerg Schultz, Johannes Wangler, Karl-Heinz Schuster, Udo Dinger, Martin Antoni, Wilhelm Ulrich
  • Patent number: 7592608
    Abstract: A method includes illuminating a mixture of materials in a wet-end of a paper process, where the mixture includes an ultraviolet-activated material. The method also includes measuring light from the mixture and determining a property of the ultraviolet-activated material based on the measured light. The method may further include adjusting an operation in the wet-end of the paper process based on the determined property of the ultraviolet-activated material. The determined property could include a quantity of fluorescent material in recycled material used to form stock for a paper machine and/or a quantity of fluorescent material in stock provided to a headbox in the paper process. Adjusting the operation in the wet-end could include adjusting an amount of one or more materials used to form stock provided to the headbox, such as a fluorescent whitening agent, fixative, fluorescent fiber, fluorescent pigment, fluorescent particle, fluorescent highlight, fluorescent planchette, or fluorescent quencher.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: September 22, 2009
    Assignee: Honeywell International Inc.
    Inventors: Tarja T. Shakespeare, John F. Shakespeare
  • Publication number: 20090230321
    Abstract: A sterilization device includes a shell, an ultraviolet ray lamp tube fixed with a lamp support on an upper end of the shell, an inner quartz tube around the lamp tube, an outer quartz tube around the inner quartz tube, a stainless steel tube around the outer quartz tube, an inner passage between the inner and the outer quartz tubes, an outer passage between the outer quartz tube and the stainless steel tube, and a guiding member on the lower end of the shell; the guiding member has guiding holes to guide water along a spiral path, and a water inlet on a lower portion thereof, which communicates with the guiding holes; a covering member is threadedly engaged with an outer side of the lower end of the shell; the water inlet of the guiding member extends through the covering member; the covering member has a water outlet hole.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 17, 2009
    Inventor: Mei-Lan Chen
  • Patent number: 7589330
    Abstract: A camera obtains an observation image of a sample by capturing the image of the sample on which an ultraviolet light generated by a light source device is irradiated. An image processing unit of a controlling device generates a synthesis observation image of the sample based on a plurality of observation images of the sample, which are obtained by being captured by the camera in the same field of view with switching of the wavelength band of the ultraviolet light irradiated on the sample. A display unit of the controlling device displays the image generated by the image processing unit.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: September 15, 2009
    Assignee: Olympus Corporation
    Inventors: Go Ryu, Daisuke Yokoi, Masato Yabe
  • Patent number: 7586113
    Abstract: An illumination system is used to illuminate a specified illumination field of an object surface with EUV radiation. The illumination system has an EUV source and a collector to concentrate the EUV radiation in the direction of an optical axis. A first optical element is provided to generate secondary light sources, and a second optical element is provided at the location of these secondary light sources, the second optical element being part of an optical device which includes further optical elements, and which images the first optical element into an image plane into the illumination field. Between the collector and the illumination field, a maximum of five reflecting optical elements are arranged. These optical elements reflect the main beam either grazingly or steeply. The optical axis, projected onto an illumination main plane, is deflected by more than 30° between a source axis portion and a field axis portion.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: September 8, 2009
    Assignee: Carl Zeiss SMT AG
    Inventors: Martin Endres, Jens Ossmann
  • Publication number: 20090212236
    Abstract: An ultraviolet (UV) fluorometric sensor measures a chemical concentration in a sample based on the measured fluorescence of the sample. The sensor includes a controller, at least one UV light source, and at least one UV detector. The sensor emits UV light in a wavelength range of 245-265 nm from the light source through the sample in an analytical area. The UV detector measures the fluorescence emission from the sample. The controller transforms output signals from the UV detector into fluorescence values or optical densities for one or more wavelengths in the wavelength range of 265-340 nm. The controller calculates the chemical concentration of the chemical in the sample based on the measured fluorescence emissions.
    Type: Application
    Filed: May 6, 2009
    Publication date: August 27, 2009
    Applicant: Ecolab Inc.
    Inventors: Eugene Tokhtuev, Christopher J. Owen, Viktor Slobodyan, Anatoly Skirda, Paul Schilling, Anna Pilipchenko, Paul R. Kraus, Katherine M. Sanville, Joseph Phillip Erickson