Luminophor Irradiation Patents (Class 250/458.1)
  • Patent number: 11906420
    Abstract: This invention is capable of improving performance of a biochemical analyzer and facilitating the maintenance. A light source includes: a first LED that emits ultraviolet light and a second LED that has a light emission spectrum different from that of the first LED, the first LED and the second LED being disposed in parallel; a reflection surface that is opposite to the first LED and reflects light of the first LED; and a dichroic surface that is opposite to the second LED, reflects light of the first LED, and allows light of the second LED to penetrate.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: February 20, 2024
    Assignee: Hitachi High-Tech Corporation
    Inventors: Yoshifumi Sekiguchi, Shin Imamura, Takahiro Ando, Tomoto Kawamura, Yuya Matsuoka, Sakuichiro Adachi, Yasuhiro Keta, Eiichiro Takada
  • Patent number: 11867897
    Abstract: An insertion assisting instrument has an outer diameter dimension set to satisfy a relationship of xb?<xc? assuming that an insertion assisting instrument is projected on X-Y coordinates such that a point on a circumference where the insertion assisting instrument has a largest outer diameter (that is, a point on an outer periphery of a proximal-end-side tapered surface at a distal end) is set as an origin and the proximal-end-side tapered surface is brought into contact with an X axis, coordinates of a second point B, which is most distal from the X axis on the circumference where the insertion assisting instrument has the largest outer diameter are (xb?, yb?), and coordinates of a third point C, which is most proximal from the X axis on a circumference at the proximal end of the insertion assisting instrument, are (xc?, yc?).
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: January 9, 2024
    Assignee: Evident Corporation
    Inventor: Motoshi Ikeya
  • Patent number: 11867603
    Abstract: A mold sensor is configured with an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes an optical sensor that is configured to measure optical properties in the enclosed chamber. A controller operates the optical sensor and is programmed to detect a presence of mold growing in the chamber based on the optical properties measured by the optical sensor.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: January 9, 2024
    Assignee: Robert Bosch GmbH
    Inventors: Seow Yuen Yee, Franz Laermer, Christian Peters, Oliver Peters, Robert Duerichen, Ning Wang, Thomas Rocznik
  • Patent number: 11870847
    Abstract: Techniques are disclosed for decentralized data flow valuation and deployment in a highly distributed system. For example, a method comprises the following steps performed in a highly distributed system comprising a plurality of gateway nodes, wherein each of the plurality of gateway nodes is operatively coupled to one or more sensors that provide sensor data to the corresponding gateway node. A data flow is obtained at a given gateway node from a decentralized data storage system upon which a plurality of data flows is stored. The data flow is executed at the given gateway node, wherein the data flow is executed on sensor data obtained by the given gateway node from the corresponding one or more sensors. A data flow valuation operation is performed at the given gateway node based on the executed data flow to generate a data flow valuation result.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: January 9, 2024
    Assignee: EMC IP Holding Company LLC
    Inventor: Stephen J. Todd
  • Patent number: 11852537
    Abstract: A flow cytometry measurement system is disclosed which includes a flow chamber configured to flow particles of interest in a flow stream, one or more optical sources configured to excite the particles of interest by an excitation light activated and deactivated according to a pulse train thus causing particles of interest emitting emission light, one or more sensor packages each comprising a plurality of photodetectors configured to receive emission light from the particles of interest and, in response, provide an output voltage signal and an output current signal corresponding to photoelectron response of an incident photon on the one or more sensor packages, and a detector configured to determine successive single molecular decay of the particles of interest, generate an emission pulse associated with each incident photon on the one or more sensor packages, and count the number of emission pulses.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: December 26, 2023
    Assignee: Miftek Corporation
    Inventors: Masanobu Yamamoto, Keegan Hernandez, J. Paul Robinson, John Jaiber González Murillo
  • Patent number: 11852794
    Abstract: A high-throughput optical sectioning imaging method and imaging system. The method includes: modulating a light beam into a modulated light beam capable of being focused on a focal plane of an objective lens and being defocused on a defocusing plane of the objective lens, the modulated light beam having incompletely identical modulated intensities on the focal plane of the objective lens; imaging, in different rows of pixels, a sample under illumination of the modulated light beam to obtain sample images in the different rows of pixels; obtaining focal plane images of sample images in the different rows of pixels by demodulation of the sample images according to a demodulation algorithm. The system includes a light beam modulation module, an imaging module and a demodulation module.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: December 26, 2023
    Assignee: HUST-SUZHOU INSTITUTE FOR BRAINSMATICS
    Inventors: Qingming Luo, Jing Yuan, Qiuyuan Zhong, Rui Jin, Hui Gong
  • Patent number: 11841324
    Abstract: A method for estimating a stimulated emission depletion microscopy (STED) resolution includes generating a first frame representing a reference image from a field-of-view, the reference image having a predetermined reference resolution, and generating at least one second frame representing a STED image from the same field-of-view, the STED image having the STED resolution to be estimated. The at least one second frame is blurred by applying a convolution kernel with at least one fit parameter to the second frame. An optimal value of the at least one fit parameter of the convolution kernel is determined for which a difference between the first frame and the blurred at least one second frame is minimized. The STED resolution is estimated based on the optimal value of the at least one fit parameter and the predetermined reference resolution.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: December 12, 2023
    Assignee: LEICA MICROSYSTEMS CMS GMBH
    Inventors: Kai Walter, Lars Friedrich
  • Patent number: 11828905
    Abstract: A dual line photodiode array device encapsulates, on a photoelectric sensing element, two columns of photodiode array units having the same specification and performance; the dual line photodiode array device includes a first photodiode array unit and a second photodiode array unit that are arranged parallel to each other and is used for achieving the measurement of particle velocity. The particle velocity may be more accurately measured by means of integrating the two columns of photodiode array units on a single photosensitive element. The dual line photodiode array device may also be applied to the measurement of raindrops and sea spray droplets.
    Type: Grant
    Filed: February 11, 2018
    Date of Patent: November 28, 2023
    Assignee: INSTITUTE OF ATMOSPHERIC PHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Hengchi Lei, Jiatian Chen, Minsong Huang, Xiaoqing Zhang, Shouyin Zheng
  • Patent number: 11816274
    Abstract: The present disclosure relates to a display device, a touch input device, and a touch input system, where the display device comprises: a display unit including a plurality of light emitting areas; a plurality of touch electrodes disposed between the plurality of light emitting areas and configured to sense a touch; a plurality of grid patterns separated from the plurality of touch electrodes in a preset shape or formed integrally with the plurality of touch electrodes; and a plurality of code patterns formed in a preset code shape in some areas of a front surface corresponding to the plurality of touch electrodes, wherein the plurality of grid patterns comprise grid reference points of intersecting grid reference lines, and are respectively formed at positions corresponding to the grid reference points.
    Type: Grant
    Filed: October 4, 2022
    Date of Patent: November 14, 2023
    Assignee: SAMSUNG DISPLAY CO., LTD.
    Inventors: Gi Na Yoo, Ju Yeon Kim, Won Sang Park, Chang Woo Shim, Seong Jun Lee, Dong Hee Choi
  • Patent number: 11761896
    Abstract: An analyzing system includes a detection area with a transparent window past which an analyte moves and emits or transmits light. One or more polarizing elements receive and polarize the light into respective two or more different polarization components. One or more optical detectors receive the respective two or more polarization components and generate respective at least two signals in response. A processor is coupled to the optical detectors and configured to determine a polarization status of the light from the analyte based on the at least two signals.
    Type: Grant
    Filed: December 8, 2022
    Date of Patent: September 19, 2023
    Assignee: XEROX CORPORATION
    Inventors: Qiushu Chen, Peter Kiesel, Jacob N. Chamoun, Norman Nan Shi, Noble M. Johnson
  • Patent number: 11764032
    Abstract: Apparatuses for collection of wavelength resolved and angular resolved cathodoluminescence (WRARCL) emitted from a sample exposed to an electron beam (e-beam) or other excitation beams are described. Cathodoluminescence light (CL) may be emitted from a sample at specific angles relative to the excitation beam and analyzed with respect to light-emitting and other optical phenomena. The described embodiments allow collection of WRARCL data more efficiently and with significantly fewer aberrations than existing systems.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: September 19, 2023
    Assignee: Gatan, Inc.
    Inventors: Michael Bertilson, John Andrew Hunt, David J. Stowe
  • Patent number: 11747268
    Abstract: A method and system for authenticating an item includes irradiating the item, the item including a polymer substrate including a polymer material and a doping material and configured to emit a radiation spectrum having a spectral signature in response to the irradiating, the doping material capable of absorbing or scattering radiation at a specific wavelength to generate the spectral signature, detecting the spectral signature, and determining a code associated with the spectral signature.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: September 5, 2023
    Assignee: Spectra Systems Corporation
    Inventor: Nabil Lawandy
  • Patent number: 11710232
    Abstract: The present disclosure relates to the field of image processing and discloses an agricultural advisory system (100) comprising a user device (102) and a cloud server (104). The user device (102) captures a digital image of a scene, receives a sensed data corresponding to scene-related and environmental parameters, and transmits the image and the sensed data to the cloud server. The server (104) stores one or more pre-trained prediction models and a three-dimensional HyperIntelliStack which maps red green blue (RGB) pixel values with hyperspectral reflectance values. The server (104) receives the digital images and the sensed data, transforms the received image made of RGB pixel values into a hyperspectral image using the HyperIntelliStack data structure, computes vegetation indices for each pixel of the hyperspectral image to generate a segmented image, and generates at least one advisory for agriculture and allied areas using the segmented image and one or more prediction models.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: July 25, 2023
    Assignee: RELIANCE INDUSTRIES LIMITED
    Inventors: Rahul Badhwar, Arun Banerjee, Raghuram Lanka, Kenny Paul, Rajesh Nandru, Suraj Chavan, Sushant Kangade, Bhaskar Bhadra
  • Patent number: 11703387
    Abstract: The present invention provides a time-resolved single-photon counting apparatus, including an excitation light source for generating pulsed excitation light, a specimen optics for collecting an optical signal caused by irradiating the pulsed excitation light to a specimen, a photoelectric converter for photoelectrically converting the optical signal to generate an analog single-photon signal, an analog-to-digital (AD) signal converter for sampling the analog single-photon signal to convert the same into a digital single-photon signal, a digital photon-discrimination and timing detector for generating a photon-discrimination signal by discriminating the single-photon property of the digital single-photon signal to count a pulse time point of the digital single-photon signal to generate a delay time signal having delay time information, and a time-signal processor for counting valid single-photon detection events according to the delay time with reference to the photon-discrimination signal.
    Type: Grant
    Filed: January 20, 2020
    Date of Patent: July 18, 2023
    Assignee: KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
    Inventor: Sucbei Moon
  • Patent number: 11680905
    Abstract: A biological analysis system can include an excitation module and an emission module. The excitation module can include a collimator element for receiving excitation light from the excitation light source and transmitting collimated excitation light in a first direction, and a plurality of excitation mirrors arrayed along the excitation light path, each excitation mirror disposed at an acute angle relative to the first direction and configured to reflect collimated excitation light along a second direction. The emission module can be positioned to receive excitation light transmitted along the second direction and can include a sample block comprising a plurality of sample receptacles positioned to receive a beam of collimated excitation light, and a plurality of photodetectors configured to receive emission light transmitted from a respective sample receptacle in a direction transverse to the second direction of the excitation light path.
    Type: Grant
    Filed: January 11, 2022
    Date of Patent: June 20, 2023
    Assignees: Life Technologies Holdings PTE LTD, Life Technologies Corporation
    Inventors: Ming Song Chen, Chee Woei Chong, Wuh Ken Loh, Wern Yuh Foo, Kuan Moon Boo, Norbert Leclerc, Kristina Uhlendorf, Reiner Koellner, Torsten Fuchs, Stefan Breitfelder
  • Patent number: 11662316
    Abstract: A fluorescence observation apparatus according to an embodiment of the present technology includes a stage, an excitation section, and a spectroscopic imaging section. The stage is capable of supporting a fluorescently stained pathological specimen. The excitation section irradiates the pathological specimen on the stage with a plurality of line illuminations of different wavelengths, the plurality of line illuminations being a plurality of line illuminations situated on different axes and parallel to a certain-axis direction. The spectroscopic imaging section includes at least one imaging device capable of separately receiving pieces of fluorescence respectively excited with the plurality of line illuminations.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: May 30, 2023
    Assignee: Sony Corporation
    Inventors: Hirokazu Tatsuta, Gakuji Hashimoto, Tetsuro Kuwayama
  • Patent number: 11656447
    Abstract: A microscopy device comprises a continuous or pulsed wave laser light source; a pair of parallel mirrors configured to receive light from the light source and reflect an array of incoherent light sheets; a beam encoder (e.g., frequency modulation reticle, Hadamard basis, random modulation pattern) to segment the array of incoherent light sheets and encode each light sheet with a respective frequency in reciprocal space; a lens configured to direct the encoded light sheets towards a biological sample; and an image capturing device configured to receive a fluorescence signal from the biological sample.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: May 23, 2023
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Kevin Kin Man Tsia, Yuxuan Ren, Jianglai Wu, Andy Kam Seng Lau, Queenie Tsz Kwan Lai
  • Patent number: 11631024
    Abstract: An apparatus useful for creating and measuring states of an entangled system, comprising a pair of interacting multi-level systems, each of systems comprising a state |g>; a state |r>, and state |r*>. One or more first electromagnetic fields excite a first transition between the ground state |g> and the state |r> to create an entangled system. One or more second electromagnetic fields are tuned between the state |r> and the intermediate state |r*> so that any population of the systems in |r*> are dark to a subsequent detection of a population in the systems in |g>, providing a means to distinguish the entangled system in the state |g> and the entangled system in the state |r>. In one or more examples, the systems comprise neutral Rydberg atoms.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: April 18, 2023
    Assignee: California Institute of Technology
    Inventors: Manuel Endres, Alexandre Cooper-Roy, Jacob P. Covey, Ivaylo S. Madjarov, Adam L. Shaw, Vladimir Schkolnik, Jason R. Williams, Joonhee Choi
  • Patent number: 11624651
    Abstract: A spectrometer comprises a plurality of isolated optical channels comprising a plurality of isolated optical paths. The isolated optical paths decrease cross-talk among the optical paths and allow the spectrometer to have a decreased length with increased resolution. In many embodiments, the isolated optical paths comprise isolated parallel optical paths that allow the length of the device to be decreased substantially. In many embodiments, each isolated optical path extends from a filter of a filter array, through a lens of a lens array, through a channel of a support array, to a region of a sensor array. Each region of the sensor array comprises a plurality of sensor elements in which a location of the sensor element corresponds to the wavelength of light received based on an angle of light received at the location, the focal length of the lens and the central wavelength of the filter.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: April 11, 2023
    Assignee: VERIFOOD, LTD.
    Inventors: Damian Goldring, Dror Sharon, Guy Brodetzki, Amit Ruf, Menahem Kaplan, Sagee Rosen, Omer Keilaf, Uri Kinrot, Kai Engelhardt, Ittai Nir
  • Patent number: 11599999
    Abstract: An apparatus, system, and method for fluorescence imaging with stray light reduction is described. The system including a light source to provide a first illumination of a scene to induce fluorescence from the scene, an image sensor to capture a fluorescence image of the scene during the first illumination, and a controller coupled to the light source, the image sensor, and memory that includes instructions that when executed by the controller causes the system to perform operations. The operations including comparing a first color channel value to a second color channel value of a given pixel included in the fluorescence image to identify one or more pixels of the fluorescence image as being affected by stray light. The operations further including generating a stray light image mask based, at least in part, on the one or more pixels of the fluorescence image identified as being affected by the stray light.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: March 7, 2023
    Assignee: Verily Life Sciences LLC
    Inventors: Brian Anderson, Tamara Troy
  • Patent number: 11575442
    Abstract: A plastic optical fiber communication system includes a light source that emits a first signal having a first wavelength in a visible light spectrum, the first signal being encoded with information at a high data-rate of 0.1 to 10 Gbit/s; a pump laser system that emits a pump laser light having a second wavelength, different from the first wavelength; a perovskite-doped optical fiber excited by the pump laser light to generate an amplified spontaneous emission spectrum that encompasses the first wavelength so as to receive and amplify the first signal for generating an amplified output signal having the first wavelength; and a photodetector optically coupled to the perovskite-doped optical fiber, and configured to receive the amplified output signal at the high data-rate of 0.1 to 10 Gbit/s. The amplified output signal is encoded with the information.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: February 7, 2023
    Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Boon Siew Ooi, Chun Hong Kang, Tien Khee Ng, Osman M. Bakr
  • Patent number: 11555991
    Abstract: A method for illuminating samples in microscopic imaging methods, wherein a number m of different wavelengths ?i, with m>I and i=I, . . . , m, is selected for the illumination. For each of the wavelengths ?i a target phase function ??i(x, y, ?i) is predefined, wherein x and y denote spatial coordinates in a plane perpendicular to an optical axis z and each target phase function ??i(x, y, ?i) is effective only for the corresponding wavelength ?i. The target phase functions ??i are predefined depending on the structure of the sample and/or the beam shape and/or illumination light structure to be impressed on the light used for illumination. A total phase mask is then produced which realises all target phase functions ??i(x, y, ?i). This total phase mask is then illuminated simultaneously or successively with coherent light of wavelengths ?i such that the predefined structure of the illumination light is generated in the region of the sample.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: January 17, 2023
    Assignee: CARL ZEISS MICROSCOPY GMBH
    Inventors: Joerg Siebenmorgen, Ralf Netz
  • Patent number: 11551877
    Abstract: An object of the present invention is to provide a carbonaceous material used for an electric double layer capacitor having a high electrostatic capacity and capable of maintaining the high electrostatic capacity and energy density over a long period and a method for producing the same. The present invention relates to a carbonaceous material having a specific surface area of 1,200 m2/g to 1,800 m2/g according to a BET method, an R-value of 1.2 or more and a G-band half-value width of 70 cm?1 or more according to a Raman spectrum.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: January 10, 2023
    Assignee: KURARAY CO., LTD.
    Inventors: Shohei Kobayashi, Motomi Matsushima, Seiya Kimachi, Hideharu Iwasaki
  • Patent number: 11536609
    Abstract: The present invention discloses a multi-excitation wavelength spectrometer fluorescence laser radar system, including a multi-wavelength laser emission system, a signal frequency division system and a data storage and display system. The present invention emits lasers with a plurality of wavelengths into the atmosphere simultaneously to alternately excite an organic matter in atmospheric particulate matters and obtain a fluorescence spectrum. The lasers with different wavelengths can excite the same organic matter to obtain different spectra. By analyzing a matrix diagram of each excitation and emission fluorescence spectrum, the present invention effectively explores the features of compositions and concentration of the organic matter in the atmospheric particulate matters.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: December 27, 2022
    Assignee: LANZHOU UNIVERSITY
    Inventors: Zhongwei Huang, Jianping Huang, Wuren Li, Ze Li, Jianrong Bi, Jinsen Shi
  • Patent number: 11520132
    Abstract: A SPIM-microscope (Selective Plane Imaging Microscopy) and a method of operating the same having a y-direction illumination light source and a z-direction detection light camera. An x-scanner generates a sequential light sheet by scanning the illumination light beam in the x-direction. An electronic zoom is provided that is adapted to change the scanning length in the x-direction independently of a focal length of the illumination light beam and a size of the light sheet in the y-direction and in the z-direction, wherein the number of image pixels in x-direction is maintained unchanged by the electronic zoom independently of the scanning length in x-direction that has been selected.
    Type: Grant
    Filed: April 16, 2019
    Date of Patent: December 6, 2022
    Assignee: Leica Microsystems CMS GmbH
    Inventors: Werner Knebel, Wolfgang Oestreicher
  • Patent number: 11512202
    Abstract: The present invention provides a solid color film, a preparation method thereof and a display device. The solid color film includes a transparent substrate and a solid color material dispersed in the transparent substrate, and the solid color material includes a host structure formed of cucurbituril and a guest structure supported on the host structure and formed by bonding a carboxyl group-containing rhodamine-based dye and an aminoadamantane through a chemical bond, wherein the guest structure is bonded to the host structure through the adamantane to form a host-guest structure.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: November 29, 2022
    Inventor: Bao Zha
  • Patent number: 11516387
    Abstract: Pulsed hyperspectral, fluorescence, and laser mapping imaging without input clock or data transmission clock is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a plurality of bidirectional data pads and a controller in communication with the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of: electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, from about 900 nm to about 1000 nm, an excitation wavelength of electromagnetic radiation that causes a reagent to fluoresce, or a laser mapping pattern.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: November 29, 2022
    Inventors: Joshua D. Talbert, Donald M. Wichern
  • Patent number: 11493423
    Abstract: A mold sensor is configured with an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes a sensing system that is configured to measure properties of pressure waves within the enclosed chamber. A controller operates the sensing system and is programmed to detect a presence of mold growing in the chamber based on the characteristics of the pressure wave response within the chamber.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: November 8, 2022
    Assignee: Robert Bosch GmbH
    Inventors: Seow Yuen Yee, Franz Laermer, Thomas Rocznik
  • Patent number: 11428633
    Abstract: The present disclosure relates to systems and methods for cellular imaging and identification through the use of a light sheet flow cytometer. In one implementation, a light sheet flow cytometer may include a light source configured to emit light having one or more wavelengths, at least one optical element configured to form a light sheet from the emitted light, a microfluidic channel configured to hold a sample, and an imaging device. The imaging device may be adapted to forming 3-D images of the sample such that identification tags attached to the sample are visible.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: August 30, 2022
    Assignee: Verily Life Sciences LLC
    Inventors: Cheng-Hsun Wu, Brian M. Rabkin, Supriyo Sinha, John D. Perreault, Chinmay Belthangady, James Higbie, Seung Ah Lee
  • Patent number: 11423306
    Abstract: In one embodiment, a method of determining tag signals from measured intensities, the measured intensities collected by light sensors in a sensor array directed to a sample surface, the sample surface including pixel areas and holding a plurality of clusters during a sequence of sampling events, each light sensor directed to and measuring intensity from one of the pixel areas during each sampling period includes adjustments for background intensity and crosstalk and taking into account signal decay and phasing/pre-phasing. Coefficients for the adjustments can be determined by gradient descent, using as ground truth base calling by the system being characterized or by using reliable base calling of well-characterized sample run through the system being characterized.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: August 23, 2022
    Assignee: Illumina, Inc.
    Inventor: Emrah Kostem
  • Patent number: 11422347
    Abstract: An optical assembly for scanning excitation radiation and/or manipulation radiation in a laser scanning microscope. The assembly an optical scanning unit as a first focusing device for providing a first pupil plane, a first beam deflecting device, which is made of a first scanner arranged in the first pupil plane, for scanning the excitation radiation and/or manipulation radiation in a first coordinate direction, and a second focusing device for generating a second pupil plane, which is optically conjugated to the first pupil plane. A second beam deflecting device is provided for deflecting the excitation radiation and/or manipulation radiation, said second deflecting device being arranged in the second pupil plane. A third focusing device is provided in order to generate a third pupil plane, optically conjugated to the first pupil plane.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: August 23, 2022
    Assignee: Carl Zeiss Microscopy GmbH
    Inventors: Tiemo Anhut, Matthias Wald, Daniel Schwedt, Beate Böhme
  • Patent number: 11386544
    Abstract: An electronics system may include a substrate, an electronic device bonded to the substrate, a plurality of photoluminescent particles disposed on the electronic device, an illuminator, a sensor, and a control module. The illuminator can illuminate the electronic device. The sensor can capture a first set of positions of the photoluminescent particles on the electronic device when the electronic device is not operating under a load and a second set of positions of the photoluminescent particles when the electronic device is operating under a load. The control module can determine thermomechanical stress on the electronic device based at least in part on a difference between the first set of positions and the second set of positions.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: July 12, 2022
    Assignee: TOYOTA MOTOR ENGINEEEING & MANUFACTURING NORTH AMERICA, INC.
    Inventors: Shailesh N. Joshi, Umesh Gandhi, Vishnu Sundaresan, Vijay Venkatesh, Srivatsava Krishnan
  • Patent number: 11385451
    Abstract: A sample imaging device includes a side illumination unit, a two window sample chamber, and refractive index matching. An optically transparent sample holder is in the sample well as is sample immersion fluid. The refractive index matching includes matching of the refractive index of material of a sample to be imaged.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: July 12, 2022
    Assignee: The Regents of the University of California
    Inventors: Per Niklas Hedde, Leonel Malacrida
  • Patent number: 11380095
    Abstract: A work supporting apparatus includes: a visible light camera (visible light image photographing unit) configured to photograph a visible light image; a far-infrared camera (thermal image photographing unit) configured to photograph a thermal image; a work progress status determining unit configured to determine a work progress status from the visible light image photographed by the visible light camera and the thermal image photographed by the far-infrared camera; and a display configured to display a determination result of the work progress status.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: July 5, 2022
    Assignee: MAXELL, LTD.
    Inventors: Daisuke Yoshida, Hiroaki Ito
  • Patent number: 11363939
    Abstract: An endoscope system includes a light source configured to generate either one of first illumination light and second illumination light, an image pickup apparatus configured to obtain an image by picking up an image of an object, and a processor. The processor is configured to make an instruction to set an observation mode of the endoscope system at either one of a first observation mode and a second observation mode, detect an observation state at a time of observing the object based on a feature value calculated from pixel values included in pixels forming a first image, and invalidate an instruction to set the observation mode of the endoscope system at the second observation mode when the observation state at the time of observing the object is not an appropriate observation state.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: June 21, 2022
    Assignee: OLYMPUS CORPORATION
    Inventors: Daiki Ariyoshi, Risa Arai
  • Patent number: 11366060
    Abstract: An apparatus for detecting fluorescent light emitted from a sample comprises: a light source, which is configured to emit excitation light of an excitation wavelength towards a sample comprising fluorophores such that fluorescent light is induced; a photo-detector for detecting light incident on the photo-detector; and an interference filter arranged on the photo-detector, wherein the interference filter is configured to selectively collect and transmit light towards the photo-detector based on an angle of incidence of the light towards the interference filter, wherein the interference filter is configured to selectively transmit supercritical angle fluorescence from the sample towards the photo-detector and suppress undercritical angle fluorescence from the sample.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: June 21, 2022
    Assignees: IMEC VZW, KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Finub James Shirley, Pol Van Dorpe
  • Patent number: 11361429
    Abstract: An MRI method is disclosed for the geometrical characterisation of pulmonary airways on the basis of a first tridimensional image of at least one bronchus of a bronchial tree and includes: acquiring a first MRI image, an MRI sequence being synchronised with a respiratory frequency; filtering the first image; segmenting a portion of the filtered image including the contours of the bronchial tree and its inner volumetric portion; estimating at least one plane of cut of a bronchus; generating at least one image slice of a bronchus; estimating, for each image slice, an area contained within the bronchial wall and/or a bronchial wall thickness.
    Type: Grant
    Filed: May 29, 2017
    Date of Patent: June 14, 2022
    Assignees: UNIVERSITE DE BORDEAUX, L'INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE DE LA RECHERCHE MEDICALE
    Inventors: Gael Dournes, Fabien Baldacci, François Laurent, Patrick Berger
  • Patent number: 11360033
    Abstract: An inspection device includes: an illumination device that irradiates an object with near infrared light; a spectroscope that disperses reflected light from the object irradiated with the near infrared light; an imaging device that takes a spectroscopic image of the reflected light dispersed by the spectroscope; and a processor. The processor: obtains spectral data at a plurality of points on the object based on the spectroscopic image obtained by the imaging device; selects, as typical spectral data representing the object from among the spectral data at the plurality of points, one of: spectral data in which a luminance value in a predetermined wavelength is a median value; and spectral data in which a summation of luminance values in a predetermined wavelength range is a median value; and performs a predetermined analysis for the object based on the typical spectral data and detects a different type of object.
    Type: Grant
    Filed: February 23, 2021
    Date of Patent: June 14, 2022
    Assignee: CKD CORPORATION
    Inventor: Yukihiro Taguchi
  • Patent number: 11340391
    Abstract: An optical filter may include a first group of layers. The first group of layers may include alternating layers of a first dielectric material, of a group of dielectric materials, and a second dielectric material of the group of dielectric materials. The optical filter may include a second group of layers. The second group of layers may include alternating layers of a third dielectric material, of the group of dielectric materials, and a fourth dielectric material of the group of dielectric materials. The optical filter may include a third group of layers. The third group of layers may include alternating layers of a fifth dielectric material, of the group of dielectric materials, a sixth dielectric material, of the group of dielectric materials, and a metal material. The third group of layers may be disposed between the first group of layers and the second group of layers.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: May 24, 2022
    Assignee: VIAVI Solutions Inc.
    Inventor: Georg J. Ockenfuss
  • Patent number: 11333596
    Abstract: An observation container (10) includes: a bottom portion that includes a bottom wall (12A) (first plate part) and a bottom wall (12B) (second plate part) which intersect each other and that is configured to accommodate a liquid sample O as a sample containing microparticles to be imaged by imaging units (30A) and (30B) serving as an imaging device; and a region that has transparency with respect to a wavelength of light used for observation of the microparticles.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: May 17, 2022
    Assignee: Sumitomo Electric Industries, Ltd.
    Inventors: Akinori Kimura, Asako Motomura, Yoko Sugiyama, Hiroshi Suganuma
  • Patent number: 11322906
    Abstract: Apparatus and methods for producing ultrashort optical pulses are described. A high-power, solid-state, passively mode-locked laser can be manufactured in a compact module that can be incorporated into a portable instrument. The mode-locked laser can produce sub-50-ps optical pulses at a repetition rates between 200 MHz and 50 MHz, rates suitable for massively parallel data-acquisition. The optical pulses can be used to generate a reference clock signal for synchronizing data-acquisition and signal-processing electronics of the portable instrument.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: May 3, 2022
    Assignee: Quantum-Si Incorporated
    Inventors: Jonathan M. Rothberg, Jason W. Sickler, Lawrence C. West, Faisal R. Ahmad, Paul E. Glenn, Jack Jewell, John Glenn, Jose Camara, Jeremy Christopher Jordan, Todd Rearick, Farshid Ghasemi, Jonathan C. Schultz, Keith G. Fife, Benjamin Cipriany
  • Patent number: 11293876
    Abstract: A measurement method for visualizing the flow of a fluid that includes: a preparation process where a photochromic compound, whose amount of absorption of light changes upon irradiation with transformation-inducing light, is dissolved in the fluid; a transformation-inducing irradiation process where the fluid is irradiated with transformation-inducing light that causes photochromism; and a post-transformation imaging process where an image of the fluid is taken after irradiation by the transformation-inducing light. During the post-transformation imaging process, a first image is generated by taking an image of the fluid by using first light in the first wavelength range in which the amount of absorption of light changes upon irradiation with transformation-inducing light.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: April 5, 2022
    Assignees: TOKAI UNIVERSITY EDUCATION SYSTEM, KANOMAX JAPAN INC.
    Inventors: Akihiko Azetsu, Ikkei Kitajima, Kazaki Kuratsuji, Masayuki Ochiai
  • Patent number: 11295152
    Abstract: A method and system for object recognition via a computer vision application including an object to be recognized, the object having an object specific luminescence spectral pattern, a light source including at least two illuminants for illuminating a scene including the object to be recognized by switching between the two illuminants, a sensor configured to capture radiance data of the scene including the object when the scene is illuminated by the light source, and a data storage unit storing fluorescence spectral patterns together with appropriately assigned respective objects. The method and system further include a data processing unit configured to extract the object specific fluorescence spectral pattern from the radiance data of the scene and to match the extracted object specific fluorescence spectral pattern with the fluorescence spectral patterns stored in the data storage unit, and to identify a best matching fluorescence spectral pattern and its assigned object.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: April 5, 2022
    Assignee: BASF Coatings GmbH
    Inventors: Yunus Emre Kurtoglu, Matthew Ian Childers
  • Patent number: 11287317
    Abstract: An optical measurement device may include a light source; an emission optic configured to direct a first portion of light generated by the light source to a measurement target; a collection optic configured to receive light from the measurement target; an optical conduit configured to direct a second portion of light generated by the light source to a spectral reference; the spectral reference; a sensor; and a filter. A first portion of the filter may be provided between the collection optic and a first portion of the sensor. A second portion of the filter may be provided between the spectral reference and a second portion of the sensor.
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: March 29, 2022
    Assignee: VIAVI Solutions Inc.
    Inventors: William D. Houck, Valton Smith
  • Patent number: 11275030
    Abstract: This disclosure provides methods and devices for the label-free detection of target molecules of interest. The principles of the disclosure are particularly applicable to the detection of biological molecules (e.g., DNA, RNA, and protein) using standard SiO2-based microarray technology.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: March 15, 2022
    Assignee: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: M. Selim Unlu, David A. Bergstein, Michael F. Ruane, Bennett B. Goldberg
  • Patent number: 11262302
    Abstract: An example system for inspecting a surface includes a laser, an optical system, a gated camera, and a control system. The laser is configured to emit pulses of light, with respective wavelengths of the pulses of light varying over time. The optical system includes at least one optical element, and is configured to direct light emitted by the laser to points along a scan line one point at a time. The gated camera is configured to record a fluorescent response of the surface from light having each wavelength of a plurality of wavelengths at each point along the scan line. The control system is configured to control the gated camera such that an aperture of the gated camera is open during fluorescence of the surface but closed during exposure of the surface to light emitted by the laser.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: March 1, 2022
    Assignee: THE BOEING COMPANY
    Inventors: Keith D. Humfeld, Morteza Safai
  • Patent number: 11255967
    Abstract: A time-to-digital converter includes a self-calibrating, n-stage chain of a number n of gate delay elements connected in parallel and series between a clock signal line for supplying a clock signal and a stop signal line for supplying a stop signal; and a charge-pump and phase-detector unit for the feedback control of the gate delay elements, having a first input as a controlled-variable input, a second input as a reference-variable input, and an output as a correcting-variable output. The clock signal line is connected to the first input of the charge-pump and phase-detector unit, a push-pull line for supplying a push-pull signal is connected to the second input, and, for feedback, the gate delay elements are connected to the output of the charge-pump and phase-detector unit.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: February 22, 2022
    Assignee: Robert Bosch GmbH
    Inventors: Reiner Schnitzer, Rene Adams
  • Patent number: 11249025
    Abstract: Fiducial markers are provided on a patterned array of the type that may be used for molecular analysis, such as sequencing. The fiducial markers may have configurations and layouts that enhance their detection in image or detection data, that facilitate or improve processing, that provide encoding of useful information, and so forth. Examples of the fiducial markers may include non-rectilinear layouts that may provide for more robust location of both the fiducial markers and sites of the patterned array.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: February 15, 2022
    Assignee: Illumina, Inc.
    Inventors: John S. Vieceli, Alex Nemiroski, Paul Belitz, Robert Langlois, M. Shane Bowen, Danny Yuan Chan, Bala Murali K. Venkatesan, Hui Han, Kevan Samiee, Stephen Tanner
  • Patent number: 11249022
    Abstract: A method, apparatus and computer program product are provided to determine the fluorescence lifetime in an efficient manner. In the context of a method electric charge generated by fluorescence emission during two overlapping time periods of a single measurement cycle is stored to form first and second measures. The electric charge generated during that segment of the two time periods during which the two time periods overlap is incorporated in the first measure and in the second measure. The method also includes determining a fluorescence lifetime based at least in part upon the first and second measures.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: February 15, 2022
    Assignee: NOKIA TECHNOLOGIES OY
    Inventors: Marijan Herceg, Tomislav Matic
  • Patent number: 11237108
    Abstract: A biological analysis system can include an excitation module and an emission module. The excitation module can include a collimator element for receiving excitation light from the excitation light source and transmitting collimated excitation light in a first direction, and a plurality of excitation mirrors arrayed along the excitation light path, each excitation mirror disposed at an acute angle relative to the first direction and configured to reflect collimated excitation light along a second direction. The emission module can be positioned to receive excitation light transmitted along the second direction and can include a sample block comprising a plurality of sample receptacles positioned to receive a beam of collimated excitation light, and a plurality of photodetectors configured to receive emission light transmitted from a respective sample receptacle in a direction transverse to the second direction of the excitation light path.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: February 1, 2022
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Ming Song Chen, Chee Woei Chong, Wuh Ken Loh, Wern Yuh Foo, Kuan Moon Boo, Norbert Leclerc, Kristina Uhlendorf, Reiner Koellner, Torsten Fuchs, Stefan Breitfelder