Abstract: The present invention provides a method for preparing 3D brain organoids, comprising the following steps: neurospheres obtained by the RONA method are dissociated into single cells by accutase, plated on a cell culture plate after being counted, cultured in medium A until day 7; neurospheres are cultured in medium B until day 25˜35, and then they are encapsulated by Matrigel; neurospheres are further cultured in media B until day 55˜65, and then they are encapsulated by Matrigel for the second time and cultured continually afterwards. The present invention also provides a medium for culturing 3D brain organoids. The present invention begins with highly purified neurospheres obtained by the RONA method, and neuronal stem cells can be controlled and cultured to achieve true 3D brain organoids with uniform size and structure by this relatively simple method.

Abstract: A method of printing a cellular solid by direct bubble writing comprises introducing an ink formulation comprising a polymerizable monomer and a gas into a nozzle, which includes a core flow channel radially surrounded by an outer flow channel. The ink formulation is directed into the outer flow channel and the gas is directed into the core flow channel. The ink formulation and the gas are ejected out of the nozzle as a stream of bubbles, where each bubble includes a core comprising the gas and a liquid shell overlying the core that comprises the ink formulation. After ejection, the polymerizable monomer is polymerized to form a solid polymeric shell from the liquid shell, and the bubbles are deposited on a substrate moving relative to the nozzle. Thus, a polymeric cellular solid having a predetermined geometry is printed.

Abstract: A system and method for manufacturing three-dimensional structures is provided. The system comprises a plurality of printing stations for performing parallel printing in an confined space enclosed by a housing, wherein each printing station comprises a carrier, a deposition unit with at least one nozzle arranged for dispensing filaments of build material paste through an opening area thereof and a station controller configured to operate the deposition unit for deposition of filaments of a build material paste on the carrier in an interconnected arrangement in a plurality of stacked layers in order to form one or more three-dimensional structures, the at least one nozzle and the detachable carrier being relatively moveable with respect to each other, wherein the deposition unit is coupled to a reservoir unit configured to house the build material paste, wherein the reservoir unit includes at least one reservoir arranged outside of the confined space.

Abstract: The present disclosure describes multi-fluid kits for three-dimensional printing, three-dimensional printing kits, and methods of making three-dimensional printed objects. In one example, a multi-fluid kit for three-dimensional printing can include a fusing agent and an antioxidant agent. The fusing agent can include water and an electromagnetic radiation absorber. The electromagnetic radiation absorber can absorb radiation energy and convert the radiation energy to heat. The antioxidant agent can include water and a dispersion of a secondary antioxidant.

Abstract: A three-dimensional (3D) printing system may comprise a frame; and an additive component(s) configured to couple to the frame. The additive component(s) may comprise a first extrusion unit, a second extrusion unit, and/or a third extrusion unit. The 3D printing system may be a portion of a hybrid computer numerical control (CNC) machining/3D printing system and configured to manufacture a 3D component autonomously from start to finish. The additive component(s) may comprise a heating system including a hot-air blower.

Abstract: The present disclosure relates to an additive manufacturing (AM) method for making a three-dimensional (3D) object, using a part material (M) comprising at least one poly(ether ketone ketone) (PEKK) polymer, in particular to a 3D object obtainable by Fused Deposition Modelling (FDM) or Fused Filament Fabrication (FFF) from this part material (M).

Abstract: A three-dimensional printing support device includes: a variable table which includes an installation surface, and has a configuration configured to enable a shape of the installation surface to be freely modified; a drive unit for: (i) driving the variable table to change the shape of the installation surface; and a control unit for acquiring shape data relating to a shape of a printed article, which is a printing target; and (ii) controlling the drive unit based on the shape data such that the shape of the installation surface corresponds to the shape of the printed article.

Abstract: The production method of the present invention can reuse a non-impregnated catalyzed sol, which has been typically discarded, by recovering the catalyzed sol, which is not impregnated in impregnating of a catalyzed sol into a blanket base, to stop gelating the catalyzed sol, and then using this in subsequently preparing a catalyzed sol.

Abstract: A method (V) for producing a three-dimensional object (2) by applying and selectively solidifying a powdery construction material (13) layer by layer includes the steps: a) applying (Z) a layer of the construction material (13) onto a construction field in a working plane (10) by means of a recoating device (14) moving in a moving direction (B) over the working plane, b) selectively solidifying (Y) the applied layer of the construction material (13) at positions, which correspond to a cross-section of the object (2) to be produced, and c) repeating (X) the steps a) and b) until the object is completed. The construction material is stored during step a) in a recoating unit (40a-e) arranged at the recoating device (14) within a space between two recoating elements (42a, 42b) mutually spaced apart from each other in the moving direction of the recoating device.

Abstract: The disclosure provides a process for manufacturing a tread molding element configured to mold at least a portion of a tire tread, the process comprising the steps of modeling a three-dimensional shape of a tread molding element through a modeling program that can be recognized by a 3D printer; providing one or more plastic compositions comprising one or more thermoplastic polymers having a melting point of at least 180° C.; forming a tread molding element by 3D printing from the one or more plastic compositions; and optionally annealing the tread molding element.

Abstract: The present invention provides a granular material for a fused deposition three-dimensional printer that enables a flexible molded object to be manufactured with high precision. According to the present invention, provided is a granular material for a fused deposition three-dimensional printer. The granular material is formed of a thermoplastic elastomer, and thermoplastic elastomer has a Shore A hardness of 0 to 10 and a melt flow rate of 10 to 200 g/10 min at least one of measurement temperatures of 120 to 230° C.

Abstract: A method of additive manufacturing utilizing selective layer deposition includes measuring a transfuse force between a transfuse roller and a part build surface. An angular position of the transfuse roller is measured over time. A component of a transfuse force variation that is periodic in a rotational period of the transfuse roller is estimated, and a vertical position between the transfuse roller and the part build surface is adjusted to reduce pressure variations in transfuse roller force on the build part surface.

Abstract: The invention discloses a 3D printer based on liquid-solid chemical reaction deposition and operating methods thereof, comprising a sealed forming chamber, a powder container, a forming container, a powder spreading mechanism, and a three-axis linkage mechanism in the sealed forming chamber. The three-axis linkage mechanism moves a nozzle in the sealed forming chamber according to a movement path planning of a control system of the 3D printer. A liquid supply device is provided outside the sealed forming chamber. The liquid supply device contains a gel-like reactant. The nozzle is a liquid nozzle. The liquid nozzle communicates with the liquid supply device through a following conduit.

Abstract: The invention relates to the use of a compatible thermoplastic material (film, sheet, or raft) as the base sheet or layer for 3-D printing an article. The use of the base film provides a means of printing a large article, and of reducing warpage by printing directly on the film. The printed article adheres to the film better than to traditional printer surfaces (glass, metal, glue, or reusable films), because the printed article and film weld together by forming chain entanglements, due to being compatible, miscible, or semi-miscible in the melt.

Abstract: A method of producing a dental object (100), including the steps of producing a pillared support structure (101) on the dental object (100); and producing a lattice structure (103) for reinforcing the support structure (101).

Abstract: Disclosed is a high ultraviolet blocking polylactic acid composite material reinforced by POSS modified bamboo powder. The preparation method therefor includes steps of carrying out chemical grafting modification of bamboo powder with proper particle size by using POSS containing specific organic groups, and then adding the modified bamboo powder to polylactic acid for melting and co-extrusion to obtain POSS modified bamboo powder. The present disclosure makes full use of the 30% lignin in the bamboo powder, having the advantages of wide source, biological metabolizability and low price; the present disclosure does not need the traditional inorganic ultraviolet blocking agent, nor need to extract refined lignin from natural materials, but directly takes inexpensive and easy-to-obtain bamboo powder as main raw material. The composite material prepared in the present disclosure can greatly improve the UV blocking performance, mechanical properties and thermal stability of the PLA.

Abstract: Feedstocks are provided for use in the additive manufacturing of three-dimensional objects via extrusion-based techniques, such as Fused Filament Fabrication (“FFF”) or Fused Deposition Modeling (“FDM”). Generally, the feedstocks may be in the form of substantially continuous filaments and/or in the form of rods of specified length, with diameters in excess of 3.5 mm.

Abstract: In part, the disclosure relates to systems and methods of layer-by-layer assembly of composite structures such as for parts or workpieces. Various additive and subtractive processes can be used. In various embodiments, prepreg tapes that include continuous reinforcing fibers are used. In one aspect, a system that includes printer heads is provided. The printer heads may, in some embodiments, be used for manufacturing high quality continuous fiber reinforced structural parts. In some embodiments, the system includes a first printer head configured to lay down tape (e.g., a thermoplastic tape that includes reinforcing fibers).

Abstract: A liquefier tube for an additive manufacturing system, the liquefier tube including a body provided with a feed channel including a feeding portion having a first diameter, an outlet portion having a second diameter, the first diameter being larger than the second diameter, a transitional portion interconnecting the feeding portion and the outlet portion. The transitional portion has a monotonically decreasing third diameter from the feeding portion to the outlet portion and the third diameter as function of a longitudinal position of the feed channel in the transitional portion between the feeding portion and the outlet portion and at a transition between the transitional portion and the outlet portion is differentiable. Methods of manufacturing the liquefier tube.

Abstract: Methods, particularly automated methods, are provided, as well as 3D-printed composite and hollow objects and 3D-printing systems for printing them. Methods comprise deriving a central line of a hollow 3D object model, calculating reference point(s) and/or line(s) along an inner surface of the hollow 3D object model, and filling the hollow 3D object model with material that comprises a thread defined with respect to the central line and the reference point(s) and/or line(s) and with filling material surrounding the thread. The support construction thus formed may be removed from the 3D object by pulling on the thread, extracting it and the surrounding support filling from the hollow object, thus enabling 3D-printing of convoluted or elongated hollow objects and objects with narrow openings. The parameters of the thread, such as type of curve and thickness, are selected to ensure thread extraction without risk of tearing or knotting the thread.

Abstract: The present invention relates to a three dimensional imaging apparatus (3D printer) having a print head unit with multiple passive micro-sized nozzles, wherein the passive micro-sized nozzles are also integrated with material interfaces. The print head unit comprises a nozzle gripper mechanism for picking said passive micro-sized nozzle, a filament or rod feeding mechanism for feeding the material, and a heating mechanism arranged for contactless heating regulating of the lower portion of said passive micro-sized nozzle. A method for printing a three-dimensional object of multi-materials by using an innovative three dimensional imaging apparatus having a print head with multiple passive nozzles is also disclosed. The three-dimensional imaging apparatus is capable of providing different types of materials as well as different color of the materials for creating three-dimensional object.

Abstract: Provided is a method of producing a manufactured object including forming the manufactured object by performing, once or a plurality of times, a step of forming a powder layer from material powders containing powders of an inorganic compound and a step of irradiating a predetermined region of a surface of the powder layer with an energy beam and thereby fusing/solidifying the material powders. In the step of fusing/solidifying the material powders, an amorphous-rich region and a crystalline-rich region are formed separately by changing at least one of an output of the energy beam, a relative position between the surface of the powder layer and a focus of the energy beam, and a scanning rate.

Abstract: Provided herein are methods for making three-dimensional parts by additive manufacturing using a debondable curable coating composition on the build surface.

Abstract: A method of making a PEEK-PEmEK copolymer having RPEEK and RPEmEK repeat units in a molar ratio RPEEK/RPEmEK ranging from 95/5 to 45/55, the PEEK-PEmEK copolymer obtained from the method and the polymer composition including the PEEK-PEmEK copolymer, at least one reinforcing filler, at least one additive, or a combination thereof, shaped articles including the polymer composition, polymer-metal junctions including the polymer composition. Also described are methods of making the polymer composition, methods of making the shaped articles, and methods of making the polymer-metal junctions.

Abstract: Copolymers for use in a digital manufacturing process, in particular support materials for use in a digital manufacturing process comprising such copolymers. More particularly, the invention is directed to a copolymer, a support material based on the the copolymer, the use of the copolymer in a digital manufacturing process, a method for preparing the copolymer and a method for building a 3D-model by using a support material comprising the copolymer.

Abstract: The disclosure discloses a bionic digestive tract as well as a preparation method and application thereof, belonging to the field of bionic technologies and the field of biological technologies. The bionic digestive tract of the disclosure is prepared by mixing a base material (one or more of silica gel, latex and hydrogel) and auxiliary materials (silicone oil and a curing agent) in a certain mass ratio (the mass ratio of the base material to the silicone oil to the curing agent is 100:(0.5 to 10):(0.5 to 3.5)). The simulation performance of the bionic digestive tract is excellent, has strong consistency with a true human digestive tract in terms of performance, structure and function, can simulate the true states of food, drugs and microorganisms in a digestive system, and has great application prospects in the research process of food and drugs.

Abstract: The present invention relates to a method for three dimensional printing of a porous object enabling the capillary transport of hydrophilic fluids, for use as liquid handling device, for example as a point of care diagnostic device. The invention also provides the porous object obtainable or obtained by such methods, and its use in liquid handling or as a point of care diagnostic device.

Abstract: A method of 3D printing a part with an extrusion-based additive manufacturing system includes providing a filament having a semi-crystalline material as a majority component of a polymeric matrix to a liquefier having a liquefier tube having an overall length between an inlet end and an outlet end. An upper portion of the liquefier tube adjacent the inlet end has a first length and a first cross-sectional area substantially perpendicular to a longitudinal axis and a lower portion of the liquefier tube adjacent the outlet end has a second length and a second cross-sectional area substantially perpendicular to the longitudinal axis, wherein the first cross-sectional area is greater than the second cross-sectional area. The method includes driving the filament into a melt zone located within the upper portion of the liquefier tube at a selected rate based upon a desired extrusion rate. The filament is melted within the melt zone forming a melt pool in the liquefier tube to provide the selected extrusion rate.

Abstract: A system for generating slice data for additive manufacturing, comprises a graphics processing unit (GPU) that receives a digital model of an object in a three-dimensional build space defined over a plurality of slices, computes a three-dimensional signed distance field over voxels in the build space, assigns a building material to each voxel based on a respective distance field value, and generates slice data output pertaining to the building material assignments for each slice. The slice data output can be used for printing the object in layers corresponding to the slices. The distance field comprises one or more vector having a vertical component with respect to the slices.

Abstract: Systems and methods may support build direction-based partitioning for construction of a physical object through additive manufacturing. In some implementations, a system may access a surface mesh representative of a 3D object and an initial build direction for construction of the object using additive manufacturing. The system may partition the surface mesh into an initial buildable segment and a non-buildable segment based on the initial build direction. The system may iteratively determine subsequent build directions and partition off subsequent buildable segments from the unbuildable segment until no portion of the non-buildable segment remains. The determined buildable segments and correlated build directions may be provided to a multi-axis 3D printer for construction of the represented 3D object through additive manufacturing.

Abstract: An example of a three-dimensional (3D) printing kit includes a build material composition and a fusing agent to be applied to at least a portion of the build material composition during 3D printing. The build material composition includes a polyamide having a melt enthalpy ranging from greater than 5 J/g to less than 150 J/g. The fusing agent includes an energy absorber to absorb electromagnetic radiation to coalesce the polyamide in the at least the portion. The fusing agent is a core fusing agent and the energy absorber has absorption at least at wavelengths ranging from 400 nm to 780 nm; or the fusing agent is a primer fusing agent and the energy absorber is a plasmonic resonance absorber having absorption at wavelengths ranging from 800 nm to 4000 nm and having transparency at wavelengths ranging from 400 nm to 780 nm.

Abstract: An example of a method, for three-dimensional (3D) printing, includes applying a build material and patterning at least a portion of the build material. The patterning includes selectively applying a wetting amount of a binder fluid on the at least the portion of the build material and subsequently selectively applying a remaining amount of the binder fluid on the at least the portion of the build material. An area density in grams per meter square meter (gsm) of the wetting amount ranges from about 2 times less to about 30 times less than area density in gsm of the remaining amount.

Abstract: Exemplary embodiments of the present invention control a forming unit of a 3D printer so as to additionally form a second object in a free space in the forming unit when receiving an instruction to form the second object and forming data in the middle of a forming process for a first object by the forming unit.

Abstract: A method and printing system for printing a three-dimensional structure, in particular an optical component, by depositing droplets of printing ink side by side and one above the other in several consecutive depositing steps by means of a print head. In each depositing step a plurality of droplets is ejected simultaneously by a plurality of ejection nozzles of the print head. The print head is moved relative to the deposited droplets in a moving step performed between at least two consecutive depositing steps in such a manner that the droplets deposited in the same position in the at least two consecutive depositing steps are ejected at least partly from two different ejection nozzles.

Abstract: A three-dimensional printing system includes a print bed and a shelf insertion mechanism for inserting a shelf of one or a plurality of auxiliary shelves into a print volume between the print bed and a printer head. A printer assembly is configured to deposit layers of material within the print volume to form one or more objects on a support platform, the support platform including the print bed or an auxiliary shelf that is inserted into the print volume by the shelf insertion mechanism. A controller is configured to control the shelf insertion mechanism to insert an auxiliary shelf between the print bed and a printer head of the system after formation of the objects on that support platform by the printer assembly is complete.

Abstract: Systems and methods for forming an object using additive manufacturing. One method includes receiving a digital model of the object, predicting a shrinking characteristic or receiving a predicted shrinking characteristic of the object that will occur during thermal processing of the object, once formed, and generating, based on the shrinking characteristic of the object, instructions for forming a raft on which the object will be formed. The instructions for forming the raft are configured to form a raft having a shrinking characteristic that reflects the shrinking characteristic of the object.

Abstract: The extraction of a three-dimensional (3D) object is facilitated using a printed hint, which includes an additional shape that is printed along with the 3D object in a granular-based printer bed. In example implementations, the hint is indicative of a location of the 3D object. In one example, a hint has a dimension indicative of a depth to the object in the printer bed. In another example, a position of a hint is indicative that the object is below, and a size of the hint is based on a size of the object. Some hints can also protect the object. Examples include plate and shell-shaped hints. The object is located under a plate hint or within a shell hint. Further, an appearance of the object or indications of the sturdiness of different parts of the object can be printed on the hint to facilitate a safe extraction of the object.

Abstract: Stapling assemblies for use with a surgical stapler are provided. In one exemplary embodiment, the stapling assembly includes a cartridge having a plurality of staples disposed therein and a non-fibrous adjunct formed of at least one fused bioabsorbable polymer and configured to be releasably retained on the cartridge. Adjunct systems for use with a surgical stapler are also provided. Surgical end effectors using the stapling assemblies are also provided. Methods for manufacturing stapling assemblies and using the same are also provided.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for working with three-dimensional object models for printing. One of the methods includes determining a plurality of infill structures in a slice of an object; and determining a path for the tool-head to create the plurality of infill structures including: determining a first portion of the path for deposition of a first infill structure during a first time period; determining a second portion of the path for deposition of one or more second infill structures that are not adjacent to the first infill structure during a second time period; and determining a third portion of the path for deposition of a third infill structure that is adjacent to the first infill structure, wherein the second time period is determined to allow the first infill structure to cool before deposition of the third infill structure.

Abstract: A manufacturing installation for the additive manufacturing of components, each provided with at least one material overhang, has at least one building platform on which the particular component can at least partially be additively manufactured. In order to reduce the material consumption and the time to produce additively manufactured components, the manufacturing installation has at least one preferably electrically controllable support device with at least one movable support arm for the at least temporary holding of at least one support element, arranged on the support arm, during the additive manufacture of the particular component above the building platform.

Abstract: A system determines an object part density relative to a build region in a layer of build material used in an additive manufacturing machine, the object part density based on a relative portion of the build region where an energy absorbing agent is applied. The system controls a thermal characteristic of the build region in the layer of build material based on the determined object part density.

Abstract: A method for 3D printing of a robot element, more particularly a finger for use in robotics. At least one sensor is concomitantly printed by means of multi-material printing during the printing of the robot element. A gripping element produced by a method of this kind includes a number of printed layers of robot element material and a concomitantly printed sensor.

Abstract: A manufacturing method for a shaped object for manufacturing the shaped object used as a parts when creating a three-dimensional object assembled by combining multiple parts, where the shaped object including a surface region, an end region, and an inner region is shaped. A surface colored portion, which is a portion to be colored in the surface region, is formed, so that a light entering from a side opposite to the inner region is reflected by the inner region to an outside of the shaped object. And, an end colored portion, which is a portion to be colored in the end region, is formed to have a light reflectivity higher than that of the surface colored portion using a coloring material and a light reflective material.

Abstract: An additive manufacturing apparatus includes: first and second spaced apart side walls extending along a pre-defined path and defining a build chamber therebetween; one or more build units mounted for movement along the pre-defined path, the one or more build units including at least one of: a powder dispenser positioned above the build chamber; an applicator configured to scrape powder dispensed into the build chamber; and a directed energy source configured to fuse the scraped powder.

Abstract: The present invention is a composition of an agent for treating a precursor of a three-dimensional object for removing a support material from the precursor of the three-dimensional object containing a three-dimensional object and the support material containing a (meth)acrylic acid-based copolymer having a hydrophilic monomer and a hydrophobic monomer as a monomer unit; the composition of the agent for treating the precursor of the three-dimensional object having at least one or more type of organic amine compounds selected from the group consisting of a secondary monoamine compound, a tertiary monoamine compound, a secondary diamine compound, and a tertiary diamine compound; in which a total content of alkali metal hydroxide and alkali metal carbonate is less than a content of the organic amine compound and less than 2.5% by mass.

Abstract: The invention shows a material provision device for a stereolithography apparatus to provide print material (16), in particular a photopolymer, to be cured, wherein the material provision device (10) surrounds an in particular limp material cartridge (12) which receives the print material (16) on all sides and (UV) light-proof, and the material cartridge (12) comprises an outlet (20) via which the print material (16) may be dispensed and which is received in a connection (43) or a spout in the material provision device (10) and is at least partially supported thereon or therein or seals against it.

Abstract: Methods for additive manufacturing using a three-dimensional printer including at least one linear feed mechanism and a print head positioned proximate a build platen are disclosed. The methods include a step of providing and/or feeding an unmelted fiber reinforced composite filament at a feed rate by the at least one linear feed mechanism. The methods include heating the filament to a temperature at which a matrix material therein flows within at least one rounded outlet of the print head. The methods include moving the print head and the build platen relative to one another at a printing rate. The methods include applying a spreading force to the filament between the at least one rounded outlet of the print head and the build platen. The methods include a step of controlling a differential in the feed rate and printing rate using the at least one linear feed mechanism so that the feed rate and the printing rate are substantially the same.

Abstract: According to one aspect there is provided a three-dimensional printer. The printer comprises a controller to obtain data relating to a layer of a build model, to process non-empty layers according to a first operating mode and to process empty layers according to a second operating mode.

Abstract: A thermoplastic elastomer composition having: at least one elastomer component selected from the group made of elastomeric polymers (A) each of which has a side chain containing a hydrogen-bond cross-linkable moiety having a carbonyl-containing group and/or a nitrogen-containing heterocycle and has a glass-transition point of 25° C. or below, and elastomeric polymers (B) each of which contains a hydrogen-bond cross-linkable moiety and a covalent-bond cross-linking moiety in a side chain and has a glass-transition point of 25° C. or below; an organically modified clay, a content ratio of which is 20 parts by mass or less relative to 100 parts by mass of the elastomer component; and a polymer (Z) which is a polymer other than the elastomeric polymers (A) and (B), and an SP value of which is 9.0 or more and is greater by 0.5 or more than an SP value of the elastomer component.

Abstract: A method of manufacturing an object comprises applying a layer of building material in powder form having a predetermined thickness onto a layer of the building material already previously applied which has been solidified in a region corresponding to a cross section of the object. A recoater is moved in a direction across the layer already previously applied, and the building material is solidified in a shape corresponding to a cross section of the object. Prior to the application of a layer, for a solidified region having a thickness in the layer applied before, the maximum of the product of the extension of this region in movement direction of the recoater and the thickness is determined and during the application of the layer, at least an additional powder amount proportional to the value of the maximum is additionally provided.