Abstract: A method for determining reading distance for an individual made to observe a reading zone includes positioning the individual in front of an apparatus to learn their reading distance. The individual reads of a zone that is placed on a portable tablet and equipped with at least one location marker. At least one image is acquired allowing at least one facial reference point of the individual and each marker of the reading tablet. The images is processed taking into account the position of the facial reference point of the individual and the position of the at least one marker of the tablet and the indicating of the reading distance is conveyed.

Abstract: A system and associated methods for animated image vision testing is disclosed. In at least one embodiment, a vision test includes at least one animated dynamic optotype image for measuring the visual acuity of a subject. The animated image vision test takes advantage of the ability of the human eyes to detect both distance and motion. Moving images, such as rotating segmented circles, let the eyes detect motion as to the size, distance, and rotation direction of that moving image. That motion detection is much more precise than the interpretation of multiple static letters or static images. Using rotating images for vision testing rather than static images creates an acuity test more accurate than current tests, a test that is faster to use, and a test that does not require the ability to read.

Abstract: A light source generates light to fixate a gaze of an eye to be examined, while a scanning unit performs main-scanning and sub-scanning on a fundus of the eye to be examined with the light from the light source.

Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.

Abstract: A visual therapy system is provided that includes a computer, a projector, a display, and input devices, including a head sensor remote, a sensor bar, a balance board, hand controlled remote, and a head sensor. The system uses an interactive interface and blue tooth software that combines remotes, an interactive balance board and infra-red head sensors. The system provides specialized therapy modules which may be based on the concept of Top Down Processing and may be designed to enhance ocular motor control, visuomotor and binocular performance while integrating vision, auditory, proprioception, balance and visuomotor control.

Abstract: A noninvasive method and apparatus for determining analyte concentration (e.g., glucose) in a subject that includes measuring light refraction from at least a portion one or more structures. One example of such structure is the subject's iris.

Abstract: An ophthalmological measuring system for determining distances and/or for tomographic imaging of ocular structures, based on an OCT method. The measuring system includes a light source with a spectral centroid (?), an interferometric measuring device, a scanner system, which in addition to the lateral deflection of the sample beam also has axial modulations with a frequency (f) in the sample arm, and a control and evaluation unit. The scanner performs a lateral, two-dimensional deflection of the sample beam with the aid of one or even two separate mirror elements and can in particular have axial modulation amplitudes zM>>?/2. The system can also be used for scanner systems in other fields that use an OCT method, in particular a swept-source OCT method.

Abstract: Systems and methods are provided for monitoring eye movements of a user, and diagnosing and treating eye conditions substantially in real-time. A visual display device is provided with optical display fields corresponding to eyes of the user, and a controller linked to the device is programmed to measure eye positions with respect to the display device and determine optical deviations in any eye with respect to a central visual axis of the other (dominant) eye. In response to deviations exceeding a first value, an occlusion spot is generated in the display field for the dominant eye of a size corresponding to the degree of optical deviation. The location of the occlusion is continuously adjusted in accordance with real-time movements of the dominant eye based on the received signals from the device. When the optical deviation falls below a second value, occlusion of the dominant eye is disabled.

Abstract: A visual function evaluation is performed using a sequence of interactions with a mobile device. A patient user may perform a variety of visual tests using the mobile device. The mobile device transmits the test results to a remote server implementing analysis of the visual function results using network service. The network service receives the test results, processes the results, and provides the processed results to a healthcare provider. The processed results may include trends of the user's visual function test performance. The healthcare provider, such as a physician, may optimize and administer treatment based on the data. Early detection of changes in visual function can enable the healthcare provider to individualize treatment, helping to prevent vision loss while minimizing visits to the office, discomfort, and expense.

Abstract: An image processing apparatus includes: an acquisition unit configured to acquire a tomogram of an eye portion of a patient to be examined; an information acquisition unit configured to acquire information of a predetermined portion and position information of a predetermined tissue structure from the tomogram; and a calculation unit configured to calculate an evaluation value based on a relationship between the information of the predetermined portion and a position of the predetermined tissue structure.

Abstract: A new tomographic image is generated using a reverse image in which at least one portion of a tomographic image of a retina of an eye to be examined is reversed and the tomographic image so that the reverse image is located on a side on which the retinal layer in the tomographic image is in contact with an end of the tomographic image.

Abstract: Improved systems and methods for ocular tomography are provided. These systems and methods can be used to improve the effectiveness of a wide variety of different ophthalmic diagnostic procedures, and various surgical and non-surgical treatments. One embodiment provides a system and method for determining ocular tomography data for the eye using a plenoptic detector. For example, an ocular tomography system can comprise a set of light sources configured to illuminate an eye, a plenoptic detector configured to receive images of the light sources reflected from surfaces of the eye and generate plenoptic image data representing the images, and a processing system coupled to the plenoptic detector. The processing system is configured to analyze the plenoptic image data to determine tomography data for the eye.

Abstract: A method for detecting amyloid beta plaques and drusen is disclosed. The method for detecting amyloid beta plaques and drusen may include applying a combination of optical retro mode illumination techniques to acquire a plurality of amyloid beta plaques and drusen images that are too small to be seen with other imaging modalities. The amyloid beta plaques and drusen images may also be detected with a non-transitory computer storage media having instructions stored thereon which, when executed, execute the method for detecting amyloid beta plaques and drusen. The method may track changes in plaque, size, area and density of the amyloid beta plaques and drusen over a predetermined period of time.

Abstract: The invention is directed to quantification of the effects of drugs on a patient using pupillometric measures. Apparatus and processes for obtaining control and patient measures and deriving relationships from same are provided.

Abstract: Disclosed are various embodiments for automatic scrolling of content displayed on a display device in response to gaze detection. Content may be displayed in a window rendered on a display screen. Gaze detection components may be used to detect that a user is gazing at the displayed content and to determine a gaze point relative to the display screen. At least one applicable scroll zone relative to the display screen and a scroll action associated with each applicable scroll zone may be determined. In response to determining that the gaze point is within a first applicable scroll zone, an associated first scroll action may be initiated. The first scroll action causes the content to scroll within the window until at least one of: expiration of a defined period, determining that a portion of the content scrolls past a defined position within the window, determining that the gaze point is outside of the first scroll zone, and detecting an indicator that the user begins reading the content.

Abstract: The present disclosure relates generally to a system and method for determining the refractive error of a patient, more particularly determining the patient's refractive error by using a computerized screen, and providing the patient with a prescription for the patient's preferred type of corrective lenses. The system and method do not require the trip or expense of a doctor visit, and are optimized for convenience and cost effectiveness. In a general embodiment, the present disclosure provides a method for determining a corrective lenses prescription of a patient. The method includes, separately, for each eye of the patient, determining the astigmatism prescription of the patient via a computerized screen, and determining the power of the corrective lenses prescription of the patient via the computerized screen.

Abstract: An optical device combination with a portable electronic device utilizes a user's autonomic response to truth/false or beneficial/non-beneficial stimulus and provides immediate feedback to the user in the context of an applied kinesiology exam. Through measurements of the pupils dilation or constriction and processing of the measurements by the portable electronic device, the response is obtained and feedback is provided that reflects the pupillary response. The device and method effectively eliminate the subjective components of prior art muscle testing response from the hands of the testing user as well as providing a simple convenient and portable attachment to a user's smart phone.

Abstract: An imaging probe for imaging a sample includes at least one light source that provides light to a sample. The imaging probe also includes a first imaging objective that focuses a first light reflected from the sample and a second light reflected from the sample, such that the first light and the second light share at least a portion of an imaging path. The imaging probe also includes a first optical component that receives the first light and the second light from the first imaging objective, directs the first light towards an imaging camera to obtain a first image of the sample, and directs the second light toward an optical coherence tomography (OCT) imaging apparatus to obtain a second image of the sample.

Abstract: A quantitative method to analyze phase-resolved, raw backscatter echo data or the envelope of phase-resolved, raw backscatter echo data to characterize vitreous inhomogeneities as they relate to normal aging and vitreo-retinal disease. The technique can be applied to 2D or 3D data acquired from the vitreous. The approach provides an objective end value to characterize the vitreous and provide a tool for early diagnosis, monitoring and planning treatment of vitreo-retinal diseases.

Abstract: Systems and methods for locating the center of a lens in the eye are provided. These systems and methods can be used to improve the effectiveness of a wide variety of different ophthalmic procedures. In one embodiment, a system and method is provided for determining the center of eye lens by illuminating the eye with a set of light sources, and measuring the resulting first image of the light sources reflected from an anterior surface of the lens and the resulting second image of the light sources reflected from a posterior surface of the lens. The location of the center of the lens of the eye is then determined using the measurements. In one embodiment, the center of the lens is determined by interpolating between the measures of the images. Such a determination provides an accurate location of the geometric center of the lens.

Abstract: Embodiments of this invention generally relate to systems and methods for wavefront interactive refraction display and more particularly to systems and methods for capturing and displaying eye wavefront interactive refraction data based on the desired refractive state of the patient's eye.

Abstract: Embodiments described herein provide improved systems and methods for corneal pachymetry. These systems and methods can be used to improve the accuracy of corneal measurements that are used for a wide variety of different ophthalmic procedures. One embodiment provides a system and method for corneal pachymetry using a plenoptic detector. For example, a corneal pachymetry system can comprise a light source, a plenoptic detector and a processing system coupled to the plenoptic detector. The light source is configured to illuminate the cornea of the eye, and the plenoptic detector is positioned at an angle relative to the eye. The plenoptic detector is configured to receive an image of the light source reflected from the cornea and generate plenoptic image data representing the images. The processing system is coupled to the plenoptic detector and is configured to analyze the plenoptic image data to accurately determine the corneal thickness of the eye.

Abstract: A method for detecting strabismus in at least one image comprising a subject's eyes, wherein the at least one image has been obtained using an apparatus comprising a light source and a target offset from the light source, the method comprising, for each of the subject's left and right eyes: determining, from the image, a reflection offset distance, being the distance between a reference point of the eye and a reflection of a light source on the eye; determining a difference between the reflection offset distance and a reference reflection offset distance for the corresponding left or right eye, wherein the reference reflection offset distance has been determined based on relative positions of the light source, the target and the subject's head; and determining whether the difference is less than a difference threshold value for determining whether the subject has a strabismus.

Abstract: Systems and methods for improved acquisition of ophthalmic optical coherence tomography data are presented, allowing for enhanced ease of use and higher quality data and analysis functionality. Embodiments include automated triggering for detecting and initiating collection of OCT ophthalmic data, an automated technique for determining the optimal number of B-scans to be collected to create the highest quality image and optimize speckle reduction, automated review of fundus images collected with an adjunct imaging modality to guide the OCT data collection, a single scan protocol in which a large field of view is collected with HD B-scans embedded at different locations depending on automated analysis of either a fundus image or sparse OCT scan, and various scan configurations for imaging eyes with large axial depth range.

Abstract: Improved systems and methods for ocular topography and using a plenoptic detector are provided. For example, a multifunction ocular topography and aberrometry system can comprise a first set of light sources, a second light source, a plenoptic detector and a processing system coupled to the plenoptic detector. The first set of light sources and the second light source are configured to selectively illuminate an eye. The plenoptic detector is configured to selectively receive images of the first set of light sources reflected from a corneal surface of the eye and generate first plenoptic image data representing the images of the first set of light sources. The plenoptic detector is further configured receive images of the second light source reflected from a retina of the eye and generate second plenoptic image data representing the images of the second light source.

Abstract: Systems and methods for variable depth optical coherence tomography (OCT) imaging with a swept laser source are presented. Swept-source OCT data acquired at two different spectral resolutions is resampled using information on the wavenumber nonlinearity of the source to generate OCT images at two different depths.

Abstract: A method for determining ocular and optical measurements for the production and fitting of corrective eyeglasses for a user with the aid of the a camera. The method utilizes a protocol for reconstructing the system of the user's eyes in three dimensions by modeling the system of the eye, thereby providing precise ocular and optical measurements. The method uses test objects that are connected or not connected to the user's face.

Abstract: An intraocular lens (IOL), system, and method having a base lens and a complementary lens selected to form a curved image surface matching a retina surface when placed in an eye's line of sight.

Abstract: Systems and methods for modifying an eye including a light source with light elements, a photodetector producing a signal representing images of the light elements and corresponding to locations on an ocular surface, an optical system directing light from the light elements reflected by the ocular surface onto the photodetector, a memory including code for processing the signal, and a processor for executing the code and outputting shape data for use in calculating a treatment plan for the eye. The code includes instructions for determining the shape data based on a combination of zonal reconstruction and polynomial fitting using the plurality of images.

Abstract: An eyesight testing apparatus examines associated heterophoria of the eyes of a subject. The apparatus includes an image generation device having a display unit for generating test patterns for display to the eyes. An optical assembly is arranged on that side of the display unit facing the eyes. This assembly separates light supplied by a first group of selected zones of the display unit from light supplied to a beam path by a second group of selected zones of the display unit. The left eye only receives the light from the first group. The light from the second group only passes to the right eye. The optical assembly includes a prism matrix having a multiplicity of prism portions extending in the vertical direction and each having a lens-shaped region with a convex surface facing the display unit.

Abstract: An apparatus for imaging an eye includes a housing and a system of optical components disposed in the housing. The apparatus is capable of operating in a line scanning laser ophthalmoscope (LSLO) mode and an optical coherence tomography (OCT) mode. The system of optical components can include a first source to provide a first beam of light for the OCT mode and a second source to provide a second beam of light for the LSLO mode. In the OCT mode, a first optic is used that (i) scans, using a first surface of the first optic, the first beam of light along a retina of an eye in a first dimension, and (ii) descans, using the first surface, a first light returning from the eye in the first dimension to a detection system in the OCT mode. In the LSLO mode, the first optic is used where the second beam of light passes through a second surface of the first optic.

Abstract: An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina.

Abstract: Provided is an imaging apparatus using Fourier-domain optical coherence tomography, the imaging apparatus removing noises caused by the autocorrelation component of returning light to obtain a high-resolution tomographic image. A first switching unit 17 switches a first state in which returning light 12 is combined with reference light (a state in which the returning light 12 is conducted to a combining unit 22) and a second state different from the first state (a state in which the light path of the returning light 12 is blocked or changed). A controlling unit 18 controls the switching unit 17 to change the first and the second state. A interferometric information acquiring unit 19 acquires interferometric information on the returning light 12 and the reference light 14 using the reference light 14 or the returning light 12 detected by the detecting unit 16 in the second state and the combined light 15.

Abstract: The disclosure relates to medical databases, remote monitoring, diagnosis and treatment systems and methods. In one particular embodiment, a system for remote monitoring, diagnosis, or treatment of eye conditions, disorders and diseases is provided. This method generally includes administering a stream of droplets to the eye of a subject from an ejector device, and storing data related to the administration in a memory of the ejector device. The data may then be monitored and analyzed.

Abstract: An imaging apparatus according to the present invention can cause a display unit to display a scanning range of each of a plurality of measurement light beams in an intersection image (an image in a direction intersecting a direction in which an inspection object is irradiated with the plurality of measurement light beams) of the inspection object.

Abstract: In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's/subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector.

Abstract: Systems, methods, and apparatuses for amblyopia and ocular deviation correction, as well as visual interfaces, are disclosed. In one aspect, embodiments of the present disclosure include a system for amblyopia correction, the system includes, an image processing unit to identify a set of image parameters and, when, in operation, the image processing unit modifies a source visual content based on one or more of the set of image parameters to generate visual content and a visualization unit coupled to the image processing unit operable to receive visual content from the image processing unit, the visualization unit having a screen, when, in operation, the screen displays the visual content.

Abstract: One embodiment is an apparatus/system for providing feedback to a procedure. The apparatus includes a real time wavefront sensor for measuring the wavefront of an optical beam, a real time video camera for capturing a scene where the optical beam comes from, a computer for processing the captured wavefront data and synchronizing the data with the video and outputting the synchronized information to a display, and a display for simultaneously displaying the synchronized wavefront and video information. Another embodiment of the present invention is a method for providing feedback to a procedure. The method involves the steps of measuring the wavefront of an optical beam with a real time wavefront sensor; capturing a video of a scene from which the optical beam comes; processing the captured wavefront data and synchronizing it with the video; and simultaneously displaying the wavefront information with the video on the same display screen.

Abstract: An ophthalmological analysis instrument for measuring a topography of a surface of an eye includes a projection apparatus and a monitoring apparatus. The projection apparatus has at least one illumination device and an aperture device. The illumination device has a first light source, which can emit light in a predominantly monochromatic spectrum, it being possible to image an image pattern on a surface of an eye by the aperture device. Images of the imaged image pattern being recordable by the monitoring apparatus, and a topography of the surface of the being derivable from the images, wherein the illumination device has at least one further light source, which can emit polychromatic light in a predominantly visible spectrum.

Abstract: Embodiments of automatically aligning imager are presented. In accordance with some embodiments, an imaging system includes an adjustment stage; an auto-alignment optics mounted on the adjustment stage and coupled to image an object, the auto-alignment optics including at least one video camera providing an image of the object; imaging scanning optics mounted on the adjustment stage and coupled to scan the object; an imager coupled to the imaging scanning optics; and a processor coupled to the adjustment stage and the auto-alignment optics, the processor executing instructions to receive the image of the object and adjust the adjustment stage to align the optics with the imaging scanning optics.

Abstract: An image processing apparatus obtains a plurality of moving images of a predetermined site of an eye, specifies a vascular region by using at least one moving image of the plurality of moving images, and measures the sizes of blood cell aggregates in a specific vascular branch in the specified vascular region for each moving image of the plurality of moving images.

Abstract: Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on tear film characteristics analysis and dry eye symptoms are disclosed. In embodiments herein, imaging of the ocular tear film is performed during contact lens wear. An analysis of the image of the ocular tear film is performed to determine one or more tear film characteristics of the ocular tear film. The tear film characteristics can be used to determine the effect or possible effect of contact lens wear on the ocular tear film, and thus be used to determine contact lens intolerance of the patient. The tear film characteristics used to analyze contact lens intolerance based on images of the ocular tear film involving contact lens wear may include dry eye symptoms, including but not limited to tear film (e.g., lipid and/or aqueous) thickness, tear film viscosity, and tear film movement rate in the eye.

Abstract: An ocular fundus information acquisition device includes: a fixation target provision section configured to provide a continuously moving fixation target; an ocular fundus image acquisition section configured to acquire an image of an ocular fundus in a subject's eye while the subject is closely watching the continuously moving fixation target; and an ocular fundus information acquisition section configured to acquire ocular fundus information from the acquired ocular fundus image.

Abstract: An image data set acquired by an optical coherence tomography (OCT) system is corrected for effects due to motion of the sample. A first set of A-scans is acquired within a time short enough to avoid any significant motion of the sample. A second more extensive set of A-scans is acquired over an overlapping region on the sample. Significant sample motion may occur during acquisition of the second set. A-scans from the first set are matched with A-scans from the second set, based on similarity between the longitudinal optical scattering profiles they contain. Such matched pairs of A-scans are likely to correspond to the same region in the sample. Comparison of the OCT scanner coordinates that produced each A-scan in a matching pair, in conjunction with any shift in the longitudinal scattering profiles between the pair of A-scans, reveals the displacement of the sample between acquisition of the first and second A-scans in the pair.

Abstract: The invention relates to a method for measuring at least one geo-morphometric parameter of an individual wearing glasses (10), said method involving a stand-alone computing device (1) comprising: a screen (8); a target (12); a compact image acquisition system (7) comprising a means for determining its inclination and connected to said screen (8); and a processing unit allowing the image acquisition system (7) to be controlled and the images obtained to be processed.

Abstract: Methods for improving gaze tracking are presented. These methods eliminate the need for a separate initial calibration step to determine whether the subject is properly centrally fixated during testing. In one embodiment, whether the subject is centrally fixated is determined by identifying inlier and outlier gaze descriptors; the inliers are assumed to be associated with central fixation. This reduces the total time required for testing. These methods also improve the accuracy of gaze tracking during testing without the need for individual subject calibration. Instead, a database of reference eyes is used. The subject's eye can be compared to the reference eyes, and the mapping function for one or more reference matches can be used to estimate the subject's gaze direction. In another embodiment, previous calibration data from the same subject can be used to determine whether the subject is properly centrally fixated and/or the direction of the subject's gaze.

Abstract: Provided is a light intensity control apparatus including: a photometry value calculation portion for measuring reflected light from a fundus under illumination of an observation light source; an observation light source control portion for controlling a light intensity of the observation light source based on photometry information obtained by the photometry value calculation portion, the light intensity of the observation light source obtained in the measurement, and a correction value of the light intensity of the observation light source; and a photographing light source control portion for controlling a light intensity of a light source of a photographing light source based on the photometry information obtained by the photometry value calculation portion, the light intensity of the observation light source obtained in the measurement, and a correction value of the light intensity of the photographing light source.

Abstract: Method for determining the acceptance of progressive addition lenses of a wearer, the method comprising: a fusional vergence parameter providing step during which at least one fusional vergence parameter representing the fusional vergence of the wearer is provided, an acceptance determining step during which the value of the at least one fusional vergence parameter is compared to a predetermined threshold value so as to determine the probability of acceptance of progressive addition lens of the wearer.

Abstract: A reading meter system and method is provided for identifying the existence and position of text in visual media content (e.g., a document to be displayed (or being displayed) on a computer monitor or other display device) and determining if a subject has interacted with the text and/or the level of the subject's interaction with the text (e.g., whether the subject looked at the text, whether the subject read the text, whether the subject comprehended the text, whether the subject perceived and made sense of the text, and/or other levels of the subject's interaction with the text). The determination may, for example, be based on data generated from an eye tracking device. The reading meter system may be used alone and/or in connection with an emotional response tool (e.g., a software-based tool for determining the subject's emotional response to the text and/or other elements of the visual media content on which the text appears).

Abstract: A method for treating progression of a refractive disorder in a human eye. The method includes the steps of producing a first image on a retina of the human eye and producing a second image to generate a defocus.