Abstract: To provide a scattered light-type smoke detection apparatus in which internally scattered light in a smoke detection space can be suppressed to improve the S/N ratio.

Abstract: A particle detector including a chamber, a first aspirator, a sensor(s), a controller and clean air supply. The controller, when in a detecting mode, receives an indicative signal from the sensor and applies logic to the indicative signal to generate a further signal, and when in the purge mode controls substantial purging of the chamber of sample fluid with clean fluid from the clean fluid supply. The controller receives the indicative signal when the chamber is so purged and if necessary adjusts the logic in response thereto.

Abstract: A microassembled imaging cytometer includes a sensing location that undergoes relative motion with a cell. Light from a light source is focused by a focusing element to a plurality of focused illumination spots or lines at the sensing location, illuminating the cell as the cell traverses the sensing location. A collection lens collects light emanating from the cell and refocuses the collected light onto an array light sensor. The focusing element may include an array of microlenses having spherical or aspheric surfaces. The system may include a processing unit that constructs a digital image of the cell based at least in part on signals produced by the array light sensor indicating the intensity and distribution of light falling on the array light sensor. The system may characterize cells using light emanating from the cells by fluorescence.

Abstract: Methods and apparatus to capture images of fluorescence generated by ionizing radiation and determine a position of a beam of ionizing radiation generating the fluorescence from the captured images. In one embodiment, the fluorescence is the result of ionization and recombination of nitrogen in air.

Abstract: A photoelectric smoke sensor capable of detecting smoke with high accuracy is provided. The present invention relates to the photoelectric smoke sensor which detects smoke flowing into a housing by light. The present invention is provided with a light emitting element provided by being faced with a detection region in the housing and emitting inspection light to the detection region, a light receiving element provided at a position shifted from an optical path of the inspection light of the light emitting element by being faced with the detection region and receiving diffused light which is the inspection light having hit the smoke and diffused, so as to detect the smoke, and a reflecting member provided in the housing and deflecting and reflecting the inspection light emitted from the light emitting element so as not to enter the light receiving element.

Abstract: Although a more accurate estimate of a person's risk of cardiovascular disease can be made on the basis of the number of lipoprotein particles per unit volume in the person's blood, current methods all rely on measuring the mass of lipoprotein cholesterol per unit volume. It has been discovered that a rapid and accurate lipoprotein particle count can be obtained by photometry. A method and apparatus are provided for measuring the number of lipoprotein particles in a sample using photometry.

Abstract: The invention relates to methods and apparatus for detecting properties of suspended particles. Embodiments disclosed include an optical instrument (200) for detecting properties of a sample, comprising: a sample cell (103) for holding a sample of a particulate dispersion; a coherent light source (101) configured to illuminate the sample in the sample cell (103); a light intensity detector (104, 106) positioned to receive and measure an intensity of light from the coherent light source (101) elastically scattered by the sample in the sample cell (103); and a spectral light detector (212) positioned and configured to receive and measure a range of wavelengths of light from the coherent radiation source (101) inelastically scattered by the sample in the sample cell (103).

Abstract: A scattered radiation fire detector having radiation sources of different wavelengths and a scattered radiation sensor, which are arranged and formed so that their optical axes are directed at a common centre of a scattering volume. A sensor unit is furthermore formed to register forward scattering I1(?1,fwd) of a first radiation source, forward scattering I2(?2,fwd) of a second radiation source and backward scattering I3(?1,bwd) of a further first radiation source, to calculate scattered radiation intensity quotients Q1=I1(?1,fwd)/I2(?2,fwd), Q2=I1(?1,fwd)/I3(?1,bwd) and Q3=I2(?2,fwd)/I3(?1,bwd) and to detect the existence of a fire situation using the scattered radiation intensity quotients.

Abstract: A particle detection system (100), such as an active video smoke detection system, includes at least one illumination means (102) for directing a beam (106) of radiation through at least part of the air volume being monitored (110), an image sensor (104) is positioned to capture images of at least part of a beam (106) from illumination means (102); and means to analyze (107) the captured images to detect the presence of particles within the volume. At least 29 different aspects are described for improving the sensitivity, usability, and robustness of particle detection. These include, for example, configuring illumination means (102) to create a curtain of light or a rapidly-scanned beam across the air volume (110), and configuring a reflector to steer or change direction of a beam reflected from illumination means (102).

Abstract: The invention relates to a flow cytometer system and method to apply a gain to data measurements to improve the display of the data measurements. The method for applying a gain to data detected in a flow cytometer, involves obtaining measurements from a detector in a flow cytometer, applying a gain to the measurements to produce shifted measurements to allow for improved display of the shifted measurements while maintaining the relationship between data points of the shifted measurements and displaying the shifted measurements on a display.

Abstract: The invention relates to a particle detector including a substrate made of a semiconductor material, in which at least one through-cavity is formed, defined by an input section and an output section, wherein the input section thereof is to be connected to an airflow source, the substrate supporting: an optical means including at least one laser source, and at least one waveguide connected to the at least one laser source and leading into the vicinity of the output section of the cavity; and a photodetector located near the output section of the cavity and offset relative to the optical axis of the optical means.

Abstract: In accordance with certain embodiments, a smoke detector comprises a housing, a light source, one or more light detectors, and an evaluation circuit for determining the presence of smoke particles outside the housing based on light emitted from and reflected back into the housing, as well as light emitted within the housing without emission therefrom.

Abstract: The present invention describes a low-cost, portable multi-parameter, turbidity sensor based on optical fiber. The sensor quantifies the transmission and scattering of radiation (nephelometry) in a fluid through radiation emission in two or more wavelengths. Inc invention can be used to estimate concentration of suspended sediments, to distinguish the type of sediment based on color, to distinguish different particle-size classes, and to identify and determine the concentrations of different suspended-sediment fractions. The sensor comprises the following elements: radiation emitter of two or more wavelengths (2), a radiation receiver to measure the transmitted radiation. (2), a radiation receiver to measure the scattered radiation (3), and an inner space (4) of the measurement unit containing the fluid being evaluated.

Abstract: The invention relates to a method for estimating the amount of entities deposited on microparticles in suspension in a solution, and also to an associated device. The method comprises the following steps: (a) the solution is illuminated with a light source; (b) an optical signal formed by the scattering, in the solution, of the illuminating light is detected; (c) the optical signal obtained in step (b) is analyzed in order to obtain an indicator relating to this signal; (d) the indicator obtained in step (c) is compared with a reference indicator, obtained for a reference solution, the comparison making it possible to estimate the amount of entities deposited on the microparticles.

Abstract: A particle analyzer comprises a light source, a flow cell, an irradiating optical system, and a light receiving optical system. The light receiving optical system comprises a light focusing lens system which includes a light focusing lens configured to focus forward scattered light from the particles, a light receiving member configured to receive the forward scattered light, and a beam stopper. The beam stopper is provided in the light path between the light focusing lens system and the light receiving member. The light focusing lens has an aspheric lens form. The light focusing lens system is configured such that the focal distance of the forward scattered light through the central area which includes the optical axis is longer than the focal distance of the forward scattered light through the peripheral area outside the central area.

Abstract: A turbidity sensor and a method for determining at least one physical, chemical and/or biological measured variable of process automation in a medium by means of at least one optical sensor, comprising the steps of sending transmission signals into the medium, wherein the transmission signals are converted into received signals by interaction with, especially by scattering from, the medium as a function of the measured variable; receiving the received signals; and converting the received signals into the measured variable as a function of environmental conditions at the location of installation and, adjusting the sensor based on a calibration graph corresponding to environmental conditions at the location of installation.

Abstract: An apparatus (10) for measuring the light scatter from a measured zone (12) is provided, the apparatus having a light transmitter (14) for transmitting a light beam (18) into the measured zone and having a light receiver (22) with a reception optics (24) for detecting light scattered in the measured zone (12), wherein an adjustment unit is provided to change between a measuring mode in which the optical axes of the light transmitter (14) and the reception optics (24) stand at an angle with respect to one another and intersect in the measured zone (12) and a test mode in which the optical axes of the light transmitter (14) and the reception optics (24) are aligned in parallel with one another, and wherein the light beam (18) successively sweeps over the reception optics (24) for recognizing contaminants.

Abstract: In accordance with certain embodiments, a smoke detector determines the presence of smoke particles outside its housing based on measurements of light detected at different wavelengths and corrected based on an ambient light level.

Abstract: An inspection method and an inspection device, or apparatus each capable of conducting composition analysis of a defect detected by elastic or stokes scattered light, an inspection surface or defect on the surface of the inspection surface, or a defect on the surface of the inspection object and its internal composition. A surface inspection method for optically detecting elastic or stokes scattering or inelastic or anti-stokes scattered light from inside the surface of the inspection object, for detecting existence of defects of the inspection object and features of the defects, for detecting positions of the detected defects on the surface of the inspection object, classifying and analyzing the detected defects in accordance with their features on the basis of the positions of the defects and the features of the defects or the classification result of the defects.

Abstract: Disclosed is a fine particle measurement apparatus including a light condensing unit that condenses irradiated light irradiated to a sample flow where fine particles pass through and directly propagates the light without scattering, and scattered light scattered by the fine particles to an optical receiver divided into a plurality of regions; a position controller that controls the relative positions of members of an optical path; and a control unit that detects positions of condensing spots of the irradiated light and the scattered light based on signal intensities of each region of the optical receiver, and controls the position controller such that the positions of the condensing spots of the irradiated light and the scattered light match with each other.

Abstract: A calibration device is described for calibrating a scatterometer, which is designed in particular for measuring a particle concentration in exhaust gases of motor vehicles. The calibration device has at least one scattering body which emits scattered light having a defined intensity and distribution when irradiated with a light beam, the scattering body having an emission surface for the scattered light, to which is assigned at least one light sensor for detecting the scattered light exiting the emission surface. A screening body having at least one screen opening through which the scattered light exits in the direction of the at least one light sensor is assigned to the emission surface of the scattering body.

Abstract: In an apparatus for measuring an optical characteristic of a sample, one object of the present invention is to provide an apparatus capable of measuring hemispherical total reflectance, hemispherical total transmittance, and light distribution, and to achieve a reduction in measurement time and an improvement in precision of the quantitative analysis of hemispherical total reflectance (transmittance). In a double ellipsoidal optical system which is an optical system in which one focal points of two ellipsoidal mirrors are positioned as a common focal point, and three focal points are aligned in a straight line, the double ellipsoidal optical system is composed of a partial ellipsoidal mirror 2, such as a quarter ellipsoidal mirror, and a belt-shape ellipsoidal mirror 1.

Abstract: A microparticle analysis apparatus includes at least: a detecting unit having one or a plurality of light sources and a plurality of photodetectors, configured to emit excitation light from the light sources, and to detect light emitted from microparticles on which the excitation light is irradiated, at the photodetectors; a first storage unit configured to store, for each microparticle, data detected at the photodetectors of the detecting unit based on detected time; and a second storage unit configured to store data relating to a particular microparticle of detected data stored in the first storage unit.

Abstract: A lid for multiwell plates, allowing improved optical measurement of liquid samples within its wells, while mitigating evaporation from said samples, is disclosed. A surface element protrudes from the bottom of the lid into the fluid within a well. The protruding element may be hollow or solid such that light directed into the element may act to capture or direct the beam while preventing backscatter from reaching one or more detectors. The protruding element may direct the beam from the well without requiring the beam to pass through a fluid/air interface. The angle and shape of the lid surfaces and/or light absorbing/blocking colorization may be employed to minimize or eliminate back reflection. Evaporation is controlled by physically capping the well with the lid, either sealing against the face at the top of the well or the inside surface of the well.

Abstract: Simultaneous Multiple Sample Light Scattering systems and methods can be used to for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces. among others, that create a polymer stress response used to characterize the polymer solution and stability.

Abstract: An optical system for acquiring fast spectra from spatially channel arrays includes a light source for producing a light beam that passes through the microfluidic chip or the channel to be monitored, one or more lenses or optical fibers for capturing the light from the light source after interaction with the particles or chemicals in the microfluidic channels, and one or more detectors. The detectors, which may include light amplifying elements, detect each light signal and transducer the light signal into an electronic signal. The electronic signals, each representing the intensity of an optical signal, pass from each detector to an electronic data acquisition system for analysis. The light amplifying element or elements may comprise an array of phototubes, a multianode phototube, or a multichannel plate based image intensifier coupled to an array of photodiode detectors.

Abstract: A method and apparatus for the illumination of a sample are disclosed. An imaging illumination light source is directed to pass through an absorbing/transmitting structure in order to illuminate the sample and any containing vessel. A diffuser may aid in properly dispersing the light from the imaging illumination source. A light sensitive detector such as a camera records an image therefrom. The beam from a light scattering source is directed through the sample and any containing vessel, and upon exiting the sample/vessel, impinges upon the absorbing/transmitting structure selected to absorb at the wavelength of the light scattering source. Scattered light from the sample is collected by a photo detector. Methods of use for the novel lighting system are also disclosed.

Abstract: This invention provides new methods and apparatus for rapidly analyzing single bioparticles to assess their material condition and health status. The methods are enabled by a resonant cavity to measure optical properties related to the bioparticle size and refractive index. Refractive index measurements are useful for determining material properties and biomolecular composition of the bioparticle. These properties and composition are dependent on the health state of the bioparticle. Thus, measured optical properties can be used to differentiate normal (healthy) and abnormal (diseased) states of bioparticles derived from cells or tissues. The methods are illustrated with data obtained from a resonator with a gain medium.

Abstract: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.

Abstract: The invention relates to a method for measuring the scattered light (L2) of particles (P, PK) in a measuring medium (F), wherein a measuring container (1) is supplied with the measuring medium (F) and incident light (L1) is shone through the measuring medium (F) at least in some regions over a certain path length (1) and in a certain direction and the light (L2) scattered from the incident light (L1) is measured within a certain angle range (?). It is provided according to the invention that the incident light (L1) is guided parallel to a longitudinal axis (S) of the measuring container (1). By these measures, known methods can be improved and it is readily possible to use the invention even for very small measuring volumes of the measuring medium (F) with the associated small dimensions of the measuring container (1).

Abstract: A device (FIG. 2) that uses light to detect particles in fluid is disclosed. The device incorporates a lens and reflector on a flow cell to increase the numerical aperture of a subsequent light collection system without any increase in spherical aberration.

Abstract: Systems and methods are described for measuring a tissue parameter such as % StO2 in a tissue sample. One such method includes receiving first and second scattered light intensity signals at unique locations on a selected region of tissue from light injected into the region of tissue from a light source to identify a measured light attenuation data value. An electronic data store can be accessed that includes simulated light attenuation data determined from a mathematical tissue model at discrete points over a range of two or more tissue parameters, where the simulated light attenuation data are a function of one or more temperature-dependent light source spectra. The tissue parameter in the tissue sample can be determined by selecting a closest match between the measured light attenuation data and the simulated light attenuation data. An electronic signal representative of the determined tissue parameter can be sent to an output register.

Abstract: A sensor unit that includes at least one sensor configured to measure an ambient condition is described. The controller can be configured to receive instructions, to report a notice level when the controller determines that data measured by the at least one sensor fails a report threshold test corresponding to a report threshold value. The controller can also be configured to obtain a plurality of calibration measurements from the at least one sensor during a calibration period and to adjust the threshold based on the calibration measurements. The controller can be configured to compute a first threshold level corresponding to background noise and a second threshold level corresponding to sensor noise, and to compute the report threshold value from the second threshold. In one embodiment, the sensor unit adjusts one or more of the thresholds based on ambient temperature.

Abstract: A system and method for performing flow cytometry is disclosed wherein the alignment of the light source with respect to the sensing region of the fluid stream is continuously controlled using a feedback control loop. An imaging apparatus is provided that images the system along the optical axis, between the field stop and the sensing region. In an embodiment, the cytometer includes a field stop having an H-shaped aperture and light diverters over the ends of the aperture that divert a portion of the light to peripheral detectors.

Abstract: An apparatus for manipulating surface near-field light resulting from light emitted from a light source that passes through a scattering layer is disclosed. Also, a method of finding a phase of incident light to cause constructive interference at a target spot using light scattering to manipulate the surface near-field.

Abstract: A gas processing device such as an aerosol exposure monitor is configured for acquiring chronic data, acute data, or both simultaneously, and may include a pump and a noise dampening device. The noise dampening device may include an elastomeric membrane between an inlet chamber and an outlet chamber. In another aspect, an aerosol exposure monitor may include an impactor, a collection filter, and a nephelometer that includes a sample chamber integrated with an aerosol flow path associated with the impactor and collection filter.

Abstract: An image flow cytometer has a flow chamber with a flow channel formed therein to permit a microparticulate sample to flow through the flow channel. An irradiation optical system irradiates the sample in the channel with incident light in an irradiation spot smaller than a selected representative size, e.g., smaller than the sample. The system scans an irradiation position perpendicular to the flow direction of the sample. A detection optical system is opposed to the irradiation optical system through the flow chamber, or is off the optical axis of the incident light. The detection system detects a light intensity of resultant light from the flow chamber. A control unit detects the microparticulate sample according to a change of the light intensity of the resultant light detected by the detection optical system.

Abstract: In accordance with certain embodiments, a smoke detector determines the presence of smoke particles outside its housing based on measurements of light detected at different wavelengths and corrected based on an ambient light level.

Abstract: A measuring system for measuring absorption or scattering of a medium at a plurality of different wavelengths, whereby the measurements for the different wavelengths are performable as simultaneously and as accurately as possible. The measuring system comprises: a measuring chamber; a transmitting unit, which sends light of its respective wavelength into the measuring chamber; a control, which operates each light source with a different time modulation of transmission intensity for each wavelength; a detector for measuring a total radiation intensity. The total radiation intensity corresponds to a superpositioning of each intensity portion striking the detector for each wavelength; and a signal processing system, which determines for each of the wavelengths the associated intensity portion based on the total radiation intensity measured by detector and the modulations.

Abstract: The embodiments of the present invention disclose a vacuum cell-assembling device and a cell-assembling method. The vacuum cell-assembling device comprises: an upper substrate, a signal processing apparatus, and a lower substrate provided opposite to the upper substrate, wherein the upper substrate is provided with a light-emitting apparatus thereon, and the lower substrate is provided a photosensitive receiving element array thereon, and the photosensitive receiving element array is connected with the signal processing apparatus, and the signal processing apparatus is adapted for converting the electrical signals from the photosensitive receiving element array to a liquid crystal diffusion-simulation image.

Abstract: The present invention relates to a method for determining at least one gas condition at a location in a combustion chamber of a power plant or a combined heat and power plant by means of a laser pulse. The method comprises emitting (S1) the laser pulse into the chamber, determining (S2) a first point of time at which the laser pulse is emitted into the chamber, detecting (S3) laser light backscattered by gas molecules at the location in the chamber, determining (S4) a second point of time at which the laser light backscattered by the gas molecules is detected, determining (S5) the location based on the first point of time, the second point of time, and a pulse length of the laser pulse, and determining (S5) the at least one gas condition at the location based on at least one characteristic of the backscattered laser light detected at the second point of time. A gas measurement system and a combustion system are also presented herein.

Abstract: A chip-scale optical approach to performing multi-target detection is based on molecular biosensing using fiber-optic based fluorescence or light scattering detection in liquid-core waveguides. Multiplexing methods are capable of registering individual nucleic acids and other optically responsive particles, and are ideal for amplification-free detection in combination with the single molecule sensitivity of optofluidic chips. This approach overcomes a critical barrier to introducing a new integrated technology for amplification-free molecular diagnostic detection. Specific examples of liquid-core optical waveguides and multi-mode interferometers are described; however, they can be implemented in a number of different ways as long as a series of excitation spots is created whose spacing varies with the excitation wavelength.

Abstract: The invention relates to a particle detector including a substrate (10, 30, 40) made of a semiconductor material, in which at least one through-cavity (11, 31, 41) is formed, defined by an input section (110) and an output section (111), wherein the input section thereof is to be connected to an airflow source, said substrate supporting: an optical means including at least one laser source (12, 32, 42), and at least one waveguide (13, 33, 43) connected to said at least one laser source and leading into the vicinity of the output section of said cavity; and photodetector means (14, 34, 44) located near the output section of said cavity and offset relative to the optical axis of the optical means.

Abstract: An optical interrogation system, e.g., an OFDR-based system, measures local changes of index of refraction of a medium contained within a light guiding tube and includes an optical interferometric interrogator, optical detection circuitry, and a data processor. The data processor initiates a sweep of the light source and guide light from an interrogating light source into a medium contained by a tube which restricts movement of particles provided into the tube, where the medium is subjected to a driving force that overcomes resistance to movement of particles through the medium in the tube. The optical interferometric interrogator provides an optical interference pattern associated with a group of particles having moved in the tube as a result of the driving force. Based on the optical interference pattern, the data processor identifies a current location of the group of particles in the tube.

Abstract: A particle analyzer comprises a light source, a flow cell, an irradiating optical system, and a light receiving optical system. The light receiving optical system comprises a light focusing lens system which includes a light focusing lens configured to focus forward scattered light from the particles, a light receiving member configured to receive the forward scattered light, and a beam stopper. The beam stopper is provided in the light path between the light focusing lens system and the light receiving member. The light focusing lens has an aspheric lens form. The light focusing lens system is configured such that the focal distance of the forward scattered light through the central area which includes the optical axis is longer than the focal distance of the forward scattered light through the peripheral area outside the central area.

Abstract: An airborne, gas, or liquid particle sensor with a mixed-mode photo-amplifier front-end. The photo-amplifier uses pulse-height for the high-gain channel and integrates the pulse-energy for the low-gain channel to provide for a larger dynamic range for larger size particles.

Abstract: A chromatographic optical detection system includes an optical detector disposed to receive light scattered from a stream of particles and configured to convert the received light to an electrical signal; a signal-processing unit in signal communication with the optical detector to receive the electrical signal, and configured to convert the electrical signal to digital pulses and count the digital pulses to output a first signal corresponding to a number of particles detected in a time interval, and configured to integrate and digitize the electrical signal to output a second signal corresponding to the number of particles detected in the time interval; and a data station in signal communication with the signal-processing unit, and configured to select the first signal, if the number of particles detected in the time interval is less than a threshold criterion, and to select the second signal if the number of particles detected in the time interval exceeds the threshold criterion.

Abstract: Methods for using focused light scattering techniques for the optical sensing of biological particles suspended in a liquid medium are disclosed. The optical sensing enables one to characterize particles size and/or distribution in a given sample. This, in turn, allows one to identify the biological particles, determine their relative particle density, detect particle shedding, and identify particle aggregation. The methods are also useful in screening and optimizing drug candidates, evaluating the efficacy and dosage levels of such drugs, and in personalized medicine applications.

Abstract: A system and a method of measuring a particle's size in a select aerosol using the optical diameter of the particle to perform a mobility and/or aerodynamic diameter conversion without any knowledge about the particle's shape and its optical properties in the aerosol being characterized. In one example embodiment of the invention, the method includes generating a set of calibration data and finding the optimal refractive index and shape that best fits the calibration data. In addition, the method includes creating a new calibration curve that provides a mobility-equivalent or aerodynamic-equivalent diameter.

Abstract: A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.