Of Fluent Material Patents (Class 356/436)
  • Patent number: 11143589
    Abstract: A gas analysis system with an FTIR spectrometer preferably utilizes a long path gas cell, a narrow band detector, and an optical filter that narrows the detection region to measure hydrogen sulfide.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: October 12, 2021
    Assignee: MLS ACQ, Inc.
    Inventors: Martin L. Spartz, Anthony S. Bonanno, Kelly Renee McPartland
  • Patent number: 11137344
    Abstract: A fluid to be optically monitored may be optically mixed to modify the apparent color perceived by a colorimetric optical sensor device. The fluid is positioned within a fluid compartment of a vessel also including a contrast compartment adjacent to the fluid compartment. The contrast compartment is configured to have a contrast color with a known main wavelength that is different from the main wavelength of the fluid color. Light from a broadband light source of the colorimetric optical sensor device is reflected off of the vessel, with the received light being received by an optical spectrometer. The optical spectrometer analyzes the received light to determine a main wavelength of the received light, followed by a controller determining a characteristic of the fluid, which is based on the main wavelengths of the received light and the contrast color and the percentage of the vessel occupied by the fluid compartment.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: October 5, 2021
    Assignee: Fenwal, Inc.
    Inventors: Benjamin E. Kusters, Kyungyoon Min
  • Patent number: 11105953
    Abstract: A method and system can include positioning an optical waveguide along a wellbore, and launching one or more optical signals into the waveguide at one or more optical signal frequencies and during one or more time periods, thereby resulting in one or more backscattered signals being received by the receiver, which produces a trace for each of the one of more backscattered signals. Changing an environmental condition in the wellbore, generating additional backscattered light signals at one or more frequencies after the change. Comparing the traces generated before the condition change to those generated after the change, identifying a before trace and an after trace that are substantially equal to each other and identifying a frequency difference between these traces. The frequency difference can be used to determine the amount of change in the environmental condition that occurred when the environmental change event happened.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: August 31, 2021
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Wolfgang Hartmut Nitsche, Yenny Natali Martinez, David Andrew Barfoot, Michel Joseph LeBlanc, Jose R. Sierra, John Laureto Maida
  • Patent number: 11035707
    Abstract: An optical flow meter includes a substrate; a microchannel with a fluid receiver; a fluid transmitter; a fluid member with an optical interaction region; a photo interaction region; an analytical light path, such that analytical light interacts with an analyte in a photo interaction region subsequent to an interaction of a pre-analyte with activation light in an optical interaction region to produce analyte; and a detection light path disposed in the substrate, arranged at an oblique angle or right angle to the fluid member proximate to the photo interaction region, and that: receives the photoanalyte light from the photo interaction region; and communicates the photoanalyte light from the microchannel to a photodetector, the optical flow meter determines a flow rate of the analyte.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: June 15, 2021
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Gregory Alan Cooksey, Paul Nathan Patrone, Anthony Jose Kearsley
  • Patent number: 10921234
    Abstract: The present invention relates to methods and systems for image cytometry analysis, typically at low optical magnification, where analysis is based on detection of biological particles using UV bright field and optionally one or more sources of excitation light.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: February 16, 2021
    Assignee: CHEMOMETEC A/S
    Inventors: Martin Glensbjerg, Johan Holm, Søren Kjærulff, Frans Ejner Ravn Hansen
  • Patent number: 10906038
    Abstract: Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: February 2, 2021
    Assignee: Dropworks, Inc.
    Inventors: Christopher Michael Perkins, Matthew Ryan Dunn, Andrew Carl Larsen, Donna Kelley, Michael Barich, Kristopher Holub, Pin Kao
  • Patent number: 10906037
    Abstract: Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: February 2, 2021
    Assignee: Dropworks, Inc.
    Inventors: Christopher Michael Perkins, Matthew Ryan Dunn, Andrew Carl Larsen, Donna Kelley, Michael Barich, Kristopher Holub, Pin Kao
  • Patent number: 10900837
    Abstract: A compact mmW spectroscopy cell system for detecting volatile organic compounds (compounds) in a gas. The system includes a gas collection chamber, an input buffer cavity for receiving the gas from the gas collection chamber, pumping devices to pass the gas from the buffer cavity to an absorption cell and maintain pressure, and a transceiver connected to the cell. The transceiver interrogates the absorption cell filled with the gas by passing a high frequency electromagnetic signal and sweeping the signal to generate an absorption spectra which is compared to a spectroscopy database for detecting the compounds in the gas. The absorption cell, collection chambers, and pumping devices are fabricated with standard CMOS processing techniques at chip and wafer scale. The transceiver bonded to the absorption cell with chip scale integration.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: January 26, 2021
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Adam Joseph Fruehling, Juan Alejandro Herbsommer, Argyrios Dellis
  • Patent number: 10901223
    Abstract: A virtual image generation system for use by an end user comprises a projection subsystem configured for generating a collimated light beam, and a display configured emitting light rays in response to the collimated light beam to display a pixel of an image frame to the end user. The pixel has a location encoded with angles of the emitted light rays. The virtual image generation system further comprises a sensing assembly configured for sensing at least one parameter indicative of at least one of the emitted light ray angles, and a control subsystem configured for generating image data defining a location of the pixel, and controlling an angle of the light beam relative to the display based on the defined location of the pixel and the sensed parameter(s).
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: January 26, 2021
    Assignee: Magic Leap, Inc.
    Inventors: Ivan L. Yeoh, Lionel Ernest Edwin, Robert Dale Tekolste
  • Patent number: 10866233
    Abstract: An analysis device includes a turntable, an optical pickup, and a controller. The turntable holds a specimen analysis disc having reaction regions on which nanoparticles binding to substances to be detected are captured. The optical pickup emits laser light to each reaction region, receives a reflected light from each reaction region, and generates a light reception level signal. The controller sequentially generates a plurality of measurement gate signals for counting the number of the nanoparticles captured on each reaction region, counts the number of the nanoparticles of each of the measurement gate signals based on the light reception level signal, specifies a measurement gate section in each reaction region according to a measurement result per measurement gate signal, and adds up the number of the nanoparticles of the respective measurement gate signals in the measurement gate section.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: December 15, 2020
    Assignee: JVC KENWOOD CORPORATION
    Inventors: Shigehiko Iwama, Makoto Itonaga, Yuichi Hasegawa, Koji Tsujita, Masayuki Ono
  • Patent number: 10866395
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: December 15, 2020
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Patent number: 10823714
    Abstract: A mass spectrometry system having a simplified control interface includes a processor and a memory. The memory includes instructions that when executed cause the processor to perform the steps of providing a user interface including a plurality of adjustment elements for adjusting at least one results effective parameter and at least one sample descriptive parameter; determining a plurality of instrument control parameters based on the at least one results effective parameter and the at least one sample descriptive parameter; and analyzing a sample while operating according to the plurality of instrument control parameters.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: November 3, 2020
    Assignee: THERMO FINNIGAN LLC
    Inventors: Joshua T. Maze, Scott T. Quarmby
  • Patent number: 10730052
    Abstract: There are provided an apparatus capable of treating biological particles in a sterile state, and a treatment apparatus. An apparatus for forming a liquid flow including biological particles includes: a chamber member; a sample liquid supply portion; a sheath liquid supply portion; and a vibrating electrode member. The chamber member includes a chamber and a flow cell extending from an interior to an exterior of the chamber. The sample liquid supply portion is configured to supply a sample liquid including the biological particles into the chamber. The sheath liquid supply portion is configured to supply a sheath liquid into the chamber. The vibrating electrode member extends from the interior to the exterior of the chamber, is made of an electrically conductive material, and is configured to be capable of supplying an electric charge to the sheath liquid and the sample liquid in the chamber and propagating an ultrasonic vibration.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: August 4, 2020
    Assignee: Allied Flow, Inc.
    Inventor: Masahiko Kanda
  • Patent number: 10724919
    Abstract: System and method of quantifying a gas leak in a specified field of view are disclosed. The system may comprise a cooled detector and two interchangeable band-pass non-cooled filters. A first non-cooled band-pass filter transmits electromagnetic radiation in a first spectral band that coincides with a non-transparent leaking gas spectral band. A second non-cooled band-pass filter transmits only electromagnetic radiation in a second spectral band which coincides with a transparent leaking gas spectral band. The system may comprise a quantification unit arranged to process the images generated by the cooled detector to thereby determine, based on the images thereof, a flowrate of the leaking gas in the specified field of view. The system may comprise a detection unit arranged to determine, based on alternately generated multiple first spectral band images and multiple second spectral band images, a gas leak in the specified field of view.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: July 28, 2020
    Assignee: OPGAL Optronic Industries Ltd.
    Inventors: Ernest Grimberg, Gil Abramovich, Omer Yanai
  • Patent number: 10670811
    Abstract: Embodiments of the present invention relate to a microring resonator control method and apparatus. The method includes: receiving an instruction, where the instruction is used to configure an operating wavelength of a microring resonator; determining whether the operating wavelength of the microring resonator is less than or equal to a center wavelength of a channel spectrum; and when the operating wavelength of the microring resonator is less than or equal to the center wavelength of the channel spectrum, configuring thermode power of the microring resonator based on a spacing between the operating wavelength and a first wavelength; or when the operating wavelength of the microring resonator is greater than the center wavelength of the channel spectrum, configuring thermode power of the microring resonator based on a spacing between the operating wavelength and a second wavelength.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: June 2, 2020
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventor: Xin Tu
  • Patent number: 10649218
    Abstract: A virtual image generation system for use by an end user comprises a projection subsystem configured for generating a collimated light beam, and a display configured emitting light rays in response to the collimated light beam to display a pixel of an image frame to the end user. The pixel has a location encoded with angles of the emitted light rays. The virtual image generation system further comprises a sensing assembly configured for sensing at least one parameter indicative of at least one of the emitted light ray angles, and a control subsystem configured for generating image data defining a location of the pixel, and controlling an angle of the light beam relative to the display based on the defined location of the pixel and the sensed parameter(s).
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: May 12, 2020
    Assignee: MAGIC LEAP, INC.
    Inventors: Ivan L. Yeoh, Lionel Ernest Edwin, Robert Dale Tekolste
  • Patent number: 10634616
    Abstract: An optical immersion probe assembly with an alignment mechanism is described. The alignment mechanism ensures that proper alignment is achieved between an optical fiber head and an optical immersion probe whenever the optical immersion probe is coupled to the optical fiber head. The alignment mechanism may include a notch defined in a portion of a first annular end surface of the optical fiber head, and a projection on a periphery of the optical immersion probe. The projection on the probe may be positioned a distance from a second annular end surface of the optical immersion probe, and sized to be received within the notch of the optical fiber head. Also described herein are techniques and processes for manufacturing the components of an optical immersion probe assembly, and for assembling the optical immersion probe assembly.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: April 28, 2020
    Assignee: MarqMetrix, Inc.
    Inventors: Brian James Marquardt, Giora Proskurowski, Alex McNeill
  • Patent number: 10591413
    Abstract: A fluid analyzer includes a substrate, a quantum cascade laser formed on a surface of the substrate and including a first light-emitting surface and a second light-emitting surface facing each other in a predetermined direction parallel to the surface, a quantum cascade detector formed on the surface and including the same layer structure as the quantum cascade laser and a light incident surface facing the second light-emitting surface in the predetermined direction, and an optical element disposed on an optical path of light emitted from the first light-emitting surface across an inspection region in which a fluid to be analyzed is to be disposed and reflecting the light to feed the light back to the first light-emitting surface.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: March 17, 2020
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Tatsuo Dougakiuchi, Akio Ito, Kazuue Fujita, Tadataka Edamura
  • Patent number: 10591408
    Abstract: A flow cell analyzes a fluid sample. A flow cell body contains a reference material and includes at least one hollow chamber to contain the fluid sample. Opposing surfaces of the flow cell body each have at least one transparent portion thereof. An optical path for light traversing through the flow cell body is defined in part by the transparent portions. A switching mechanism adjusts the amount of the reference material in the optical path to effect switching of the flow cell between a reference measurement state and a fluid sample measurement state. The reference measurement state corresponds to a first light intensity measurement and the fluid sample measurement state corresponds to a second light intensity measurement.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: March 17, 2020
    Assignee: CI SYSTEMS (ISRAEL) LTD.
    Inventor: Yoram Naor
  • Patent number: 10527606
    Abstract: Devices and methods are provided for breath gas analysis when determining the difference in the concentrations of at least one gas in the exhaled breathing air on the one hand and in the ambient air on the other hand. The device may include at least one gas sensor, by means of which the concentration of a gas can be determined, and a line system, through whose lines the exhaled air to be examined, the ambient air and a calibrating gas can be selectively pumped to the gas sensor. The method may include feeding ambient air; feeding calibrating gas to the gas sensor; feeding exhaled air to the gas sensor; feeding calibrating gas to the gas sensor again; and feeding exhaled air to the gas sensor again.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: January 7, 2020
    Assignee: VYAIRE MEDICAL GMBH
    Inventor: Juergen Reinstaedtler
  • Patent number: 10520737
    Abstract: A virtual image generation system for use by an end user comprises a projection subsystem configured for generating a collimated light beam, and a display configured emitting light rays in response to the collimated light beam to display a pixel of an image frame to the end user. The pixel has a location encoded with angles of the emitted light rays. The virtual image generation system further comprises a sensing assembly configured for sensing at least one parameter indicative of at least one of the emitted light ray angles, and a control subsystem configured for generating image data defining a location of the pixel, and controlling an angle of the light beam relative to the display based on the defined location of the pixel and the sensed parameter(s).
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: December 31, 2019
    Assignee: Magic Leap, Inc.
    Inventors: Ivan L. Yeoh, Lionel Ernest Edwin, Robert Dale Tekolste
  • Patent number: 10520711
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: December 31, 2019
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Patent number: 10481075
    Abstract: A microorganism evaluation system comprising a viewing section for image acquisition, the viewing section comprising a viewing port configured to accommodate a fluid flow, at least one independently controlled imaging light source operably installed in the viewing section and configured to selectively illuminate the viewing port, and at least one independently controlled light stimulation device operably installed in the viewing section and configured to selectively emit light for invoking a motile response in a microorganism within the fluid flow in the viewing port, whereby the system synchronizes illumination of the at least one imaging light source and the at least one light stimulation device of the viewing section.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: November 19, 2019
    Assignee: SoBru Solutions, Inc.
    Inventor: John Miles Brubacher
  • Patent number: 10422740
    Abstract: Devices, methods, systems, and computer-readable media for a dual wavelength source gas sensor are described herein. One or more embodiments include a gas sensor, comprising: a dual wavelength source to transmit a first wavelength and a second wavelength via an optical path, wherein a gas is present through the optical path, a detector to receive the first wavelength and the second wavelength via the optical path, and a computing device coupled to the detector to determine an determine a signal intensity for the first wavelength and the second wavelength.
    Type: Grant
    Filed: July 5, 2016
    Date of Patent: September 24, 2019
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Teresa M. Marta, Martin Willett, Bernard Fritz
  • Patent number: 10359634
    Abstract: A virtual image generation system for use by an end user comprises a projection subsystem configured for generating a collimated light beam, and a display configured emitting light rays in response to the collimated light beam to display a pixel of an image frame to the end user. The pixel has a location encoded with angles of the emitted light rays. The virtual image generation system further comprises a sensing assembly configured for sensing at least one parameter indicative of at least one of the emitted light ray angles, and a control subsystem configured for generating image data defining a location of the pixel, and controlling an angle of the light beam relative to the display based on the defined location of the pixel and the sensed parameter(s).
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: July 23, 2019
    Assignee: Magic Leap, Inc.
    Inventors: Ivan L. Yeoh, Lionel Ernest Edwin, Robert Dale Tekolste
  • Patent number: 10345564
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: July 9, 2019
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Patent number: 10295473
    Abstract: Gas detector tubes may be used to determine a concentration of target gases in air. The gas detector tubes described may be read either by and optical reader or visually by the user. A gas detector tube reader having an optical reader capable of reading a length of stain, a color change and color density of a reagent in a gas detector tube. The gas detector tube may further comprise sensors for measuring the environmental conditions during sampling.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: May 21, 2019
    Assignee: Nextteq, LLC.
    Inventors: Bryan I. Truex, Gueorgui M. Mihaylov
  • Patent number: 10288545
    Abstract: A fluidics system for a flow cytometer is disclosed. In some examples, the system includes a junction disposed between a pump and a sample probe. In some examples, the pump is a peristaltic pump. A pulse-attenuation system is also disclosed. A method for removing gaps caused by pulsations in output data is also disclosed. A fluidics system and method for processing samples in parallel is also disclosed. A fluidic system for a flow cytometer that includes an agitator for agitating a sample is also disclosed. A sheath fluid transfer system of a fluidic system for a flow cytometer is also disclosed.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: May 14, 2019
    Assignee: Beckman Coulter, Inc.
    Inventors: Richard R. Martin, Todd Halvorson, Jeffrey J. Corpstein
  • Patent number: 10279141
    Abstract: A tub is configured to contain a supply of water and is configured to be inserted into a chamber of a humidifier. The tub includes a tub base configured to contain the supply of water. The tub also includes a tub lid and a flow plate provided between the tub base and the tub lid. The flow plate includes a water level indicator configured to indicate a level of the supply of water in the tub base. In addition, the water level indicator includes a generally rectangular portion and a generally triangular portion.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: May 7, 2019
    Assignee: ResMed Limited
    Inventors: Alexander Virr, Andrew Roderick Bath, Nathan John Row, Dan Kao, Phoebe Katherine Hill, Nicholas Andrew Earl, Hargopal Verma, Junning Chen
  • Patent number: 10280457
    Abstract: This invention provides substrates for use in various applications, including single-molecule analytical reactions. Methods for propagating optical energy within a substrate are provided. Devices comprising waveguide substrates and dielectric omnidirectional reflectors are provided. Waveguide substrates with improved uniformity of optical energy intensity across one or more waveguides and enhanced waveguide illumination efficiency within an analytic detection region of the arrays are provided.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: May 7, 2019
    Assignee: Pacific Biosciences of California, Inc.
    Inventors: Cheng Frank Zhong, Paul Lundquist, Mathieu Foquet, Jonas Korlach, Hovig Bayandorian
  • Patent number: 10234377
    Abstract: Described is a system for remote analysis of spectral data. A set of measured spectral mixtures are separated using a blind demixing process, resulting in demixed outputs. A demixed output is selected for further processing, and a spectral library is selected from a set of spectral libraries that is specialized for the selected demixed output. Individual components in the selected demixed output are classified via a non-blind demixing process using the selected spectral library. Trace chemical residues are detected in the set of measured spectral mixtures.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: March 19, 2019
    Assignee: HRL Laboratories, LLC
    Inventors: Yuri Owechko, Shankar R. Rao
  • Patent number: 10227970
    Abstract: First piston position data of a piston in a displacement unit is obtained based on an output signal from a sensor associated with the displacement unit, the output signal being dependent upon a physical position of the piston in the displacement unit. Second piston position data of the piston in the displacement unit is obtained based on data indicative of a number of revolutions of a hydraulic motor in a hydraulic system, the hydraulic system being operable to drive the piston of the displacement unit. Based on the second piston position data, a flow rate of a fluid pumped by the displacement unit is estimated. A system correction factor is generated based on the first piston position data and the second piston position data. The estimated flow rate is adjusted based on the system correction factor.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: March 12, 2019
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Adriaan Gisolf, Youxiang Zuo, Yi Chen
  • Patent number: 10151640
    Abstract: A light beam measurement device includes: a polarization measurement unit including a first measurement beam splitter provided on an optical path of a laser beam and configured to measure a polarization state of the laser beam having been partially reflected by the first measurement beam splitter; a beam profile measurement unit including a second measurement beam splitter provided on the optical path of the laser beam and configured to measure a beam profile of the laser beam having been partially reflected by the second measurement beam splitter; and a laser beam-directional stability measurement unit configured to measure a stability in a traveling direction of the laser beam, while the first measurement beam splitter and the second measurement beam splitter are made of a material containing CaF2.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: December 11, 2018
    Assignee: Gigaphoton Inc.
    Inventors: Masato Moriya, Osamu Wakabayashi, Yoshinobu Watabe
  • Patent number: 10146215
    Abstract: A method for monitoring a process in a semiconductor processing facility and a monitor system are provided. A plurality of wafers are processed according to a process. Data on the processing is collected, and the collecting includes, for each wafer of the plurality of wafers, determining that a processing event has occurred, and recording a time associated with the processing event. An amount of time between the recorded times is calculated for consecutively processed wafers. A set of control limits for the process is determined based on the calculated amounts of time. The set of control limits define a range of acceptable values for the amount of time. Second wafers are processed according to the process. A problem in the processing of the second wafers is identified based on the set of control limits. The problem is identified as the second wafers are being processed.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: December 4, 2018
    Assignee: Taiwan Semiconductor Manufacturing Company Limited
    Inventors: Chih-Wei Huang, Feng-Ning Lee
  • Patent number: 10126709
    Abstract: Embodiments described herein relate to lens-free imaging. One example embodiment may include a lens-free imaging device for imaging a moving sample. The lens-free imaging device may include a radiation source configured to emit a set of at least two different wavelengths towards the moving sample. The lens-free imaging device is configured to image samples for which a spectral response does not substantially vary for a set of at least two different wavelengths. The lens-free imaging device may also include a line scanner configured to obtain a line scan per wavelength emitted by the radiation source and reflected by, scattered by, or transmitted through the moving sample. The line scanner is configured to regularly obtain a line scan per wavelength. Either the radiation source or the line scanner is configured to isolate data of the at least two different wavelengths.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: November 13, 2018
    Assignee: IMEC VZW
    Inventors: Richard Stahl, Murali Jayapala, Andy Lambrechts, Geert Vanmeerbeeck
  • Patent number: 10114203
    Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: October 30, 2018
    Assignee: Alentic Microscience Inc.
    Inventors: Alan Marc Fine, Peter Hodges Gregson
  • Patent number: 9970857
    Abstract: This disclosure provides automatic compensation methods, corresponding devices and a corresponding flow cytometer. The automatic compensation method includes: determining a base cell population and a reference cell population in the cell populations according to positions of the cell populations in a dot plot that needs to be compensated, where the base cell population is a double negative cell population and the reference cell population is a single positive cell population adjacent to the base cell population in a compensating direction (S10); calculating automatically a compensation value through a progressive approximation algorithm according to a position of the base cell population, and updating the dot plot with the compensation value, so that the position difference between the reference cell population and the base cell population both in the dot plot in the compensating direction is within a predetermined range (S16).
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: May 15, 2018
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Penghao Liu, Wenheng Guo, Youlin Liu, Jian Jin, Huawen Yan, Lifang Dong
  • Patent number: 9950941
    Abstract: An apparatus for measuring speed, the length and elongation of a molten glass gob travelling along a defined path includes at least two optical detectors. A mask having at least two openings through which light passes to each of the optical detectors is disposed adjacent the optical detectors. A lens receives light from the moving glass gob and focuses such light through the openings of the mask. Electronics are coupled to each of the optical detectors for determining the speed of the molten glass gob as a function of timing of light sensed at the optical detectors. In exemplary embodiments of the disclosure, the optical detectors is disposed within the image plane of the lens and comprise different portions of a single light sensing device.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: April 24, 2018
    Assignee: Owens-Brockway Glass Container Inc.
    Inventor: Karl C Johnston
  • Patent number: 9952150
    Abstract: The invention relates to a device for measuring the scattering of a sample. Said device includes at least one first and one second scattering receiver for capturing scattered rays from the sample; and at least one imaging element via which rays can reach the sample and from the sample to the scattering receiver. According to the invention, the first and second scattering receivers are arranged in a common flat or approximately spherically curved surface, which is oriented perpendicular to an optical axis of the imaging element. The first scattering receiver is designed and arranged to capture saturated scattered rays from the sample and the second scattering receiver is designed and arranged to capture linearly scattered rays from the sample.
    Type: Grant
    Filed: April 7, 2014
    Date of Patent: April 24, 2018
    Assignee: L.U.M. GMBH
    Inventors: Gert Sinn, Klaus-Henrik Mittenzwey
  • Patent number: 9921165
    Abstract: Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: March 20, 2018
    Assignees: Genalyte, Inc., The Board of Trustees of the University of Illinois
    Inventors: Ryan C. Bailey, Abraham J. Qavi, Jared T. Kindt, Ji-Yeon Byeon, Matthew S. Luchansky, Melinda S. McClellan, Adam L. Washburn, Tate Owen, Martin Anthony Gleeson, Lawrence C. Gunn, III
  • Patent number: 9891077
    Abstract: An apparatus is disclosed for capturing image information. The apparatus includes a waveguide having opposed planar input and output faces. A diffractive optical element (DOE) is formed across the waveguide. The DOE is configured to couple a portion of the light passing through the waveguide into the waveguide. The light coupled into the waveguide is directed via total internal reflection to an exit location on the waveguide. The apparatus further includes a light sensor having an input positioned adjacent the exit location of the waveguide to capture light exiting therefrom and generate output signals corresponding thereto. A processor determines the angle and position of the coupled light with respect to the input face of the waveguide based on the output signals.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: February 13, 2018
    Assignee: MAGIC LEAP, INC.
    Inventor: Adrian Kaehler
  • Patent number: 9846060
    Abstract: An optical sensor arrangement for measuring an observable, the arrangement including an optical resonance circuit including at least a first and a second optical resonator, each of the optical resonators including an entry port for coupling light into the optical resonator and a drop port for decoupling light from the optical resonator. The first and second resonator are configured such that only a portion of the first and second resonator detects the presence of the observable, a size of the portion of the first resonator being different from a size of the portion of the second resonator. The optical resonance circuit further configured to be coupled to a light generation circuit and to a detector unit for detecting light.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: December 19, 2017
    Assignee: Frauhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
    Inventors: Helmut Heidrich, Peter Lützow, Daniel Pergande
  • Patent number: 9818009
    Abstract: A multi-spectral scan camera and methods are presented. Light beams are emitted from a plurality of light sources comprising a plurality of spectral wavelengths respectively. The light beams from the light sources are scanned across a field of view at a plurality of respective angles using a scan mirror, and each of the spectral wavelengths are received at respective detectors.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: November 14, 2017
    Assignee: The Boeing Company
    Inventor: Douglas Jungwirth
  • Patent number: 9778165
    Abstract: Systems for collecting light (e.g., in a flow stream) are described. Light collection systems according to embodiments include: a mount having an orifice for receiving light, an adapter configured for attaching a camera to the mount and a fastener for attaching a lens to the distal end of the mount and a releasably attachable connecter that is configured for coupling to an orifice plate and an aligner that is configured to couple with an aligner on the mount and maintain optical alignment between the mount and connector. Methods for coupling a connector and a mount are also described. Systems and methods for measuring light emitted by a sample (e.g., in a flow stream) are also provided.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: October 3, 2017
    Assignee: Becton, Dickinson and Company
    Inventors: Gerrit Jan van den Engh, Brian R. Wadey, Veronica Lauren Kersten
  • Patent number: 9759651
    Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: September 12, 2017
    Assignee: Magellan Diagnostics, Inc.
    Inventors: Norman F. Sheppard, Jr., Gary Conrad Jensen
  • Patent number: 9727052
    Abstract: Technologies are described for monitoring characteristics of layers of integrated computational elements (ICEs) during fabrication using an in-situ spectrometer operated in step-scan mode in combination with lock-in or time-gated detection. As part of the step-scan mode, a wavelength selecting element of the spectrometer is discretely scanned to provide spectrally different instances of probe-light, such that each of the spectrally different instances of the probe-light is provided for a finite time interval. Additionally, an instance of the probe-light interacted during the finite time interval with the ICE layers includes a modulation that is being detected by the lock-in or time-gated detection over the finite time interval.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: August 8, 2017
    Assignee: Halliburton Energy Services, Inc.
    Inventors: James M Price, Aditya B. Nayak, David L. Perkins
  • Patent number: 9700054
    Abstract: The present invention relates to active and intelligent additives having hybrid characteristics, that are compatible with polymers, are thermally and mechanically stable, are capable of releasing electrons and/or photons in the presence of chemical compounds, specifically amino compounds, amide compounds, oxygen reducing compounds, water or vapors thereof. The active and intelligent additives incorporate themselves into polymer matrices allowing the obtainment of active and intelligent polymeric articles. These active and intelligent polymeric articles may act as inhibitors of growth of microorganisms and fungi, as well as indicators of the presence of gasses, either in the atmosphere or caused by the decomposition of foodstuffs, for example.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: July 11, 2017
    Assignees: Braskem S.A., Universidade Federal do Rio Grande do Sul
    Inventors: Edwin Moncada, João Henrique Zimnoch don Santos, Larissa Brentano Capeletti
  • Patent number: 9677995
    Abstract: A sample cell filling device for filling a sample cell to be used remotely from a polarimeter is provided. The filling device includes a liquid-sealed housing, light source and a diffuser viewing screen. The housing has a recess for receiving the sample cell, the sample cell having first and second optical windows at the respective ends. A light source transmits light from one optical window to the other optical window. A diffuser viewing screen receives light exiting from the sample cell such that light from the viewing screen can be observed by a user to determine the quality of the sample fill.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: June 13, 2017
    Assignee: RUDOLPH RESEARCH ANALYTICAL CORPORATION
    Inventors: Richard C. Spanier, Jeff Wagner
  • Patent number: 9675974
    Abstract: A vessel is for storing and monitoring a suspension of microscopic objects, which comprises a cap suitable for closing off the vessel. The cap includes a fluidics system, which includes an inlet and an outlet. The inlet and the outlet are arranged to be in an interior volume of the vessel when the cap is closing off the vessel. The cap also includes a measurement region for optical microscopy, which includes a sample region suitable for the suspension. The sample region is in fluid connection with the fluidics system. The cap also includes a pump suitable for inducing a flow in the fluidics system. A particular monitoring system and setup is for monitoring cells in a cell culture liquid.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: June 13, 2017
    Assignee: Ovizio Imaging Systems NV/SA
    Inventors: Serge Jooris, Philip Mathuis
  • Patent number: 9664500
    Abstract: Embodiments include optofluidic apparatus that may be used to detect and manipulate nanoparticles or biomolecules within a fluid. To achieve that result, the embodiments use a fluidic channel located over a substrate. Particular embodiments also use: (1) an optical waveguide located over the substrate and particularly within the fluidic channel along with an optical resonator that may or may not be located within fluidic channel; and also (2) a phase shifter component coupled to either the waveguide or the optical resonator. Additional embodiments use an MZI or an MZI with an optical resonator to further provide the phase shifter component coupled to one arm of the MZI or the optical resonator.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: May 30, 2017
    Assignee: CORNELL UNIVERSITY
    Inventors: Michelle D. Wang, Michal Lipson, Mohammad Soltani