Abstract: Photon generating substrates for light-directed oligonucleotide synthesis are disclosed. Light is generated within a solid-state stack that supports growing oligonucleotides. The light may be generated by microLEDs, a pass-through liquid crystal panel, or an LCoS system. Light passes through a transmissive layer on which growing oligonucleotides are attached. Patterning of the light is controlled by selective activation of the microLEDs or by selective control of the transparency of a liquid crystal layer. Photolabile blocking groups are selectively removed by exposure to patterned light emitted from the photon generating substrate.

Abstract: Provided are a sparger including: a disc-shaped body; and a first hole and a second hole having different sizes from each other provided in the body, wherein a diameter of the second hole is smaller than a diameter of the first hole, and a reactor comprising the sparger.

Abstract: The invention relates to a mixing device comprising at least one supply opening for at least one liquid and comprising at least one additional supply opening for at least one liquid curing or crosslinking agent. The liquid and/or the liquid curing or crosslinking agent is/are mixed with a gas. The mixing device also comprises a discharge opening for discharging a mixture, which can be produced in the mixing device, of the at least one liquid and the at least one liquid curing or crosslinking agent. A pressure holding device is provided for holding a specifiable pressure which is higher than the pressure at which the gas in the mixing device is foamed.

Abstract: Disclosed is a delivery device, kit, system, method, etc. for localized fusion of leaflets of a tissue valve, for example, a native heart valve, using an adhesive. The delivery device can have one or more capture features for capturing separate leaflets, for example, the anterior and posterior mitral leaflets. An applicator can be configured to apply a biocompatible adhesive between the captured leaflets, and one or more curing elements can be configured to cure the applied biocompatible adhesive. The kit can have the aforementioned delivery device, and the biocompatible adhesive used therewith. The method can include positioning the aforementioned delivery device adjacent the anterior and posterior mitral leaflets, capturing the mitral leaflets between the paddles of the delivery device, applying a biocompatible adhesive between the captured mitral leaflets via the applicator, and curing the applied biocompatible adhesive via the energy elements to locally fuse the mitral leaflets.

Abstract: The present disclosure relates to a super absorbent polymer and a preparation method of the same, which not only has excellent basic absorption performance, but also exhibits an improved absorption rate, and the like. The super absorbent polymer includes a base resin powder containing a first cross-linked polymer of a water-soluble ethylene-based unsaturated monomer having at least partially neutralized acidic groups; and a surface cross-linked layer containing a second cross-linked polymer in which the first cross-linked polymer is additionally cross-linked by a surface cross-linking agent on the base resin powder, wherein the super absorbent polymer contains less than 9.9% by number of super absorbent polymer particles having an aspect ratio, which is defined as shortest diameter/longest diameter of each super absorbent polymer particle, of less than 0.5, a vortex time is 5 to 55 seconds by a vortex method, and a surface tension is 50 to 80 mN/m.

Abstract: There is disclosed a fluid distribution system for distributing fluid from a single source to a plurality of downstream receptacles. The system has a distribution manifold with a single inlet and a plurality of outlets arrayed around a circumferential outer periphery. The outlets may be directed to the different receptacles which each have their own vent filter, or each receptacle connects back to the distribution manifold for common venting.

Abstract: A soundproof part that covers a compressor includes a side surface cover including two or more sound absorbing materials and two or more sound insulating materials, and configured to cover a side surface of the compressor. The two or more sound insulating materials include sound insulating materials having different specific gravities. The side surface cover is formed such that one sound absorbing material is disposed adjacent to the compressor, and a sound absorbing material and a sound insulating material are alternately arranged. The side surface cover is also formed such that as a distance from the compressor increases, the sound insulating materials having relatively lower specific gravities are disposed.

Abstract: A micro-interface strengthening reaction system and method for preparing polyethylene by using a solution process are provided. The system includes a pre-polymerization reactor and a polymerization reactor connected in sequence. The pre-polymerization reactor is provided with a pre-polymerization micro-interface generators, and the polymerization reactor is provided with a micro-interface generator. The system further includes a desolvation tower for removing solvents and impurities from the polyethylene product. A polyethylene inlet is disposed at a middle part of the desolvation tower, and the polyethylene inlet is connected with the flash tank bottom outlet. A nitrogen micro-interface generator for dispersing and breaking high-temperature nitrogen into micro-bubbles is disposed within the desolvation tower.

Abstract: Methods for separating gaseous components, such as unreacted hydrocarbon monomer and/or solvent, from polyolefin solids are provided. The methods include flowing a first stream including polyolefin solids and gaseous unreacted hydrocarbon monomer and/or solvent through a portion of a gas-solid separation vessel having a volume sufficient so that polyolefin solids present in the first stream have an increased residence time within the gas-solid separation vessel to separate gaseous unreacted hydrocarbon monomer and/or solvent from the polyolefin solids to produce a second stream including polyolefin solids substantially free of gaseous unreacted hydrocarbon monomer and/or solvent and a third stream including the gaseous unreacted hydrocarbon monomer and/or solvent. Systems for carrying out such methods are also provided.

Abstract: Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating inner loop reactor which utilize nonvertical pressure reduction zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.

Abstract: A gas turbine engine comprises a compressor section and a turbine section, the compressor section having a last compressor stage. High pressure cooling air is tapped from a location downstream of the last compressor stage and passed through a heat exchanger. Lower pressure air passes across the heat exchanger to cool the high pressure cooling air. A housing surrounds the compressor section and the turbine section and there being a space radially outwardly of the housing, and a mixing chamber received in the space radially outwardly of the housing, the mixing chamber receiving the high pressure cooling air downstream of the heat exchanger, and further receiving air at a temperature higher than a temperature of the high pressure cooling air downstream of the heat exchanger. Mixed air from the mixing chamber is returned into the housing and utilized to cool at least the turbine section.

Abstract: A pipette tip container comprising a pipette tip having a lumen extending between a proximal opening of a first diameter and a distal orifice of a second smaller diameter; a pellet arranged in the lumen of the pipette tip between said proximal opening and distal orifice, the second diameter being too narrow to let the pellet pass; and a retainer arranged between the pellet and the proximal opening and arranged to prevent the pellet from moving past the retainer in the lumen but to let fluid move past the retainer in the lumen; the retainer having a distal end such that a portion of its periphery does not contact the inner wall of the lumen, a proximal end such that a portion of its periphery maintains the retainer in the lumen by friction with the inner wall of the lumen; and a radial opening between the distal and proximal ends.

Abstract: This disclosure relates to a method and an apparatus for the delivery of a multi-component olefin polymerization catalyst to a polymerization reactor.

Abstract: There is disclosed a fluid distribution system for distributing fluid from a single source to a plurality of downstream receptacles. The system has a distribution manifold with a single inlet and a plurality of outlets arrayed around a circumferential outer periphery. The outlets may be directed to the different receptacles which each have their own vent filter, or each receptacle connects back to the distribution manifold for common venting.

Abstract: The present invention relates to an improvement for gas-phase olefin polymerization process having relatively high bed bulk density. The improvement involves the use of mixed external electron donors when polymerizing propylene in a gas-phase reactor having a polymer bed with a bulk density greater than 128 kg/m3, optionally with one or more comonomers, wherein the mixed electron donor system comprises at least a first external electron donor and a second external electron donor, and wherein the first external electron donor is a carboxylate compound.

Abstract: A process is described for introducing a catalyst into a polymerization zone by detecting one or a combination of (i) a change in a concentration of the catalyst in a catalyst feed stream upstream of the polymerization zone, (ii) a change in a concentration of monomer in the polymerization zone, and (iii) a change in a polymer production rate of the polymerization zone, adjusting a first catalyst flow rate of the catalyst in the catalyst feed stream to a second catalyst flow rate based on the one or a combination of (i), (ii), and (iii), and introducing the catalyst into the polymerization zone downstream of a location in the catalyst feed stream where the step of adjusting is performed. A catalyst injection system for carrying out such a process is also provided.

Abstract: A process for polymerizing or copolymerizing ethylenically unsaturated monomers at pressures in the range of from 110 MPa to 500 MPa in a production line comprising a continuously operated polymerization reactor, wherein the process comprises monitoring the surrounding of the production line with respect to an occurrence of a leakage of monomers or of reaction mixture by an IR point detector arrangement of at least three groups of IR point detectors which are capable of detecting hydrocarbons and the groups of IR point detectors are operating according to a voting logic and starting automatically an emergency pressure release program when a group of IR point detectors of the IR point detector arrangement detects the presence of hydrocarbons.

Abstract: Disclosed is a solution polymerization process, or, alternatively, a method of delivering powder catalysts to a solution polymerization reactor, comprising combining a homogeneous single-site catalyst precursor with ?-olefin monomers to form a polyolefin, wherein the homogeneous single-site catalyst precursor is in the form of (i) a dry powder, (ii) suspended in a aliphatic hydrocarbon solvent, or (iii) suspended in an oil or wax, wherein the homogeneous single-site catalyst precursor is at a concentration greater than 0.8 mmole/liter when suspended in the aliphatic hydrocarbon solvent prior to entering the solution polymerization reactor.

Abstract: Provided are a system for producing a polyolefin, a method of producing a polyolefin, and a method of producing a heterophasic propylene polymer material, each of which allows (i) a gel, to be contained in a molded product that is made of an obtained polyolefin, to be reduced and (ii) a polyolefin to be continuously produced stably.

Abstract: Systems and processes for controlling fouling in the manufacture of ethylene polymers and copolymers at high pressure. Disclosed is a high pressure polyethylene polymerization system comprising a reactor, a primary compressor, and a secondary compressor, the secondary compressor comprising: a) a first stage, wherein the first stage comprises at least two cylinders, and the discharge pipes of the at least two cylinders are fluidly connected by a first stage discharge cross-connect pipe; b) a second stage; c) an interstage; and d) a first cooler applied to the interstage piping starting at a location within 10 meters downstream of the first stage discharge cross-connect pipe.

Abstract: An integrated circuit includes two or more rows of heating elements, two or more columns of heating elements, and a plurality of sensing areas. Each sensing area is between two adjacent rows of the rows of heating elements, between two adjacent columns of the columns of heating elements, and includes a bio-sensing device and a temperature-sensing device.

Abstract: A process for polymerizing or copolymerizing ethylenically unsaturated monomers at pressures in the range of from 110 MPa to 500 MPa in a production line comprising a continuously operated polymerization reactor which is installed within a protective enclosure, wherein the production line is monitored with respect to an occurrence of a leakage of monomers or of reaction mixture and a water based deluge system, which provides droplets of a diameter in a range from 25 ?m to 20 mm to the enclosed area, is automatically started with a minimum flow rate of 10 L/min per m2 of enclosed area when a leakage of monomers or of reaction mixture is detected.

Abstract: The present invention concerns a method and an apparatus (10, 20) for a continuous preparation of organic peroxides, with the reactor comprising at least one flow channel (1, 1a, 1b) configured as a reaction zone; an inlet system (2) in fluid communication with a first end of the at least one flow channel and configured for introducing two or more substances or a combination of substances into the at least one flow channel; an outlet system (3) in fluid communication with a second end of the at least one flow channel, the second end being located downstream of the first end and the outlet system being configured for extracting a reaction product present at the second end; an oscillatory system (4, 5) configured for superimposing an oscillatory flow on the flow of substances passing through the at least one flow channel, the oscillatory being effected in at least a section of the at least one flow channel; and a controller configured to implement the method by controlling the inlet system to introduce, accordi

Abstract: The present invention relates to a melt transesterification process for the production of (co)polycarbonates from diaryl carbonates and cycloalkylidene diphenols, which process comprises the addition of a monohydroxyaryl compound in an amount of 5.0 to 20.0 wt.-%, based on the total mass of the reaction mixture. The invention further relates to a (co)polycarbonate obtained by the process.

Abstract: A process for polymerizing or copolymerizing ethylenically unsaturated monomers at pressures in the range of from 110 MPa to 500 MPa in a production line comprising a continuously operated polymerization reactor, wherein at least one of a pre-heater or pre-cooler, a polymerization reactor or a post reactor cooler is composed of tubes of a length from 5 m to 25 m which are flanged together, either directly or via bends, and the flanges are covered by a chimney construction, and wherein air is conveyed through the chimney construction and the air exiting the chimney construction is monitored with respect to the hydrocarbons concentration.

Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.

Abstract: Parallel reactor systems for synthesizing materials are disclosed. The reactor systems may be suitable for synthesizing materials produced from corrosive reagents. Methods for preparing materials by use of such parallel reactor systems are also disclosed.

Abstract: A process is described for introducing a catalyst into a polymerization zone by detecting one or a combination of (i) a change in a concentration of the catalyst in a catalyst feed stream upstream of the polymerization zone, (ii) a change in a concentration of monomer in the polymerization zone, and (iii) a change in a polymer production rate of the polymerization zone, adjusting a first catalyst flow rate of the catalyst in the catalyst feed stream to a second catalyst flow rate based on the one or a combination of (i), (ii), and (iii), and introducing the catalyst into the polymerization zone downstream of a location in the catalyst feed stream where the step of adjusting is performed. A catalyst injection system for carrying out such a process is also provided.

Abstract: This invention relates to a cartridge assembly tray for conducting automated biochemical tests, such as immunoassay tests. The tray comprises a base member, a hinged frame and a locking mechanism. The base member includes a plurality of slots within the base member. Each of the plurality of slots is to receive a test cartridge. The hinged frame is coupled to the base member. The hinged frame is capable to rotate to an opened position or a closed position. The hinged frame includes a horizontal push bar configured to apply a downward force to test cartridges received in the plurality of slots when the hinged frame is in the closed position. The locking mechanism is to lock the hinged frame in the closed position when the hinged frame rotates to the closed position.

Abstract: A single-component conductive adhesive with low hardness, and method of manufacture and use are provided. The conductive adhesive may include a resin composition, an organic solvent and nickel-coated graphite powder. The weight ratio of the resin composition to nickel-coated graphite powder may be 20%:80% or 40%:60%. The weight of the organic solvent may be 20-40% the weight of the resin composition. The resin composition may include 20-40% by weight of vinyl-terminated polydimethylsiloxane (PDMS), 5-15% by weight of H—Si polysiloxane oil, 0.05-0.15% by weight of polymerization inhibitor, and 0.1-1% by weight of encapsulated platinum complex.

Abstract: A robot, wherein the robot operates on the basis of a picked-up image of at least a part of a work space of the robot picked up by an image pickup section, and a transparent member is disposed between the robot and the work space of the robot.

Abstract: A system and method provide for high through put determination of agglutination states. The system includes a rotating table and multiple plate tilting stations. The system also includes one or more optical paths positioned to image entire plate arrays in tilted and/or untilted configurations. The system preferably includes image analysis software to analyze an image of an array of test wells and determine an agglutination state of each well based on the image analysis.

Abstract: The invention provides compositions, each comprising an ethylene/alpha-olefin interpolymer, which has a reduced level of a low density, low molecular weight oligomeric fraction, as indicated by an HCC value, as described herein, and reduced levels of inorganic content or lower Tm. The invention also provides processes for forming such interpolymers.

Abstract: The position controller for a pneumatic field device comprises a current-pressure transducer system having at least two I/P-transducers creating separate pneumatic control signals. Microelectronics creates at least two electrical control signals for the I/P-transducers. A pneumatic signal switching valve has at least two pneumatic inputs for the at least two pneumatic control signals, a pneumatic output for transferring a pneumatic control signal to a working chamber of the pneumatic field device and an electrical switch signal input. The pneumatic signal switch valve comprises a first switch position which blocks a first of the at least two pneumatic control signals and a second switch position which blocks a second of the pneumatic control signals.

Abstract: In the high pressure polymerization of ethylene homopolymers or copolymers, conditions in the high pressure recycle system may lead to the build-up of low molecular weight oligomers and waxes. Sequentially draining knock-out pots, located downstream of a high pressure separator, at regular intervals can reduce the build-up of low molecular weight oligomers and waxes during the high pressure polymerization of alpha olefins.

Abstract: A process for making a low density polymer in a polymerization reactor system, the process comprising polymerizing an olefin monomer, and optionally an olefin comonomer, in the presence of a diluent in a polymerization reactor to make a polymerization product slurry consisting of a liquid phase and a solid phase, wherein the solid phase comprises an olefin polymer having a density of between about 0.905 g/cm3 to about 0.945 g/cm3; and discharging the polymerization product slurry from the polymerization reactor through a continuous take-off valve to make a mixture further comprising a vapor phase. The mixture comprises a pressure less than a bubble point pressure of a component in the polymerization product slurry.

Abstract: Petrochemical complex containing an olefin monomer polymerization plant having at least one polymerization reactor and an optional degassing section. The polymerization reactor contains process hydrocarbons consisting of the monomer, the optional comonomer(s) and optionally at least one inert hydrocarbon diluent, together with aluminum containing compound(s). The polymerization plant includes liquid purge stream(s) which contain aluminum containing compounds and optionally polymer fines, together with accumulated hydrocarbons which are different from the process hydrocarbons and which are hydrocarbons containing at least 4 carbon atoms. The petrochemical complex also contains a multipurpose hydrocarbon treatment unit which separates the liquid purge stream(s) into one stream having substantially all of the aluminum containing compounds and optional polymer fines, and one stream containing the accumulated hydrocarbons.

Abstract: Process for the gas-phase polymerization of olefins in a fluidized bed reactor, by a) passing a fluidizing gas containing an olefin monomer through a fluidized bed of polymer particles in the presence of a polymerization catalyst, b) withdrawing a first gaseous stream containing solid particles from the reactor, c) passing the first gaseous stream to a gas/solids separator, separating solid particles, and forming a second gaseous stream containing residual solid particles, d) passing a portion of the second gaseous stream to a heat exchanger(s) to remove heat and e) recycling a portion of the cooled stream from (d) as the fluidizing gas in (a). The fouling rate of the heat exchanger (s) is such that i) the increase in pressure drop across the heat exchanger is equivalent to less than 5%/year, and/or ii) the decrease in heat transfer of the heat exchanger is equivalent to less than 5%/year.

Abstract: A hydrogen generator and a fuel cell system including the hydrogen generator are disclosed. The hydrogen generator includes a fuel composition including a hydrogen containing material that releases hydrogen gas to produce hydrogen when heated. A biasing member working in cooperation with a heating element and retainer, all of which are disposed within a unitary container, facilitate and control the release of hydrogen gas. The fuel composition can be segregated into individual quantities.

Abstract: A process for making a low density polymer in a polymerization reactor system, the process comprising polymerizing an olefin monomer, and optionally an olefin comonomer, in the presence of a diluent in a polymerization reactor to make a polymerization product slurry consisting of a liquid phase and a solid phase, wherein the solid phase comprises an olefin polymer having a density of between about 0.905 g/cm3 to about 0.945 g/cm3; and discharging the polymerization product slurry from the polymerization reactor through a continuous take-off valve to make a mixture further comprising a vapor phase. The mixture comprises a pressure less than a bubble point pressure of a component in the polymerization product slurry.

Abstract: The invention concerns a purge/sampling system for vessels, particularly for high temperature, high pressure vessels such as hydroconversion reactors used in refinery processes and operated in severe conditions. Such purge/sampling system comprises a purge/sampling line (16) equipped with a connector designed to be connected to the vessel (10), a first (18 and a second (20) flow regulation systems mounted in series on the purge/sampling line, wherein at least one injection line (22) is connected to the purge/sampling line between the first and the second flow regulation systems, said injection line comprising connecting means to a source of cleaning fluid (24) and at least one flow regulation device to control the flow of cleaning fluid through injection line and purge/sampling line The invention also concerns a vessel equipped with such a purge/sampling system, as well as a cleaning method using said purge/sampling system.

Abstract: An improved process for synthesizing acrylic polymers, which is highly controllable to achieve high molecular weight, high conversion rate, and low polydispersity involves continuously introducing initiator(s), acrylic monomer(s), and optionally other monomers capable of polymerizing with the acrylic monomer(s), into a microchannel of a microreactor having an integral micromixer and an integral heat exchanger.

Abstract: Methods are provided for producing a molecular array comprising a plurality of molecules immoblized to a solid substrate at a density which allows individual immobilized molecules to be individually resolved, wherein each individual molecule in the array is spatially addressable and the identity of each molecule is known or determined prior to immobilization. The use of spatially addressable low density molecular arrays in single molecule detection and analysis techniques is also provided. Novel assays and methods are also provided.

Abstract: A powder is disclosed including core/shell particles having an average particle size of less than 1000 microns, each particle contains a liquid core that is substantially free of water and includes A) a polar liquid having a percent surface polarity of at least 24%, an active ingredient, and C) from about 0.1% to about 20% by weight of at least one solubility enhancing agent that is not an active ingredient; and a shell comprising hydrophobic particles. The powder can be used to topically administer the active ingredient to a human or animal.

Abstract: Processes and systems for the production for pressure management of a polymerization product flowing from a loop polymerization reactor to a separation vessel in a slurry polymerization system are disclosed herein. For example, a process comprises withdrawing a polymerization product slurry from a loop polymerization reactor, conveying the polymerization product slurry through a first line comprising a continuous take-off valve to yield a mixture comprising a vapor phase, wherein the mixture exits the continuous take-off valve, and conveying the mixture through a second line comprising a flashline heater so that the mixture has a Froude number in a range from about 5 to about 100.

Abstract: A process for polymerizing olefins at temperatures of from 30° C. to 140° C. and pressures of from 1.0 MPa to 10 MPa in the presence of a polymerization catalyst in a multistage polymerization of olefins in at least two serially connected gas-phase polymerization reactors, and apparatus for the multistage polymerization of olefins, comprising at least two serially connected gas-phase polymerization reactors and a device for transferring polyolefin particles from an up-stream gas-phase polymerization reactor to a downstream gas-phase polymerization reactor, the transferring device comprising—a gas/solid separation chamber placed downstream of the upstream gas-phase polymerization which gas/solid separation chamber is equipped at a lower part with an net for introducing a fluid, and—connected to the gas/solid separation chamber at least two lock hoppers, placed in a parallel arrangement, each connected to the downstream gas-phase polymerization reactor.

Abstract: Embodiments of the present application provide a method for manufacturing a polyolefin and a system for implementing the method. The method comprises combining a catalyst with a diluent mixture containing a diluent and an olefin monomer in a polymerization reactor. The diluent may comprise propane, butane, or isobutane, or a combination thereof. The polymerization reactor is operated at a pressure above a critical pressure of the diluent, but below the critical temperature of the diluent.

Abstract: A method for forming a self-regenerating seal in a mixing chamber of a high-pressure mixing apparatus for polymeric components suitable for providing a reactive mixture for a polymerizable resin. An annular sealing element is provided in a circular housing seat inside the mixing chamber, in a sealing zone downstream the injection holes for the polymeric components; worn and/or torn parts of the annular sealing element are automatically regenerated by the same reactive mixture delivered during operation of the mixing apparatus. A high-pressure mixing apparatus with self-regenerating sealing element is also claimed.

Abstract: The invention relates to a catalyst metering device with a valve formed of an iron-based alloy steel hardened to a Rockwell hardness C of at least 60. The device can be used for metering of a catalyst for an ethylene polymerization reaction. The invention further relates to ethylene polymerization wherein the catalyst is metered in a catalyst metering device with a iron-based alloy steel hardened valve, as well as to a ethylene polymerization reactor comprising such a catalyst metering device.

Abstract: Embodiments described herein relate to in vitro cell culture. Embodiments include a substrate having a support layer that includes support molecules having a first region configured to bind to the substrate and having a photo-responsive region configured to change conformation between at least two conformations. In a first conformation of the photo-responsive region, the support molecules are configured to be more accessible to cells. In a second conformation of the photo-responsive region, the support molecules are configured to be less accessible to cells.