Abstract: A grafting reagent and related method of using the reagent to form a polymeric layer on a support surface, and particularly a porous support surface, in a manner that provides and/or preserves desired properties (such as porosity) of the surface. The reagent and method can be used to provide a thin, conformable, uniform, uncrosslinked coating having desired properties onto the surface of a preformed, and particularly a porous, polymeric substrate.

Abstract: An exhaust smoke denitrating apparatus in which using an NH3 injection unit, compressed air is fed from blower to ejector for extracting of exhaust gas from HRSG1, and with thus obtained mixed gas, NH3-containing gas is produced from NH3 water by NH3 water evaporator, the NH3-containing gas injected through NH3-containing gas injection nozzle of the HRSG1 disposed on a front stream side of denitration catalyst layer. As any high-temperature exhaust gas is cooled and diluted by compressed air, there is no danger of oxidation of NH3 during the stage of evaporation of NH3 water. The moisture level of exhaust gas can be lowered, thereby enabling inhibition of any drain generation in exhaust gas extraction piping. Air warming within NH3 water evaporation system can be carried out at an early stage.

Abstract: A method for sterilizing a plastic bottle in an aseptic filling system according to which at least an inner surface or an outer surface of a bottle is sterilized by injecting a heated sterilizing fluid at 65° C.-90° C. while maintaining internal pressure of the bottle at 1 kPa-20 kPa.

Abstract: Disclosed are compositions and methods for the biocompatible sterilization of materials, in particular, of medical devices and implants. Sterilization is achieved by deactivation of microorganisms through treatment of the material with a mixture of at least one microbiocidal additive and a high-pressure or supercritical fluid, for example, high-pressure carbon dioxide or supercritical carbon dioxide. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A method of sterilizing an article includes placing the article into a chamber containing an inner atmosphere and exhausting the inner atmosphere to lower pressure in the chamber. Hydrogen peroxide vapor is present in the chamber during at least a portion of the step of exhausting the inner atmosphere. Exhaustion of the inner atmosphere is terminated and additional hydrogen peroxide is admitted into the chamber. Hydrogen peroxide vapor contacts the article for a sufficient period to effect sterilization of the article.

Abstract: Hydrogen peroxide is vaporized (20) and mixed (30) with ammonia gas in a ratio between 1:1 and 1:0.0001. The peroxide and ammonia vapor mixture are conveyed to a treatment area (10) to neutralize V-type, H-type, or G-type chemical agents, pathogens, biotoxins, spores, prions, and the like. The ammonia provides the primary deactivating agent for G-type agents with the peroxide acting as an accelerator. The peroxide acts as the primary agent for deactivating V-type and H-type agents, pathogens, biotoxins, spores, and prions. The ammonia acts as an accelerator in at least some of these peroxide deactivation reactions.

Abstract: A jacket of a steam sterilizer embedding a sterilization chamber (3) consisting of two separated and independent each other parts of which a heating part (1) of the jacket embeds the sterilization chamber (3) while a filling part (2) of the jacket is advantageously arranged in the bottom part of the sterilization chamber (3), said parts form the integral unit. Both the outlet of a first steam filling valve (4) and the inlet of a first pressure sensor (5) enter the heating part (1), and both the outlet of a steam filling valve (6) and the inlet of a second pressure sensor (7) and the inlet of a third steam filling valve (8) enter the sterilizing chamber (3) into which both the outlet of the third steam filling valve (8) and the inlet of a third pressure sensor (9) enter, enter the area of the filling part (2).

Abstract: A sterilizer for medical instruments is compact and designed to be placed on a table top. The sterilizer provides includes a cavity for receiving a cassette holding the instruments to be sterilized. A stream circuit provides steam to the cassette for sterilization, and the time required for sterilization is reduced by withdrawing air from the cassette by application of a vacuum. The cavity is evacuated at the same time as the cassette to prevent application of high stresses to the cassette during the vacuum-assisted withdrawal of air. The time for sterilization is further reduced by use of dual heat exchangers to reduce the volume removed from the cassette.

Abstract: A chemical vapor sterilization process is enhanced by concentrating a germicide via exploitation of the difference between the vapor pressures of the germicide and its solvent. A diffusion restriction can be placed into the diffusion path to assist this process and the path then opened to provide rapid diffusion of the thus concentrated germicide. The path through the diffusion restriction can be closed to allow the pressure in a sterilization chamber to be lowered prior to receiving the concentrated germicide.

Abstract: The apparatus and method for sterilising caps/stoppers for pharmaceutical purposes comprises a vessel, pump, heater, circulation line. The sterilising liquid (hot water, steam) is heated and pumped to the vessel where a fluidised bed of caps etc. is generated. After leaving the vessel the liquid is circulated/heated. Optionally an additive (siliconisation in case rubber parts) or cooling liquid is added. Further, the vessel is disconnectably attached to the supply lines for transportation to a production facility.

Abstract: An integrated duct system is utilized to admit an antimicrobial vapor into a vehicle to decontaminate the contents and surfaces of the vehicle and subsequently to remove the vapor. The ducts comprise an air conditioning and/or heating duct, a decontamination duct for admitting an antimicrobial vapor, an auxiliary circulation duct for diffusing the vapor throughout the vehicle, and an aeration duct for removing the vapor from the vehicle, as well as a catalytic converter for detoxifying the antimicrobial vapor before removal. The integrated decontamination system is suitable for the chemical or biological decontamination of vehicles, provides enhanced vapor delivery and distribution on a rapid basis and also provides for rapid aeration for removing the antimicrobial vapor.

Abstract: A sterilization system that includes a sensor for determining the concentration of a liquid sterilant in a sterilant fluid. The sterilant fluid is comprised of a blend of sterilant fluids from a plurality of sterilant supplies. The concentration of the liquid sterilant differs in each of the sterilant supplies. The sensor allows a controllable concentration of liquid sterilant to be supplied to a vaporizer.

Abstract: A method for increasing a relative humidity in an enclosed space (10) comprising a plurality of graduated steps. The relative humidity is increased from a first relative humidity to a target relative humidity. The method is issued to humidify a chamber (10) wherein a sterilization process using a humidified ozone takes place. The method is carried out by an apparatus for effecting the humidified ozone sterilization comprising a processor programmed to effect humidification in a plurality of gradual steps.

Abstract: A method is disclosed that produces allografts from matrices typically containing demineralized bone matrix (DBM) powder, demineralized bone matrix gel, demineralized bone matrix paste, bone cement, cancellous bone, or cortical bone and mixtures thereof. The matrices are sterilized utilizing supercritical CO2 in the presence of a sterilizing additive and an entrainer such as an alkaline earth metal compound, preferably CaCO3. The resultant allograft materials have a reduced rate of rejection when used in allograft procedures including, bone, cartilage, tendon, and ligament grafting procedures.

Abstract: Apparatus (10), systems and methods are disclosed for treating a biological fluid with light. A container (206) of biological fluid is introduced into a fluid treatment chamber (40) where it is contacted with light provided by one or more light sources (60, 70) in proximity to the fluid treatment chamber (40). A light sensing system (650) senses the intensity of illumination of the light. A radiometer (460) may be inserted into fluid treatment chamber (40) to calibrate the light sensing system (650). An electronic control system (600) utilizes an interface circuit board (606) to interface a computer circuit board (602) to a display panel (37), a user interface panel (39, 39a), a relay circuit board (640), light sensors 404 and various other sensors (649). A detector (385) senses agitating movement of a tray (90) that contains biological fluids.

Abstract: A device for sterilization in production of packages (8) is adapted for sterilization with a gaseous sterilizing agent which is kept in the gaseous phase throughout the sterilization process. The device comprises a heating zone (2), a sterilization zone (3) and a venting zone (4). It further comprises means for maintaining a higher pressure in the sterilization zone (3) than in the heating zone (2) and venting zone (4). A method of sterilizing packages (8) in production of the packages (8) is also disclosed. The packages (8) have an open end (11) and a closed end (12) A gaseous sterilizing agent is used and kept in the gaseous phase throughout the sterilization process. A positive pressure is maintained in a sterilization zone (3) in which the sterilization is performed.

Abstract: The present invention provides a method and apparatus for sterilizing articles using an ozone-containing gas, where condensation of water from the sterilization atmosphere during the sterilization process is substantially prevented. The inventive sterilization method includes providing a sterilization chamber and placing an article into the sterilization chamber. The sterilization chamber is sealed prior to equalizing the temperature of the article and the atmosphere in the sterilization chamber. A vacuum is applied to achieve a preselected vacuum pressure in the sterilization chamber. Once the vacuum pressure is set, water vapour is supplied to the sterilization chamber. Ozone-containing gas is then supplied to the sterilization chamber and the sterilization chamber remains sealed for a preselected treatment period, where the sterilization chamber remains sealed throughout the whole process. Finally, vacuum in the sterilization chamber is released.

Abstract: The invention relates to an improvement in a method for sterilizing an article in a sterilizing chamber by exposing the article to humidified ozone in at least two consecutive sterilizing cycles, the improvement comprising, after the first of said consecutive sterilizing cycles and before the second of said consecutive sterilizing cycles, removing from the sterilizing chamber any condensed water present.

Abstract: A sterilizer includes a vacuum chamber, a source of vaporizable sterilant, a vacuum pump, and a control system. The control system is programmed to take one or more data inputs regarding the nature of the load, such as lumen length and diameter, and determine one or more parameters of the sterilization cycle based upon the inputs.

Abstract: A method for cleaning and sterilizing a medical device comprises the steps of: placing the device into a container; cleaning the device in the container with a cleaning solution; rinsing the device in the container with a rinse solution; and vaporizing a liquid substance in the container to create a sterilant vapor and contacting the device with the vapor to effect sterilization of the device.

Abstract: Phosphine gas is generated by agitating a reaction mixture of a metal phosphide and water with agitation air in a reaction pot of a phosphine gas generator. The resulting phosphine gas is then diluted with dilution air to produce a fumigant phosphine gas which is directly delivered to a commodity for fumigation. The reaction pot does not have any rotating means such as agitators, rotors, or stirrers. The generator provides on-site generation of phosphine gas in a rapid manner improving the fumigation efficiency for a commodity, such as grain, preferably contained within a storage structures, such as a grain silo. The generator has a built in deactivation system for the unused metal phosphide and phosphine gas.

Abstract: An apparatus for decontamination of objects, such as temperature-sensitive devices for military applications, comprises a vacuum chamber having an internal space for receiving an object to be decontaminated. A vacuum pump produces a vacuum in the internal space. A heater is used for heating the internal space. A first arrangement is provided for ventilation of the internal space, and a second arrangement is provided for filling the internal space with a gaseous chemical decontamination agent. The apparatus can be used optionally for disinfection or detoxification, with a low decontamination temperature being sufficient in both cases because of the low pressure in the chamber.

Abstract: The invention relates to a method for forming a molded article during sterilization and under high pressure utilizing a supercritical fluid as a sterilization fluid, whereby the pressurization and depressurization rates are controlled to form molded articles.

Abstract: A method is provided for maintaining the disinfection of medical equipment, in particular medical endoscopes (10), following processing. The method comprises placing the disinfected equipment (10) in a sealed chamber (12), and subsequently reducing the pressure within the sealed chamber (12) to cause evaporation of residual moisture. Gas scavenger sachets (21) are also provided within the sealed chamber (12) to remove atmospheric oxygen, thus causing a further reduction in the chamber pressure. The method may optionally include a further step of charging the sealed chamber (12) with a disinfectant gas or vapour. The processed medical equipment (10) is then maintained at the desired level of disinfection within the controlled biostatic environment in the sealed chamber (12).

Abstract: Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.

Abstract: A method for sterilizing at least one item in a chamber, comprising the steps of: disposing the at least one item in the chamber; pumping the atmosphere from the chamber until the atmosphere of the chamber has a pressure of less than ten torr; adding water vapor and ozone to the chamber; and generating electrical discharge in the chamber, such that the electrical discharge produces OH radicals from the water vapor and the ozone so as to contribute to sterilization of at least part of the at least one item.

Abstract: A sterilization method for drugs to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores is effective by subjecting the drugs to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions and controlling the pressurization and depressurization rates.

Abstract: A method and device for sterilizing containers in which a plasma treatment is executed through excitation of an electromagnetic oscillation so that the plasma is excited in a vacuum in the vicinity of the container regions to be sterilized. Between arrival and discharge, the container regions to be sterilized are moved closer to the oscillation-generating device in the chamber, with continuous movement of the container and/or of the oscillation-generating device for one or more predetermined time intervals in such a way that a plasma is excited in these regions inside and/or outside the container. The chamber is provided with a transport apparatus inside it, which produces an essentially rotating motion of the container during the transport from the arrival to the discharge in the chamber.

Abstract: A composition and process for the disinfection of the surface 0f an article which contains 1-(2-ethylhexyl)-glycerol ether for the disinfection of the surface of an article at a temperature above 25° C.

Abstract: A method and an apparatus for sterilizing a lumen device. A lumen and a container having an interface on a wall of the container are enclosed in a chamber. The lumen is placed across the interface so that one end of the lumen is in the container and the other end is in the chamber. Germicide is introduced into the chamber, and a pressure difference is created between the two ends of the lumen, so that the germicide flows through the lumen. The lumen may alternatively be placed across an interface which separates the chamber into two areas. Germicide is introduced into the chamber, and a pressure difference is created between the two areas of the chamber, causing the germicide to flow through the lumen.

Abstract: A sterilizer includes a vacuum chamber, a source of vaporizable sterilant, a vacuum pump, and a control system. The control system is programmed to take one or more data inputs regarding the nature of the load, such as lumen length and diameter, and determine one or more parameters of the sterilization cycle based upon the inputs.

Abstract: A system and method of disinfecting and sanitizing potable water on an aircraft. An ozone generator generates a supply of ozone which is fed into an injector. A pump is connected to a water supply line and an end of an injector. Water flows from the water supply line through the pump and into the injector where the water and the supply of ozone mix to disinfect the water.

Abstract: The present invention is directed to a method and apparatus for treating goods, such as, for example, fumigating and re-cooling perishable goods, such as fruit, using a tarp and floor seal. The apparatus encloses goods on a surface and includes a canopy that is substantially impermeable to flowable materials, such as gas, liquid, or a combination thereof; an upper perimeter for supporting an upper portion of the canopy; a lower perimeter for supporting a lower portion of the canopy, the lower perimeter to be placed in proximity to the surface; a support structure for supporting the upper perimeter and lower perimeters; and a gasket in communication with the lower perimeter, wherein the gasket is deformable to substantially seal the chamber by compressing the gasket against the surface. The apparatus may also include an intermediate support structure for providing support to the canopy and a conduit in communication with the chamber to supply cool air to the chamber.

Abstract: Disclosed herein is a system for sanitizing objects, particularly food products such as fruits and vegetables. The system includes two or more tanks for generation and storage of chlorine dioxide. The system provides for the simultaneous use and generation of chlorine dioxide so that the system avoids undesired down-time.

Abstract: A method and apparatus for metering a predetermined quantity of liquid decontaminant into a vaporization system. A single vacuum source is used to fill an injector with the predetermined quantity of liquid decontaminant and to also establish a vacuum in a chamber. The chamber is injected with the liquid decontaminant filling the injector. The liquid decontaminant is vaporized in the chamber to produce a vaporized decontaminant.

Abstract: A nebulant suitable for sterilization comprising finely divided liquid droplets suspended in a gas, said droplets including a solute, which is advantageously hydrogen peroxide and a solvent, for example water, wherein the droplets have a concentration of greater than 60 wt % of solute and an average diameter of less than 1.0 micron, preferably less than 0.8 microns.

Abstract: A multiflow gassing system for providing controlled environment gas to a lid and container, the system including a lid carrier; and a gas rail assembly adjacent the lid carrier, the gas rail assembly having a top portion including a top portion gas outlet, an end portion including a end portion gas outlet, and a plate adjacent the end portion. The top portion gas outlet is oriented to direct the controlled environment gas into the lid and the end portion gas outlet is oriented to direct the controlled environment gas into a lid-container engagement region.

Abstract: A process for cleaning donor soft tissue by removing contaminants by extraction using a fluid at supercritical temperature and pressures while preserving the integrity of the tissue.

Abstract: An apparatus for decontamination of objects, such as temperature-sensitive devices for military applications, comprises a vacuum chamber having an internal space for receiving an object to be decontaminated. A vacuum pump produces a vacuum in the internal space. A heater is used for heating the internal space. A first arrangement is provided for ventilation of the internal space, and a second arrangement is provided for filling the internal space with a gaseous chemical decontamination agent. The apparatus can be used optionally for disinfection or detoxification, with a low decontamination temperature being sufficient in both cases because of the low pressure in the chamber.

Abstract: A method for sterilizing objects (19), in particular medical or surgical instruments, includes subjecting a gas stream circulating in a chamber wherein an industrial vacuum is created to the action of an electric field so as to create a gaseous plasma whereof the post-discharge stream which is derived therefrom is admitted into a sterilizing chamber where it is contacted with the surface of the objects to be treated. The device is characterized in that the gas stream consists of a mixture of nitrogen, and of an amount of hydrogen less than 5%. It includes elements for heating the objects capable of bringing the latter, during treatment, to a temperature not less than 60° C.

Abstract: An improved method of altering a fluid-borne contaminant includes the steps of: providing a positive-displacement pump (21) having an inlet (22) and an outlet (23); connecting the pump inlet to a source (24) of contaminated fluid; operating the pump at a pressure ratio sufficient to elevate the pressure and temperature of the fluid and contaminants passing through the pump to alter or convert substantially all of the contaminants passing through the pump.

Abstract: A process to transform solid waste into fuel by adding water and heat to provide no more than 350 BTUs/lb of the weight of the solid waste for no more thatn 85 minutes. Such a process transforms the solid waste into fuel in a process time of not greater than 85 minutes. The system uses a pressure vessel; a condenser tank to permit selective addition of water to and evacuation of steam from the vessel; a heater to increase the temperature of the vessel; a vacuum pump to selectively reduce pressure within the vessel and to help evacuate steam from the vessel to the condenser tank; and a water pump to selectively add water from the condenser tank to the interior volume of the vessel. A method for converting solid waste into fuel includes loading the solid waste into a rotating pressure vessel and transforming the solid waste into fuel by adding water; reducing pressure; adding heat; and then evacuating steam. The contents are evacuated from the pressure vessel. At least some of the contents are fuel.

Abstract: A chlorine gas generating candle in a vented container which serves as a portable means to generate heated chlorine gas for killing insects, bacteria, viruses and other dangerous biological agents. The device has application in sanitizing dwellings, swimming pools and the like, and is effective in case of accidental release and/or biological attack. The chlorine gas generating candle disinfects an enclosed space with a quantity of heated chlorine gas. The chlorine gas generator is a self contained unit including an igniter which can be activated to initiate a self propagating burn of the entire candle and a resultant distribution of toxic chlorine gas. The use of one or a plurality of chlorine generators described in this application can provide any desired concentration of the killing gas. The chlorine gas generating candle can be safely and easily transported and does not require a source of power to operate.

Abstract: Described is a process and an arrangement for the treatment of objects, in particular for sterilization, comprising at least one chamber for the joint take-up of at least two objects to be treated. A closing element is arranged to the opening of the chamber, which closing element is arranged in a moveable way in the arrangement for the purposes of opening and closing the opening. The chamber can be closed by means of the closing element in a vacuum-tight way, whereby no relative movement takes place between the closing element and the chamber in the closed state. It is provided that the minimum of two objects to be treated are inserted one after the other, and that the closing of the opening by means of the minimum one closing element takes place essentially on a continuous basis.

Abstract: A method and an apparatus for sterilizing a lumen device. A lumen and a container having an interface on a wall of the container are enclosed in a chamber. The lumen is placed across the interface so that one end of the lumen is in the container and the other end is in the chamber. Germicide is introduced into the chamber, and a pressure difference is created between the two ends of the lumen, so that the germicide flows through the lumen. The lumen may alternatively be placed across an interface which separates the chamber into two areas. Germicide is introduced into the chamber, and a pressure difference is created between the two areas of the chamber, causing the germicide to flow through the lumen.

Abstract: A method and an apparatus for sterilizing a lumen device. A lumen and a container having an interface on a wall of the container are enclosed in a chamber. The lumen is placed across the interface so that one end of the lumen is in the container and the other end is in the chamber. Germicide is introduced into the chamber, and a pressure difference is created between the two ends of the lumen, so that the germicide flows through the lumen. The lumen may alternatively be placed across an interface which separates the chamber into two areas. Germicide is introduced into the chamber, and a pressure difference is created between the two areas of the chamber, causing the germicide to flow through the lumen.

Abstract: A method is provided for inactivating prions and is particularly effective in inactivating prions on medical devices. An article having a quantity of prions thereon is placed into a sterilization chamber. Pressure in the sterilization chamber is lowered to a pressure below the vapor pressure of hydrogen peroxide and a solution of hydrogen peroxide is admitted into the sterilization chamber and placed into contact with the article to inactivate prions on the article.

Abstract: A method is provided for inactivating prions and is particularly effective in inactivating prions on medical devices. An article having a quantity of prions thereon is placed into a sterilization chamber. Pressure in the sterilization chamber is lowered to a pressure below the vapor pressure of hydrogen peroxide and a solution of hydrogen peroxide is admitted into the sterilization chamber and placed into contact with the article to inactivate prions on the article.

Abstract: A sterilization container holds instruments during a sterilization process. It has en enclosure with an opening into the enclosure. A self-closing mechanism at the opening keeps the opening closed when not attached to a sterilant delivery source.

Abstract: A chemical vapor sterilization process is enhanced by concentrating a germicide via condensation and re-vaporization thereof, exploiting the difference between the vapor pressures of the germicide and its solvent to extract some of the solvent during the condensation process. A heat pump coupled with the condensation surface enhances the speed and efficiency of condensing and revaporizing the germicide.