Including Connector Patents (Class 422/538)
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Patent number: 12000765Abstract: A method and system for processing a sample in a fluid is provided. An assembly comprising a cap prefilled with a fixative solution, a valve, and a container for storing a tissue sample are provided. The valve is adapted to be situated between the cap and the container such that fluid can flow from the cap into the container when the assembly is upright, but the fluid cannot backflow from the container to the cap when the assembly is horizontal or inverted.Type: GrantFiled: March 9, 2021Date of Patent: June 4, 2024Assignee: Ventana Medic Systems, Inc.Inventors: Nathan Crum, Michael Otter
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Patent number: 12000763Abstract: A disposable blood sampler for a blood braid of a blood bag includes a blood taking needle cannula, a threaded cannula, a blood braid clamp, a connecting pipe, a needle inserting sheet and a blood braid. The blood taking needle cannula includes a tubular threaded structure at both ends, a bottom port of the threaded cannula is connected with the blood taking needle cannula, and an upper port of the threaded cannula includes symmetrically distributed clamping slots extending to a middle lower part of the wall. Grips are arranged on the outer wall surface of the blood braid clamp, and the blood braid clamp is arranged in the threaded cannula. The grip is arranged outside the clamping slot, and the connecting pipe is directly inserted into the upper port. An inner cavity in which the needle inserting sheet is placed is arranged inside the inner part of the connecting pipe.Type: GrantFiled: March 6, 2019Date of Patent: June 4, 2024Assignee: TAIZHOU PEOPLE'S HOSPITALInventors: Lingbao Gao, Yayun Sha, Ziang Gao
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Patent number: 9546395Abstract: Systems and methods for monitoring biofilm growth are provided. A method comprises supporting at least one coupon in a water reservoir, wherein the water reservoir feeds water into a tower interior, removing the at least one coupon from the water reservoir, and measuring a level of biofilm growth on the at least one coupon. The level of biofilm growth on the at least one coupon is predictive of a level of biofilm growth within the tower interior. Providing an indicator of predictive biofilm growth may allow measures to be taken to prevent biofilm growth in other sectors or areas of the tower.Type: GrantFiled: December 16, 2014Date of Patent: January 17, 2017Assignees: ROHM AND HAAS COMPANY, DOW GLOBAL TECHNOLOGIES LLCInventors: Peter Jasko, III, Robert Marquard, Christine Mcinnis
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Patent number: 9011801Abstract: The invention provides for fluidic connections to be established between tubes, ports, fluidic components and fluidic devices. The leak-tight connections are formed through controlled, compressive forces and can be used for both low and high pressure applications.Type: GrantFiled: June 6, 2012Date of Patent: April 21, 2015Assignee: Corsolutions LLCInventors: Thomas N. Corso, Colleen K. Van Pelt
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Patent number: 8840852Abstract: The invention relates to a sampling valve, for taking samples of fluid from a common collecting vessel in order to perform a plurality of analyses using reagents. The valve of the invention comprises two members that are movable relative to each other, comprising a sampling member having sampling loops, each intended to receiving an aliquot of fluid, and a connection member capable of assuming at least three functional positions relative to the sampling member. These three positions enable the delayed access to two separate sampling circuits in order to fill them and to dispense reagents to the loops that make them up.Type: GrantFiled: December 2, 2008Date of Patent: September 23, 2014Assignee: Horiba ABX SASInventor: Olivier Bouchentouf
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Patent number: 8821814Abstract: A microfluidic device including a platform and a cartridge is disclosed. The platform includes a chamber containing a fluid. The reagent cartridge is mounted to the platform. and contains a solid reagent for detecting material contained in the fluid.Type: GrantFiled: June 30, 2009Date of Patent: September 2, 2014Assignee: Samsung Electronics Co., Ltd.Inventors: Yoonkyoung Cho, Dogyoon Kim, Beomseok Lee, Jongmyeon Park, Hyunmin Kim, Yangui Lee, Jong Gun Lee
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Publication number: 20140206097Abstract: An apparatus for providing a sample gas includes a gas dosing part, a first pressure gauge for measuring a pressure of a sample gas dosed through the gas dosing part, a plurality of flow lines positioned between the gas dosing part and a gas analyzer that can be opened or closed according to the pressure measured by the first pressure gauge, a plurality of control valves respectively formed in the plurality of flow lines and controlling the plurality of flow lines to be opened or closed, a bypass line formed on at least one of the plurality of flow lines and exhausting some of the sample gas flowing along the flow lines, and a controller for selecting one of the plurality of flow lines according to the pressure measured by the first pressure gauge and controlling the control valves formed in the selected flow line.Type: ApplicationFiled: January 6, 2014Publication date: July 24, 2014Applicant: Samsung Electronics Co., Ltd.Inventors: Jong-Cheol Jeong, Kyung-Hwan Jeong, Jong-Soo Kim, Pil-Kwon Jun
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Patent number: 8758708Abstract: It comprises, in addition to a sampling system (3), at the outlet of a vat (1) containing the liquid to be sampled, a selector (4) that establishes switching on an array of similar vats (1), and especially a suction unit (5) that operates by releasing compressed air into a nozzle (28); the airflow direction is controlled by a valve (29) between a direction directed toward the outlet (6), causing the suction of the liquid from the vat (1), and an opposite direction when the valve (29) is closed, feeding the liquid back into the vat (1) and cleaning the pipe (2).Type: GrantFiled: September 24, 2010Date of Patent: June 24, 2014Assignee: Commissariat a l'Energie Atomique et aux Enegies AlternativesInventors: Christophe Brenneis, Hervé Lagrave, Jacques Mamert
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Patent number: 8758687Abstract: The present invention is an apparatus and fluid delivery system for automated assays. The apparatus, for example, may be used for western blotting that uses flow lines for multiple reagents. In one embodiment, the present invention comprises a tray base with one or more fixed or disposable trays for testing samples, multiple flow lines, and multiple valves and the system is used for automatic controlled delivery of different fluids from supply vessels to different trays and discharges them to designated reservoirs or sewage system with minimum of operator actions. The system may include air line to assist supply and discharge the fluids and also coupled with measuring vessels with adjustable volume and valves adapted to interface with a valve operating unit with drive means.Type: GrantFiled: May 6, 2011Date of Patent: June 24, 2014Assignee: Precision BiosystemsInventors: Gregory Gorelik, Rus Yukhananov
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Patent number: 8647591Abstract: A microarray reaction device includes a fluid container, a reaction chamber, a first channel connected with the fluid container, a second channel connected with the reaction chamber, and a valve. The valve includes a first and second support unit, respectively including a first and second penetration opening unit, extended through a first and second surface thereof. The first and second penetration opening unit is connected to a second end of the first and second channel, respectively. The second support unit includes a third penetration opening unit extended through a second surface thereof. The first and second surfaces contact each other, such that the first support unit and the second support unit are slidably disposed with each other. The microarray reaction device further includes a storing chamber connected with the third penetration opening unit, and a pump connected to the storing chamber and providing pressure to the storing chamber.Type: GrantFiled: January 17, 2011Date of Patent: February 11, 2014Assignee: Samsung Electronics Co., Ltd.Inventors: Won-seok Chung, Myo-yong Lee, Kak Namkoong, Woochang Lee
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Patent number: 8636964Abstract: An end-face sealing fluidic connector for fluidic connection and/or interconnection of glass, glass-ceramic and/or ceramic fluidic modules in a microreactor includes a connector body having a circular first end face with a recess for retaining one or more O-rings and a first end section having a circular cylindrical outeT surface and a diameter In the range of from 3 to 25 mm. The outer surface has a circumferential recess dividing the first end section into a proximal portion adjacent the first end face and a distal portion. A retaining ring is seated in the circumferential recess and a protecting ring coinpming a high-compression-strength polymer surrounds the proximal portion of the first end section. A circular cylindrical sleeve surrounds the first end section and the reinforcing and/or protecting ring, the sleeve including a circumferentially extending inside bearing surface for engaging the retaining ring on the distal side thereof.Type: GrantFiled: April 12, 2011Date of Patent: January 28, 2014Assignee: Corning IncorporatedInventors: Pierre Brunello, Paul Louis Florent Delautre, Sylvain Maxime F Gremetz, Olivier Lobet
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Patent number: 8585985Abstract: An apparatus for staining sample sections, comprising: a chamber that is adapted for fastening sample sections therein; and a pump that is adapted for pumping liquids through the chamber. The chamber has an inlet and an outlet. The inlet can be connected to at least one reservoir of a staining liquid via inlet lines that are controllable by valves. The inlet lines are formed at least in the region of the associated valves by means of elastic hose lines, and the valves are formed as hose pinch valves. This apparatus minimizes or eliminates contaminations arising from staining processes for thin sections that are in particular prepared for examination in an electron microscope.Type: GrantFiled: July 21, 2008Date of Patent: November 19, 2013Assignee: Leica Mikrosysteme GmbHInventors: Reinhard Lihl, Heinz Plank, Siegfried Tanki
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Publication number: 20130142709Abstract: The present disclosure relates to a calibration cartridge for an in vitro medical diagnostic device. The device also includes a removable assay cartridge containing a polymer body with channels for fluid movement.Type: ApplicationFiled: December 6, 2012Publication date: June 6, 2013Applicant: Edan DiagnosticsInventor: Edan Diagnostics
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Patent number: 8425863Abstract: A micro fluidic device includes a valve/pump-unit with reduced dead volume having a substrate. The lower surface of the substrate includes two micro channels spaced apart by a valve area of the substrate that separates the two micro channels. A flexible membrane is arranged on the lower surface of the substrate facing an actuating element located in a through going cut-out of a cover element. Movement of the actuating element towards and away from the valve area of the substrate causes a pump and/or valve action of the flexible membrane area, respectively, to cause or stop a directed fluid flow between the two micro channels through a channel formed between the valve area of the substrate and the flexible membrane.Type: GrantFiled: December 12, 2007Date of Patent: April 23, 2013Assignee: Koninklijke Philips Electronics N.V.Inventors: Chris Van Haag, Ronald Cornelis De Gier, Adrianus Wilhelmus Dionisius Maria Van Den Brijgaart, Gheorghe Sorin Stan
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Patent number: 8398938Abstract: A microfluidic thermal bend actuated pressure pulse valve having an inlet for receiving a flow of liquid, an outlet for outputting the flow of liquid, a meniscus anchor between the inlet and the outlet such that the flow from the inlet towards the outlet stops at the meniscus anchor where the liquid forms a meniscus, a movable member for contacting the liquid, and, a thermal expansion actuator for displacing the movable member to generate a pulse in the liquid to dislodge the meniscus such that the liquid flow towards the outlet resumes.Type: GrantFiled: June 1, 2011Date of Patent: March 19, 2013Assignee: Geneasys Pty LtdInventors: Mehdi Azimi, Matthew Taylor Worsman, Kia Silverbrook
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Patent number: 8372357Abstract: A rotatable microfluidic device that comprises a hydrophilic microchannel structure in which there is a) an upstream microcavity I with a liquid outlet I, b) a microconduit I connected to liquid outlet I, and c) a capillary valve I associated with microconduit I. The inlet end of the microconduit is closer to the spin axis than the outlet end of the microconduit. The difference in radial distance between the inlet end and the outlet end of microconduit I is typically ?5%, such as ?10% or ?100% or ?500%, of the difference in radial distance between the uppermost part of the upstream microcavity and liquid outlet I.Type: GrantFiled: April 13, 2006Date of Patent: February 12, 2013Assignee: Gyros Patent ABInventors: Per Andersson, Gunnar Ekstrand, Gérald Jesson
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Patent number: 8354074Abstract: A test module for biochemical processing and analysis, the test module having an outer casing dimensioned for hand-held portability, the outer casing having a receptacle for receiving biochemical liquid, and, a reagent reservoir containing a reagent for addition to the biochemical liquid for use in chemical analysis of the biochemical liquid, wherein, the reagent reservoir has a volume less than 1000,000,000 cubic microns.Type: GrantFiled: June 1, 2011Date of Patent: January 15, 2013Assignee: Geneasys Pty LtdInventors: Kia Silverbrook, Mehdi Azimi
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Patent number: 8268252Abstract: A unique combination of male and female gas connectors for one way transfer of gasses.Type: GrantFiled: April 26, 2011Date of Patent: September 18, 2012Assignee: GENO LLCInventors: Jody Fuller, David H. Fine
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Patent number: 8147773Abstract: A fluid dispenser useful in automated biological reaction systems comprising a barrel having a reservoir chamber, the barrel having an upper portion and a lower portion, a cap located on top of the upper portion of the barrel and connected to the reservoir chamber, the cap having an external surface with at least one hole therethrough, a valve comprising a biasing member and a hole sealer, the valve being located in the hole in the cap at the point where a downward force is applied against the cap, a coupler having a dispense chamber, the coupler being coaxial with the barrel and wherein the barrel lower portion moves into the dispense chamber during dispensing of fluid, and a vent located between the cap and the reservoir chamber, the vent including a vent opening and a vent material composed of oliophobic material.Type: GrantFiled: March 17, 2011Date of Patent: April 3, 2012Assignee: Ventana Medical Systems, Inc.Inventors: Charles D. Lemme, Vincent R. Rizzo, Jr., Bobbi Druyor-Sanchez, Anthony Ford, Bronwen Heilman, Darin McDaniel, Brian McGraw, Stephen Mead, William Richards, Wayne Showalter
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Publication number: 20120053088Abstract: A test module for biochemical processing and analysis, the test module having an outer casing dimensioned for hand-held portability, the outer casing having a receptacle for receiving biochemical liquid, and, a reagent reservoir containing a reagent for addition to the biochemical liquid for use in chemical analysis of the biochemical liquid, wherein, the reagent reservoir has an outlet with a surface tension valve for retaining the reagent in the reservoir with a reagent meniscus until contact with the biochemical liquid removes the reagent meniscus.Type: ApplicationFiled: June 1, 2011Publication date: March 1, 2012Inventors: Mehdi Azimi, Kia Silverbrook
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Patent number: 8124024Abstract: A cassette for preparing a sample is disclosed herein. The cassette includes a housing, which encloses the structures and the processes used to prepare the sample.Type: GrantFiled: May 28, 2010Date of Patent: February 28, 2012Assignee: GenturaDx, Inc.Inventors: Jesus Ching, David Hsiang Hu, Steve Jia Chang Yu, Phillip You Fai Lee
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Patent number: 8071057Abstract: A microfluidic valve device includes a microfluidic chip including a substrate having a channel, a valve disposed within the channel and configured to change a conductance of the channel, with the valve having an inner channel formed therein, and an oscillator configured to generate a traveling wave. The valve is moved by generating the traveling wave to open and close the channel.Type: GrantFiled: November 11, 2008Date of Patent: December 6, 2011Assignee: Canon Kabushiki KaishaInventors: Toshinobu Tokita, Kosuke Fujimoto
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Publication number: 20110281373Abstract: The invention relates to a sampling valve, for taking samples of fluid from a common collecting vessel in order to perform a plurality of analyses using reagents. The valve of the invention comprises two members that are movable relative to each other, comprising a sampling member having sampling loops, each intended to receiving an aliquot of fluid, and a connection member capable of assuming at least three functional positions relative to the sampling member. These three positions enable the delayed access to two separate sampling circuits in order to fill them and to dispense reagents to the loops that make them up.Type: ApplicationFiled: December 2, 2008Publication date: November 17, 2011Inventor: Olivier Bouchentouf
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Patent number: 8057758Abstract: Sample processing devices with variable valve structures and methods of using the same are disclosed. The valve structures allow for removal of selected portions of the sample material located within the process chamber. Removal of the selected portions is achieved by forming an opening in a valve septum at a desired location. The valve septums may be large enough to allow for adjustment of the location of the opening based on the characteristics of the sample material in the process chamber. If the sample processing device is rotated after the opening is formed, the selected portion of the material located closer to the axis of rotation exits the process chamber through the opening. The remainder of the sample material cannot exit through the opening because it is located farther from the axis of rotation than the opening.Type: GrantFiled: March 8, 2010Date of Patent: November 15, 2011Assignee: 3M Innovative Properties CompanyInventors: William Bedingham, Barry W. Robole, Ranjani V. Parthasarathy, Katya Ericson
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Patent number: 8017092Abstract: An analyzer enabling the user to hardly breathe in a malodor given off from a reagent when exchanging a reagent container is obtained. This analyzer, connected with a reagent container including a flexible container body storing the reagent, comprises an analyzer body analyzing an analyte with the reagent and reagent transporter having a first end connected to the analyzer body and a second end connected to the reagent container. The reagent transporter includes a first connectional part, detachably connected to the reagent container, having a first switching member forming and blocking a first passage between the analyzer body and the reagent container, while the first switching member blocks the first passage when the first connectional part is separated from the reagent container, and forms the first passage when the first connectional part is connected to the reagent container.Type: GrantFiled: December 16, 2004Date of Patent: September 13, 2011Assignee: Sysmex CorporationInventor: Karl-Heinz Bindrim
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Patent number: 7998437Abstract: A microfluidic assembly (1;57) has at least one microfluidic flow path (17,27,29,35,38;82,85,95) and at least one inlet port (11,13,15;81,97,101) coupled to the flow path (17,27,29,35,38;82,85,95). The microfluidic assembly (1;57) has a first microfluidic device (7;63) that executes a microfluidic process and has a second microfluidic device (9;61). The microfluidic assembly (1;57) has an interface (5;65). The interface (5;65) couples the first microfluidic device (7;63) and the second microfluidic device (9;61).Type: GrantFiled: February 16, 2007Date of Patent: August 16, 2011Assignee: Agilent Technologies, Inc.Inventors: Manfred Berndt, Marcus Gassmann
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Patent number: 7981386Abstract: A mechanically-actuated microfluidic valve. The valve comprises an inlet port; an outlet port; a thermal bend actuator; and a valve closure member cooperating with the actuator. Actuation of the thermal bend actuator causes movement of the closure member, thereby regulating a flow of fluid from the inlet port to the outlet port.Type: GrantFiled: June 20, 2008Date of Patent: July 19, 2011Assignee: Silverbrook Research Pty LtdInventors: Gregory John McAvoy, Kia Silverbrook
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Patent number: 7892471Abstract: The invention described herein provides an embedded wireless device such as a RFID tag molded into separate housing formed of any thermoplastic material compatible to that of the plastic material as the device to which the housing is to be attached. Subsequently, the housed tag assembly can be thermally bonded onto the device through many means which are well known and accepted in the industry.Type: GrantFiled: November 15, 2007Date of Patent: February 22, 2011Assignee: Millipore CorporationInventors: Aaron Burke, Joseph William Muldoon