Holder Patents (Class 422/560)
  • Patent number: 10876936
    Abstract: A thermal system for controllably altering a temperature within a reaction chamber in a sample processing assembly is described. The reaction chamber is bounded by a substrate and cover member in the sample processing assembly. The thermal system includes at least one thermal generator for generating temperature changes, one or more transfer layers for transferring temperature changes between the thermal generator and the sample on the substrate and a fluid isolator for isolating the thermal generator from fluid dispensed into the reaction chamber.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: December 29, 2020
    Assignee: LEICA BIOSYSTEMS MELBOURNE PTY LTD
    Inventors: Peter Toogood, Kenneth Heng-Chong Ng, Anthony Favaloro, Stephen John Bagnato, Gregory William Boyes
  • Patent number: 10711234
    Abstract: A microfluidic platform for investigating cell-based interactions with a chip base is made of a suitable plastics material with the appropriate optical properties. The chip base has a plurality of ports in fluid communication with a microfluidic channel for containing a culture medium in which cells are held. A gas permeable laminate is bonded to a bottom surface of the chip base. Each port has an internal inlet, connecting the port with the microfluidic channel, and a trough for containing a small reservoir of culture medium fluid adjacent to the inlet. When in use, culture medium can be aspirated from the microfluidic channel via the trough rather than directly via the internal inlet.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: July 14, 2020
    Assignee: AIM BIOTECH PTE. LTD.
    Inventors: Andrea Pavesi, Sei Hien Lim, Swee Khuan Lim, Chee Mun Kuan
  • Patent number: 10646876
    Abstract: The present invention is directed to a cap for a biochip storage well. The cap comprises a resilient sealant layer capable, under the application of pressure, of forming a vapour-proof seal with a line contact interface formation extending around the perimeter of a biochip storage well. An assay assembly comprising the cap of the invention and a biochip storage is disclosed. Methods of sealing a biochip storage well using a cap of the invention are also disclosed.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: May 12, 2020
    Assignee: RANDOX LABORATORIES LTD.
    Inventors: Stuart Jackson, Ivan McConnell, John Lamont, Peter Fitzgerald, Marc Wharry
  • Patent number: 10625273
    Abstract: A centrifuge insert for sample receivers and to a carrier for a centrifuge insert for sample receivers with snap locking connection. The centrifuge insert according to the invention has substantial advantages over known centrifuge inserts. These advantages are not limited to the fact that the carrier is attachable and disengageable in a particularly easy and comfortable manner. It is also feasible to use various carriers for different sample receivers. Furthermore, the centrifuge insert according to the invention is configured particularly light and compact so that a loading of the rotor is significantly lower for identical centrifugation powers or so that significantly higher RCA values can be used.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: April 21, 2020
    Assignee: Eppendorf AG
    Inventors: Sandra David, Sylke Grune
  • Patent number: 10598626
    Abstract: The present disclosure relates to a sensor arrangement including a housing, connectable to a process container and including a guiding passageway formed therein, and a sensor body displaceable in the guiding passageway between a first position and a second position, wherein the sensor body has at least one end section, which can be moved out of the housing and which includes at least one sensor element serving for registering a measured variable of a measured medium, wherein the at least one sensor element is arranged in the first position of the sensor body within a chamber formed in the housing and, in the second position of the sensor body, outside of the housing, and wherein the at least one end section of the sensor body has a base and a peripheral surface, wherein the at least one sensor element forms a part of the peripheral surface.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: March 24, 2020
    Assignee: Endress + Conducta GmbH+Co. KG
    Inventors: Ingrid Wunderlich, Michael Hanko, Christian Fanselow
  • Patent number: 10576437
    Abstract: A process for preparing a reactor (1), said reactor defining an opening (13) for the passage of a device for dispensing solid particles (3) suitable for charging the reactor with solid particles, the process comprising:—providing a sensor support device (2) to which a sensor is attached, said sensor being intended for collecting information on the charging of the reactor,—attaching the sensor support to a component of the reactor (5) different from the device for dispensing solid particles.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: March 3, 2020
    Assignee: TOTAL RAFFINAGE FRANCE
    Inventors: Julien Mairesse, Bernard Cottard
  • Patent number: 10197993
    Abstract: A method for performing quality control on a diagnostic analyzer includes receiving control measurement values from each of a plurality of diagnostic analyzers. A quality control measurement value is received from a target diagnostic analyzer. The quality control measurement value is compared with statistical criteria associated with the plurality of quality control measurement values received from the plurality of diagnostic analyzers. A comparison result is communicated to a user interface associated with the target diagnostic analyzer.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: February 5, 2019
    Assignee: SYSMEX CORPORATION
    Inventor: Scott Lesher
  • Patent number: 10144010
    Abstract: In a manipulation container (1) for cryomicroscopy, having at least one holder (9) for a sample carrier mount (7) and at least one manipulation opening (2) for manipulating sample carriers or sample carrier mounts (7), the holder (9) for a sample carrier mount (7) is movable into a displacement path (11), passing completely through the manipulation container (1), of a displacement apparatus (3) for the sample carrier mount (7).
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: December 4, 2018
    Assignees: Leica Mikrosysteme GmbH, European Molecular Biology Laboratory
    Inventors: Reinhard Lihl, Leander Gaechter, John Briggs, Martin Schorb
  • Patent number: 9399220
    Abstract: The disclosure relates to a retainer (100) for sample carriers (P1-P4) of different shapes and sizes. The retainer includes a retaining plane (110) for receiving the sample carrier; at least three respectively movably mounted stop elements (120), each of the stop elements (120) having at least one stop surface (121) which is embodied to be adjusted, by movement of the stop element (120), against the sample carrier (P1-P4); at least three securing elements (125), a securing element (125) being associated with each of the at least three stop elements (120); each of the at least three securing elements (125) configured to secure the associated stop element (120) immovably on the retainer, and configured to be conveyable into a first position in which the associated stop element (120) is movable, and to be conveyable into a second position in which the associated stop element is secured immovably on the retainer.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: July 26, 2016
    Assignee: Leica Microsystems CMS GmbH
    Inventor: Martin Kubek
  • Patent number: 9079183
    Abstract: Magnetic microplate assemblies are disclosed for assaying of biological activated magnetic particles from a supernatant. The assemblies include a magnetic microplate holder and a microplate including a plurality of wells for retaining the magnetic particles. The microplate holder includes a plurality of magnets for attracting the magnetic particles to the wells and a plurality of detents for securing the microplate in the holder. The detents allow the microplate to be tightly retained in the holder when the assembly is turned over to discard supernatant and wash buffer applied to rinse supernatant from the magnetic particles.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 14, 2015
    Assignee: QIAGEN GAITHERSBURG, INC.
    Inventors: Fei Yin, Bandele Jeffrey-Coker
  • Patent number: 9034281
    Abstract: A device (1, 100) for separating a membrane (81, 91) to analyze from a support (83, 93), the membrane being mounted in a frame (82, 92), itself mounted on a support, having a body (10) comprising a longitudinal recess (11, 110, 120) for translational reception of the assembly constituted by the frame mounted on the support, the recess having a first end (12) and a second end (13) and longitudinal sides (14A, 14B, 111, 121) facing each other between said two ends, the device having bearing means (30, 112, 122) for a first member of the frame/support group between the first and the second end of the recess, which are adapted to serve as a bearing for the first member of the frame/support group once the assembly is disposed in the recess, each of the sides having a ramp (15A, 15B, 112, 122) adapted to engage a gripping member (84, 73) of the second member of the frame/support group when the assembly is translationally moved from the first to the second end, said ramps being adapted to separate the support from t
    Type: Grant
    Filed: February 2, 2011
    Date of Patent: May 19, 2015
    Assignee: EMD Millipore Corporation
    Inventors: Frederic Marc, Luc Felden, Gael Waiche, Jean-Jacques Richert
  • Patent number: 9028756
    Abstract: A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored in a specimen container (150) and sampling it in a first container (153), a step for optically measuring the specimen in the first container, a step for sampling the specimen in a second container (154) and preparing a specimen for measurement by mixing the specimen with a reagent in the second container, and a step for analyzing the specimen for measurement according to the results of the optical measurement of the specimen.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: May 12, 2015
    Assignee: Sysmex Corporation
    Inventors: Norimasa Yamamoto, Takashi Yamato, Naohiko Matsuo, Satoshi Iguchi
  • Patent number: 9028754
    Abstract: A rack robot lifts and transfers sample tube storage racks or plates with a refrigerated enclosure maintained, e.g., at ?20° C. The samples are normally held in ultra-low temperature, e.g., ?80° C., or cryogenic freezers. From time to time, the racks or plates need to be roved from the ultra-low temperature or cryogenic freezers for processing and the rack robot transfers the racks or plates to the various processing stations within the refrigerated enclosure, such as tube picking, barcode reading, or frost removal stations.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: May 12, 2015
    Assignee: Hamilton Storage Technologies, Inc.
    Inventors: Fabian Winter, Halvard Solberg, Julian Warhurst, Frank Hunt, Behrouz Zandi
  • Patent number: 9017998
    Abstract: The present invention provides an apparatus for culturing cells which may comprise two or more culture compartments and a pooling compartment, wherein each of said two or more culture compartments may be separated from the other culture compartments; each of said two or more culture compartments which may comprise a port for the addition or removal of medium; and the pooling compartment communicates with said two or more culture compartments. The present invention also relates to a stand for apparatus for culturing cells.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: April 28, 2015
    Assignee: Plasticell Ltd.
    Inventors: Marina Tarunina, Yen Choo, Mylvaganam Jeyakumar, Martin Arthur Town, Diana Hernandez-Jaramillo, Christopher James Johnson
  • Patent number: 9011793
    Abstract: The present invention relates to a blood glucose monitoring system, a strip accommodation device, a strip storage device, and an automated blood collection device, wherein the blood glucose monitoring system has the strip accommodation device formed integrally therewith, the strip accommodation device being configured to convert a rotary motion of a cover of an operating member into an upward linear motion and to eject one of a plurality of strips through an ejection hole, thereby easily storing the strips therein, preventing the contamination of the strips from the foreign matters like outside moisture, and accurately and easily measuring the concentration of the glucose in the blood.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: April 21, 2015
    Inventor: In Sang Choi
  • Patent number: 9010269
    Abstract: A counting device includes a shaft, a handle affixed to a first end of the shaft, and a locking unit mounted in the handle spaced from the shaft. A locking plate has an opening for accommodating the shaft. The locking plate has a plurality of recesses facing the locking unit for cooperating with the locking unit. A position indicating assembly is coupled to the shaft to move as the handle is rotated. The recesses are arranged in a circular pattern on the locking plate such that the locking unit engages each recess as the handle is rotated around the shaft. The recesses are configured to permit one-way rotation of the handle.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: April 21, 2015
    Assignee: Dana Products, Inc.
    Inventors: Harry Bala, Mark Bala
  • Patent number: 9005550
    Abstract: The disclosure provides a multi-layered cell culture vessel having a rectangular shape with a top a bottom sides and ends, where the sides are longer than the ends. The vessel has hand grips and ports at each end of the rectangular vessel. The ports allow fluid entering into the vessel to flow into the multiple cell culture layers through a manifold. The ports may be incorporated into the hand grips.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 14, 2015
    Assignee: Corning Incorporated
    Inventors: Thomas L. Carter, Gregory S. Jordan
  • Patent number: 8999272
    Abstract: The present invention relates to a holder for at least one capture device (30) for collecting microdissected specimens, having a holding element (2) in which the at least one capture device (30) is to be arranged, the holding element (2) being transferable into a working position in order to collect microdissected specimens, the holding element (2) being mounted by way of at least two levers (3a, 3b) in a frame (1) of the holder (40), and being vertically displaceable relative to said frame (1) by way of a displacement of the levers (3a, 3b).
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: April 7, 2015
    Assignee: Leica Microsystems CMS GmbH
    Inventor: Gerhard Pfeifer
  • Patent number: 8986611
    Abstract: A sample analysis apparatus configured to automatically press a start button upon installation of a sample tube is provided. The sample analysis apparatus includes: a body of the sample analysis apparatus; a door housing which may be provided in an opened state or a closed state, and configured to be coupled to the body of the sample analysis apparatus by a hinge; a tube accommodating unit included in the door housing and configured to accommodate the sample tube; a start button included in the body of the sample analysis apparatus and configured to start analysis of the sample; and an operating member positioned at a first position which is distant from the start button the sample tube is not installed in the tube accommodating unit, and a second position which is configured to operate the start button when a sample tube is installed and the door housing is closed.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: March 24, 2015
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Yong Koo Lee, Tae Soo Kim, In Duk Hwang, Seock Woo Jang, Chul Ho Yun
  • Patent number: 8945486
    Abstract: A microwell device is provided. The device includes a plate having a upper surface. The upper surface has first and second recesses formed therein. Each recess has an outer periphery. First and second portions of microwells are formed in upper surface of the plate. The first portion of microwells are spaced about the outer periphery of the first recess and the second portion of microwells spaced about the outer periphery of the first recess. A first barrier is about a first portions of the microwells for fluidicly isolating the first portion of the microwells and a second barrier about a second portions of microwells for fluidicly isolating the second portion of the microwells.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: February 3, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jay W. Warrick, John Yin, Stephen M. Lindsay
  • Kit
    Patent number: 8940248
    Abstract: A kit comprising a carrier and vessels arranged on the carrier, wherein different reagents are contained in different vessels, the vessels are arranged with an openable closing device on top of the carrier, the carrier has a footprint on the bottom side for being placed on a base, and the carrier has bottom positioning means for being positioned on at least one workplace of an automated laboratory system for microtiter plates according to the SBS standard.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: January 27, 2015
    Assignee: Eppendorf AG
    Inventors: Judith Lucke, Jens-Peter Kroog, Helmut Knofe
  • Patent number: 8940247
    Abstract: A portable analyzer A1 includes: hole forming means designed to form a hole 3 for insertion of a specimen sampling implement 6 therein; and analyzing means capable of analyzing a specimen when the sampling implement 6 is inserted into the hole 3, the hole forming means including a first member 1 having a first region R1 corresponding to a portion of an internal surface of the hole 3, and a second member 2 having a second region R2 corresponding to another portion of the internal surface of the hole 3. The first and second members 1 and 2 are capable of relative movement while being coupled to each other, the relative movement causing at least one of the first and second regions R1 and R2 to be exposed to outside for easy cleaning thereof.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: January 27, 2015
    Assignee: ARKRAY, Inc.
    Inventors: Yoshiharu Uehata, Hiroyuki Nakanishi
  • Patent number: 8932543
    Abstract: An apparatus including a reagent cartridge and a reaction chamber, the reagent cartridge having a reagent capsule removably positioned therein for dispensing of a reagent onto the reaction chamber. A system including a linearly translatable mounting assembly having a plurality of mounting stations dimensioned to receive at least one fluid dispensing cartridge, a linearly translatable bulk reagent dispensing assembly having a plurality of bulk reagent dispensing nozzles coupled thereto and a receiving assembly positioned beneath the mounting assembly and the bulk reagent dispensing assembly, the receiving assembly including a plurality of reaction stations.
    Type: Grant
    Filed: September 21, 2011
    Date of Patent: January 13, 2015
    Assignee: Sakura Finetek U.S.A., Inc.
    Inventors: Xuan S. Bui, Anthony L. Hartman, Toshiyuki Fujimaki, Shinji Tokudaiji, Yoshitake Okabe, Yoshitada Mizusawa
  • Patent number: 8900514
    Abstract: The invention discloses a blood analyzing device (100) comprising a holder (110) arranged for carrying a container (10) having a cuvette (20) containing a blood sample (30). The container (10) is positioned in the holder (110) so that a longitudinal axis (60) of the cuvette (20) is angled relative a horizontal axis (70). A light source (120) provides light (40) into the sample (30) and a detector (130) detects the output light (50) from a sub-portion of the blood sample (30). Kinetic information indicative of the change in hemoglobin concentration in a measuring volume (32, 34) is determined by a Hb processor (145) from the detected output light (50). An ESR processor (140) determines the erythrocyte sedimentation rate of the sample (30) based on the kinetic information.
    Type: Grant
    Filed: September 1, 2008
    Date of Patent: December 2, 2014
    Inventor: Tommy Forsell
  • Patent number: 8900533
    Abstract: A blister package for a plurality of pipette tips comprises a support block with a plurality of molded pockets that extends into the support block from a first wall. The plurality of pockets is configured to receive the plurality of pipette tips. At least one reservoir located within the support block at a distal end of and in fluid communication with at least one of the plurality of pockets. A closure member configured to close the plurality of pockets within the support block.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: December 2, 2014
    Assignee: Molecular Bioproducts, Inc.
    Inventor: Jesse B. Cohen
  • Patent number: 8894951
    Abstract: A specimen collection container having a transitional fill-volume indicator is disclosed. The specimen collection container includes an open top end, a closed bottom end, and a sidewall extending therebetween defining an interior. The specimen collection container includes a transitional fill-volume indicator adjacent the sidewall, such that the container defines a first volumetric interior defined by the sidewall between the closed bottom end and the transitional indicator. The specimen collection container also defines a second volumetric interior defined by the sidewall between the closed bottom end and a portion of the sidewall disposed above the transitional indicator.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: November 25, 2014
    Assignee: Becton, Dickinson and Company
    Inventors: Bradley M. Wilkinson, Craig Owen Russ
  • Patent number: 8894950
    Abstract: Disclosed is a test cassette comprising a continuous length of test carrier tape (22) in a supply chamber (12), the supply chamber (12) having an opening (52) sized so as to allow the test carrier tape (22) to pass through into a test zone (32) into an uptake chamber (14) where the test carrier tape (22) coils itself onto an uptake mandrel (26), the supply chamber (12) being sealed from the environment whereby the opening (52) of the supply chamber (12) allowing the exit of the test carrier tape (22) has a spacer (42) disposed either side of it, filling the remaining width of the opening (52) of the housing (16), a cover plate (34) being biased by a spring (38) to cover the spacer (42) and tape (22), thus covering the opening (52) and sealing the cassette (10).
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: November 25, 2014
    Inventor: Brandon Bransgrove
  • Patent number: 8883075
    Abstract: An attractive and compact device and an effective method to store and disinfect a manual shaving razor are disclosed. The method reduces corrosion of the razor's metal blades. A compact container has separate but suitably connected chambers allowing for economy of use of as disinfectant liquid combining alcohol, detergent or soap and skin conditioner. By protecting the razor in one enclosed chamber, oxidative damage and rusting of blades is avoided. A knife edge element is placed at the bottom of another chamber to pierce the foil seal of a suitably inserted bottle within the other chamber. An optional third, drainage chamber below the other two chambers allows for appropriate drainage and removal both of excess fluid used, as well as hair and debris from the blades. The design of the device is compact and attractive, as is the method an extremely effective way of protecting and disinfecting the razor.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: November 11, 2014
    Inventors: Christopher J Henry, Robert F Patterson
  • Patent number: 8875361
    Abstract: A method of making a grid for a battery plate of a lead-acid battery. A substantially planar web is manufactured to include a plurality of spaced apart and interconnected wire segments, which at least partially define substantially planar surfaces, have a plurality of transverse lands, and interconnect at a plurality of nodes to define a plurality of open spaces between the wire segments. The web is reformed to change the cross-sectional shape of the wire segments. Other aspects may include simultaneously reducing the thickness of at least a portion of the web while reshaping the wire segments, and/or providing controlled surface roughness on at least one of the surfaces of the web to increase surface area of the grid and thereby promote adhesion of an electrochemically active material to the grid.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: November 4, 2014
    Assignee: Wirtz Manufacturing Co., Inc.
    Inventors: John W. Wirtz, John O. Wirtz, Jack E. McLane
  • Patent number: 8877144
    Abstract: An apparatus for processing a biological sample is provided, the biological sample being arranged on a first planar surface of a carrier. The apparatus comprises a second planar surface arranged substantially parallel to said first planar surface and at a first distance from said first planar surface, said first planar surface and said second planar surface being arranged at an angle (A) greater than zero degree from the horizontal plane (HP); and supply means for supplying an amount of a liquid that is to be applied to said biological sample. The first planar surface and said second planar surface are configured to be arranged at a second distance from each other, said second distance being such that said supplied amount of liquid is distributed over said biological sample when said first planar surface and said second planar surface are brought to said second distance from each other.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: November 4, 2014
    Assignee: Dako Denmark A/S
    Inventors: Tim Svenstrup Poulsen, Steen Hauge Matthiesen
  • Patent number: 8877146
    Abstract: A cassette for holding a tissue sample includes a body having a bottom wall and a plurality of side walls extending upwardly with respect to the bottom wall to define an interior space for receiving the tissue sample. A lid is configured to be received in the interior space, and the cassette is sectionable in a microtome. Sensing elements are associated with the body or lid and configured to allow an automated sensing system to determine at least one characteristic of the cassette. A flange extends along upper portions of at least two of the side walls and includes a plurality of holes. Other features are included to more effectively and efficiently manufacture and use the cassette.
    Type: Grant
    Filed: January 2, 2007
    Date of Patent: November 4, 2014
    Assignee: Biopath Automation, L.L.C.
    Inventors: Warren P. Williamson, IV, Thomas J. Ward, Stephen P. Whitlatch
  • Publication number: 20140322743
    Abstract: A microfilter comprising a polymer layer formed from epoxy-based photo-definable dry film, and a plurality of apertures each extending through the polymer layer. A microfilter comprising two or more polymer layers formed from epoxy-based photo-definable dry film, and a plurality of apertures or open areas each extending through the polymer layer. A method of forming a microfilter is also disclosed. The method includes providing a first layer of epoxy-based photo-definable dry film disposed on a substrate, exposing the first layer to energy through a mask to form a pattern, defined by the mask, in the first layer of dry film, forming, from the exposed first layer of dry film, a polymer layer having a plurality of apertures extending therethrough, the plurality of apertures having a distribution defined by the pattern, and removing the polymer layer from the substrate.
    Type: Application
    Filed: November 21, 2012
    Publication date: October 30, 2014
    Applicant: Creatv Microtech, Inc.
    Inventors: Cha-Mei Tang, Yunqi Zhang
  • Patent number: 8871161
    Abstract: The present invention relates to a reaction plate holding device and system associated therewith for controlling the environment surrounding a reaction plate, and in particular, to a bench-top reaction plate holder providing a controllable environment that fully surrounds a reaction plate.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: October 28, 2014
    Assignee: The National Institute for Biotechnology in the Negev Ltd.
    Inventors: Chen Haim Guttman, Raz Zarivach
  • Patent number: 8871156
    Abstract: An interface cartridge for a microfluidic chip, with microfluidic process channels and fluidic connection holes at opposed ends of the process channels, provides ancillary fluid structure, including fluid flow channels and input and/or waste wells, which mix and/or convey reaction fluids to the fluidic connection holes and into the process channels of the microfluidic chip.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: October 28, 2014
    Assignee: Canon U.S. Life Sciences, Inc.
    Inventors: Ray Tsao, Hiroshi Inoue, Shulin Zeng, Brian Murphy, Kenton C. Hasson
  • Publication number: 20140308181
    Abstract: A device for providing pipette tips includes a plate-shaped carrier with a base surface, holes in the carrier perpendicular to the base surface, at least one vertically running cut-out in the outer sides of two opposing narrow sides of the carrier to accommodate two vertical guide ribs at a distance from each other, pipette tips in the holes, a bottom part with sidewalls that extend upwards from a standing surface, said sidewalls surrounding a rectangular seat for the carrier with the inserted pipette tips, wherein two opposing first sidewalls project further upward from the standing surface than to opposing second sidewalls, a supporting mechanism on the inner sides of at least two opposing sidewalls to support the carrier in a horizontal alignment at the bottom edges of narrow sides, and two vertical guide ribs engaging in the at least one cut-out when the carrier is placed on the supporting mechanism.
    Type: Application
    Filed: April 11, 2014
    Publication date: October 16, 2014
    Applicant: EPPENDORF AG
    Inventor: Michael Blumentritt
  • Patent number: 8852535
    Abstract: A device and method for measuring the level of elemental sulfur present in a gas in a gas line. The device may include: an access fitting detachably connectable with the gas line, the access fitting having a first end and a second end; a probe detachably connectable to at least one end of the access fitting and adapted for insertion into a gas flow stream from the gas line to recover condensed components on the probe's outer surface; and a piping partially disposed within the probe for providing a cooling medium to the probe.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: October 7, 2014
    Assignee: Saudi Arabian Oil Company
    Inventors: Ihsan Al-Taie, Abdulaziz A. Al-Mathami, Helal M. Al-Mutairi
  • SK
    Publication number: 20140287517
    Abstract: This invention relates to methods and means for performing pool and other water and liquid testing. Some embodiments of the methods and means of the invention also incorporate additional functionality including, but not limited to communication, sensing, display and data processing elements. Various embodiments of the methods and means of the invention may be performed by and/or implemented in hardware, in software, by one or more entities, and/or by some combination of hardware, software and/or one or more entities.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 25, 2014
    Inventor: Alfred M. Haas
  • Patent number: 8815181
    Abstract: A delivery apparatus for selectively delivering one or more liquid reagents into a reaction or test chamber (2), especially of an assay apparatus, the apparatus comprising: one or more respective storage chambers (5,6) for containing the one or more liquid reagents and arranged generally above the reaction or test chamber (2); and a plunger element (4) arranged and operable for insertion into the mouth of a selected storage chamber so as to displace a selected reagent from therewithin into the reaction or test chamber (2) generally therebelow by gravitational liquid overflow from the mouth of the chamber. The apparatus may conveniently be provided as a discrete delivery unit, with the storage chambers (5,6) pretilled with the selected reagents.
    Type: Grant
    Filed: October 23, 2012
    Date of Patent: August 26, 2014
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventor: David James Squirrell
  • Patent number: 8815182
    Abstract: An apparatus for holding a contact lens during in vitro testing includes a first support member, a second support member, an alignment rod, and a cage member. The first support member includes a first end cap and a body portion. The body portion includes grooves formed in a lateral surface extending from the first end cap. The alignment rod is configured for interconnecting the body portion and a second end cap of the second support member. The cage member is positionable about the body portion between the first and second end caps, and includes an inner surface, an outer surface, and a plurality of openings between the inner surface and the outer surface. The inner surface and the lateral surface cooperatively define an annular space therebetween and a plurality of fluid flow paths between the inner space and the openings. The annular space is configured for receiving the contact lens.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: August 26, 2014
    Assignee: Agilent Technologies, Inc.
    Inventors: Deon Smit, Jeffrey Kuhn, Jeremy Fetvedt
  • Patent number: 8808646
    Abstract: A system collects data relating to a process performed within an autoclave, and wirelessly transmits the data to a receiver located outside the autoclave for processing. One or more sensors inside the autoclave sense process parameters such as temperature or pressure. The transmitter is housed in a protective container that protects the transmitter against the effects of autoclave heat and pressure.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: August 19, 2014
    Assignee: The Boeing Company
    Inventors: Karl M. Nelson, Anoshiravan Poursartip
  • Patent number: 8809069
    Abstract: A lab member for use in a laboratory liquid handling system including a pipetting module and a drive system, the pipetting module including first and second pipettors, the first and second pipettors including first and second pipettor shafts, respectively, a first pipetting tip extending from an end of the first pipettor shaft, and a second pipetting tip extending from an end of the second pipettor shaft, includes a lab object and first and second integral adapter structures. The first and second adapter structures are configured to engage the first and second pipettor shafts, respectively. The first adapter structure is configured to releasably secure the lab member to the first pipettor shaft.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: August 19, 2014
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Lee Brady, Larry Schoell, Gary Millard, Richard R. Harazin
  • Patent number: 8802037
    Abstract: A multiple cuvette strip comprises a plurality of wells and a reversible interlocking device. The well strips can be reversibly interlocked to other well strips to form a sample holder system. One embodiment of a well strip comprises a flange and a slot to form a reversible interlocking device.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: August 12, 2014
    Assignee: Instrumentation Laboratory Company
    Inventors: Matthew R. Blouin, Robert R. Fisette
  • Patent number: 8790599
    Abstract: A system for analyzing, manipulating, and recording data associated with a microtiter plate is provided. The system provides a touch screen element provided proximal to the microtiter plate such that data pertaining to events and conditions observed within one or more wells of the microtiter plate may be easily and accurately recorded. Data display, storage, and manipulation features are also provided.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: July 29, 2014
    Inventors: David Childs, Michael Sharer
  • Patent number: 8790600
    Abstract: The invention discloses a sample-support element for ultra-high vacuums comprising a main chamber and a supplementary chamber for the sample holder and the heating/cooling elements, which is pumped by a related pump line. This enables the reduction or total elimination of the negative effect related to the alteration of the residual atmosphere in ultra-high vacuums resulting from heating or cooling the surfaces of the sample holder.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: July 29, 2014
    Assignee: Fundacion Tekniker
    Inventors: Roman Nevshupa, Marcello Conte, Andoni Delgado Castillo, Camillus Petrus Domi Van Rijn
  • Patent number: 8784752
    Abstract: Methods and devices for adding liquids to and washing a microfluidic element array are disclosed. The method and devices feature a microfluidic plate holder with a sloped wall for improved draining of liquid, a machine readable/writable identifier, plate leveling systems, liquid filling systems, a hydrophilic-liquid coating, and an automated washing station.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: July 22, 2014
    Assignee: Curiox Biosystems Pte Ltd
    Inventors: Namyong Kim, Kong Leong Cheng, Li Li, Teow Soon Seah
  • Patent number: 8778285
    Abstract: The present invention relates to a clamping system comprising two or more grids of springs in a flow module or in a plate reactor. The invention also relates to methods for opening and closing a clamping system, a frame arrangement, a control system for pressure release, and a use of the clamping system as a plate reactor.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: July 15, 2014
    Assignee: Alfa Laval Corporate AB
    Inventors: Kasper Hoglund, Magnus Lingvall, Tommy Noren
  • Patent number: 8778283
    Abstract: A delivery apparatus for selectively delivering one or more liquid reagents into a reaction or test chamber (2), especially of an assay apparatus, the apparatus comprising: one or more respective storage chambers (5,6) for containing the one or more liquid reagents and arranged generally above the reaction or test chamber (2); and a plunger element (4) arranged and operable for insertion into the mouth of a selected storage chamber so as to displace a selected reagent from therewithin into the reaction or test chamber (2) generally therebelow by gravitational liquid overflow from the mouth of the chamber. The apparatus may conveniently be provided as a discrete delivery unit, with the storage chambers (5,6) prefilled with the selected reagents.
    Type: Grant
    Filed: January 25, 2010
    Date of Patent: July 15, 2014
    Assignee: The Secretary of State for Defence
    Inventor: David James Squirrell
  • Patent number: 8765077
    Abstract: Multiplex binding assay assemblies are disclosed. The assemblies generally include at least one assay bar that includes a top side, a bottom side, and at least one well accessible from the top side of the assay bar. Each well includes a side surface, a bottom surface, an open top end, and at least one secondary container, with each secondary container including a capillary tube that (i) begins at a location within an interior volume of the well and (ii) ends at a location beneath the bottom surface of the assay bar. The assemblies further include a dispenser bar that is adapted to be positioned adjacent to the top side of the assay bar, which includes one or more reservoirs that are configured to provide one or more reagents to the at least one secondary container located in each well of the assay bar.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: July 1, 2014
    Inventor: Pierre F. Indermuhle
  • Patent number: 8765476
    Abstract: Automated sample processing systems may include onboard efficient high-speed mixing of at least two components with an automatic vertical force fluidic turbulent component mixer of which a mixed component may be aspirated and high-speed dispensed in a mixing vial. Other aspects may include single sweep applying a multi-treatment cleaning cycle to at least one slide. A multi-treatment cleaning cycle may include a washing treatment and a drying treatment. In yet other aspects the present invention may include an automated recovery sample processing system with the capability of detecting at least one immediate condition of a fortuitously terminated automatic sample processing run and perhaps even an automatic terminated sample processing run reconstruction calculator.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: July 1, 2014
    Assignee: Biocare Medical, LLC
    Inventors: Saradha Avantsa, Ravishankar Melkote, Thomas Maxwell, Geoffrey Cook
  • Patent number: 8753583
    Abstract: An apparatus (10) for handling specimen slides (32, 78, 80) has at least one coverslipping module (14) for coverslipping thin sections arranged on specimen slides (32, 78, 80). The apparatus (10) further encompasses a drying unit (16, 70, 90) for extracting solvent from the mounting medium applied onto the specimen slides (32, 78, 80). The drying unit (16, 70, 90) has an air delivery unit (40) for delivering an air flow to the specimen slides (32, 78, 80).
    Type: Grant
    Filed: November 25, 2011
    Date of Patent: June 17, 2014
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Bernhard Neef, Simon Keimer, Karl-Heinz Westerhoff