Means Is Conveyor And Rack Patents (Class 422/65)
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Patent number: 8329103Abstract: An sample analyzer, which enables to confirm an analysis remaining time for each sample and a total analysis remaining time for all samples set in the analyzer, so that time management for both each sample and all samples can be easily performed, is disclosed. Specifically, an analyzing unit analyzes a sample by executing an analysis sequence including a predetermined number of analyzing steps, and an control device calculates an analysis remaining time for each sample based on the number of analyzing steps. Control device acquires a total analysis remaining time by calculating the analysis remaining time for the sample in which sample information is lastly inputted. The display member displays the analysis remaining time and the total analysis remaining time.Type: GrantFiled: September 18, 2008Date of Patent: December 11, 2012Assignee: Sysmex CorporationInventors: Yuji Wakamiya, Tomohiro Okuzaki, Hisato Takehara
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Patent number: 8329427Abstract: The invention relates to a method and device for the cross-referencing of identification (1) of tissue slice supports (2), for microtomised analytical samples still to be mounted thereon, with identification information (3) of a tissue sample holder (4) of a tissue sample (5) which is not yet microtomised. The conventional problem of cross-referencing is improved in a simple manner, whereby the identification information (3) for the tissue sample holder (4) is automatically detected when positioned in the microtome (6) and an identification (1) corresponding thereto is automatically transferred to at least one tissue slice support (2) and that tissue slice support (2), provided with the identification (1), is dispensed for application of the tissue sample slice at the moment when a tissue sample slice must be applied to a tissue slice support (2).Type: GrantFiled: May 9, 2008Date of Patent: December 11, 2012Assignee: Microm International GmbHInventors: Hans L. Heid, José Novoa
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Patent number: 8322510Abstract: There is described an automated laboratory system for handling test tubes containing biological material specimens supported by conveying devices (3) along guide lanes (1, 2), in which motorized conveyor belts (62) run, comprising main lanes (1) and secondary lanes (2) for overtaking the conveying devices (3) and/or routing the conveying devices (3) of the test tubes (4) to the various pre-testing, (19-20), testing (17) and post-testing stations (21).Type: GrantFiled: November 26, 2008Date of Patent: December 4, 2012Assignee: Inpeco IP Ltd.Inventor: Gianandrea Pedrazzini
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Patent number: 8318095Abstract: An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises a loading station (2) for microscope slides (7) with tissue specimens, a number of reagent stations (3) for staining of the tissue specimens on supplied microscope slides, a conveyor (5) for transfer of microscope slides (7) between the stations (3) in accordance with a staining program, an unloading station (10) for treated microscope slides, and a control unit (19) for controlling the treatment operations in accordance with a data program. The apparatus comprise a photo station (25) with a digital camera (26) for automatic photographing with a background light source of the finished treated tissue specimens on supplied microscope slides (7).Type: GrantFiled: January 31, 2007Date of Patent: November 27, 2012Assignee: Dako Instrumec ASInventors: Øystein Ljungmann, Torstein Ljungmann
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Publication number: 20120294764Abstract: A sample-processing system that improves total system processing efficiency, and reduces a sample-processing time, by establishing a functionally independent relationship between a rack conveyance block with rack supply, conveyance, and recovery functions, and a processing block with sample preprocessing, analysis, and other functions. A buffer unit with random accessibility to multiple racks standing by for processing is combined with each of multiple processing units to form a pair, and the system is constructed to load and unload racks into and from the buffer unit through the rack conveyance block so that one unprocessed rack is loaded into the buffer unit and then upon completion of process steps up to automatic retesting, unloaded from the buffer unit. Functional dependence between any processing unit and a conveyance unit is thus eliminated.Type: ApplicationFiled: July 27, 2012Publication date: November 22, 2012Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Hitoshi TOKIEDA, Yoshimitsu TAKAGI, Takeshi SHIBUYA, Masashi AKUTSU
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Publication number: 20120295358Abstract: Disclosed are magnetic conveyor systems and apparatus having a magnetic coupling with a housing and moveable magnet therein. The moveable magnet is substantially constrained in one dimension and adapted to move in another. The moveable magnet is adapted to magnetically couple with an attracting portion of a sample rack and move the rack along a conveying surface. Ease of transfer of sample racks is provided while minimizing spillage from the open sample containers therein. Method of operating the conveyor system are provided, as are other aspects.Type: ApplicationFiled: January 20, 2011Publication date: November 22, 2012Applicant: Siemens Healthcare Diagnostics Inc.Inventors: Gregory Ariff, Timothy Evers, Milind Sawant, Tumkur Vijay
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Publication number: 20120294765Abstract: There is provided an analysis apparatus in which congestion does not occur and whose analysis efficiency is high as a whole even when the apparatus is an automatic analyzing apparatus to which a plurality of functional modules having different functions and process performances from each other are connected. Also, there is provided an automatic analysis system in which, even when a new functional module is added, it is not required to consider influence on the existing functional modules and restructure a carrying plan or others for improving process performances as a whole. Buffer units paired with the respective functional modules are connected to a specimen carrying line, and an operating-section computer issues an instruction for carrying to the respective functional modules in accordance with requests for specimens, so that carrying-in/out operations are performed as managing respective carrying-possible states among the buffer units and functional modules.Type: ApplicationFiled: January 28, 2011Publication date: November 22, 2012Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Osamu Watabe, Masashi Akutsu, Hitoshi Tokieda
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Patent number: 8313694Abstract: An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another. Each treatment step occurs within the same reaction compartment. The reaction conditions of each reaction compartment for treating a slide can preferably be controlled independently, including the individualized application of reagents to each slide and the individualized treatment of each slide. The reagents are preferably held in a reagent dispensing strip similar to a “blister pack”.Type: GrantFiled: August 29, 2011Date of Patent: November 20, 2012Inventor: Lee Angros
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Patent number: 8313713Abstract: A device and method solves the problems of improving precision, in particular in reducing movement of a cuvette, particularly lateral or side to side movement of a cuvette, during the measurement process. The device, which stabilizes a cuvette during a measurement read in an analyzer having a cuvette path of travel, includes: a fixed support located on a first side of the path of travel and abutting a side of the cuvette at a location that does not interfere with an optical window on the cuvette on which the measurement read takes place; and a movable support located on a second side of the path of travel and biased against a side of the cuvette at a location that does not interfere with the optical window on the cuvette on which the measurement read takes place, and which is opposite the side abutting the fixed support.Type: GrantFiled: June 17, 2004Date of Patent: November 20, 2012Assignee: Ortho-Clinical Diagnostics, Inc.Inventors: Merrit N. Jacobs, Robert Anthony Burkovich, David Lee Johnson
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Patent number: 8309027Abstract: Provided is a specimen preparation apparatus capable of supplying a specimen from the specimen preparation apparatus to a specimen analyzer without burdening an operator. This specimen preparation apparatus comprises a stained specimen preparation part for preparing a specimen on a slide glass and staining the specimen, a keeping part for storing the stained specimen slide glass prepared in the stained specimen preparation part and a control part for deciding whether to supply the stained specimen slide glass to the keeping part or to the external apparatus.Type: GrantFiled: June 29, 2012Date of Patent: November 13, 2012Assignee: Sysmex CorporationInventors: Masanori Nakaya, Yoshihiro Hyousa, Shigeru Kitagawa, Eisuke Kobayashi, Hideyuki Higuchi
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Patent number: 8309026Abstract: A specimen preprocessing system includes a determination section for determining with respect to a height of a specimen container; a specimen container lifting mechanism for lifting an opening portion of the specimen container held in a specimen rack to a same predetermined level based on determination information data of the determination section; and a plug opening mechanism for opening a plug of the specimen container lifted to the same predetermined level by the specimen container lifting mechanism.Type: GrantFiled: July 28, 2008Date of Patent: November 13, 2012Assignee: Hitachi High-Technologies CorporationInventors: Naoto Tsujimura, Nobuo Suzuki, Katsushi Takahashi
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Patent number: 8303915Abstract: A platen for contacting a liquid to a surface of a substantially flat substrate is disclosed. The platen includes a liquid application station and a stripping element at an end of the liquid application station, wherein the stripping element includes an intersecting gap and an air barrier. Also disclosed are an apparatus including the platen and a method of using the platen to contact a substrate with a liquid.Type: GrantFiled: October 29, 2007Date of Patent: November 6, 2012Assignee: Ventana Medical Systems, Inc.Inventors: Brian H. Kram, Vincent R. Rizzo, Ryan Reeser, David Chafin
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Patent number: 8298815Abstract: Systems and methods of sample processing and temperature control are disclosed. The invention may especially relate to temperature control, and may in some embodiments be methods of temperature control of an automated sample processing system and methods of automated sample processing. Specifically, the present invention provides temperature control in relation to sample processing systems and methods of processing samples, and in some embodiments provides temperature control in relation to sample carriers and processing materials such as reagents. Corresponding systems and devices are disclosed, including sample processing systems (1), sample carrier temperature regulation systems (60), reagent temperature regulation systems, sample processing control systems, and temperature regulation devices, among other embodiments.Type: GrantFiled: December 22, 2003Date of Patent: October 30, 2012Assignee: DAKO Denmark A/SInventors: Kristopher Buchanan, Marc Key, John Favuzzi, Rosanne Welcher, Benno Guggenheimer, Robert Clark, Michael Barber, Bob Lathrop
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Patent number: 8298498Abstract: An apparatus and method of loading reagent in a specimen handling device is disclosed, where the apparatus includes a deck with a plurality of positions defined thereon and each of the positions visually marked by a distinct one of a first set of icons. Each of a plurality of trays is removably securable to a selected one of the positions on the deck and includes the distinct one of the first set of icons visually marking the selected one of the positions. Reagent receptacles on each of the plurality of trays are visually marked by a distinct one of a second set of icons, and a kit is provided with a plurality of containers with selected reagents therein, each of the containers being visually marked by the distinct one of the second set of icons visually marking the receptacle into which that reagent is to be poured. The fluids including specimen samples and reagents are moved between tubes during processing without directly passing over tubes which the reagents could contaminate.Type: GrantFiled: July 21, 2006Date of Patent: October 30, 2012Assignee: Abbott LaboratoriesInventors: Scott Safar, Stephen Herchenbach
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Patent number: 8298497Abstract: A delivery apparatus for selectively delivering one or more liquid reagents into a reaction or test chamber (2), especially of an assay apparatus, the apparatus comprising: one or more respective storage chambers (5,6) for containing the one or more liquid reagents and arranged generally above the reaction or test chamber (2); and a plunger element (4) arranged and operable for insertion into the mouth of a selected storage chamber so as to displace a selected reagent from therewithin into the reaction or test chamber (2) generally therebelow by gravitational liquid overflow from the mouth of the chamber. The apparatus may conveniently be provided as a discrete delivery unit, with the storage chambers (5,6) prefilled with the selected reagents.Type: GrantFiled: December 14, 2009Date of Patent: October 30, 2012Assignee: The Secretary of State for DefenceInventor: David James Squirrell
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Patent number: 8298484Abstract: The present invention relates to an analyzer (1) which includes a placement part (11) for placing an analysis piece, and a photometric measurer (7) for photometric measurement of the analysis piece (2). In the analyzer (1), the placement part (11) holds the analysis piece (2) in such a way that a row of reagent pad (20) on the analysis piece (1) lie in right-and-left directions (D3, D4). The photometric measurer (7) is farther from a front than the placement part (11). The analysis piece (2) placed on the placement part (11) is conveyed from front toward rear (Direction D1), with the row of reagent pads (20) laid in right-and-left directions (D3, D4), toward the photometric measurer (7).Type: GrantFiled: May 10, 2005Date of Patent: October 30, 2012Assignee: ARKRAY, Inc.Inventors: Yasumitsu Takagi, Hisakazu Sugie, Toshiyuki Otsuki, Norimasa Nishida, Yoshikiyo Hongo
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Publication number: 20120269680Abstract: A transportation mechanism for transporting a test tube rack laterally and intermittently is disclosed. The transportation mechanism includes a test tube rack, one or more fingers and a driving mechanism that drives the finger to move. The finger has a loading state and an unloading state in its movement process. In the loading state, the finger extends upward and into the test tube rack and causes the rack to move laterally. In the unloading state, the finger retrieves downward and out of the test tube rack. Because the finger is driven by the driving mechanism, there is no need to use a restriction metal sheet to press down the finger. As a result, there is no mechanical collision between the finger and the restriction metal sheet, and noise is effectively reduced in the operation.Type: ApplicationFiled: April 17, 2012Publication date: October 25, 2012Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Sheng CAO, Lechang LI
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Patent number: 8293175Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to receive said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge or from said pipette.Type: GrantFiled: November 13, 2009Date of Patent: October 23, 2012Assignee: Axis-Shield ASAInventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
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Patent number: 8288168Abstract: Improved systems and methods for tissue processing are described here. The chemical process and the construction of the apparatus are simplified by using only two different solutions in two separate reaction modules. They are compatible with processing of tissue specimens for genetic analysis, histology, in situ antibody binding and hybridization, archival preservation of morphology and nucleic acids, and combinations thereof.Type: GrantFiled: November 20, 2008Date of Patent: October 16, 2012Assignee: The University of MiamiInventor: Azorides R. Morales
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Patent number: 8277752Abstract: An optical measurement apparatus is provided for conducting a test by efficiently reading color development of a reagent after reaction by optical measurement. To the above end, an optical measurement apparatus is provided which is to be used with at least one test instrument mounted to the apparatus. The test instrument includes a carrier provided with at least one reagent retaining portion which retains a reagent, and a sample is applied to the carrier. The optical measurement apparatus includes a reader for reading color development of the reagent retaining portion, and a controller for performing driving control of the reader and determination. The controller performs the determination by utilizing data obtained by a reading operation P to read the color development of the reagent performed after the lapse of a reaction completion period Tr1-Tr6 from the mounting of the test instrument, and the reaction completion period depends on the reagent.Type: GrantFiled: November 20, 2008Date of Patent: October 2, 2012Assignee: ARKRAY, Inc.Inventors: Takashi Nakagawa, Shinya Nakajima, Tokuo Kasai, Kazuhiro Ohmiya
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Patent number: 8277729Abstract: The present invention is to present a sample analyzer which is capable of respond immediately when a need to perform analysis of multiple items arises. The sample analyzer 1 includes a table 12 capable of holding a first rack 320 and a second rack 330; a reagent dispensing arm 120 which comprises a pipette part 121; a reagent dispensing driving section 120a for moving the reagent dispensing arm 120; a reagent barcode reader 350; and a control section 501 for controlling the reagent dispensing driving section 120a so as to move the pipette part 121 to a predetermined reagent aspirating position according to the identification information obtained by the reagent barcode reader 350.Type: GrantFiled: March 27, 2008Date of Patent: October 2, 2012Assignee: Sysmex CorporationInventors: Naohiko Matsuo, Hiroyuki Fujino, Takamichi Naito, Nobuhiro Kitagawa
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Patent number: 8277730Abstract: A tissue infiltration apparatus (1) for specimens present in cassettes (5) comprises at least two liquid containers (7, 11, 13, 15) and a transport apparatus (6). Multiple cassettes (5) are receivable in a transport basket (4). The transport apparatus (6) is configured in such a way that at least two transport baskets (4) are transportable in the tissue infiltration apparatus (1). A transport basket (4) is deliverable to, and/or movable away from, a liquid container (7, 11, 13, 15) with the transport apparatus (6). An execution sequence (21) in which the transport baskets (4) pass through the liquid containers (7, 11, 13, 15) is definable. To enable accelerated or preferred processing of a transport basket (4) with the tissue infiltration apparatus (1), at least one means (8) is provided with which the order of two transport baskets (4) is definably modifiable.Type: GrantFiled: October 12, 2011Date of Patent: October 2, 2012Assignee: Leica Biosystems Nussloch GmbHInventors: Hermann Ulbrich, Karl-Heinz Westerhoff, Stefan Künkel, Janet Minshew
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Patent number: 8278114Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.Type: GrantFiled: March 2, 2010Date of Patent: October 2, 2012Assignee: Applied Biosystems, LLCInventors: Michael Gambini, Jeff Levi, John Voyta, John Atwood, Susan Atwood-Stone, legal representative, Bruce De Simas, Edward Lakatos, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 8268241Abstract: A process wherein outgassing rates of volatile organic compounds (VOCs) in an object, particularly habitable vehicles, are accelerated by placing the subject object in a vacuum chamber and placing heat sources either inside the object being treated, outside the object, or both. The process includes measuring and monitoring the temperature of selected surfaces inside the object being treated. The heat sources are adjusted to maintain a temperature which is safe for the materials and which will promote maximum outgassing rates. During the treatment process, while a vacuum and heat are being applied to the subject object, the gasses in the chamber are monitored for both their composition and quantity. When the outgassing rates of the VOCs reach acceptable levels, the process cycle is terminated. The vacuum in the chamber is broken to restore atmospheric pressure, and the object being treated is removed from the chamber.Type: GrantFiled: October 14, 2008Date of Patent: September 18, 2012Inventor: Henry W. Cooper
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Patent number: 8262994Abstract: An analyzer comprising: a first specimen holder configured to hold a plurality of first specimen containers; a conveying assembly for conveying the first specimen containers held in the first specimen holder; a second specimen holder arranged at a position higher than an upper end of the first specimen containers held in the first specimen holder; a holder moving assembly for moving the second specimen holder so as to pass the upper side of at least one of the first specimen containers held in the first specimen holder; a container transferring assembly for transferring at least one of the first specimen containers from the first specimen holder to the second specimen holder; and a controller for controlling the holder moving assembly and the container transferring assembly, is disclosed.Type: GrantFiled: December 13, 2011Date of Patent: September 11, 2012Assignee: Sysmex CorporationInventors: Yuichi Hamada, Masaharu Shibata, Daigo Fukuma
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Patent number: 8262991Abstract: The present invention relates generally to an apparatus for analysing fluid taken from a body, and more in particularly for analysing body fluids from mammals. The analysis apparatus is coupled to a dairy system for milking of cows, wherein it may be useful to analyse the status of the milk. The apparatus is preferably located as early as possible in the production chain in order to obtain results as close as possible to the cows. Hence the environment in which the apparatus is to be used may be harsh towards internal apparatus modules or consumables, therefore the apparatus is isolated and the internal environment is conditioned regarding humidity, temperature as well as the amount of ammonium. Furthermore the steps for analysing milk is automated inside the apparatus in order to avoid influence from the external environment.Type: GrantFiled: May 19, 2004Date of Patent: September 11, 2012Assignee: Lattec I/SInventors: Thomas Nikolai Carlsen, Peter Christiansen, Kristjan Freyr Gudmundsson, Frederik Nikolaj Svaerke Sonnenborg
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Patent number: 8257968Abstract: The present invention concerns an apparatus (1) for staining tissue samples, said apparatus (1) including a reagent section (2) or reagent containers (3); at least one staining section or tissue samples, a robotic head (22) or robotic element (20) that may move reagent to a predetermined tissue sample, said robotic element (20) being moveable above the reagent and the staining sections, a control element (85) that may manage a staining process, a 2-D optical sensor (86) to detect two-dimensional image data of a relevant property and that can feed the captured image data to the control element (86). By providing the robotic element (20) with a 2-D optical sensor (86), a common image processor may be provided having multiple functions. By using a 2-D optical image processing system, the control system of the apparatus may easily be adapted to read various types of data presentations, just as actual images for sections of the apparatus may be identified in order to assess the condition of the apparatus.Type: GrantFiled: December 19, 2003Date of Patent: September 4, 2012Assignee: DAKO Denmark A/SInventors: Doug Sweet, Marc Key, Gordon Feingold, Kristopher S. Buchanan, Bob Lathrop, John Favuzzi
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Patent number: 8252233Abstract: A sample-processing system that improves total system processing efficiency, and reduces a sample-processing time, by establishing a functionally independent relationship between a rack conveyance block with rack supply, conveyance, and recovery functions, and a processing block with sample preprocessing, analysis, and other functions. A buffer unit with random accessibility to multiple racks standing by for processing is combined with each of multiple processing units to form a pair, and the system is constructed to load and unload racks into and from the buffer unit through the rack conveyance block so that one unprocessed rack is loaded into the buffer unit and then upon completion of process steps up to automatic retesting, unloaded from the buffer unit. Functional dependence between any processing unit and a conveyance unit is thus eliminated.Type: GrantFiled: December 23, 2008Date of Patent: August 28, 2012Assignee: Hitachi High-Technologies CorporationInventors: Hitoshi Tokieda, Yoshimitsu Takagi, Takeshi Shibuya, Masashi Akutsu
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Patent number: 8252235Abstract: A liquid sample is aspirated using an aspirating tube provided with a flow path extending lengthwise in the interior of the tube, and an aspiration orifice for aspirating the liquid sample formed near the tip of the tube. The aspiration of the liquid sample to the aspirating tube is monitored during aspiration. Liquid sample is aspirated by the aspirating tube, and the collected material in the aspirating tube in the region at the tip side from the region containing the liquid sample to be used for measurement is delivered to a detecting part provided externally to the aspirating tube, and whether or not liquid sample is contained in the collected material is detected in the detecting part.Type: GrantFiled: August 28, 2006Date of Patent: August 28, 2012Assignee: Sysmex CorporationInventors: Masaharu Shibata, Yoichi Nakamura
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Patent number: 8252593Abstract: A sample analyzer is disclosed that includes a first measurement unit for measuring a sample, a second measurement unit for measuring a sample, and an information processing unit for acquiring a first analysis result based on a result of the measurement by the first measurement unit and a second analysis result based on a result of the measurement by the second measurement unit. The information processing unit is configured to correct the first analysis result based on a first correction value, correct the second analysis result based on a second correction value, update the first correction value, and update the second correction value. A calibration method of a sample analyzer is also disclosed.Type: GrantFiled: October 28, 2009Date of Patent: August 28, 2012Assignee: Sysmex CorporationInventors: Daigo Fukuma, Masaharu Shibata
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Patent number: 8252232Abstract: An automated storage system for storing large quantities of samples in trays includes a storage compartment, a tray shuttle compartment abutting the storage compartment on one side and a plurality of independent modules on the other side. The modules perform processing of samples that are retrieved from the storage compartment by a tray shuttle, including extraction of selected samples from retrieved source trays and transfer of the selected samples into a separate, destination tray that can be further processed or removed from the system for use. The independent operation of the modules permits handling and processing to be performed simultaneously by different modules while the tray shuttle accesses additional samples within the storage compartment. In one embodiment, a vertical carousel is used to vertically align a desired tray with the tray shuttle, while the tray shuttle operates within a horizontal plane.Type: GrantFiled: January 23, 2007Date of Patent: August 28, 2012Assignee: Brooks Automation, Inc.Inventors: Robert K. Neeper, Rhett L. Affleck, John E. Lillig
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Patent number: 8246908Abstract: By the conventional technique for dispensing more than one reagents accurately, the system is complicated and thus a compact and inexpensive system is difficult to realize. In the present invention, the pressurized dispensing system utilizing a capillary is realized, and in addition, in order to reduce the leakage of reagents different from the reagent dispensed, by forming air layers at the tips of the capillaries after dispensing, a compact, simple, inexpensive analysis apparatus is realized.Type: GrantFiled: February 21, 2007Date of Patent: August 21, 2012Assignee: Hitachi Ltd.Inventors: Tomoharu Kajiyama, Hideki Kambara, Kunio Harada
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Patent number: 8241568Abstract: A reaction tank for causing a reaction for analyzing a specimen in a humidity-applied atmosphere in a storage vessel, includes a humidifying unit that includes a water reservoir reserving water and a humidifier releasing moisture of the water reservoir to an inside of the storage vessel, the humidifying unit humidifying the inside of the storage vessel, and a humidity detector that detects humidity inside the storage vessel. An operation of the humidifier of the humidifying unit is turned ON when the humidity inside the storage vessel becomes lower than a predetermined suitable humidity whereas the operation of the humidifier of the humidifying unit is turned OFF when the humidity inside the storage vessel exceeds the predetermined suitable humidity.Type: GrantFiled: October 21, 2008Date of Patent: August 14, 2012Assignee: Beckman Coulter, Inc.Inventor: Tomohiko Takeuchi
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Patent number: 8241593Abstract: A holder for a plurality of biological specimen collection devices having collection absorbents extending therefrom is provided, the holder operating to organize and identify the collection devices and operating to position the collection devices for extraction of sample portions from each of the collection absorbents of the multiple collection devices while positioning a sample punch absorbent cleaning strip adjacent the collection absorbent of each device to allow cleaning of the sample punch between each use.Type: GrantFiled: February 7, 2007Date of Patent: August 14, 2012Assignee: The Bode Technology Group, Inc.Inventor: Jangbir S. Sangha
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Patent number: 8236255Abstract: An apparatus for treating slides has a base with a cavity, and a heater is located on a surface of the cavity. A tank, which supports a slide rack with the slides submerged in a slide treatment solution, is placed in the cavity with a tank surface immediately adjacent the heater. A temperature sensor is mounted in the base and is operable to provide a feedback signal representing a temperature of the liquid in the tank. A cover is removably hinged on the base to cover the tank. A control system is connected to the heater and the temperature sensor and has a user input/output that is operable to select a set temperature of the liquid and a cycle time.Type: GrantFiled: December 2, 2004Date of Patent: August 7, 2012Assignee: Lab Vision CorporationInventors: Glenn K. Takayama, Ken K. Tseung, Norman K. Rhett, Wai Bun Wong, Samuel Burd, George A. Harter, Douglas C. Morrison
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Patent number: 8232103Abstract: A method for replacing a first sample carried on a moving secondary conveyor onto a moving primary conveyor at a potential interference point while the primary conveyor is transporting a second sample.Type: GrantFiled: August 8, 2006Date of Patent: July 31, 2012Assignee: Siemens Healthcare Diagnostics Inc.Inventors: Kerry Lynn Miller, Frank Jay Robb, Peter Louis Gebrian, Sandor Lajos Kovacs
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Patent number: 8231830Abstract: A sample analyzer: measures a measurement sample including a sample and a reagent; creates a calibration curve based on first measurement data obtained by measuring a measurement standard sample including a standard sample and the reagent; provides calibration curve specifying information for specifying the calibration curve to the calibration curve; acquires an analysis result by processing second measurement data obtained by measuring the measurement sample based on the calibration curve; and stores the analysis result and the calibration curve specifying information provided to the calibration curve used in the process of the second measurement data in correspondence to each other.Type: GrantFiled: March 18, 2008Date of Patent: July 31, 2012Assignee: Sysmex CorporationInventors: Yuji Wakamiya, Tomohiro Okuzaki, Hisato Takehara
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Patent number: 8231829Abstract: A device for manipulating at least one specimen slide. The device includes a first sensor unit operable to sense a first rotation of a first component of the device about at least one first axis of a three-dimensional coordinate system. A second sensor unit is operable to sense a second rotation of a second component of the device about the at least one first axis of the coordinate system, the coordinate system being independent of a position of the first component and of a position of the second component. A positioning unit is operable to position the second component relative to the first component.Type: GrantFiled: September 15, 2009Date of Patent: July 31, 2012Assignee: Leica Biosystems Nussloch GmbHInventors: Simon Keimer, Juergen Tenhaef
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Patent number: 8231828Abstract: By the conventional technique for dispensing more than one reagents accurately, the system is complicated and thus a compact and inexpensive system is difficult to realize. In the present invention, the pressurized dispensing system utilizing a capillary is realized, and in addition, in order to reduce the leakage of reagents different from the reagent dispensed, by forming air layers at the tips of the capillaries after dispensing, a compact, simple, inexpensive analysis apparatus is realized.Type: GrantFiled: November 20, 2006Date of Patent: July 31, 2012Assignee: Hitachi, Ltd.Inventors: Tomoharu Kajiyama, Hideki Kambara, Kunio Harada
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Patent number: 8221683Abstract: Provided is a specimen preparation apparatus capable of supplying a specimen from the specimen preparation apparatus to a specimen analyzer without burdening an operator. This specimen preparation apparatus comprises a stained specimen preparation part for preparing a specimen on a slide glass and staining the specimen, a keeping part for storing the stained specimen slide glass prepared in the stained specimen preparation part and a control part for deciding whether to supply the stained specimen slide glass to the keeping part or to the external apparatus.Type: GrantFiled: March 22, 2010Date of Patent: July 17, 2012Assignee: Sysmex CorporationInventors: Masanori Nakaya, Yoshihiro Hyousa, Shigeru Kitagawa, Eisuke Kobayashi, Hideyuki Higuchi
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Patent number: 8221701Abstract: Provided is a microfluidic device that can automatically perform various types of biological blood analysis. In the microfluidic device, a specimen is centrifugally separated and the centrifugally separated specimen is diluted into various dilution ratios. Also, at least two reagents that are required for one reaction and that need to be separately stored are stored in separate chambers, and they are mixed when a reaction is needed. Thus, various conventional blood analyzing reagents can be used as they are or after being minimally processed in the microfluidic device.Type: GrantFiled: July 30, 2010Date of Patent: July 17, 2012Assignee: Samsung Electronics Co., Ltd.Inventors: Yoon-kyoung Cho, Do-gyoon Kim, Jung-nam Lee, Hee-kyun Lim
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Patent number: 8221702Abstract: A sample dispensing apparatus and method for dispensing a sample such as blood and urine collected for inspection from one vessel to another are provided wherein the remaining quantity of a primary sample can be reduced without disturbing the primary sample. When clogging by a separating agent is detected during suction of a sample such as blood and urine collected for inspection, the sample dispensing apparatus performs raising of an aliquot head such that an opening at the free end of a nozzle tip does not come out of the sample liquid surface to dissolve clogging; sucking of the sample under the residual pressure; and additionally sucking of a fixed quantity of the sample to reduce the remaining quantity of the sample.Type: GrantFiled: June 20, 2008Date of Patent: July 17, 2012Assignee: Hitachi-High Technologies CorporationInventors: Akihiro Shimoda, Masahito Kakuno, Eiji Takaya, Junichi Oizumi
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Patent number: 8221697Abstract: An automated lidder and/or delidder apparatus to engage and disengage a lid from a microplate is disclosed. The microplate includes a sample area with a plurality of individual wells and a hollow outer frame formed around the sample area, the frame being shaped to include a plurality of openings in its top surface. The lid includes a plate and a plurality of latches formed on the underside of the plate. In the lidding process, the apparatus presses down on the lid to insert each latch through a corresponding opening in the microplate until the latch snaps into engagement with the frame. In the delidding process, the apparatus inserts delidding posts into the openings to disengage the latches from the frame.Type: GrantFiled: August 2, 2010Date of Patent: July 17, 2012Inventors: Michael J. Nichols, Louis J. Guarracina
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Patent number: 8222048Abstract: A laboratory automation system that is capable of carrying out clinical chemistry assays, immunoassays, amplification of nucleic acid assays, and any combination of the foregoing, said laboratory automation system employing at least one of micro-well plates and deep multi-well plates as reaction vessels. The use of micro-well plates as reaction vessels enables the laboratory automation system to assume a variety of arrangements, i.e., the laboratory automation system can comprise a variety of functional modules that can be arranged in various ways. In order to effectively carry out immunoassays by means of micro-well plates, a technique known as inverse magnetic particle processing can be used to transfer the product(s) of immunoassays from one micro-well of a micro-well plate to another.Type: GrantFiled: October 24, 2008Date of Patent: July 17, 2012Assignee: Abbott LaboratoriesInventors: Patrick P. Fritchie, Gregory E. Gardner, Richard W. Mahoney
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Patent number: 8221684Abstract: A mobile intra-operative microscopic diagnosis laboratory capable of analyzing fresh tissue specimens and providing intra-operative consultation within 20 minutes is described. The mobile laboratory is preferably a van and contains a cryostat for freezing the fresh tissue specimens and a means for cutting the specimens. In addition, it also contains the means for reading the slides to make microscopic diagnosis and a means for handling for fresh tissue and a means for indicating various locations in the specimen, preferably by inking them. It preferably contains a stainer for staining the samples and an intercom for communicating the microscopic diagnosis back to the operating room.Type: GrantFiled: August 15, 2008Date of Patent: July 17, 2012Inventor: V. Raman Sukumar
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Publication number: 20120177535Abstract: A sample analyzer includes a transporting device configured to transport a rack for holding a plurality of sample containers containing samples respectively, a barcode reader configured to read a barcode of the rack transported by the transporting device, and an aspirating device that includes an aspirating tube and a moving device configured to move the aspirating tube in a direction to insert the aspirating tube in a sample container. The sample analyzer further includes a controller configured to determine, based on the container type identifying information included in the barcode read by the barcode reader, an aspiration position for aspirating a sample in a sample container and to control insertion of the aspirating tube in the sample container at the determined aspiration position, and an analyzing part configured to analyze the sample aspirated by the aspirating device.Type: ApplicationFiled: March 20, 2012Publication date: July 12, 2012Inventor: Kyozo FUJITA
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Publication number: 20120178170Abstract: An intelligent rack automatically detects the position of a specimen tube within a multiple specimen tube containing rack such as that utilized within automatic specimen processing apparatuses. The rack has a plurality of positions with a moving element located adjacent each position. The moving element, such as a spring, is positioned so that it moves when a specimen tube is placed within an adjacent position. A magnet or other sensor on the moving element interacts with a detector to sense when a particular position has received a specimen tube. A computer controlling the apparatus receives specimen information for each specimen tube and has an identifier for the specimen tube, such as a bar code, scanned into the computer before placement of the specimen tube into a rack position. Removal of the specimen tube from a position on the rack causes correlating removal of specimen tube position information from the computer.Type: ApplicationFiled: July 16, 2010Publication date: July 12, 2012Inventor: Peter Van Praet
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Patent number: 8216846Abstract: A method and a system for use of treatment liquids in an apparatus for staining of tissue specimens on microscope slides, wherein the apparatus comprises a plurality of vessels (4) for receiving different liquids for treatment of the tissue specimens, a plurality of tanks (11) for treatment liquids, connecting lines (15) between the tanks and the vessels, a plurality of pumps (13) connected on the connecting lines, and a control unit for control of the apparatus and the liquid treatment by means of a data program, wherein the control unit is arranged for selective control of the relevant pumps (13), so that vessels (4) to be used in a staining process, are filled with liquid (14) at the start of the staining process, and so that the liquid-filled vessels (4) are emptied automatically when they are no longer to be used in the staining process.Type: GrantFiled: December 22, 2005Date of Patent: July 10, 2012Assignee: Dako Instrumec ASInventors: Øystein Ljungmann, Torstein Ljungmann
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Patent number: 8216511Abstract: A specimen rack and a specimen carrier system includes a luminous body disposed on a vicinity of a specimen container loading slot to notify, to an operator, information concerning an analyzing situation and condition of the specimen contained in the specimen container held by the specimen rack.Type: GrantFiled: May 29, 2008Date of Patent: July 10, 2012Assignee: Hitachi High-Technologies CorporationInventors: Kiyoteru Noguchi, Hitoshi Ohtake, Yoshimitsu Takagi, Takuya Yamaguchi, Yoshiaki Saito, Yasuaki Takebe
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Patent number: 8216512Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: GrantFiled: December 19, 2003Date of Patent: July 10, 2012Assignee: DAKO Denmark A/SInventors: Lars Winther, Marc Key, Kristopher S. Buchanan, John Favuzzi, Benno Guggenheimer