Abstract: A module for processing fluids includes one or more collapsible fluid chambers supported on a substrate, a compression element supported on the substrate and configured to be movable with respect to the one or more chambers, and an actuating element coupled to the compression element and configured to effect movement of the compression element relative to the one or more fluid chambers to collapse each fluid chamber by compressing the fluid chamber between the compression element and the substrate as the compression element moves over the fluid chamber.

Abstract: A urea sensor protection assembly for protecting a fluid sensor of a urea sensor system comprises an inner cage supporting the fluid sensor and an outer cage. The inner cage has a first fixation element fixing the inner cage to a common holder. The outer cage has a filter capable of blocking a plurality of air bubbles and/or allowing a fluid to pass and a second fixation element fixing the outer cage to the common holder. The inner cage is at least partially arranged in an inner volume of the outer cage in an assembled state.

Abstract: An apparatus for diagnosing deterioration of an NOx storage-reduction catalyst for purifying an exhaust gas discharged from an internal engine, including an intake air amount detection unit for detecting an intake air amount to the internal combustion engine, an exhaust gas temperature detection unit for detecting the temperature of an exhaust gas passing through the NOx storage-reduction catalyst, an NOx purification rate detection unit for detecting NOx in an exhaust gas flowing into the NOx storage-reduction catalyst and in an exhaust gas flowing out of the NOx storage-reduction catalyst, thereby detecting an NOx purification rate, and a diagnostic unit for, when the temperature of the exhaust gas passing through the NOx storage-reduction catalyst increases following an increase in the intake air flow rate to the internal combustion engine and in turn, the temperature of the NOx storage-reduction catalyst greatly increases over a first predetermined threshold value, calculating a difference in the NOx puri

Abstract: In accordance with an embodiment of a system for handling and processing chemical and/or biological samples, a MicroChamber comprises a substrate, a reservoir formed on the substrate for receiving a chemical and/or biological sample, and an encoder such as a barcode or other suitable device. The encoder encodes information describing at least one characteristic of the substrate and/or reservoir.

Abstract: A sorption exothermicity measurement device (1) mainly includes: an air pump (2) that supplies dry air; a bubbling instrument (3) that humidifies dry air and supplies humidified air; a reaction measuring instrument (4) into which air flows so that the dry air or the humidified air comes in contact with a sample (10) to be measured; and a flow rate measuring instrument (5) that measures the flow rate of at least the humidified air flowing into the reaction measuring instrument (4). The reaction instruments are connected by flow paths through which the dry air or the humidified air flows. Furthermore, at least a humidified air supply system needle valve (13) that regulates the flow rate of the humidified air is included.

Abstract: A biological test device with at least one zone containing a biosensor and/or reagent media to accept a sample of a biological material, where the zone is covered until use by a removable humidity resistant cover. The cover may be slidably removable or have a peel-off configuration and may incorporate a desiccant material. The cover may also act as an actuator associated with electronic timing and/or signalling components carried by the device.

Abstract: The invention relates to a heated reaction chamber for processing a biochip and to a method for controlling said reaction chamber. The heated reaction chamber for processing a biochip comprises a chamber wall, constituted by a flexible circuit board (10), a circuit path (10.3) being configured on the flexible circuit board (10) and being used as the heating device. The use of a flexible circuit board as the wall of a reaction chamber allows for a low thermal capacity of the reaction chamber in the area of the heating device, thereby allowing the chamber to be heated up quickly.

Abstract: A vacuum assist apparatus can comprise a microplate. The microplate can comprise a first surface and an opposing second surface. A plurality of wells can be formed in the first surface of the microplate. Each of the plurality of wells can be sized to receive an assay therein. A support base can comprise a fluid passage. The microplate can be positioned adjacent and in contact with the support base. A pressure device, in fluid communication with the fluid passage, can exert a vacuum within the fluid passage to actively retain the microplate in the contact with the support base.

Abstract: A partition wall is provided between a display section and a sensor mount inside a main case. A control board housing chamber is disposed on the display unit side of the partition wall, and a measurement board housing chamber is disposed on the sensor mount side of the partition wall. A control board is housed in the control board housing chamber, and a measurement board and a temperature sensor are housed in the measurement board housing chamber.

Abstract: A sensor chip is configured to measure the temperature of a blood sample and includes a capillary section and an electrode unit. The capillary section allows the blood sample to be introduced therein. The electrode unit is configured to measure the temperature of the blood sample and includes a working electrode and a counter electrode. The working electrode and the counter electrode respectively include a reaction reagent layer containing an electrolyte. Further, the electrode unit is configured to receive a predetermined voltage to be applied in measuring the temperature of the blood sample for allowing a result of the measurement to be less affected by increase and reduction in a glucose concentration and the like.

Abstract: This invention describes an advanced cooling system for a laboratory instrument to maintain laboratory samples at a predetermined temperature. The advanced cooling system uses an algorithm that incorporates information from at least one sensor and other operational parameters including thermal effects from the operation of the instrument.

Abstract: The measurement device comprises a sensor holder to which is removable to a biosensor. The sensor holder has measurement-use connection terminals that are in contact with the electrode system in the biosensor and are used to take off signals required for measuring the specific component, and thermocouple-use connection terminals that are in contact with the thermocouple in the biosensor and are used to take off the thermoelectromotive force signals.

Abstract: A system for managing power consumption of a handheld diabetes management device and limiting effects of temperature on operations performed by the handheld diabetes management device comprises a blood glucose measuring module, a temperature sensing module, and a power management module. The blood glucose measuring module selectively measures blood glucose in a blood sample and generates a status signal indicating a status of operation of the blood glucose measuring module. The temperature sensing module senses an internal temperature of the handheld diabetes management device and estimates an ambient temperature external to the handheld diabetes management device. The power management module deactivates one or more components of the handheld diabetes management device based on the status of operation of the blood glucose measuring module when the internal temperature of the handheld diabetes management device exceeds a threshold temperature.

Abstract: A biosensor system determines analyte concentration from an output signal generated by an oxidation/reduction reaction of the analyte. The biosensor system adjusts a correlation for determining analyte concentrations from output signals at one temperature to determining analyte concentrations from output signals at other temperatures. The temperature-adjusted correlation between analyte concentrations and output signals at a reference temperature may be used to determine analyte concentrations from output signals at a sample temperature.

Abstract: The present invention includes a body case having a biological sample sensor mounting portion on one end side, a temperature sensor (A) provided on the one end side inside the body case, a measurement portion connected to the biological sample sensor mounting portion, and a control portion connected to the measurement portion. A temperature sensor (B) is provided on one other end side inside the body case, and when measurement is performed by the measurement portion, temperature change amounts in the two end portions are compared using the temperature sensors (A) and (B).

Abstract: A high temperature furnace comprising hot zone insulation having at least one shaped thermocouple assembly port to reduce temperature measurement variability is disclosed. The shaped thermocouple assembly port has an opening in the insulation facing the hot zone that is larger than the opening on the furnace shell side of the insulation. A method for producing a crystalline ingot in a high temperature furnace utilizing insulation having a shaped thermocouple assembly port is also disclosed.

Abstract: The invention relates to a microelectronic sensor device and a method for the investigation of biological target substances (20), for example oligonucleotides like DNA fragments. In one embodiment, the device comprises a reaction surface (RS) to which target specific reactants (10) are attached and which lies between a sample chamber (SC) and an array of selectively controllable heating elements (HE). The temperature profile in the sample chamber (SC) can be controlled as desired to provide for example conditions for a PCR and/or for a controlled melting of hybridizations. The reactant (10) and/or the target substance (20) comprises a label (12) with an observable property, like fluorescence, that changes if the target substance (20) is bound to the reactant (10), said property being detected by an array of sensor elements, for example photosensors (SE).

Abstract: Provided is a temperature sensitive indicator, which can be held in a desired state and is not affected by temperature of a finger at the time of an operation of the temperature sensitive indicator. The temperature sensitive indicator includes: a member base (13) including an upper base member (11) and a lower base member (12); and a label component (21) sandwiched and held between the upper base member and the lower base member of the member base under a state in which a pulled-out portion on one end side of the label component is protruded outward.

Abstract: An apparatus for detecting a chemical of interest in a fluid or estimating a concentration of the chemical in the fluid includes: a carrier configured to be conveyed through a borehole penetrating an earth formation; a first temperature sensor disposed at the carrier and configured to sense a temperature of the fluid and provide a first temperature output; and a second temperature sensor disposed at the carrier and covered with an exothermic reaction material that experiences an exothermic reaction when exposed to the chemical of interest and configured to sense a temperature and provide a second temperature output. The apparatus further includes a processor coupled to the first temperature sensor and the second temperature sensor and configured to detect the chemical or estimate the concentration using the first temperature output and the second temperature output.

Abstract: Embodiments described herein provide micro-fluidic systems and devices for use in performing various diagnostic and analytical tests. According to one embodiment, the micro-fluidic device includes a sample chamber for receiving a sample, and a reaction chamber for performing a chemical reaction. A bubble jet pump is structured on the device to control delivery of a fluid from the sample chamber to the reaction chamber. The pump is fluidically coupled to one or more chambers of the device using a fluidic channel such as a capillary. A valve may be coupled to one or more chambers to control flow into and out of those chambers. Also, a sensor may be positioned in one or more of the chambers, such as the reactant chamber, for sensing a property of the fluid within the chamber as well as the presence of a chemical within the chamber.

Abstract: A method for analyzing a fluid containing one or more analytes of interest includes; measuring a plurality of properties of a sample fluid with unknown concentrations of the one or more analytes of interest; and using the measurements and a model of the relationship between the plurality of properties and concentrations of the one or more analytes to calculate the concentration of at least one of the analytes of interest. The model may be an artificial neural network. The method may be used to monitor the concentration of inhibitors of gas hydrate formation in a fluid. Apparatus for use in the method is also provided.

Abstract: Sensors for the detection of free radicals and free radical forming compounds including, for example, peroxides, as well as energetic radiation, UV light, plasma or heat each such sensor including a functional component are described herein. In addition, this disclosure includes methods for making such sensors and methods for using sensors including a functional component and devices incorporating such sensors.

Abstract: A system for storing ammonia comprises gas detector that is able to detect gases other than ammonia. The system further comprises thermally activatable ammonia stores, which can be activated to release ammonia upon heating. When the ammonia stores are not heated, the system is below ambient pressure and any leak will cause external gas to enter the system. Therefore, the gas detector is used to detect the presence of such external gas, which allows to detect leaks. The gas detector may be embodied as a thermal detector using a single heater and two temperature sensors for detecting a gas flow as well as external gas.

Abstract: The invention concerns an analyzer, typically for analyzing body fluids, which has one or several exchangeable cassettes (consumables) that contain operating liquids, operating materials and/or consumables and can be inserted into corresponding holders of the analyzer, wherein the analyzer has a system for exchanging ambient air which has a filter unit on the inlet side of the analyzer to filter the ambient air that needs to be exchanged. The filter unit is integrated into at least one of the exchangeable cassettes in order to minimize the amount of maintenance for the analyzer.

Abstract: A control system of a NOx removal device is provided with reagent introducing means for introducing a reagent into a fluid, a temperature measuring device that measures a temperature distribution of the fluid, a reagent-concentration calculating portion that calculates a concentration distribution of the reagent introduced into the fluid with the temperature distribution determined at the temperature measuring device, a reagent-flow-rate determining portion that determines a flow rate of the reagent that the reagent introducing means introduces in accordance with the concentration distribution calculated at the reagent-concentration calculating portion, and a reagent-introducing-means control portion that controls the reagent introducing means so as to introduce the reagent into the fluid at the flow rate determined at the reagent-flow-rate determining portion.

Abstract: A sensor chip includes two measuring units. The first measuring unit includes an electrode system having a portion of an electrode and a portion of an electrode, and a portion of a capillary containing the portion and the portion. The second measuring unit includes an electrode system having a portion of a sensor electrode and a portion of an electrode, and a portion of a capillary containing the portion and the portion in addition to a reaction reagent layer. Data related to the temperature of the blood sample is acquired based on the dimension of a current flowing through the temperature electrodes, and data related to a concentration of an analyte in the blood sample is acquired based on the dimension of a current flowing through the analysis electrodes.

Abstract: The invention relates to different designs of a microelectronic device comprising an array of heating elements (HE) with local driving units (CU2) and optionally with an array of sensor elements (SE) adjacent to a sample chamber (SC). By applying appropriate currents to the heating elements (HE), the sample chamber can be heated according to a desired temperature profile. The local driving units comprise means for compensating variations of their individual characteristics.

Abstract: An apparatus for synthesis and assaying of materials is provided that significantly improves throughput efficiency by allowing for material synthesis and assaying in the same assembly while possessing the ability to reach higher pressures and higher temperatures than existing designs capable of synthesis and assaying in the same assembly. In addition, the apparatus provides for gas flow over the material sample, allowing for a number of materials to be synthesized within the apparatus by gas synthesis.

Abstract: Apparatus for conducting and monitoring chemical reactions comprises a base and a thermal cycler mounted on the base. A plurality of heat-conducting receptacles are mounted on the thermal cycler and in heat-communication therewith. Each receptacle comprises an opaque body defining a bore having an open end, a first window, and a second window. A cartridge is removably mounted on the receptacles. The cartridge comprises a plurality of light-transmitting reaction vessels, and conduits connected to the reaction vessels for processing and transferring fluid. The reaction vessels are received in the bores of the receptacles through the open ends of the bores. A light emitter is mounted on the base for illuminating the reaction vessels through the first windows of the reaction vessels. A light detector is mounted on the base for selectively receiving and detecting light emitted from the reaction vessels through the second windows of the receptacles.

Abstract: Apparatus for detecting deterioration of an NOx selective reduction catalyst in an exhaust passage of an internal combustion engine with improved accuracy, includes an NOx purification rate calculation unit for calculating the NOx purification rate in the NOx selective reduction catalyst based on the NOx concentration in the exhaust gas flowing into and out of the NOx selective reduction catalyst. A determination as to whether the NOx selective reduction catalyst is deteriorated is made based on the NOx purification rate at a time when the temperature of the NOx selective reduction catalyst is equal to or higher than a temperature (Tc0) at which the NOx purification rate will start to decrease with a rise in the temperature of the NOx selective reduction catalyst if the degree of deterioration of the NOx selective reduction catalyst is at the upper limit of an allowable range.

Abstract: A method and apparatus for observing a biological microelectromechanical systems response to a fluid including combining an activator and a fluid wherein the fluid comprises a component from a subterranean formation, exposing the combined activator and fluid to a sensor in a wellbore to observe a biological microelectromechanical systems response, and integrating data from the observing with petrophysical data. A method and apparatus for observing a biological microelectromechanical systems response to a fluid including a housing comprising a biological microelectromechanical observation material, a signal analyzer in communication with the material, and a fluid preparation device positioned to allow fluid to flow to the surface, wherein the fluid comprises a component from a subterranean formation.

Abstract: A method and device for merging and mixing at least two separate and distinct fluid drops on a substrate, includes a drop merging area on the surface, where a first magnetic material is placed at a first location. A first drop of fluid is then placed at the first location on the surface, resulting in the first magnetic material being at least partially positioned within the first drop of fluid. A second drop of fluid is then placed at a second location on the surface of the drop merging area. A magnetic field is applied by a varying magnetic field generator to at least a portion of the drop merge area of the substrate, which includes at least the first location on the substrate. The varying magnetic field will act on the first magnetic material to move the first magnetic material within the first drop of fluid, causing a stirring of the fluid. A drop merging force from a drop merging mechanism is applied to at least one of the first drop of fluid and the second drop of fluid within the drop merge area.

Abstract: An assembly determines an analyte concentration in a sample of body fluid. The assembly includes a test sensor having a fluid-receiving area for receiving a sample of body fluid, where the fluid-receiving area contains a reagent that produces a measurable reaction with an analyte in the sample. The assembly also includes a meter having a port or opening configured to receive the test sensor; a measurement system configured to determine a measurement of the reaction between the reagent and the analyte; and a temperature-measuring system configured to determine a measurement of the test-sensor temperature when the test sensor is received into the opening. The meter determines a concentration of the analyte in the sample according to the measurement of the reaction and the measurement of the test-sensor temperature.

Abstract: An internal temperature sensor for measuring internal temperature of a case of the blood glucose meter is arranged inside the case of the blood glucose meter, and an external temperature sensor configured by components with low heat capacity and adapted for measuring external temperature is arranged at a position separated from the central portion of the case of the blood glucose meter. Further, a microcomputer of the blood glucose meter includes the following processing: judging whether or not the temperature fluctuation falls within the acceptable range based on the difference between the respective temperatures and, if the temperature fluctuation exceeds the acceptable range, temporarily stopping the processing until the temperature fluctuation falls within the acceptable range when in the case where the blood glucose measurement has not yet been performed, or stopping the blood glucose measurement processing when in the case where the blood glucose measurement is being performed.

Abstract: Embodiments described herein provide micro-fluidic systems and devices for use in performing various diagnostic and analytical tests. According to one embodiment, the micro-fluidic device includes a sample chamber for receiving a sample, and a reaction chamber for performing a chemical reaction. A bubble jet pump is structured on the device to control delivery of a fluid from the sample chamber to the reaction chamber. The pump is fluidically coupled to one or more chambers of the device using a fluidic channel such as a capillary. A valve may be coupled to one or more chambers to control flow into and out of those chambers. Also, a sensor may be positioned in one or more of the chambers, such as the reactant chamber, for sensing a property of the fluid within the chamber as well as the presence of a chemical within the chamber.

Abstract: Among others, the present invention provides micro-devices for detecting or treating a disease, each comprising a first sorting unit capable of detecting a property of the biological subject at the microscopic level and sorting the biological subject by the detected property; a first detection unit capable of detecting the same or different property of the sorted biological subject at the microscopic level; and a first layer of material having an exterior surface and an interior surface, wherein the interior surface defines a first channel in which the biological subject flows from the first sorting unit to the first detection unit.

Abstract: The reaction chip of the present invention has a plurality of recesses 6 constituting a part of a reaction container and a groove constituting a part of a channel formed on at least one of one face of a first base material (resin base material 2) and one face of a second base material (metallic base material) and a notch 15 showing a gradual increase in width and a gradual increase in depth from one face 2d of the base material toward an inner wall surface 6d of the recess is formed on an edge of at least one recess in an extending direction of the groove. One face of the first base material and one face of the second base material are stuck together opposite to each other to form the plurality of reaction containers and the channel.

Abstract: A biosensor system determines analyte concentration from an output signal generated by an oxidation/reduction reaction of the analyte. The biosensor system adjusts a correlation for determining analyte concentrations from output signals at one temperature to determining analyte concentrations from output signals at other temperatures. The temperature-adjusted correlation between analyte concentrations and output signals at a reference temperature may be used to determine analyte concentrations from output signals at a sample temperature.

Abstract: Determining a temperature experienced by a region of a component comprising the steps of: providing a component with a temperature sensitive detection material in a first state and exhibiting a first chemical characteristic prior to its exposure to a thermal environment; exposing the component to a thermal environment such that the detection material is converted to a different state in which at least one region of the detection material exhibits at least one chemical characteristic different to the first chemical characteristic; identifying at least one region of the component in which the detection material exhibits the at least one chemical characteristic which is different to the first chemical characteristic; and determining the temperature experienced by the component in the or each region by relating the detection material chemical characteristic in the or each region to a temperature value by reference to a correlation of detection material chemical characteristic and temperature.

Abstract: An automatic chemical analyzer in which a reaction solution is stirred by air ejected from an air ejection hole placed above a reaction container. The reaction region can be washed and cleaned sufficiently without causing damage, such as exfoliation of a coating reagent. A reaction container disk is provided with a pore and a pressure detector connected with the pore. Before and after the stirring operation, the ejection hole (nozzle) ejecting air is moved and the output value of the pressure detector is compared with a previously measured normal value. With a discharge pipe and a suction pipe inserted to the opening of the reaction container to be close to both ends of the opening and the side wall of the container, the reaction region at the bottom of the container is washed by continuous discharge and suction of cleaning fluid.

Abstract: With this device for measuring a biological sample, a partition wall (14) is provided between a display section (2) and a sensor mount (5) inside a main case (1). A control board housing chamber (15) is disposed on the display unit (2) side of the partition wall (14), and a measurement board housing chamber (16) is disposed on the sensor mount (5) side of the partition wall (14). A control board (6) is housed in the control board housing chamber (15), and a measurement hoard (7) and a temperature sensor (13) are housed in the measurement board housing chamber (16).

Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.

Abstract: An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.

Abstract: In order to provide a sensor operating in a high sensitivity at a low cost and a radio sensor platform having a high energy efficiency, the sensor includes a detecting film which generates heat through incidence or adhesion of an object, a magnetic film which generates a spin current in a direction of a temperature gradient by the heat generated by the detecting film, and an electrode which convert the spin current generated by the magnetic film into an electric current.

Abstract: A sample measurement device (110), in which a biosensor (30) having an electrode is mounted, voltage is applied to the electrode, and the concentration of a specific component in a sample deposited on the biosensor (30) is measured, comprises a voltage source (19) configured to apply voltage to the electrode, a time measurement component (22), and a controller (18) configured to control the voltage to be applied and measure the concentration of the specific component. The time measurement component (22) measures a detection time, which is the length of time between the mounting of the biosensor (30) and the deposition of a sample on the biosensor (30). The controller (18) changes a set value for measuring the concentration of a specific component according to the detection time. Consequently, measurement accuracy can be improved regardless of the temperature of the biosensor (30).

Abstract: The invention is characterized in that it has a layer of organic material sensitive to changes in pressure, voltage, deformation, gases and/or temperature; wherein said organic layer consists of at least one conductive salt or complex including a molecule A and a dopant D, said molecule A being an electron donor or acceptor organic molecule or macromolecule capable of forming a conductive salt or complex, which without doping is not conductive, and with the presence of dopant D becomes a compound that is donor or acceptor of electrons and capable of forming conductive salt or complex with the molecule or macromolecule A; and a base substrate, in close contact with said layer of organic material. The sensor device is useful in molecular electronics or plastic electronics, in particular, in the field of organic sensors.

Abstract: An assembly determines an analyte concentration in a sample of body fluid. The assembly includes a test sensor having a fluid-receiving area for receiving a sample of body fluid, where the fluid-receiving area contains a reagent that produces a measurable reaction with an analyte in the sample. The assembly also includes a meter having a port or opening configured to receive the test sensor; a measurement system configured to determine a measurement of the reaction between the reagent and the analyte; and a temperature-measuring system configured to determine a measurement of the test-sensor temperature when the test sensor is received into the opening. The meter determines a concentration of the analyte in the sample according to the measurement of the reaction and the measurement of the test-sensor temperature.

Abstract: Systems and methods are disclosed herein for a microfluidic calorimeter apparatus. A microfluidic calorimeter system includes a calorimetry apparatus and a processor in connection with the apparatus. The apparatus includes a microfluidic laminar flow channel connected to two inlets for flowing fluid into the laminar flow channel. Below the laminar flow channel is a plurality of microscale temperature sensors at known positions in the channel. The processor is in connection with the discrete temperature sensors and determines a calorimetry measurement based on local temperatures derived from data output by the microscale temperature sensors and the respective positions of the sensors in the channel.

Abstract: The invention provides an apparatus for regulating the temperature of a chemical and/or biological sample and a method of using the same. The apparatus includes at least one temperature control module. The temperature control module includes a heater, a conductor of caloric, and a temperature sensor. The heater of the temperature control module is adapted to thermally communicate with a removable substrate, on which said chemical and/or biological sample is placed, via the conductor of caloric. The temperature sensor of the temperature control module is adapted to detect and control the temperature of the substrate via the conductor of caloric. The apparatus is designed such that the substrate is situated above said temperature control module to entirely cover said temperature control module.

Abstract: The invention relates to continuous flow systems, in particular thermocyclers for the automated and continuous cycling of fluid between a plurality of temperature zones in the amplification of nucleic acids. The invention also relates to an improved sample port for introducing a volume of a liquid sample into a continuous flow system.