Abstract: A biological fluid separation device and a separation process that allows for efficient separation of plasma from a blood sample is disclosed. A biological fluid separation device of the present disclosure is adapted to receive a blood sample having a cellular portion or cells and a plasma portion or plasma. A biological fluid separation device of the present disclosure separates plasma from cells using a track-etched membrane and cross-flow filtration.

Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a plurality of processing vessels and a collector. The collector funnels portions of the target material from the suspension through a cannula and into the processing vessels. Sequential density fractionation is the division of a sample into fractions or of a fraction of a sample into sub-fractions by a step-wise or sequential process, such that each step or sequence results in the collection or separation of a different fraction or sub-fraction from the preceding and successive steps or sequences. In other words, sequential density fractionation provides individual sub-populations of a population or individual sub-sub-populations of a sub-population of a population through a series of steps.

Abstract: A medical device may include a needle, including a plurality of links and a distal tip, reciprocally movable between a first configuration and a second configuration, and a conduit including a lumen extending through the needle, the conduit being coupled to the distal tip, wherein longitudinal movement of the conduit is configured to transition the needle between the first configuration and the second configuration.

Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. An enrichment agent may be added to a vessel that contains the sample for positive selection, or, in other words, to select or aid in selecting the target material from amongst the remainder of the sample. The enrichment agent may be, for example, immunomagnetic beads, buoyant beads, high-density beads, chemicals to change the density of the target material, or the like.

Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a displacement fluid, a collector, and a primary vessel. In another implementation, the system includes a processing vessel, a displacement fluid, a collector, and a primary vessel.

Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. A first depletion agent may be added to a vessel that contains the sample to change the density of a non-target material.

Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a plurality of processing vessels and a collector. The collector funnels portions of the target material from the suspension through a cannula and into the processing vessels. Sequential density fractionation is the division of a sample into fractions or of a fraction of a sample into sub-fractions by a step-wise or sequential process, such that each step or sequence results in the collection or separation of a different fraction or sub-fraction from the preceding and successive steps or sequences. In other words, sequential density fractionation provides individual sub-populations of a population or individual sub-sub-populations of a sub-population of a population through a series of steps.

Abstract: Provided is a biomaterial detecting device for confirming or detecting a biomaterial reaction, and more particularly to a biomaterial detecting device, which is formed in a stick type to thereby be immersed in a tube containing a biomaterial solution to be tested; has an upper portion with a cap structure to thereby induce reaction with a biomaterial, and thus facilitate confirmation and detection of the biomaterial; and is formed in a cap structure to thereby prevent evaporation of a sample and infiltration of an external material at the time of a biomaterial reaction in the tube, and thus improve reliability in analysis.

Abstract: A test tube insert includes a flange having a width greater than a width of a mouth of a larger test tube into which the insert is to be inserted. The flange defines a first central opening. An annulus extends integrally downward from the flange. The annulus includes a fenestrated wall and a floor defining a second central opening. A small test tube body, smaller than the larger test tube, extends integrally downward from the floor of the annulus with the second central opening forming a mouth of the small test tube body. The test tube insert is disposed in the mouth of the larger test tube. Fluid is transferred through the central opening and the fluid fills the small test tube body of the test tube insert and flows through the fenestrated wall once the small test tube body is full into the larger test tube.

Abstract: A vessel including an identification region may be placed in a holder. Through interaction of a positioning feature on the vessel and an orientation feature on the holder, the vessel can be placed into an alignment orientation, e.g., such that the identification region may be reliably read by a reader. The identification region may provides information related to the sample, such as vessel identity, sample volume, processes to be performed on the sample, and so on.

Abstract: Polymer compositions and articles formed therefrom are described herein. The compositions include a random copolymer and a radiation additive, wherein the random copolymer includes propylene and less than 2 wt. % ethylene and exhibits a melt flow rate of from about 30 to 100 dg/min., the polymer composition exhibits a flexural modulus of from about 160 kpsi to about 200 kpsi and the polymer composition is adapted to produce a polymer article exhibiting low plate out, a haze at 20 mils of no greater than 15%, radiation stability and autoclavability.

Abstract: A reagent tube configured with a stellated shaped pattern, on its bottom interior surface, configured to facilitate complete or near-complete withdrawal of fluid from the tube, via a pipette tip. The reagent tube may be used for transporting reagents and for carrying out processing operations on biological samples with the reagents, such as preparing polynucleotides extracted from the sample for amplification.

Abstract: Plastic test tube for taking blood samples, comprising a hollow tubular body and an adhesive protective film able to adhere to the tubular body. The tubular body is made of polyethylene terephthalate and has: a tubular wall which delimits a working volume and defines an outer surface; an open mouth for insertion of liquids at a first end of the wall; and a bottom for closing a second end of the wall. The adhesive protective film is able to adhere to the wall of the tubular body over at least a portion of the outer surface. The test tube is characterized in that the wall of the tubular body has a thickness in the range of 1 to 3 mm and in that the protective film is defined by a layer of polypropylene, polyethylene or copolymers thereof. The layer has a thickness in the range of between 40 and 60 ?m and is able to form a liquid barrier.

Abstract: Multiple-component integral-structure dual-test sterility indicator, method of assembling physical components, selected spores, and chemical constituents in solution, within the indicator and arranged to enable dual-evaluations of bacterial-lethality of a dry-goods load, resulting from exposure to a selected saturated-steam sterilizing cycle. The chemical constituents are formulated to chemically produce reaction-product, which is quantitatively responsive to the combined effect of cycle steam temperature and time of exposure at that temperature, for providing a promptly-available spectroscopic evaluation of bacterial-lethality. Absorption of narrow-band selected visible-light wavelength by reaction-product, if any, of chemical-constituent solution, is used to quantitatively measure that combined-effect exposure.

Abstract: Vial comprising an outer vial and an inner vial, wherein in the space enclosed between the inner vial and the outer vial a memory chip is included, characterized in that the inner vial and outer vial are connected to each other with the aid of a connecting ring, such that they are detachable from each other, the connecting ring forming a seal in that this can only be broken by destruction, the memory chip being connected to the outer vial. The invention also relates to a method for the use of a vial for the purpose of performing an analysis on a sample and to a system for practicing the method using vials according to the invention.

Abstract: A method of uniquely identifying a plurality of discrete test tubes. The method includes providing a rack having an array of wells located at the intersections of mutually perpendicular columns and rows. The rack is marked to orient the rack from top to bottom and left to right. Each well is identifiable by reference to a sequence of letters and numbers identifying its respective intersecting column and row. A plurality of test tubes are positioned in the wells. The test tubes have open tops and closed lower ends protruding through the open bottoms of the wells. Indicia are applied to the respective closed lower ends of the test tubes positioned in the wells. The application of the indicia is performed in situ and simultaneously as a single step to all of the test tubes in the wells, thereby resulting in each test tube being uniquely identified with reference to its respective well.

Abstract: A method of identifying and arranging test tubes, which includes providing a rack having an array of wells located at the intersection of mutually perpendicular columns and rows. The columns and rows are aligned on perpendicular edges of the rack. The test tubes are positioned in the wells and then marked with indicia to correspond to the location of the respective wells.

Abstract: A non-light penetrating phlebotomy tube comprising a dark colored hollow tubular housing having an elongated cylindrical member wherein one distal end of the elongated cylindrical member is rounded and the other distal end of the elongated cylindrical member is open. A hermetic sealing member is received in the other distal end of the elongated cylindrical member for sealing the hollow tubular housing. The non-light penetrating phlebotomy further comprises a temperature sensitive level indicator coupled to the elongated cylindrical member for detecting the level of a fluid entering the dark colored hollow tubular housing.

Abstract: A nonwoven fabric having high performance aqueous fluid retention and wiping characteristics and a method of producing such fabric. The fabric comprises a reinforcing web of self-bonded continuous filament synthetic fibers having at least one surface with spaced clusters of synthetic staple fibers and short natural fibers generally surrounded by void areas having a concentration of synthetic staple fibers and short natural fibers which is lower than such concentration in the clusters. The desired pattern of clusters may be obtained by hydroentanglement using a coarse apertured forming surface.