Abstract: Novel antimicrobial compositions and coatings are disclosed. The antimicrobial compositions consist of mixtures of taurolidine and protamine, including protamine salts. The antimicrobial compositions are particularly useful in coatings for implantable medical devices. The antimicrobial compositions are effective against a broad spectrum of microbes.

Abstract: The invention is directed to a wound healing device. Such wound healing device utilizes novel wound healing compositions embedded onto or into a natural plant-derived cloth-based matrix.

Abstract: A disposable paper towel with an anti-microbial lotion and is provided with a chromatic transfer indicator which undergoes a delayed, visually perceptible color change at a predetermined time after the towel is wetted. An anti-microbial lotion on the towel increases water absorbency times (WAR) to further promote lotion transfer to the skin and increase lotion transfer effectiveness.

Abstract: Articles of clothing treated with bacteria adapted to metabolize a component selected from the group consisting of ammonia, ammonium salts, or urea into any of nitric oxide, nitric oxide precursors, and combinations thereof are provided.

Abstract: The present invention is directed to a composition comprising i) a microencapsulated pesticide, ii) a dispersant selected from the group consisting of a lignin, b) a lignosulfonate salt and c) a lignosulfonate salt combined with the sodium salt of substituted naphthalene sulfonate formaldehyde polymer, iii) a salt selected from the group consisting of magnesium sulfate, sodium chloride, sodium nitrate and calcium chloride, and iv) a non-encapsulated pesticide. The present invention is also directed to methods of making and using the compositions of the present invention.

Abstract: Disclosed are a sedative for external use, and sedative sheet, and textile, clothing, wall material, and hyperthermia equipment, brain vitalization sheet, brain vitalization small pillow which are with high productivity, adaptive for various shape and various treatment style for patients with pain, and with high treatment effect, comparing with conventional sedative for external use. A sedative for external use 10 is provided which is a bag 2 containing desert rose powder 1 prepared by pulverizing desert rose.

Abstract: Disclosed is a cooling sensation agent composition or sensory stimulation agent composition which contains at least one of diester compounds of dicarboxylic acid represented by the formula (1) wherein A represents CH2 or CH?CH, n represents an integer of 0 to 4 when A is CH2, or 1 when A is CH?CH, B is an alcohol residue having 10 to 18 carbon atoms and containing a para-menthane skeleton, which may have a substituent, and C is an alcohol residue having 6 to 18 carbon atoms, which may have a substituent as well as a flavor or fragrance composition, a beverage, a food product, a perfume or cosmetic product, a toiletry product, daily utensil products or groceries, a fiber, a fiber product, clothes, clothing or a medicine, wherein the cooling sensation agent composition or the sensory stimulation agent composition is compounded.

Abstract: The present invention relates to a keratotic plug remover composition including a polymer compound having a salt-forming group, and (a) an amino-modified silicone and/or (b) a polyoxyalkylene/dimethyl polysiloxane block copolymer, and a sheet for removing keratotic plugs including a nonwoven fabric substrate impregnated with the above composition. The keratotic plug remover composition and the sheet for removing keratotic plugs according to the present invention are enhanced in keratotic plug removing effect without increasing a pain of users when peeling the sheet pack from the skin.

Abstract: Skin care or cleansing implements are described containing a liquid, semi-solid or solid cleansing or skin treatment composition that is releasably associated with the implement. The composition is substantially nonaqueous and has a continuous and a discontinuous phase. Components of the discontinuous phase can react with each other or with water when water is blended with the nonaqueous cleansing or skin treatment composition during consumer use. Methods for treating the skin with the inventive implements are also described.

Abstract: The present invention describes a novel antibacterial treatment on textile materials using polymeric core-shell particles dispersing in water. These particles are prepared from a surfactant-free emulsion polymerization according to the method of U.S. Pat. No. 6,573,313 and have average particle sizes in the range of 100 to 1000 nm in diameter. When applied to a textile article, the particles form a uniform coating, which prevents the growth of bacteria and microbes. The treatment does not affect the fabric mechanical properties, hand feeling and appearance. Antibacterial activity on cotton is maintained even after 50 times of home laundering.

Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.

Abstract: Antimicrobial film based on biopolymers, in particular cellulose and/or protein, or uncoated or coated textile material, and also an antimicrobial sponge or an antimicrobial sponge cloth based on regenerated or precipitated cellulose are provided. The film, the sponge or the sponge cloth is impregnated or coated with at least one ?-amino acid ester, the ?-amino group of which is acylated with a fatty acid, or the corresponding hydrochloride, and the ?-amino acid ester is bound covalently, optionally also ionically, to the film, the sponge or the sponge cloth. The acylated ?-amino acid ester is preferably N-lauroyl-L-arginine ethyl ester monohydrochloride (LAECl), N-lauroyl-L-arginine methyl ester monohydrochloride (LAMCl) or N-lauroyl-L-lysine ethyl ester hydrochloride (LLECl). The film is preferably in the form of a flexible tube and is provided as casing for foods, especially sausage products.

Abstract: Tissues useful in providing fibrous tissue products for skin contact, such as facial tissue, bathroom tissue, disposable handkerchiefs which comprise a volatile rhinological effective composition for delivery to human skin.

Abstract: The present invention relates to protecting a human from an infection using a disinfecting agent as described herein and a method for use thereof, more particularly to a rare earth-containing device for protecting a wound and a method for use thereof.

Abstract: A composition for treatment of hyperhidrosis is provided that contains an effective amount of an antiperspirant. In particular, one embodiment of the composition of the present invention includes an antiperspirant, at least one muscle relaxing agent, at least one peptide, and at least one botanical agent and the composition is applied to a substrate. In another non-limiting illustration, the composition includes from about 0.001 to 50.0 vol % aluminum zirconium tetrachlorohydrex glycine and more preferably 19.0 vol %, glycerin, dipeptide diaminobutyroyl benzylamide diacetate, gamma amino butyric acid, solanum lycopersicum (tomato) extract, gynostemma pentaphyllum extract, panax ginseng root extract, portulaca oleracea extract, butylene glycol, denatured alcohol, and water.

Abstract: Disclosed are microcapsules and processes of microencapsulation of water soluble or water dispersible compounds by reverse-phase microencapsulation and ways to combine them with other oil soluble or oil dispersible compounds in suitable formulations that yield tiny microcapsules and a very homogeneous distribution of particle size. Multiple combinations of these reverse-phase microcapsules are disclosed, including in combination with normal-phase microcapsules in order to create a Capsule Mixed Suspension (CX) where an outer oil phase or, alternatively, a water phase contains microcapsules of two types: those with a core of water and active ingredients dissolved or dispersed therein, and those with a core of oil and active ingredients dissolved or dispersed therein. Water Dispersible Granules (WDG) and Emulsion Concentrates (EC) and Suspension Concentrates (SC) combinations with the reverse phase microcapsules are also successfully performed.

Abstract: The present invention is directed to a reinforced absorbable hemostat comprising at least one hemostatic agent in a single layer of nonwoven synthetic fabric having a mixture of compressed fiber staples of a polyglycolide/polylactide copolymer and a polydioxanone.

Abstract: Methods and apparatus for a human sample (S), analyzing the sample (S) and then determining a match with a member of the opposite sex is disclosed. In one embodiment, a customer purchases an AromaMatch™ Test Kit (14), which comprises a bottle of cleaning solution (20), a cotton ball (22) a sample patch (24), a sample bag (28) and a mailing envelope (30). The user (10) opens the kit (14), cleans a patch of skin somewhere on his or her body, and then applies the patch (24). After wearing the patch (24) for an appropriate time period, the patch (24) is removed, and placed in the sample bag (28). The user (10) writes his or her password on the sample bag (28), and then mails it in the return envelope (30). A laboratory analyzes the sample patch (24), and determines a set of genetic attributes (G1) that are associated with the sample (S). The user (10) receives an analysis report by mail, or views the results of the analysis on a website (18).

Abstract: The present invention relates to anti-atopic textiles, including a textile body and skin care layers formed by dyeing the textile body with a dyebath, obtained by filtering a mixture of earthworm powder and water through Korean paper. When clothes are made of the anti-atopic textiles and brought in contact with the skin, atopic dermatitis can be significantly alleviated because a moisturizing action and an anti-inflammation action are accelerated by a body composition and fluid components of earthworms included in the skin care layers and paper mulberry extract mixed from Korean paper. The anti-atopic textiles according to the present invention includes a textile body and skin care layers formed by dyeing the textile body with a dyebath which is obtained by mixing earthworm powder, obtained by pulverizing earthworms and drying the pulverized earthworms, and water and then filtering the mixture through Korean paper.

Abstract: The fiber structures in the form of a fiber (or fiber mass), woven or nonwoven fabric, fiber absorbent layers, mats or bats or other collection of fiber can be modified to be microbiocidal, bacteriostatic, obtain immobilized, microbes, etc. The disclosed fiber has the unique ability to capture and hold microbes or microbial generating units within the fiber mass.

Abstract: The invention relates to a patch for cutaneous application of a substance, the patch comprising a substance designed to penetrate the epidermis, means for placing the substance in contact with the skin and a peelable cutaneous exfoliation film enabling exfoliation of the skin, after placing the patch, at the level of the contact zone between said substance and the skin.

Abstract: Continuous processing methods for making absorbable polymeric non-wovens with one or more of the following properties: high burst strength, fine fibers of average diameter from 1 ?m to 50 ?m, and thickness from 10 ?m to 50 mm, have been developed. Improved fiber cohesion is made possible by allowing the fibers of the non-woven to initially remain molten during web collection. In the preferred embodiment, the polymer is a polyhydroxyalkanoate, and in the most preferred embodiment, the polymer comprises 4-hydroxybutyrate. A particularly preferred embodiment is a non-woven of poly-4-hydroxybutyrate or copolymer thereof, wherein the non-woven has a burst strength greater than 0.1 Kgf, wherein the non-woven is derived by a continuous melt-blown process. The non-wovens can be used for a variety of purposes including fabrication of medical devices.

Abstract: A delivery system for various functional compounds is disclosed. The delivery system incorporates a composition containing alumina. Various functional materials containing particular moieties may be adsorbed onto the alumina and used as desired. The functional compounds can be, for instance, pharmaceuticals, xenobiotics, anti-microbial agents, anti-viral agents, UV absorbers, odor control agents, fragrances, and the like. In one particular embodiment, for instance, certain dyes can be adsorbed onto the alumina surfaces. Once the dye is adsorbed onto the alumina surface, the resulting particles can be combined with a liquid vehicle for use in any suitable printing process.

Abstract: A silver composition comprising silver sulfate, methods of making antimicrobial articles, particularly packaged antimicrobial articles, methods of whitening antimicrobial articles, and packaged antimicrobial articles.

Abstract: A polymer latex composition has an acrylonitrile component, a polychloroprene component, and a natural latex component. When these components are blended together and formed into a film, the film exhibits a resistance to ozone that is greater than a resistance to ozone of materials in which acrylonitrile is not included. Furthermore, the combination of acrylonitrile and chloroprene imparts a synergistic effect to the composition with regard to ozone resistance. The film can be formed into a glove having a resistance to ozone that is improved over the resistance to ozone of gloves not including acrylonitrile. The glove may include an antimicrobial agent.

Abstract: A covalently crosslinked hydrogel comprises a) three or more divalent poly(alkylene oxide) chains P? covalently linked at respective first end units to a branched first core group C?, b) three or more divalent poly(alkylene oxide) chains P? covalently linked at respective first end units to a branched second core group C?, the chains P? comprising respective second end units which are covalently linked to between 0% and 100% of respective second end units of chains P? by divalent linking groups L?, and c) at least one pendant cationic block copolymer chain A?-B?. A?-B? comprises i) a divalent block A? comprising a poly(alkylene oxide) backbone chain having an end unit covalently linked to a second end unit of one of the chains P? by a divalent linking group L?, and ii) a monovalent block B? comprising a first repeat unit, the first repeat unit comprising a backbone carbonate group and a cationic side chain group.

Abstract: A method for treating acne on the skin. The method has the steps of (a) providing an drapeable or flexible porous article impregnated with an aqueous cleansing composition having a carrier, benzoyl peroxide, and one or more cleansing agents; (b) contacting an area of the skin affected by acne with the porous article such that the skin is contacted by the composition; and (c) removing the composition from the skin wherein residual benzoyl peroxide remains on the skin in an anti-acne effective amount. There are also anti-acne compositions.

Abstract: Morpholino compounds of Formula (I) wherein R1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, or pharmaceutically acceptable salts thereof, have been found to be surprisingly effective at promoting the healing of a wound.

Abstract: An isolated polypeptide comprising the amino acid sequence of serum paraoxonase (PON1) having catalytic efficiency of kcat/KM?106-5·107 M?1min?1 for a G-type organophosphate.

Abstract: A device is provided that allows for target treatment of neuropathy, such as diabetic peripheral neuropathy, or neuropathy and ulcers resulting from said neuropathy. The device comprises a nitric oxide (NO) eluting polymer arranged to contact a treatment area, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that the carrier material, in use, regulates and controls the elution of the therapeutic dosage of nitric oxide (NO). Furthermore, a corresponding manufacturing method for the device is disclosed.

Abstract: The present invention describes a novel antibacterial treatment on textile materials using polymeric core-shell particles dispersing in water. These particles are prepared from a surfactant-free emulsion polymerization according to the method of U.S. Pat. No. 6,573,313 and have average particle sizes in the range of 100 to 1000 nm in diameter. When applied to a textile article, the particles form a uniform coating, which prevents the growth of bacteria and microbes. The treatment does not affect the fabric mechanical properties, hand feeling and appearance. Antibacterial activity on cotton is maintained even after 50 times of home laundering.

Abstract: An anti-stick agent that may be incorporated into an aqueous medium to assist in the prevention of soils and bodily exudates adhering to the skin. A substrate may be utilized to assist in delivering the anti-stick agent to the skin.

Abstract: This invention provides an article of manufacture and method for controlling the application of a coupling agent, such as a silicone oil or mineral oil, on a surface of a tissue prior to contacting the tissue with an apparatus for non-invasive optical measurement of the concentration of an analyte. The article ensures that a specific quantity of the coupling agent is deposited in a uniform layer over the entire target area of the tissue, thereby enhancing both the optical signal and the repeatability of thermal and optical coupling with the components of the apparatus. The article comprises a backing and a layer of coupling agent on at least one major surface of the backing.

Abstract: A paper product having an antimicrobial composition dispersed with the substrate is provided. In particular, a paper towel such as those found in public washrooms or institutions comprises an antimicrobial composition. The substrate can also be a facial tissue, kitchen towel, serviette or any type of personal hygiene product. The antimicrobial composition preferably comprises a phenol-derived antimicrobial agent. The paper products of the present invention appear dry to the touch.

Abstract: The present invention provides a nonwoven substrate comprising a fibrous web defining a surface; and a layer of a benefit agent wherein said benefit agent is selected from an additive composition, an enhancement component and combinations thereof; wherein said benefit agent is frothed and bonded to the fibrous web surface through a creping process. Additionally, the present invention provides for a method of creping a nonwoven substrate and also provides for a nonwoven substrate comprising an adhesive film of an aqueous, frothed, benefit agent.

Abstract: This disclosure provides novel compositions comprising an inorganic and organic compound, which provides a means for the indirect attachment of a reactive species, such as an organic reactive molecule, within a binder polymer matrix. Such compositions provide a hydrophilic nanoscale domain that is uniformly dispersed within the polymer matrix. The nanoscale domain comprises inorganic particles having a nanoscale dimension. Such compositions can enhance the performance potential of the re-active species within the polymer material. The polymer composite that results from the introduction of such reactive species into a polymer matrix provides a self-decontaminating feature. The reactive species include those that are capable of associating with a halogen to form a complex that is active in decontamination of chemical or biological agents.

Abstract: Gelatinous foam, coated paper, fabric, and polymer materials combined with the Colloidal Silver or Gold additive to formulate products with anti-microbial surfaces which will then be installed through a process determined by the owner/operator of a multi-person/multi-use facility (with input from the end user) to create anti-microbial areas within the facility. Embodiments of the present invention can be formed from polymer materials with silver or gold additives for creating bacteria-free anti-microbial areas, known as a Clean Zone™, in multi-use or multi-person facilities, such as gyms, hotels, hospitals, doctors' offices, food courts, restaurants, cruise ships, buses, and airplanes. The various embodiments include coated polymer sheets, polymer trays, bamboo and/or cotton towels, rugs and fabric, polymer foam, or polymer mats containing nano-silver or nano-gold in an scheduled and organized manner (with input/requests from the customer) to create permanent or semi-permanent anti-microbial surfaces.

Abstract: The invention relates to a prophylactic article with a carrier element, which comprises at least in part a natural or synthetic elastomer, and with a combination of active substances that is contained in microcapsules, wherein the microcapsules are arranged at least in part in and/or on the carrier element. The combination of active substances contains at least one skin care agent, at least one preservative, at least one odor-inhibiting agent and at least one antioxidant.

Abstract: The present disclosure provides a paper product having at least two plies. Only one outer surface of the tissue paper product has a lotion and a polyhydroxy compound having a molecular weight ranging from about 150 to about 4,000 and selected from the group consisting of glycerols, polyglycerols, polyethylene glycols (PEGs), polyoxyethylenes, polyoxypropylenes, and combinations thereof applied thereto by slot extrusion. The polyhydroxy compound provides the tissue paper product with a Wet Burst greater than about 90 g, a Dynamic Coefficient of Friction less than about 0.9, and a Bending Flexibility less than about 0.042 gf cm2/cm.

Abstract: This invention relates to high surface area materials, such as nanoparticles, that are coated with metal ions. These modified nanoparticles have active sites that bind various gases and/or odorous compounds, thereby removing these compounds from a medium such as air or water. Metal ions are adsorbed onto the surface of the nanoparticle and bound strongly to the surface. By selection of the metal ion, specific gaseous compounds and/or odorous compounds can be targeted and removed efficiently and effectively from both aqueous phase and from the air. The modified nanoparticles are useful in numerous article of manufacture for industrial and consumer use.

Abstract: The present invention relates to the vapor-phase application of at least one spinosyn to treat pests including, for example, vadult mosquitoes and houseflies.

Abstract: Peptides of general formula (I): R1—Wn—Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp—Zs—R2 their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, their preparation process, cosmetic or pharmaceutical compositions which contain them and their use in the treatment and/or care of conditions, disorders and/or diseases that are a consequence of muscle contraction.

Abstract: The present invention describes wet-wipe composition with a liquid portion that is impregnated in a substrate, wherein the liquid portion contains a thickening or gelling polymer along with a thickening or gelling agent which substantially reduces fluid migration of the liquid portion within a wet-wipes stack during storage wherein the thickening or gelling agent is incorporated into the substrate through means of physical entanglement or thermal bonding.

Abstract: The present invention relates to the field of non-woven textile products, and is applied to the manufacture of non-woven fabric products or generally nonwovens for various applications such as household use and personal care. In particular, the present invention relates to a wet nonwoven fabric product impregnated with a substance for personal care, household application or topic medical use, characterised in that the said nonwoven fabric is a bonded web structure with hydrophilic properties or that is made hydrophilic by treatment with wetting additives.

Abstract: The present disclosure encompasses compositions comprising a surfactant, and an acid such as, but not limited to, levulinic acid, that together have a synergistic effect in reducing the viability of a virus population compared to the efficacy of the individual compounds. This synergy allows the formulation of compositions where the active agents (including an acid and a surfactant) are present at concentrations effective to inactivate viruses on surfaces, including human skin. The viricidal compositions disclosed herein are efficacious without damaging the surface to which they may be applied, or even altering the organoleptic properties of a treated food substance. The viricidal compositions and wipes containing such compositions are suitable for sanitizing any surface suspected of having a viral load thereon, or where it is desirable to ensure that a viral load is as low as possible.

Abstract: A multi-component medicament composition for the treatment of scars comprising a combination of a steroid and silicone.

Abstract: A stoma wipe and adhesive remover is for use by an ostomy patient in cleaning a stoma and the area of skin surrounding the stoma, also known as the peristomal skin. The stoma wipe includes a convenient, pre-moistened and disposable towelette. The towelette includes an absorbent fibrous web of material into which is absorbed a liquid cleaning solution having a soap component, an emulsifying component, a water component and an antifungal component. The wipes can be packaged in a convenient, portable, re-sealable package. The stoma wipe is suitable for cleaning a stoma and its surrounding skin area without causing irritation to the stoma and the surrounding skin area, while at the same time removing adhesive residue from an ostomy appliance. The cleaning of the skin and removing old adhesive residue improves adherence of the stoma pouch to the skin area surrounding the stoma.

Abstract: Process for the production of leather using products obtainable by reacting (A) at least one cyclic organic carbonate with (B) at least one compound having at least two nucleophilic groups per molecule, selected from sulfonic acid, hydroxyl, primary or secondary amino or mercapto groups.

Abstract: A method for producing fibers with improved color and anti-microbial properties is described. One embodiment includes a method for generating a halogen stable anti-microbial synthetic fiber, the method comprising creating a mixture that includes a polymer, an anti-microbial agent, and a cationic pigment, and extruding the mixture to form an anti-microbial synthetic fiber.

Abstract: Urea compositions useful for treatment of dermatological conditions. The compositions, which are free from perceptible solids, may include at least about 50 wt-% urea, zinc pyrithione, and lactic acid, and may be formulated as a topical gel.