Antifungal Or Antibacterial Patents (Class 424/404)
  • Patent number: 11872218
    Abstract: Methods and compositions for treating disorders of the nail and nail bed. Such compositions contain a vehicle in which all components of the composition are dissolved, suspended, dispersed, or emulsified, a non-volatile solvent, a wetting agent, and a pharmaceutically active ingredient that is soluble in the non-volatile solvent and/or a mixture of the vehicle and the non-volatile solvent, and which composition is effective in treating a disorder of the nail or nail bed.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: January 16, 2024
    Assignee: BAUSCH HEALTH IRELAND LIMITED
    Inventors: Gareth Winckle, Gregory T. Fieldson
  • Patent number: 11821118
    Abstract: The invention relates to a nonwoven fabric containing at least a portion of individualized bast fibers with a mean length of greater than about 6 mm which have been treated to produce a crimp, and which can be further coated with one or more thermoplastic polymers to ensure compatibility with QAC sanitizers, and which typically having a reduced level of naturally occurring pectin. The coating and crimp of the bast fibers in these nonwoven fabrics is beneficial to forming a drylaid, airlaid or wetlaid nonwoven fabric that has desirable properties related to performance in a variety of nonwoven product applications.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: November 21, 2023
    Assignee: BAST FIBRE TECHNOLOGIES INC.
    Inventor: Jason David Finnis
  • Patent number: 11819526
    Abstract: A strain of Lactobacillus gasseri KBL697 and the use thereof are described. The strain of Lactobacillus gasseri KBL697 (Accession No. KCTC 13520BP) attenuates allergic reactions of cells, significantly improves symptoms of atopic dermatitis, and exhibits anti-inflammatory and anti-fungal effects and a therapeutic effect for intestinal diseases such as irritable bowel syndrome and colitis. Thus, the single strain alone can achieve all the purposes of alleviating allergic diseases and inflammatory diseases and improving intestinal health, thereby finding advantageous applications as a probiotic substance. In addition, the strain, based on the anti-fungal activity thereof, can be advantageously utilized in a skin external preparation against various skin diseases caused by fungi, and in a cosmetic composition and a functional patch for alleviating sensitive skin.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: November 21, 2023
    Assignee: KoBioLabs, Inc.
    Inventors: Woo Ri Ko, June Chul Lee, Hyo In Park, Tae Wook Nam, Gwang Pyo Ko, Woon Ki Kim, Dae Hee Han, In Su Kim, Jin Woo Lee, Hye Jin Kim
  • Patent number: 11486088
    Abstract: An anti-staining fabric includes a base cloth and an anti-staining resin. The anti-staining resin is disposed on the base cloth, in which a method of fabricating the anti-staining resin includes the following steps. A first thermal process is performed to mix a polyol, a cross-linking agent, and a choline to form a first mixture, in which a reaction temperature of the first thermal process is between 90° C. and 120° C. A second thermal process is performed to mix the first mixture and a chain extender to form the anti-staining resin, in which the chain extender includes a first reagent and a second reagent, and a reaction temperature of the second thermal process is between 120° C. and 150° C.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: November 1, 2022
    Assignee: TAIWAN TEXTILE RESEARCH INSTITUTE
    Inventors: Chen-Shou Hsu, Sun-Wen Juan, Chun-Hung Lin
  • Patent number: 11484027
    Abstract: An improved technology for inactivation of viruses, for example the SARS-CoV-2 virus that is causing the Covid-19 pandemic, is described. The technology can include a device that includes a substrate coated in a polymer that is infused with a pathogen inactivating material. In various embodiments, at a given time, a portion of the pathogen inactivating material is exposed to the environment, and the device is configured to periodically or intermittently expose additional pathogen inactivating material to the environment. For example, the polymer can be ablative or sacrificial.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: November 1, 2022
    Assignee: Industrial Polymers and Chemicals, Inc.
    Inventor: Thomas J. Kennedy, III
  • Patent number: 11459698
    Abstract: An antimicrobial coated textile is provided. The antimicrobial coated textile includes a textile substrate including a plurality of textile fibers and a coating. The coating includes 77.5 to 97.45 wt. % silica, 0.05 to 2.5 wt. % titanium dioxide, and 2.5 to 20 wt. % an oxide of a second metal, each based on a total weight of the coating. The second metal is selected from a group including zinc (Zn), selenium (Se), iron (Fe), copper (Cu), and zirconium (Zr), and the coating is disposed on a surface of the textile fibers. A method of preparing the antimicrobial coated textile is also provided.
    Type: Grant
    Filed: April 18, 2022
    Date of Patent: October 4, 2022
    Assignee: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
    Inventor: Chanbasha Basheer
  • Patent number: 11406678
    Abstract: A human oral at least partly enteric formulation comprising one or more jojoba components, for controlling, stimulating or modulating functions for patients suffering from a degenerative disease, or for patients at risk from suffering from a degenerative disease, or for patients under therapeutic treatment of a degenerative disease.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: August 9, 2022
    Inventors: Stefaan Raes, Herman Van Den Driessche
  • Patent number: 11371168
    Abstract: Disclosed is a method for producing an antimicrobial heat-retaining fiber. The method includes spinning a spinning solution onto a fiber-forming resin. The spinning solution includes 1.0 to 6.0% by weight of carbon particles and 0.2 to 2.0% by weight of a metal alkoxide coupling agent. The spinning solution further includes 0.5 to 3.0% by weight of inorganic particles composed of a metal powder, a ceramic powder, or a mixture thereof By using the metal alkoxide coupling agent, the carbon particles and the inorganic particles are dispersed in a resin. Also disclosed is a fiber produced by the method. The fiber is prevented from breakage during spinning and is imparted with heat-retaining and antimicrobial functions due to the presence of the carbon particles and the inorganic particles. Further disclosed is a fabric manufactured using the fiber. The fabric can be prevented from deterioration of wash fastness.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: June 28, 2022
    Assignee: G.CLO INC.
    Inventors: Hyung-jin Son, Jae-hun Jung, Tae-won Son, Chang-mok Son
  • Patent number: 11345869
    Abstract: A hydrate formation promoter and the use thereof in methane storage. The hydrate formation promoter is a mixed aqueous solution including cyclopentane, sodium dodecyl sulfate and water, wherein a volume fraction of the cyclopentane is 5% to 23.4% and a mass fraction of the sodium dodecyl sulfate is 0.01% to 0.08%. The hydrate formation promoter can realize effective and rapid formation of methane hydrate at approximate room temperature (25° C.), and can remain stable at higher temperatures.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: May 31, 2022
    Assignee: GUANGZHOU INSTITUTE OF ENERGY CONVERSION, CHINESE ACADEMY OF SCIENCES
    Inventors: Xiaosen Li, Yisong Yu, Zhaoyang Chen
  • Patent number: 11306208
    Abstract: A product for incorporating ultraviolet radiation protection and antimicrobial protection into a synthetic polymer is disclosed which has a quantity of zinc oxide particles modified with a layer of a reactive group that forms a bond with a quantity of synthetic polymer chips having C—H bonds. A product for incorporating ultraviolet radiation protection and antimicrobial protection into a synthetic polymer prior to forming a synthetic material is also disclosed which has a quantity of synthetic polymer chips and a quantity of zinc oxide particles modified with a layer of a reactive group that forms a bond with the quantity of the synthetic polymer chips.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: April 19, 2022
    Assignee: The Sweet Living Group, LLC
    Inventors: Robert B Kramer, Ronald Kramer, Nicholas Marshall
  • Patent number: 11285183
    Abstract: A strain of Lactobacillus gasseri KBL697 and the use thereof are described. The strain of Lactobacillus gasseri KBL697 (Accession No. KCTC 13520BP) attenuates allergic reactions of cells, significantly improves symptoms of atopic dermatitis, and exhibits anti-inflammatory and anti-fungal effects and a therapeutic effect for intestinal diseases such as irritable bowel syndrome and colitis. Thus, the single strain alone can achieve all the purposes of alleviating allergic diseases and inflammatory diseases and improving intestinal health, thereby finding advantageous applications as a probiotic substance. In addition, the strain, based on the anti-fungal activity thereof, can be advantageously utilized in a skin external preparation against various skin diseases caused by fungi, and in a cosmetic composition and a functional patch for alleviating sensitive skin.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: March 29, 2022
    Assignee: KoBioLabs, Inc.
    Inventors: Woo Ri Ko, June Chul Lee, Hyo In Park, Tae Wook Nam, Gwang Pyo Ko, Woon Ki Kim, Dae Hee Han, In Su Kim, Jin Woo Lee, Hye Jin Kim
  • Patent number: 11219207
    Abstract: Compositions related to polymeric rodenticides, methods of making, and methods of use related to rodenticides comprising polymers are generally described. Rodenticides described in some aspects comprise an active ingredient, an attractant, and a binder. The active ingredient may comprise a polymer, such as polyacrylate, which expands upon exposure to water. The rodenticide composition may contain the active ingredient in an amount of 50-80 wt. % versus the total weight of the composition. The attractant attracts the rodent to the composition, while the binder adheres the composition together. Upon consumption of the rodenticide composition by a rodent, the active ingredient expands in the stomach (e.g., upon exposure to water). The expansion of the active ingredient causes the rodent to feel satiated and not search for water and food, ultimately leading to the death of the rodent, often within two days. Certain embodiments described herein are also related to methods of making such compositions (e.g.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: January 11, 2022
    Assignee: Scientific Pest Solutions, LLC
    Inventors: Robert R. Ferraro, Jr., Eric Spicer
  • Patent number: 11191268
    Abstract: A composition for the eradication or control of arthropods comprising at least one film-forming compound dispersed in a water continuous phase and at least one wetting agent, wherein the film-forming compound does not comprise silicone. Methods of preparing a composition according to the present invention, uses of the composition and a kit of parts for preparing the composition are also disclosed.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: December 7, 2021
    Assignee: J.V. Barrett & Co., Limited
    Inventor: Ian Whelan
  • Patent number: 11154063
    Abstract: A method for production of an additive case having the steps of preparing a zinc oxide concentration from a paste of nanometric zinc oxide that was previously subjected to surface treatment based on silane additives, preparing a silver concentrate starting from a silver paste of nanometric metallic silver, and preparing the additive paste by mixing the zinc oxide concentrate and the silver concentrate and a polymeric carrier with a compatible resin. The polymeric carrier and compatible resin are in a proportion of between 10:90 to 90:10. The steps obtains the additive paste of ZnO/AG° in masterbatch in pellet form.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: October 26, 2021
    Assignee: SERVICIOS ADMINISTRATIVOS PEÑOLES, S.A. DE C.V.
    Inventors: Ricardo Benavides Perez, Jose Gertrudis Bocanegra Rojas, Carlos Sergio Tena Salcido
  • Patent number: 11089781
    Abstract: The present proposals relate to an insecticide or miticide composition which demonstrates low phytotoxicity even at relatively high concentrations combined with highly effective insecticidal and miticidal activity. The composition comprises: a fatty acid/amino acid salt, the fatty acid component comprising: one or more unsaturated fatty acids having from 14 to 22 carbon atoms; and one or more saturated fatty acids having from 8 to 18 carbon atoms; wherein the one or more saturated fatty acids having from 8 to 18 carbon atoms forms at least 15 wt. % of the fatty acid component, and wherein the weight ratio of (unsaturated fatty acids having from 14 to 22 carbon atoms) to (saturated fatty acids having from 8 to 18 carbon atoms) is at least 1. Uses of the compositions and methods of killing insects or mites using the compositions also form part of the proposals.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: August 17, 2021
    Assignee: Naturiol Bangor LTD
    Inventors: Owen Thomas Jones, Mark Long
  • Patent number: 11001712
    Abstract: A product for incorporating ultraviolet radiation protection and antimicrobial protection into a synthetic polymer is disclosed which has a quantity of zinc oxide particles modified with a layer of a reactive group that forms a bond with a quantity of synthetic polymer chips having C—H bonds. A product for incorporating ultraviolet radiation protection and antimicrobial protection into a synthetic polymer prior to forming a synthetic material is also disclosed which has a quantity of synthetic polymer chips and a quantity of zinc oxide particles modified with a layer of a reactive group that forms a bond with the quantity of the synthetic polymer chips.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: May 11, 2021
    Assignee: The Sweet Living Group, LLC
    Inventors: Robert B Kramer, Ronald Kramer, Nicholas Marshall
  • Patent number: 10980906
    Abstract: A germ-reducing pen container including a body having a hollow passageway extending therethrough from an insertion end to a distal end for receiving a pen, the hollow passageway having at least one ultraviolet C light operatively attached thereto, an indicator on an outer surface of the body, and a dispensing mechanism operatively attached at the insertion end for dispensing the pen. A method of reducing germs on a pen, by inserting a pen into a body of a germ-reducing pen container, applying ultraviolet C light to the pen, killing the germs on the pen, indicating that the pen has been cleaned, and dispensing the pen.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: April 20, 2021
    Inventor: Miriah Gilliam-Perkins
  • Patent number: 10966883
    Abstract: An absorbent cores includes absorbent material enclosed a core wrap which comprises a liquid permeable substrate layer. The core contains from about 87% to about 100% of superabsorbent polymer and a tube-shaped swelling chamber having a length to width aspect ratio of less than or equal to about 5:1. The area of the core is at least twice the area of the swelling chamber, and the core contains a water responsive immobilizing agent to immobilize the superabsorbent polymer prior to water insult. The tube-shaped swelling chamber is a portion of the absorbent core containing superabsorbent polymer that is delimited by a plurality of continuous permanent seals that each join together overlapping portions of the core wrap and prevent superabsorbent polymer from moving across the seals.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: April 6, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Bruno Johannes Ehrnsperger, Christine Elisabeth Zipf, Andrea Peri
  • Patent number: 10821085
    Abstract: A wipe containing a fibrous web on which is coated an antimicrobial composition is provided. The composition includes a botanical oil derived from a plant (e.g., thymol, carvacrol, etc.). Because the oil is volatile and tends to evaporate and lose efficacy prior to use, a protein is also employed to enhance the composition's long term stability and antimicrobial efficacy. The protein tends to form a substantially continuous film when coated onto the fibrous web. Because such proteins are typically stiff and brittle, a continuous film would restrict the ability of the fibers to move and bend, reducing web flexibility and drape. Thus, it is typically desired that the antimicrobial composition form a discontinuous coating on the web. In this regard, the present inventors have surprisingly discovered that the addition of an organopolysiloxane can help achieve a discontinuous coating without adversely impacting the ability of the protein to stabilize the oil.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: November 3, 2020
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Jaehong Lee, Vasily A. Topolkaraev, Neil T. Scholl, YoungSook Kim, David W. Koenig, James H. Wang
  • Patent number: 10780194
    Abstract: A medical dressing (30) is disclosed, comprising an adhesive layer (3) having a skin-facing surface (6) to adhere the medical dressing to a dermal surface, wherein said adhesive layer comprises a first chemical compound incorporated within said adhesive layer, and wherein at least a portion of said skin-facing surface comprises a coating (9) comprising a second chemical compound. Also disclosed is a method of manufacturing such a medical dressing.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: September 22, 2020
    Assignee: Mölnlycke Health Care AB
    Inventors: Niclas Flach, Kristina Hamberg, Ulf Johannison, Bengt Söderström
  • Patent number: 10721907
    Abstract: The present invention includes multifunctional compositions, methods and binding systems to provide disinfecting and deodorizing coatings for hard and soft surfaces, inorganic and organic solid surfaces and particulate media and other related substrates, including human and animal skin and skin lesions; to provide neutralizing functions for malodors generated by both human, animal and industrial fluids and solid wastes; and to provide neutralizing and degrading functions for nuisance and noxious chemicals. The present invention provides compositions and methods for producing disinfecting, oxidizing and enzyme-inhibiting fluids enabling preparation of durable, stable biocidal and deodorizing coatings and media which can be widely used for biological agent control, prevention and elimination of odors, and degradation of noxious agents susceptible to chemical oxidation, and which take forms that are inoffensive to users and offer high convenience.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: July 28, 2020
    Assignee: OXISCIENCE, LLC
    Inventors: Zhengbing Cao, Xinbo Sun, Simon Johnston, Jeffrey F. Williams
  • Patent number: 10709808
    Abstract: According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at one least substance including dimethicone and/or at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: July 14, 2020
    Assignee: Medline Industries, Inc.
    Inventors: Min Yao, Daniel B. Love, Amin Setoodeh, Debashish Chakravarthy
  • Patent number: 10646094
    Abstract: A novel wipe set and a novel wiping method in which the wipe set is used are provided. With the wipe set comprising a first wipe impregnated with 50 to 200 mg of a sodium hypochlorite aqueous solution per gram of the wipe, a second wipe impregnated with 30 to 110 mg of a sodium thiosulfate aqueous solution per gram of the wipe, and a third wipe impregnated with 4 to 110 mg of a sodium hydroxide aqueous solution per gram of the wipe as well as by the wiping method in which the wipe set of the present invention is used, an anticancer agent spilled on a working table, for example, can be removed effectively.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: May 12, 2020
    Assignees: MS DREAM CO., LTD., NIPRO CORPORATION
    Inventors: Mika Asano, Takeshi Oguro, Tomonori Imamura, Masaru Fujimura
  • Patent number: 10532309
    Abstract: A filter medium with antimicrobial action and a cabin air filter for filtering air for the interior area of motor vehicles, having at least one first filter layer where pollutants can be retained, and a second filter layer adjacent to the first filter layer is provided. The second filter layer is attached to the on-flow side of the first filter layer and contains antimicrobial agents.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: January 14, 2020
    Assignee: MANN+HUMMEL GmbH
    Inventors: Alexander Piry, Ralf Blum, Ellen Fritz
  • Patent number: 10517300
    Abstract: A biocidal additive formulation comprises a silver containing glass particle, and a combination of at least two metal based compounds. A metal in each of the metal based compounds is selected from the group consisting of silver, copper, zinc, mercury, tin, lead, bismuth, barium, cadmium, chromium, titanium, and a combination thereof. Another biocidal additive formulation comprises a silver containing glass particle, ZnO, and Bi2O3. A glass substrate possessing a durable biocidal property and an article possessing a durable biocidal property are also provided.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: December 31, 2019
    Assignee: Microban Products Company
    Inventor: Alvin Lamar Campbell, Jr.
  • Patent number: 10494528
    Abstract: A product for incorporating ultraviolet radiation protection and antimicrobial protection into a synthetic polymer is disclosed which has a quantity of zinc oxide particles modified with a layer of a reactive group that forms a bond with a quantity of synthetic polymer chips having C—H bonds. A product for incorporating ultraviolet radiation protection and antimicrobial protection into a synthetic polymer prior to forming a synthetic material is also disclosed which has a quantity of synthetic polymer chips and a quantity of zinc oxide particles modified with a layer of a reactive group that forms a bond with the quantity of the synthetic polymer chips.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: December 3, 2019
    Assignee: THE SWEET LIVING GROUP, LLC
    Inventors: Robert B Kramer, Ronald Kramer, Nicholas Marshall
  • Patent number: 10470460
    Abstract: A novel product for mold prevention and treatment is disclosed herein. The product comprises water, one or more anti-mold agents, one or more water-soluble fluoropolymers or other water-soluble polymers with similar properties, and one or more emulsifiers. In some embodiments, the product may further comprise one or more preservatives, one or more stabilizers, one or more binders, one or more fining agents, one or more firming agents, one or more thickeners, and/or one or more clarifying agents. The product may be non-toxic, biodegradable, effective for a long-period of time and against a wide variety of molds, and may also provide other features which render it safe for the environment as compared to other commonly used products in mold prevention and treatment.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: November 12, 2019
    Assignee: Miraculum, Inc.
    Inventors: Britt Ann-Christine Langselius, Freddy Kai Klaffmo
  • Patent number: 10208275
    Abstract: The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide a cleaning benefit and surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellency, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: February 19, 2019
    Assignee: The Clorox Company
    Inventors: David R. Scheuing, William L. Smith, Michael Kinsinger, Jared Heymann
  • Patent number: 10195294
    Abstract: This disclosure relates to a tattoo decal containing bacteria that can be applied to skin and function as both a monitoring sensor and a visual indicator. In particular, a temporary tattoo containing a bacteria composite that may be selected or “programmed” to sense, detect, or otherwise react to a variety of stimuli for use in a variety of applications and industries is disclosed.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: February 5, 2019
    Assignee: LOGICINK CORPORATION
    Inventors: Skylar J E Tibbits, Marcelo Coelho, Tal Danino, Carlos Olguin
  • Patent number: 10137219
    Abstract: An absorbent layer for moderating blood flow from a wound has a non-woven fabric layer of water-insoluble chitosan fibers having a coating of water-absorbent starch on at least one face of the fabric layer. The coating of water-absorbent starch penetrates into the fabric layer from a first surface over the chitosan fibers to a depth of at least 25% of the fabric layer of chitosan fibers. The chitosan fibers have average diameters of from 5 to 30 micrometers. The average weight of starch/chitosan may decrease from the first surface from which the starch has penetrated into the fabric to the depth of at least 50% of the fabric layer. The starch may be modified to include hydrophilic groups into or onto molecular chains of the starch.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: November 27, 2018
    Inventor: James F. Drake
  • Patent number: 10096397
    Abstract: Provided is a method for manufacturing a molded plastic products having copper-based compound particulates. The method includes the steps of: reacting copper sulfate with sulfuric salt, at a molar ratio of 1:1 in an aqueous solution at a temperature of 10˜80° C., thereby synthesizing copper sulfide particulates; forming a sheet comprising the copper sulfide particulates dispersed in a thermoplastic resin.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: October 9, 2018
    Assignee: BS SUPPORT CO., LTD.
    Inventors: Seung Woo Baek, Mun Sun Kim
  • Patent number: 10058542
    Abstract: A method for treating a prokaryotic infection in an animal or human by administering a pharmaceutically acceptable composition, comprising administering a source of silver ions and a benzoisoselenazol derivative, e.g., an ebselen derivative.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: August 28, 2018
    Assignee: Thioredoxin Systems AB
    Inventors: Arne Holmgren, Jun Lu
  • Patent number: 10045966
    Abstract: Embodiments of the presently-disclosed subject matter include activators of HssRS that induce endogenous heme biosynthesis by perturbing central metabolism. These molecules are toxic to fermenting S. aureus, including clinically relevant small colony variants (SCVs). The utility of targeting fermenting bacteria is exemplified by the fact that this compound prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces S. aureus pathogenesis. This small molecule is a powerful tool not only for studying bacterial heme biosynthesis and central metabolism, but also establishes targeting of fermentation as a viable antibacterial strategy.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: August 14, 2018
    Assignee: Vanderbilt University
    Inventors: Eric P. Skaar, Laura Anzaldi Mike, Gary Sulikowski, Alex Waterson, Paul Reid
  • Patent number: 10046093
    Abstract: A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: August 14, 2018
    Assignee: The Spectranetics Corporation
    Inventors: Eugene T. Michal, Daniel J. Lerner, Matthew J. Pollman
  • Patent number: 10040097
    Abstract: A method to prepare a self-decontaminating surface, where that method includes disposing a first coating on a surface, where that first coating comprises an organosilane, and disposing a second coating over the first coating, where the second coating comprises TiO2.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: August 7, 2018
    Assignee: Allied Bioscience, Inc.
    Inventors: Craig Grossman, Mai Ngo, Ronald Wysocki
  • Patent number: 10040952
    Abstract: A method to prepare a self-decontaminating surface, where that method includes disposing a first coating on a surface, where that first coating comprises an organosilane, and disposing a second coating over the first coating, where the second coating comprises TiO2.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: August 7, 2018
    Assignee: ALLIED BIOSCIENCE, INC.
    Inventors: Craig Grossman, Mai Ngo, Ronald Wysocki
  • Patent number: 10028482
    Abstract: The present invention includes multifunctional compositions, methods and binding systems to provide disinfecting and deodorizing coatings for hard and soft surfaces, inorganic and organic solid surfaces and particulate media and other related substrates, including human and animal skin and skin lesions; to provide neutralizing functions for malodors generated by both human, animal and industrial fluids and solid wastes; and to provide neutralizing and degrading functions for nuisance and noxious chemicals. The present invention provides compositions and methods for producing disinfecting, oxidizing and enzyme-inhibiting fluids enabling preparation of durable, stable biocidal and deodorizing coatings and media which can be widely used for biological agent control, prevention and elimination of odors, and degradation of noxious agents susceptible to chemical oxidation, and which take forms that are inoffensive to users and offer high convenience.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: July 24, 2018
    Assignee: OxiScience LLC
    Inventors: Zhengbing Cao, Xinbo Sun, Simon Johnston, Jeffrey F. Williams
  • Patent number: 9975914
    Abstract: A method of enhancing the growth of an animal is provided. The method includes causing the animal to ingest or absorb an effective amount of a preparation obtainable by a process including, bringing a tyrosinate moiety into contact with an Fe(III)-containing substance, optionally wherein the tyrosinate moiety is tyrosine and it is brought into contact with the Fe(III)-containing substance in the presence of a base, or wherein the tyrosinate moiety is a tyrosine salt and it is brought into contact with an Fe(III)-containing substance. Methods for inhibiting, reducing, or preventing biofilm formation or buildup on a surface; the treatment of, inhibition of growth of, and inhibition of colonization by, bacteria, both in biological and non-biological environments; disinfecting surfaces, potentiating the effects of antibiotics and other anti-microbial agents, and increasing the sensitivity of bacteria and other microorganisms, to anti-microbial agents are also provided.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: May 22, 2018
    Assignee: Akeso Biomedical, Inc.
    Inventors: Dlawer Ala'Aldeen, Jafar Mahdavi, Panos Soultanas
  • Patent number: 9953741
    Abstract: Molded plastic products having fine particles of copper-based compound with relatively low price, simple process and good economic feasibility and productivity, and method of manufacturing the products are provided. A chemical structure of the molded plastic products is CuxMy, wherein M is any one selected from groups 15 to 17 of the periodic table, x/y is 0.5-1.5. Also the molded plastic products comprises thermoplastic resin which contains dispersed therein copper-based particles reacts copper sulfate with any one salt, selected from among sulfuric salt, hydrofluoric salt and hydrochloric salt, at a molar ratio of 1:1 in an aqueous solution at a temperature of 10˜80° C.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: April 24, 2018
    Assignee: BS SUPPORT CO., LTD.
    Inventors: Seung Woo Baek, Mun Sun Kim
  • Patent number: 9883839
    Abstract: A radiation imaging apparatus includes a hydrophilized portion provided on at least a portion of an outer surface of the radiation imaging apparatus. The hydrophilized portion contains a hydrophilic polymer and an antibacterial agent. A water contact angle of a surface of the hydrophilized portion is equal to or less than 30°.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: February 6, 2018
    Assignee: FUJIFILM Corporation
    Inventors: Fumito Nariyuki, Haruyasu Nakatsugawa, Takafumi Hironaka, Satoshi Tanaka, Michihiro Shibata, Hideo Nagasaki
  • Patent number: 9877875
    Abstract: A hydrogel formulation is provided for use with a film. The hydrogel formulation includes a medical-grade hydrogel and an antimicrobial substance. This hydrogel formulation may be coated onto one or more surfaces of a medical-grade transparent film suitable for a wound dressing. The antimicrobial material may be a silane quaternary ammonium salt. The silane quaternary ammonium salt may comprise 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride. The 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride may constitute about 72% by weight of the silane quaternary ammonium salt. The medical-grade hydrogel may comprise a colloidal gel in which the particles are dispersed in water. Further, the hydrogel formulation may include about 0.01% to about 60% by weight of the antimicrobial substance. The transparent film may further include a release liner applied over the coated side(s) of the transparent film. The transparent film may comprise polyurethane.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: January 30, 2018
    Assignee: Parasol Medical LLC
    Inventor: Patrick E Eddy
  • Patent number: 9868287
    Abstract: Provided is a method for maintaining an ink jet recording apparatus according to the invention in an ink jet recording apparatus which performs recording using a solvent-based ink composition which includes at least one type of organic solvent selected from a group consisting of an ester-based solvent, a hydrocarbon-based solvent, and an alcohol-based solvent, the method including wiping a nozzle forming member, in which nozzles of a head which discharges the solvent-based ink composition are formed, using an impregnation solution and a wiping member with liquid absorbency, in which the impregnation solution contains at least one type of organic solvent selected from a group consisting of a compound which is represented by General Formula (1) below, esters, and dibasic acid esters, R1—O—(R2—O)n—R3??(1) (in General Formula (1) described above, R1 represents a hydrogen atom, an aryl group, or an alkyl group with 1 to 6 carbon atoms, R2 represents an alkylene group with 2 to 4 carbon atoms, R3 represents an ar
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: January 16, 2018
    Assignee: Seiko Epson Corporation
    Inventors: Jun Ito, Makoto Nagase, Kenichiro Kubota, Naoki Koike, Keiji Iida
  • Patent number: 9868669
    Abstract: A precious metal clay regeneration solution contains water and a liquid paraffin, in which an amount of the liquid paraffin is more than or equal to 0.12 parts by mass and less than or equal to 60 parts by mass with respect to 100 parts by mass of the water. A method for regenerating precious metal clay includes a step of bringing water and a liquid paraffin into contact with a solidified precious metal clay, in which an amount of the liquid paraffin is more than or equal to 0.12 parts by mass and less than or equal to 60 parts by mass with respect to 100 parts by mass of the water.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: January 16, 2018
    Assignee: MITSUBISHI MATERIALS CORPORATION
    Inventors: Yoshifumi Yamamoto, Yasuo Ido, Tsukasa Ikeda
  • Patent number: 9855584
    Abstract: A method to prepare a self-decontaminating surface, where that method includes disposing a first coating on a surface, where that first coating comprises an organosilane, and disposing a second coating over the first coating, where the second coating comprises TiO2.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: January 2, 2018
    Assignee: ALLIED BIOSCIENCE, INC.
    Inventors: Craig Grossman, Mai Ngo, Ronald Wysocki
  • Patent number: 9814240
    Abstract: A biocidal additive formulation comprises a silver containing glass particle, and a combination of at least two metal based compounds. A metal in each of the metal based compounds is selected from the group consisting of silver, copper, zinc, mercury, tin, lead, bismuth, barium, cadmium, chromium, titanium, and a combination thereof. Another biocidal additive formulation comprises a silver containing glass particle, ZnO, and Bi2O3. A glass substrate possessing a durable biocidal property and an article possessing a durable biocidal property are also provided.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: November 14, 2017
    Assignee: Microban Products Company
    Inventor: Alvin Lamar Campbell, Jr.
  • Patent number: 9808435
    Abstract: The present invention is directed to antiviral compositions that provide efficacy against non-envelope viruses such as noroviruses. The antiviral compositions comprise an alkyl 2-hydroxycarboxylic acid and an effective amount of a sulfonated surfactant. The composition may be used as a topical on human skin, as a hand sanitizer or as a hard surface cleaning composition.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: November 7, 2017
    Assignee: Ecolab USA Inc.
    Inventors: Daniel E. Pedersen, Hilina Emiru, Carter Martin Silvernail
  • Patent number: 9695363
    Abstract: Disclosed are the use of fluorine substituted olefins, including tetra- and penta-fluoropropenes, in a variety of applications, including in methods of depositing catalyst on a solid support, methods of sterilizing articles, cleaning methods and compositions, methods of applying medicaments, fire extinguishing/suppression compositions and methods, flavor formulations, fragrance formulations and inflating agents.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 4, 2017
    Assignee: HONEYWELL INTERNATIONAL INC.
    Inventors: Rajiv R. Singh, Hang T. Pham, Ian Shankland
  • Patent number: 9622944
    Abstract: Gel-wipes suitable for use in personal care and household cleansing applications are disclosed, which include a substrate having a first surface, a second surface opposing the first surface and a body disposed between and defined by the first and second surfaces, fibers having an outer surface and an inner core, a polymeric gel distributed throughout the substrate such that a substantial portion of the fibers contain the polymeric gel distributed throughout the inner core of the fibers; and a liquid cleansing composition, wherein the inner core of a substantial portion of the fibers and the polymeric gel are substantially free of the liquid cleansing composition; as well as methods of making the gel-wipe.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: April 18, 2017
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Elizabeth Bruning, Gabriella Marie DeMarco, Euen Thomas Graham Ekman Gunn, Claudia Kaminski, Kevin Lahey, Prithwiraj Maitra, Selina Moses, Delores Santora
  • Patent number: 9603799
    Abstract: A vaccine adjuvant composition comprising: a lipid selected from the group consisting of: dipalmitoyl phosphatidlcholine (DPPC), dipalmitoyl phosphatidylglycerol (DPPG), dioleoyl phosphatidylcholine (DOPC), and cholesterol and containing a positively or negatively charged lipid with associated/entrapped protein antigen.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: March 28, 2017
    Inventors: Aryo Sorayya, Mitra Mosharraf, Rajiv Nayar
  • Patent number: 9585822
    Abstract: A method of improving the appearance of skin, involves topically administering to a subject in need thereof a botanical antioxidant composition having a botanical antioxidant extract blend with: (a) at least one hydroxycinnamic acid, and (b) a camellia sinesis, vitis vinifera, euterpe oleracea, curcuma longa, and/or theobroma cacao extract, wherein the composition is in cream, lotion, solution, serum, anhydrous preparation, emulsion, microemulsion, multiple emulsion, gel, solid stick, ointment, dry powder, spray, or aerosol form.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: March 7, 2017
    Assignee: PCR TECHNOLOGY HOLDINGS, LC
    Inventors: Joseph Abernathy Lewis, II, Joseph C. Dinardo