Abstract: It is in the scope of the invention to disclose a biocidic textiles and fabrics, comprising at least one insoluble proton sink or source (PSS). The textiles and fabrics is provided useful for killing living target cells (LTCs), or otherwise disrupting vital intracellular processes and/or intercellular interactions of the LTC upon contact; the PSS comprising (i) proton source or sink providing a buffering capacity; and (ii) means providing proton conductivity and/or electrical potential; wherein the PSS is effectively disrupting the pH homeostasis and/or electrical balance within the confined volume of the LTC and/or disrupting vital intercellular interactions of the LTCs while efficiently preserving the pH of the LTCs' environment.

Abstract: Hydrophobic polymeric coatings which can be non-covalently applied to solid surfaces such as metals, plastics, glass, polymers, textiles, and other substrates such as fabrics, gauze, bandages, tissues, and other fibers, in the same manner as paint, for example, by brushing, spraying, or dipping, to make the surfaces virucidal and bactericidal, have been developed.

Abstract: The invention features an antimicrobial composition comprising a substance P peptide and methods of inhibiting growth of a microorganism by contacting the microorganism with a substance P peptide. Bacterial and fungal pathogens are inhibited by the substance P compositions.

Abstract: A medical film that is excellent in biocompatibility and bioabsorbability and has an excellent strength in suturing and bonding is provided. A reinforcing material 12 made of a biodegradable polymer is placed in a gelatin solution so as to allow the solution to infiltrate in the reinforcing material 12 and then the gelatin is dried. This allows the gelatin that has infiltrated entirely in an internal part of the reinforcing material 12 to gel, thereby forming a gelatin film 11. Thus, a medical film 1 in which the reinforcing material 12 and the gelatin film 11 are integrated is obtained. The gelatin film 11 preferably is a cross-linked gelatin film.

Abstract: Disclosed is a guided bone regeneration membrane including a novel mechanism that effectively induces a bone reconstruction ability. The mechanism is provided by forming a bi-layered structure of a first nonwoven fabric layer containing a silicon-releasable calcium carbonate and a poly(lactic acid) as principal components and a second nonwoven fabric layer containing a poly(lactic acid) as a principal component; and coating the first nonwoven fabric layer with an apatite. The guided bone regeneration membrane is available by using a nonwoven fabric manufacturing technique through electrospinning and a simulated body fluid soaking technique.

Abstract: A fibrinogen preparation is provided which has an improved solubility, may be prepared within a short time and may be used rapidly in clinical set-up. A solid fibrinogen preparation comprising as a main ingredient fibrinogen and further containing the following components: albumin; a nonionic surfactant; a basic amino acid or a salt thereof; and at least two amino acids or a salt thereof selected from an acidic amino acid or a salt thereof and a neutral amino acid or a salt thereof. The solid fibrinogen composition of the present invention may be held on a medical material to form a supporting material holding fibrinogen. Besides, the supporting material holding fibrinogen may be combined with a component comprising as a main ingredient thrombin to provide a fibrin adhesive.

Abstract: A therapeutic article includes a skin contact layer having a plurality of fibers forming a plurality of point-bearing surfaces configured for wear against a user's skin; a personal care composition disposed proximate the fibers; an external layer attached to the skin contact layer; and an intermediate layer interposed between the skin contact layer and the external layer, the intermediate layer being configured to activate the personal care composition, the external layer being configured to direct the activated personal care composition through the skin contact layer to treat the user.

Abstract: The present invention relates to absorbent articles comprising at least a liquid acquisition layer and an underlying liquid storage layer, said absorbent article comprising lactic acid producing bacteria. The lactic acid producing bacteria are dispersed in a hydrophobic carrier and the article further comprises at least one super-absorbent polymer. At least a part of the total amount of super-absorbent polymer and at least a part of the total amount of the bacteria are present in the liquid storage layer.

Abstract: Described here are wound dressings and kits. The wound dressings include povidone compositions that may be directly applied to wound surfaces or provided on substrates to form a composite material. The povidone compositions contain a povidone polymer, where the povidone polymer itself is capable of healing wounds. The povidone compositions may be in particulate form. In other instances, the povidone compositions are formulated as gels, ointments, pastes, films, or other topically applied compositions. Methods for applying the povidone compositions to treat wounds are also described.

Abstract: The invention relates to an epilatory mixture comprising a fructan, preferably inulin. Furthermore, an epilatory composition is disclosed comprising said epilatory effective mixture. Also a method of use of said epilatory composition of the invention for the removal of unwanted hair from the skin is disclosed, as well as a method of use of said composition for carrying out an epilatory treatment which can be carried out by a professional person as well as by a non-professional person.

Abstract: The present invention concerns a method of agaricidal and microbicidal treatment of textile materials, a Neem oil microcapsule composition specifically for said treatment and a bioactive textile material obtained. More particularly, the present invention concerns the industrial and commercial areas of the treatment of fabrics and like products and is of particular application to textile materials produced from natural fibers such as cotton, feathers or down, or synthetic fibers such as polyester, nylon, acrylic or the like, or mixed fibers such as polyester-cotton. The present invention concerns a method of agaricidal and microbicidal treatment of a textile material, in which microcapsules containing Neem oil are fixed on said textile material.

Abstract: The invention relates to the use of a silicone oil emulsion comprising 0.01-85 wt. % of silicones, particularly polydimethylsiloxanes, 0.01-90 wt. % of hydrophobic emulsifier that has an HLB value ranging from 1 to 7 and/or a hydrophilic emulsifier that has an HLB value ranging from 7 to 14 and/or 0.01-90 wt. % of a mixture of one or more hydrophobic and hydrophilic emulsifiers having an HLB value ranging from 1 to 14, and 0.1-99 wt. % of biocompatible saline solution, for producing a medicament as such or in combination with other medicaments or carrier materials for treating septic infections triggered by bacterial, viral, parasitic, and fungal causative agents or diseases in animals and humans caused by traumas.

Abstract: The invention relates to a pre-packaged, pre-moistened towel, which is customized. The towel is made from a woven cloth material, which can be customized by printing logos, designs or words on the towel. The towel can be either disposable or reusable.

Abstract: The invention relates to a product for the targeted release of active substances, especially detergents and/or cosmetic active substances. The inventive product has a layer structure, one layer being impermeable to the active substance and another layer being permeable to the active substance. The two layers define a compartment between them which contains the active substance and optionally a gas-releasing component. The product is preferably suitable for single use and can be used as a cosmetic agent and/or as a cleaning agent.

Abstract: A delivery system for various functional compounds is disclosed. The delivery system incorporates a composition containing alumina. Various functional materials containing particular moieties may be adsorbed onto the alumina and used as desired. The functional compounds can be, for instance, pharmaceuticals, xenobiotics, anti-microbial agents, anti-viral agents, UV absorbers, odor control agents, fragrances, and the like. In one particular embodiment, for instance, certain dyes can be adsorbed onto the alumina surfaces. Once the dye is adsorbed onto the alumina surface, the resulting particles can be combined with a liquid vehicle for use in any suitable printing process.

Abstract: The present invention provides the use of nanoparticles of a compound of general formula MnXy, where M is (i) a metal selected from the group consisting of Calcium (Ca), Aluminium (Al), Zinc (Zn), Nickel (Ni), Tungsten (W) or Copper (Cu); or (ii) a non-metal selected from the group consisting of Silicon (Si), Boron (B) or Carbon (C); in which n is equal to 1, 2, or 3, and X is (iii) a non-metal selected from the group consisting of Oxygen (O), Nitrogen (N), or Carbon (C); or (iv) an anion selected from the group consisting of phosphate (PO43?), hydrogen phosphate (HPO42?), dihydrogen phosphate (H2PO4?), carbonate (CO3), silicate (SiO42?), sulphate (SO42?), nitrate (NO3?), nitrite (NO2?); in which y is equal to 0, 1, 2, 3 or 4; for use in reducing and/or preventing virus transmission. Articles of protective clothing or filters are provided in which the fibres are coated with said nanoparticles for use in reducing and/or preventing virus transmission.

Abstract: The present invention relates to pre-formed devices for delivering benefit agents to the skin, hair or nails. The devices are patches or masks for cosmetic or therapeutic use and comprise a unilamellar, solid gel sheet having at least one surface at least partially coated with a discrete coating composition comprising at least one benefit agent for the skin, hair or nails. The invention also encompasses methods of producing and using such devices. The coating composition allows more efficient delivery of benefit agents to the skin than previously known devices and/or affords greater formulation flexibility.

Abstract: Disclosed is a composition, which may be melt extrudable, comprising polyvinylpyrrolidone-iodine complex in at least one polymer. Also disclosed is a process for preparing the composition or shaped articles, including films, made therefrom. The composition can be extruded, blown film extruded, or molded into films, fibers, tubing, and shaped articles thermoformed or molded shapes, including containers, usable, for instance, as catheters, in delivery systems for drugs and nutrients, specimen containers, or surgical devices.

Abstract: The invention is a cosmetic or dermatological cloth, comprising a water-insoluble nonwoven material, which is moistened with a cosmetic or dermatological impregnating solution comprising an oil-in-water emulsions having a viscosity of less than 2000 mPa·s and comprising one or more partially neutralized glyceride esters selected from the group consisting of monoglyceride and diglyceride esters of saturated fatty acids with citric acid and one or more fatty alcohols selected from the group consisting of branched and unbranched alkyl alcohols with 12 to 40 carbon atoms.

Abstract: The present invention relates to human metabolism, in particular fat reduction and a cosmetic and pharmaceutical formulation, as well as respective uses in particular together with a dressing material according to the invention.

Abstract: The present invention provides a topical composition for application to the perianal and/or labial areas of the skin which helps prevent viscoelastic fluids, such as menses and feces, from attaching to the skin and aids in the reducing the viscoelastic properties of the fluid so that the fluid can flow into absorbent articles. The composition contains at least one viscoelastant material and at least one an anti-adherent material. the composition may be applied with a wipe, including mitts and gloves, a solid stick composition, an aerosol dispenser, a pump spray, a trigger spray, a squeeze bottle, as a foam, as a cream, as an ointment, as a salve, as a gel, as a wash or as a lotion. In addition, absorbent articles, such as pads or pants, diapers and the like may also be used as a means to transfer the composition to the skin.

Abstract: The invention is directed to a spray-on, multilayer, non-woven fabric system and multilayer topical coverings suitable for reducing or alleviating a discomforting condition of the skin and/or an area underlying the skin when applied thereto, where the fabric system includes a first spray-on composition containing a material suitable for reducing or alleviating a discomforting condition of the skin and/or an area underlying the skin when applied thereto, and a second spray-on composition, different from the first spray-on composition for covering the first composition, which includes fibers, a volatile carrier, and a binding agent, and where the multilayer topical covering includes a first layer formed from the first spray-on composition and a second layer covering the first layer, the second layer formed from the second spray-on composition.

Abstract: A method of joining and/or scaling tissues in a surgical procedure or medical treatment, comprising the steps of: (1) applying a matrix protein, a photoactivatable metal-ligand complex and an electron acceptor to a tissue portion; (2) irradiating said tissue portion to photactivate the photoactivatable metal-ligand complex: thereby initiating a cross-linking reaction of the matrix protein to seal said tissue portion or join said tissue portion to an adjacent tissue portion.

Abstract: Low-shrinkage chitosan films containing sugars and laminates made from the films are provided. The films and laminates can be used to make a variety of finished articles that can be used to provide protection from hazardous chemical and biological agents.

Abstract: The present invention relates to novel formulations comprising lipoic acid and hyaluronic acid and/or the derivatives thereof for use in the repair of chronic ulcers, the regeneration of damaged skin, the prevention of skin aging and, when administered by the systemic route, to treat peripheral neuropathies and intoxications by chemical and/or biological agents.

Abstract: Disclosed is a hand-packing instrument in a mitten shape or a glove shape for caring for skin of the back of the hand. The hand-packing instrument has a mitten shape or a glove shape comprising two sheets overlapped and seamed at their edges, in which the two sheets make a mitten shape having an opening through which a hand can be inserted, a first insertion part for enclosing a thumb and a second insertion part for enclosing the four fingers other than the thumb, and an absorbent attached to the inner surface of one of the sheets.

Abstract: A fabric includes therapeutic members formed thereon, the therapeutic member comprising powder including Ge, GeO3, Al2O3, and P for generating and discharging negative ions; MgO, TiO2, and ZrO for emitting FIR radiant heat; Fe for discharging static electricity; and ceramic for generating FIR energy and blocking harmful UV rays; an adhesive mixed with the powder for fixedly secure the therapeutic member onto the fabric; and a dilution agent mixed with the powder and the adhesive for preventing the therapeutic members from being glued together when the fabric is folded. The fabric is adapted to make, for example, an article of clothing, a head band, or a wrist band.

Abstract: A process for making paper substrates having a soft feel involving: (a) providing a paper substrate; (b) providing an emulsion containing: (i) a polyol poly-12-hydroxystearate; (ii) a wax ester; and (iii) a wax; and (c) impregnating the paper substrate with the emulsion.

Abstract: There is provided a method for controlling environmental allergens in articles including toys, bedding, clothing and the like that tend to collect house dust mite and other allergens. One method involves seeding an article with house dust mites, exposing the article to conditions that promote accelerated growth of house dust mites (10, block 100), washing the article to remove house dust mites (20, block 200), testing the washed article to determine that the level of dust mite remaining in the washed article is below a predetermined level (50, block 200), repeating the washing step a number of times approximating the number of washes the article is expected to undergo during its normal useful lifetime (20, block 200) and finally passing the article through a series of quality control tests (30 and 40 block 300) so that the article may be assured as washable to control its mite and allergen levels without loss of integrity and safety over a plurality of wash cycles.

Abstract: The fabric consists of lycra fibres and microfibres and it has long the fibres a glycoprotein (9) and an exapeptide (10). The woof of this fabric and the active principles given to these two substances (9, 10) prevent and/or give the first cures to the diabetic foot.

Abstract: The present invention relates to the use of a tanning agent in or on filters, in particular natural or synthetic fibrous fabric or foams, for the avoidance of infections, these filters in particular being part of respiratory protection masks or respiratory protection apparatuses.

Abstract: The invention relates to an absorbent article, such as a sanitary towel, a panty liner, a tampon, a diaper or an incontinence pad, which article is intended to be positioned in the crotch area of a wearer and has a surface intended during use to be in contact with skin and/or mucous membranes. The article comprises at least one absorbent body (205) and a carrier (102) containing at least one additive intended to be released from the carrier (102). The carrier (102) comprises a polysiloxane gel.

Abstract: Processes for providing durable antimicrobial surfaces are disclosed that comprise treating a polymer substrate surface with formaldehyde followed by treatment with an antimicrobial peptide. Further embodiments include articles, including medical devices, characterized by a durable antimicrobial surface provided by the processes of the invention.

Abstract: A virucidal disinfectant having broad-range activity includes an acidic phosphorus compound and/or salt thereof, an alcohol, and one or more polyalkylene glycols. The disinfectant, which may also kill bacteria and/or fungi, may be used for the hygienic disinfection of animate and inanimate surfaces. The invention also provides a disinfection method and a product containing a disinfectant.

Abstract: The present invention is directed to a reinforced absorbable multilayered hemostatic wound dressing comprising a first absorbable nonwoven fabric, a second absorbable woven or knitted fabric, thrombin and/or fibrinogen.

Abstract: Soft tissue products with a good rate of absorbency, such as facial and bath tissue, are provided by forming a tissue sheet with a non-fibrous polymeric surface structure and thereafter topically applying a softening composition comprising a polysiloxane, a fatty alkyl derivative and glycerin. The non-fibrous polymeric surface structure is created by applying an additive composition to the surface of a tissue sheet prior to or after drying. The additive composition can be an aqueous dispersion containing an alpha-olefin polymer, an ethylene-carboxylic acid copolymer, or mixtures thereof. The alpha-olefin polymer may comprise an interpolymer of ethylene and octene, while the ethylene-carboxylic acid copolymer may comprise ethylene-acrylic acid copolymer.

Abstract: The present invention is directed to attaching drugs and other functional groups to surfaces of nano-sized diamonds (NDs) to enhance the efficacy of drugs and other substances. The method involved enhancing the efficacy of a drug having an active site by acquiring a plurality of nanodiamond (ND) particles having a plurality of carbon chain surface molecules on its surface. Intermediate amine entities are covalently attached to the surface molecules of the ND particles. These are then replaces with said drug molecules such that the active sites of said drug molecules point away from the ND particle exposing them for enhanced activity and enhanced drug efficacy. The efficacy of antimicrobial drugs are enhanced, however, this may be used with many different types of drugs.

Abstract: An odor control composition that includes a silicon oxide compound and a transition metal in an amount of from about 0.2 wt. % to about 10 wt. % of the odor control composition is provided. The silicon oxide compound is formed from a silicon source and a template (e.g., cyclodextrin template).

Abstract: A pair of panties with a skin-whitening effect comprises a wearing space defined therein, and one or more gel blocks each covered by a release film attached to the panties so as to press close to a groin, a waist, and borders between hips and legs of a user to wear the panties. Thereby, after the release film is torn and the panties are worn by the user, skin-whitening, skin-color-lighting, and wrinkle-softening agents contained in the gel blocks can perform skin-whitening, skin-color-lighting, and wrinkle-softening treatment on the above-mentioned user's body portions, while not disturbing the user's daily life.

Abstract: A medicinal delivery device, system and method for providing medicinal treatment to an area skin. The medicinal delivery device may be configured to be a size and shape suitable to conform to the contours of the body (e.g., the perineum region) and configured to retain the medicant, while allowing transfer of the medicinal properties to the skin. The medicinal delivery system may further comprise a containment structure to contain the medicinal delivery device, hold it in place, provide additional comfort, absorb excess water and/or prevent leakage. The medicinal delivery system may further comprise an activation facilitation device to facilitate preparation of the medicinal delivery device for use.

Abstract: The intermolecular mutual recognition between a disease-state inducing substance (e.g., allergen group, pathogen et cetera) and a living body which functions at the time when such a disease-state inducing substance reaches the living body is inhibited by making use of pectins and nucleic acids.

Abstract: The present disclosure is directed to a system and methods for maintaining or improving hand health and hygiene. More particularly, the system and methods prevent or overcome skin damage caused by frequent hand washing and use of hand sanitizers and/or cleansers. The hand care system comprises an article, such as an elastomeric glove, that has a moisturizing liquid liner composition on the skin-contacting surface of the article that delivers a skin health benefit to the skin, a non-irritating hand cleanser capable of moisturizing the skin, and a moisturizing hand sanitizer.

Abstract: This invention generally relates to use of novel nanomaterials comprised of metals in anti-viral applications. Such nanomaterials, for example, can be produced using a high power, pulsed plasma process, which plasma process, optionally, can be performed on the metal with a precursor (i.e., a gaseous precursor, such as acetylene or methane) when forming the unagglomerated nanomaterials. In embodiments of the invention, the metal is nanosilver. Optionally, the nanomaterials may also comprise carbon, including in the form of carbyne.

Abstract: This invention relates to cholesterol-sequestering agents and methods of using cholesterol-sequestering agents to prevent infection. The compositions of the invention can be used to decontaminate skin and environmental surfaces that are contacted with microorganisms such as envelope viruses.

Abstract: In certain embodiments provided are composition suitable for cleansing or treating the skin, the composition comprising: (i) at least 90% water; (ii) a non-ionic surfactant; (iii) one or more hydrophobic emollients present in a concentration from about 200 parts per million (ppm) to about 4000 ppm, and wherein the composition has a ratio of total surfactant concentration to total hydrophobic emollient concentration that is from about 0.5 to about 2.5. In other embodiments, provided are articles comprising a water-insoluble absorbent substrate and a composition comprising a polyol polyhydroxystearate or a water-soluble glyceryl polyacrylate impregnated therein.

Abstract: The present disclosure generally relates to a formulation. More particularly, the formulation may be applied to skin and/or used in combination with a personal care product to improve absorbance and leakage control of the personal care product, and to promote a more positive feel and comfort through improved skin cleanliness and health.

Abstract: A skin treatment system includes a flexible panel having an outer surface and an inner surface. The flexible panel may be configured to surround at least a portion of a user's appendage. The skin treatment system may also include at least one skin treatment insert having an inner surface and an outer surface. The flexible panel may be further configured to releasably engage the skin treatment insert. The skin treatment insert may be configured to receive a topical skin treatment. The inner surface of the skin treatment insert may be configured to apply the topical skin treatment to at least a portion of a surface of the user's appendage.

Abstract: The present invention is directed generally to a layered polymeric monofilament fiber drug delivery device, where each layer of the device can contain a different polymer, drug, additive, or any combination or mixture thereof. The layered nature of the current monofilament polymeric monofilament device provides the capability to modulate the release of one or more drugs and/or the mechanical properties of the fiber so that drug release and device failure can be separately tuned to provide for the tailored introduction of therapeutically effective drugs or agents to a target tissue. Moreover, the fiber may comprise more than one distinct segments along its length, each segment itself having different combinations and/or numbers of layers thereby providing even greater freedom in the design of the therapeutic delivery device. The invention is also directed to a method of manufacturing such a layered polymeric monofilament fiber drug delivery device, and methods of treatment using such devices.

Abstract: A device, comprising an NO eluting polymer is provided. Said device is furthermore provided with microencapsulated liquid (101), such as water or water containing liquid in micro-capsules (101), which water or water containing liquid after breakage of said micro capsules, initiates elution of NO from said device. Furthermore, a manufacturing method for said device is disclosed.

Abstract: The present disclosure generally relates to methods and compositions for reducing inflammation and/or pain, and more particularly, to compositions comprising an NSAID and oleocanthal and/or a related compound. The compositions are particularly suitable for topical delivery and may be used to relieve the effects of arthritis.