Abstract: Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:13-24, or the nucleotide sequence set forth in SEQ ID NO:1-12 and 25-44, as well as variants and fragments thereof.

Abstract: A method for controlling protozoa trophozites and cysts wherein biocides or control agents are encapsulated within microcapsules or manufactured into the core of liposomes, thereafter the biocide containing microcapsules or liposomes are then introduced into an aqueous system.

Abstract: A composition that generates and releases a biocidal solution comprising at least chlorine dioxide is presented. The composition comprises reactants capable of in-situ generation of chlorine dioxide, and a gelling agent that slows the rate of dissolution of the reactants, thereby increasing yield and providing a controlled release of biocidal solution. The compositions of the invention show improved environmental stability which can reduce the cost of packaging. The controlled release allows the use in multi-tablet chemical dispensers which may otherwise induce potentially explosive conditions or allow rapid release of the biocidal solution thereby inducing a spike in chemical concentration rather than a sustained release.

Abstract: The invention relates to novel microcapsule formulations of (A) a particulate disperse phase of microcapsules comprising (1) a polyurea and/or polyurethane coating with average layer thicknesses of between 5 and 20 nm, and (2) a capsule filling comprising at least one penetrant and, optionally, additives, and (B) a suspension comprising (1) at least one solid agrochemical active compound, (2) additives, (3) water, and (4) optionally, one or more agrochemical active compounds that are liquid at room temperature. The invention further relates to a process for the preparation of these microcapsule formulations and to their use for applying agrochemical active compounds.

Abstract: The present invention refers to a tablet (1) for retaining a volatile substance in a liquid or solid state, such as a perfume and/or an insecticide. The tablet comprises at least a first and a second layers (2,4) of volatile substance retaining material, said first and second layers being spaced apart from each other at a selected distance, and wherein it further comprises a layer of impermeable material (3) joined to said layers and located in between said first and second layers.

Abstract: A structured liquid composition having a liquid matrix having water and a fibrous network structurant, the fibrous network structurant having a non-polymeric crystalline hydroxyl-functional materials; a bacterial cellulose network; and mixtures thereof; and an encapsulated active. The encapsulated active is suspended within the liquid matrix of the structured liquid composition such that the encapsulated actives do not undesirably sink, float, or collect in any discrete portion of the composition. Further, the structured liquid composition can be in the form of a raw material such as an encapsulated active slurry, in the form of an additive such as a laundry additive, and as a consumer end product. In one embodiment, the encapsulated active is a perfume microcapsule.

Abstract: A stable glutaraldehyde polymer complex solution which includes: (a) glutaraldehyde (OCH(CH2)3CHO) in a 0.005% to 45% m/v concentration; (b) a non-ionic surfactant; (c) a buffer; (d) a sufficient amount of a pH modifier to bring the pH of the solution to within a 6.0 to 9.0 range; and (e) a polymer.

Abstract: Process for producing microcapsules comprising an effect-substance-containing capsule core and a polymer-containing capsule covering, comprising the formation of the capsule covering by means of enzyme-catalyzed polymerization of monomers which are present in an inverse miniemulsion; and also microcapsules and dispersions. Use of said microcapsules and dispersions comprising microcapsules as component in colorants, cosmetics, pharmaceuticals, crop protection agents, fertilizers, additives for foods or animal feed, auxiliaries for polymers, paper, textile, leather or detergents and cleaners.

Abstract: The present invention relates to benefit agent containing delivery particles, compositions comprising said particles, and processes for making and using the aforementioned particles and compositions. When employed in compositions, for example, cleaning or fabric care compositions, such particles increase the efficiency of benefit agent delivery, there by allowing reduced amounts of benefit agents to be employed. In addition to allowing the amount of benefit agent to be reduced, such particles allow a broad range of benefit agents to be employed.

Abstract: Disclosed is a powdery pesticidal composition which comprises a mixture of a coated pesticide comprising a powdery pesticide coated with a thermosetting resin and having a volume median diameter of 10 to 150 ?m and a calcium carbonate micropowder having a bulk density of 0.6 g/ml or less, wherein the weight-based ratio of the coated pesticide to the calcium carbonate micropowder is 100:1 to 100:30. The powdery pesticidal composition has good fluidability.

Abstract: The invention relates to a solid oral dosage form comprising a pharmaceutically active ingredient in combination with an enhancer which enhances the bioavailability and/or the absorption of the active ingredient. Accordingly, a solid oral dosage form comprises a drug and an enhancer wherein the enhancer is a medium chain fatty acid ester, ether or salt or a derivative of a medium chain fatty acid, which is, preferably, solid at room temperature and which has a carbon chain length of from 6 to 20 carbon atoms. Preferably, the solid oral dosage form is controlled release dosage form such as a delayed release dosage form.

Abstract: The present invention discloses a nano-cluster that includes a plurality of nano-particles, wherein the nano-particles can disperse in response to an environmental cue. Also disclosed is a method of preventing, treating, or diagnosing a disease or condition in a subject comprising administering a therapeutically effective amount of a composition comprising nano-clusters of the present invention.

Abstract: It is possible to perform microencapsulation of a bioactive substance having a solid form at ordinary temperature in a predetermined wall thickness and particle size without the need of dissolving the solid biologically active substance in any solvent by a method for producing a microcapsule, comprising: heating an aqueous dispersion comprising a dispersion stabilizer, an ionic surfactant, the solid biologically active substance, a polymerization initiator and a radical-polymerizable monomer subjected to ultrasonic irradiation. Therefore, the method enables to design a desired particle readily and it is useful for the microencapsulation.

Abstract: Fatty acid salt particles having a size distribution wherein the particles are from about 1 to about 1,000 microns in diameter, use of the particles in pharmaceutical compositions, as well as methods of making and using the particles and compositions.

Abstract: The invention provides a particulate construct comprising a polyhydroxyalkanoate to serve as microcapsules containing a drug, and serving a slow releasing preparation not associated with a practically unacceptable initial burst release but showing a practically acceptable zero-order release for a certain period and a producing method for such particulate construct, and a slow releasing preparation of a high drug content capable of stably incorporating the drug in the particulate construct such as microcapsules, and a producing method for such preparation.

Abstract: Processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided is a rational method for generating protein variants and the resulting variants.

Abstract: A product comprising microcapsules which themselves comprise (a) a polymeric shell; and (b) a core comprising an agrochemical which has a melting point greater than or equal to 25° C. characterised in that the agrochemical is dispersed as a solid in a hydrophobic material which has a melting point greater than or equal to 25° C. but which does not exhibit a glass transition temperature.

Abstract: Disclosed are a pest control composition, a method of pest control, and a method for preparing a pest control composition. The pest control composition includes diatomaceous earth, a porous granular starch, and a control agent, the control agent generally being an oleaginous material that is film-forming on a water surface. The pest control composition generally is in the form of discrete plural compacted particles. Upon release, for instance, onto a body of water, the control agent will be released from the pest control composition and will form a film over at least a portion of the body of water.

Abstract: The invention provides an immunostimulatory nucleic acid comprising CpG motifs, and methods of use thereof in stimulating immunity.

Abstract: It is an object of the present invention to provide a microcapsule product comprising an active material; said active material encapsulated by a polymeric material to provide a polymer encapsulated material wherein said polymeric material comprises an adjunct crosslinker.

Abstract: A microencapsulated insect growth regulating composition comprising an insect growth regulation active ingredient in a wall formed of polyurethane or polyurea, having an average particle diameter of 1 to 40 ?m, a wall thickness of 0.005 to 0.5 ?m, a ratio of a wall thickness/an average particle diameter of 0.0003 to 0.003, and a volume ratio of microencapsulated particles having a particle diameter of not less than 50 ?m of not more than 20% by volume based on a total volume of microencapsulated particles sufficiently exerts efficacy of the active ingredient, i.e., the insect growth regulation activity.

Abstract: A product comprising microcapsules which themselves comprise (a) a polymeric shell; and (b) a core which comprises (i) a solid agrochemical dispersed in a matrix and (ii) a water-immiscible liquid characterised in that the matrix is distributed non-continuously throughout the water-immiscible liquid.

Abstract: A tablet includes benzoic acid and trichloroisocyanuric acid. The tablet provides free available chlorine in water to maintain an N-halamine-containing polymer biocidal, without rendering the water undrinkable from high chlorine content. The tablet may be used in a water purification device having a cartridge containing an N-halamine polymer to provide safe drinking water.

Abstract: The present invention provides an essentially pure compacted 2,2-Dibromo-3-nitrilopropionamide (DBNPA) in a granular and/or tablet and/or briquette and/or pellet form. The present invention further provides a process for preparing the same essentially pure compacted DBNPA.

Abstract: Novel materials for controlling molluscs, such as snails and slugs, using carbohydrates including celluloses, hemicellulose complexes, and/or lignin, for inducing death in molluscs. The materials are non-toxic, will not contaminate a drinking water supply, will not harm fish, birds or wild life, will not cause any harmful effects if swallowed or absorbed through the skin, will not harm children or pets, and can be safely eaten by domestic animals and livestock that may consume such dead molluscs. The materials may be applied in various formulations at various water contents. The materials do not provide nutrition to the molluscs, and disrupt normal bodily functions resulting in death. An attractant may be included to encourage ingestion by the molluscs.

Abstract: The present invention relates to microencapsulated compositions of isothiazolone derivatives and other water insoluble biocides or antifouling agents. In particular, the present invention relates to microencapsulated 4,5 dichloro 2 n-octyl-3(2H)-isothiazolone(DCOIT), useful in marine antifouling coatings and paints.

Abstract: The present invention relates to compositions and methods for the controlled-release of pest control products into aquatic environments. The compositions comprise one or more pest control products in admixture with one or more water soluble and one or more water insoluble waxes. The compositions of the present invention are particularly useful for treating columns of water in catch basins.

Abstract: The system includes a capsule member made from a material which is dissolvable in the digestive fluids of a predator fish and at a selected rate in water. The capsule contains a material which, following ingestion by a predator fish, results in death of the predator fish. A connecting element secures the capsule to a prey fish at a selected location on the fish, including the mouth of the fish, and then released into an aqueous environment for ingestion by a predator fish.

Abstract: A microcapsule can be produced readily by (a) pulverizing a solid pesticidal compound in terpineol, dihydroterpineol, terpinel acetate, dihydroterpinel acetate or a mixture thereof to form a suspension, (b) mixing the resulting suspension and water to prepare a liquid droplet, and (c) forming a coating film of a resin around the liquid droplet. The microcapsule obtained by such a method contains most of the solid pesticidal compound within the microcapsule.

Abstract: The present invention relates to microencapsulated compositions of isothiazolone derivatives and other water insoluble biocides or antifouling agents. In particular, the present invention relates to microencapsulated 4,5 dichloro 2 n-octyl-3(2H)-isothiazolone(DCOIT), useful in marine antifouling coatings and paints.

Abstract: The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.

Abstract: The present invention deals with an alternative interfacial polymerization process of microencapsulation, microcapsule's produced thereof, microencapsulated agrochemicals, pharmaceuticals, catalysts and phase transfer materials, and formulations thereof, by means of microcapsules and starting materials with much lower toxicological profile than customary microencapsulation materials, and with the participation of acetylene carbamide derivatives in the final structure of the microcapsules' wall.

Abstract: The present invention relates to a semi-rigid gel article which contains an antibacterial agent and can be used for disinfecting and/or cleaning a surface. More particularly, the article comprises water, a gelling agent, an antibacterial agent and wherein the article is capable of disinfecting a surface by contacting the surface with the article, rupturing the article by application of pressure and spreading the article on the surface to deliver the antimicrobial agent. The article is suitable to disinfect and/or clean an inanimate or animate surface with or without water.

Abstract: Agricultural crops are protected from the growth of weeds and other undesirable organisms by the application of hydrogen cyanamide in a granular formulation.

Abstract: A pesticidal composition including a microcapsule in which an oil containing a pesticidal active ingredient and an organic solvent is covered with a wall material made of a thermosetting resin, a sorbitan fatty acid ester, a thickener, and water is provided. The pesticidal composition has elution performance suited for an applied situation without the need of changing the design of the microcapsule itself As the thermosetting resin, a polyurethane resin or a polyurea resin is preferred. As the pesticidal active ingredient, an insect growth regulating active ingredient such as 4-phenoxyphenyl2-(2-pyridyloxy)propyl ether is recited.

Abstract: Disclosed are pharmaceutical compositions suitable for oral administration of bioactive peptides. Particularly, the pharmaceutical compositions comprise peptides formulated as suspensions stabilized with a dispersing agent. The compositions may be encapsulated in capsules for oral administration. The compositions show improved dissolution characteristics, which are believed to make them suitable for use in the treatment of gastrointestinal disorders.

Abstract: This invention relates to microcapsules and processes of microencapsulation of water soluble or water dispersible compounds by reverse-phase microencapsulation, referred to agrochemicals but not as a limiting feature, and how to combine them with other oil soluble or oil dispersible compounds in suitable formulations for agriculture, in a industrially viable process that yields tiny microcapsules (<5-10 ?m, preferably) and very homogeneous distribution of particle size, and overall good performance of the formulation. Further, multiple combinations of this reverse-phase microcapsules are disclosed, being specially notorious the combination with normal-phase microcapsules in order to create a Capsule Mixed Suspension (CX) where an outer oil—or alternatively water—phase contains microcapsules of two types: those with a core of water—and actives dissolved or dispersed therein—and those with a core of oil—and actives dissolved or dispersed therein—.

Abstract: A coated pesticidal granule obtained by aggregating a powdery pesticide with a thermosetting resin is capable of enabling a pesticidal active ingredient to be controlled-released. Further, the controlled-release pesticidal granule can be produced by mixing a powdery pesticide with a first liquid component serving as a raw material for a thermosetting resin, a process of adding a second liquid component serving as a raw material for a thermosetting resin, and then making the first liquid component react with the second liquid component to produce a thermosetting resin.

Abstract: The present invention relates to a novel modified release pharmaceutical composition comprising the coated capsule body, coated or uncoated capsule cap, at least one tablet and granulate comprising active substance.

Abstract: A new, novel and useful disinfection and purification system comprised of organic compounds in synergistic action with selected metal ions and method of manufacture and use. One of the benefits that is derived from this system is the ability to quickly and easily treat a surface, fluid or medium for disinfection of bacteria, fungi, viruses, algae and protozoans, with a non-toxic, non-chlorinated mixture that effectively kills all such organisms in minutes or hours. The disinfection and purification system remains effective for long periods of time maintaining its disinfection capacity making it highly effective for stored or transported mediums such as potable drinking water. The disinfection and purification system may be incorporated with carbon block or membrane filters to disinfect filtered liquids such as water to render it potable.

Abstract: An oxidizing agent comprising a pre-measured amount of stabilized potassium hydrogen peroxymonosulfate and a buffer in a sealed water-soluble pouch, said pouch comprising a hydrolyzed copolymer of vinyl acetate and at least one of acrylic acid, methacrylic acid, maleic acid, itaconic acid, and esters thereof is disclosed.

Abstract: Dry flow, low compact, dust free, soluble granules of phosphoroamidothioates, preferably acephate, are produced by the process of 1) pre-mixing technical grade phosphoroamidothioate with specified adjuvants and other inert ingredients; 2) grinding to produce a ground product having a preferred particle size of 5 microns to 10 microns; 3) post-mixing; 4) granulating; 5) drying; 6) sizing to required length, preferably 1.5 to 3.0 mm; 7) and sieving to remove the fines to get the desired dust free soluble granule.

Abstract: Control of Rodents A particulate mixture for use in the control of rodents which comprises a mixture of a plurality of bait particles and a plurality of non-bait particles, wherein each bait particle comprises matter edible by a rodent and a rodenticide and wherein each non-bait particle comprises matter edible by a rodent and has a flavour different from the flavour of a bait particle and wherein the non-bait particles are distinguished from the bait particles by at least one physical characteristic selected from size, shape, surface texture and internal texture. A non-bait particulate food for rodents as use in the control of rodents, when presented in admixture with bait particles to rodents, to encourage consumption of the bait particles. Such non-bait particulate food comprises dry extruded pellets of cereal meal and dried powdered crustacean.

Abstract: The invention relates to a method for increasing the efficiency of surfactants as well as to a method for suppressing lamellar mesophases in microemulsions. According to the invention, block copolymers having a water-soluble block A and a water-insoluble part B are admixed to the surfactants. The use of these substances as additives can considerably increase the efficiency of the surfactants. Moreover, the addition of the block copolymers suppresses the formation of undesired lamellar mesophases in microemulsions.

Abstract: The invention relates to a coating material for protection against microorganism invasion on surfaces which are exposed to the effects of damp or water. The coating material has either a pH-value of at least 11.0 or is provide with a base material for the coating whereby the pH-value is at least 11. The coating material is characterized in that it contains a biocide which bonds to solid particles in a carrier material and is released in a delayed manner therefrom.

Abstract: A solid composition for forming chlorine dioxide on demand and a sealed biocide article.

Abstract: The invention provides encapsulated, microparticulate active ingredient formulations for the controlled release of active ingredients on skin and skin appendages consisting of encapsulation material as casing and at least one enclosed biologically active ingredient as core, which is characterized in that enzymatically degradable organic hyperbranched polymers containing ester groups are used as encapsulation material.

Abstract: A synergistic insecticidal composition is prepared by combining a Chloronicotynyle compound and an Organophosphorus (OP) compound. The preferred synergistically effective amount of the Chloronicotynyle compounds is an amount preferably ranging from 0.1 to 5% by weight of the composition. The preferred synergistically effective amount of the Organophosphorus (OP) compounds is an amount preferably ranging from 30 to 75% by weight of the composition. The composition also preferably includes 69.9 to 20% by weight of conventional agriculturally acceptable carrier(s) and/or excipient.

Abstract: This invention relates to a pharmaceutical formulation, in the form of a tablet, sachet or powder for suspension dosage form, which comprises dry granulated particles of a non-dihydrate form of azithromycin and, optionally, one or more pharmaceutically acceptable excipients. Preferably, the pharmaceutical formulation is a tablet containing between about 40%, by weight, to about 90%, by weight, non-dihydrate azithromycin. More preferably, the pharmaceutical formulation contains non-dihydrate azithromycin selected from the forms B, D, E, F, G, H, J, M, N, O, P, Q, R, or mixtures thereof. Even more preferably, the invention relates to a pharmaceutical formulation wherein the dosage of azithromycin is 250 mgA, 500 mgA, 600 mgA or 1000 mgA. The present invention further relates to a dry granulated azithromycin particle, comprising a form of azithromycin, selected from forms D, E, F, G, H, J, M, N, O, P, Q, R and mixtures of non-dihydrate forms, and at least one pharmaceutically acceptable excipient.

Abstract: The invention relates to a method for crop protection comprising administering to one or both of the crop and its environment a composition comprising a carrier; and microcapsules having a core material comprising a pesticide encapsulated by a silica shell, wherein the silica shell constitutes up to 10% w/w out of the total weight of the microcapsules, and wherein said administration gives rise to pesticide activity with immediate onset and prolonged effect. The invention further relates to a method for acute treatment of a pest-infested crop.