Abstract: The present invention is a saccharide-bsed matrix and the product resulting therefrom made from a maltodextrin feedstock subjected to conditions which induce flash flow of the maltodextrin so that the matrix possesses a physically- or chemically-altered structure from the feedstock. The present invention also includes a method of producing the matrix and of making products which take advantage of the unique properties of the matrix. Such products include, but are not limited to, unique colloidal-like dispersions and suspensions made from the matrix.

Abstract: A slow-release insect repellent composition comprising an insect repellent, an oleophilic chemical soluble in the insect repellent, and a carbohydrate matrix wherein the combination of the insect repellent and oleophilic chemical is entrapped in the matrix such that the repellent is released from the matrix, a fabric substrate containing the composition and method for preparing the composition.

Abstract: Tubules which contain an active agent in their lumen and compositions containing such microtubules are effective for providing a slow, controlled release of the active agent. Such microtubules are useful in the production of coating compositions for the protection of surfaces coming into contact with water, adhesive resins for the production of laminated wood products, and devices for dispensing pesticides.

Abstract: A method is described for controlling or exterminating moles through the use of a bait composition in the form of a gel, paste, or grease. The composition includes an attractant and an active ingredient capable of killing vertebrate pests. The composition is injected into a mole tunnel through a small diameter nozzle, tube or needle to avoid digging open the tunnel or causing it to collapse.

Abstract: A pesticidal or herbicidal composition in particulate form which comprises composite particles. Each of said particles contains a core of an inert substance having a pesticidal herbicide associated therewith and a coating of an electrically resistive material around the core. The particles may also include a second pesticidal material adhering to the electrically resistive coating. The particles carry an electrostatic charge.

Abstract: Baits useful against diabroticine mature and immature beetles contain (a) an insecticide and (b) a feeding stimulant containing a cucurbitacin in a gelatin binder.

Abstract: The present invention relates to chitin beads having a uniform and fine particle size and comprising microsporidian spores whose principal cell wall substance is chitin; chitosan beads comprising N-deacetylated chitin and having a uniform fine particle size; methods for preparing these beads; carriers comprising these beads; and a method for preparing microsporidian spores.Microsporidian spores are proliferated in insect's bodies or cultured cells to obtain chitin beads having the uniform and fine particle size and whose cell wall substance is mainly composed of chitin. The chitin as the major cell wall substance is subjected to N-deacetylation to give chitosan beads. When the insect is a larva of domesticated silkworm, microsporidian spores are proliferated by orally or percutaneously inoculating the spores into the 2nd instar domesticated silkworm larvae in a concentration of 5.times.10.sup.2 to 5.times.10.sup.

Abstract: The invention relates to small sized particles.These particles comprise at least on the surface thereof a wall composed of a mixture of at least one protein and at least one polysaccharide which are cross-linked, preferably by interfacial cross-linking with a polyfunctional acylating agent which forms at least amide and ester bonds, and optionally anhydride bonds with amine, hydroxyl or carboxyl functions of the protein and of the polysaccharide, and which comprise hydroxamic groups on the surface thereof for chelating metal ions.These particles can be used in cosmetics or in pharmacy notably for the chelation or release of metal ions.

Abstract: The present invention relates to the treatment of conditions associated with neuronal activity. Specifically, the invention is drawn to methods and compositions for administering adenosine to inhibit pain syndromes or epilepsy in a patient.

Abstract: Disclosed are methods for the sterilization of a male mammal wherein a composition comprising a biocompatible polymer, a biocompatible solvent, and a contrast agent is delivered to the vas deferens of the male mammal.

Abstract: A slow-release insect repellent composition comprising an insect repellent, an oleophilic chemical soluble in the insect repellent, and a carbohydrate matrix wherein the combination of the insect repellent and oleophilic chemical is entrapped in the matrix such that the repellent is released from the matrix, a fabric substrate containing the composition and method for preparing the composition.

Abstract: The present invention provides methods and compositions used to increase the pest resistance of living organisms. The invention especially provides adherent granules made of starch that are carriers for pest control agents. Simple and economic methods have been developed to prepare said adherent granules. Compositions and characteristics of the granules are disclosed, including their capability for sustained release of pest control agents.

Abstract: Human myeloperoxidase produced by culturing prokaryotic or eukaryotic cells transformed by a vector for the expression of human myeloperoxidase in said cells.

Abstract: A cosmetic or pharmaceutical, particularly dermatological, composition including an effective amount of laminarin or laminarin-derived oligosaccharides as the active ingredient. It has been discovered that laminarin, oligosaccharides derived therefrom and compositions containing same have stimulating, regenerating, conditioning and energising effects on human dermis fibroblasts and human epidermis keratinocytes. Said composition is useful in cosmetics and pharmacology.

Abstract: The invention provides contaminant-reducing agent delivery compositions that are useful for the control of organic or inorganic contaminants in aquatic or terrestrial environments. The compositions comprise one or more superabsorbent solid organic polymers and at least one contaminant-reducing agent. These superabsorbent polymers act as the primary carriers of one or more contaminant-reducing agents effective for the control of organic or inorganic contaminants in aquatic or terrestrial environments. Contaminant-reducing agents include film-forming agents, microbial agents, nutrient agents, and mixtures thereof. The invention also provides a method to entrap and accumulate organic and inorganic contaminants in one or more superabsorbent polymer compositions containing no contaminant-reducing agent. The invention also provides a method to entrap water in superabsorbent polymers to activate natural and applied microbial and nutrient contaminant-reducing agents in terrestrial environments.

Abstract: A method of encapsulating a pesticide with an ultraviolet protectant comprises the steps of forming a slurry of a pesticide and a lignin-containing material, and spraying a stream of acid and the slurry into contact with one another to precipitate the lignin-containing material onto the pesticide and form a protective coating on the pesticide. The pesticide is preferably a biopesticide, and the lignin-containing material is preferably kraft lignin. The method is easily adapted to industrial processes currently used for pesticide production by simply changing the spray drier from a single nozzle system to a dual spray nozzle and then adding the acid stream to the dual nozzle.

Abstract: The invention concerns a liquid gonadotropin-containing formulation characterised in that the formulation comprises a gonadotropin and stabilising amounts of a polycarboxylic acid or a salt thereof and of a thioether compound. The particular proteins (e.g. LH, TSH, FSH, or HCG) are in admixture with the particular stabilizers in an aqueous solution. The preparations contain a sufficient amount of the polycarboxylic acid or a salt thereof, preferably sodium citrate, and a sufficient amount of the thioether compound, preferably methionine, to stabilize the protein. The preparations preferably also include a nonreducing disaccharide like sucrose, and a non-ionic surfactant.

Abstract: Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms.

Abstract: The present invention is to provide a fibrous material containing an antibacterial antifungal agent consisting of specific metal salt of organic compound effective for both antibacterial and antifungal functions and various articles containing the same fibrous material. The inclusion of the antibacterial antifungal agent consisting of specific metal salt of organic compound in fibrous materials allows production of fibrous materials having extremely high antibacterial antifungal activity. Various articles containing the fibrous materials have found to exhibit excellent antibacterial antifungal effects.

Abstract: Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled. release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials.

Abstract: Insecticidal compositions which have an active content of buprofezin (I) ##STR1## in combination with insect-pathogenic fungi.

Abstract: The present invention relates to an insecticidal coating for a seed comprising one or more binders selected from the group consisting of polymers and copolymers of polyvinyl acetate, methyl cellulose, polyvinyl alcohol, vinylidene chloride, acrylic, cellulose, polyvinylpyrrolidone and polysaccharide and an insecticide and filler wherein the binder forms a matrix for the insecticide and filler resulting in a substantially non-phytotoxic seed coating; methods for producing said coating and the seed treated with the above described coating.Additionally the invention concerns a method of controlling soil-borne insect pests, particularly from the order of Coleoptera, such as Diabrotica spp., comprising applying to a seed an insecticidal coating as described above.

Abstract: Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms.

Abstract: The present invention relates to an insecticidal coating for a seed comprising one or more binders selected from the group consisting of polymers and copolymers of polyvinyl acetate, methyl cellulose, polyvinyl alcohol, vinylidene chloride, acrylic, cellulose, polyvinylpyrrolidone and polysaccharide and an insecticide wherein the binder forms a matrix for the insecticide; methods for producing said coating and the seed treated with the above described coating.Additionally the invention concerns a method of controlling soil-borne insect pests, particularly Diabrotica spp., comprising applying to a seed an insecticidal coating as described above.

Abstract: The present invention provides substantially purified cryptdin peptides having a consensus amino acid sequence:X.sub.1 -C-X.sub.2 -C-R-X.sub.3 -C-X.sub.4 -E-X.sub.5 -C-X.sub.6 -C-C-X.sub.7or having a consensus amino acid sequence:X.sub.1 -L-X.sub.2 -C-Y-C-R-X.sub.3 -C-K-X.sub.4 -E-X.sub.5 -G-T-C-X.sub.6 -C-C-X.sub.7wherein X.sub.1 to X.sub.7 each independently is 0 to 10 amino acids. The invention also provides cryptdin analogs, which are devoid of one or more amino acids N-terminal to the first cysteine. In addition, the invention provides nucleic acid molecules encoding cryptdin peptides. The invention further provides methods for detecting inflammatory pathologies in a subject and for treating an inflammatory pathology in a subject by administering a pharmaceutical composition containing a cryptdin peptide.

Abstract: This invention concerns the delivery of anti-parasitic agents to ruminant animals. More particularly, the invention concerns delivery of such agents in a controlled manner to enable the agent to have maximum effect on the parasite for longer times than is possible with conventional formulations. The composition of the invention comprises a benzimidazole, macrocyclic lactone, organophosphate, salicylanilide/substituted phenol, tetramisole or pyrimidine anti-parasitic agent dispersed in a medium the solubility characteristics of which are such as to ensure that, following oral administration, controlled amounts of the anti-parasitic agent become available to the parasite, either directly or by absorption into the ruminant blood plasma, during passage of the composition through the rumen, the abomasum and the intestine.

Abstract: A drug composition comprising a mucopolysaccharide (also referred in the art as a glycosaminoglycan) and a drug which is scarcely soluble in water but soluble in a water-miscible organic solvent, wherein fine crystals or fine particles of the drug is attached on or between the particles of a mucopolysaccharide, and a process for preparing the same. The drug composition of the present invention exhibits greatly improved solubility and a dissolution rate of the drug, and thus greatly improve the drug's bioavailability.

Abstract: The present invention relates to cosmetic or pharmaceutical compositions containing a preservative-effective amount of hinokitiol-containing microcapsules, the microcapsules comprising a matrix containing collagen and a glycosaminoglycan.

Abstract: The present invention relates to novel pesticides consisting of granules in which the carrier material is semolina and in which the surface of this carrier material carries microorganisms suitable for controlling pests, their preparation and use for controlling pests.

Abstract: A deer repellent formulation and method for warding off a deer from a shrub or plant. The formulation is an admixture of water, eggs, thiram and an adhesive. The formulation can be applied to a support medium such as clay or a length of rope and then associated with the vegetation to be protected.

Abstract: Methods and compositions for treating type I immunoglobin E (IgE)-dependent hypersensitivity by the administration of monophosphoryl lipid A (MLA) or 3-deacylated monophosphoryl lipid A (3D-MLA) are disclosed. MLA or 3D-MLA administered alone or in combination with an allergen to a patient suffering from type I hypersensitivity reduces levels of total or allergen specific IgE and increases levels of IgG antibody in that patient. MLA and 3D-MLA can be administered as part of a desensitization regimen or as a component of a prophylactic vaccine to prevent a type I hypersensitivity reaction.

Abstract: A granular composition comprising a pesticidally active amount of a fungal biological control agent said agent being present in the form of blastospores.

Abstract: Granular pesticide compositions wherein a pesticide material is applied to a granular substrate using a carrier composition which provides improved adhesion of the pesticide to the substrate and abrasion resistance. The carrier composition may also provide controlled release of the pesticide.

Abstract: The present invention is a device for delivering pesticide to pests, comprising (a) an outer layer comprising a porous water-insoluble polymeric; (b) an inner layer in contact with the outer layer, the inner layer comprising a water-soluble feeding stimulant and a carbohydrate which is at least partially gelatinized; and (c) a toxicant which is present on or in the outer layer, the inner layer, or both. The types of pests for which the device may be used to deliver pesticide are any pests which are able to be controlled by the toxicants used in the device and that can be attracted to an object to feed and/or lay eggs, such as the apple maggot fly, the Mediterranean fruit fly, the house fly, the oriental fruit fly, the blueberry fruit fly, the olive fruit fly, the melon fruit fly, and the Mexican fruit fly as well as other flies, beetles, wasps, moths, cockroaches, and any other insect that can be lured to a device for feeding or egg laying.

Abstract: A poisonous bait for controlling soil-inhabiting pests comprising an active compound for controlling a soil-inhabiting pest and, as excipient, an artificial culture medium for mushrooms or the medium obtained after culture of mushrooms.

Abstract: Flowable composites are disclosed which comprise a) microcapsules comprising one or more non-aqueous pesticidally active compositions enclosed in an inert water-soluble wall material; b) a non-aqueous liquid in an amount sufficient to maintain the composite flowable; the non-aqueous pesticidally active composition and the non-aqueous liquid being reactive with each other and the inert water-soluble wall material being insoluble in and impermeable to the non-aqueous liquid and the pesticidally active composition. Also disclosed are composites in which the pesticidally active compositions are internally-reactive in the presence of a non-aqueous liquid or solvent. Processes for production of the composites and their utilization as pesticides are also disclosed.

Abstract: Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms.

Abstract: An effective amount of active/cyclodextrin complex, in the form of particles having particle sizes below about 12 microns, is incorporated into solid consumer product compositions. The complexes provide fast release of the active when they are wetted even when the amount of water available to effect release of the active is limited as in personal use compositions like drugs, foods, and cosmetics where active release is typically effected by body fluids. Preferred actives include perfumes, flavors, and pharmaceutical materials that are used by consumers.

Abstract: Synthetic, functionalized, graft copolymers of polyesters and amino acids are provided. The copolymers are formed in one embodiment by providing a linear polyester-poly(amino acid) copolymer, and reacting the amino acid groups in the linear polymer with an amino acid derivative in a polymerization reaction to form a comb-like, graft copolymer including a polyester-amino acid backbone and polyamino acid side chains extending from the amino acid groups in the backbone. The poly(amino acid) includes functional groups which permit the covalent or ionic attachment of a biological molecule to the graft copolymer. The functionalized graft copolymers can be used in a wide range of biomedical applications including tissue engineering and drug delivery.

Abstract: Insecticide composition, especially a pediculicide, comprising as active agent, rotenone or reduced rotenone. The composition is characterized in that said agent is bound to small polymer spherules. The retonone and/or reduced is preferably at least 90% pure. The composition may be in the form of a suspension, an emulsion, a powder, a paste, a cream or a foam and the like. The novel composition is useful in the treatment of parasites in both humans and animals.

Abstract: The invention relates to the use for control of Homopteran insect pests of a protein which has toxic or antimetabolic effects on them. According to the invention there is provided a transgenic plant comprising a gene coding for a protein which has toxic or antimetabolic effects on Homopteran insect pests, the gene being associated with a promoter which causes the gene to express the protein in the phloem of the plant.

Abstract: Biocidal proteins capable of isolation from seeds have been characterized. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Amaranthus, Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.

Abstract: The method of making a neurotoxic insecticide which comprises:1. Extracting a relatively heat stable, lipophilic, calcium linked, free sufhydryl, proteinaceous extract from casein, in particular the kappa casein thereof, or a casein containing material, such as skim milk, with a low molecular weight alcohol or acetone, and recovering the extract;2. Mixing the extract with one or more membrane transfer agents, such as detergents or solvents, which allow the transfer of the protein extract across normally impermeable insect membranes, whereby the extract demonstrates neurotoxic insecticidal effects.

Abstract: A proteinaceous emulsion and method for making a proteinaceous emulsion comprising a lipophilic phase, an aqueous phase and a protein emulsifier; which is capable of forming a thin film and has the capability of carrying active ingredients contained in either or both the aqueous phase and the lipophilic phase of the emulsion.

Abstract: A solid pesticide composition such as a bait or granule which is made water resistant by coating the solid pesticide with a hydrophobic fatty acid poly ester of sucrose, sorbitol, sorbinose, glycerol and/or raffinose. The coated solid pesticide composition retains its palatability to the target pest.

Abstract: A method for microencapsulating agriculturally active substances such as pesticides to provide improved resistance to environmental degradation, especially ultra-violet light. The method employs as the UV protectant lignosulfonates, such as sulfite lignin or sulfonated lignin, or alternately sulfonated lignite, sulfonated tannins, napthalene sulfonates or other related compounds in combination with a protein such as a high bloom gelatin to form a capsule wall. The capsule wall formed by the interaction of these components is durable and has an ultra-violet protectant as an integral part of its structure.

Abstract: The invention relates to the use of lectins having specific mannose-binding ability and/or derived from Amaryllidaceae or Alliaceae for the control of insect pests. Transgenic plants containing and capable of expressing foreign genes coding for such lectins are also disclosed.

Abstract: A cosmetic composition comprising corneocyte proteins and transglutaminase in a cosmetically acceptable vehicle is provided. Upon application, the ingredients of the cosmetic cross link with the outer layer of skin, hair or nails to form a protective layer on the skin, hair or nails.

Abstract: A particulate controlled-release pesticide composition having a pesticide encapsulated in a polymer matrix of starch-borax-urea and method of preparation and use thereof is provided. The release rates and release duration of the pesticide compositions are controllable by adjusting the urea content in the compositions. The pesticide composition is preparable by admixing starch, pesticide, urea and water together to form a mixture and agitating the same at a temperature sufficient to gelatinize the mixture and to disperse the mixture. Borax is then added to the mixture in an amount effective to convert the mixture into a rubbery mass. The rubbery mass is then comminuted into small particles, in the presence of added starch, and dried.

Abstract: A composite particle timed release pest control agent comprising a dense core particle, a floatation particle, a pesticide, and a composite forming adhesive. The density of the core particle adapts the composite for broadcast application to aqueous and periodically flooded treatment locus and causes the composite to penetrate foliage to contact environmental water. After contact with water at a treatment locus, water causes the adhesive to soften disassembling the composite particle releasing the floatation particle and the pesticide to the surface of the environmental water. At the surface the dissolution rate of the adhesive causes a timed release of the pesticide for action. The composite particle of the invention can be formulated in a quick release formulation that releases the active pest control agent for control in a one to twelve day period or within 0.1 to 72 hours. A long lasting slow release composite can be manufactured that can be used to obtain effective pest control for 10 to 30 days.