Natural Or Synthetic Resin Patents (Class 424/419)
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Patent number: 5858386Abstract: Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms.Type: GrantFiled: September 2, 1997Date of Patent: January 12, 1999Assignee: Lee County Mosquito Control DistrictInventor: Richard Levy
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Patent number: 5849320Abstract: The present invention relates to an insecticidal coating for a seed comprising one or more binders selected from the group consisting of polymers and copolymers of polyvinyl acetate, methyl cellulose, polyvinyl alcohol, vinylidene chloride, acrylic, cellulose, polyvinylpyrrolidone and polysaccharide and an insecticide wherein the binder forms a matrix for the insecticide; methods for producing said coating and the seed treated with the above described coating.Additionally the invention concerns a method of controlling soil-borne insect pests, particularly Diabrotica spp., comprising applying to a seed an insecticidal coating as described above.Type: GrantFiled: June 13, 1996Date of Patent: December 15, 1998Assignee: Novartis CorporationInventors: Kevin M. Turnblad, Yugu Ang Chen
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Patent number: 5817319Abstract: A free-flowing, non-dusting water dispersible granule of an active agricultural chemical having low friability and effective crush strength for delivery to a desired site as a stable suspension in water, without deleterious foaming, which granule includes about 1-25% by weight thereof of a binder which is a copolymer of (a) polyvinylpyrrolidone and (b) a comonomer selected from a C.sub.4 -C.sub.30 alkene and vinyl acetate, and mixtures thereof.Type: GrantFiled: November 18, 1992Date of Patent: October 6, 1998Assignee: ISP Investments Inc.Inventors: Edward Fu, Ratan K. Chaudhuri, Kolazi S. Narayanan
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Patent number: 5795922Abstract: A radiopaque bone cement used to repair bone or other hard tissues is provided. The bone cement is made from combining a composition containing an acrylic powder and a radiopacifier with a corresponding liquid monomer. Prior to being added to the composition, the radiopacifier is microencapsulated with a bone cement compatible material. When combined with the liquid monomer, the bone cement compatible material dissolves releasing the radiopacifier particles into a bone cement matrix. By being microencapsulated, the radiopacifier is prevented from agglomerating in the cement. Instead, the radiopacifier particles become dispersed throughout the bone cement matrix which not only creates a radiopaque cement but also increases the fatigue life of the cement.Type: GrantFiled: June 6, 1995Date of Patent: August 18, 1998Assignee: Clemson UniversityInventors: Hany W. Demian, Shalaby W. Shalaby
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Patent number: 5750130Abstract: Granular pesticide compositions wherein a pesticide material is applied to a granular substrate using a carrier composition which provides improved adhesion of the pesticide to the substrate and abrasion resistance. The carrier composition may also provide controlled release of the pesticide.Type: GrantFiled: August 9, 1996Date of Patent: May 12, 1998Inventors: Paul Ferrell, Alice P. Hudson
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Patent number: 5747055Abstract: An insecticidal and pesticidal complex including an active ingredient combined with an element to insert and diffuse the active ingredient within a vacuum cleaner dust bag. The element is shaped or sized such that it prevents the active ingredient and/or the element from clogging the permeable wall of the dust bag when the vacuum cleaner is in use. The active ingredient mainly includes a mixture of pesticides and insecticides, a growth hormone analogue, and a neutralizing agent.Type: GrantFiled: June 10, 1996Date of Patent: May 5, 1998Inventors: Jean-Claude Attali, Jean-Claude Vuagnoux
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Patent number: 5733561Abstract: An aqueous suspension-type microcapsule insecticide composition which is obtained by emulsifying a hydrophobic admixture of liquid pyrethroid insecticide or a pyrethroid insecticide and a high boiling point solvent, preferably an alkyl ester of phthalic acid in which the alkyl group has 8-13 carbon atoms to form particles of a suitable size in the presence of an anionic water-soluble polymeric surface active agent and polycondensating melamine-formaldehyde or a derivative thereof on the surface of the said emulsified and dispersed particles, and a process for producing the composition. This composition exhibits stable insecticidal activity over a prolonged period with noticeably reduced toxicity to aquatic life.Type: GrantFiled: December 16, 1994Date of Patent: March 31, 1998Assignee: Mitsui Toatsu Chemicals, IncorporatedInventors: Yoshinobu Shimura, Tamotsu Asano, Seiichi Shimono, Takeshi Imakita, Yukio Kiritani, Yuuji Enomoto, Toshio Matsumoto
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Patent number: 5714157Abstract: Rapidly disintegrating water-dispersible granular agricultural compositions comprising by weight based on the total weight of the composition (a) 0.01-80% of one or more active ingredients, (b) 0.004-60% of a base, (c) 5-95% of urea, (d) 1-30% of one or more urea modifiers and (e) optionally one or more additives selected from wetting agents, dispersants, lubricants, anti-caking agents, chemical stabilizers, and inert diluents that are formed by extrusion.Type: GrantFiled: March 20, 1996Date of Patent: February 3, 1998Assignee: E. I. Du Pont de Nemours and CompanyInventors: Lionel Samuel Sandell, Robert David Wysong
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Patent number: 5711956Abstract: A solid formulation which comprises polyvinylpyrrolidone and a pyrethroid insecticide, for example alpha-cypermethrin, is disclosed for use in the treatment of animals, for example cattle. Also disclosed are uses of the solid formulation and methods which use the solid formulation in the treatment of animals.Type: GrantFiled: June 1, 1995Date of Patent: January 27, 1998Assignee: American Cyanamid CompanyInventors: David John Wedlock, Jonathan Mark Woodburn
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Patent number: 5707639Abstract: There is disclosed an insect growth regulator composition comprising (a) an insect growth-regulating active ingredient and, if necessary, another insecticidal active ingredient, (b) an organic substance having a solubility of not greater than 2% in water at 20.degree. C. and a melting point of 35.degree. through 100.degree. C., and (c) a glycol selected from the group having a melting point of 35.degree. through 100.degree. C. and consisting of polyethylene glycol, polyoxyethylene polyoxypropylene glycol, polyoxyethylene polyoxybutylene glycol, and polyoxyethylene polyoxypropylene polyoxybutylene glycol, wherein the weight of the constituent (b) is equal to or greater than 3% based on the total weight, and a sum of the weight of the constituent (b) and the weight of the constituent (c) ranges from 20 to 98% based on the total weight, the constituent (b) and the constituent (c) being molten and then cooled to be solidified in manufacturing process of the insect growth regulator composition.Type: GrantFiled: October 17, 1994Date of Patent: January 13, 1998Assignee: Sumitomo Chemical Company, LimitedInventors: Masao Owaga, Masao Inoue, Toshiro Ohtsubo, Hitoshi Kawada
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Patent number: 5700475Abstract: Flowable composites are disclosed which comprise a) microcapsules comprising one or more non-aqueous pesticidally active compositions enclosed in an inert water-soluble wall material; b) a non-aqueous liquid in an amount sufficient to maintain the composite flowable; the non-aqueous pesticidally active composition and the non-aqueous liquid being reactive with each other and the inert water-soluble wall material being insoluble in and impermeable to the non-aqueous liquid and the pesticidally active composition. Also disclosed are composites in which the pesticidally active compositions are internally-reactive in the presence of a non-aqueous liquid or solvent. Processes for production of the composites and their utilization as pesticides are also disclosed.Type: GrantFiled: December 29, 1995Date of Patent: December 23, 1997Assignee: Monsanto CompanyInventors: Brent D. Massman, Maria L. Miller
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Patent number: 5698212Abstract: The present invention provides a novel antimicrobial polymer composition having superior weatherability and discoloration resistance to those of the prior art.The present invention provides an antimicrobial polymer composition comprising a polymer and an antimicrobial composition having an antimicrobial coat of an aluminosilicate on the surface of silica gel, wherein said aluminosilicate containing antimicrobial metal ions, characterized in that said antimicrobial polymer composition further comprises thiabendazole.Type: GrantFiled: March 12, 1996Date of Patent: December 16, 1997Assignees: Hagiwara Research Corporation, Japan Electronic Materials CorporationInventor: Zenji Hagiwara
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Patent number: 5698210Abstract: Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive agent as a component selected for treating a population of aquatic organisms, at least one carrier component, and at least one coating component for regulating the controlled release rate and release profile of the bioactive agent in water or at least one bioactive agent and one joint-function component that can serve as both a carrier and coating to regulate the controlled release rate and release profile of the bioactive agent in water, with or without optional binder components and/or additional formulation materials. The components are selected to sink or float so that the complexes will permeate and/or remain in any planar or volumetric segment of a water column for a period of time that is sufficient to effectively treat a population of aquatic organisms.Type: GrantFiled: May 2, 1995Date of Patent: December 16, 1997Assignee: Lee County Mosquito Control DistrictInventor: Richard Levy
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Patent number: 5665369Abstract: A process for producing a solid formulation of a crop protection agent which has an exceptionally fast rate of dispersion in water, and the formulation made by this process. This process includes coextruding a crop protection agent and polyvinylpyrrolidone, and subsequently cooling and milling the extrudate. The resulting granules may be pressed into tablets or agglomerated into larger granular masses.Type: GrantFiled: April 5, 1995Date of Patent: September 9, 1997Assignee: American Cyanamid CompanyInventors: David John Wedlock, Gerhard De Lind Van Wijngaarden
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Patent number: 5663213Abstract: A method is disclosed for improving the UV radiation absorption of a composition containing a UV radiation absorbing agent by adding from about 0.1 weight percent to about 50 weight percent of latex particles, based on total weight nonvolatiles. The latex particles contain a void and have a particle size of from about 100 nm to about 380 nm.Type: GrantFiled: August 24, 1995Date of Patent: September 2, 1997Assignee: Rohm and Haas CompanyInventors: Charles Elwood Jones, Rafael Gonzalez Aviles, David Michael Fasano, Martin Vogel
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Patent number: 5651975Abstract: The invention relates to a method of producing granular mixtures which contain herbicides known per se, the activator used being a solid composition in which the activator ingredients are either impregnated into and/or mixed with a carrier material.Type: GrantFiled: February 15, 1996Date of Patent: July 29, 1997Inventors: Pontus Harju-Jeanty, Ari Juppo
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Patent number: 5651978Abstract: An antibacterial composition having a heat-resistant property sufficient for avoiding its decomposition or discoloration at the resin molding temperature comprises; a silver thiosulfate complex salt carried on silica gel particles having an equilibrium water content of 10% or smaller, wherein at least part of the surface of the silica gel particles carrying said silver thiosulfate complex salt is covered with a coating layer composed of silicon dioxide formed by means of hydrolysis of an alkoxysilane.Type: GrantFiled: August 2, 1996Date of Patent: July 29, 1997Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Toshikazu Tomioka, Katsumi Tomita, Hiroaki Oka, Kenji Hoshino, Atsushi Nishino
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Patent number: 5651977Abstract: Disinfecting compositions directed to the prevention of microbial infections are disclosed. The disinfecting compositions comprise a protic acid, a metal chlorite and a gelling agent which, when combined, provide an effective adherent matrix that acts as a disinfectant barrier for preventing transmission and propagation of microbial infections. The gelling agent includes at least 15% polyacrylamide. The compositions of this invention may be used as teat disinfectants, specifically for use in the dairy industry.Type: GrantFiled: December 14, 1994Date of Patent: July 29, 1997Assignee: Alcide CorporationInventor: Robert D. Kross
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Patent number: 5650161Abstract: The present invention relates to novel dry-blended extrudable pesticidal resin composition, extruded pesticidal resin compositions and pelletized pesticidal resin compositions comprising, as the active ingredient, O,O-diethyl S-[[1,1-dimethylethyl)thio]methyl]phosphorodithioate, O,O-diethyl S-(ethylthiomethyl)phosphorodithioate or a pesticidal chemical wherein said technical grade of said pesticidal chemical has a dermal and/or oral LD50, as measured on rats or rabbits of less than 50 mg/kg. The novel compositions of the present invention are characterized by markedly reduced mammalian toxicity and increased pesticide stability and are essentially free of dust. Further, the present invention also relates to a process for preparing the present safened pesticidal resin compositions.Type: GrantFiled: June 5, 1995Date of Patent: July 22, 1997Assignee: American Cyanamid CompanyInventor: Joseph Fredrick Cannelongo
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Patent number: 5645843Abstract: The present invention relates to novel dry-blended extrudable pesticidal resin composition, extruded pesticidal resin compositions and pelletized pesticidal resin compositions comprising, as the active ingredient, O,O-diethyl S-[[1,1-dimethylethyl)thio]-methyl]phosphorodithioate, O,O-diethyl S-(ethylthiomethyl)phosphorodithioate or a pesticidal chemical wherein said technical grade of said pesticidal chemical has a dermal and/or oral LD50, as measured on rats or rabbits of less than 50 mg/kg. The novel compositions of the present invention are characterized by markedly reduced mammalian toxicity and increased pesticide stability and are essentially free of dust. Further, the present invention also relates to a process for preparing the present safened pesticidal resin compositions.Type: GrantFiled: June 5, 1995Date of Patent: July 8, 1997Assignee: American Cyanamid CompanyInventor: Joseph Fredrick Cannelongo
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Patent number: 5643593Abstract: Water dispersible agricultural chemical formulations are disclosed wherein the individual granules are coated with a water-soluble film. The water-soluble film coating on the granules thus significantly reduces any chemical residue on interior surfaces of containers used to package the formulations for transport/handling, while it does not affect dispersibility of granules and providing the end-user with a variety of crop application rates--i.e., since the entire package does not need to be used. In preferred forms, the present invention is embodied in water dispersible agricultural chemical formulations wherein the water-soluble coating is polyvinyl alcohol, sodium silicate or an alkyl cellulose (e.g., methyl cellulose), of which, polyvinyl alcohol is particularly preferred.Type: GrantFiled: September 14, 1995Date of Patent: July 1, 1997Assignee: BASF CorporationInventors: Kenneth E. Fersch, Arthur J. Miner
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Patent number: 5643592Abstract: Finely-divided particulate additives for polymers with a surface coating comprised of a compound selected from the group consisting of esters of difunctional C.sub.6 -C.sub.40 aliphatic and aromatic carboxylic acids and triesters of phosphoric acid.Type: GrantFiled: August 22, 1994Date of Patent: July 1, 1997Assignee: E. I. Du Pont de Nemours and CompanyInventors: Howard Wayne Jacobson, Joseph V. Kurian, Scott Thomas Sackinger, Chandrakant Shantilal Shah
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Patent number: 5631014Abstract: This invention provides an insecticidal and miticidal agent which contains as an effective ingredient an oxazoline derivative represented by the formula ##STR1## wherein, R.sup.1 represents a fluorine atom, a chlorine atom, a C.sub.1 to C.sub.3 alkyl group or a C.sub.1 to C.sub.3 alkoxy group, andR.sup.2 represents a fluorine atom or a chlorine atom.The insecticidal and miticidal agent exhibits an excellent insecticidal and miticidal activity against harmful insects and mites parasitic on useful plants.Type: GrantFiled: June 6, 1995Date of Patent: May 20, 1997Assignee: Yashima Chemical Industry Co., Ltd.Inventors: Tatsuya Ishida, Chiharu Morikawa, Tatsufumi Ikeda, Junji Suzuki, Yasuaki Hariya, Yasuo Kikuchi
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Patent number: 5620696Abstract: A polymeric device and method for the control of insects on animals is disclosed. The device is in the form of an ear tag or other shape which can be attached to an animal using known techniques. A unique polymer/insecticidal formulation is provided by combining an ectoparasiticidal active compound, such as one or more organophosphates, carbamates, pyrethroids and organochlorines, with a polyurethane polymer. The polymer is the reaction product of 4,4'-diphenylmethane diisocyanate, polytetramethylene glycol and 1,4-butanediol. By utilizing the particular polymers described, high loadings of insecticides are possible and the resulting product shows no tendency to exude insecticide during prolonged storage. The product made according to the invention can provide effective control of horn flies on cattle for six months or more utilizing a single ear tag or the like where it would take two tags constructed according to the prior art to achieve comparable results.Type: GrantFiled: August 10, 1994Date of Patent: April 15, 1997Assignee: Fermenta Animal Health CompanyInventors: Rudolf J. Krzewki, Stanley Ackers
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Patent number: 5609879Abstract: A method of treating a population of social insects includes applying topically to the insect a composition comprising a carrier and an active ingredient. The composition provides a coating that adheres to the insect and is groomable and ingestible by other insects to distribute the active ingredient within the population. In accordance with a preferred embodiment, the composition includes sulfluramid as an active ingredient and an air dryable resin as a carrier. A trap for collection of insects controls temperature within the trap to promote recruitment and also drive the insects to a collection area where they may be treated.Type: GrantFiled: March 30, 1995Date of Patent: March 11, 1997Inventor: Timothy G. Myles
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Patent number: 5607684Abstract: Baits useful in the control of insect populations are made by a process that includes the steps of: (a) forming droplets of a homogeneous, substantially water-free mixture comprising: (i) 0.01-99 wt % of a feeding stimulant in the form of a finely divided particulate or liquid; (ii) 0.01-99 wt % of an insecticide; and (iii) a molten, polymeric binder composition that is solid at 25.degree. C. and exhibits a melting point within the range from about 35.degree. C. to about 65.degree. C.; and (b) making particulate baits from the droplets by cooling the droplets to a temperature below the melting point of the mixture. The absence of added water permits the use of active insecticidal ingredients that are generally temperature sensitive to the drying temperatures needed for commercial spray drying operations as well as those sensitive to the presence of water during extended storage and transport periods. The use of the present water-free process avoids hydrolysis of the active insecticide during those periods.Type: GrantFiled: June 5, 1995Date of Patent: March 4, 1997Assignee: Micro Flo CompanyInventors: Chel W. Lew, Kelly S. Johns
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Patent number: 5593883Abstract: The recovery of live ancient bacteria, fungi and other biological material from various sources fossilized in amber or related resins is described. Several ancient bacterial strains have been classified as related to various species of the modern genus Bacillus, for example, based upon their morphological and biochemical characteristics, and enzymatic activity profiles. Although some of the characteristics of the ancient microorganisms correlate well with their modern counterparts, several differences have been observed. In addition, several of the ancient microorganisms described herein exhibit potent antimicrobial activities against modern bacterial and fungal pathogens which attack animals and plants. Various uses for these ancient microorganisms are envisioned, including their use in agriculture, industrial processes, bioremediation, diagnostic and disease treatment.Type: GrantFiled: October 28, 1994Date of Patent: January 14, 1997Assignee: Ambergene CorporationInventors: Raul J. Cano, Monica K. Borucki
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Patent number: 5589390Abstract: A vermin exterminating element contains a culture carrier which includes nonwoven cloth or woven cloth coated or impregnated with medium components for cultivating a microorganism and with a culture solution of a vermin infectious microorganism, wherein the vermin exterminating element is dried after cultivating the vermin infectious microorganism, and the nonwoven cloth or woven cloth has a thickness of 1.8 mm or more and has a base weight of at least 100 g/m.sup.2.Type: GrantFiled: June 7, 1995Date of Patent: December 31, 1996Assignee: Nitto Denko CorporationInventors: Toshio Higuchi, Yasuhiro Fukushima, Kenji Furumori, Kazuhiro Yamamoto, Minoru Ouchi
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Patent number: 5576009Abstract: A process for the preparation of microcapsules, which comprises rapidly stirring an aqueous solution of a precondensate of urea and a dialdehyde in the molar ratio of urea to dialdehyde of 1:1 to 1:2.5, into an acidified aqueous dispersion of a water-immiscible pesticide or a readily volatile water-immiscible solvent.Type: GrantFiled: August 22, 1994Date of Patent: November 19, 1996Assignee: Ciba-Geigy CorporationInventors: Rudolf Nastke, Andreas Leonhardt, Ernst Neuenschwander
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Patent number: 5492696Abstract: Tubules which contain an active agent in their lumen and compositions containing such microtubules are effective for providing a slow, controlled release of the active agent. Such microtubules are useful in the production of coating compositions for the protection of surfaces coming into contact with water, adhesive resins for the production of laminated wood products, and devices for dispensing pesticides.Type: GrantFiled: June 17, 1993Date of Patent: February 20, 1996Assignees: The Government of the United States of America as represented by the Secretary of the Navy, Geo-Centers, Inc.Inventors: Ronald R. Price, Joel M. Schnur, Paul E. Schoen, Mary Testoff, Jacque H. Georger, Jr., Alan Rudolph, Robert F. Brady
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Patent number: 5468738Abstract: A fungicide containing, as an active ingredient, a metal complex of the formula (I),[M{W--Si(OA.sup.1).sub.k A.sub.3-k.sup.2 }.sub.g ]Z.sub.f (I)wherein M, W, A.sup.1, A.sup.2, k, f, g and Z are as defined in the bore formula (I) of claim 1; and use thereof for various fungicidal substances.Type: GrantFiled: September 15, 1993Date of Patent: November 21, 1995Assignee: Tokuyama CorporationInventors: Minahiro Okabayashi, Zhi-ping Bai
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Patent number: 5456916Abstract: The present invention provides a resin molding composition for preventing gnawing damage by the animal, a microcapsule filled with a capsaicine compound, and a process for producing the capsaicine compound and the microcapsule.Type: GrantFiled: February 22, 1994Date of Patent: October 10, 1995Assignee: Nippon Kayaku Kabushiki KaishaInventors: Mitsuo Kurata, Yasuhiro Ichikawa, Mika Toya, Iwao Takahashi, Yoshinobu Okui, Shoichi Kato, Takeshi Nishitani
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Patent number: 5443822Abstract: This invention provides an improved antiperspirant-deodorant cosmetic stick product. An essential aspect of the cosmetic stick product is a content of particulate antiperspirant and alkali metal bicarbonate ingredients, at least one of which has ingredient particle surfaces coated with a hydrophilic organic polymer.Type: GrantFiled: July 12, 1993Date of Patent: August 22, 1995Assignee: Church & Dwight Co., Inc.Inventors: Wendy R. Greczyn, M. Stephen Lajoie, John R. Berschied, Lawrence Kirschner
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Patent number: 5401506Abstract: An insecticidal composition comprising a first composition having an effective amount of at least one species of entomopathogen distributed in a matrix. A second composition selected from vegetable oil, crop oil and partially hydrogenated oil containing mono- and di-glycerides surrounds the first composition and significantly prolongs nematode viability. The matrix is a nematode-containing macrogel or paste of partially hydrogenated oils containing mono- and di-glycerides. The macrogel matrix is selected from a continuous polymer macrogel or microcapsule-containing macrogel. Partially hydrogenated oils containing mono- and di-glycerides, (e.g., Crisco.RTM. shortening), can also be mixed with free nematodes to produce a paste formulation. Trapping nematodes in a Crisco.RTM. matrix formulation along with a water retentive polymer results in increased protection against desiccation and significantly prolongs viability during storage. An insect feeding stimulant, such as raffinose, may also be added to the mix.Type: GrantFiled: August 14, 1992Date of Patent: March 28, 1995Assignee: Temple UniversityInventors: Frank N. Chang, Michael J. Gehret
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Patent number: 5358979Abstract: A microbiocide-containing concentrate for use in thermoplastic polymers as well as in plastisols, is disclosed. The concentrate is primarily solid at ambient conditions and comprises from 1-30 wt% of a microbiocide, a polymer plasticizer and up to 20 wt% of a thermoplastic resin. These concentrates are primarily useful as masterbatch compositions used for incorporation into polymers in order to protect said polymers from fungal or bacterial attack. Along these lines, the present document also discloses processes for incorporating these materials into a polymer or plastisol, and polymers or plastisols made by these processes.Type: GrantFiled: June 22, 1993Date of Patent: October 25, 1994Assignee: Akzo Nobel nvInventors: Nicolaas J. van Hoboken, Roelof van de Worp, Marius C. Verploegh
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Patent number: 5354556Abstract: A controlled release powder containing discrete micro-particles for use in edible, pharmaceutical and other controlled release compositions is disclosed. The micro-particles have an average size in the range of from 0.1 to 125 .mu.m. Each of the micro-particles is in the form of a micromatrix of an active ingredient uniformly distributed in at least one non-toxic polymer. The micro-particles have a predetermined release of active ingredient when the dissolution rate thereof is measured according to the Paddle Method of U.S. Pharmacopoeia XX at 37.degree. C. and 75 r.p.m.Type: GrantFiled: July 9, 1990Date of Patent: October 11, 1994Assignee: Elan Corporation, plcInventors: Randall T. Sparks, Edward J. Geoghegan
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Patent number: 5350679Abstract: A repeat insult microbial test method in which an antimicrobial agent is applied to a porous permeable substrate. The porous permeable substrate is inoculated with microorganisms, and the porous permeable substrate is incubated for a predetermined period of time, at a temperature which is conducive to the flourishment of the microorganisms. The porous permeable substrate is reinoculated and reincubated a predetermined plurality of times and the inoculated porous permeable substrate is incubated for a final period of time between 18-24 hours at the temperature used previously. The porous permeable substrate is then examined, and the growth of microorganisms is determined.Type: GrantFiled: June 14, 1993Date of Patent: September 27, 1994Assignee: Dow Corning CorporationInventor: Carol A. Hess
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Patent number: 5344825Abstract: The invention relates to a novel advantageous oral dosage form for methanediphosphonates, especially the active ingredient disodium pamidronate. A preferred dosage form comprises:a) disodium-3-amino-1-hydroxypropane-1,1-diphosphonate (disodium pamidronate),b) a cationic macroporous ion exchange resin based on a styrene/divinylbenzene copolymer having an exchangeable aminophosphonate group and, where appropriate,c) further pharmaceutically acceptable excipients.The ingredients can be processed to form tablets, dragees, capsules etc.Type: GrantFiled: April 14, 1993Date of Patent: September 6, 1994Assignee: Ciba-Geigy Corp.Inventors: Satish C. Khanna, Jonathan Green
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Patent number: 5342619Abstract: A polymeric device and method for the control of insects on animals is disclosed. The device is in the form of an ear tag or other shape which can be attached to an animal using known techniques. A unique polymer/insecticidal formulation is provided by combining an ectoparasiticidal active compound, preferably an organophosphate, with a polyurethane polymer. The polymer is the reaction product of 4,4'-diphenylmethane diisocyanate, polytetramethylene glycol and 1,4-butanediol. By utilizing the particular polymers described, high loadings of insecticides are possible and the resulting product shows no tendency to exude insecticide during prolonged storage. The product made according to the invention can provide effective control of horn flies on cattle for six months or more utilizing a single ear tag or the like where it would take two tags constructed according to the prior art to achieve comparable results.Type: GrantFiled: March 2, 1993Date of Patent: August 30, 1994Assignee: Fermenta Animal Health CompanyInventors: Rudolf J. Krzewki, Stanley Ackers
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Patent number: 5326573Abstract: In the combating of agricultural and horticultural pests by applying to a locus from which it is desired to exclude such pests a normally liquid active compound and a normally solid active compound, the improvement which comprises applying such active compound in the form of granules comprisinga) carrier granules having a non-absorptive surface,b) at least one liquid active compound and at least one solid active compound,c) at least one adhesive based on polyurethane as a binder, optionally mixed with a further adhesive selected from the group consisting of polyvinyl acetate, polyvinylpyrrolidine, polyvinyl alcohol, vinyl acetate/di-n-butyl maleate copolymers, acrylic acid ester, vinyl acetate/ethylene, vinyl acetate/ethylene/vinyl chloride, vinyl acetate/acrylic acid ester, vinyl acetate/vinyl ester and styrene/acrylic acid ester, andd) optionally an additive.Type: GrantFiled: February 23, 1993Date of Patent: July 5, 1994Assignee: Bayer AktiengesellschaftInventors: Elmar Antfang, Dimitrios Kerimis, Rolf-Jurgen Singer
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Patent number: 5320066Abstract: A mattress or bed for pets is stuffed with material treated with white cedar oil. Preferably the stuffing comprises cedar shavings and conveniently a washable, removable outer cover is provided over an inner mattress. The cedar oil is environmentally safe, reduces pet odor and acts as an insect and pest repellent.Type: GrantFiled: December 8, 1992Date of Patent: June 14, 1994Inventor: Lori E. Gunter
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Patent number: 5300290Abstract: An anti-microbial composition includes particles having an outer surface onto which an anti-microbial agent has been adsorbed. The particles can be used, for example, for coating the bristles of toothbrushes.Type: GrantFiled: February 8, 1993Date of Patent: April 5, 1994Assignee: Gillette Canada, Inc.Inventor: Jean L. Spencer
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Patent number: 5238682Abstract: Insectproofing fibers are disclosed in which the surface of the fibers is coated with a mixture of an organic insectproofing agent, an organic insectproofing agent included in a monomer-trimer type cyclodextrin having an average molecular weight of 3000 or less and an organopolysiloxane, and the interior of the fibers is also impregnated with the mixture. The insectproofing fibers have an insectproofing effect against bugs for a long period of time and the effect is durable.Type: GrantFiled: November 25, 1991Date of Patent: August 24, 1993Assignee: Mitsubishi Rayon Co., Ltd.Inventors: Masanori Akasaka, Yoshirou Sawai, Kunio Iwase, Hideki Moriishi
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Patent number: 5229124Abstract: Solid solutions comprise a water-soluble thermoplastic resin and a microbicide dissolved therein. These solutions may be added to a rigid thermoplastic resin composition to impart biocidal characteristics thereto. If the microbicide is water-insoluble, the solid solutions may be used to prepare stable dispersions of the microbicide. The solutions also provide for slow release of a microbicide or as a vehicle for providing microbicide to an aqueous solution.Type: GrantFiled: September 20, 1991Date of Patent: July 20, 1993Assignee: Morton International, Inc.Inventors: Nuno M. Rei, Lawrence P. Grant, Roger G. Hamel
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Patent number: 5190764Abstract: A sustained release pesticide comprises solid pesticidal particles comprising a solid, pesticidally active ingredient, substantially the whole surface of the pesticidal particles being coated with a hydrophobic substance.Type: GrantFiled: July 28, 1992Date of Patent: March 2, 1993Assignee: Hokko Chemical Industry Co., Ltd.Inventors: Kaoru Chiba, Shinji Yonemura, Tatsuo Noguchi, Takuo Wada, Satoru Moriyama
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Patent number: 5169644Abstract: New combination carrier granulars are disclosed which comprise a granular carrier material having a compact surface and having applied thereto at least one liquid biocidally active compound, at least one solid biocidally active compound, polyvinyl acetate and polyvinyl alcohol. These combination carrier granules exhibit unexpectedly better activity than prior art materials and have unexpectly high abrasion resistance.Type: GrantFiled: March 11, 1991Date of Patent: December 8, 1992Assignee: Bayer AktiengesellschaftInventors: Hans-Heinz Molls, Jorn Schrader, Edmund Krauthausen, Bernhard Homeyer
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Patent number: 5164096Abstract: Biocide treatment of the water system of a papermaking process comprising the steps of encapsulating the biocide as the core of the capsule in a water suspension, in which the shell is degradable at high water dilution, and introducing the microcapsules into the water stream to undergo dilution release.Type: GrantFiled: November 1, 1991Date of Patent: November 17, 1992Assignee: Nalco Chemical CompanyInventor: Maureen B. Nunn
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Patent number: 5153001Abstract: Vitamin E acts to enhance and improve the effect upon oral administration of coronary active vasodilators and/or blood circulation-promoters. The new use and new agents containing vitamin E are described.Type: GrantFiled: January 10, 1991Date of Patent: October 6, 1992Inventor: Roshdy Ismail
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Patent number: 5102662Abstract: A composition which is an unexpanded plastic resinous material having uniformly dispersed and incorporated therein discrete particles of a highly cross-linked macroporous hydrophobic polymer. The polymer has entrapped therein a chemical which is a repellent for insects. The chemical is compatible with the unexpanded plastic resinous material. Also disclosed is an article of manufacture and the article is preferably an outdoor accessory such as an item of lawn furniture. However, any article of manufacture which is desired to release a repellent for the purpose of inhibiting or eradicating the collection and swarming of insects would be appropriate in accordance with the invention, whether such articles are intended for indoor or outdoor use.Type: GrantFiled: December 8, 1989Date of Patent: April 7, 1992Assignee: Dow Corning CorporationInventor: Margarethe J. Gallagher
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Patent number: 5091186Abstract: A transdermal drug delivery system in which drug delivery is biphasic is provided. Drug is delivered at a therapeutically effective rate during an initial, delivery phase, typically of about 10 to 14 hours, followed by a subsequent, secondary phase during which virtually no drug is delivered. Substantially all of the drug initially loaded into the device is delivered within the initial, delivery phase.Type: GrantFiled: August 15, 1989Date of Patent: February 25, 1992Assignee: Cygnus Therapeutic SystemsInventors: Jesus Miranda, Gary W. Cleary