Candy, Candy Coated Or Chewing Gum Patents (Class 424/440)
  • Patent number: 10278408
    Abstract: Disclosed is confectionery having a transparent or translucent hard candy shell and a water-in-oil emulsion centerfill. Also disclosed is a sugar-free liquid edible composition and use in confectionery products.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: May 7, 2019
    Assignee: INTERCONTINENTAL GREAT BRANDS LLC
    Inventors: Hiroshi Segawa, Yoshimitsu Yamakura, Takaya Koseki, Yuzuru Mitsui, Koichi Enomoto
  • Patent number: 10245278
    Abstract: An aqueous, liquid or semi-liquid pharmaceutical or dietary composition, including at least one L-arginine salt on the basis of at least one gram of the salt per dosage unit. Adding the quantity of water necessary to dissolve an arginine salt, maltitol and, optionally, an alcohol or an alcoholate, ensures the removal of the bitterness from the liquid or semi-liquid compositions made from salified arginine. This specific composition allows considerable doses of arginine to be taken directly via oral administration, by drinking, without adding additional water. Also, a food composition containing a dietary composition as defined above.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: April 2, 2019
    Inventor: Philippe Gorny
  • Patent number: 10221257
    Abstract: Provided is a method of forming a polymer, comprising (a) providing a reaction mixture comprising (i) one or more vinyl monomers, (ii) one or more pH-sensitive inhibition systems, (iii) one or more initiators, and (iv) water; (b) establishing conditions in said reaction mixture such that a free radical polymerization of said vinyl monomer occurs at a location, and (c) after steps (a) and (b) and prior to completion of said free radical polymerization, changing the pH of said reaction mixture to increase the rate of generation of said free radical polymerization at the location of said free radical polymerization.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: March 5, 2019
    Assignee: Rohm and Haas Company
    Inventors: John David Finch, Andrew M. Savo
  • Patent number: 10159702
    Abstract: The present invention provides a therapeutic composition comprising a synergistic combination of caffeine, ginkgo biloba, and ?-phenylethylamine (PEA) or its salt. The invention is also directed to oral dosage forms containing said composition, and to a method of treatment of a psychological, psychiatric, behavioral and/or neurodevelopmental disorder comprising the administration of said compositions and dosage forms to a patient in need thereof.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: December 25, 2018
    Assignee: TRINUTRA LTD.
    Inventors: Itschak Lamensdorf, Yoram Sela, Mor Zeilkha
  • Patent number: 10143684
    Abstract: Methods for treating and diagnosing psychiatric affective disorders, e.g., an affective disorder associated with aberrant Sonic Hedgehog (Shh) signaling, by administering to the subject a therapeutically effective amount of an antagonist to Smoothened (Smo), an antagonist to Patched-1 (Ptch-1) and/or an antagonist to Shh.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: December 4, 2018
    Assignees: University of Massachusetts, University of Miami
    Inventors: Edward I. Ginns, Marzena Galdzicka, Janice A. Egeland
  • Patent number: 10085961
    Abstract: The present invention relates to pharmaceutical compositions comprising dimethyl fumarate and a pharmaceutically acceptable agent which inhibits the enzyme catalyzed degradation of dimethyl fumarate.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: October 2, 2018
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Rajamannar Thennati, Shirish Kulkarni, Amol Kulkarni, Vimal Kaneria, Mukesh Sharma
  • Patent number: 10028977
    Abstract: An effervescent chewable dosage form that comprises a pH neutralization agent, an acid, and an effervescent agent. The chewable dosage form can also further comprise simethicone, a sweetener, and a lubricant. The pH neutralization agent can be calcium carbonate, the acid can be citric acid and the effervescent agent can be sodium bicarbonate.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: July 24, 2018
    Assignee: The Procter & Gamble Company
    Inventors: Mark Edward Stella, John Richard Entwisle, Jason William Newlon, Christine Louis Naykki
  • Patent number: 9994860
    Abstract: MPO1 and MPO2 can be regulated for either decreasing or increasing alkaloid levels in plants, in particular in Nicotiana plants. In particular, suppressing or overexpressing one or more of MPO1 and MPO2 may be used to decrease or increase nicotine and nicotinic alkaloid levels in tobacco plants. Suppression or overexpression of one or more of MPO1 and MPO2 may be used in combination with modification of expression of other genes encoding enzymes on the nicotinic alkaloid biosynthetic pathway such as A622, NBB1, PMT, and QPT.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: June 12, 2018
    Assignee: 22nd Century Limited, LLC
    Inventors: Takashi Hashimoto, Akira Kato
  • Patent number: 9931428
    Abstract: The present invention relates to compositions and methods for eye and contact lens care. More particularly, the invention relates to ophthalmic compositions which contain at least one bioflavonoid component for ocular care, preserving ophthalmic solutions and/or disinfecting contact lenses.
    Type: Grant
    Filed: June 13, 2011
    Date of Patent: April 3, 2018
    Assignee: ORALDENT LIMITED
    Inventors: Francesca Crawford, Philip Gunning, Howard Thomas
  • Patent number: 9861563
    Abstract: The invention provides oral care compositions comprising a mixture of tetrabasic zinc halide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: January 9, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: LaTonya Kilpatrick-Liverman, Zhiqiang Liu, Long Pan, Ying Yang, Guofeng Xu, Michael A. Stranick, Zhigang Hao
  • Patent number: 9814757
    Abstract: Controlled studies demonstrate that products and related methods using soy related peptides lower total and LDL cholesterol levels in individuals. In one exemplary embodiment of the present disclosure, a product containing an effective amount of lunasin peptides that lowers cholesterol levels in an individual that consumes the lunasin peptides is provided. In another exemplary embodiment of the present disclosure, a composition containing an effective amount of lunasin peptides or lunasin peptide derivatives and one or more enzyme inhibitors is provided. In a related exemplary embodiment of the present disclosure, a method for lowering or reducing cholesterol levels in an individual is provided where a product containing an effective amount of lunasin peptides to an individual is provided and a claim that the product lowers or reduces cholesterol, total cholesterol, LDL cholesterol or lipid levels in an individual that consumes the composition is made.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: November 14, 2017
    Assignee: SL Technology, Inc.
    Inventor: Alfredo Flores Galvez
  • Patent number: 9763928
    Abstract: The invention provides a multi-layered pharmaceutical composition comprising two or more formulations with varying properties. In some embodiments, the pharmaceutical compositions provide combinations of different organoleptic properties within the same product. In certain embodiment, these combinations allow for a modified release profile of active ingredients as the user enjoys the pharmaceutical composition. The invention further provides methods for making and using the pharmaceutical composition.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: September 19, 2017
    Assignee: Niconovum USA, Inc.
    Inventors: Donna Walker Duggins, John-Paul Mua, Darrell Eugene Holton, Jr., Daniel Verdin Cantrell
  • Patent number: 9744128
    Abstract: An improved method for manufacture of chewing gums containing active ingredient(s) that preserves the efficacy of the active ingredient(s) by avoiding exposure to high heat and extreme cold during milling that can otherwise degrade the active's efficacy. A chewing gum base is used, along with one or more therapeutically-active ingredients, one or more sweeteners (alcohol-based and/or natural), and one or more flavorings and optional flavor modifiers. The method generally comprises heating the gum base in ovens to melt the gum base. Separately, the active ingredient(s), sweeteners and flavorings are combined in a mixer. The melted gum base is added to the mixer and cools to produce a particulate mixture. As mixing continues the mass cools to room temperature and forms granular pieces. The granular pieces are ground into a powder at room temperature, mixed at room temperature with tableting excipients, and tableted. Several variations on the foregoing are also described.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: August 29, 2017
    Assignee: Mastix LLC
    Inventors: Lisa Bachmann, Robert Estey
  • Patent number: 9717733
    Abstract: A composition is provided that includes a microvesicle derived from an edible plant and a therapeutic agent conjugated to the microvesicle. The therapeutic agent can be chemically-linked to a plasma membrane of the microvesicle with a cross-linking agent and the edible plant can be a fruit or a vegetable. Methods for treating an inflammatory disorder or a cancer are further provided and include administering to a subject in need thereof an effective amount of a composition including a microvesicle derived from an edible plant and having a therapeutic agent conjugated to the microvesicle.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: August 1, 2017
    Assignee: University of Louisville Research Foundation, Inc.
    Inventor: Huang-Ge Zhang
  • Patent number: 9648874
    Abstract: The present invention relates to a wipe suitable for multiple re-use comprising a biopolymer matrix composition, said biopolymer matrix comprising from about 0.1% to about 40% of an essential oil, about 30% to about 95% of a biopolymer, and about 1% to about 50% of a carrier fluid wherein a limited amount of said essential oil can be released from said matrix composition when exposed to a liquid solution; and wherein an additional limited amount of said essential oil can be re-released repetitiously thereafter upon re-use with an additional exposure of a liquid solution to said wipe.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: May 16, 2017
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Vasily A. Topolkaraev, Neil T. Scholl, YoungSook Kim, David W. Koenig, JaeHong Lee
  • Patent number: 9561241
    Abstract: The present disclosure relates to dosage forms and methods that enhance the absorption of minocycline in the gastrointestinal tract and thereby enhance bioavailability of the minocycline, and further provides methods of using these dosage forms for the treatment of conditions such as acne.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: February 7, 2017
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Douglas A. Bakan, Waranush Jitpraphai, Steven B. Newhard, Mitchell S. Wortzman
  • Patent number: 9492379
    Abstract: Disclosed is a quickly soluble oral film dosage for masking a nasty taste, in particular, a quickly soluble oral film dosage comprising a stevioside based sweetener and a high potency sweetener in a ratio by weight (w/w) of 1:3 to 3:1, which may efficiently mask a bitter or nasty taste of a medicine and may be quickly dissolved in a mouth without water, thereby improving an aftertaste thereof thus enhancing dosage acceptability of a patient.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: November 15, 2016
    Assignee: CHABIO & DIOSTECH CO., LTD.
    Inventors: Jin-Kyu Park, Won-Suk Yang, Kyoung Tae Jung
  • Patent number: 9433616
    Abstract: The invention provides methods and compositions comprising an anti-cholinergic agent for decreasing saliva production and treating sialorrhea.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: September 6, 2016
    Assignee: NeuroHealing Pharmaceuticals, Inc.
    Inventors: Marcelo Merello, Neal M. Farber, Eyal S. Ron
  • Patent number: 9420806
    Abstract: A chewing gum composition with high pH-release includes an insoluble gum base matrix and a soluble bulk portion, wherein the gum base matrix and the bulk portion is mixed and extruded to form a final chewing gum core, and wherein the gum base matrix is buffered before mixing with the bulk portion. Furthermore, a method of producing a chewing gum core, wherein a gum base matrix and a bulk portion is mixed and extruded to form a final chewing gum core, and wherein the gum base matrix is buffered before mixing with the bulk portion, and the gum base matrix includes a first amount of buffer from 2 to 20 percent by weight of the gum base matrix before mixing with the bulk portion.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: August 23, 2016
    Assignee: Fertin Pharma A/S
    Inventors: Carsten Andersen, Gitte Lorenzen, Nicolai Arent, Bitten Thorengaard, Helle Wittorff
  • Patent number: 9371509
    Abstract: The invention provides a composition containing an aqueous liquid phase, bacterial cells, and an ionic compound dissolved in the liquid phase. The ionic compound is selected from the group consisting of 1-butyl-3-methyl-imidazolium-thiocyanate, 1-butyl-3-methyl-imidazolium-2(2-methoxy-ethoxy)ethylsulfate, 1-methyl-1-[4-(3-methyl-3H-imidazol-1-ium)-but-1-yl]-3H-imidazolium-di(toluylsulfate), and 1-butyl-3-methyl-imidazolium-octylsulfate. The compositions of the invention are advantageously used for preparing lysates of biological cells, particularly bacterial cells.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: June 21, 2016
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christian Birkner, Herbert von der Eltz, Monika Soukupova
  • Patent number: 9320710
    Abstract: Compositions, systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject for treatment of pain using a device are disclosed.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: April 26, 2016
    Assignee: AcelRX Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine
  • Patent number: 9314230
    Abstract: An anchor for use with a closure device includes a body being configured to move from a pre-deployed state to a deployed state. In the pre-deployed state, the body has a first width aspect relative to a direction of deployment and a second width aspect in the deployed state relative to the direction of deployment, the second width aspect being greater than the first width aspect and the body being formed from a rapidly eroding material configured to erode through dissolution within a body lumen.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: April 19, 2016
    Assignee: ABBOTT VASCULAR INC.
    Inventors: Wouter E. Roorda, Laveille K. Voss, Kelly J. McCrystle, Karim S. Osman
  • Patent number: 9301982
    Abstract: The present application relates to probiotic confection-based compositions comprising lactic acid-producing bacteria and oil-based compositions comprising the same.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: April 5, 2016
    Assignee: Ganeden Biotech, Inc.
    Inventor: Andrew R. Lefkowitz
  • Patent number: 9265753
    Abstract: A diffusion rate limiting matrix is utilized to lingually and/or sublingually deliver thioctic acid. This limited release matrix is intended for general nutritional supplementation and/or the treatment of various physiological disorders. Due to its lingual nature, this rate limiting matrix can produce IV-equivalent plasma levels and is not meant to be swallowed.
    Type: Grant
    Filed: August 31, 2012
    Date of Patent: February 23, 2016
    Inventors: Jeffery Lee Benjamin, Jr., William Carlton Zolentroff
  • Patent number: 9220673
    Abstract: Calcium phosphate particles are described comprising a surface treatment wherein the surface treatment comprises at least one sugar alcohol. Also described are various oral care compositions comprising surface treated calcium phosphate particles and methods of surface treating calcium phosphate particles.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: December 29, 2015
    Assignee: 3M Innovative Properties Company
    Inventors: Richard P. Rusin, Neeraj Sharma, Sumita B. Mitra
  • Patent number: 9167831
    Abstract: An edible, solid composition comprising a laxative and one or more bulking agents in aqueous media wherein the laxative is polyethylene glycol and the composition is prepared by dissolving the polyethylene glycol in aqueous media together with one or more bulking agents and subjecting the mixture to heat up to at least about 100° C.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: October 27, 2015
    Assignee: Gavis Pharmaceuticals, LLC
    Inventors: Veerappan Sellappan Subramanian, Paranjothy Kanni
  • Patent number: 9095734
    Abstract: A molecule for stabilizing a bioactive chemical group capable of releasing nitric oxide in vivo is described. The molecule possesses multi-functionality, enabling the delivery of multiple nitric oxide precursors on a single molecule. In some embodiments, a tissue or prosthetic bonding group is attached to one of the functional arms of the molecule making the molecule of the present invention localizing to tissue or an implant.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 4, 2015
    Assignee: Maple Ridge Group, LLC
    Inventors: Michael Milbocker, Kenneth Rothaus
  • Patent number: 9028882
    Abstract: A nutriceutical food product includes a solid polymeric matrix and a liquid combined into a gel. The nutriceutical food product may include an immune modulator, such as transfer factor and/or a nanofraction immune modulator. A fruit component may be included in the nutriceutical food product. The fruit component may include at least one oligoproanthocyanidin-containing fruit, such as açai.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: May 12, 2015
    Assignee: 4Life Patents, LLC
    Inventors: Brent M. Vaughan, Calvin W. McCausland, David A. Lisonbee
  • Patent number: 9023381
    Abstract: Pharmacologically effective amounts of a medication are delivered in pleasant tasting delivery vehicles, including gelatins and candies. Mechanisms for the reduction in surface area of noxious taste-imparting aspects of conventional medicines, and dilutive effects of positive masking elements for such medicines, especially products for inducing children to take medicines, are taught—in combination with processes and products thereby.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: May 5, 2015
    Inventor: Michelle Chow
  • Patent number: 8968769
    Abstract: The present invention features an orally disintegrating dosage form including from about 5% to about 40%, by weight, of at least one hydrated salt and a pharmaceutically active agent, wherein the at least one hydrated salt has a dehydration temperature of from about 20 to about 120 ° C.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: March 3, 2015
    Assignee: McNeil-PPC, Inc.
    Inventors: Frank Bunick, Joseph Luber
  • Patent number: 8968770
    Abstract: A multi-part kit for administering at least one active pharmaceutical ingredient including at least one piece of chewing gum including the active pharmaceutical ingredient, the piece of chewing gum comprising gum base; and at least one further flavor-containing formulation; wherein the gum base content of the at least one further flavor-containing formulation is less than 70% by weight of the gum base content of said piece of chewing gum.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: March 3, 2015
    Assignee: Fertin Pharma A/S
    Inventors: Kurt Møller Pedersen, Jette Bæk Andersen
  • Publication number: 20150030646
    Abstract: An edible product and method for making an edible product including a core composition having at least one outer surface and at least one edible, three dimensional object secured to the at least one outer surface, where the object includes a binder material and a deliverable component selected from the group consisting of flavors, colors, sweeteners, actives, sensates, effervescent components, and combinations thereof. Also, a method for delivery of at least one deliverable component including placing such products in the mouth of a user and releasing the deliverable component from the edible, three dimensional object.
    Type: Application
    Filed: February 6, 2013
    Publication date: January 29, 2015
    Inventors: Petros Gebreselassie, Atsushi Ueminami, Anilkumar Ganapati Gaonkar
  • Patent number: 8865204
    Abstract: The present invention features a process for making a lozenge product including the steps of forming a powder blend containing an amorphous carbohydrate polymer into the desired shape of the lozenge product and applying radiofrequency energy to the shape for a sufficient period of time to soften or melt said amorphous carbohydrate polymer to fuse the shape into said lozenge product.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: October 21, 2014
    Assignee: McNeil-PPC, Inc.
    Inventors: Jen-Chi Chen, Harry S. Sowden, Joseph R. Luber, Leo B. Kriksunov, Frank J. Bunick, Christopher E. Szymczak, Gregory E. Koll
  • Patent number: 8865133
    Abstract: A bi-layer, oral adhering tablet (troche) made by pressing powders with a bi-layer tablet press, having greater than 80% acacia gum as an adhesive in an adhering layer. In a preferred embodiment, the tablet has about 99% acacia gum.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: October 21, 2014
    Assignee: OraHealth Corporation
    Inventors: Jeffrey T Haley, Steven Edwards
  • Patent number: 8858984
    Abstract: A lozenge is provided that has stable pH and stable levels of active ingredient over time. It comprises a combination of (i) at least one gum and (ii) at least one non-crystallizing sugar or non-crystallizing sugar alcohol in a matrix designed for controlled buccal delivery of a drug. The lozenge also contains water and optional components selected from flavorings, taste masking agents, colorings, buffer components, pH adjusting agents, excipients, stabilizers and sweeteners. Methods of preparing the lozenge are also provided.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: October 14, 2014
    Assignee: Gelmedic Holding ApS
    Inventors: Anders Dam, Janos Major, Peter Tasko
  • Patent number: 8858918
    Abstract: A composition in the form of a chewing gum composition or a confectionery composition containing an encapsulated stain removing agent selected from anionic and non-ionic surfactants and methods of preparing and using the same to remove stains from dental material including teeth.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: October 14, 2014
    Assignee: Intercontinental Great Brands LLC
    Inventors: Samantha Katharine Holme, Shiuh John Luo
  • Publication number: 20140294915
    Abstract: A chewing gum with a liquid-fill composition and a surrounding gum region, with one or both containing active ingredients, such as herbal, medicinal and/or mineral elements or combinations thereof, present in an amount of at least about 0.05 mg.
    Type: Application
    Filed: May 21, 2014
    Publication date: October 2, 2014
    Inventors: Jack Barreca, Joseph E. Kovarik
  • Patent number: 8828423
    Abstract: A delivery system for inclusion in an edible composition is formulated to have at least one active component encapsulated within an encapsulating material, whereby the delivery system has a tensile strength suitable for delivering the active component at a desired release rate.
    Type: Grant
    Filed: March 21, 2005
    Date of Patent: September 9, 2014
    Assignee: Intercontinental Great Brands LLC
    Inventors: Navroz Boghani, Petros Gebreselassie
  • Publication number: 20140234392
    Abstract: A nicotine-containing particulate material for release of nicotine, the material comprising a combination of nicotine or a pharmaceutically acceptable salt, complex or solvate thereof and a microcrystalline cellulose, The particulate material is stable upon storage and releases nicotine relatively fast. The particulate material can be used in the manufacture of nicotine-containing pharmaceutical composition, wherein the release of nicotine can be designed to be relatively fast so as to obtain a fast onset of action.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 21, 2014
    Applicant: Niconovum AB
    Inventors: Henri Hansson, Arne Kristensen
  • Patent number: 8784872
    Abstract: Formulations have been developed which assist individuals having an addiction such as smoking to reduce or quit engaging in the addictive behavior. Representative behaviors include smoking, excessive alcohol or food ingestion, drug addiction, and ingestion of caffeine or junk food providing quick “highs”. The formulations assist the smoker to become dissatisfied with smoking, until he or she willingly gives up the habit or at least cuts down on the number of cigarettes smoked per day as an initial step towards quitting in the future. The formulations can also be used in conjunction with other known formulations, such as nicotine gum or patch. The formulations contain hydrophilic polymers, for example, polyethylene glycol (PEG) alone or in combination or polyvinyl pyrrolidone (PVP) (also known as povidone or polyvidone alone or in combination.), sweeteners and/or flavorings, viscosity modifiers/binders, and pH or buffering agents.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: July 22, 2014
    Assignee: Comgenrx, Inc.
    Inventors: Bryan T. Oronsky, Neil C. Oronsky, Arnold L. Oronsky
  • Patent number: 8784781
    Abstract: The present invention features a process for making a chewing gum product including the steps of forming a powder blend containing a gum base into the desired shape of the chewing gum product and applying radiofrequency energy to the shape for a sufficient period of time to soften the gum base to fuse the shape into the chewing gum product.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: July 22, 2014
    Assignee: McNeil-PPC, Inc.
    Inventors: Gregory E. Koll, Harry S. Sowden, Joseph R. Luber, Leo B. Kriksunov, Frank J. Bunick, Jen-Chi Chen, Roland Olsson, Christopher E. Szymczak
  • Publication number: 20140154301
    Abstract: A method is provided of making a medicinal delivery system which satiates a craving in an individual when the medicinal delivery system is administered orally to the individual. A coating composition is applied on a saliva-soluble powder to establish a coated powder, the coating composition featuring an at least partially solubilized craving satiation medicinal compound. The coated powder is combined with an edible carrier base to establish a medicinal delivery system that rapidly releases medicine and buffer preferably followed by slower, sustained release.
    Type: Application
    Filed: February 4, 2014
    Publication date: June 5, 2014
    Applicant: JSRNTI, LLC
    Inventors: Tommy L. CHAU, John M. PINNEY, Jack E. HENNINGFIELD, Edward J. CONE, Saul M. SHIFFMAN, Joseph G. GITCHELL
  • Patent number: 8685436
    Abstract: The invention relates to hydroxyflavanones, their salts and stereoisomers and their mixtures for suppressing or reducing the bitter and/or metallic taste impression. In addition, the invention relates to nutritional, nutritive or consumable preparations or oral pharmaceutical compositions, characterized in that these have an active content of hydroxyflavanones, their salts and stereoisomers or their mixtures.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: April 1, 2014
    Assignee: Symrise AG
    Inventors: Jakob Peter Ley, Gerhard Krammer, Günter Kindel, Ian-Lucas Gatfield, Manfred Müller
  • Patent number: 8679522
    Abstract: A chewing gum with a liquid-fill composition and a surrounding gum region, with one or both containing active ingredients, such as herbal, medicinal and/or mineral elements or combinations thereof, present in an amount of at least about 0.05 mg.
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: March 25, 2014
    Inventor: Jack Barreca
  • Publication number: 20140079756
    Abstract: A compressed chewing gum tablet includes at least a first and a second chewing gum module, the first chewing gum module including a first chewing gum composition including at least a first active ingredient and chewing gum granules containing gum base, the second chewing gum module including a second chewing gum composition including at least a second active ingredient and chewing gum granules containing gum base, wherein the first active ingredient is a pharmaceutically active ingredient, and the second active ingredient is selected from the group consisting of pharmaceutically active ingredients and enhancers, wherein the gum base content of the first and second chewing gum modules is different.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 20, 2014
    Inventors: Carsten Andersen, Gitte Lorenzen, Nicolai Arent, Bitten Thorengaard, Helle Wittorff
  • Patent number: 8658200
    Abstract: A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.
    Type: Grant
    Filed: October 28, 2012
    Date of Patent: February 25, 2014
    Assignee: McNeil-PPC, Inc.
    Inventors: Seema Mody, Gregory Koll
  • Patent number: 8642011
    Abstract: The present invention relates to an isolated microorganism belonging to the genus Mycobacterium, characterized in that it comprises inactivating the gene Rv0757 that confers a PhoP? phenotype and inactivating a second gene that prevents the production of DIM (DIM-phenotype). Additionally, the present invention comprises the use of said microorganism for producing a vaccine for immunizing against or preventing tuberculosis.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: February 4, 2014
    Assignee: Universidad de Zaragoza
    Inventors: Carlos Martin Montanes, Brigitte Gicquel, Esther Perez Herran, Jesus Gonzalo Asensio, Ainhoa Arbues Arribas
  • Publication number: 20130330396
    Abstract: The physiological cooling agent N-ethyl-2,2-diisopropylbutanamide exhibits a surprising selectivity for throat cooling over mouth cooling, especially when consumed in the form of a confection. Methods of treating throat discomfort using N-ethyl-2,2-diisopropylbutanamide are described. Also described are various confections that incorporate N-ethyl-2,2-diisopropylbutanamide, including hard candy confections, soft candy confections, and center-filled confections.
    Type: Application
    Filed: August 15, 2013
    Publication date: December 12, 2013
    Applicant: INTERCONTINENTAL GREAT BRANDS LLC
    Inventors: Michel Cornec, Beth Ann Correa, Michelle Harnish, Joan E. Harvey, Caroline Lynch, Danielle Schwartz, Deborah L. Watson
  • Patent number: 8603516
    Abstract: A lozenge is provided that has stable pH and stable levels of active ingredient over time. It comprises a combination of (i) at least one gum and (ii) at least one non-crystallising sugar or non-crystallising sugar alcohol in a matrix designed for controlled buccal delivery of a drug. The lozenge also contains water and optional components selected from flavorings, taste masking agents, colorings, buffer components, pH adjusting agents, excipients, stabilizers and sweeteners. Methods of preparing the lozenge are also provided.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: December 10, 2013
    Assignee: Gelmedic Holding APS
    Inventors: Anders Dam, Janos Major, Peter Tasko
  • Patent number: 8603517
    Abstract: A lozenge is provided that has stable pH and stable levels of active ingredient over time. It comprises a combination of (i) at least one gum and (ii) at least one non-crystallising sugar or non-crystallising sugar alcohol in a matrix designed for controlled buccal delivery of a drug. The lozenge also contains water and optional components selected from flavorings, taste masking agents, colorings, buffer components, pH adjusting agents, excipients, stabilizers and sweeteners. Methods of preparing the lozenge are also provided.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: December 10, 2013
    Assignee: Gelmedic Holdings APS
    Inventors: Anders Dam, Janos Major, Peter Tasko