Food Or Edible As Carrier For Pharmaceutical Patents (Class 424/439)
  • Patent number: 10258074
    Abstract: Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: April 16, 2019
    Assignee: Wisonsin Alumni Research Foundation
    Inventors: Denise M. Ney, Mark R. Etzel
  • Patent number: 10245247
    Abstract: Embodiments of the present invention are directed to methods, apparatus and articles of manufacture that feature omega-3 fatty acids co-processed with flavonoid and lipophilic antioxidants for improved stability.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: April 2, 2019
    Assignee: AMBO INNOVATIONS, LLC
    Inventors: Bo Martinsen, Leif Andreas Riege
  • Patent number: 10231467
    Abstract: The invention relates to a process for manufacturing a solid fermented soy milk product, comprising a fermentation step in which a fermentation substrate containing soy milk and with adjusted malic acid and free amino acid concentrations, is fermented with heterofermentative lactic acid bacteria.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: March 19, 2019
    Assignee: Sapporo Holdings Limited
    Inventor: Norihiko Tsuchimoto
  • Patent number: 10226445
    Abstract: Pharmaceutical preparations are proposed, comprising bitter-masking acting substances for reducing and/or inhibiting gastric acid secretion induced by food constituents.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: March 12, 2019
    Assignee: Symrise AG
    Inventors: Elke Köck, Jakob Ley, Veronika Somoza, Kathrin Liszt, Sabine Widder
  • Patent number: 10219522
    Abstract: A composition includes Punica extract and a Lamiaceae extract, wherein a majority of the volatile oil components have been removed from the Lamiaceae extract. A method for applying the composition to a food which includes but is not limited to fresh/unprocessed and processed meat, fish or poultry is also provided.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: March 5, 2019
    Assignee: NATUREX S.A.
    Inventors: Mélanie Marie-Paule Patricia Heudré, Simona Birtic, François-Xavier Henri Pierre, Xavier Pierre François Mesnier, Anne Passemard, Antoine Charles Bily, Marc Roller
  • Patent number: 10206421
    Abstract: Dry stabilizing compositions for bioactive materials include sugars and hydrolyzed proteins, and may be formed into tablets or other forms providing enhanced stability for the bioactive material. Compositions containing the bioactive materials may be produced by a method that includes (a) combining the bioactive material with other ingredients in an aqueous solvent to form a viscous slurry; (b) snap-freezing the slurry in liquid nitrogen to form solid frozen particles, beads, droplets or strings; (c) primary drying by water removal under vacuum of the product of step (b) while maintaining it at a temperature above its freezing temperature; and (d) secondary drying of the product of step (c) at maximum vacuum and a temperature of 20° C. or higher for a time sufficient to reduce the water activity to below 0.3 Aw.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: February 19, 2019
    Assignee: Advanced BioNutrition Corp.
    Inventors: Moti Harel, Qiong Tang, Trisha Rice, Kimberly Jennings, Brian Carpenter, Roger Drewes, Elizabeth Raditsis, January Scarbrough
  • Patent number: 10201551
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: February 12, 2019
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Patent number: 10194668
    Abstract: The disclosure concerns a method for producing a layered cookie comprising at least one biscuit and a filling, the layered cookie containing 10 wt % to 25 wt % fat and 15 wt % to 40 wt % sugar, wherein the slowly-digestible-starch-over-total-available-starch ratio of the layered cookie is at least 31 wt %, the method including: forming a dough comprising a cereal flour, fat, sugar and at most 8 wt % added water relative to the total weight of the dough; molding the dough into the shape of a biscuit; baking the biscuit; and assembling the biscuit with a filling to form a layered cookie; wherein the cereal flour comprises refined cereal flour, in an amount of at least 21 wt % over the total weight of the dough, with a water absorption under 55% as measured by Brabender® Farinograph®.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: February 5, 2019
    Assignee: Generale Biscuit
    Inventors: Lionel Lanvin, Agathe Arlotti, Aliette Verel
  • Patent number: 10188129
    Abstract: An edible composition comprising starch and cellulose ether particles, wherein at least 10 volume percent of the cellulose ether particles have a particle length LEFI of less than 40 micrometers, is useful for preparing a batter by mixing the edible composition with water. The batter is contacted with a food to prepare a battered food. The battered foods have a reduced oil and/or fat uptake when fried, as compared to fried non-battered food.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: January 29, 2019
    Assignee: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Robert B. Fletcher, Jing Guo, Jorg Theuerkauf, Sjoerd A. De Vries
  • Patent number: 10172788
    Abstract: The present invention relates to chewing gum containing a synergic combination of zinc and vegetable extracts containing polyphenols. Said chewing gum is useful in treating the symptoms of halitosis.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: January 8, 2019
    Assignee: PERFETTI VAN MELLE S.P.A.
    Inventors: Roberto Colle, Andrea Sarrica, Maurizio Deleo
  • Patent number: 10159269
    Abstract: A composition containing a Lactobacillus pentosus TUA4337L strain (accession number: NITE BP-1479), characterized in that the strain has proliferation ability in the small intestines and/or the large intestine, and preferably the small intestines, after having survived in the intestinal tract. Since the composition of the present invention contains lactic acid bacteria having proliferation ability in the intestinal tract, when ingested in the body, the lactic acid bacteria survive to the intestinal tract and proliferate, whereby the fat absorption can be blocked, and the weight gains can be blocked, so that the composition can be suitably used for the purposes of dieting effects.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: December 25, 2018
    Assignee: SUNTORY HOLDINGS LIMITED
    Inventor: Eiji Fukushima
  • Patent number: 10159699
    Abstract: Described is a system for affecting intestinal microbial flora. The system includes an intestinal sleeve that is implanted in a patient and bypasses a section of the intestine; and probiotics, prebiotics or pharmacologic therapy used in combination with the intestinal sleeve. Also described are related methods.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: December 25, 2018
    Assignee: METAMODIX, INC.
    Inventors: Kedar R. Belhe, Todd Stangenes
  • Patent number: 10155815
    Abstract: The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: December 18, 2018
    Assignee: Roche Glycart AG
    Inventors: Marina Bacac, Thomas Hofer, Ralf Hosse, Christiane Neumann, Christian Klein, Ekkehard Moessner, Pablo Umana, Tina Weinzierl
  • Patent number: 10143225
    Abstract: An edible composition comprising starch and cellulose ether particles, wherein the cellulose ether particles have a median Equivalent Projected Circle Diameter (EQPC 50,3) of up to 110 micrometers and a Crystallinity Index, CI, of not more than 0.43, wherein CI=(I200?1am)/I200> where I200 is the intensity of the highest peak in the X-ray diffraction spectral pattern of the cellulose ether particles and Iam is the intensity of the valley between the highest peak I200 and the higher of the one or two peaks adjacent to the highest peak, is useful for preparing battered foods of reduced oil and/or fat uptake when fried.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: December 4, 2018
    Assignee: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Jing Guo, Jorg Theuerkauf
  • Patent number: 10143701
    Abstract: The invention relates to a method for the production of a time-stable, solid appetizing composition and to the use thereof, said composition comprising at least one active substance which is introduced in the final production step, by adding same to the already formed mixture of other components at ambient temperature, without the use of water or heat. The composition is intended for use as a drug, a nutraceutical or a food supplement for oral administration to mammals, except humans, in particular for pets such as dogs, cats or horses. The stable solid composition is obtained by compressing the mixture using a press for compressing formulations having a high fat content.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: December 4, 2018
    Assignee: FRIULCHEM SPA
    Inventors: Guy Derrieu, Giancarlo Mazzola
  • Patent number: 10143206
    Abstract: An edible composition comprising starch and cellulose ether particles, wherein the cellulose ether particles have a ratio M3.0/M2.0 of not more than 200 micrometers, wherein M3.0 is the number volume mean and M2.0 is the number surface area mean of the cellulose ether particles, and/or wherein the cellulose ether particles have a volume fraction of fibrous particles of no more than 40%, is useful for preparing a batter by mixing the edible composition with water. The batter is contacted with a food to prepare a battered food. The battered foods have a reduced oil and/or fat uptake when fried, as compared to fried non-battered food.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: December 4, 2018
    Assignee: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Jorg Theuerkauf, Robert B. Fletcher, Yvonne M. Goerlach-Doht, Juergen Hermanns, Sjoerd A. De Vries
  • Patent number: 10124815
    Abstract: A rail vehicle includes a chassis, a vehicle structure and a support unit disposed at the end face of the rail vehicle. The vehicle is comparatively lightweight and economical and can also advantageously perform other tasks in addition to supporting a track reamer. The support unit includes a plateau section which is part of the vehicle structure and includes a climbing protection device on its end face and a track reamer holder for supporting a track reamer. The track reamer holder is disposed below the plateau section and is rigidly secured thereto.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: November 13, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Stephan Drexler, Manuel Kroiss, Hannes Peer, Christian Winkelmann
  • Patent number: 10111925
    Abstract: The present invention is related to a formulation comprising Hedera helix, Pelargonium sidoides, and Zingiber officinale extracts to be used in the treatment, prevention of various respiratory diseases or alleviation and/or elimination of symptoms thereof and a method for preparing said formulation.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: October 30, 2018
    Assignee: MONTERO GIDA SANAYI VE TICARET A.S.
    Inventors: Ümit Cifter, Nazife Arabacioglu, Özlem Toker
  • Patent number: 10098903
    Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: October 16, 2018
    Assignees: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion
    Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
  • Patent number: 10092625
    Abstract: Heat-treated liquid enteral nutritional composition with a low monovalent metal ion content are provided that contain micellar casein and optionally caseinate, and in which the total amount of monovalent metal ions is less than 25 mg/g of protein. Also, heat-treated liquid enteral nutritional compositions are disclosed comprising 10 to 20 g of protein per 100 ml of the composition, in which all or a major part of said protein comprises micellar casein. Also, a method is disclosed for producing the composition according to the invention, comprising a step wherein an aqueous protein solution in which all or a major part of said protein comprises micellar casein, is subjected to an evaporation step.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: October 9, 2018
    Assignee: N.V. Nutricia
    Inventors: Marcel Minor, Suzanne Van Steenis, Hilde Ruis
  • Patent number: 10080718
    Abstract: The present invention relates generally to a methods of treating ear infections and clearing excess fluid from Eustachian tubes.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: September 25, 2018
    Assignee: TRY THIS FIRST, INC.
    Inventor: Scott Morehouse
  • Patent number: 10076553
    Abstract: A dietary product for preventing cardiometabolic risk in humans, in particular for reducing visceral fat and deep subcutaneous fat, includes in particular a mixture of: a whey hydrolysate having a molecular weight of between 200 and 10,000 daltons, an isolate and/or concentrate of whey, and calcium caseinate.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: September 18, 2018
    Assignee: INTERNATIONAL NUTRITION RESEARCH COMPANY
    Inventor: Claude Vincent
  • Patent number: 10066953
    Abstract: It is an object of the present invention to provide a destination estimating system and a destination estimating method capable of estimating a destination with a high degree of accuracy even when a user uses a detour or stops off somewhere.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: September 4, 2018
    Assignee: MITSUBISHI ELECTRIC CORPORATION
    Inventors: Yuko Ota, Masahiko Ikawa, Hiroki Konaka, Ryusuke Kinoshita
  • Patent number: 10064849
    Abstract: The invention relates to pharmaceutical compositions for direct systemic introduction, are also known as DSI pharmaceutical compositions, for used as human veterinary pharmaceutical compositions. In one embodiment, the invention relates to a pharmaceutical composition for direct system introduction comprising bovine gelatin, mannitol, an optional surfactant, an optional flavorant, and an active pharmaceutical ingredient. A DSI pharmaceutical composition of the invention has a disintegration time of 7 seconds or less in deionized water maintained at 37.0° C.±0.5° C. The invention also relates to a method of delivering an active pharmaceutical ingredient to an animal comprising the step of placing a DSI pharmaceutical composition of the invention into a mucosal cavity of an animal to be treated with the active pharmaceutical ingredient and to the corresponding methods of treatment.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: September 4, 2018
    Assignee: NEW MARKET PHARMACEUTICALS
    Inventors: Mark Ridall, David Rock
  • Patent number: 10046015
    Abstract: The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: August 14, 2018
    Assignee: 4D Pharma Research Limited
    Inventors: Imke Elisabeth Mulder, Amy Beth Holt, Seanin Marie McCluskey, Grainne Clare Lennon, Suaad Ahmed
  • Patent number: 9999606
    Abstract: An oral pharmaceutical composition of isotretinoin and a carrier substrate, having isotretinoin in the form of gel, dispersion, solution or emulsion, which is absorbed onto the carrier substrate to form solid particles, powder, or granules. The oral pharmaceutical composition has enhanced bioavailability. A process is used for preparing the oral composition.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: June 19, 2018
    Assignee: Sun Pharmaceutical Industries Limited.
    Inventors: Rajesh Rao, Anuj Kumar Fanda, Satish Kumar Jain, Romi Barat Singh
  • Patent number: 9999235
    Abstract: The invention relates to a ready-to-drink tea beverage comprising water, tea solids, protein and primary cell wall material. The primary cell wall material is derived from plant parenchymal tissue and has been treated to contain at least partially disentangled cellulose microfibrils. The invention further relates to a method for preparing said ready-to-drink tea beverage comprising the steps of •—mixing at least part of the water and primary cell wall material; and •—subjecting this mixture to mechanical energy and/or cavitation.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: June 19, 2018
    Assignee: Conopco, Inc.
    Inventors: Remco Joannes Koppert, Krassimir Petkov Velikov
  • Patent number: 9993454
    Abstract: The present invention belongs to the fields of pharmacology, medicine and medicinal chemistry. The present invention provides novel pharmaceutical compositions composed of solid nanoparticles dispersed in aqueous medium of substantially water insoluble pharmaceutical substances such as docetaxel with reduced Ostwald ripening.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: June 12, 2018
    Assignee: Luminus Biosciences, Inc.
    Inventor: Chandra Ulagaraj Singh
  • Patent number: 9931365
    Abstract: Nutrient compositions comprising botanical extracts and an omega 3 fatty acid as well as methods of their use for treating, inter alia, autism or apraxia and/or ameliorating one or more symptoms thereof are disclosed. The use of such compositions for enhancing cognitive function and/or one or more aspects thereof, or for treating stroke or seizures and/or ameliorating one or more symptoms thereof are also disclosed.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: April 3, 2018
    Inventor: Lisa Geng
  • Patent number: 9931297
    Abstract: An edible animal medicine container for delivering medicine or other ingestible material, contained therein, to an animal, includes first and second edible housing shells. The first shell includes a first peripheral ledge, surrounding a first central hollow, and a first interlocking feature extending therefrom. The second shell includes a second peripheral ledge, surrounding a second central hollow, and a second interlocking feature extending into, and at least partially defined by, the second peripheral ledge. The second shell is positionable relative to, and connectable to, the first shell to define an interior in which the ingestible material may be disposed. In such connected state the first interlocking feature is seated and frictionally held within the second interlocking feature of the second edible housing shell so as to retain the first and second shells together and thereby retain the ingestible material within the interior until ingested by an animal.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: April 3, 2018
    Assignee: Make Ideas, LLC
    Inventors: Keith Alan Mullin, William Bradley Allen
  • Patent number: 9925117
    Abstract: A pre-filled syringe storing an anesthetic is disclosed. The pre-filled syringe includes a container configured to store a liquid anesthetic solution. The liquid anesthetic solution includes an anesthetic, water, and a solvent. The container is made of a plastic that is inert to the anesthetic. The pre-filled syringe also includes a plunger made of siliconized bromobutyl rubber that is inert to the anesthetic and a rubber stopper made of siliconized bromobutyl rubber that is inert to the anesthetic. The plunger and the rubber stopper seal the container configured to store the liquid anesthetic solution.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: March 27, 2018
    Assignee: Fresenius Kabi USA, LLC
    Inventors: Neil P. Desai, Andrew Yang, Sherry Xiaopei Ci
  • Patent number: 9913810
    Abstract: A dietary supplement composition and associated method of use has the composition formulated in a therapeutic amount to treat and alleviate symptoms of joint pain in a person having joint pain. The composition includes astaxanthin and microbial fermented, low molecular weight hyaluronic acid or sodium hyaluronate (hyaluronan). The composition also includes at least one of a phospholipid, glycolipid, and sphingolipid. It is formulated into an oral dosage form and the astaxanthin is 0.1 to 15 percent by weight of the at least one phospholipid, glycolipid, and sphingolipid.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: March 13, 2018
    Assignee: U.S. NUTRACEUTICALS, LLC
    Inventors: John A. Minatelli, W. Stephen Hill, Rudi E. Moerck
  • Patent number: 9895403
    Abstract: Methods of producing high purity palmitoleic acid esters from natural oils are disclosed. The natural oils may comprise plant oil, nut oil, microalgae oil, and fish oil. The methods of processing the natural oil comprise transesterification with ethanol as the reacting solvent to produce ethyl esters. Methods of producing a high purity fraction of Omega-3, 6, & 9 fatty acid esters from natural oils are also disclosed. The high purity fatty acid esters may be used in nutrition, cosmetic, and nutraceutical products.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: February 20, 2018
    Assignee: HELIAE DEVELOPMENT LLC
    Inventors: Sandip Shinde, Stephen Ventre, Jennifer Lloyd-Randolfi, Mike Lamont
  • Patent number: 9885005
    Abstract: [Problem] To provide a phospholipid ?-linolenic acid composition of consistent quality and having a stable supply of source material, with focus on Torula yeast, which is edible and recognized as safe, in order to resolve issues with omega 3 sources. [Means for Solving the Problem] As a result of intensive study to resolve the above-noted issues, the inventors of the present invention have discovered that a phospholipid ?-linolenic acid composition can be obtained using residue of yeast extract extracted from Torula yeast (Candida utilis), for example, which is currently produced in large quantities for application in foods, and so arrived at the present invention.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: February 6, 2018
    Assignees: KOHJIN LIFE SCIENCES CO., LTD., HIROSAKI UNIVERSITY
    Inventors: Naoto Kaji, Shiroh Aida, Katsuhiro Osaki, Masato Omae, Tomohiro Nakagawa, Motoyuki Tokuriki, Hayato Maeda
  • Patent number: 9861656
    Abstract: Sperm mobility and impregnation of an oocyte is enhanced by placing sperm in an aqueous solution of phospholipids prior to in vitro fertilization or artificial insemination. The aqueous phospholipid solution can also be used during storage or cryopreservation of the sperm. Also, the motility of sperm produced or ejaculated and the environment into which it is placed is enhanced my ingestion of the phospholipid composition by the male or female, or a vaginal placement of compositions containing the phospholipids.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: January 9, 2018
    Assignee: ALLERGY RESEARCH GROUP, LLC
    Inventors: Garth Nicolson, Gonzalo Ferreira de Mattos, Robert A. Settineri
  • Patent number: 9849091
    Abstract: This invention provides a solid oral formulation including a tablet core surrounded by an iron sugar overcoat so that the iron sugar overcoat makes at least some elemental iron content available for gastrointestinal absorption relative to the tablet core while counteracting at least some of the constipation associated with oral iron consumption, and further includes methods of administering the solid oral formulation.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: December 26, 2017
    Inventor: Jugal K. Taneja
  • Patent number: 9844532
    Abstract: This invention relates to a method of improving CNS maturation in an infant by administering a mixture of natural tocopherols, wherein the composition contains an optimum tocopherol profile similar to that found in human breast milk, and can encompass a tocopherol profile from early stage to transitional to mature human breast milk. For ease of administration and maximized efficacy, the optimized mixture of natural tocopherols are typically delivered in an oral dosage form with a limited level of non-RRR alpha-tocopherols to maximize efficacy of the RRR alpha-tocopherol on stimulating post-natal CNS development.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 19, 2017
    Assignee: Abbott Laboratories
    Inventors: Chron-Si Lai, Matthew Kuchan, Gary Katz
  • Patent number: 9839662
    Abstract: The invention provides a composition the prevention and treatment of cardiovascular disease, wherein said composition compounds obtained from palm oil mill effluents, in particular from vegetative liquor from the milling of palm oil fruit.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: December 12, 2017
    Assignee: MALAYSIAN PALM OIL BOARD
    Inventors: Hjh Che Anishas HJ. Che Idris, Nagendran Balasundram, Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram P. Manickam, Mohd Basri Wahid
  • Patent number: 9827218
    Abstract: Embodiments of the present invention are directed to methods, apparatus and articles of manufacture that feature omega-3 fatty acids co-processed with flavonoid and lipophilic antioxidants for improved stability.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: November 28, 2017
    Assignee: AMBO INNOVATIONS, LLC
    Inventors: Bo Martinsen, Leif Andreas Riege
  • Patent number: 9789076
    Abstract: A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of active delivered via two or three administrations (b.i.d. or t.i.d.) using current delivery modalities. The method reduces the rate of occurrence of common adverse events with hydroxycitric acid salts, and reduces the occurrence of reverse effects on diets high in fat and/or alcohol. The method improves the uptake of the active compound thereby reducing the dose required.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: October 17, 2017
    Assignee: GLYKON TECHNOLOGIES GROUP, LLC
    Inventors: Dallas L. Clouatre, Daniel E. Clouatre, Brad J. Douglass
  • Patent number: 9782487
    Abstract: The invention described herein provides a preparation comprising a non-mammalian derived mixture of serine glycerophospholipid conjugates with a specific content and specific conjugation patterns of LA, linolenic acid (alpha-linolenic acid, gamma-linolenic acid) DHA and EPA which depend on utilizing different sources of lipids, and uses of such preparations.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: October 10, 2017
    Assignee: ENZYOMTEC LTD.
    Inventors: Gai Ben Dror, Dorit Platt, Orly Farkash, Rassan Zuabi, Zohar Bar-On, Avidor Shulman, Dori Pelled, Yael Richter
  • Patent number: 9770440
    Abstract: A solid oral pharmaceutical composition for delivery of a pharmaceutically acceptable active ingredient to an animal where the composition comprises an isoxazoline compound, a solvent and an excipient, a process for the manufacture of such solid oral pharmaceutical composition and a method of controlling a parasite infection administering such solid oral pharmaceutical composition.
    Type: Grant
    Filed: April 3, 2013
    Date of Patent: September 26, 2017
    Assignee: Intervet Inc.
    Inventors: Keith Freehauf, Niki Waldron, Jürgen Lutz, Frank Guerino
  • Patent number: 9750711
    Abstract: The present invention provides a low dose oral pharmaceutical composition of isotretinoin having reduced food effect, in particular no food effect. The present invention further relates to a process for preparing the oral pharmaceutical composition of the present invention.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: September 5, 2017
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Harish Kumar Madan, Rathinasabapathy Venkateshwaran, Sumit Madan, Ravi Kochhar
  • Patent number: 9737564
    Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: August 22, 2017
    Assignees: New York University, General Hospital Corporation, The Regents of the University of California
    Inventors: David S. Goldfarb, Brian Eisner, John Asplin, Marshall L. Stoller
  • Patent number: 9731015
    Abstract: Methods and formulations for increasing the water solubility and/or bioavailability of a lipophilic natural compounds is disclosed. The formulations may be employed to make liquid filled capsules or clear and stable beverages containing therapeutic amounts of the active ingredients, for example.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: August 15, 2017
    Inventor: Eric Hauser Kuhrts
  • Patent number: 9707079
    Abstract: A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 24-45% CaO, 34-50% SiO2, 0-25% Na2O, 5-17% P2O5, 0-5% MgO and 0-1% CaF2 by mass percent, produced by mixing with pore forming agents and specified heat treatments.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: July 18, 2017
    Assignee: NOVABONE PRODUCTS, LLC
    Inventors: Jiang Chang, Weiming Gu, Jipin Zhong
  • Patent number: 9707241
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: July 18, 2017
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Patent number: 9693972
    Abstract: Described herein are methods, compositions, systems, and kits that effectively deliver a laxative to a patient along with effective electrolyte replenishment by delivering both a laxative and electrolytes via a food item. The food item is prepared by either combining, mixing, or integrating the ingredients that form the food item together with one of or both of a laxative and electrolytes so that the ingredients in the food item either eliminate or significantly reduce the poor taste associated with either the electrolytes or the laxative. Eliminating or reducing the poor taste associated with either electrolytes or laxative, greatly improves patient satisfaction and compliance with ingesting these substances in order to, for example, prepare the GI tract of the patient for a medical or surgical procedure.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: July 4, 2017
    Assignee: COLONARYCONCEPTS LLC
    Inventors: Michael Allio, Jonathan Gordon
  • Patent number: 9675097
    Abstract: Disclosed herein are shelf-stable, clear liquid nutritional compositions having a pH ranging from 2.5 to 4.6 and comprising water; at least one source of EGCg in an amount sufficient to provide 200-1700 mg/L of EGCg; and at least one source of protein in an amount sufficient to provide 25-45 g/L of total protein. The shelf-stable, clear liquid nutritional compositions lose no more than 20% by weight solids of the EGCg content present in the initial formulation of the compositions to epimerization, degradation, or both epimerization and degradation during heat sterilization. In certain embodiments, the loss of EGCg is exhibited by the amount of epimerization product GCg present in the shelf-stable, clear liquid nutritional composition following heat sterilization. Methods for preparing the shelf-stable, clear liquid nutritional compositions are also disclosed herein.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: June 13, 2017
    Assignee: ABBOTT LABORATORIES
    Inventors: Gaurav Patel, Paul Johns, Normanella Dewille, Suzette Pereira
  • Patent number: 9649347
    Abstract: An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: May 16, 2017
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Wei Chen, Fengwei Tian, Wenli Huang, Jianxin Zhao, Hao Zhang, Gang Wang, Qiuxiang Zhang, Xiaoming Liu, Daming Fan, Feifei Chi