Natural Gums, Resin Or Latex Patents (Class 424/485)
  • Patent number: 10227301
    Abstract: The invention relates to the compounds of formula I, formula II, formula III, formula IV and formula V or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II, formula III, formula IV or formula V and methods for the treatment of inflammation and pain may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, oral solution, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of pain, oral mucosal inflammatory or oral infectious diseases.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: March 12, 2019
    Assignee: Cellix Bio Private Limited
    Inventor: Mahesh Kandula
  • Patent number: 10016442
    Abstract: Pharmaceutical gel compositions containing estrogen for vaginal administration, as well as a method of making the same, are disclosed.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: July 10, 2018
    Assignee: Allergan Pharmaceuticals International Limited
    Inventors: David Woolfson, Karl Malcolm
  • Patent number: 10011689
    Abstract: The present invention provides tissue expanders comprising biodegradable, chemically cross-linked hydrogels which are elastic in the dry state. These biocompatible tissue expanders are self-inflating and membrane-free. They swell slowly and elicit minimal negative tissue responses, while allowing for rapid and easy manipulation by the surgeon at the time of emplacement.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: July 3, 2018
    Assignees: Akina, Inc., THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Kinam Park, Clark Tobias Barco, Haesun Park, Yourong Fu, John Solomon Garner
  • Patent number: 9796872
    Abstract: The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions where the one polyelectrolyte present in molar excess is added in the form of a first aqueous solution during a mixing step to a second aqueous solution comprising the oppositely charged polyelectrolyte present in molar deficiency.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: October 24, 2017
    Assignee: The Clorox Company
    Inventors: David R. Scheuing, David J. Lestage, Carl W. Bennett, Mona M. Knock, Charles W. Scales, William L. Smith, Rui Zhang
  • Patent number: 9592201
    Abstract: A micro encapsulation material for use with storage unstable, therapeutic and nutritional agents which release the therapeutic and nutritional agents in predetermined locations in the gastro intestinal tract in which the microencapsulation material is formed by combining a food grade treated carbohydrate with a water soluble food grade protein. The therapeutic and nutritional agents form an oil phase which is emulsified with the water dispersed or dissolved encapsulant to encapsulate the therapeutic and nutritional agents. These agents may be oils or oil soluble or oil dispersible. The agents that may be encapsulated include lipids (oils including oxygen sensitive oils, fatty acids, triglycerides) and oil soluble and oil dispersible ingredients (including pharmaceuticals, probiotics, protein therapeutics and bioactives). The protein used may include any film forming water soluble protein or hydrolyzed protein and includes milk proteins such as casein and its derivatives or whey proteins.
    Type: Grant
    Filed: November 22, 2004
    Date of Patent: March 14, 2017
    Assignee: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Richard Head, Luz Sanguansri, Mary Ann Augustin
  • Patent number: 9566303
    Abstract: Compositions comprising ferrous and/or ferric iron compounds and fiber in a complex, methods for preparing such compositions of matter, and the use thereof for treatment of adsorbing certain accessible targets in the gastrointestinal tract and in an extracorporeal system, are provided herein.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: February 14, 2017
    Assignee: Vidasym, Inc.
    Inventor: Jinshyun Ruth Wu-Wong
  • Patent number: 9464051
    Abstract: The invention relates to the compounds of formula V or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula V and methods for the treatment of inflammation and pain may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, lozenge, spray, intravenous, oral solution, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of pain, oral mucosal inflammatory or oral infectious diseases.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: October 11, 2016
    Assignee: CELLIX BIO PRIVATE LIMITED
    Inventor: Mahesh Kandula
  • Patent number: 9381485
    Abstract: A method of encapsulating a volatile, water-soluble substance in capsules having a hydrogel shell and an oily interior includes (i) providing blank capsules having a hydrogel shell and an oily interior and (ii) immersing the capsules in an aqueous solution of the volatile, water-soluble substance for a time sufficient for them to load to a desired extent with the volatile, water-soluble substance. The aqueous solution additionally has dissolved therein to saturation point at least one water-soluble, non-volatile material. The method permits the easy and durable encapsulation of volatile materials that hitherto have been difficult to encapsulate.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: July 5, 2016
    Assignee: Givaudan S.A.
    Inventors: Robert B. Wieland, Jon C. Soper
  • Patent number: 9332777
    Abstract: Compositions containing modified gum acacia, less than 40% oil and carotenoids, where the gum acacia has been subjected to a heat-treatment at a temperature between 100° C. and 115° C. for 1 to 38 hours. These compositions allow preparation of emulsions having a very high color intensity and color stability and useful for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: May 10, 2016
    Assignee: DSM IP ASSETS B.V.
    Inventors: Andrea Hitzfeld, Bruno H. Leuenberger, Olivia Vidoni
  • Patent number: 9023392
    Abstract: Methods for administering a dermatological agent to a subject are provided. In the subject methods an effective amount of a topical formulation of the dermatological agent is topically applied to a host. The topically applied formulation of dermatological agent is then occluded with a hydrogel patch, where a feature of the hydrogel patch is that it lacks a pharmaceutically active agent. Also provided are methods of treating a subject for a disease condition by administering a dermatological agent to the subject. Also provided are kits for use in practicing the subject methods. The subject methods and compositions find use in a variety of different applications.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: May 5, 2015
    Assignees: Teikoku Pharma USA, Inc., Teikoku Seiyaku Kabushiki Kaisha
    Inventors: John Koo, Jutaro Shudo, Sadanobu Shirai
  • Patent number: 8986735
    Abstract: A solid dosage form containing a taste masked active agent is provided. The solid dosage form may be provided as a water soluble film that is disintegrable in the oral cavity to deliver and release the taste masked active agent. The disintegrable film includes at least one water soluble polymer and a taste masked ketoprofen active. Also provided are methods for preparing the solid dosage form and for using the solid dosage to administer an effective dosage of an active agent, such as ketoprofen, into the oral cavity for absorption.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: March 24, 2015
    Assignee: Novartis AG
    Inventors: Alexander M Schobel, Shyam S Vangala
  • Patent number: 8961939
    Abstract: Disclosed are compositions, apparatus, and related methods and systems for oral health care.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: February 24, 2015
    Assignee: NowSystem, Inc.
    Inventors: Janice Lou King, Dale Leland Winetroub
  • Patent number: 8920842
    Abstract: The present invention relates a biopolymeric liquid aqueous composition for producing self-gelling systems and gels, which comprises: an acidic water-based medium, 0.1 to 10% by weight of a pH-gelling acid-soluble biopolymer; and 0.1 to 10% by weight of a water-soluble molecule having a basic character and a pKa between 6.0 and 8.4, or a water-soluble residue or sequence of the molecule having a basic character and a pKa between 6.0 and 8.4. The liquid composition has a final pH ranging from 5.8 and 7.4, and forms a stable solid and homogeneous gel within a temperature range from 10 to 70° C. The present invention also relates to a method for preparing the composition and uses thereof.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: December 30, 2014
    Assignee: Piramal Healthcare (Canada) Ltd.
    Inventors: Abdellatif Chenite, Cyril Chaput, Dong Wang, Amine Selmani
  • Patent number: 8900623
    Abstract: The present invention is directed to a composition, kit and method for delivering a soft flowable gel to a flock of poultry in barns, but can also be used in hatcheries or free range farms, for treating poultry with a therapeutic agent. The soft flowable gel comprises water, a gelling agent, a therapeutic agent and between about 0.05% and 0.15% xanthan gum.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: December 2, 2014
    Assignee: Vetech Laboratories Inc.
    Inventor: Eng-Hong Lee
  • Patent number: 8889186
    Abstract: A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro dissolution test using USP Paddle method and using 0.1 N HCl as dissolution medium and has increased bioavailability by effectively reducing or even avoiding the effects of CYP3A4 metabolism. The modified composition may be coated with an enteric coating; and/or may comprise a solid dispersion or a solid solution of tacrolimus in a hydrophilic or water-miscible vehicle and one or more modifying release agents; and/or may comprise a solid dispersion or a solid solution of tacrolimus in an amphiphilic or hydrophobic vehicle and optionally one or more modifying release agents.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: November 18, 2014
    Assignee: Veloxis Pharmaceuticals A/S
    Inventors: Per Holm, Tomas Norling
  • Patent number: 8865214
    Abstract: Bioactive formulations and methods of use comprising a gypsum biopolymer matrix and soil beneficial microorganisms are described herein.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: October 21, 2014
    Assignee: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Syed H. Imam, Gregory M. Glenn, Farooqe Azam
  • Patent number: 8865215
    Abstract: Implants include a porous layer made from a composition including a compound wherein collagen is cross-linked to a glycosaminoglycan, the porous layer being optionally joined to a collagen film.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: October 21, 2014
    Assignee: Sofradim Production
    Inventors: Sébastien Ladet, Philippe Gravagna
  • Patent number: 8859487
    Abstract: A perfume tester or perfume includes a granule containing a friable peripheral portion incorporating fragrant compounds, which disintegrates as a perfumed powder when the granule is applied onto the skin. A method for making the perfume tester or perfume is by granulation, and the granule can be used in particular for perfume testing.
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: October 14, 2014
    Assignee: Laboratoires Docteur Gaetano Zannini
    Inventors: Jean-Pierre Mathonnet, Gaetano Zannini
  • Publication number: 20140294953
    Abstract: The disclosure relates to a sustained-release oral dosage form for once-a-day administration comprising a matrix containing a viscosity modifier and coated granules containing hydromorphone. The dosage form can have a release profile such that 16 hours following administration, less than about 85 percent of the hydromorphone is released. In addition, the dosage form may have alcohol and/or crush resistance.
    Type: Application
    Filed: June 5, 2014
    Publication date: October 2, 2014
    Inventors: Ehab Hamed, Manuel A. Vega Zepeda
  • Patent number: 8846769
    Abstract: A novel composition made of polyalkoxylated derivatives of trimethylolpropane and fatty alcohols, the composition lending itself to the preparation thereof and to the use thereof as a reversing agent for a reversible reverse latex.
    Type: Grant
    Filed: April 11, 2011
    Date of Patent: September 30, 2014
    Assignee: Societe d'Exploitation de Produits pour les Industries Chimiques SEPPIC
    Inventors: Paul Mallo, Herve Rolland, Georges Da Costa, Olivier Braun
  • Patent number: 8846092
    Abstract: Described are pharmacological compositions comprising a gum resin; a pharmacologically active agent and a topically acceptable volatile solvent for the gum resin and active agent. Also described are methods for the transdermal or transmucosal delivery of a pharmacologically active agent using such compositions.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: September 30, 2014
    Assignee: Jaleva Pharmaceuticals, LLC
    Inventors: Alex Battaglia, Eva Beim
  • Patent number: 8821933
    Abstract: Methods and compositions related polymers and hydrogels. In some cases to biodegradable hydrogels for use in medical applications are disclosed. The polymers and hydrogels may be produced from cross-linked dextran and poly(epoxides). The poly(epoxides) may be poloxamers.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: September 2, 2014
    Assignee: nanoDERM Sciences, Inc.
    Inventors: Roy R. Yeoman, Adrian S. Fox
  • Patent number: 8778396
    Abstract: This invention relates to an orally administrable, gastroretentive pharmaceutical dosage form which contains at least one pharmaceutically active ingredient and at least one polymeric adjuvant. The adjuvant serves to retain the dosage form in a selected region of the gastrointestinal tract for sufficient time for the pharmaceutically active ingredient to be released and absorbed. Ideally the dosage form will contain two or more pharmaceutically active ingredients which are delivered to different regions of the gastrointestinal tract.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: July 15, 2014
    Assignee: University of the Witwatersrand, Johannesburg
    Inventors: Viness Pillay, Yahya Choonara, Caragh Murphy, Sarashnee Moonisami
  • Patent number: 8728524
    Abstract: New biomaterials consisting of a combination of sulphated hyaluronic acid and gellan (as well as gellan that has not been associated with other polymers), to be used as a highly effective barrier to prevent post-surgical adhesions in abdominal, pelvic and, above all, spine surgery.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: May 20, 2014
    Assignee: Anika Therapeutics S.R.L.
    Inventors: Davide Bellini, Cristina Longinotti, Vittorio Crescenzi, Anna Taglienti
  • Patent number: 8722749
    Abstract: A method for producing foams, such as sponges, from hydrocolloids is described. A solid or semi-solid gel is formed by dissolving polymeric material in an aqueous solvent. The gel formed is allowed to set, and may optionally then be cut into the desired shape. The gel may be frozen to allow formation of ice crystals to act as porogens. Subsequently, the gel is exposed to a radiant energy field for drying under vacuum. This causes the solvent to boil and the foam or sponge is formed. Medicinally active ingredients may be included in the process, so that the sponge or foam formed contains the active ingredient dispersed within the structure. The method described provides an alternative to the conventional methods of particulate leaching or freeze drying.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: May 13, 2014
    Assignee: Enwave Corporation
    Inventors: Timothy D. Durance, Jaya Sundaram, Mareike Ressing
  • Patent number: 8722066
    Abstract: The present invention provides, compositions, devices, and methods for affecting, among other things, weight loss and/or weight control, by sequestering nutrients or other compounds such as toxins from absorption in the digestive tract. The compositions, devices, and methods employ one or more members made of a compressible, absorbent matrix material. In various embodiments, the matrix material is suitable for routine use. The compressible absorbent matrix material has a size, shape and/or geometry configured for efficient packing into a small space, and/or configured to absorb and substantially retain digested material in the stomach. The devices and compositions may further comprise one or more hydrogel(s), soluble or insoluble fibers, waxes and/or gums to provide the desired mechanical properties and/or absorptive or shielding properties.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: May 13, 2014
    Assignee: Primigenia, LLC
    Inventor: Paolo Costa
  • Patent number: 8703194
    Abstract: There is presently provided a stimulus-responsive polymer comprising a biodegradable polymer backbone and a stimulus-responsive pendant group attached to the biodegradable polymer backbone, wherein the biodegradable polymer backbone comprises a poly(amino ester) or a poly(amido amine), the poly(amido amine) optionally comprising a disulfide linkage in the backbone.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: April 22, 2014
    Assignee: Agency for Science, Technology and Research
    Inventors: Ye Liu, Decheng Wu, Chaobin He
  • Patent number: 8703195
    Abstract: Disclosed is a method in which poloxamer, a resin, and/or a tocopherol is/are fused, and the material that is to be treated is intimately dispersed with said melt. After being introduced into the melt, the material that is to be treated is coated with water to prevent hardening, and the spontaneously forming gel is homogenized. The obtained product is composed of a transparent gel that is based on at least one poloxamer, a resin or a tocopherol, and an active substance which is solubilized, dispersed, and stabilized therein and whose consistency ranges from solid, semisolid, i.e. aspic-like, to liquid. The micelles of said solubilized matter remain stable even when the same is diluted well below the CMC of poloxamer.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: April 22, 2014
    Assignee: Biorem AG
    Inventor: Hanspeter Strobel
  • Patent number: 8691277
    Abstract: The present invention relates to a long-acting sustained-release dosage form for treatment of Parkinson Disease, comprising a dopamine receptor agonist and a pharmaceutically acceptable biodegradable polymer accessories, wherein the content of the dopamine receptor agonist in the sustained-release dosage form is 5-50% by weight, and the content of the pharmaceutically acceptable polymer accessories is 50-95% by weight.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: April 8, 2014
    Assignee: Shandong Luye Pharmaceutical Co., Ltd.
    Inventor: Luping Zhang
  • Patent number: 8685454
    Abstract: A lubricating composition prepared primarily from organic materials (primarily plants and micro-organisms). The unique process and mixture of organic materials comprising this lotion provide with superior properties for various uses. The lotion exists as a viscous liquid with mucosa moistening properties. Some suggested applications for the lotion are that it may be used as a means for delivering medication, skin moisturizing and to enhances sexual experiences.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: April 1, 2014
    Assignee: Yes Syzygy Limited
    Inventor: Sarah Annabelle Brooks
  • Patent number: 8679523
    Abstract: The present invention comprises methods and compositions for delivery devices. More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide having oxygen and optionally active agents incorporated therein. The matrix may be formed into any desired shape for treatment of compromised tissue or for delivery of oxygen to a localized environment.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: March 25, 2014
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Bruce L. Gibbins, Lance D. Hopman
  • Patent number: 8679535
    Abstract: Disclosed are sustained release oral solid dosage forms comprising a therapeutically effective amount of a medicament having a solubility of more than about 10 g/l; a pH modifying agent; and a sustained release matrix comprising a gelling agent, said gelling agent comprising a heteropolysaccharide gum and a homopolysaccharide gum capable of cross-linking said heteropolysaccharide gum when exposed to an environmental fluid, said dosage form providing a sustained release of said medicament after oral administration to human patients.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: March 25, 2014
    Assignee: Endo Pharmaceuticals Inc.
    Inventors: Anand R. Baichwal, Troy W. McCall, Lirong Liu, Steve Labudzinski
  • Patent number: 8680161
    Abstract: The present invention relates to compositions containing plant gums and one or more fat-soluble active ingredients, wherein the composition comprises less than 40 weight-% oil, based on the total composition in dry matter. These compositions can be used for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions. The present invention also refers to the preparation of such compositions. The present invention furthermore refers to a process for the manufacture of a beverage by mixing the compositions with ingredients of beverages. The present invention also refers to beverages obtainable by this process.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: March 25, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Andrea Hitzfeld, Bruno H. Leuenberger, Olivia Vidoni
  • Patent number: 8658209
    Abstract: There is presently provided a stimulus-responsive polymer comprising a biodegradable polymer backbone and a stimulus-responsive pendant group attached to the biodegradable polymer backbone, wherein the biodegradable polymer backbone comprises a poly(amino ester) or a poly(amido amine), the poly(amido amine) optionally comprising a disulfide linkage in the backbone.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: February 25, 2014
    Assignee: Agency for Science, Technology and Research
    Inventors: Ye Liu, Decheng Wu, Chaobin He
  • Patent number: 8658207
    Abstract: The present invention provides pharmaceutical release systems comprising an therapeutically effective amount of flibanserin and at least one pharmaceutically acceptable excipient, characterized in that said pharmaceutical release systems exhibit a pharmacokinetic profile that is characterized by an average maximum flibanserin plasma concentration Cmax lower than 300 ng/mL, preferably lower than 200 ng/mL after administration of a single dose to healthy volunteers in fasted state or directly after a meal.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: February 25, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Wolfram Eisenreich, Thomas Friedl, Florian Sommer, Nantharat Pearnchob, Karl G. Wagner
  • Patent number: 8637440
    Abstract: A personal cleansing composition includes a surfactant, a thickener, emulsifier and at least one particulate dispersed in the thickener, the at least one particulate being formed of a substantially biodegradable substance. The at least one particulare may include a soy meal based polymer. The soy meal based polymer is both stable and biodegradable. The at least one particulate includes a group of suspended particles added to mechanically scrub the skin of a user or used as a textural ingredient to modify the feel, spreadability or slip of a product. The soy meal based polymer is useful in personal cleansing compositions as an exfoliant, a scrub, a film former or as a filler. The half-life of the composition may be modified as necessary based on the shelf-life of the product.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: January 28, 2014
    Inventor: Kim Cervino
  • Patent number: 8623411
    Abstract: A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro dissolution test using USP Paddle method and using 0.1 N HCl as dissolution medium and has increased bioavailability by effectively reducing or even avoiding the effects of CYP3A4 metabolism. The modified composition may be coated with an enteric coating; and/or may comprise a solid dispersion or a solid solution of tacrolimus in a hydrophilic or water-miscible vehicle and one or more modifying release agents; and/or may comprise a solid dispersion or a solid solution of tacrolimus in an amphiphilic or hydrophobic vehicle and optionally one or more modifying release agents.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: January 7, 2014
    Assignee: Veloxis Pharmaceuticals A/S
    Inventors: Per Holm, Tomas Norling
  • Patent number: 8617599
    Abstract: A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro dissolution test using USP Paddle method and using 0.1 N HCl as dissolution medium and has increased bioavailability by effectively reducing or even avoiding the effects of CYP3A4 metabolism. The modified composition may be coated with an enteric coating; and/or may comprise a solid dispersion or a solid solution of tacrolimus in a hydrophilic or water-miscible vehicle and one or more modifying release agents; and/or may comprise a solid dispersion or a solid solution of tacrolimus in an amphiphilic or hydrophobic vehicle and optionally one or more modifying release agents.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: December 31, 2013
    Assignee: Veloxis Pharmaceuticals A/S
    Inventors: Per Holm, Tomas Norling
  • Patent number: 8591870
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be formulated as solutions, solids, semisolids, microparticles, or crystals.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: November 26, 2013
    Assignee: Hallux, Inc.
    Inventors: Frank Kochinke, Corinne Bright
  • Patent number: 8586111
    Abstract: The hair gluing product of the invention is gel or crystallizing protective growth serum that dries down to form a film over your natural hair and scalp. The invention allows for application of hair bonding glue without damaging natural hair or scalp. It contains aloe extract, tea tree oil, chamomile extract. It is available in an assortment of colors. The purpose of the gel or serum is to protect client's natural hair/scalp from being damaged by the use of hair bonding glue, which is used for weaving styles. When hair bonding glue is applied directly to the natural hair and scalp it has a tendency to cause breakage and leads to damage hair the invention will cover the natural hair, which will allow the hair bonding glue to be applied directly to the shield that appears after the invention dries on the hair/scalp.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: November 19, 2013
    Inventor: Calvin Garris
  • Patent number: 8586084
    Abstract: A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro dissolution test using USP Paddle method and using 0.1 N HCl as dissolution medium and has increased bioavailability by effectively reducing or even avoiding the effects of CYP3A4 metabolism. The modified composition may be coated with an enteric coating; and/or may comprise a solid dispersion or a solid solution of tacrolimus in a hydrophilic or water-miscible vehicle and one or more modifying release agents; and/or may comprise a solid dispersion or a solid solution of tacrolimus in an amphiphilic or hydrophobic vehicle and optionally one or more modifying release agents.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: November 19, 2013
    Assignee: Veloxis Pharmaceuticals A/S
    Inventors: Per Holm, Tomas Norling
  • Patent number: 8568770
    Abstract: There is provided an adhesive preparation containing 5-methyl-1-phenyl-2-(1H)-pyridone. The adhesive preparation is a 5-methyl-1-phenyl-2-(1H)-pyridone-containing adhesive preparation including an active medicinal ingredient-containing layer, characterized in that the active medicinal ingredient-containing layer contains an lipophilic base, a dissolving agent (except glycerin and a medium-chain aliphatic acid triglyceride), and 5-methyl-1-phenyl-2-(1H)-pyridone or medically acceptable salts thereof.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: October 29, 2013
    Assignee: Lead Chemical Co., Ltd.
    Inventors: Takayasu Matsuzawa, Tamaki Horiuchi, Seijiro Yama, Sunao Takeuchi, Makoto Takeuchi
  • Patent number: 8563039
    Abstract: New biomaterials consisting of a combination of sulphated hyaluronic acid and gellan (as well as gellan that has not been associated with other polymers), to be used as a highly effective barrier to prevent post-surgical adhesions in abdominal, pelvic and, above all, spine surgery.
    Type: Grant
    Filed: October 3, 2005
    Date of Patent: October 22, 2013
    Assignee: Anika Therapeutics S.R.L.
    Inventors: Davide Bellini, Cristina Longinotti, Vittorio Crescenzi, Anna Taglienti
  • Patent number: 8557286
    Abstract: The invention relates to a method for producing pharmaceutical forms or preliminary stages thereof by means of extrusion. The pharmaceutical form has a matrix which the active agent is contained essentially, and whose essential characteristics are determined by the extrusion process and which comprises a polysaccharide and/or derivative thereof and/or a complex thereof and/or any mixture of the aforementioned substances with other substances and/or saccharides and/or derivatives thereof as an essential constituent, and at least one pharmaceutically active substance.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: October 15, 2013
    Assignee: EuroCeltique, S.A.
    Inventors: Hubert Rein, Klaus-Jurgen Steffens
  • Patent number: 8545886
    Abstract: The invention is directed to a Pharmaceutical extended release system, particularly for oral administration, of a pH-dependent water-soluble active substance, comprising or essentially consisting of a) flibanserin or a pharmaceutically acceptable derivative thereof as active substance; b) one or more pharmaceutically acceptable pH-dependent polymers; c) one or more pharmaceutically acceptable pH-independent polymers; d) one or more pharmaceutically acceptable acids; and e) optionally one or more additives. The present invention provides a release profile of flibanserin which is independent on the pH in the gastrointestinal tract when administered orally resulting in a significantly improved bioavailability.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: October 1, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Wolfram Eisenreich, Thomas Friedl
  • Patent number: 8535711
    Abstract: The potential for environmental release of unused and expired medications is reduced by the provision of a system and method for combining the unused or expired medication with an amount of activated carbon as part of a disposal procedure.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: September 17, 2013
    Assignee: Teikoku Pharma USA, Inc.
    Inventors: Carter R. Anderson, Russell L. Morris
  • Patent number: 8524759
    Abstract: An improved phenylbutazone carrier composition provides increased palatability to horses. Additionally, the composition improves the bioavailability of the phenylbutazone and thus increases the horse's blood plasma levels of the medicine for the same effective dosage of the medicine.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: September 3, 2013
    Inventor: Douglas J. Gordon
  • Patent number: 8506698
    Abstract: An oral composition comprising an active component and an adhesive film forming component comprising bleached shellac and shellac wax for the treatment of teeth.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: August 13, 2013
    Assignee: Colgate-Palmolive Company
    Inventors: Claude Blanvalet, Pierre Lambert, Viviane Tack
  • Patent number: 8486454
    Abstract: The present invention provides a method of attenuating the formation or reducing the severity of neurogenic pain in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic pain.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: July 16, 2013
    Assignee: Sessions Pharmaceuticals Inc.
    Inventors: Robert W. Sessions, Alan R. Kahn
  • Publication number: 20130171256
    Abstract: This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing venlafaxine or a pharmaceutically acceptable salt or solvate thereof. The dosage form has alcohol resistance and may also have crush resistance.
    Type: Application
    Filed: May 9, 2011
    Publication date: July 4, 2013
    Applicant: CIMA LABS Inc.
    Inventor: Ehab Hamed