Phosphate Compound Containing Patents (Class 424/57)
  • Patent number: 11903992
    Abstract: The present disclosure provides a composition comprising Lidocaine or salt or hydrate or solvate thereof, L-Carnosine or salt or hydrate or solvate thereof and dexpanthenol or salt or hydrate or solvate thereof. The composition may further comprise one or more other active agents. In an embodiment, the composition is formulated as an oral formulation. The compositions of the present disclosure may find utility in treatment of oral mucositis, ulcers, ulcer mediated pain and the like conditions. Aspects of the present disclosure also relates to method of treating oral, pharyngeal, oropharyngeal and esophageal diseases or conditions using the advantageous compositions of the present disclosure.
    Type: Grant
    Filed: February 10, 2022
    Date of Patent: February 20, 2024
    Assignee: Cellix Bio Private Limited
    Inventor: Mahesh Kandula
  • Patent number: 11883520
    Abstract: Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Said leave-on oral care compositions comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer and an additional polymer.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: January 30, 2024
    Assignee: The Procter & Gamble Company
    Inventors: Ross Strand, Yang Su, Yunming Shi, Thanigaivel Shanmugam, Guannan Wang, Xiaoxiao Li
  • Patent number: 11857558
    Abstract: This disclosure provides bioceramic compositions of multiparticulate crystalline multimetallic silicates having silica double tetrahedra structures, such as Strontium-akermanite (Sr2MgSi2O7), Akermanite (Ca2MgSi2O7), Baghdadite (Ca3ZrSi2O9), Hardystonite (Ca2ZnSi2O7), as sources for controlled release of multiple metallic ions, such as Ca2+, Mg2+, Zr4+, Sr2+, Zn2+ for medical and dental use. This disclosure also includes medical and dental uses of the disclosed compositions, for example, in tissue regeneration, including bone tissue.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: January 2, 2024
    Assignee: ANGELUS INDÚSTRIA DE PRODUTOS ODONTOLÓGICOS S/A
    Inventors: César Eduardo Bellinati, Cristiane Vila, William Pereira Dos Santos, Maíra Bendlin Calzavara
  • Patent number: 11826446
    Abstract: Disclosed are oral care compositions of phosphonate and sulfonate group containing polymer compositions that have targeted uses with divalent cations and surfaces having divalent cations. These compounds can be used to deliver anionic character to surfaces such as calcium hydroxyapatite.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: November 28, 2023
    Assignee: The Procter & Gamble Company
    Inventors: Ryan Michael West, Scott Leroy Cron, Yingkun Jin, William Michael Glandorf
  • Patent number: 11806416
    Abstract: This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of using and of making these compositions.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: November 7, 2023
    Assignee: Colgate-Palmolive Company
    Inventors: Lisa Manus, Julia Dreifus
  • Patent number: 11771733
    Abstract: Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and acute myocardial infarction.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: October 3, 2023
    Assignee: SILVERGATE PHARMACEUTICALS, INC.
    Inventors: Gerold L. Mosher, David W. Miles
  • Patent number: 11759405
    Abstract: Provided is an oral composition containing particles that have properties to seal dentinal tubules and excellent adhesion properties in dentinal tubules. Specifically, provided is an oral composition containing hydroxyapatite particles, wherein the hydroxyapatite particles have a ratio of a diffraction peak intensity around 2?=32° to a diffraction peak intensity around 2?=26° of 0.8 to 1.6 in an x-ray powder diffraction pattern as measured with CuK? characteristic X-rays.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: September 19, 2023
    Assignee: SUNSTAR SUISSE SA
    Inventors: Taku Ideue, Akihiko Komine, Ryotaro Nishioka, Shuhei Ishii
  • Patent number: 11723853
    Abstract: The invention relates to non-aqueous dentrfrice compositions comprising a surfactant system. The surfactant system consists of a combination of surfactants i.e. a betaine and a taurate surfactant; or a betaine and an alkyl sulphate surfactant; or a betaine, a taurate and an alkyl sulphate surfactant.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: August 15, 2023
    Assignee: BLOCK DRUG COMPANY INC.
    Inventor: John Hodgkinson
  • Patent number: 11497694
    Abstract: This application provides, among other things, novel aqueous monophasic compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: November 15, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Carl Myers, Guillaume Picquet, Ekta Makwana
  • Patent number: 11471388
    Abstract: An oral care composition with one or more polyphosphates with about 20 wt % or more of water at a pH of about 5 or less. A dentifrice composition with one or more polyphosphates with about 20 wt % or more of water at a pH of about 5 or less. A mouth rinse composition with one or more polyphosphates with about 20 wt % or more of water at a pH of about 5 or less.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: October 18, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Niranjan Ramji, Michael David Curtis, Samuel James St. John, Kathleen Pearson, Lina Aurora Witte, Andrea Noland
  • Patent number: 11413235
    Abstract: Described herein are liquid compositions, comprising an ethoxylated amine of a fatty acid, an organic solvent, and an acid.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: August 16, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Turan Matur, Sylvia Hess, Andre Brunella, Thomas Schollbach
  • Patent number: 11318078
    Abstract: A non-alcohol mouthwash composition includes a sweetener, a dispersing agent, a surfactant, an antimicrobial agent, a calcium ion source including calcium lactate, a phosphate ion source including monobasic sodium phosphate, a flavoring agent, a fluoride source, and water. The non-alcohol mouthwash composition includes about 0.001 weight percent of the calcium lactate and about 0.10 weight percent of the monobasic sodium phosphate, based on total weight percent of the non-alcohol mouthwash composition, and the composition has a pH greater than about 5.5.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: May 3, 2022
    Assignee: Fantarella & Harewood, LLC
    Inventors: Jeralyn R. Fantarella, Patrick Harewood
  • Patent number: 11274059
    Abstract: A dental formulation including: a bioactive glass composition as defined herein, in an effective amount; and a suitable carrier as defined herein, in an effective amount. Also disclosed is a method of making and using the dental formulation to treat, for example, dentin sensitivities.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: March 15, 2022
    Assignee: Corning Incorporated
    Inventors: Huayun Deng, Ye Fang, Qiang Fu, John Christopher Mauro, Michael S Pambianchi
  • Patent number: 11260004
    Abstract: An oral care composition, including a mixture of antibacterial agents, the mixture of antibacterial agents including oleanic acid and eugenol at a 2:1 to 3:1 weight ratio.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: March 1, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Shao Peng Xu, Dai Lin Chen, Neelima Utgikar
  • Patent number: 11213466
    Abstract: A personal care composition, comprising a soluble zinc polyphosphate complex made by combining ingredients comprising an inorganic zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and an aqueous solvent; wherein the relative amount of inorganic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Also, a method of using the composition for reducing at least one of perspiration or body odor.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: January 4, 2022
    Assignee: Colgate-Palmolive Company
    Inventors: Long Pan, Baohua Qiao
  • Patent number: 11135143
    Abstract: An oral care composition with a tin, polyol with five or six carbon atoms, polyol with seven or more hydroxyl functional groups, and a pH of greater than 7. An oral care composition with a tin ion source, a fluoride ion source, a polyol with five or six carbon atoms, a non reducing sugar or sugar alcohol with seven or more hydroxyl functional groups, and a pH of greater than 7. Oral care compositions with a high tin ion availability.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: October 5, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Shikhar Gupta, Guannan Wang, Ross Strand
  • Patent number: 11020330
    Abstract: A personal care composition, comprising a soluble zinc polyphosphate complex made by combining ingredients comprising an organic zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and an aqueous solvent; wherein the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Also, a method of using the composition for reducing at least one of perspiration or body odor.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: June 1, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Baohua Qiao, Peter R. Hilliard, Jr., Long Pan, Shiri Nawrocki, Viktor Dubovoy
  • Patent number: 10905638
    Abstract: A dentifrice composition comprises a toothpaste carrier having a pH of about 7 to about 10 and a calcium ion source and a fluoride ion source wherein the calcium ion source is unencapsulated and the fluoride ion source is encapsulated or coated in a coating impermeable to the toothpaste carrier. The coating degrades to release fluoride ions when mechanically agitated by a toothbrush in an oral cavity surface. In a second embodiment, the dentifrice composition comprises an aqueous toothpaste carrier having a pH of about 7 to about 10 with an unencapsulated calcium ion source and a fluoride ion source having a pH of between 3 to less than 7 wherein the fluoride ion source is encapsulated in a first (or inner) impermeable coating adapted to degrade to release the fluoride ions in the presence of a toothpaste carrier.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: February 2, 2021
    Assignee: BIODENTAL REMIN LTD.
    Inventors: Bjorn Kentaro Hilke, Alexander Ian McIntosh, Rosi Hilke
  • Patent number: 10881492
    Abstract: An oral care regimen where a user applies a first composition and a second composition to the oral cavity. The first composition can be a dentifrice and can contain stannous fluoride and the second composition can be a dentifrice and can contain hydrogen peroxide. The regimen can provide a long-lasting clean feeling. Compositions and methods for improving compliance with a two-part oral care regimen may include the use of a first composition with mildly unpleasant organoleptic properties.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: January 5, 2021
    Assignee: The Procter & Gamble Company
    Inventor: Paul Albert Sagel
  • Patent number: 10668005
    Abstract: An oral care composition and method for whitening teeth is disclosed. The oral care composition includes an orally acceptable vehicle, a blue dye and/or blue pigment having a blue to blue-violet color with a hue angle in the CIELAB system from about 200 to about 320 degrees, and a phosphate/acrylate copolymer.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: June 2, 2020
    Assignee: Colgate-Palmolive Company
    Inventors: Eric Simon, Venda Porter Maloney, Hallena Strotman
  • Patent number: 10561590
    Abstract: Disclosed herein are dentifrices comprising a zinc amino acid complex together with soluble phosphate salts. Methods of making and using the dentifrices are also provided.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: February 18, 2020
    Assignee: Colgate-Palmolive Company
    Inventors: Gregory Szewczyk, Lisa Manus, Lyndsay Schaeffer-Korbylo
  • Patent number: 10532016
    Abstract: Disclosed herein are zinc-amino acid-tripolyphosphate complexes, oral care and personal care compositions comprising zinc-amino acid-tripolyphosphate complexes, and methods of making and using the same.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: January 14, 2020
    Assignee: Colgate-Palmolive Company
    Inventors: Zhigang Hao, Dennis Zhang, Donghui Wu, Ravi Subramanyam, Chi-Yuan Cheng, Long Pan, Stanislav Jaracz
  • Patent number: 10314776
    Abstract: The present invention relates to the field of dental care, in particular, to a dental care product such as toothpaste (dentifrice), prophylactic paste, tooth powder, tooth polish, tooth gel, chewing gum, candy, lozenge, mouthwash, whitening strip, coated dental floss, coated toothbrush, paint-on gel, varnish, veneer, and tube, syringe or dental tray comprising a gel or paste, mouthwash, whitening strips and trays for whitening teeth, wherein the product comprises mineral particles such as crystals and a compound, preferably, a protein capable of forming a matrix which is a hydrogel, wherein the product comprises a fluorophore. The mineral particles may comprise, e.g., calcium phosphate, preferably, hydroxyapatite, preferably, in crystalline form. The protein matrix may comprise, e.g., a self-assembling peptide. The product also comprises a fluorophore, which may be a fluorescent amino acid residue of the protein matrix.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: June 11, 2019
    Assignee: Credentis AG
    Inventors: Michael Hug, Dominikus Amadeus Lysek, Karl-Heinz Kunzelmann
  • Patent number: 10285929
    Abstract: A composition for inhibiting enamel demineralization, promoting enamel remineralization and/or increasing salivary secretory immunoglobulin A is disclosed. The composition may contain lithothamnium calcareum (LC). The composition may comprise a first solution comprising at least 0.01% by weight LC and a second solution comprising an amount of hydrochloric acid (HCL) sufficient to adjust the pH of the composition to a physiological pH. A method of inhibiting enamel demineralization and promoting enamel remineralization is also disclosed. The method may include exposing a tooth to a LC containing composition. The method may further include both topically and systemically exposing the tooth to an LC containing composition. A method of increasing salivary secretory Immunoglobulin A (SIgA) in a mammal is also disclosed. The method may include topically exposing an oral cavity to a LC containing composition.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: May 14, 2019
    Assignee: PITTS AND BRETZ DEVELOPMENT PARTNERS
    Inventor: Walter A. Bretz
  • Patent number: 10238590
    Abstract: Described herein are compositions comprising an unactivated liquid, an immobilized sparingly soluble acid or base, such that during storage the unactivated liquid is not in contact with the immobilized sparingly soluble acid or base, but upon use, the unactivated liquid contacts the immobilized sparingly soluble acid or base, whereby the pH of the liquid is altered, thereby activating the liquid to provide a benefit; together with variant and alternative designs, methods of making and using the compositions, and components thereof.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: March 26, 2019
    Assignee: Colgate-Palmolive Company
    Inventors: Guofeng Xu, Steven Miller, Jennifer Gronlund
  • Patent number: 10231905
    Abstract: The present invention relates to providing a dental curable composition that, when cured, has high metal ion release ability and highly durable physical properties. The dental curable composition of the present invention includes: a sugar compound having an —XM group, where —X is an acid anion group and M is a metal cation; and a curable component.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: March 19, 2019
    Assignee: KURARAY NORITAKE DENTAL INC.
    Inventors: Mitsunobu Kawashima, Mitsuru Takei, Naoki Nishigaki, Shumei Ishihara, Kenji Hatanaka, Hiroshige Ishino, Akiko Tsuji
  • Patent number: 10130571
    Abstract: Disclosed herein are dentifrices comprising a zinc amino acid complex together with soluble phosphate salts. Methods of making and using the dentifrices are also provided.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: November 20, 2018
    Assignee: Colgate-Palmolive Company
    Inventors: Gregory Szewczyk, Lisa Manus, Lyndsay Schaeffer-Korbylo
  • Patent number: 10039698
    Abstract: An object of the present invention is to provide a tooth-cleaning composition having a high remineralizing effect on demineralized dental enamel. The tooth-cleaning composition contains a wax and a calcium phosphate, wherein a content of the calcium phosphate is 0.001 to 33% by mass.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: August 7, 2018
    Assignee: KABUSHIKI KAISHA SANGI
    Inventors: Takayuki Itakura, Rimiko Takikawa, Mariko Obuki, Rie Takamatsu
  • Patent number: 9623010
    Abstract: This invention relates to a an orally disintegrating tablet obtainable by direct compression of a dry powdered mixture, said mixture comprising up to 15% by weight of calcium silicate, at least 50% of a diluent, a disintegrant agent and an active ingredient. It also relates to a process for preparing the tablets by homogeneous blending the specific excipients in powder form and subsequent direct compression of the mixture. Said tablets disintegrate quickly in the cavity of the mouth, in particular in less than 15 seconds.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: April 18, 2017
    Assignee: LABORATORIOS LESVI, S.L.
    Inventors: Carmen Úbeda Pérez, Ignacio Díez Martín, Pablo Pablo Alba
  • Patent number: 9555269
    Abstract: The present invention is directed to a carrageenan product comprising a semi-refined, alkali treated iota carrageenan wherein the semi-refined, alkali treated iota carrageenan has: (i) a viscosity of 18 cP to 83 cP, (ii) a particle size of at least 90% passing through a #100 US sieve mesh and at least 20% passing through a #230 US sieve mesh, and (iii) a fraction of sodium cations of at least 35%, wherein the fraction of sodium cations is determined by the weight of sodium cations divided by the sum of the weight of sodium cations and potassium cations. This invention is also directed to toothpaste compositions comprising the carrageenan product of the invention.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: January 31, 2017
    Assignee: FMC Corporation
    Inventors: Christopher J. Sewall, Vinayak B. Randive, Vijay K. Gadkari
  • Patent number: 9468593
    Abstract: The present invention provides an oral composition comprising hydroxyapatite, potassium nitrate, and calcium monohydrogen phosphate, wherein the composition has an increased ability to occlude dentinal tubules of a tooth and has an excellent inhibitory effect on hypersensitivity.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: October 18, 2016
    Assignee: Kabushiki Kaisha Sangi
    Inventors: Tomoki Saito, Hiroyuki Kawamata, Kazushi Ota, Shuji Sakuma
  • Patent number: 9370475
    Abstract: Oral care compositions comprising isobutyl magnolol and n-butyl magnolol. A method of enhancing the solubility of isobutyl magnolol in an oral care composition comprises admixing n-butyl magnolol with an orally acceptable carrier comprising isobutyl magnolol. The composition may be used to treat diseases or conditions of the oral cavity such as caries, gingivitis, periodontitis, tooth yellowing and halitosis.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: June 21, 2016
    Assignee: Colgate-Palmolive Company
    Inventors: Lin Fei, Stanislav Jaracz, Ying Yang, Guofeng Xu
  • Patent number: 9301915
    Abstract: A protective coating material applied to whitened or bleached teeth. The protective coating material comprises microcrystalline wax, mineral oil, vitamin E, and amorphous calcium phosphate or ACP. The protective coating material covers the whitened or bleached tooth surface protecting it from staining thereby prolonging the whiteness of the teeth. The whitened or bleached damaged tooth enamel may also be strengthened or repaired.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: April 5, 2016
    Assignee: Centrix, Inc.
    Inventor: William B. Dragan
  • Patent number: 9205036
    Abstract: Aqueous homogeneous oral care compositions including a fluoride salt and unfunctionalized ?-tricalcium phosphate, characterized in that ?-tricalcium phosphate is present in a catalytic and fluoride-stable amount relative to the fluoride salt. Such compositions are of use in combating dental caries, dental erosion and/or tooth wear.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: December 8, 2015
    Inventor: Robert Karlinsey
  • Patent number: 9180319
    Abstract: A method of treating gum disease using a soft tissue diode laser which generates a beam of light having a wavelength in the visible portion of the electromagnetic spectrum (400 nm-700 nm) at a laser power of 0.5 to 1.2 watts, used with intermittent stops to control tissue temperature, to decontaminate the gum tissue and biostimulate the periodontium nonsurgically when used with a substrate, thus preventing the long junctional epithelium from migrating into the sulcus, preserving tissue height, and regenerating periodontium, the method comprising: placing the tip of the laser inside the sulcus; penetrating the entire sulcus by moving the laser light with intermittent stops to control tissue temperature vertically and horizontally throughout the sulcus; and placing a substrate in the sulcus prior to a blood clot forming, thus regenerating periodontium in the sulcus.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: November 10, 2015
    Inventor: Margaret V. Kalmeta
  • Patent number: 9140708
    Abstract: Described herein are methods for identifying a mammal having a heightened susceptibility to enamel erosion, together with kits therefor and uses and methods related thereto.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: September 22, 2015
    Assignee: Colgate-Palmolive Company
    Inventors: Lynette Zaidel, Steven Miller, Guy Carpenter, Gordon Proctor, David Bartlett, Rebecca Moazzez
  • Publication number: 20150147281
    Abstract: Provided are methods, test devices, and diagnostic kits for predicting, assessing, and diagnosing the risk of a disease using salivary analysis. The methods comprise providing a whole (unfractionated) saliva sample from a subject; contacting an aliquot of the saliva with two or more lectins under conditions that allow the two or more lectins to bind to a lectin-binding component of the saliva; detecting the amount of bound lectin; and comparing the amount of bound lectin to the amount known to bind a saliva sample from a control patient, to predict the risk of a disease in the subject. Also provided are methods for reducing the risk of a disease and a method for assessing the risk of the disease at a defined level.
    Type: Application
    Filed: November 17, 2014
    Publication date: May 28, 2015
    Inventors: Patricia A. Denny, Paul C. Denny, Mahvash Navazesh
  • Patent number: 9040025
    Abstract: This invention relates to a composition useful as a dentifrice comprising a surfactant agent consisting essentially of monoalkyl and dialkyl phosphate esters, wherein the ratio of monoesters to diesters is greater than 1, and optionally an abrasive agent consisting essentially of siliceous materials.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: May 26, 2015
    Assignee: RHODIA OPERATIONS
    Inventors: Robert Lee Reierson, Todd William Domke
  • Patent number: 9034301
    Abstract: It is intended to provide a remineralization promoter for tooth enamel and a composition for an oral cavity, which can highly effectively promote the remineralization of tooth enamel and strongly inhibit dental caries. The remineralization promoter for tooth enamel and the composition for an oral cavity are characterized by containing amorphous hydroxyapatite and/or amorphized hydroxyapatite showing two peaks at 2?=31 to 35° in X-ray diffraction. The amorphized hydroxyapatite is obtained by reacting calcium salt with phosphate in an aqueous solution and drying the reaction solution at a temperature of 10 to 70° C.
    Type: Grant
    Filed: April 8, 2008
    Date of Patent: May 19, 2015
    Assignee: KABUSHIKI KAISHA SANGI
    Inventors: Shuji Sakuma, Tsutomu Ishizaki, Tadayoshi Arakawa
  • Patent number: 9034308
    Abstract: This invention relates to a composition useful as a dentifrice comprising a surfactant agent consisting essentially of monoalkyl and dialkyl phosphate esters, wherein the ratio of monoesters to diesters is greater than 1, and optionally an abrasive agent consisting essentially of siliceous materials.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: May 19, 2015
    Assignee: RHODIA OPERATIONS
    Inventors: Robert Lee Reierson, Todd William Domke
  • Publication number: 20150132233
    Abstract: Compositions and methods for reducing oral sensitivity, increasing the systemic health of a mammal, occluding a dentinal tubule within a mammalian tooth, and/or depositing a precipitate on the surface of a mammalian tooth are provided, said compositions comprising theobromine (3,7-dimethylxanthine, the principal alkaloid in Theobroma cacao).
    Type: Application
    Filed: March 14, 2013
    Publication date: May 14, 2015
    Inventors: Arman Sadeghpour, Tetsuo Nakamoto
  • Patent number: 9023373
    Abstract: A dental remineralizing system, including a functionalized calcium-containing complex having an organic surfactant component mechanochemically attached to a distressed calcium phosphate component and blended with the comestible material.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: May 5, 2015
    Assignee: Indiana Nanotech
    Inventor: Robert L. Karlinsey
  • Patent number: 9011824
    Abstract: A dentifrice composition providing superior shine and polish, low RDA and effective whitening comprising a calcined aluminum oxide polishing agent, a water soluble condensed phosphate such as an alkali metal phosphate salt and an orally acceptable carrier or excipient is described. The composition is free of a silica abrasive.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: April 21, 2015
    Assignee: Glaxo Group Limited
    Inventors: Frank Lippert, Robert Anthony Lucas
  • Patent number: 9005587
    Abstract: The present invention provides compositions including saturated calcium phosphate (sCaP) solutions, that may be prepared from mixtures of calcium deficient apatite and one or more of sodium fluoride and zinc chloride, or F or Zn ions. The solutions may be prepared from mixtures of calcium compounds and one or more of sodium or potassium phosphates, sodium or potassium fluoride and zinc salts with, for instance, either phosphoric or hydrochloric acids. Such compositions may be useful for increasing occlusion of dentin tubules, decreasing bacterial attachment to dentin tubules, decreasing bacterial growth or colonization on tooth surfaces such as enamel and dentin surfaces including on dentin tubules, increasing resistance to acid dissolution, inhibiting dental caries formation and progression and tooth decay and inhibiting development of tooth hypersensitivity.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: April 14, 2015
    Assignee: New York University
    Inventors: Racquel Z. LeGeros, Haijing Gu, Dindo Mijares, Deepak Saxena, Sudharani Bodepudi
  • Publication number: 20150098911
    Abstract: Provided is an oral composition that can sufficiently remove protein staining present on a tooth surface, can effectively prevent adhesion of protein staining on a tooth surface and can provide a good actual feeling of the cleaning effect in the oral cavity. The oral composition comprises the following components (A) and (B): (A) an N-acylamino acid or a salt thereof in an amount of 0.005 mass % or more and 0.3 mass % or less; and (B) pyrophosphoric acid or a salt thereof in an amount of 0.005 mass % or more and 0.5 mass % or less, in which a mass ratio ((B)/(A)) of the component (B) to the component (A) is 0.05 or more and 40 or less and a total content of the component (A) and the component (B) is 0.01 mass % or more and 0.6 mass % or less.
    Type: Application
    Filed: June 7, 2013
    Publication date: April 9, 2015
    Applicant: Kao Corporation
    Inventors: Takuya Saito, Yoshitak Yano, Mika Nagayama, Misato Honda
  • Patent number: 8999298
    Abstract: A dental composition for oral use, containing a phosphorylated saccharide (a), a polyphosphoric acid and/or a salt thereof (b), and a cationic bactericidal agent (c), wherein a ratio of a total amount of the phosphorylated saccharide (a) and the polyphosphoric acid and/or a salt thereof (b) contained to an amount of the cationic bactericidal agent (c) contained, i.e. {(a)+(b)}/(c), is from 0.05 to 20 in a weight ratio.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: April 7, 2015
    Assignee: National University Corporation Okayama University
    Inventors: Yasuhiro Yoshida, Naoko Namba, Noriyuki Nagaoka, Shogo Takashiba, Kazuomi Suzuki, Yamato Nojiri, Hiroshige Ishino, Takahiro Sekiguchi, Koichi Okada
  • Publication number: 20150093339
    Abstract: The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the “umami” taste of monosodium glutamate) or sweet taste modifiers,—savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.
    Type: Application
    Filed: October 8, 2014
    Publication date: April 2, 2015
    Inventors: Catherine TACHDJIAN, Andrew P. PATRON, Sara L. ADAMSKI-WERNER, Farid BAKIR, Qing CHEN, Vincent DARMOHUSODO, Stephen Terrence HOBSON, Xiaodong LI, Ming QI, Daniel H. ROGERS, Marketa RINNOVA, Guy SERVANT, Xiao-Qing TANG, Mark ZOLLER, David WALLACE, Amy XING, Klaus GUBERNATOR
  • Patent number: 8992894
    Abstract: An oral stain remover which can remove a stain or a dental plaque effectively without a need of brushing the surface of teeth with a toothbrush or the like, and an oral composition containing the stain remover. An oral stain remover contains a salt of ultraphosphoric acid, and an oral composition contains the oral stain remover.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: March 31, 2015
    Assignees: Mandom Corporation, REGENETISS Inc.
    Inventors: Toshikazu Shiba, Atsushi Saitou, Kazuyoshi Okada, Yoshio Tsujino
  • Publication number: 20150086492
    Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1 of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) prior to dental care usage.
    Type: Application
    Filed: December 4, 2014
    Publication date: March 26, 2015
    Inventors: James R. Brown, Linh Fruge, Tao Xu, Michael Prencipe
  • Publication number: 20150086493
    Abstract: Disclosed is a non-aqueous oral care composition comprising an organoclay, carrier humectant and a calcium source. The non-aqueous oral care composition of the present invention is stable, has rheological characteristics of a hydrous oral care composition, and does not require a manufacturing step of heating and cooling.
    Type: Application
    Filed: March 20, 2013
    Publication date: March 26, 2015
    Inventors: Julie Savine Camille Guery, Edward George Pelan, Lin Wang, Weizheng Zhou