Phosphate Compound Containing Patents (Class 424/57)
  • Publication number: 20130017159
    Abstract: A dentifrice composition providing superior shine and polish, low RDA and effective whitening comprising a calcined aluminium oxide polishing agent, a water soluble condensed phosphate such as an alkali metal phosphate salt and an orally acceptable carrier or excipient is described. The composition is free of a silica abrasive.
    Type: Application
    Filed: March 29, 2011
    Publication date: January 17, 2013
    Inventors: Frank Lippert, Robert Anthony Lucas
  • Publication number: 20130017158
    Abstract: An oral care composition comprising a stannous ion source and/or a zinc ion source; a phytic acid or a phytic acid salt or mixtures thereof; characterised in that the phytic acid or phytic acid salt has an average IPn of greater than 5.2. In a composition which comprises stannous, there is a decrease in soluble stannous whilst maintaining an equivalent efficacy to a composition comprising a higher level of soluble stannous and efficacy is observed for avoiding stain and astringency problems. When zinc ions are present, it has been surprisingly found that a decrease in soluble zinc can provide an equivalent antimicrobial efficacy to a composition comprising a greater level of soluble zinc.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 17, 2013
    Inventors: Steven Hamilton HOKE II, Ross STRAND, Xiaoli WANG, Yiqun ZHANG
  • Publication number: 20130011345
    Abstract: The present invention has discovered that amide compounds represented by Formula I set forth below and isomers thereof have unexpected and advantageous flavor enhancement and modification properties: The amide compounds of the present invention can be used to enhance or modify the flavor of orally consumable compositions, such as foodstuff, chewing gums, dental and oral hygiene products, and medicinal products.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 10, 2013
    Inventors: Adam Jan Janczuk, Zhihua Liu
  • Publication number: 20120315228
    Abstract: A single-phase oral care composition is described. The composition comprises both calcium and phosphate sources and is substantially free of water and is substantially free of generated calcium phosphate comprising compounds. The single-phase oral care composition is stable, maintains good viscosity characteristics and avoids the need for compartmentalized packaging.
    Type: Application
    Filed: February 18, 2011
    Publication date: December 13, 2012
    Inventors: Yan Deng, Xiaoke Li, ZhiQing Zhang, GuoQing Zhao
  • Publication number: 20120315226
    Abstract: The present invention provides compositions including saturated calcium phosphate (sCaP) solutions, that may be prepared from mixtures of calcium deficient apatite and one or more of sodium fluoride and zinc chloride, or F or Zn ions. The solutions may be prepared from mixtures of calcium compounds and one or more of sodium or potassium phosphates, sodium or potassium fluoride and zinc salts with, for instance, either phosphoric or hydrochloric acids. Such compositions may be useful for increasing occlusion of dentin tubules, decreasing bacterial attachment to dentin tubules, decreasing bacterial growth or colonization on tooth surfaces such as enamel and dentin surfaces including on dentin tubules, increasing resistance to acid dissolution, inhibiting dental caries formation and progression and tooth decay and inhibiting development of tooth hypersensitivity.
    Type: Application
    Filed: March 29, 2012
    Publication date: December 13, 2012
    Inventors: Racquel Z. LeGeros, Haijing Gu, Dindo Mijares, Deepak Saxena, Sudharani Bodepudi
  • Publication number: 20120288454
    Abstract: The present invention relates to chemical industry for daily use field, specifically a dental protection toothpaste composition. Except toothpaste matrix components, the toothpaste composition including (the following components by weight of total composition): 0.48%-3.3% six tissue salts for homeopathy, 0.1%-9.8% Chinese herb medicine extractant, 0.08%-1.3% at least one of vitamin C vitamin E and coenzyme Q10. The toothpaste composition ingredient of the present invention connects the homeopathy medicine such as cell tissue salts, Chinese herb medicine and vitamin etc. active ingredients, which will help for solving tooth and oral health problems.
    Type: Application
    Filed: November 25, 2010
    Publication date: November 15, 2012
    Inventor: Wenzhong Zhao
  • Publication number: 20120282193
    Abstract: A composition for the prevention and treatment of initial tooth caries, that is composed of a phosphate-calcium gel with the Ca/P mass ratio ranging from 1.2 to 1.5 and with a bond energy of the 2p phosphorus electron of 131 eV to 136 eV and optionally containing at least one auxiliary dental substance. The composition can further contain an aqueous solution of methyl cellulose or/and chlorohexidine gluconate.
    Type: Application
    Filed: July 19, 2012
    Publication date: November 8, 2012
    Inventor: Martin MARYSKA
  • Patent number: 8303938
    Abstract: The present invention relates generally to an anti-calculus composition and method for treating subgingival calculus. The anti-calculus composition comprises a pyrophosphate and a tripolyphosphate in a pharmaceutically acceptable carrier. The composition may also comprise a fluoride providing compound.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: November 6, 2012
    Inventor: Douglas Andersen
  • Patent number: 8298516
    Abstract: The present invention relates generally to an anti-calculus composition and method for treating subgingival calculus. The anti-calculus composition comprises a pyrophosphate and a tripolyphosphate in a pharmaceutically acceptable carrier. The composition may also comprise a fluoride providing compound.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: October 30, 2012
    Inventor: Douglas Anderson
  • Patent number: 8293216
    Abstract: An oral care composition comprising a fused silica abrasive that offers improved cleaning.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: October 23, 2012
    Assignee: The Procter & Gamble Company
    Inventors: George Endel Deckner, Arif Ali Baig, Ellen Louise Colón, Iain Allan Hughes
  • Publication number: 20120258054
    Abstract: The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2, swishing the solution around and expelling the solution.
    Type: Application
    Filed: June 9, 2012
    Publication date: October 11, 2012
    Inventor: Brian Giles
  • Patent number: 8278368
    Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a caseinate. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a caseinate and a hardenable resin or a water-dispersible, polymeric film former are also provided.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: October 2, 2012
    Assignee: 3M Innnovatve Properties Company
    Inventors: Richard P. Rusin, Sumita B. Mitra, Kevin M. Cummings, Paul A. Burgio, Afshin Falsafi
  • Publication number: 20120244203
    Abstract: An oral composition includes high stain removal efficiency relative to its abrasive ability. The oral composition contains fused silica and a dental abrasive. The oral composition has a high stain removal ability relative to the abrasive ability thereof. In other words, the ratio (stain removal ability/abrasive ability) of the oral composition is high. Accordingly, the use of the oral composition makes it possible to efficiently remove stains without damaging the teeth more than necessary.
    Type: Application
    Filed: October 14, 2010
    Publication date: September 27, 2012
    Applicant: SUNSTAR INC.
    Inventor: Hiroshi Sakamoto
  • Publication number: 20120237458
    Abstract: Hydrogel particles include: (A) a water-insoluble complex containing catechins; (B) a compound which forms chelate together with divalent or trivalent metal ions; (C) a divalent or trivalent metal salt; (D) a gel-forming agent; and (E) water.
    Type: Application
    Filed: November 30, 2010
    Publication date: September 20, 2012
    Inventors: Yasuhiro Shidahara, Michiya Takagi, Kimikazu Fukuda, Susumu Nakatsu, Ikuhisa Ichimura, Tadayuki Tokunaga
  • Publication number: 20120231057
    Abstract: The present invention relates to methods and compositions for inhibiting, treating, and preventing dental diseases in human and non-human animals, particularly domesticated companion animals. More particularly, the present invention relates to the unexpected discovery that the combination of micron-sized particulate bioactive glass and a topical bisphosphonate yields a composition that is capable of treating and/or preventing dental problems such as periodontal disease, tooth decay and tooth resorption in animals, particularly small mammals such as cats.
    Type: Application
    Filed: March 12, 2012
    Publication date: September 13, 2012
    Inventor: Gary D. Hack
  • Patent number: 8263048
    Abstract: The invention is directed to a calcium phosphate complex and the composition containing the same for oral care applications, in which the calcium phosphate complex is formed by chelating the ?-polyglutamic acid (?-PGA) with amorphous calcium phosphate (ACP). This complex can prevent crystallization of ACP and maintain its high solubility. The calcium phosphate complex has superior mucoadhesion properties, allowing it to remain in the mouth longer and offering effective buffering, by which dental caries can be alleviated and prevented.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: September 11, 2012
    Assignee: Taipei Medical University
    Inventors: Jen-Chang Yang, Sheng-Yang Lee, Der-Zen Liu, Nai-Chia Teng, En-Sheng Ke, Chien Chung Chen, Dian-Yu Ji, Chen-Feng Ma, Hong-Da Wu
  • Patent number: 8263049
    Abstract: This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent.
    Type: Grant
    Filed: March 26, 2011
    Date of Patent: September 11, 2012
    Assignee: Rhodia Operations.
    Inventors: Tobias Johannes Fütterer, Lawrence Alan Hough, Robert Lee Reierson
  • Patent number: 8236286
    Abstract: The present invention relates to a liquid composition for the oral cavity, which contains the following components (A), (B), (C) and (D): (A) an oil-soluble flavor, (B) a cationic bactericide, (C) a sugar fatty acid ester, and (D) one or more compounds selected from the group consisting of polyglycerol fatty acid esters, polyoxyethylene hydrogenated castor oils, and sorbitan fatty acid esters. The present invention also pertains to a liquid composition for the oral cavity, which contains the following components (A), (B), (E) and (F): (A) an oil-soluble flavor, (B) a cationic bactericide, (E) a polyphosphoric acid or salt thereof, and (F) a polyglycerol fatty acid ester. The liquid composition for the oral cavity according to the present invention is excellent in the adsorption of the bactericide to teeth and the like, barely causes unpleasant odor, and is excellent in stability.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: August 7, 2012
    Assignee: Kao Corporation
    Inventors: Yoshitaka Yano, Shigeto Kayane, Takahisa Yamashiro
  • Patent number: 8221723
    Abstract: An oral care composition comprising an abrasive combination of a fused silica abrasive and other abrasive selected from the group consisting of precipitated silica, calcium carbonate, rice hull silica, silica gels, aluminas, aluminium silicates, water-insoluble phosphates including orthophosphates, polymetaphosphates, pyrophosphates, other inorganic particulates, and mixtures thereof.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: July 17, 2012
    Assignee: The Procter & Gamble Company
    Inventors: George Endel Deckner, Arif Ali Baig, Iain Allan Hughes
  • Patent number: 8221722
    Abstract: An oral care composition comprising a fused silica abrasive and an active.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: July 17, 2012
    Assignee: The Procter & Gamble Company
    Inventors: Arif Ali Baig, George Endel Deckner, Iain Allan Hughes
  • Patent number: 8216552
    Abstract: An oral care composition comprising a fused silica abrasive and a gel network.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: July 10, 2012
    Assignee: The Procter & Gamble Company
    Inventors: George Endel Deckner, Michael Jude LeBlanc, Lawrence Edward Dolan, Arif Ali Baig, Iain Allan Hughes
  • Patent number: 8211409
    Abstract: An oral care composition comprising fused silica and an oxidizing agent.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: July 3, 2012
    Assignee: The Procter & Gamble Company
    Inventors: Arif Ali Baig, George Endel Deckner, Iain Allan Hughes
  • Patent number: 8211406
    Abstract: An oral care composition comprising a fused silica abrasive and a stannous ion source.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: July 3, 2012
    Assignee: The Procter & Gamble Company
    Inventors: Arif Ali Baig, George Endel Deckner, Iain Allan Hughes, Erica Marie Kincaid
  • Patent number: 8211410
    Abstract: An oral care composition comprising a fused silica abrasive and a chelant.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: July 3, 2012
    Assignee: The Procter & Gamble Company
    Inventors: Arif Ali Baig, George Endel Deckner, Iain Allan Hughes, Erica Marie Kincaid
  • Patent number: 8197797
    Abstract: The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2, swishing the solution around and expelling the solution.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: June 12, 2012
    Assignee: Mineral Science Co.
    Inventor: Brian Giles
  • Publication number: 20120141588
    Abstract: An oral care composition includes an effective amount of a basic amino acid in free or salt form; and an effective amount of calcium silicate particles. The calcium silicate particles have an average diameter of less than about 5 microns, such that they can occlude dentinal tubules of the teeth. An oral care method includes applying the composition to an oral cavity of a subject to reduce or inhibit hypersensitivity of the teeth and to achieve other benefits.
    Type: Application
    Filed: December 7, 2010
    Publication date: June 7, 2012
    Applicant: Colgate-Palmolive Company
    Inventors: Suman Chopra, Rahul Patel, Lynette Anne Zaidel
  • Publication number: 20120134919
    Abstract: A method for formation of spherical particles of ion substituted calcium phosphate. The method is based on precipitation of particles from a buffered solution under static, stirring or hydrothermal conditions. Also, the use of the formed materials and the particles in itself.
    Type: Application
    Filed: August 4, 2010
    Publication date: May 31, 2012
    Applicant: BIOMATCELL AB
    Inventors: Hakan Engqvist, Wei Xia
  • Publication number: 20120129135
    Abstract: The invention provides an anion-containing calcium phosphate compound, composition and dental patch comprising the same and their use in remineralizing teeth. The anion-containing calcium phosphate compound has the following formula: (Ca+2)x(anion?a)y(PO4?3)z wherein 2x=(a*y+3z); a is an integer of 1 to 3; and each of x, y and z is not 0.
    Type: Application
    Filed: November 22, 2010
    Publication date: May 24, 2012
    Applicant: TAIPEI MEDICAL UNIVERSITY
    Inventors: JEN-CHANG Yang, Nai-Chia Teng, Chien-Chung Chen, Sheng-Yang Lee, Chen-Feng Ma, Dian-Yu Ji
  • Publication number: 20120121672
    Abstract: Oral care and other compositions comprising particles having cores attached to bioadhesive polymers for inhibition of pellicle formation, plaque formation, biofilm formation, biofouling, and microbial adhesion or attachment are described. Methods using said compositions to treat surfaces, such as oral surfaces.
    Type: Application
    Filed: January 26, 2012
    Publication date: May 17, 2012
    Applicant: Colgate-Palmolive Company
    Inventors: Davide Miksa, Harsh M. Trivedi, Tao Xu
  • Publication number: 20120114718
    Abstract: A method of repairing weakened teeth, including combining a first predetermined amount of an inorganic calcium source with a second predetermined amount of an organic material to define a mixture, placing the mixture in a milling vessel operationally connected to a planetary mill, introducing milling media into the milling vessel, milling the mixture to impart sufficient kinetic energy to break down the organic and inorganic materials into substantially smaller intermediate particles and fuse the intermediate particles together to yield functionalized molecules having both organic and inorganic chemical characteristics, combining a functionalized calcium phosphate/organic compound with a fluoridated formulation to define a hybrid system, and applying the hybrid system to the weakened teeth.
    Type: Application
    Filed: May 11, 2011
    Publication date: May 10, 2012
    Inventor: Robert L. Karlinsey
  • Patent number: 8163271
    Abstract: The present invention is directed towards a composition for highly efficient and quick plaque and tartar removal and inhibition including pure ascorbic acid crystals and/or granulars (vitamin C) and an enamel repairing composition such as hydroxyapatite. The composition can contain from about 10% up to 90% of ascorbic acid without compromising the tooth enamel because hydroxyapatite will repair any damage to the enamel. The composition can be used as dental powder, toothpaste, mouthwash, mouth spray and chewing gum in order to cover a wide range of consumers in different settings.
    Type: Grant
    Filed: March 1, 2006
    Date of Patent: April 24, 2012
    Assignee: Dentech, Inc.
    Inventors: Charles G. Leonhardt, John C. Busby
  • Publication number: 20120082628
    Abstract: Oral care compositions having improved taste, said compositions comprising: a carrier material; from about 0.001 to about 10%, by weight of the composition, of an oral care component selected from metal salts, antimicrobial agents, bad breath reduction agents, bleaching agents, surfactants, or a combination thereof; and from about 0.
    Type: Application
    Filed: September 29, 2011
    Publication date: April 5, 2012
    Inventors: John Christian Haught, Christine Marie Cahen, Koti Tatachar Sreekishna, Wenzhu Zhao, Yakang Lin, Cathy Renee Schinaman
  • Patent number: 8147807
    Abstract: A dental composition for oral use, containing a phosphorylated saccharide (a), a cationic bactericidal agent (b) and a solvent (c). By using the dental composition for oral use of the present invention, the adhesion of the bacteria in the oral cavity to the surfaces of the teeth can be suppressed for a long period of time; therefore, the dental composition for oral use can be suitably used for, for example, a mouse-wash agent, a dentifrice agent, a gargling agent, a mouse spray, a coating agent or a bonding agent to tooth surface or a dental prosthetic, a hypersensitive inhibitor, a therapeutic agent for periodontal diseases, that is applied to a periodontal pocket, or the like.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: April 3, 2012
    Assignees: National University Corporation Okayama University, Kuraray Medical Inc.
    Inventors: Yasuhiro Yoshida, Naoko Namba, Noriyuki Nagaoka, Kaori Yoshimoto, Shogo Takashiba, Kazuomi Suzuki, Hiroshige Ishino, Takahiro Sekiguchi, Koichi Okada
  • Publication number: 20120064017
    Abstract: A stabilized oral care composition comprising a borinic acid derivative, e.g., a borinic ester.
    Type: Application
    Filed: June 3, 2010
    Publication date: March 15, 2012
    Applicant: Colgate-Palmolive Company
    Inventors: Venda Porter, Andre Morgan, Stanislav Jaracz, Jennifer Gronlund, Guofeng Xu, Donghui Wu, Michael Prencipe, Ravi Subramanyam
  • Patent number: 8128911
    Abstract: An abrasive dentifrice composition which effects enhanced antiplaque and breath freshening properties which comprises an orally acceptable vehicle containing a combination of a safe and effective amount of an antibacterial agent and at least two enzyme ingredients.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: March 6, 2012
    Assignee: Colgate-Palmolive Company
    Inventors: Lori H. Szeles, Xiaoyan Liu, Malcolm Williams, M. Teresa R. Carale, Michael Prencipe, James G. Masters
  • Publication number: 20120052026
    Abstract: Antiplaque oral compositions are provided that contain an orally acceptable carrier and an antibacterial effective amount of the compound of formula (I). In various embodiments, the compositions contain from about 0.001% to about 10% by weight of the compound of formula (I).
    Type: Application
    Filed: November 9, 2011
    Publication date: March 1, 2012
    Applicant: COLGATE-PALMOLIVE COMPANY
    Inventors: Ravi Subramanyam, Prem Sreenivasan
  • Publication number: 20120042893
    Abstract: An oral care composition and method are described in which the composition includes a film or a plurality of film fragments entrained in a carrier. The film or plurality of film fragments comprises a zinc compound and the carrier comprises a polysaccharide and a maleic anhydride copolymer. The composition and methods provide benefits including one or more of increased consumer acceptability, improved solubility of zinc thus permitting the use of lower amounts of zinc compounds and reducing the adverse astringency associated with zinc, decreased adverse reactions brought about by the presence of zinc ions, enhanced aesthetics, improved stability for active or other functional materials, and controlled delivery of active materials such as zinc.
    Type: Application
    Filed: May 26, 2010
    Publication date: February 23, 2012
    Applicant: Colgate-Palmolive Company
    Inventors: Thomas S. Campbell, Thomas J. Boyd, Steven W. Fisher, Michael Prencipe
  • Publication number: 20120045402
    Abstract: Disclosed are dentifrice compositions comprising an orally acceptable vehicle and at least one source of metal ions in a polymer matrix, the metal being selected from zinc, stannous, copper or combinations thereof, the at least one source of metal ions comprising from 10 to 75 wt % of the total weight of the polymer matrix and the at least one source of metal ions, and wherein the dentifrice composition comprises less than 10 wt % water based on the total weight of the dentifrice composition. Also disclosed is a method of stabilizing at least one source of metal ions in a dentifrice compositions.
    Type: Application
    Filed: May 25, 2010
    Publication date: February 23, 2012
    Applicant: Colgate-Palmolive Company
    Inventors: Andre Morgan, Venda Porter, Melissa Martinetti, Michael Prencipe
  • Publication number: 20120039821
    Abstract: A liquid composition that is applied to teeth in advance of a whitening gel or paste. The liquid composition is preferably in a viscous gel form, such that when the composition is applied to teeth, it does not flow quickly off the teeth. The composition contains ne diluent; oxidizer; buffering agent; suspending agent; emollient; surface active agent; germicide; gelling agent; optionally one or more flavoring components selected from flavor stabilizers, sweeteners, and taste enhancers; and pH control agent.
    Type: Application
    Filed: August 15, 2011
    Publication date: February 16, 2012
    Applicant: ROBELL RESEARCH, INC.
    Inventors: Irwin Smigel, Lucia Smigel, Said Raziq
  • Publication number: 20120034280
    Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 5, 2011
    Publication date: February 9, 2012
    Applicant: Research Foundation of State University of New York
    Inventors: Marvin Cohen, Susanne Cohen, Bob Flynn
  • Publication number: 20120027829
    Abstract: A dentin mineralizing agent comprising tetracalcium phosphate particles (A) and an alkali metal salt of phosphoric acid (B), wherein the dentin mineralizing agent contains the tetracalcium phosphate particles (A) in an amount of 1 to 80 parts by weight relative to 100 parts by weight of the whole amount of the dentin mineralizing agent, and the blended amount of the alkali metal salt of phosphoric acid (B) relative to 100 parts by weight of the tetracalcium phosphate particles (A) is 1 to 100 parts by weight. Thus is provided a dentin mineralizing agent by which a dense HAp is formed on a dentin surface and HAp is deposited to a deep portion of a dentinal tubule, so that it can close the dentinal tubule.
    Type: Application
    Filed: March 26, 2010
    Publication date: February 2, 2012
    Applicant: Kuraray Medical Inc.
    Inventors: Tadashi Hashimoto, Mariko Sugiura, Shumei Ishihara, Mitsunobu Kawashima, Koichi Okada
  • Publication number: 20120021031
    Abstract: The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long-tem release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.
    Type: Application
    Filed: April 1, 2010
    Publication date: January 26, 2012
    Applicant: Colgate-Palmolive Company
    Inventors: Suman K. Chopra, Lynette Zaidel, Michael Prencipe
  • Publication number: 20120020901
    Abstract: The invention relates to desensitizing, anti-tartar oral care compositions comprising an orally acceptable vehicle and an effective desensitizing and anti-tartar amount of tetrapotassium pyrophosphate.
    Type: Application
    Filed: April 2, 2009
    Publication date: January 26, 2012
    Applicant: Colgate-Palmolive Company
    Inventor: Ben Gu
  • Publication number: 20120014883
    Abstract: Compositions containing one or more derivatives of essential oil compounds for use in personal care compositions, such as compositions for oral, throat and skin care are disclosed. These derivatives include acetals of parent essential oil aldehydes and ketones; esters or ethers of parent essential oil alcohols and phenolics; and esters of parent essential oil acids. Examples of parent essential oil aldehydes and ketones include citral, cinnamic aldehyde, ?-anisaldehyde, vanillin, ethyl vanillin, heliotropin, carvone, and menthone. Examples of parent essential oil alcohols and phenolics include thymol, eugenol, isoeugenol, dihydroeugenol, carvacrol, carveol, geraniol, nerol, vanillyl alcohol, heliotropyl alcohol, ?-anisyl alcohol, cinnamyl alcohol and ?-ionol. Examples of parent essential oil acids include ?-anisic acid, cinnamic acid, vanillic acid and geranic acid.
    Type: Application
    Filed: July 19, 2011
    Publication date: January 19, 2012
    Inventors: Douglas Craig Scott, Lowell Alan Sanker, Robert Leslie Swaine, JR.
  • Publication number: 20120003161
    Abstract: Inositol-tripyrophosphate is an allosteric effector of hemoglobin due to its ability to cross the plasma membrane of red blood cells and deliver oxygen to solid tumors, by lowering the oxygen affinity of the hemoglobin of red blood cells. The present invention is directed to the use of inositol-tripyrophosphate to reduce hemoglobin's affinity for oxygen in circulating red blood cells. The present invention is further directed to the use of inositol-tripyrophosphate to inhibit angiogenesis and enhance radiation sensitivity of hypoxic tumors. The present invention is further directed to the use of inositol-tripyrophosphate to enhance PO2 in hypoxic tumors.
    Type: Application
    Filed: August 18, 2011
    Publication date: January 5, 2012
    Applicant: NORMOXYS, INC.
    Inventors: Claude Nicolau, Ruth Greferath, Konstantina C. Fylaktakidou, Jean-Marie Lehn
  • Patent number: 8071077
    Abstract: Antiplaque oral compositions are provided that contain an orally acceptable carrier and an antibacterial effective amount of the compound of formula (I). In various embodiments, the compositions contain from about 0.001% to about 10% by weight of the compound of formula (I).
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: December 6, 2011
    Assignee: Colgate-Palmolive Company
    Inventors: Ravi Subramanyam, Prem Sreenivasan
  • Publication number: 20110280814
    Abstract: Processes for preparing an oral care composition having improved taste, color, odor and/or clarity, wherein said processes comprise the steps of: providing an unfiltered dentifrice component selected from unfiltered alkyl phosphate surfactants, alkyl phosphate ethoxylated surfactants, lauryl sulfate surfactants, betaine surfactants, antibacterial agents, cetyl pyridinium chloride, metal Salts, phytic acids, or mixtures thereof; filtering the unfiltered dentifrice component with an adsorbent to form a filtered dentifrice component; and incorporating the filtered dentifrice component into the oral care composition. In one such process, activated carbon with a median particle size of less than or equal to about 30 ?m, optionally a macro-mesoporous:microporous ratio about 0.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Inventors: John Christian Haught, Marc Alan Hester, Steven Hamilton Hoke, II
  • Publication number: 20110236442
    Abstract: A solid oral sensorial product includes at least one botanical material and at least one phosphate containing stain inhibitor. The botanical material is selected from the group consisting of tobacco, tea, coffee, cocoa, and combinations thereof.
    Type: Application
    Filed: March 26, 2010
    Publication date: September 29, 2011
    Applicant: Philip Morris USA Inc.
    Inventors: Donald E. Miser, William R. Sweeney, Qinglin Li, Jerome A. Merski
  • Publication number: 20110223119
    Abstract: The invention provides a composition capable of exerting an excellent whitening effect and imparting gloss to teeth. A method for removing a solid product formed on surfaces of teeth, the method containing applying an oral composition to teeth, wherein the oral composition contains 0.05 to 18% by weight of phytic acid or a salt thereof, and contains no polyvalent cation or contains a polyvalent cation in an amount of less than 0.1 fold mol relative to phytic acid, and wherein the oral composition, as diluted with water to 30% by weight, has a pH of 5.5 to 6.5.
    Type: Application
    Filed: October 23, 2009
    Publication date: September 15, 2011
    Inventors: Tsutomu Isobe, Yoshiyuki Eshita, Kazuhiko Kato, Masanobu Wakasa, Kenji Manago, Kuniyuki Nakanishi, Noriyuki Tanji
  • Publication number: 20110177012
    Abstract: This invention relates to a composition useful as an oral care composition comprising an organophosphate material, additional oral care composition ingredients, for example, a surfactant agent, and optionally an abrasive agent.
    Type: Application
    Filed: March 26, 2011
    Publication date: July 21, 2011
    Applicant: Rhodia Inc.
    Inventors: Tobias Johannes Fütterer, Lawrence Alan Hough, Robert Lee Reierson