Abstract: The present invention relates to multicomponent glasses and their use in powdered form as an additive in personal care products such as toothpastes.

Abstract: The present invention provides a phosphopeptide or phosphoprotein (PP) stabilised amorphous calcium phosphate or amorphous calcium fluoride phosphate complex having a calcium ion greater than about 30 moles of calcium per mole of PP.

Abstract: Disclosed herein is a pair of dry type patches for teeth whitening, having a patch for upper teeth and a patch for lower teeth, in which the patch for upper teeth has a shape different from the patch for lower teeth, and each patch has a controlled width and shape such that the contact area of each patch with gums is minimized. In the patch for upper teeth, a central portion covering right and left upper central incisors is widest. In the patch for lower teeth, either portion covering right and left lower canine teeth is widest. Since the dry type patches covers all the portions of the teeth while minimizing the contact area with gums, no or little irritation is caused and wearability is excellent.

Abstract: Processes for improving the taste of oral care raw materials using solvent extraction, said process comprising the steps of: providing a solid oral care raw material composition in need of treatment wherein said oral care raw material composition comprises an orally acceptable raw material and one or more undesirable non-polar materials; contacting said oral care raw material composition with an extraction solvent to form an extraction mixture comprising a solid phase and a solvent phase; and separating the solid phase from the extraction mixture; wherein the extraction solvent is selected from solvents having individual Hansen solubility parameters of a dispersion force component (?D) ranging from about 15 to about 17 (MPa)0.5, a polar component (?P) ranging from 0 to about 9 (MPa)0.5 and a hydrogen bonding component (?H) ranging from 0 to about 11 (MPa)0.5.

Abstract: Provided is an oral composition which is excellent in a gloss imparting effect on teeth. An oral composition, which comprises the following components (A) and (B): (A) 0.01 to 3% by mass of phytic acid or a salt thereof, and (B) 0.01 to 3% by mass of pyrophosphoric acid or a salt thereof, does not comprise a polyvalent cation or comprises a polyvalent cation in an amount of less than 0.1-fold mol relative to phytic acid, has pH 5.5 to 6.5 when diluted with water to 30% by mass, has the mass ratio (B/A) between the component (A) and the component (B) is 0.2 to 3.0, and does not comprise a fluoride or has the fluoride content of less than 500 ppm in terms of fluorine atoms.

Abstract: A method of whitening teeth, including an application of functionalized calcium phosphate additives generated via a solid-state method. The additives were produced by placing predetermined amounts of inorganic and inorganic materials and milling media into a vessel rotatably connected to a turntable platform, an amount of an organic material into the vessel, rotating the vessel in a first direction while turning the turntable platform in a second direction counter to the first direction, with the resultant material defining the functionalized calcium phosphate. The inorganic material may include calcium phosphates of varying phases, structure, and composition. The organic material may include anionic surfactants, cationic surfactants, neutral surfactants, carboxylic acids, polymers, copolymers, block copolymers, and combinations thereof. Once produced, the additives were added to comestibles, such as in confectionery and foodstuff formats, for delivery to the teeth and dental structures.

Abstract: An oral preparation of the present invention contains a multi-composition system including a calcium ion supplying compound; a fluoride ion supplying compound a polyolphosphate ion supplying compound; and, a monofluorophosphate ion supplying compound, wherein the calcium ion supplying compound and the fluoride ion supplying compound are separated within the oral preparation.

Abstract: The invention provides a composition capable of exerting an excellent whitening effect and imparting gloss to teeth. A method for removing a solid product formed on surfaces of teeth, the method containing applying an oral composition to teeth, wherein the oral composition contains 0.05 to 18% by weight of phytic acid or a salt thereof, and contains no polyvalent cation or contains a polyvalent cation in an amount of less than 0.1 fold mol relative to phytic acid, and wherein the oral composition, as diluted with water to 30% by weight, has a pH of 5.5 to 6.5.

Abstract: The present invention relates to an oral care composition and a method of disinfecting the oral cavity. So far synthetic material (e.g. Triclosan) has been used which is believed by many consumers to be harsh on them. Consumers, more and more prefer using products that contain natural materials. Further, in many countries, culturally or otherwise, people are reluctant to using alcohol in their mouthwashes. The present inventors have been working on solving these problems and have come up with an oral care composition which includes natural materials that are found to interact synergistically with certain metal salts in killing S. mutans, a bacterium responsible for tooth decay.

Abstract: Described herein are compositions comprising combinations of metal salts, and methods of preparing and using the same.

Abstract: A solid state method of encouraging the physical interfacing of an organic component to a substantially crystalline inorganic component, including adding predetermined amounts of a substantially crystalline inorganic precursor and a predetermined amount of an organic precursor to yield an admixture, maintaining the admixture in a substantially liquid-free environment, and impacting the precursors together with sufficient energy to fuse the precursors into hybrid compounds. The so-formed hybrid compounds substantially retain the long range crystalline order characteristics of the substantially crystalline inorganic precursor.

Abstract: Topical compositions containing from about 40% to about 77% by weight of the composition of a humectant component, said component containing from about 0.25% to about 7% of a structuring humectant selected from polyethylene glycols having an average molecular weight of from about 3,000 to about 8,000, and mixtures thereof; and at least one secondary humectant; the topical composition further comprises abrasive from about 5% to about 35%; from about 0% to about 1.5% of a viscosity modifier; a total solids content of 50% or less; water from about 5% to about 12%; and wherein the structuring humectant is added to the composition in solution with solvent or is added in a controlled manner as a molten material to the composition at a temperature less than about 35° C. and with turbulent mixing or vigorous agitation.

Abstract: A method of whitening teeth comprises the steps of contacting a stained tooth surface with an organic metal-ligand complex and an oxidizing compound, and exposing the stained tooth surface to actinic radiation.

Abstract: A one-component prescription fluoride treatment composition having both fluoride efficacy and sensitivity relief is disclosed. The composition includes at least one metal fluoride and a nerve desensitizing agent such as potassium nitrate. The invention further includes a composition having at least one metal fluoride less than about 1.15% by weight of at least one metal fluoride; less than about 5 percent by weight of at least one alkali metal salt having desensitizing effect; at least one carrier; and at least one foaming agent that has thickening property. The composition may be formulated into a gel, a paste or any other convenient form, some of which contain abrasives.

Abstract: Described herein are chewable articles intended to be provided to animals for purposes including dental cleaning, breath freshening, nutrition, administration to the animal of beneficial agents, satisfaction of the animal's urge to chew, and general enjoyment by the animal. The chews are made to be appetizing to the animal, to satisfy an urge to chew, to effect abrasive cleaning of the animal's teeth, to deliver one or more active agents to the oral cavity of the animal, or a combination of these. The chews have a resilient, chewable texture and are shaped to facilitate dental cleaning, to facilitate oral grasping by the animal, to appeal to human owners of the animal, to enhance the human-animal bond, or a combination of these. Also disclosed are apparatus and methods for making such chewable articles and for formulating and using them to effect dental health in animals.

Abstract: The present invention provides an oral cavity composition with which brief treatment using the same yields a high effect for dental cavity prevention and an excellent dental hyperesthesia preventive and treatment effects, and a method of treatment using such a composition. The oral cavity composition according to the present invention contains a first composition (A) containing a fluoride ion-supplying compound, an inorganic phosphoric acid and a salt thereof, and a second composition (B) containing a calcium salt of organic acid, with an organic acid constituting said calcium salt of organic acid having a pKa value ranging from 3 to 11, or at least one pKa value ranging from 3 to 11 when said organic acid has plural pKa values, wherein said first composition (A) and said second composition (B) are discretely packed from each other so that said two compositions can be alternately used and then come to be mixed with each other at a tooth region when applied thereto.

Abstract: A solid-state method of producing functionalized moieties, including placing predetermined amounts of inorganic and inorganic materials and milling media into a vessel rotatably connected to a turntable platform, an amount of an organic material into the vessel, rotating the vessel in a first direction while turning the turntable platform in a second direction counter to the first direction, milling the inorganic and organic materials into smaller respective organic and inorganic particles, and fusing portions of organic particles to inorganic parties to define functionalized moieties. The inorganic material may include calcium phosphates of varying phases, structure, and composition. The organic material may include anionic surfactants, cationic surfactants, neutral surfactants, carboxylic acids, polymers, copolymers, block copolymers, and combinations thereof.

Abstract: A oral care composition includes: (a) a hydrophilic film-forming polymer; and (b) a hydrophobic carrier, wherein the hydrophilic film-forming polymer is a film-forming polymer effective to occlude dentinal tubules and the oral care composition contains 0-10 wt. % water. The hydrophilic film-forming polymer is preferably GANTREZ S. The hydrophobic carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the hydrophilic film-forming polymer occludes dentinal tubules. A toothbrush includes: a handle; a head mounted to the handle, the head comprising an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.

Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.

Abstract: This invention relates to a dual phase mouthwash comprising a hydrophilic phase, a hydrophobic phase, and a hydrotrope, wherein the hydrophilic phase comprises an effective amount of a preservative selected from methylisothiazolinone, sodium benzoate, potassium sorbate, and combinations thereof, as well as to methods of using and of making such compositions.

Abstract: This invention relates to a mouthwash comprising an aqueous solution of an effective amount of an orally acceptable, soluble zinc salt together with an effective amount of a preservative selected from methylisothiazolinone (MIT), benzyl alcohol, glycerol monocaprylate, and combinations thereof; as well as to methods of using and of making such compositions.

Abstract: Pet food comprising trisodium L-ascorbic acid-2-monophosphate (STAY-C50) or sodium-calcium L-ascorbic acid-2monophosphate (STAY-C35), or mixtures thereof and, optionally, a polymer (for fixation of the ascorbate on the dental surface) and use 5 thereof as additive to pet food for preventing or treating calculus, plaque, gingivitis and periodontal disease and for enhancing the antioxidative capacity in the whole organism.

Abstract: An aqueous, heat and cold stable, non-alcoholic or slightly-alcoholic microemulsion based antimicrobial mouthwash composition with improved antimicrobial efficacy. The composition comprises a unique water-soluble matrix composite, at least one water-immiscible or water-insoluble antimicrobial agent, and optionally, a preservative or preservative system, a weak carboxylic acid, a coloring agent and other additives. Examples of antimicrobial agents include menthol, thymol, eucalyptol and/or methyl salicylate. A process for preparing the oral care composition is also disclosed.

Abstract: Oral products for the improved mineralization/remineralization of teeth are provided. In an embodiment, the present disclosure provides an oral product comprising a calcium salt, a phosphate salt, a sodium salt and a potassium salt. For example, the molar ratio of the sodium salt to the potassium salt ranges from about 3 to about 4.

Abstract: A teeth-whitening gel is provided. The main ingredient of the teeth-whitening gel comprises a polypeptide having halamine (N—X bond, X?Cl, Br or I) groups and a high molecular weight. By the redox properties of halamine group, the gel contacting with the teeth's surface can bleach and whiten the teeth.

Abstract: A dentifrice composition containing, in combination, an orally acceptable vehicle; a halogenated diphenyl ether; a soluble zinc salt; and a chelating agent to reduce astringency.

Abstract: Oral care compositions containing an oral care ingredient and a thickening agent, wherein the thickening agent comprises a strongly swellable, lightly to moderately crosslinked polyvinyl pyrrolidone. The polyvinyl pyrrolidone thickening agent is characterized by an aqueous gel volume of about 15 to 150 ml/g and a Brookfield viscosity of at least 10,000 cps for a 5% aqueous solution at 25° C.

Abstract: The present invention relates to the synthesis of bioceramics, in particular, of amorphous or cryptocrystalline calcium phosphates.

Abstract: A dentinal tubule sealant comprises poorly-soluble calcium phosphate particles (A), a phosphorus-free calcium compound (B), and water (C), wherein the particles (A) are at least one member selected from the group consisting of dicalcium phosphate anhydrous [CaHPO4] particles, ?-tricalcium phosphate [?-Ca3(PO4)2] particles, ?-tricalcium phosphate [?-Ca3(PO4)2] particles, amorphous calcium phosphate [Ca3(PO4)2.nH2O] particles, calcium pyrophosphate [Ca2P2O7] particles, calcium pyrophosphate dihydrate [Ca2P2O7.2H2O] particles, octacalcium phosphate pentahydrate [Ca8H2(PO4)6.5H2O] particles, and dicalcium phosphate dihydrate [CaHPO4.2H2O] particles, and the dentinal tubule sealant contains 30 to 76% by weight of the particles (A), 0.001 to 4% by weight of the compound (B), and 23 to 69% by weight of the water (C). Thus, there is provided a dentinal tubule sealant capable of sealing dentinal tubules of an exposed dentin and also remineralizing the surrounding dentin after the sealing.

Abstract: An dual oral composition is provided having a first peroxide-containing component and a second bicarbonate-containing component having exceptional anti-plaque and anti-bacterial action with re-mineralization properties.

Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.

Abstract: Oral care compositions with composite particle actives are described. The composite particle actives have a core and a coating whereby the coating interacts with phosphate ions to produce calcium and phosphate reaction products that are suitable to adhere to tooth enamel and/or dentin in order to improve the characteristics of teeth.

Abstract: The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2, swishing the solution around and expelling the solution.

Abstract: The invention relates to medicine, namely, to stomatology, in particular, to formulation for prophylaxis of oral cavity diseases. The formulation comprises: drinking water, glycerol, xylitol, silica, xanthan gum, methylparaben, propylparaben, titanium dioxide, perfume, bromelain, sodium saccharin, sodium lauryl sulfate or alkylamidobetain, calcium glycerophosphate, and magnesium chloride or glycerophosphate magnesium at following component ratio, % wt.: glycerol—20-25; xylitol—10-14; i 10 silica—22-26; xanthan gum—1.2-1.4; methylparaben—0.2-0.3; propylparaben—0.08-0.12; sodium saccharin—0.1-0.3; titanium dioxide—0.2-0.4; perfume—0.7-1.0; bromelain—0.1-0.7; sodium lauryl sulfate—1.2-1.4 or alkylamidobetain—1.2; calcium glycerophosphate—0.6-1.0; magnesium chloride—0.08-0.16 or magnesium glycerophosphate—0.16; and water—up to 100.

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a caseinate. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a caseinate and a hardenable resin or a water-dispersible, polymeric film former are also provided.

Abstract: Provided are compositions and methods for preventing dental caries, as well as aqueous compositions and methods for improving the mechanical strength of teeth.

Abstract: A delivery system for inclusion in an edible composition is formulated to have at least one active component with an encapsulating material for delivering the active component upon consumption of the edible composition wherein the dispersion of active component particles, as measured by the average distance between active component particles in the delivery system divided by the average particle diameter of the active component particles, is from 0.5 to 20.

Abstract: Described herein are dental compositions, articles of manufacture including such dental compositions, and methods of using such dental compositions. In some embodiments, the dental compositions include a combination of ascorbic acid with at least one of a hexametaphosphate and a beta glucans. In some instances, the dental compositions are included within an edible article, a chew, or an edible chew. Administration of the dental compositions to the oral cavity of a subject may reduce the gingival, plaque, and/or calculus scores of the subject over a defined time period.

Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors in skin cells that have not yet been damaged by ultraviolet radiation.

Abstract: An animal chew including a surface comprising a base composition, wherein the animal chew exhibits a hardness in the range of Shore 70A to Shore 70D as measured by ASTM D2240-05(2010) and a flexural modulus in the range of 50×103 psi to 500×103 psi as measured by ASTM D790-10 and Ascophyllum nodosum applied onto at least a portion of the surface of the animal chew, wherein the Ascophyllum nodosum is present in an amount of 0.1% by weight to 5.0% by weight of the animal chew. At least 10% by weight of the total amount of the Ascophyllum nodosum present in the animal chew may be applied to the animal chew surface.

Abstract: The invention provides a non-aqueous oral care composition with a liquid continuous phase comprising a thickening agent, a humectant, and one or more liquid polyethylene glycols having a melting point below 25° C., in which the liquid continuous phase is structured with crystals of one or more solid polyethylene glycols having a melting point of 25° C. or above. The rheological behaviour of the composition of the invention corresponds well with the characteristic rheological behaviour of typical aqueous dentifrice formulations.

Abstract: The present invention refers to compositions for the treatment or prophylaxis of infectious or inflammatory processes in the oral cavity (cavitas oris) including dental hygiene, the composition comprising lipoteichoic acids and glycerophosphate derivatives, preferably added into a dental hygiene product like toothpastes, toothgels, creams or rinsing fluids, the use of glycerophosphate derivatives as prophylaxis against bacterial infections of the oral cavity like dental caries, or the use of polyglycerophosphates for the production of a medicament for the treatment of or prophylaxis against bacterial infections of the oral cavity, like dental caries.

Abstract: Provided is a formulation for oral teeth, which includes a plurality of calcium ion carriers and a plurality of calcium-containing particulates. The particulates are carried by the calcium ion carriers, such that the formulation can prevent or rapidly treat dentin-associated symptoms or diseases, while providing a prolonged prophylactic or therapeutic effect.

Abstract: The present invention is directed towards a composition for highly efficient and quick plaque and tartar removal and inhibition including pure ascorbic acid crystals and/or granulars (vitamin C) and an enamel repairing composition such as hydroxyapatite. The composition can contain from about 10% up to 90% of ascorbic acid without compromising the tooth enamel because hydroxyapatite will repair any damage to the enamel. The composition can be used as dental powder, toothpaste, mouthwash, mouth spray and chewing gum in order to cover a wide range of consumers in different settings.

Abstract: Described herein are compositions which prevent the growth of bacteria resistant to high salt concentrations, methods of preparing the same, and methods of using the same.

Abstract: The present invention relates generally to an anti-calculus composition and method for treating subgingival calculus. The anti-calculus composition comprises a pyrophosphate and a tripolyphosphate in a pharmaceutically acceptable carrier. The composition may also comprise a fluoride providing compound.

Abstract: The present invention provides a solid, oral tooth whitening confectionary composition comprising a tooth whitening agent comprising an alkaline or alkaline earth metal pyrophosphate, preferably calcium pyrophosphate. In one embodiment, the composition of the invention comprises an additional tooth whitening agent.

Abstract: Treated surfactant composition containing a water-soluble surfactant and exhibiting improved taste, said composition comprising: a water-soluble surfactant selected from alkyl phosphate surfactants, alkyl phosphate ethoxylated surfactants, betaine surfactants, betaine ethoxylated surfactants, amine oxide surfactants, and mixtures thereof and water; wherein the composition further comprises: less than about 4%, by weight of the water-soluble surfactant, of total undesirable non-polar materials; less than about 2.5%, by weight of the water-soluble surfactant, of alcohols having a carbon chain length of greater than 4; less than about 1%, by weight of the water-soluble surfactant, of amine and amide materials; and less than about 1%, by weight of the water-soluble surfactant, undesirable non-polar materials selected from aldehydes, esters, ketones, and organic acids. Such compositions wherein the compositions have been subjected to liquid-liquid extraction processes.

Abstract: Processes for improving the taste of water-soluble surfactants using liquid-liquid solvent extraction, said process comprising the steps of: providing a water-soluble surfactant composition in need of treatment wherein said water-soluble surfactant composition comprises a water-soluble surfactant and one or more undesirable non-polar materials; contacting said water-soluble surfactant composition with an extraction solvent and water to form an extraction mixture comprising an aqueous phase and a solvent phase; and separating the aqueous phase from the solvent phase; wherein the extraction solvent is selected from solvents having individual Hansen solubility parameters of a dispersion force component (?D) ranging from about 15 to about 17 (MPa)0.5, a polar component (?P) ranging from 0 to about 9 (MPa)0.5 and a hydrogen bonding component (?H) ranging from 0 to about 11 (MPa)0.5.

Abstract: A formulation for an oral care application comprises a linear polyphosphate or a polyphosphate blend having a short average effective chain length. The polyphosphate blend may further comprise a cyclic phosphate and a linear polyphosphate. The formulation provides whitening effects, decreased tooth sensitivity, strengthened tooth enamel, and remineralization. The present invention further relates to methods for making an oral care formulation comprising a linear polyphosphate or a polyphosphate blend having a short average effective chain length. Methods of applying an oral care formulation comprising a linear polyphosphate or a polyphosphate blend having a short average effective chain length are also disclosed.