Abstract: An antibacterial composition having a heat-resistant property sufficient for avoiding its decomposition or discoloration at the resin molding temperature comprises; a silver thiosulfate complex salt carried on silica gel particles having an equilibrium water content of 10% or smaller, wherein at least part of the surface of the silica gel particles carrying said silver thiosulfate complex salt is covered with a coating layer composed of silicon dioxide formed by means of hydrolysis of an alkoxysilane.

Abstract: An antibacterial ceramic contains an antibacterial material produced by loading an antibacterial metal such as silver on a calcium ceramic carrier and an inorganic material such as cordierite, and has a bulk density of 0.6-1.2 g/cm.sup.3. An antibacterial ceramic filter contains an antibacterial material produced by loading an antibacterial metal such as silver on a calcium ceramic carrier, an aggregate such as mullite, and a binder such as frit, and has a porosity of 20% or more. The light-weight antibacterial ceramic is suitably applicable to a roof garden or the like. The antibacterial ceramic filter can remove and extirpate various bacteria and suspensions.

Abstract: Antimicrobial metal-based compositions, which are photostable, non-staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest," wherein stabilization of this "host-guest relationship" is accomplished through the use of excess anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices, foams and adhesives to impart infection-resistance.

Abstract: An antimicrobial composition comprising an inorganic particle with a first coating providing antimicrobial properties and a second coating providing a protective function is disclosed with a method for preparing the same and uses; further processes for producing polymeric articles and a method for controlling microorganisms are also disclosed.

Abstract: The present invention relates to cosmetic preparations containing finely divided, solid particles of gold, silver or platinum.

Abstract: Biowaste treatment agents for treating biowastes in a manner which: (a) keeps noxious and toxic substances from being released from the biowaste, and (b) neutralizes such substances released during the course of stabilizing the biowaste. The treatment agents include a surfactant in an amount of from 1.0 to 99 percent of the treatment agent, a metal component in an amount from 0.5 to 85 percent of the treatment agent, the metal component including a source of zinc, or copper, or a combination of copper with aluminum or iron, and an aldehyde in an amount from 0.1 to 80 percent of the treatment agent.

Abstract: The employment of molecular crystals as bactericidal, viricidal and algicidal devices, and specifically the molecular semiconductor crystal tetrasilver tetroxide Ag.sub.4 O.sub.4 which has two trivalent and two monovalent silver atoms per molecule, and which through this structural configuration generates electronic activity on a molecular scale capable of killing algae and bacteria via the same mechanism as macroscale electron generators.

Abstract: An antiviral composition comprising: a thiosulfate salt and at least one of thiosulfate complex salt of a metal and a porous particulate carrier; said metal being at least one selected from the group consisting of silver, copper and zinc; said salts being carried on said porous particulate carrier. It is applicable to a wide range of living environment such as medical instruments and appliances, hygienic implements as well as kitchen utensils, and also demonstrates an antibacterial activity in addition to the antiviral activity. The composition releases its salts slowly to the environment and the antiviral and antibacterial activities of said composition lasts for a long period of time. A method for preparing said composition as well as an antiviral disinfection method and a virucidal disinfection fluid using said composition are also disclosed.

Abstract: An antibacterial and antifungal composition which comprises an antibacterial and antifungal material carried on a porous particle carrier is provided. Preferably, the porous particle carrier is a silica gel particle. The antibacterial and antifungal material is at least one metal complex salt, and can contain plant extracts and the like in addition to the metal complex salt. At least a portion of the surface of the above-mentioned carrier having the antibacterial and antifungal composition can be coated with a coating material.

Abstract: An antimicrobial composition of titanium dioxide, barium sulfate, zinc oxide particles, and mixtures thereof having successive coatings of silver, in some cases a coating of zinc and/or copper compounds such as zinc oxide, copper (II) oxide and zinc silicate; silicon dioxide; alumina; and a dispersion aid such as dioctyl azelate.

Abstract: Antibacterial and antifungal polyacetal resin compositions include a polyacetal base resin, and an antibacterial and/or antifungal effective amount between about 0.1 to about 5 parts by weight, per 100 parts by weight of the polyacetal base resin, of at least one antibacterial and antifungal agent which contains a metal ion selected from among silver, copper and zinc ions.

Abstract: A medicinal substance for topical application is disclosed. The substance comprises a water-soluble glass containing silver or a silver compound. Typically, the glass comprises phosphorus pentoxide and contains silver oxide. The substance may be used for the treatment of wounds, catheter and tubing entry points, stoma sites and body passage entrances where bacterial growth and migration are rife. The glass may be in the form of a powder, granules, woven into a dressing form, a sinter shaped in a particular way or used as filler in polymers for surface release.

Abstract: A dentifrice (tooth paste) having an antibacterial effect to prevent production of carious tooth and generation of periodontal diseases such as alveolar blennorrhea. The dentifrice contains hydroxylapatite powder. The hydroxylapatite powder carries therein an antibacterial metal such as silver, copper and/or zinc. The antibacterial metal is adsorbed to and/or combined, under ion exchange, with the hydroxylapatite powder.

Abstract: A composition is provided for treating drinking water for disinfecting and/or removing iodide. The composition utilizes resin bound silver ions. For performing the disinfection or iodide removal with minimal release of silver ions into the water being treated, a chelating resin having iminodiacetate chelating groups is employed, and the resin is loaded with not over 0.5 mol of silver ions per mol of iminodiacetate.

Abstract: The growth of algae, fungi and pathogenic organisms in commercial and recreational waters, such as cooling towers, swimming pools and spas, may be controlled by adding to the water a primary sanitizing agent, preferably poly(hexamethylene biguanide) ("PHMB"), and a potentiating adjuvant comprising a calcium ion-chelating agent, preferably ethylenediamine tetraacetic acid ("EDTA"), in amounts such that the adjuvant renders the composition algicidal and fungicidal in water. The water may be further treated with a peroxy salt as a backup agent, preferably sodium perborate, or the calcium ion-chelating agent and peroxy salt may be combined as a shock treatment to water being treated with the primary sanitizing agent.

Abstract: The present application is directed to oral hygiene agents, a process for their preparation, and the use of a hydrogen peroxide solution stabilized by a silver colloid in concentrations of from 0.1 to 10% by weight, preferably from 1 to 3% by weight, in oral hygiene agents.

Abstract: An antimicrobial composition for topical use or for incorporation into a coating or structural composition comprises an antimicrobial silver compound, preferably silver chloride, deposited on a physiologically inert oxidic synthetic particulate support material. A preferred support material is titania containing one or more of the crystalline forms anatase, rutile, and brookite.

Abstract: The invention provides a novel antibacterial compound and a process for producing it. Futhermore, the invention provides a novel antibacterial polymer composite comprising a polymer and the antimicrobial compositon.

Abstract: A process for producing an antimicrobial fiber having a silver-containing inorganic microbicide characterized by using a treating solution for producing said fiber which contains a discoloration inhibitor represented by the following general formula: ##STR1## wherein R.sup.1 is hydrogen or a lower alkyl group and R.sup.2 is hydrogen or an alkali metal.

Abstract: Topical compositions for use in the treatment of burns and other infection-prone wounds and of ocular infection are provided. These compositions comprise silver or a silver salt, an antibiotic selected from among aminoglycoside antibiotics and quinolone antibiotics, with the proviso that the antibiotic is not norfloxacin; and a sterile carrier, such as water or an ointment base.

Abstract: Ferritin analogs comprising an apoferritin protein shell and a core substantially devoid of ferrihydrite, e.g. of inorganic composition such as aluminum hydroxide or organic composition such as acetaminophen. The protein shell can be removed from ferritin analog to produce spherules having a substantially monomodal nominal diameter between about 45 and 90 Angstroms.

Abstract: A calcium tertiary phosphate is used as a carrier, and the carrier is caused to carry silver and zinc. The result is an antibacterial ceramic exhibiting an ultra high degree of whiteness and suppressed discoloration. This material may be heat fired at a temperature above 960.degree. C. to obtain a further improvement.

Abstract: A novel molecular scale device is described which is bactericidal, fungicidal, viricidal and algicidal. The anti-pathogenic properties of the device are attributed to electron activity indigenous to diamagnetic semiconducting crystals of tetrasilver tetroxide (Ag.sub.4 O.sub.4) which contains two monovalent and two trivalent silver ions in each molecular crystal. When the crystals are activated with an oxidizing agent, they release electrons equivalent to 6.4.times.10.sup.-19 watts per molecule which in effect electrocute pathogens. A multitude of these devices are effective at such low concentrations as 0.3 PPM used as preservatives in a variety of formulations ranging from cosmetics to pharmaceuticals. Indeed, they are intended as active ingredients for pharmaceuticals formulated to destroy such pathogens as Staphylococcus aureus, and epidermidis, the latter of which it completely destroys in a nutrient broth culture of about 1 million organisms at 0.

Abstract: A pharmaceutical composition comprising at least one active ingredient, a carrier substance and a preservative dissolved in the carrier substance, the preservative comprising sodium silver chloride compound, is disclosed.

Abstract: A water-soluble glass treating agent consisting essentially of, by weight: 55 to 80% of SiO.sub.2, 19.5 to 42% of Na.sub.2 O and 0.5 to 3% of Ag.sub.2 O (conversion for AgNO.sub.3) is disclosed. Also disclosed is a water-soluble glass treating agent further containing, by weight: 0.5 to 30% of Al.sub.2 O.sub.3 in the above compositions. These glass water treating agents are glass free from boron constituent but which functions to kill or suppress bacteria and micro-organisms and are low in cost because it is simple in the composition of glass which is composed principally of three constituents at max. That agent which contains Al.sub.2 O.sub.3 functions to increase concentration of Ag in glass and to decrease the deliquescent property of glass.

Abstract: Antimicrobial metal-based compositions, which are photostable, non-staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest," wherein stabilization of this "host-guest relationship" is accomplished through the use of excess halide anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices and adhesives to impart infection-resistance.

Abstract: Disclosed is an agent for preventing the adhesion of water borne organisms, in which a calcium phosphate-based compound is made to carry, by adsorption and/or ion exchange, preferably not more than 15% by weight of at least one metal or metal ion selected from the group consisting of silver, copper, zinc and nickel. Also disclosed is a paint in which 0.1%-30% by weight of this agent is mixed.

Abstract: A method for improving the antibacterial efficacy of an ophthalmic solution, particularly a solution for the care of contact lenses, comprises providing an article molded from a plastic resin including an inorganic carrier retaining antibacterial metal ions, and placing the ophthalmic solution in contact with the plastic resin.

Abstract: The present invention provides a microbicide which comprises a phosphate represented by the following general formula:M.sub.a.sup.1 A.sub.b M.sub.c.sup.2 (PO.sub.4).sub.d.nH.sub.2 Owherein M.sup.1 represents at least one element selected from the group consisting of silver, copper, zinc, tin, mercury, lead, iron, cobalt, nickel, manganese, arsenic, antimony, bismuth, barium, cadmium and chromium, M.sup.2 represents at least one element selected from tetravelent metal elements, A represents at least one ion selected from the group consisting of hydrogen ion, alkali metal ions, alkaline earth metal ions and ammonium ion, n represents a number which satisfies 0.ltoreq.n.ltoreq.6, a and b each represents a positive number and satisfy la+mb=1 or la+mb=2, and when a and b satisfy la+mb=1, c is 2 and d is 3, and when a and b satisfy la+mb=2, c is 1 and d is 2, where 1 is valence of M.sup.1 and m is valence of A.

Abstract: A cosmetic product is provided which comprises particles of soluble glass having an average particle size of 20 .mu.m or less which contains silver ions. The soluble glass has a rate of elusion of the silver ions in water of from 0.00001-50 mg per hour per gram of glass when the soluble glass has a particle size of 420-600 .mu.m and the water has a temperature of 20.degree. C. The silver ions provide an anti-bacterial and anti-mold effect for a prolonged period without skin irritation, thus insuring a high degree of safety.

Abstract: A calcium phosphate ceramic such as hydroxyapatite or calcium tertiary phosphate or calcium carbonate is used as a carrier, and the carrier is caused to carry silicon in addition to silver, or silicon and zinc in addition to silver. The result is an antibacterial ceramic exhibiting an ultra high degree of whiteness and suppressed discoloration. This ceramic material may be heat-fired at a temperature above 960.degree. C. to obtain a further improvement.

Abstract: A method of producing zeolite particles with reduced carbonate species so that the zeolite particles are ion exchangeable with biocidal metal ions.

Abstract: The invention related generally to the preparation of colloidal metal(O) particles having a crosslinked aminodextran coating with pendent amine groups attached thereto. The aminodextran acts as both a reductant for reducing metal ions to metal(O) particles and as the protective agent which coats the metal(O) particles thus formed. After stabilizing the aminodextran coating by use of a crosslinking agent, the coated particles can be used to covalently bind proteins. The resulting protein containing colloidal particles can be used as markers in optical and electron microscopy, in immunological and biological assays, and possibly as therapeutic agents.

Abstract: The present invention provides a novel antimicrobial composition and a process for preparing the composition which composition is useful as antimicrobial and/or bactericidal material. The antimicrobial composition of the invention comprises silica gel and an antimicrobial coat of aluminosilicate on the surface of the silica gel, said composition having a pore volume of at least 0.3 cm.sup.3 /g and a specific surface area of at least 100 m.sup.2 /g. The aluminosilicate coat consists of either partial or complete substitution of ion-exchangeable metal ion (M) in aluminosilicate solid particles represented by the formulaxM.sub.2/n O.Al.sub.2 O.sub.3.ySiO.sub.2.zH.sub.2 O,wherein x and y represent the numbers of molecules of the metal oxide and silicon dioxide, respectively, M is an ion-exchangeable metal, n is the atomic valence of M, and z is the number of molecules of water.

Abstract: A method for controlling the growth of bacteria and algae in utilitarian bodies of water such as industrial cooling towers, swimming pools and hot tubs is described. The method comprises adding to the water novel trivalent silver compounds. Said compounds are light stable and can be supplied as liquid concentrates which will not precipitate any silver whatsoever from saline waters nor will the concentrates stain skin or discolor surfaces. Said compounds meet the rigid EPA standards of killing 100% of select coliforms within ten minutes and are efficacious at concentrations as low as 1-2 PPM.

Abstract: A water disinfection system is disclosed. The system comprises a permanganate in a concentration of up to about 15 mg/L, copper ions in a concentration of up to about 900 .mu.g/L, and silver ions in a concentration of up to about 90 .mu.g/L. In addition, a method for disinfecting water utilizing this system is described.

Abstract: A novel molecular scale device is described which is bactericidal, fungicidal and algicidal. The antipathogenic properties of the device are attributed to electron activity indigenous to diamagnetic semiconducting crystals of tetrasilver tetroxide (Ag.sub.4 O.sub.4) which contains two monovalent and two trivalent silver ions in each molecular crystal. When the crystals are activated with an oxidizing agent, they release electrons equivalent to 6.4.times.10.sup.-19 watts per molecule which in effect electrocute pathogens. A multitude of these devices are effective at such low concentrations as 0.3 PPM where they can kill 100% of 100 K/cc Streptococcus faecalis, and E. coli colonies in three minutes meeting the ten-minute EPA criteria of 100% kills within ten minutes for swimming pool and hot-tub applications. The devices can be used in utilitarian bodies of water, such as municipal and industrial water reservoirs.

Abstract: An antibacterial ceramic material wherein at least one ceramic selected from the group consisting of hydroxyapatite, calcium phosphate, calcium hydrogen phosphate, calcium carbonate, calcium silicate and zeolite is made to absorb and tightly retain at least one liquified metal salt selected from the group consisting of salts of silver, copper and zinc, after which heat firing at elevated temperatures is performed.

Abstract: An antibiotic formulation useful in the treatment of burns and abrasions and adapted for topical application as a clinically water soluble foam, the process for preparing the formulation and a special dispenser system for applying same.

Abstract: An antismoke mouthwash comprising silver nitrate and propylene glycol in water, a process for preparing said mouthwash and a method of using the mouthwash to help a smoker quit smoking.

Abstract: A method for producing an antibacterial molded article of polyolefin resin is described, comprising molding a polyolefin resin composition having compounded therewith 0.01% by weight or more, based on the polyolefin resin composition, of an antibacterial agent which is a zeolite containing silver to form a molded article of a desired shape, and thereafter subjecting the antibacterial surface of the molded article to a corona discharge treatment.

Abstract: Solid bactericidal compositions are disclosed based on divalent silver (Ag(II)) as the active sanitized agent. The compositions are prepared by reacting acid liquid Ag(II) complexes with anhydrous calcium sulfate so as to form a solid matrix in which the bactericide is entrapped in the resulting hydrated calcium sulfate. Optimum compositions are described consisting of Ag(II) phosphate dissolved in phosphoric acid where the ratio of solid (by weight) to liquid (by volume) is 5:2. The resulting solid bactericides can be used in water cooling installations. They are capable of causing 100% kills within 10 minutes of E. Coli conforms in conformity with EPA protocols, allowing them to quality as swimming pool and hot tub sanitizers. Since the compositions are based on calcium sulfate, they are also suitable as mineralizers, thus providing a dual function.

Abstract: Divalent silver halides provide a source for divalent bactericidal silver ions in the presence of persulfate. The halides are especially effective when applied to water used in industrial cooling installations, hot tubs and swimming pools and will conform to stringent EPA requirements for waters utilized for bathing as in tubs and pools of 100% kills of 100 K/cc E. Coli coliforms within 10 minutes, exemplary of which are the chloride and bromide which give 100% kills within 5 minutes. The halides, of course, can be used in salty water since they are solids immune from halide action that would otherwise precipitate soluble divalent silver from solution.

Abstract: Solid alkaline bactericidal compositions are disclosed suitable for compounding alkaline end products such as food and dairy cleaners and surgical scrubbing soaps, formed by the neutralization of acid stabilized inorganic divalent silver complexes and capable of effecting 100% kills upon cultures of anaerobic bacteria colonies of 100K/cc. within 5 minutes.

Abstract: A method or methods of controlling the growth of bacteria in the water of swimming pools and/or industrial water supplies by adding to the water a specified concentration of a stable divalent silver compound. The invention has the advantage over chlorination in that it is odorless and non-volatile. It furthermore is superior to monovalent silver compounds as these compounds do not decompose in the presence of light and resist precipitation by halides and form divalent soluble complexes which in the monovalent state are invariably insoluble solids.

Abstract: Antimicrobial hydroxyapatite powders containing hydroxyapatite powder and metal ions selected from silver, copper and zinc ions or one or more antimicrobial agents selected from hinokitiol, tannin, lysozyme, protamine and sorbic acid.

Abstract: An inexpensive, easily available and convenient method of inhibiting the transmission of the AIDS virus in humans as a result of sexual intercourse is provided. The method relies upon a dual mode of action of antiviral compositions comprising silver salts, such as silver sulfadiazine, alone or in combination with chlorhexidine or sodium deoxycholate. These composition are effective to reduce the infectivity of the AIDS virus and also kill the causative organisms of many other sexually transmitted diseases (STD). The method of the invention is therefore useful to reduce the immediate risk of AIDS transmission. It also reduces future risk of AIDS transmission by eliminating STD causing organisms which increase the risk of AIDS.

Abstract: An antibiotic zeolite and an antibiotic resin composition containing thereof are provided. The antibiotic zeolite is prepared by replacing all or a part of ion-exchangeable ions in zeolite with ammonium ions and antibiotic metal ions such as silver, copper, zinc, mercury, tin, lead, bismuth, cadmium, chromium and thallium. The antibiotic resin composition comprises the antibiotic zeolite and a resin such as polyethylene, polypropylene, polyvinyl chloride and polystyrene.

Abstract: An antibiotic resin composition comprises at least one antibiotic zeolite of which ion-exchangeable ions are partially or completely replaced with ammonium ionsand antibiotic metal ions, at least one discoloration inhibitor and at least one resin. The antibiotic resin composition exhibits excellent antibiotic property and does not discolor with time. Thus, the resin composition can be employed to form a variety of products which require antibacterial and/or antifungus properties.

Abstract: A medical device with an antimicrobial coating that is safe, effective, photostable and readily manufacturable can be produced by applying a composition to at least one body fluid-contacting surface of the device such that a solid coating is provided on that surface, the coating composition comprising an oligodynamic metal salt of a sulfonylurea, a polymeric material, at least one acid compound selected from the group consisting of a water-soluble carboxylic acid and water-insoluble carboxylic acid, and a carrier liquid in which foregoing components are soluble. The antimicrobial coating accommodates variation in the release of antimicrobial metal ions as a function of the intended use for a medical device to which the coating is applied.