Manganese Patents (Class 424/639)
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Publication number: 20130295146Abstract: It has now been found that after administration to a diseased person or person that is at risk for developing such disease of a neutraceutical or pharmaceutical composition that comprises: a) a lipid fraction comprising at least one of docosahexaneoic acid (DHA), docosapentaenoic acid (DPA) and eicosapentaenoic acid (EPA); b) a protein fraction comprising proteinaceous material from non-human origin which provide at least cysteine and/or taurine; and c) a mineral fraction comprising at least one of manganese and molybdene, the health of these persons improves. Membrane function of several types of mammalian cells improves, which allows efficient treatment of immune related disorders, such as allergy, autoimmune diseases, cancer, cognitive dysfunction and other diseases of the nervous system, neuropathies, such as diabetic neuropathies and neuropathic pains, neuronal damage during insulin resistance, and gut diseases and support of the development of gut and lung function during growth or recovery.Type: ApplicationFiled: July 2, 2013Publication date: November 7, 2013Applicant: N.V. NUTRICIAInventors: Robert Johan Joseph HAGEMAN, Mattheus Cornelis DE WILDE, Patrick Joseph Gerardus Hendrikus KAMPHUIS
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Patent number: 8563053Abstract: A composition and method for treating a bone condition of an animal. The composition includes a nanoformulation of active ingredients. The active ingredients include Lepidium Sativum or other Lepidium extracts, calcium, vitamin D, and antioxidants. The method for treating a bone condition includes introducing the composition into the animal.Type: GrantFiled: October 27, 2010Date of Patent: October 22, 2013Inventors: Shaker A. Mousa, Mohammed H. Qari, Mohammed S. Ardawi
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Patent number: 8562860Abstract: A method for activating hydrogen molecules dissolved in water and stabilizing the concentration of the hydrogen molecules is provided. The method for activating and stabilizing hydrogen molecules dissolved in water is characterized by allowing hydrogen ions to coexist with the hydrogen molecules.Type: GrantFiled: July 5, 2007Date of Patent: October 22, 2013Assignee: Spring Co., Ltd.Inventor: Osao Sumita
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Patent number: 8551513Abstract: A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Si, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.Type: GrantFiled: October 1, 2012Date of Patent: October 8, 2013Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
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Patent number: 8535710Abstract: A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.Type: GrantFiled: April 9, 2012Date of Patent: September 17, 2013Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
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Publication number: 20130202694Abstract: There is provided in accordance with embodiments of the invention a method of treating or reducing the effects in a subject of a condition selected from fructose intolerance and impaired fructose metabolism, the method comprising administering to a subject in need of such treatment or reduction an efficacious amount of a glucose isomerase, other than in combination with 5-D-fructose dehydrogenase. Other embodiments are also disclosed. There is provided a method for treating or reducing the effects of fructose intolerance and health problems associated with excessive fructose intake by administration of glucose isomerase. Other embodiments are also disclosed.Type: ApplicationFiled: March 15, 2013Publication date: August 8, 2013Inventors: Daniel Henry WYROBNIK, Isaac Harry Wyrobnik
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Publication number: 20130202696Abstract: There is provided in accordance with embodiments of the invention a method of treating or reducing the effects in a subject of a condition selected from fructose intolerance and impaired fructose metabolism, the method comprising administering to a subject in need of such treatment or reduction an efficacious amount of a glucose isomerase, other than in combination with 5-D-fructose dehydrogenase. Other embodiments are also disclosed.Type: ApplicationFiled: March 15, 2013Publication date: August 8, 2013Inventors: Daniel Henry WYROBNIK, Isaac Harry Wyrobnik
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Publication number: 20130183277Abstract: Provided are compositions and methods for increasing patient CD4+ cell count while undergoing treatment for immune-mediated disease, cancer, heart disease, neurodegenerative disease, or infectious disease by administering to the patient a nutrient composition including, inter alia, alpha lipoic acid, acetyl L-carnitine, and N-acetyl-cysteine.Type: ApplicationFiled: December 19, 2012Publication date: July 18, 2013Inventor: Jon D. Kaiser
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Publication number: 20130129787Abstract: Described herein is the synthesis of adhesive complex coacervates from electrostatically associated block copolymers, wherein the block copolymers comprise alternating polycationic and polyanionic blocks. Methods for making and the using the adhesive complex coacervates are also described herein.Type: ApplicationFiled: February 25, 2011Publication date: May 23, 2013Inventor: Russell J. Stewart
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Publication number: 20130108603Abstract: A topical skin care lotion includes materials for supplementing the production of collagen I and III includes a base of lipophillic or lipophobic material and at least one amino acid. The amino acids are alanine and glycine. Other components of the lotion include iron, vitamin C, manganese, silica and cherry fruit extract. Together, these components assist the body with the production of collagen and promote healing of damaged skin. Antioxidants are also provided to protect the skin from oxidative stress by ultraviolet sunlight and environmental hazards.Type: ApplicationFiled: November 2, 2011Publication date: May 2, 2013Inventor: Mark K. Bennett
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Publication number: 20130103120Abstract: There is disclosed therapeutic devices or sanitary articles intended for the treatment of diseases and/or disorders of the tonic/postural system, containing a composition which emits and/or reflects light energy in the far infrared spectrum and which includes a ceramic material. Also disclosed is the use of a composition which emits and/or reflects light energy in the far infrared spectrum and which includes a ceramic material in the preparation of therapeutic devices or sanitary articles intended for the treatment of diseases and/or disorders of the tonic/postural system, in particular, orthodontic devices, glasses and plasters.Type: ApplicationFiled: June 29, 2011Publication date: April 25, 2013Inventor: Sergio Ettore Salteri
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Publication number: 20130084272Abstract: The present invention relates to compositions, kits and methods for the administration of compositions and kits for supplementation with twelve carbon chain fatty acids or twelve carbon chain acylglycerols; and specifically for the supplementation with twelve carbon chain fatty acids such as lauric acid and twelve carbon chain acylglycerols such as monolaurin; and specifically for the co-supplementation with other vitamins, minerals and nutrients.Type: ApplicationFiled: September 29, 2011Publication date: April 4, 2013Inventors: Philippe PERRIN, Guillaume HERRY, Cecile BOYER-JOUBERT
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Publication number: 20130059012Abstract: The invention relates to methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions, particularly arthritis and joint pain, in felines, comprising measuring particular inflammatory biomarkers. The invention further provides a method to treat or control inflammation comprising administering a diet comprising increased levels of one or more of DHA, EPA, methionine, manganese, vitamin C, vitamin E, and/or L-carnitine.Type: ApplicationFiled: May 9, 2011Publication date: March 7, 2013Applicant: HILL'S PET NUTRITION, INCInventors: Samer Al-Murrani, Xiangming Gao, Junyu Lee, Sukhaswami Malladi, Nolan Zebulon Frantz
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Publication number: 20130052275Abstract: This invention is a topical treatment for the skin, used for skin enhancement, firming, smoothing, refining and to reduce the appearance of cellulite; that has a self-warming or thermogenic effect comprised of a base combination of warming herbs (Ayurvedic), being any herbs that create a warming effect, combined with dietary minerals that can be blended together in any ratio.Type: ApplicationFiled: August 22, 2012Publication date: February 28, 2013Inventor: Michelle Ward
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Publication number: 20130052279Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.Type: ApplicationFiled: March 24, 2011Publication date: February 28, 2013Applicant: MEDESIS PHARMAInventor: Jean-Claude Maurel
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Publication number: 20130052274Abstract: Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including exogenous vitamin K2. The nutritional compositions may further include an additional component selected from the group consisting of phosphorus, magnesium, zinc, iron, copper, manganese, calcium, vitamin D, osteopontin and combinations thereof.Type: ApplicationFiled: September 1, 2010Publication date: February 28, 2013Applicant: Nestec S.A.Inventors: Douglas Richard Bolster, Zamzam Kabiry Roughead
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Publication number: 20130052278Abstract: The present disclosure provides a rapidly disintegrating orally administrable powder. The powder may include an active ingredient such as a dietary supplement. Methods of using the same are also provided herein.Type: ApplicationFiled: March 10, 2011Publication date: February 28, 2013Applicant: RICH VITAMINS LLCInventors: Hallie N. Rich, Michelle G. Cannon
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Publication number: 20130045183Abstract: The present disclosure relates to non-acidic extracts or fractions selected from a Boswellia low polar gum resin extract fraction (BLPRE), a Boswellia volatile oil fraction (BVOIL), and a Boswellia oil fraction (BOIL) and their compositions. BLPRE, BOIL, and BVOIL are each derived from the gum resin of a Boswellia species. These compositions are useful for improving mental condition, enhancing brain functions such as cognition, memory, learning, communication and brain health, for treating impaired memory, and for preventing, control or treating memory and cognition related disorders/diseases. Additionally, BOIL, BVOIL, and mixtures of BOIL and BVOIL are useful for enhancing the bioavailability of a biological agent.Type: ApplicationFiled: September 14, 2012Publication date: February 21, 2013Applicant: LAILA NUTRACEUTICALSInventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI, Kiran BHUPATHIRAJU, Venkata Krishna Raju ALLURI
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Patent number: 8377482Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.Type: GrantFiled: September 7, 2005Date of Patent: February 19, 2013Assignee: Warburton Technology LimitedInventors: Robert N. Laurie, William A. Smith
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Publication number: 20130004588Abstract: Compositions and methods for treating and/or preventing conditions such as diaper rash and atopic dermatitis are disclosed. The compositions and methods are particularly useful in the treatment and prevention of diaper rash and diaper dermatitis caused by the prolonged contact of human skin with body waste. The methods employ the topical application of a trypsin-inhibiting agent to the area in need of such treatment, or the area where prevention is desired. The trypsin-inhibiting agent is preferably a divalent cation.Type: ApplicationFiled: June 28, 2011Publication date: January 3, 2013Inventors: Connie B. Lin, Euen Thomas Graham Ekman Gunn, Ya-Ping Hu, Neema Kulkarni, Mary Catherine Mack
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Publication number: 20120282350Abstract: The present invention relates to composition containing sialic acids or precursors, and their use to improve performance-related and social parameters in mammals, particularly humans and horses. The daily dosage is preferably selected from the group consisting of 1 microgram to 100 mg/day, 100 microgram to 20 mg/day, and 200 microgram to 10 mg/day.Type: ApplicationFiled: May 4, 2012Publication date: November 8, 2012Applicant: LIFE SCIENCE NUTRITION ASInventor: Jan Remmereit
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Publication number: 20120276218Abstract: A biocompatible composition for tissue repair or regeneration in mammals comprising one or more glass former compounds selected from the group consisting of B2O3, P2O5, and SiO2 and director elements selected from the group consisting of Cu, Sr, Zn, Fe, Mn, Cr, V, Nb, Mo, W, Ba, Co, S, Al, Ti, Y, Mg, Si and/or Ni to promote in vivo calcium compound formation of calcium carbonate or other calcium compounds other than hydroxyapatite. Upon direct application of the biocompatible composition to a mammalian host, calcium carbonate or other calcium compounds other than hydroxyapatite form upon bioreaction of the composition with bodily fluids.Type: ApplicationFiled: July 6, 2012Publication date: November 1, 2012Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURIInventors: Steven B. Jung, Delbert E. Day
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Publication number: 20120263798Abstract: The invention provides an entire line of deliciously flavored bottled water beverages with each flavor offering comprised of vitamins, minerals and nutritional supplements for fortifying the body. A sugar free, carbohydrate free and low sodium formula, Body Aqua features natural flavoring and natural sweeteners such as Stevia™. The Body Aqua product line contains ten varieties, with each formula designed to target a specific area of the body and promote overall health.Type: ApplicationFiled: April 4, 2012Publication date: October 18, 2012Inventor: Sherman Williams, JR.
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Publication number: 20120251450Abstract: Of the many compositions and methods provided herein, one composition includes a nanoparticle having a first oxide of a first metal and a dopant that includes an ion or an atom of a second metal. A method includes a method comprising providing a plurality of nanoparticles comprising a first oxide of a first metal and a dopant that comprises an ion or an atom of a second metal; providing a diseased cell and a healthy cell; contacting the diseased cell and the healthy cell with the nanoparticle; and allowing the nanoparticle to preferentially associate with the diseased cell.Type: ApplicationFiled: April 4, 2011Publication date: October 4, 2012Inventors: Alex Punnoose, Denise Wingett
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Patent number: 8273380Abstract: A beverage for minimizing or reducing jet lag symptoms preferably includes vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin D, zinc, calcium, iodine, magnesium, manganese, ginseng, ginkgo biloba, grape seed extract, Echinacea extract and water. A method for minimizing or reducing jet lag symptoms including ingestion of the beverage by a traveler, one hour prior to a flight, and/or during the flight, and/or after a flight.Type: GrantFiled: May 19, 2009Date of Patent: September 25, 2012
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Publication number: 20120231087Abstract: The present invention relates to nutritional supplement compositions comprising krill meal and lipid insoluble ingredients. The compositions can be used to provide supplementary nutrition to humans or animals. The present invention relates also formulations, such as tablets, which are easy to administer to animals. It is also shown that krill meal added to animal food at low levels will improve the palatability of the product.Type: ApplicationFiled: March 6, 2012Publication date: September 13, 2012Inventors: Inge Bruheim, Mikko Griinari, Stig Rune Remoy
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Publication number: 20120189709Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.Type: ApplicationFiled: January 11, 2012Publication date: July 26, 2012Applicant: ABBOTT LABORATORIESInventors: Debra L. Thomas, Pradip Mukerji
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Publication number: 20120177744Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.Type: ApplicationFiled: January 11, 2012Publication date: July 12, 2012Applicant: ABBOTT LABORATORIESInventors: Debra L. Thomas, Pradip Mukerji
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Publication number: 20120171130Abstract: A composition is able to treat plant and animal diseases and includes a therapeutically effective amount of an encapsulated ionic mineral complex and a pharmaceutically acceptable carrier. The composition may also include other inert ingredients, botanical extracts and vitamin and mineral supplements.Type: ApplicationFiled: October 31, 2007Publication date: July 5, 2012Inventor: John Wayne Kennedy
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Publication number: 20120148633Abstract: The present invention relates to galvanic particulates, their methods of manufacture and uses in treatments are described. The galvanic particulates may be binary or tertiary galvanic particulates, for example, containing multiple layers or phases of conductive materials.Type: ApplicationFiled: March 25, 2010Publication date: June 14, 2012Inventors: Ying Sun, Jue-Chen Liu, Michael Southall, Luiz Arthur Bonaci Tessarotto, Leon B. Kriksunov
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Patent number: 8192765Abstract: An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.Type: GrantFiled: November 3, 2008Date of Patent: June 5, 2012Assignee: ICET, Inc.Inventor: Shantha Sarangapani
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Patent number: 8178081Abstract: A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.Type: GrantFiled: July 13, 2010Date of Patent: May 15, 2012Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Bin Wu, Kevin P. McGrath, Jaeho Kim, Bao Trong Do, Sharon Linda Greene, Yanbin Huang, Kaiyuan Yang
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Publication number: 20120114743Abstract: Transdermal compositions containing castor oil are described. The compositions comprise ricinoleic acid and a transdermal vehicle with optional additional agents. One optional additional agent is an adrenergic drug which may cause the ricinoleic acid to penetrate the skin more deeply and have a longer lasting effect. The compositions can be used for treating a variety of ailments traditionally treated with castor oil or castor oil packs, without the mess and inconvenience of using castor oil packs.Type: ApplicationFiled: January 17, 2012Publication date: May 10, 2012Inventor: Keith Delprete
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Patent number: 8173154Abstract: A method and compositions for wound care management comprising a dressing comprising a three-dimensional body of glass-based fibers comprising 40 to 80 weight % B2O3, wherein at least 25 wt. % of the fibers have a diameter between 200 nm and 4000 nm, and a length:width aspect ratio of at least 10. The glasses may also be used for wound care as fibers formed into sutures, as particles in surgical glue to close a wound, or as particles in an ointment or cream to apply to a wound. The compositions may comprise glass formers P2O5 and/or SiO2; alkali oxides selected from Li2O, Na2O, K2O, and Rb2O; and/or alkaline earth oxides selected from MgO, SrO, BaO and CaO. The compositions may further comprise 0.05 to 10 wt. % of one or more trace elements selected from Ag, Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn.Type: GrantFiled: January 6, 2010Date of Patent: May 8, 2012Assignee: The Curators of the University of MissouriInventors: Steven B. Jung, Delbert E. Day
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Publication number: 20120100223Abstract: Lipid compositions comprising nuts, seeds, oils, legumes, fruits, grains, and dairy useful in specified amounts as dietary supplements and diet plans designed around and including the aforementioned for the prophylaxis and treatment of numerous diseases are disclosed. The compositions include omega-6 and omega-3 fatty acids where the ratio of the omega-6 to the omega-3 fatty acids and their amounts are controlled based on one or more factors including age of the subject, sex of the subject, diet of the subject, the body weight of the subject, medical conditions of the subject, and climate of the subject's living area.Type: ApplicationFiled: December 20, 2011Publication date: April 26, 2012Applicant: ASHA NUTRITION SCIENCES, INC.Inventor: Urvashi BHAGAT
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Publication number: 20120100119Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.Type: ApplicationFiled: December 8, 2011Publication date: April 26, 2012Applicant: Momentive Performance Materials Inc.Inventors: George A. Policello, Mark D. Leatherman, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
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Publication number: 20120087877Abstract: The invention relates to a composition based on mineral concentrates and a method of preparing this composition. The composition comprises a powder or a mixture of powders containing at least one silicon derivative and at least one trace element other than silicon, as a mixture with a carrier and physiologically acceptable excipients. Application in cosmetology and dermatology for protecting the skin.Type: ApplicationFiled: October 14, 2011Publication date: April 12, 2012Applicant: BULGARI PARFUMSInventors: Jean-Claude ALLART, Jean-Marie Lefevre, Jacques Peyrot, Jean-Paul Marty
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Patent number: 8142800Abstract: A practical high potency anti-craving oral medication or combined oral/IV drip medication is disclosed which comprises three components: a group of amino-acid substances, a group of vitamin substances, and a group of minerals, wherein each substance is selected for maximum efficacy in the body of an individual suffering from substance abuse disorder as opposed to the body of a healthy individual. The ingredients of the invention are selected to cooperate in easing metabolization in the bodies of individuals suffering the various medical conditions associated with substance abuse. The ingredients are provided orally to ease administration and to provide convenient use by patients: the oral medication may be a maintenance dosage or a corrective dosage.Type: GrantFiled: September 14, 2006Date of Patent: March 27, 2012Inventors: Tamea Rae Sisco, Keith Kenneth Skinner, Theodore Keller
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Patent number: 8142799Abstract: A practical high potency anti-craving medication is disclosed which comprises three components: an amino-acid component, a vitamin component, and a mineral component, wherein each component is selected for maximum efficacy in the body of an individual suffering from substance abuse disorder as opposed to the body of a healthy individual. Additionally, the active agents are received by means of a prolonged administration, preferably by means of an IV drip, thus assuring a period of time in which the active agents are present in desired concentrations, and more preferably a prolonged time during which they are simultaneously present in desired concentrations. The agents of each component are also selected so as to allow easy administration of the medication to patients in three vials of medication rather than as a large number of individual vials.Type: GrantFiled: August 20, 2005Date of Patent: March 27, 2012Inventors: Tamea Rae Sisco, Keith Kenneth Skinner, Theodore R Keller
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Publication number: 20120064052Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.Type: ApplicationFiled: June 22, 2011Publication date: March 15, 2012Applicant: Momentive Performance Materials Inc.Inventors: George A. Policello, Mark D. Leatherman, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
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Publication number: 20120064127Abstract: It has now been found that after administration to a diseased person or person that is at risk for developing such disease of a neutraceutical or pharmaceutical composition that comprises a) a lipid fraction comprising at least one of docosahexaenoic acid (DHA), docosapentaenoic acid (DPA) and eicosapentaenoic acid (EPA); b) a protein fraction comprising proteinaceous material from non-human origin which provide at least cysteine and/or taurine; and c) a mineral fraction comprising at least one of manganese and molybdenum, the health of these persons improves. Membrane function of several types of mammalian cells improves, which allows efficient treatment of immune related disorders, such as allergy, autoimmune diseases, cancer, cognitive dysfunction and other diseases of the nervous system, neuropathies, such as diabetic neuropathies and neuropathic pains, neuronal damage during insulin resistance, and gut diseases and support of the development of gut and lung function during growth or recovery.Type: ApplicationFiled: November 11, 2011Publication date: March 15, 2012Applicant: N.V.NUTRICIAInventor: Robert J.J. Hageman
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Publication number: 20120045518Abstract: Methods for controlling bleeding (e.g., enhancing coagulation and reducing fibrinolysis) in a subject are disclosed. The methods include selecting a subject in need of enhanced coagulation or reduced fibrinolysis, and administering to the subject a carbon monoxide releasing molecule (CORM). Examples of CORMs include tricarbonyldichloro-ruthenium (II) dimer, tricarbonylchloro-(glycinato)ruthenium (II), sodium boranocarbonate, dimanganese decacarbonyl, and iron pentacarbonyl. Further disclosed are compositions and methods for treating a subject in need of a blood product by administering to the subject a composition including a CORM and a blood product (e.g., cryoprecipitate or fresh frozen plasma).Type: ApplicationFiled: March 5, 2010Publication date: February 23, 2012Applicant: THE UAB RESEARCH FOUNDATIONInventors: Vance G. Nielsen, James F. George, James K. Kirklin
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Publication number: 20120034177Abstract: Disclosed are: a skin whitening agent comprising, as an active ingredient, a complex of carbonic acid and/or bicarbonic acid, a metal and an LF, a decomposition product of the complex, or a complex of carbonic acid and/or bicarbonic acid, a metal and a decomposition product of an LF; and a food, beverage, feed or cosmetic comprising the skin whitening agent. The skin whitening agent can be ingested safely on a daily basis, and exhibits an excellent skin whitening effect.Type: ApplicationFiled: October 14, 2011Publication date: February 9, 2012Applicant: SNOW BRAND MILK PRODUCTS CO., LTD.Inventors: Tatsuya WATANABE, Ken KATO, Hiroshi UENO, Yuko HARUTA, Noriko UEDA, Toshimitsu YOSHIOKA
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Publication number: 20120027869Abstract: Methods of using a non-irritant, low pH acidic composition to destroy undesirable microorganisms are described. The methods may be used on food products, food processing equipment, and in aqueous solutions.Type: ApplicationFiled: July 14, 2011Publication date: February 2, 2012Inventors: Barry Cummins, David Creasey
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Publication number: 20120021014Abstract: Metal particulates capable of generating low levels of corrosion current beneficial for pharmaceutical, cosmetic and other medical uses are provided.Type: ApplicationFiled: July 20, 2011Publication date: January 26, 2012Inventors: Jeannette Chantalat, Jeffrey C. Geesin, James E. Hauschild, Julia Hwang, Wei Kong, Jue-Chen Liu, William R. Parrish, Michael D. Southall, Brooks Story, Ying Sun, Chunlin Yang
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Publication number: 20120015047Abstract: The invention relates to a biological preparation comprising orthosilicic and silicic acid, a primary (“constant/first”) osmolyte choline and a weak alkalinizing agent without free hydroxyl groups and to a method for preparing the preparation, comprising: i) hydrolyzing a silicon comprising choline solution thereby forming a choline stabilized orthosilicic acid and oligomers solution; ii) alkalizing the choline orthosilicic acid and oligomers solution by adding a weak alkalizing agent without hydroxyl groups; and iii) optionally adding a divalent trace element and/or secondary osmolyte, to biological preparation obtainable and its uses.Type: ApplicationFiled: May 23, 2011Publication date: January 19, 2012Inventor: DIRK ANDRÉ R. VANDEN BERGHE
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Publication number: 20120009276Abstract: This invention is based on the observed oxidative stress and increased risk on cardiovascular diseases in subjects with increased lipid peroxidation, in particular with women using oral contraceptives and in hormone replacement therapies. The invention provides compositions and combinations, particularly useful in preventing and or reducing the increased lipid peroxidation in subjects in need thereof. These compositions are based on the synergistic combination of zinc and/or a hydroxyl radical scavenger in reducing lipid peroxidation.Type: ApplicationFiled: August 6, 2010Publication date: January 12, 2012Applicant: PROBIOX SAInventor: Donat Eugene H. De Groote
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Publication number: 20110293740Abstract: A treatment system and method for osteopenia and osteoporosis using non-synthetic bio-available hormones, vitamins, minerals, and agents may be customized by varying the dosage and formulation of the components to maximize therapeutic effect, bioavailability, and patient comfort and compliance with their treatment method, the treatment system including a storage unit including a determined number of applications of hormones, minerals, and vitamins of appropriate dosages for treating the patient with osteopenia and osteoporosis.Type: ApplicationFiled: May 26, 2011Publication date: December 1, 2011Inventor: Karan Y. Baucom
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Publication number: 20110280927Abstract: A dressing composition for use as a skin dressing comprises an elastomeric-adhesive composition, and a zeolite comprising releasably adsorbed nitric oxide. The zeolite may comprise a transition metal cation such as Co, Fe, Mn, Ni, Cu, Zn, Ag or a mixture thereof as an extra-framework metal cation, preferably Zn. The elastomeric adhesive composition may be a hydrocolloid-adhesive composition comprising, hydrocolloid and elastomer. The dressing composition releases nitric oxide, which may have beneficial effects, when used on wounds or moist skin, with a substantially constant release rate over a long period of time. A dressing including a layer of the dressing composition has a backing layer and may have a release liner removably attached to the skin-contacting surface of the dressing layer.Type: ApplicationFiled: November 20, 2009Publication date: November 17, 2011Applicant: PQ SILICAS UK LIMITEDInventors: Abraham Araya, Alan Reginald Minihan, Paul Matthew Robbins, Sonya Theresa Broderick, Michael J. Waring
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Publication number: 20110280958Abstract: The present invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a dithiino-tetracarboximide of formula (I) and a metal salt (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. In particular the combinations according to the invention are useful to obtain plants with greener leaf color.Type: ApplicationFiled: April 14, 2011Publication date: November 17, 2011Applicant: Bayer CropScience AGInventors: Thomas Seitz, Ulrike Wachendorff-Neumann