Abstract: Acesulfame-metal complexes, formed from a trace element, preferably Fe, Zn, Cu, Mn, Co and 2 molecules of acesulfamic acid by precipitation reaction with the use of suitable salts, are distinguished by a pleasantly sweet taste and are therefore suitable as sweeteners, food supplements and for enrichment of food, medicaments and feeds with trace elements.

Abstract: The present invention relates to compositions without added iron and methods for prophylactic nutritional supplementation and therapeutic nutritional supplementation. Specifically, the method involves administering to an individual a composition comprising carotenoids, vitamin E, vitamin D, vitamin C, thiamine, riboflavin, niacin, folic acid, pyridoxine, biotin, pantothenic acid, cobalamin, magnesium, manganese, zinc, selenium, chromium, copper, alpha lipoic acid, and lutein, wherein the composition is free of added iron.

Abstract: Ectoparasites, such as fleas, ticks, mites and lice, are removed from a human or animal host after applying a composition to the affected area that causes desiccation of the organism. In one embodiment, treatment is effected by applying a substantially anhydrous composition that has a strong affinity for water. As the composition hydrates, it desiccates the pests and facilitates their mechanical removal, such as by combing.

Abstract: This invention relates to a pharmaceutical composition containing herbal ingredients for the treatment of diabetes mellitus and more particularly, to the antidiabetic composition comprising 1) 15 herbal ingredients (i.e., Shinseng Radix, Coptis Rhizoma, Ligustri Fructus Semen, Salix spp. Cortex, Rhei coreani Rhizoma, Anemarrhena Rhizoma, Salviae Radix, Scrophulariae Radix, Lycii Cortex Radicis, Reynoutriae Radix, Platycodi Radix, Astragali Radix, Puerariae Radix, Atractylis Rhizoma, and Morus alba Radix Cortex), 2) vitamins such as B1 and B6, and 3) zinc, manganese, chromium, germanium as inorganic materials.

Abstract: This invention relates, generally, to nutritional supplements which contain bioactive glass. These supplements are useful in both veterinary and human contexts. The compositions of the subject invention can be used to achieve a number of advantageous results including: enhancing the growth rates of young animals, osteogenic stimulation, strengthening the skeletal structure, and treating osteoporosis.

Abstract: A solution for urushiol induced contact dermatitis is provided for in a topical solution. According to the invention, a method is provided for applying a composition of substances to the affected area, working the composition into the affected area, and removing the composition from the affected area. The composition comprises at least one ethoxylate in combination with a supporting agent. It is believed that this combination binds to the available urushiol receptors rendering it inactive. The affinity of the receptors for the ethoxylates also appears to cause a release of the urushiol from its epidermal bonds for bonding to the composition. An inert scrubbing agent, such as polyethylene beads, can also be included to assist in the release of the urushiol. Acetylated lanolin alcohol, EDTA, a foam stabilizer, and water can also be added to the composition without effecting performance.

Abstract: The present invention relates to dietary supplements containing low doses of phytoestrogens for supplementing the specific phytochemical dietary needs of perimenopausal and menopausal women.

Abstract: The present invention provides methods for preventing, treating, and/or managing one or more cancerous conditions in a patient, such as a human. A multivalent metal oxide, such as Ag(I,III), Cu(I,III), Pr(III,IV), and Bi(III,V) oxides or a pharmaceutically acceptable derivative thereof, may be administered to the patient in an amount and for a period of time which is therapeutically effective to prevent, treat, and/or manage such condition(s). These cancerous conditions include systemic and external cancers, and may also include conditions and symptoms associated with cancer. The present invention also provides a pharmaceutical composition suitable for treating such cancerous conditions. The compositions of the invention may be adapted for at least one of subcutaneous injection, intramuscular injection, intravenous injection, infusion, transdermal, or topical application.

Abstract: A therapeutic composition comprising (i) at least one antigen or at least one in vivo generator of a compound comprising an amino acid sequence and (ii) at least one adjuvant comprising at least one pharmaceutically acceptable and water-soluble salt of an organic anion and a metal cation.

Abstract: An oral and injectable composition for mammals comprising a salt of glucosamine, such as glucosamine hydrochloride, sulfate, nitrate, or iodide, a chondroitin sulfate, hydrolyzed or native collagen, a sodium hyaluronate, chelated manganese ascorbate, and L-malic acid in powder form for oral ingestion or in a solution of sterilized water for injection. The composition acts as a chondroprotective agent which provides foundational support for the creation of new body tissue and cartilage growth in humans and animals. Other beneficial physiological properties include the enhancement of chondrocyte synthesis, the healing of chronic or acute wounds, the maintenance of healthy muscle and tissue, increasing the desirable concentration of hyaluronic acid, and anti-inflammatory activity.

Abstract: The present invention relates to a new makeup kit comprising a first, goniochromatic pigment composition which is intended to form a base layer and a second, conventional pigment composition having one of the colors of the first pigment, the second composition being intended to form a surface layer comprising decorative motifs. Depending on the viewing angle, therefore, it is possible to see the said motifs appear or disappear. This kit is intended in particular for making up the nails, lips, cheeks or eyelids, or else the body. The invention also relates to a method of making up the human face, lips or body.

Abstract: A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, fat, and other minerals. A preferred source of vitamin D activity is cholecalciferol, and a preferred osteoblast stimulant is ipriflavone. In addition to these basic ingredients, the composition can further include various other minerals known to occur in bone, vitamin C, and glucosamine sulfate, all of which exert beneficial effects on growth and maintenance of healthy bone. A method for benefitting human bone health involves administering a daily regimen of the dietary supplement.

Abstract: A composition for the relief of heat stress, particularly for restoration of electrolyte balance due to passive exposure to heat resulting in excessive transpiration/perspiration, without strenuous physical activity, comprises predetermined levels of selected electrolytes including, in part by weight, sodium ion not exceeding 250 parts, at least 100 parts of potassium ion, at least 100 parts of magnesium ion, and carbohydrates not exceeding 2.5% by weight, as needed for organoleptic purposes only. The composition can further include up to 30 parts of zinc, up to 10 parts of manganese, and from 65 to 400 parts of calcium. Furthermore, the composition can comprise oligoelements, dermoprotective vitamins and anti-oxidants so as to compensate for the chemical changes which might occur in the skin of a person passively exposed to heat.

Abstract: A biocidal composition composed of a ternary complex of a negatively-charged biocide, a transition metal ion and chelator has synergistic biocidal effects as compared with a composition of each of the components alone. The chelator is preferably a neutral or positively-charged chelator. The ternary complex may be used for killing or inhibiting the growth of living cells.

Abstract: An inorganic antimicrobial composition has the formula AB2O4, wherein A and B are low temperature far infrared irradiating metals, A is Mg, Zn, Mn, Ni, Co, or Fe(II), B is Al, Cr(III), Mn(III) or Fe(III), and O is oxygen. An antimicrobial article is made by coating said composition on a porous honeycomb-shaped substrate. An organic antimicrobial article is made from a quaternary ammonium salt coated on a porous honeycomb-shaped substrate. Processes of making the antimicrobial articles are provided.

Abstract: The antioxidation food product of the present invention is a fermented product produced by adding a manganese-containing natural material such as tea and fermenting with bacteria having a catalase activity (e.g. Lactobacillus plantarum). The antioxidation food product has an antioxidation action in the living body including the interior of a digestive tract by expressing a superoxide dismutase-like activity and a catalase activity, simultaneously, and is effective for preventing diseases caused by active oxygen.

Abstract: A solid preparation for dialysis for preparing a double preparation type sodium bicarbonate solid preparation for dialysis in which there is no fear that a sugar component is decomposed or colored, and which can maintain stability and is also excellent in content homogeneity and a process for producing the same. The solid preparation for dialysis is a mixture of a first composition composed of core particles including sodium chloride and a coating layer containing one or more electrolytes, a second composition composed of core particles including a sugar that is covered with a coating layer comprising the same sugar or a different sugar, and an acid.

Abstract: A storage stable magnesium oxychloride coated granular animal feed mineral supplement composition resistant to disintegration cause by moisture absorption and attrition, comprising granular mineral nutrients useful as animal feed supplements and magnesium oxychloride coatings amounting to between 0.5 and 10.0 percent of the weight of the granules, formed on the granules of mineral nutrients by coreaction of magnesium chloride and magnesium oxide. An additional coating of between 0.2 and 2.0 percent magnesium stearate formed on the magnesium oxychloride may be used to decrease the rate of wetting of the granular animal feed mineral supplements.

Abstract: Compositions and methods using same for the treatment of diabetes its sequelae and pre-diabetic conditions are provided. Invention compositions include the anti-diabetic agent metformin, and bioavailable sources of one or more of chromium, vanadium and magnesium. Also provided are pharmaceutical agents containing invention compositions and methods for administering such agents.

Abstract: A hair growth formulation. The two basic main ingredients are castor oil and a special lemon extract. The special lemon extract is made from fresh lemon peel. The peel, including the bioflavonoids membrane, is blended with purified water until it is liquidified. Then the mixture is filtered through a sanitized cloth. Other ingredients that have been found helpful include: inositol, choline (from bitartate), niacinamide or nicotinic acid, manganese in chelated form, bioflavonoids, and folic acid. Finally perfume and sodium benzoate (as a preservative) can be added.

Abstract: A regime/regimen for relaxing and/or slackening human cutaneous and/or subcutaneous tissue, in particular for treating wrinkles and fine lines in the skin, comprising administering to an individual subject in need of such treatment, a thus-effective amount of manganese and/or at least one organic and/or inorganic salt thereof.

Abstract: A regime/regimen for relaxing and/or slackening human cutaneous and/or subcutaneous vascular tissue and for combating skin pallor, and/or for restoring stress-modified vascular equilibrium, comprising administering to an individual subject in need of such treatment, a thus-effective amount of manganese and/or at least one organic and/or inorganic salt thereof.

Abstract: The invention deals with phosphate water solution with cold solidification capacity. Phosphate composition containing iron oxide solution in acid, water, advantages from the following properties; it contains orthophosphorus acid and in addition metal powder. Phosphate composition is ecologically pure product, non toxic, non cancerogenic, non-allergic. It has antimicrobial, antivirus and fungicidal properties. Phosphate composition can be applied within medicine: surgery, dermatology, dentistry, oncology, pharmacology and other branches. In agriculture use: as a means of curing plant diseases, within veterinary—as a means for preventive maintenance and curing of animal diseases, within construction—as an anticorrosive, fire-resistant, hydro-electric isolating covers, ceramic tiles, concretes, which protect against radiation, as well as for producing other composite materials.

Abstract: A therapeutic composition comprising (i) at least one antigen or at least one in vivo generator of a compound comprising an amino acid sequence and (ii) at least one adjuvant comprising at least one pharmaceutically acceptable and water-soluble salt of an organic anion and a metal cation.

Abstract: The present invention relates to dietary supplements containing low doses of phytoestrogens for supplementing the specific phytochemical dietary needs of perimenopausal and menopausal women.

Abstract: Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.

Abstract: The present invention relates to compositions and methods of induction of a cellular stress response and a protected phenotype using heavy metal ions. The invention relates to methods of protecting a mammal against injury caused by a noxious condition by administering to the mammal a heavy metal in sufficient quantity and under appropriate conditions to induce a sufficient cellular stress response to provide protection (partial or complete) against injury caused by a noxious condition. The invention also relates to methods of inducing a cellular stress response in a mammal by administering a heavy metal in sufficient quantity and under appropriate conditions to induce a cellular stress response to protect the mammal against injury caused by a noxious condition.

Abstract: A therapeutic composition comprising (i) at least one antigen or at least one in vivo generator of a compound comprising an amino acid sequence and (ii) at least one adjuvant comprising at least one pharmaceutically acceptable and water-soluble salt of an organic anion and a metal cation.

Abstract: The present invention relates to nutritional supplements to the human diet used to increase levels of high density lipoprotein (HDL) and calcium ions, and decrease levels of free radicals and glucose in human blood plasma. More specifically, the present invention teaches novel nutritional supplements which comprise a novel combination of specific antioxidants, barley grass extract, specific multiple vitamins and minerals, and ginkgo biloba extract, as well as methods of preparing the nutritional supplements.

Abstract: The invention provides methods for producing edible plant tissue biomasses suitable for use as nutritional supplements. The seedlings are exposed to at least one metal and normal seedling growth is interrupted prior to the eleventh day following germination to thereby produce a metal-enriched plant seedling tissue biomass. The metal-containing edible plant tissue biomasses are also provided.

Abstract: An inorganic antimicrobial composition has the formula AB2O4, wherein A and B are low temperature far infrared irradiating metals, A is Mg, Zn, Mn, Ni, Co, or Fe(II), B is Al, Cr(III), Mn(III) or Fe(III), and O is oxygen. An antimicrobial article is made by coating said composition on a porous honeycomb-shaped substrate. An organic antimicrobial article is made from a quarternary ammonium salt coated on a porous honeycomb-shaped substrate. Processes of making the antimicrobial articles are provided.

Abstract: Microbicidal formulations are described which are preferably ecologically friendly and non-toxic to mammals, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains complexes having the formula R-M, wherein R is at least one organic chelating moiety and M is at least one metal ion which is microbicidal to at least one microorganism. These complexes can disrupt microorganism activities by penetrating the natural protecting bio-films of such microorganisms through the reaction of the R-group with the organic constituents of these microorganisms while releasing M into their intra-cellular media. Thus, this process exhibits its biocidal activities from the inside-out, contrary to other methods which rely on damaging the protective biofilms.

Abstract: The antioxidation food product of the present invention is produced by fermenting a food product containing bacteria having catalase activity, such as Lactobacillus plantarum, in the presence of a manganese-containing natural material. The antioxidation food product has antioxidation activity in vivo, including the digestive tract, by simultaneously expressing a superoxide dismutase-like activity and a catalase activity, and is effective for preventing diseases caused by active oxygen.

Abstract: Novel dietary complexes for gastrointestinal symptoms and gastrointestinal microbes are provided. They comprise a dietary metal and a dietary ligand wherein the dietary metal is selected from zinc, copper, cobalt, manganese and iron and the dietary ligand is lawsone or tropolone.

Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.

Abstract: There is described a foamable formulation comprising a foamable carrier and an active ingredient which may be admixed with the carrier or packaged separately and dispersed into the carrier during the foaming process. Alginate gel is a preferred foamable carrier. The foam produced from such a formulation, and a foam sheet produced by drying the foam, also form part of the invention. The formulation, foam and foam sheet are especially useful for medical applications, for example in treating burns. As apparatus to store the components of the formulation and to generate the foam is also described.

Abstract: Compositions for the treatment and prevention of migraine or stress headaches wherein there is supplied a combination of potassium, magnesium and pyridoxine optionally in association with other nutrients and/or simple analgesics.

Abstract: The present invention relates to heavy metal chelate compositions, which are used as fungicides and bactericides, and methods of using the compositions. In particular, the present invention relates to a chelate, that is an EDDHA (copper-ethylenediamine-di-o-hydroxyphenylacetic acid), combined with a heavy metal, including iron, tin, zinc, manganese, copper, and combinations thereof.

Abstract: The invention relates to an organometallic complex obtainable by reaction:of a cation of a metal (M) in an oxidation state at least equal to 2 useful as a biocatalyst in living metabolism,of a mixture of sitosterol and sitostanol, or of pure sitostanol or of a plant extract containing same,of the diglyceride of formula (I): ##STR1## in which: R.sub.1 is an acyl residue of oleic acid (C.sub.18 :1),R2 in an acyl residue of a linear or branched, saturated or unsaturated fatty acid having between 2 and 18 carbon atoms. More particularly, the invention relates to complexes in which R.sub.2 is an oleoyl or acetyl group. The invention also relates to pharmaceutical compositions containing this complex, particularly those wherein the metal is vanadium, and to their use in the treatment and/or the prevention of hypercholesterolaemia and/or of hypertriglyceridaemia, of insulin-dependent or non insulin-dependent diabetes, of insulin resistance and associated pathologies.

Abstract: The present invention is directed to a method of inhibiting the growth of disease organisms on and in plants by directly applying an aqueous solution comprising urea and at least one water-soluble salt of a divalent cation and a monovalent anion to the seeds, stems, bark, leaves, seed heads or sub-surface root zones of said plants. The weight percent ratio of urea to divalent cation in these solutions should be from about 0.25-10.0 to 1.0. Preferred divalent cations include those of the alkaline earth metals and the transition metals. Most preferred are calcium, magnesium, zinc, manganese, copper, iron, cobalt, nickel and mixtures thereof. Preferred anions include nitrate, chloride, bromide and mixtures thereof. In more preferred solutions, the ratio of urea to divalent cation is from about 2.0-7.0 to 1.0. Particularly preferred solutions include calcium chloride as the water-soluble salt. Optionally, a second water-soluble salt of a divalent cation and a monovalent anion may be included.

Abstract: Provided are methods for maintaining or enhancing the antimicrobial activity of antimicrobial peptides, lytic peptides, and peptide-derived antibiotics by the use of metal ions. Also provided are pharmaceutical and other compositions comprising such peptides and/or at least one metal ion. Also provided are therapeutic and other methods for controlling the growth of undesirable or pathogenic microorganisms in various loci or milieu in, on, or outside the body employing these peptides and metal ions. Also provided are kits comprising containers containing a peptide and a metal ion(s), respectively.

Abstract: A composition for use as a contrast medium being particularly suitable for imaging of the stomach, liver, bile duct and gall bladder, said composition comprising as an active ingredient a physiologically acceptable manganese compound and an uptake promoter, wherein the uptake promoter comprises a physiologically acceptable reducing compound containing a physiologically acceptable amino acid or a salt thereof, and/or vitamin D.

Abstract: A bolus for supplying a biologically beneficial substance to a ruminant animal, which includes a binder constituted by a rosin matrix, preferably pine rosin, together with a ballast material, such a zinc, with the biologically beneficial substance being dispersed in the binder, so that, in use, the biologically beneficial substance is released by leaching from the non-eroding body of the bolus. A pocket may be included in the body of the rosin bolus, which pocket erodes to release an additional biologically beneficial substance.

Abstract: The present invention relates to nutritional supplements to the human diet used to increase levels of high density lipoprotein (HDL) and calcium ions, and decrease levels of free radicals and glucose in human blood plasma. More specifically, the present invention teaches novel nutritional supplements which comprise a novel combination of specific antioxidants, barley grass extract, specific multiple vitamins and minerals, and ginkgo biloba extract, as well as methods of preparing the nutritional supplements.

Abstract: This invention relates to preservative compositions which comprise a biocidal metal compound and an fungicidal compound containing a triazole group. Methods of treating wood with the composition are also described.

Abstract: Cosmetic/dermatological/pharmaceutical compositions, well suited for the treatment of a variety of mammalian disorders of, for example, the skin, hair and/or mucous membranes, a manifestation of which is an excess in the synthesis and/or in the release of substance P, e.g., for the treatment of cutaneous disorders and sensitive skin, comprise an effective substance P antagonist amount of at least one salt of yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, tin, manganese, or mixture thereof, in a cosmetically/pharmaceutically acceptable medium therefor.

Abstract: The in vivo catalytic dismutation of hydrogen peroxide by pseudocatalase such as a transition metal bicarbonate complex is increased by the addition of a chelating agent, preferably ethylenediaminetetraacetic acid (EDTA), citic acid, 2,6-pyridinedicarboxylic acid, or a salt thereof Further, the stability of a topical composition comprising a transition metal bicarbonate complex is improved by storing the composition under carbon dioxide, preferably under pressure in aerosol form.

Abstract: A dietary supplement composition is disclosed which comprises a calcium salt, vitamin D and at least one mineral, preferably a boron compound. Other minerals may be present, in addition to, or instead of the boron compound, such as copper compounds, Magnesium compounds, manganese compounds and zinc compounds.

Abstract: An intra-ruminal, slow release bolus for supplying a biologically beneficial substance to a ruminant animal, wherein the beneficial substance, in the form of a relatively high density particulate such as copper oxide, is incorporated in a cylindrical block of a solid, non-toxic binding substance such as salt or sugar which in use dissolves and/or disperses within at most a few hours in the ruminant stomach, leaving the beneficial substance retained in the ruminant stomach for slow release over a period of months.

Abstract: Dermatological/pharmaceutical compositions, well suited for the therapeutic treatment of and/or alleviation of pain associated with at least one of the skin disorders, zona, poszoster, scald or burns, demodicidosis, skin ulcer, fibrosis, hypertrophic cicatrization and/or acne rosacea, comprise an effective substance P antagonist amount of at least one salt of yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, tin, zinc, manganese, cobalt, barium, strontium, or mixture thereof, in a dermatologically/pharmaceutically acceptable medium therefor.