Abstract: Metal particulates capable of generating low levels of corrosion current beneficial for pharmaceutical, cosmetic and other medical uses are provided.

Abstract: The invention relates to a biological preparation comprising orthosilicic and silicic acid, a primary (“constant/first”) osmolyte choline and a weak alkalinizing agent without free hydroxyl groups and to a method for preparing the preparation, comprising: i) hydrolyzing a silicon comprising choline solution thereby forming a choline stabilized orthosilicic acid and oligomers solution; ii) alkalizing the choline orthosilicic acid and oligomers solution by adding a weak alkalizing agent without hydroxyl groups; and iii) optionally adding a divalent trace element and/or secondary osmolyte, to biological preparation obtainable and its uses.

Abstract: This invention is based on the observed oxidative stress and increased risk on cardiovascular diseases in subjects with increased lipid peroxidation, in particular with women using oral contraceptives and in hormone replacement therapies. The invention provides compositions and combinations, particularly useful in preventing and or reducing the increased lipid peroxidation in subjects in need thereof. These compositions are based on the synergistic combination of zinc and/or a hydroxyl radical scavenger in reducing lipid peroxidation.

Abstract: An array of pharmaceutical formulations characterized by the presence of molecular oxygen comprising four elements which, in combination, furnish benefits for the health of patients with HIV AIDS: (i) weight increase of the patient; (ii) increase of appetite; (iii) reduction of diarrhea; (iv) reduction of the wasting syndrome; (v) increase of stability of mood; (vi) increase of muscular mass. (vii) decrease of opportunistic diseases, in particular infections caused by Candida, herpes virus, cytomegalovirus, Kaposi's sarcoma; (viii) prolongation of the period wherein the patient does not require to take antiretrovirals; (ix) increase of acceptance of pharmacological treatment; x. reduction of gastritis, nausea or vomiting, headache; (xi) reduction of cases with anemia or thrombocytopenia; and (xii) a change in the phase of the disease in the patient.

Abstract: A nutritional supplement for enhancing sleep and lucid dreaming in humans. It contains a combination of ingredients in proportions calculated to enhance lucid dreaming. The primary ingredients are Calea ternifolia, L-5-Hydroxytryptophan (L-5-HTP), and Vinpocetine. In addition, the nutritional supplement may include the secondary ingredient Melatonin and the tertiary ingredients Wild Lettuce Extract, Mugwort Extract, Dimethylaminoethanol Powder (DMAE), Passionflower Extract and Green Tea Extract. Further, various Vitamins may be added such as certain B vitamins, D and C, as well as Zinc, Magnesium and Calcium. The selection and amounts of the ingredients of the nutritional supplement promotes sleep and lucid dreaming in people who have taken the nutritional supplement prior to going to sleep.

Abstract: An antibacterial agent of the present invention contains a metal-containing compound containing a metal other than aluminum, and a phosphorus-adsorbing material. A method of using an antibacterial agent of the present invention is a method for improving an antibacterial property of a metal-containing compound containing a metal other than aluminum, wherein the metal-containing compound and a phosphorus-adsorbing compound are used in combination. Thus, the present invention provides an antibacterial agent, and a method of using an antibacterial agent, wherein an antibacterial property of a metal-containing compound containing a metal other than aluminum, particularly a silver-containing compound, is improved significantly.

Abstract: The present invention relates to a controlled release pharmaceutical or food formulation comprising at least one active pharmaceutical or food ingredient dispersed in a mixture of a glycogen with a polysaccharide, and the process for its preparation. The invention also relates to a slow release system represented by a mixture of a glycogen with a polysaccharide, and its use for the preparation of slow release pharmaceutical or food formulations.

Abstract: The invention relates to a domestic appliance, such as an iron, provided with a surface layer. The surface layer comprises an antimicrobial agent associated with a carrier, the carrier being inorganic and selected such that the antimicrobial activity of the surface layer according to JIS Z2801:2000 has a value of at least 2 after 100 hours of continuous use at a temperature of at least 230° C. In a preferred embodiment, the carrier is selected from the group consisting of a phosphate and a soluble silicate, while the antimicrobial agent is preferably selected from a group comprising ions of silver, zinc, copper, selenium, platinum or a combination thereof. The appliance stays fresher for a longer period of time than known hitherto. The invention further relates to an iron, a steam ironing device and a method of manufacturing the appliance.

Abstract: The present invention relates to a method of treatment and/or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and/or marine oil to a patient. The present invention also relates to a composition for the treatment and/or prevention of these diseases.

Abstract: Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, articles of manufacture, systems, and devices. Certain embodiments relate to anti-viral compositions, methods, articles of manufacture, systems and devices.

Abstract: The invention relates to pharmaceutics and to the pharmaceutical and food industries, in particular, to the production of compositions for stimulating the mucous membrane, ameliorating skin integument, and enhancing the organism's immunity. The aim of the invention is to develop a compound containing a thick pine needle extract with an improved quality composition in order to increase the biological activity of components and to preserve the processing characteristics and stability of the thick pine needle extract composition in capsular form. The aim is achieved by adding ?-tocopherol (vitamin E), retinol (vitamin A), naphthoquinones (vitamin K), essential fatty acids (vitamin F) and microelements (zinc, selenium), with a specified component ratio, into the thick pine needle extract composition for capsulation.

Abstract: A broad spectrum antimicrobial composition consisting essentially of an iodopropynyl compound in combination with a benzimidazole and a metal borate is disclosed. The composition can be used to protect industrial systems against microbial growth and, more particularly, to protect substrates such as paints, coatings, stucco, concrete, stone, cementaceous surfaces, wood, wood-plastic composites, caulking, sealants, textiles, leather, wood, preservatives, metal working fluids, drilling muds, clay slurries, glazes, optical brighteners, carpet backing, and pigments against microbial growth. The composition can be used as a preservative for aqueous products.

Abstract: A dressing composition for use as a skin dressing comprises an elastomeric-adhesive composition, and a zeolite comprising releasably adsorbed nitric oxide. The zeolite may comprise a transition metal cation such as Co, Fe, Mn, Ni, Cu, Zn, Ag or a mixture thereof as an extra-framework metal cation, preferably Zn. The elastomeric adhesive composition may be a hydrocolloid-adhesive composition comprising, hydrocolloid and elastomer. The dressing composition releases nitric oxide, which may have beneficial effects, when used on wounds or moist skin, with a substantially constant release rate over a long period of time. A dressing including a layer of the dressing composition has a backing layer and may have a release liner removably attached to the skin-contacting surface of the dressing layer.

Abstract: An antibacterial melamine product includes a main body that is formed by heating and filling molding to have a predetermined shape. The main body includes a substrate portion and an antibacterial agent mixed with the substrate portion. The substrate portion is made of melamine formaldehyde. The antibacterial agent is fused in the substrate portion evenly. Thus, the antibacterial agent is mixed with the substrate portion to form the main body so that the main body of the antibacterial melamine product has different antibacterial effects by the antibacterial features provided by the antibacterial agent.

Abstract: It is described the use of L-carnitine, in combination with antioxidants such as vitamin E and inorganic elements such as manganese, zinc, sodium and potassium, for the preparation of a physiological supplement or medicament for opthalmic use, for the prevention or treatment of accomodative asthenopia.

Abstract: A method for producing a cactus fruit extract for use in formulating a beverage which can be used in the treatment of veisalgia.

Abstract: It is described a composition comprising as active ingredients green tea extract and pomegranate extract for the prevention or reduction of the progression of prostate cancer.

Abstract: A core-shell nanoparticle having a core that includes a fluorophore and a first oxide of a first metal and a shell that includes a second oxide of a second metal such that the first oxide and the second oxide are different. Also disclosed are methods relating to the core-shell nanoparticle.

Abstract: The present disclosure provides a dual-action pest control formulation for controlling rodents and arthropods, the formulation including: a rodenticide; an insecticide; an optional attractant; and a carrier matrix. The present disclosure also provides a method of controlling rodents and arthropods, the method including: applying the dual action pest formulation to a target area.

Abstract: We disclose a colorless composition comprising metal particles (e.g., silver nanoparticles) and water, wherein said particles comprise an interior of elemental metal (e.g., silver) and an exterior of metal oxide (e.g., one or more silver oxide(s)), wherein the metal nanoparticles are present in the water at a level of about 5-40 ppm, and wherein the composition manifests significant antimicrobial properties. Methods of use of the composition are described. The composition can be incorporated into a hydrogel with essentially no loss of antimicrobial properties. Various metal-containing compositions with unexpected biological efficacy are also disclosed.

Abstract: Methods and compositions are described for treating acne vulgaris and acne rosacea by administering compositions suitable for oral administration. Suitable compositions contain high dosages of the vitamin nicotinamide combined with much lower dosages of azelaic acid.

Abstract: The present invention relates to a pearl pigment obtained by coating the surface of a flaky powder with a colored metal or a colored metal oxide and further coating the surface of the above colored metal- or colored metal oxide-coated flaky powder with a colorless metal or a colorless metal oxide, wherein when the pearl pigment is applied onto the surface of black artificial leather in an average amount of 0.05 mg/cm2 and the intensity of light reflected from the pearl pigment is measured using illuminant C at a 2° viewing angle with a spectrophotometric colorimeter which is provided with a sheet polarizer S on the light incident side and a sheet polarizer P on the light receiving side, the powder reflection light which is incident to the pearl pigment as a measurement sample at an angle of 45° to the direction normal to the surface of the sample and is received in the direction normal to the surface of the sample has absolute values a* and b* of 10 or less, and make-up cosmetics containing the pearl pigment.

Abstract: A composition and method for promoting hair growth comprising oral administration of a whey protein based formulation containing particular percentages of vitamins and supplements from between 2 weeks to 6 months.

Abstract: The present invention relates to a method for protecting a human patient or a mammalian animal to be subjected to chemotherapy treatment of a tumor not residing in the scalp of the patient or the skin of the animal against chemotherapy-induced alopecia, comprising administering to the scalp of the patient or the skin of the animal an effective amount of a composition comprising a chemical inducer of the stress protein response sufficiently prior to the administration of a chemotherapeutic drug. It also relates to pharmaceutical compositions for the prevention of chemotherapy-induced alopecia. It further relates to a method for protecting a human patient or a mammalian animal to be subjected to chemotherapy treatment of a tumor not residing in the scalp of the patient or the skin of the animal against chemotherapy-induced alopecia, comprising administering to the scalp of the patient or the skin of the animal an effective heat dose sufficiently prior to the administration of a chemotherapeutic drug.

Abstract: A carrier system for transport of functional chemicals in substrates, such as fiber and plastic materials, comprises a carrier compound and at least one functional chemical, whereby the carrier compound consists of micelles, liposomes, lyotropic liquid crystals, or intercalation compounds. The functional chemical that is transported by the carrier compound migrates into the substrate and has an anisotropic distribution therein. Methods for modification, for activation and deactivation in a subsequent application on substrates are described.

Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.

Abstract: Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such as idiopathic cardiomyopathy, metabolic cardiomyopathy which includes diabetic cardiomyopathy, alcoholic cardiomyopathy, drug-induced cardiomyopathy, ischemic cardiomyopathy, and hypertensive cardiomyopathy, (ii) atheromatous disorders of the major blood vessels (macrovascular disease) such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the femoral arteries, and the popliteal arteries, (iii) toxic, drug-induced, and metabolic (including hypertensive and/or diabetic disorders of small blood vessels (microvascular disease) such as the retinal arterioles, the glomerular arterioles, the vasa nervorum, cardiac arterioles, and associated capillary beds of the eye, the kidney

Abstract: The invention relates to a versatile disinfectant containing as main components, a metal ion having an antimicrobial action, L-cysteine and L-ascorbic acid, characterized in that it contains a surfactant excluding a nonionic surfactant in addition to these main components. The versatile disinfectant may further contain one or more compounds selected from the group consisting of sorbic acid, sorbates, benzoic acid, benzoates and p-hydroxybenzoate esters. The pH of the versatile disinfectant is preferably adjusted to 2.5 to 4.0. The disinfectant can disinfect an object to be treated for an environment, an apparatus, a human body, an animal body, a plant body, an organic matter or the like by bringing the disinfectant into contact with such an object to be treated.

Abstract: The present invention generally relates to the field of nutrition, in particular performance nutrition. In particular, the present invention relates to a novel carbohydrate bar comprising glucose and fructose in a ratio in the range of 3:1 to 1:1. The carbohydrate bar of the present invention can be used to treat or prevent problems with the gastrointestinal tract while allowing for an enhanced blood sugar maintenance and/or an increased exogenous carbohydrate oxidation.

Abstract: The vitamin strip is made with gel, film, or dissolvable material safe for human consumption. It can encompass all the vitamins, minerals, medicines, or meal replacement elements safe for human intake. The vitamin strip (V1) can be made as a whole or as a strip of edible dissolvable material with any vitamin(s), mineral(s), medicine(s), or meal replacement element(s) safe for human consumption on the strip of edible dissolvable material.

Abstract: The composites disclosed herein comprise silica and an antimicrobial metal oxide. The composites are useful in inhibiting microbial growth and are therefore useful in a variety of applications, including, for example, as components in dentifrice compositions.

Abstract: Compositions and methods for treating inflammation in mammalian tissue are provided using substantially continuously, in situ generated, anti-inflammatory effective amounts of hydrogen peroxide.

Abstract: A Theraputic composition of glycyrrhizic acid, slippery elm, zinc oxide, allantoin, lysine monohydrochloride, L-Carnitine, Lipoic acid, Salicylic Acid, Citric Acid, vitamin E Acetate, wheat germ oil, and Shea butter for the treatment of HSV-1, HSV-2, canker sores, shingles, and other epidermal and oral ailments.

Abstract: The present invention provides antiviral compositions that comprise one or more of an ionic multivalent metal component, a cationic polymer, and a cationic surfactant. The present invention also provides methods for making and using such antiviral compositions.

Abstract: The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of an aptamer and to methods for treating or preventing a condition in an animal by administering to an animal in need thereof the pharmaceutical compositions.

Abstract: The invention consists of a granulated fertilizer which contains iron (11 to 13%), zinc (3 to 9%), manganese (0.1 to 2.5%), copper (0.5 to 0.7%), in the form of sulphates, also ammonium molybdate (0 to 0.1%) and a Caolinite, Illite or Montmorillonite clay (45 to 57%), or a mixture of them in any proportion. All the percentages by weight are based on the total weight of the fertilizer. The product is 100% soluble, the high cationic exchange capacity which clays have allows the micronutrients to be adsorbed by the clay and prevent its leaching or reacting, making its assimilation by the plant more efficient and better. The use of sulphates in the soil, in the presence of water provoks an acidification of the soil which allows a better assimilation of the micronutrients in alkaline soils.

Abstract: The invention relates to a drug or a dermatological composition containing an avocado peptide extract for treating and/or preventing pruritus, in particular gravidic pruritus, pruritus sine materia, pruritus in newborns, and pruritus originating from a drug.

Abstract: A composition of matter and the method of making that provide a low pH acidic composition that is useful for destroying microorganisms that are undesirable and useful for destroying or reducing melanoma on human skin. The composition and method include a strong, low pH acid combined with distilled water and urea or an ammonium compound, such as ammonium sulfate or other metallic sulfates, including but not limited to, sodium sulfate, magnesium sulfate, zinc sulfate, manganese sulfate, and copper sulfate, under at least 15 psi pressure in pressurized container, all of which is heated to approximately 800° F. or more for at least 3 hours. The final cooled mixture is stabilized with 10 to 15 percent of the original mixture. The resultant composition is useful for preserving food, such as fresh fish, and for skin treatment of melanoma and as bactericides, fungicides, or viricides.

Abstract: A chelation complex including 8-hydroxyquinoline and zinc mixed with a carrier demonstrates therapeutic efficacy in treating lesions including cancerous lesions, precancerous lesions, cysts and warts.

Abstract: Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such as idiopathic cardiomyopathy, metabolic cardiomyopathy which includes diabetic cardiomyopathy, alcoholic cardiomyopathy, drug-induced cardiomyopathy, ischemic cardiomyopathy, and hypertensive cardiomyopathy, (ii) atheromatous disorders of the major blood vessels (macrovascular disease) such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the femoral arteries, and the popliteal arteries, (iii) toxic, drug-induced, and metabolic (including hypertensive and/or diabetic disorders of small blood vessels (microvascular disease) such as the retinal arterioles, the glomerular arterioles, the vasa nervorum, cardiac arterioles, and associated capillary beds of the eye, the kidney

Abstract: A composition and method for treating mammals suffering from malignant tumors which involves administering a composition including ammoniated mercury, zinc oxide and citric acid.

Abstract: An anti-microbial composition includes a doped zinc oxide of formula Zn1-nMnO, where M is an alkali metal ion, an alkaline earth metal ion, a lanthanide metal ion, or a mixture of any two or more thereof; and n is about 0.05 to about 0.2.

Abstract: The use of the polyamine known as spermidine, i.e., N-(3-aminopropyl)tetraminethylenediamine, as an active principle in the preparation of a composition for pharmaceutical or dietetic use in man for combating hair loss is disclosed.

Abstract: An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which has generally been pretreated by being dissolved under relatively high temperature and concentration conditions. The composition typically includes at least about 5.0% (w/v) ascorbic acid and may advantageously be formulated to have a pH above 3.5. Generally, the composition also includes non-toxic zinc salt, tyrosine compound, and/or pharmaceutically acceptable carrier. In addition, the composition may include an anti-inflammatory compound, such as aminosugar and/or sulfur-containing anti-inflammatory compound. The topical composition may be in the form of a serum, a hydrophilic lotion, an ointment, a cream, or a gel.

Abstract: Disclosed herein are compositions and methods for the treatment and/or prevention of pathological conditions associated with ischemia/reperfusion injury and/or hypoxic injury of myocardial cell or tissue.

Abstract: The present invention is directed to the provision of multi-dose, self-preserved ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP), without requiring the presence of conventional anti-microbial preservative agents, such as benzalkonium chloride. The compositions are effectively preserved by a balanced ionic buffer system containing zinc ions at a concentration of 0.04 to 0.9 mM, preferably 0.04 to 0.4 mM. One aspect of the balanced buffer system is limitation of the amount of buffering anions present to a concentration of 15 mM or less, preferably 5 mM or less. In a preferred embodiment, the compositions also contain borate or, most preferably, one or more borate/polyol complexes. The use of propylene glycol as the polyol in such complexes is strongly preferred.

Abstract: An antiviral agent is provided which can inactivate a wide range of viruses. Products that include such an antiviral agent are also provided. The present invention provides an antiviral agent that contains as an active ingredient a particle of at least one kind of iodide composed of iodine and an element shown in Period 4 to Period 6 and Group 8 to Group 15 of a periodic table or at least one kind of monovalent copper compound. The antiviral agent of the present invention can be designed at a higher degree of freedom in terms of its constituents as compared to conventional antiviral agents. In addition, the antiviral agent can readily exhibit and maintain its antiviral activity because it doesn't require any pretreatments or special washing processes.

Abstract: The present invention discloses certain heterocyclic complexes of metals of formula (I), especially those of manganese, which enhance the safety and efficacy of sunscreens via urocanate pathway modulation.

Abstract: Multivitamin/Multimineral supplements are provided for supplementing iron and desirable nutrients in the diet of mammals. The supplements include an iron-amino acid chelate, a form of iron more bioavailable than traditional iron salts. The supplements may further include a pharmaceutically accepted salt form of iron as well as other nutritional vitamins and minerals. The supplements are useful for providing iron for pregnant and lactating females as well as for persons suffering from anemia.

Abstract: The present invention generally relates to a method of making nanoparticles and uses thereof. In particular, the invention relates to methods of making metal nanoparticles (MNPs). The invention also relates to antimicrobial uses of the nanoparticles.