Zinc Patents (Class 424/641)
  • Publication number: 20130078292
    Abstract: Provided is a formulation for oral teeth, which includes a plurality of calcium ion carriers and a plurality of calcium-containing particulates. The particulates are carried by the calcium ion carriers, such that the formulation can prevent or rapidly treat dentin-associated symptoms or diseases, while providing a prolonged prophylactic or therapeutic effect.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: SANCASTLE WORLDWIDE CORPORATION
    Inventors: Chun-Pin Lin, Hong-Ping Lin
  • Patent number: 8404263
    Abstract: The resent invention relates to an agrochemical formulation comprising a pesticide, an organic UV photoprotective filter and coated metal oxide nanoparticles. It also relates to a method for preparing said formulation. Further on, it also relates to the use of a mixture of an organic UV photoprotective filter and coated metal oxide nanoparticles in agrochemical formulations and the use of a agrochemical formulation according to the invention for stabilizing a pesticide against UV irradiation.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: March 26, 2013
    Assignee: BASF SE
    Inventors: Michael Ishaque, Gerhard Schnabel, Douglas D. Anspaugh
  • Patent number: 8404246
    Abstract: A nutritional supplement includes the primary ingredients: N-acetyl D-glucosamine, cracked cell wall Green Chlorella, Licorice Root Extract, and Potassium Citrate, as well as secondary ingredients: Zinc L-Carnosine, Gamma-Oryzanol and Capsaicin, that improves the bodies uptake, utilization and over-all bioavailability of exogenous target protein fractions (TPF) including but not limited to: glycoproteins, (such as glucosamine) protein isolates as amino acids, glycosaminoglycans (GAG) (including proteoglycans, and mucopolysaccharides), and polysaccharides such as hyaluronic acid (hyaluronan). The biochemical interactions of the composition improves zeta potential for TPF incorporation in the body through direct and indirect interaction with primary cellular and digestive sites of multiple species.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: March 26, 2013
    Inventor: Shawn Madere
  • Publication number: 20130071490
    Abstract: Embodiments disclosed herein relate to improved X-ray contrast media compositions and methods of using the same for treating symptoms related to allergic reactions, inflammatory conditions, symptoms of the common cold and certain cancers.
    Type: Application
    Filed: November 18, 2011
    Publication date: March 21, 2013
    Inventor: Elliott C. Lasser
  • Patent number: 8389019
    Abstract: Disclosed is a method for reducing boar taint in pigs, said method comprising injecting a solution of a pharmaceutically acceptable zinc salt into a dorsal cranial portion of each testis of a male pig preferably when the pig is less than one week old. The solution contains at least 20 mg of zinc ion per ml of solution and the solution is injected into the testis in a volume that is contained within the testis.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: March 5, 2013
    Inventor: Min Wang
  • Publication number: 20130052248
    Abstract: An item of clothing (10) for daily pharmacological treatment of a fungal infection, comprising: a textile material (20) to manage moisture when the item of clothing (10) is worn; microcapsules (30) grafted on the textile material (20); and antifungal agents encapsulated within the microcapsules (30) to pharmacologically treat the fungal infection when released from the microcapsules (30).
    Type: Application
    Filed: August 26, 2011
    Publication date: February 28, 2013
    Inventors: Marcus Chun Wah YUEN, Joanne Yiu Wan YIP, Kevin CHEUK, Chi Wai KAN, Shuk Yan CHENG
  • Publication number: 20130052274
    Abstract: Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including exogenous vitamin K2. The nutritional compositions may further include an additional component selected from the group consisting of phosphorus, magnesium, zinc, iron, copper, manganese, calcium, vitamin D, osteopontin and combinations thereof.
    Type: Application
    Filed: September 1, 2010
    Publication date: February 28, 2013
    Applicant: Nestec S.A.
    Inventors: Douglas Richard Bolster, Zamzam Kabiry Roughead
  • Patent number: 8383163
    Abstract: Fluoride varnish compositions for temporary application and adhesion to a person's teeth. The composition includes a carrier comprising a resin and an adhesion promoting agent comprising an alkyl phosphoric acid. A fluoride ion source (e.g., a fluoride salt such as sodium fluoride) is dispersed within the carrier so as to provide biologically available fluoride ions to the tooth tissue being treated. The composition adheres only temporarily to tooth tissue (e.g., for a period of at least about 4 minutes, but not more than about 1 year), after which the composition spontaneously wears away as a natural result of the action of the tongue, saliva and/or other factors.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: February 26, 2013
    Assignee: Ultradent Products, Inc.
    Inventors: Jeff A. Wagner, Andy T. Kawamoto
  • Publication number: 20130045183
    Abstract: The present disclosure relates to non-acidic extracts or fractions selected from a Boswellia low polar gum resin extract fraction (BLPRE), a Boswellia volatile oil fraction (BVOIL), and a Boswellia oil fraction (BOIL) and their compositions. BLPRE, BOIL, and BVOIL are each derived from the gum resin of a Boswellia species. These compositions are useful for improving mental condition, enhancing brain functions such as cognition, memory, learning, communication and brain health, for treating impaired memory, and for preventing, control or treating memory and cognition related disorders/diseases. Additionally, BOIL, BVOIL, and mixtures of BOIL and BVOIL are useful for enhancing the bioavailability of a biological agent.
    Type: Application
    Filed: September 14, 2012
    Publication date: February 21, 2013
    Applicant: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI, Kiran BHUPATHIRAJU, Venkata Krishna Raju ALLURI
  • Publication number: 20130045179
    Abstract: The present invention provides therapy and methods for the treatment and prevention of diseases of cell proliferation such as cancer, benign tumors, and viral diseases such as HIV-AIDS, hepatitis B, hepatitis C and cirrhosis. The methods of this invention consist of the administration to a patient of a combination of effective amounts of agents capable of eradicating the neoplastic cells, while sparing the non-neoplastic cells from cytotoxic side-effects. The agents co-administered in therapeutically effective amounts are: chemotherapeutic agents, apoptotic agents, anti-angiogenic agents, cell differentiation agents, immunomodulating agents, antioxidants, vitamins, microelements, enzymes and natural extracts.
    Type: Application
    Filed: August 15, 2011
    Publication date: February 21, 2013
    Inventors: Mihai Ciustea, Ghiorghe Ciustea
  • Publication number: 20130045283
    Abstract: A composition, system and method for modifying an olfactory response to an odorant is disclosed. In some embodiments, the composition includes crystalline metal nanoparticles dispersed in an aqueous medium. The composition is applied to olfactory tissues using a suitable applicator or dispenser. The metal nanoparticles are believed to interact with a G-protein coupled to receptor located in the cilia to moderate (enhance or reduce) sensitivity or ability to smell particular odorants. In accordance with an embodiment of the invention, the composition includes one or more odorants.
    Type: Application
    Filed: September 21, 2012
    Publication date: February 21, 2013
    Applicant: AUBURN UNIVERSITY
    Inventor: Auburn University
  • Patent number: 8377454
    Abstract: A profertility composition for administration to infertile men with sperm oxidative stress is disclosed. The composition comprises a unique combination of a pharmaceutically acceptable vitamin E, vitamin C, selenium, zinc, folic acid, lycopene and at least one carnitine source.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: February 19, 2013
    Inventor: Parviz Gharagozloo
  • Patent number: 8377482
    Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: February 19, 2013
    Assignee: Warburton Technology Limited
    Inventors: Robert N. Laurie, William A. Smith
  • Publication number: 20130039953
    Abstract: A method for treating a surface with a therapeutic agent is disclosed. The method comprises precipitating a therapeutic agent from a hydrophilic polymeric base layer with which the therapeutic agent has been complexed, to form a layer comprising microparticles of the therapeutic agent on the hydrophilic polymeric base layer, the hydrophilic polymeric base layer being grafted to the surface. Devices comprising a surface having a hydrophilic polymeric base layer comprising a hydrophilic polymer grafted to the surface and a layer comprising microparticles of a therapeutic agent disposed on and complexed with the hydrophilic polymeric base layer are also disclosed.
    Type: Application
    Filed: July 6, 2012
    Publication date: February 14, 2013
    Applicant: Covalon Technologies
    Inventors: Vyacheslav Dudnyk, Valerio DiTizio
  • Publication number: 20130034594
    Abstract: A fiber containing ferrate, which comprises (1) one or more ferrate compounds, wherein the ferrate compound is selected from a group consisting of a metal ferrate(V) compound, metal ferrate(VI) compound, and a mixture thereof; and (2) one or more nonaqueous polymers. Also, methods are disclosed that make and/or use the fibers.
    Type: Application
    Filed: April 21, 2011
    Publication date: February 7, 2013
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Bruce F. Monzyk, Robert D. Giammar, Ada Cowan
  • Patent number: 8367121
    Abstract: This invention describes a comprehensive nutraceutical designed to antagonize major mitigating factors to the degenerative process associated with Parkinson's disease. The formulation is comprised of a primary base of pyruvate, succinate, ?-Ketoglutarate and/or oxaloacetate, niacin/NADH, fruit extracts, anthocyanins, further combined with specific macro/micronutrients, trace elements, amino acids, flavonoids and concentrated plant sources. The nutraceutical contains all natural substances that should mitigate many of the neurodegenerative processes known to be associated with PD. Mechanisms addressed are to prevent the loss of ATP/by 1-methyl-4-phenylpyridinium rotenone, scavenge hydrogen peroxide/O2.
    Type: Grant
    Filed: February 6, 2010
    Date of Patent: February 5, 2013
    Assignee: Florida A & M University
    Inventors: Elizabeth Anne Mazzio, Karam F Soliman
  • Patent number: 8361513
    Abstract: The present invention herein provides antimicrobial zeolite which hardly causes any color change with the elapse of time even when it is incorporated into a resin to form an antimicrobial resin composition. The present invention thus relates to antimicrobial zeolite which comprises zeolite whose ion-exchangeable ions are partially or wholly replaced with hydrogen ions and silver ions; and an antimicrobial resin composition which comprises the foregoing antimicrobial zeolite in an amount ranging from 0.05 to 80% by mass.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: January 29, 2013
    Assignee: Sinanen Zeomic Co., Ltd.
    Inventors: Akio Taniguchi, Kumiko Miyake, Yasuo Kurihara
  • Patent number: 8361512
    Abstract: Provided are methods and compositions for increasing CD4+ cell count in mammals, preferably by at least 25%, while undergoing treatment for various conditions whose treatment can have detrimental effects on immune system function. Such conditions include, but are not limited to, HIV infection, cancer, and hepatitis. The compositions include alpha lipoic acid; acetyl L-carnitine; N-acetyl-cysteine; zinc; selenium; vitamin C; bioflavinoid complex; vitamin E; optionally one or more antioxidants selected from co-enzyme Q10 and glutathione; and one or more vitamins or minerals selected from beta-carotene, vitamin A, vitamin B1, vitamin B2, vitamin B6, niacinamide, calcium pantothenate, folic acid, vitamin B12, copper, manganese, chromium, and molybdenum.
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: January 29, 2013
    Assignee: K-PAX Vitamins, Inc.
    Inventor: Jon D. Kaiser
  • Patent number: 8357696
    Abstract: Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: January 22, 2013
    Assignee: Mpex Pharmaceuticals, Inc.
    Inventors: Mark W. Surber, Keith A. Bostian, Michael N. Dudley, Olga Rodny, David C. Griffith
  • Publication number: 20130011494
    Abstract: The various embodiments herein disclose a composition in the form of an ointment for treating decubitus ulcers in diabetic and non diabetic patients. The composition comprises of therapeutic agents, zinc oxide, vegetable oils and powdered talc. The therapeutic agents include salts of nystatin, tetracycline and neomycin, respectively. The vegetable oils include an olive oil, a soya oil and a sweet almond oil. The composition is effective in treatment of bed sore ulcers or decubitus ulcers in, both diabetic and non-diabetic patients. A method is also provided for preparing a composition in the form of an ointment for treating decubitus ulcers.
    Type: Application
    Filed: July 10, 2011
    Publication date: January 10, 2013
    Inventor: Mohammad Rahimi
  • Publication number: 20130004586
    Abstract: Compositions, solid polymeric compositions, and/or articles of manufacture are provided that can include a polymer matrix having a plurality of ion-exchange particles distributed therein. Products by process are provided that can include prior to solidifying the polymeric precursors, blending the precursors with ion-exchange particles to form a mixture, and solidifying the mixture to form a solid polymeric composition product. Solid polymeric composition production methods are also provided that can include providing a plurality of ion-exchange particles, prior to solidifying the polymeric precursors, blending the precursors with the ion-exchange particles to form a mixture, and solidifying the mixture to form a solid polymeric composition. Article of manufacture production methods are provided that can include incorporating a solid polymeric composition into an article of manufacture, the solid polymeric composition including a polymer matrix and a plurality of ion-exchange particles distributed therein.
    Type: Application
    Filed: June 25, 2012
    Publication date: January 3, 2013
    Inventors: David J. Vachon, Nathan Knapp
  • Publication number: 20130004590
    Abstract: Compositions and methods for treating and/or preventing conditions such as diaper rash and atopic dermatitis are disclosed. The compositions and methods are particularly useful in the treatment and prevention of diaper rash and diaper dermatitis caused by the prolonged contact of human skin with body waste. The methods employ the topical application of a trypsin-inhibiting agent to the area in need of such treatment, or the area where prevention is desired. The trypsin-inhibiting agent is preferably zinc oxide in combination with an acid so as to release a specified divalent cation, i.e., zinc.
    Type: Application
    Filed: June 28, 2011
    Publication date: January 3, 2013
    Inventors: Connie B. Lin, Euen Thomas Graham Ekman Gunn, Ya-Ping Hu, Neema Kulkarni, Mary Catherine Mack, Selina Moses, Thong Huy Nguyen
  • Publication number: 20130004587
    Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 3, 2013
    Applicant: SCIESSENT LLC
    Inventor: Joseph J. Crudden
  • Publication number: 20130004588
    Abstract: Compositions and methods for treating and/or preventing conditions such as diaper rash and atopic dermatitis are disclosed. The compositions and methods are particularly useful in the treatment and prevention of diaper rash and diaper dermatitis caused by the prolonged contact of human skin with body waste. The methods employ the topical application of a trypsin-inhibiting agent to the area in need of such treatment, or the area where prevention is desired. The trypsin-inhibiting agent is preferably a divalent cation.
    Type: Application
    Filed: June 28, 2011
    Publication date: January 3, 2013
    Inventors: Connie B. Lin, Euen Thomas Graham Ekman Gunn, Ya-Ping Hu, Neema Kulkarni, Mary Catherine Mack
  • Patent number: 8343535
    Abstract: Disclosed are a hydrogel dressing for covering or treating a wound and a method for preparing the same. The hydrogel dressing includes a matrix structure of a cross-linked mixture, and an elastic sheet coated with an elementary metal or ionic metal embodied in the matrix structure. The mixture comprises a hydrophilic polymer, about 0.5 to about 5 wt % of a photocatalyst agent and at least 80 wt % of water based on the total weight of the mixture.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: January 1, 2013
    Assignee: The Chinese University of Hong Kong
    Inventors: Andrew Burd, Michael Wing Wai Tsang
  • Patent number: 8338130
    Abstract: This invention provides compositions and methods for fixing biological samples, particularly fecal samples used in the diagnosis of parasitic infection. The fixative composition of the present invention includes a zinc salt, an organic acid and water and permits staining of biological samples without use of toxic compounds, such as formaldehyde and mercury-containing compounds and without the use of additives such as polyvinyl alcohol. The fixative composition and methods are compatible with many diagnostic assays, including trichrome stains, iron hematoxlin, ELISA, fluorescent assays, and lateral flow assays.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: December 25, 2012
    Assignee: Medical Chemical Corporation
    Inventor: Andrew J. Rocha
  • Publication number: 20120316259
    Abstract: This invention relates to a process for the co-encapsulation of biocidally active ingredients in a clay mineral, the process comprising the step of bringing the clay mineral into contact with a biocidally active nitrogen compound that contains at least one hydrocarbon group with 6 to 20 carbon atoms, and at the same time or subsequently with at least one biocidally active compound selected from the group consisting of 2-n-octyl-4-isothiazoline-3-one, 3-iodopropenylbutyl-carbamate and tetrahis(hydroxymethyl)phosphonium sulfate. And the use of such encapsulated product in water based paints, coatings and varnishes.
    Type: Application
    Filed: February 15, 2011
    Publication date: December 13, 2012
    Applicant: CLARIANT S.A. BRAZIL
    Inventors: Antonio Pedro de Oliveira Filho, Wagner Claudio Da Silva, Manlio Gallotti, Alexandra Paschoalin Menezes, Karine Framesqui Righi, Marcia Regina Da Silva Rios
  • Publication number: 20120308630
    Abstract: Provided is a photocatalytic composition comprising zinc (Zn) doped titanium dioxide (TiO2) nanoparticles, wherein the ratio of titanium dioxide nanoparticles to zinc is from about 5 to about 150. The photocatalytic composition absorbs electromagnetic radiation in a wavelength range from about 200 nm to about 500 nm, and the absorbance of light of wavelengths longer than about 450 nm is less than 50% the absorbance of light of wavelengths shorter than about 350 nm. Further provided is a method for treating or preventing microbial diseases and infestations in a plant and a method for increasing crop yield of a plant by applying the photocatalytic compositions taught herein to the surface of a plant. Also provided is a method for treating microbial diseases on a surface by applying the photocatalytic compositions taught herein to a surface illuminated by artificial light.
    Type: Application
    Filed: May 3, 2012
    Publication date: December 6, 2012
    Inventors: Steward B. Averett, Devron R. Averett
  • Patent number: 8323630
    Abstract: The present invention is directed to the provision of multi-dose, self-preserved ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP), without requiring the presence of conventional anti-microbial preservative agents, such as benzalkonium chloride. The compositions are effectively preserved by a balanced ionic buffer system containing zinc ions at a concentration of 0.04 to 0.9 mM, preferably 0.04 to 0.4 mM. One aspect of the balanced buffer system is limitation of the amount of buffering anions present to a concentration of 15 mM or less, preferably 5 mM or less. In a preferred embodiment, the compositions also contain borate or, most preferably, one or more borate/polyol complexes. The use of propylene glycol as the polyol in such complexes is strongly preferred.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: December 4, 2012
    Assignee: Alcon Research, Ltd.
    Inventors: Bhagwati P. Kabra, Masood A. Chowhan, L. Wayne Schneider, Wesley Wehsin Han
  • Publication number: 20120301409
    Abstract: A homeopathic composition and method for treating a variety of skin irritations, wounds, and diseases is disclosed. The homeopathic composition may contain as active ingredients salicyclic acid, trona or one of its salts, and at least one homeopathic agent.
    Type: Application
    Filed: May 23, 2011
    Publication date: November 29, 2012
    Inventors: Ned L. Jensen, Peter E. Fuller
  • Patent number: 8317912
    Abstract: The present invention relates to an antimicrobial composition comprising an isothiazolin-3-one, such as 1,2-benzisothiazolin-3-one, a zinc compound selected from zinc salts, zinc oxide, zinc hydroxide or combinations thereof, a pyrithione salt or pyrithione acid, and a surfactant selected from the group consisting of (i) an anionic surfactant having a sulfate or sulfonate moiety attached to a straight or branched chain containing from about 10 to about 18 atoms at the backbone of the chain, (ii) an anionic surfactant being an alkylaryl sulfonic acid or salt thereof wherein the alkyl portion contains from about 10 to about 18 carbon atoms, and the aryl portion contains a benzyl or substituted benzyl group, and combinations thereof. This composition is particularly effective in preventing the growth of various microorganisms in mineral slurries such as aqueous calcium carbonate slurries.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: November 27, 2012
    Assignee: Arch Chemicals, Inc.
    Inventors: Helen Margaret Hyde, Fitzgerald Clarke, Helmut Peters, Terri Williams
  • Publication number: 20120294921
    Abstract: An antibacterial agent including a photocatalytic antibacterial material. The photocatalytic antibacterial material includes a rare-earth element modified tetrapod-shaped zinc oxide whisker (T-ZnOw). A method for preparation of the antibacterial agent is also provided, and includes: 1) adding a tetrapod-shaped zinc oxide whisker and a dispersant into a dispersion medium, and dispersing to yield a tetrapod-shaped zinc oxide whisker dispersion system; and 2) adding a rare-earth element to the dispersion system under ultrasound conditions, stirring, performing ultrasonic vibration, filtering, washing, drying, and baking, to yield the antibacterial agent.
    Type: Application
    Filed: July 27, 2012
    Publication date: November 22, 2012
    Inventors: Xiaozhong HUANG, Hongyu LONG, Ping XIANG, Yi YANG, Zuojuan DU, Liyu CHEN
  • Patent number: 8313767
    Abstract: Sustained release microparticles suitable for various types of drugs, or drug-containing sustained release microparticles capable of sustained release of drugs over a period of three days or more and capable of inhibiting initial burst release; a process for producing the same; and preparations containing the microparticles are disclosed. The drug-containing sustained release microparticles comprise a drug other than human growth hormone and a porous apatite derivative, and optionally include a water-soluble bivalent metal compound.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: November 20, 2012
    Assignee: Independent Administrative Institution, National Institute for Materials Science
    Inventors: Yutaka Mizushima, Yasuaki Ogawa, Junzo Tanaka, Toshiyuki Ikoma
  • Publication number: 20120282645
    Abstract: Nanoparticles, compositions comprising the nanoparticles, and methods for manufacture and uses thereof are provided. In at least one specific embodiment, the nanoparticle can include at least one isotopically enriched metal oxide. The isotopically enriched metal oxide can be copper or zinc.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 8, 2012
    Applicant: NATURAL HISTORY MUSEUM
    Inventors: Superb K. Misra, Agnieszka Dybowska, Deborah Berhanu, Eugenia Valsami-Jones
  • Publication number: 20120276218
    Abstract: A biocompatible composition for tissue repair or regeneration in mammals comprising one or more glass former compounds selected from the group consisting of B2O3, P2O5, and SiO2 and director elements selected from the group consisting of Cu, Sr, Zn, Fe, Mn, Cr, V, Nb, Mo, W, Ba, Co, S, Al, Ti, Y, Mg, Si and/or Ni to promote in vivo calcium compound formation of calcium carbonate or other calcium compounds other than hydroxyapatite. Upon direct application of the biocompatible composition to a mammalian host, calcium carbonate or other calcium compounds other than hydroxyapatite form upon bioreaction of the composition with bodily fluids.
    Type: Application
    Filed: July 6, 2012
    Publication date: November 1, 2012
    Applicant: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: Steven B. Jung, Delbert E. Day
  • Publication number: 20120276219
    Abstract: Antimicrobial compositions having a rapid antiviral and antibacterial effectiveness, and a persistent antiviral effectiveness, are disclosed. The anti-microbial compositions contain (a) an antimicrobial agent, (b) a disinfecting alcohol, and (c) (i) an organic acid, (ii) an inorganic salt comprising a cation having a valence of 2, 3, or 4 and a counterion capable of lowering a surface pH to about 5 or less, (iii) an aluminum, zirconium, or aluminum-zirconium complex, or (iv) mixtures thereof, wherein the composition has a pH of about 5 or less.
    Type: Application
    Filed: July 9, 2012
    Publication date: November 1, 2012
    Applicant: THE DIAL CORPORATION
    Inventors: Timothy J. Taylor, Priscilla S. Fox, Earl P. Seitz, JR.
  • Publication number: 20120276165
    Abstract: The present invention provides a composition comprising an acidified aqueous solution of (1) micro colloidal silicic acid, (2) boric acid, and (3) a water absorbing additive, having a pH value of equal to or less than 1, wherein the micro colloidal silicic acid has particle sizes in the range of 1-8 nm, especially in the range of 1.5-6 nm. The invention also provides a particulate product obtainable by the method according to claim 18, wherein the particles comprise (1) silicic acid, (2) boric acid, and (3) the water absorbing additive, and wherein at least 90% of the particles in the particulate product have particle sizes in the range of 0.3-5 ?m.
    Type: Application
    Filed: December 8, 2010
    Publication date: November 1, 2012
    Inventors: Henk Maarten Laane, Walter Ferdinand Witterland
  • Patent number: 8293257
    Abstract: An oily dispersion of an inorganic microparticle oxide powder that exhibits excellent texture has superior compatibility with other cosmetic material components. The oily dispersion contains only two components of a dispersion medium and a surface-treated inorganic microparticle oxide powder, wherein the dispersion medium is an oil, the surface-treated inorganic microparticle oxide powder is a powder surface-treated with branched fatty acid containing isostearic acid as a primary constituent component or a metal salt containing isostearic acid as a primary constituent component at an amount of 1 to 30% by weight with respect to the powder as a base material, and the surface-treated inorganic microparticle oxide powder has a solid concentration of 25% by weight or more and a viscosity of 2,000 mPa·s or less at 25° C. in the preparation of the oily dispersion.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: October 23, 2012
    Assignee: Tayca Corporation
    Inventors: Kazunori Yagi, Naoki Kanda
  • Patent number: 8287893
    Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: October 16, 2012
    Assignee: Sciessent LLC
    Inventor: Joseph J. Crudden
  • Publication number: 20120258168
    Abstract: Embodiments include a composition to promote ocular health and a method of treatment for a subject exposed to a source of oxidative or visual stress to the eye or having a degradation of the eye. The composition may include amounts of vitamin A, which includes beta-carotene; vitamin C; vitamin D; vitamin E; zinc; copper; selenium; non-vitamin A carotenoids, which include lutein and zeaxanthin; omega-3 fatty acids, which include eicosapentaenoic acid and docosahexaenoic acid; taurine; alpha lipoic acid; pine bark extract; astaxanthin; and Piper spp. extract. The method includes the step of administering to the subject a daily dose of a composition to promote ocular health.
    Type: Application
    Filed: April 9, 2012
    Publication date: October 11, 2012
    Applicant: AMERISCIENCES, LP
    Inventor: Carlos A. Montesinos
  • Patent number: 8282951
    Abstract: Antimicrobial coatings to protect surfaces and a method of applying such a coating are disclosed. An antimicrobial coating may be applied to a surface, such as the interior surface of a building's exterior wall. The interior surface must be accessed, and then an antimicrobial coating is provided and applied. The antimicrobial coating includes an inorganic antimicrobial additive and a colloidal polymeric medium. The inorganic antimicrobial additive may be silver, platinum, gold, palladium, copper, zinc, boron, or a compound of any of those elements. By including an ultraviolet tracer or color dye additive in the coating, it is possible to detect the coating at any time, provided that the surface is accessed.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: October 9, 2012
    Assignee: EnviroCare Corporation
    Inventor: Bryan M. Redler
  • Patent number: 8282949
    Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising metal-acid solutions.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: October 9, 2012
    Assignee: Sciessent LLC
    Inventor: Joseph J. Crudden
  • Publication number: 20120251627
    Abstract: The present invention is directed to an antimicrobial composition, comprising pyrithione or a pyrithione complex; and a zinc or copper or silver source selected from the group consisting of zinc or copper or silver salts, oxides, hydroxides, sulfates, chlorides, metals, and combinations thereof; wherein the weight ratio of the zinc or copper or silver source to the pyrithione or the pyrithione complex is in the range from about 1:300 to about 50:1, and wherein the antimicrobial composition has an enhanced biocidal effect against a variety of free-living microorganisms or biofilms. Also disclosed is a method of inhibiting the growth of free-living microorganisms or biofilm utilizing the above antimicrobial composition, as well as use of such antimicrobial compositions in various products including fuels, fluids, lubricants, coatings, adhesives, sealants, elastomers, soaps, cosmetics, plastic or woven or non-woven fibers, pharmaceuticals, and as preservatives for the above products.
    Type: Application
    Filed: June 14, 2012
    Publication date: October 4, 2012
    Inventors: John D. Nelson, Thomas J. Palys, Jon R. Geiger
  • Publication number: 20120247364
    Abstract: The present invention relates to an antimicrobial composition comprising an isothiazolin-3-one, such as 1,2-benzisothiazolin-3-one, a zinc compound selected from zinc salts, zinc oxide, zinc hydroxide or combinations thereof, a pyrithione salt or pyrithione acid, and a surfactant selected from the group consisting of (i) an anionic surfactant having a sulfate or sulfonate moiety attached to a straight or branched chain containing from about 10 to about 18 atoms at the backbone of the chain, (ii) an anionic surfactant being an alkylaryl sulfonic acid or salt thereof wherein the alkyl portion contains from about 10 to about 18 carbon atoms, and the aryl portion contains a benzyl or substituted benzyl group, and combinations thereof. This composition is particularly effective in preventing the growth of various microorganisms in mineral slurries such as aqueous calcium carbonate slurries.
    Type: Application
    Filed: March 9, 2012
    Publication date: October 4, 2012
    Inventors: Helen Margaret Hyde, Fitzgerald Clarke, Helmut Peters, Terri Williams
  • Publication number: 20120251450
    Abstract: Of the many compositions and methods provided herein, one composition includes a nanoparticle having a first oxide of a first metal and a dopant that includes an ion or an atom of a second metal. A method includes a method comprising providing a plurality of nanoparticles comprising a first oxide of a first metal and a dopant that comprises an ion or an atom of a second metal; providing a diseased cell and a healthy cell; contacting the diseased cell and the healthy cell with the nanoparticle; and allowing the nanoparticle to preferentially associate with the diseased cell.
    Type: Application
    Filed: April 4, 2011
    Publication date: October 4, 2012
    Inventors: Alex Punnoose, Denise Wingett
  • Patent number: 8277829
    Abstract: A biocompatible inorganic porous material having a three-dimensional coexistent network of interconnected macro-pores and nanopores produced by the steps of mixing an organic water-soluble polymer (e.g., polyethylene oxide or a block copolymer of ethylene oxide and propylene oxide), an alkoxysilane, and an inorganic water-soluble calcium salt in an aqueous acid solution, such that a sol-gel process of hydrolysis and polycondensation is initiated and thereby producing a gel; drying the gel to remove solvent by evaporation; and heating the gel to remove the polymer by thermal decomposition, thereby forming an inorganic porous material, which may be suitable for use as a bone tissue scaffold.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: October 2, 2012
    Assignee: Lehigh University
    Inventors: Himanshu Jain, Ana C. Marques, Rui M. Almeida
  • Patent number: 8273381
    Abstract: A composition, system and method for modifying an olfactory response to an odorant is disclosed. In some embodiments, the composition includes crystalline metal nanoparticles dispersed in an aqueous medium. The composition is applied to olfactory tissues using a suitable applicator or dispenser. The metal nanoparticles are believed to interact with a G-protein coupled to receptor located in the cilia to moderate (enhance or reduce) sensitivity or ability to smell particular odorants. In accordance with an embodiment of the invention, the composition includes one or more odorants.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: September 25, 2012
    Assignee: Auburn University
    Inventors: Vitaly J. Vodyanoy, Lewis G. Scharpf, Jr., Alexandre Samoylov, Nilmini Viswaprakash, Ludmila Petrovna Globa, Edward E. Morrison
  • Patent number: 8268299
    Abstract: The present invention is directed to the provision of multi-dose, self-preserved ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP), without requiring the presence of conventional anti-microbial preservative agents, such as benzalkonium chloride. The compositions are effectively preserved by a balanced ionic buffer system containing zinc ions at a concentration of 0.04 to 0.9 mM, preferably 0.04 to 0.4 mM. One aspect of the balanced buffer system is limitation of the amount of buffering anions present to a concentration of 15 mM or less, preferably 5 mM or less. In a preferred embodiment, the compositions also contain borat or, most preferably, one or more borate/polyol complexes. The use of propylene glycol as the polyol in such complexes is strongly preferred.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: September 18, 2012
    Assignee: Alcon Research, Ltd.
    Inventors: Bhagwati P. Kabra, Masood A. Chowhan, L. Wayne Schneider, Wesley Wehsin Han
  • Patent number: 8268363
    Abstract: The invention relates to the application of a combination including all forms of zinc or zinc substances, at least one of an orally applied combination of a free thiol group or a group that is metabolized to a free thiol in a mammal, and as the only pure plant part, glycyrrhicinic acid or the substance from succus liquiritiae, for the production of a medication to fight acute or chronic viral infections. The free thiol group or the group that is metabolized to a free thiol in a mammal is derived from N-acetylcysteine, methionine, cysteine, allylcysteine, alpha lipoic acid, or sulfur.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: September 18, 2012
    Inventor: Dana Flavin-Koenig
  • Patent number: 8263667
    Abstract: A nutritional supplement for use in physiologically stressful conditions is disclosed. The nutritional supplement may include one or more of vitamin A, vitamin E, vitamin D3, vitamin C, vitamin B1, riboflavin, niacin, folic acid, vitamin B6, biotin, pantothenic acid, vitamin B12, magnesium, zinc, selenium, chromium, copper, iron, alpha lipoic acid, lutein and lycopene.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: September 11, 2012
    Assignee: Vertical Pharmaceuticals, Inc.
    Inventors: Steven A. Squashic, Kevin M Hudy, David C. Purdy