Chloride Patents (Class 424/663)
  • Patent number: 10729721
    Abstract: The present invention relates to a medical solution. According to the invention the ready-for-use solution comprises phosphate in a concentration of 1.0-2.8 mM, is sterile and has a pH of 6.5-7.6. The present invention further relates to a method for producing the medical solution and the use thereof.
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: August 4, 2020
    Assignee: Gambro Lundia AB
    Inventors: Ola Carlsson, Malin Ernebrant, Gunita Forsbäck, Anders Wieslander, Therese Svensson
  • Patent number: 10253371
    Abstract: A method of treating leukemia in a patient, the method including obtaining a plasma sample from a patient at a first time point and at a second time point, measuring a gene expression level of a set of core clock genes, and at least one of a first set of peripheral clock genes and a second set of peripheral clock genes, each in the plasma sample at the first time point and in the plasma sample at the second time point. Then determining that a first treatment is effective or ineffective for the patient when a correlation of the gene expression level of the set of core clock genes, the first set of peripheral clock genes, and the second set of peripheral clock genes, and treating the patient accordingly.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: April 9, 2019
    Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
    Inventors: Mohamed Boudjelal, Ahmed Al Askar, Alshaimaa Alhallaj, Atef Nehdi, Hina Rehan, Sabhi Rahman, Gamal Edin Gmati, Khadega A. Abuelgasim
  • Patent number: 9687506
    Abstract: Provided herein are pharmaceutically acceptable sodium nitrite and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-volatile organic carbon in a sodium nitrite-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium nitrite. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium nitrite.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: June 27, 2017
    Assignee: Hope Medical Enterprises, Inc.
    Inventors: Craig Sherman, Anthony James Lepine, Catherine Marie Smith, Kevin Robert Wirtz, Erich Schulze
  • Patent number: 9682128
    Abstract: An aqueous composition for application in a method for surgical or therapeutic treatment of the human or animal body or in a diagnostic procedure which is practiced on the human or animal body, the composition comprising osmotically active particles and containing less than 70 ?l?1 of amniotic cells, the osmolarity of the composition being in the range from 240.0 mosm/l to less than 308.0 mosm/l, and the chloride ion concentration in the composition being not more than 130.0 mmol/l. An aqueous composition for application with an amniotic infusion, the composition containing less than 70 ?l?1 of amniotic cells and comprising at least one surfactant, is also disclosed.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: June 20, 2017
    Inventor: Michael Tchirikov
  • Patent number: 9072755
    Abstract: An aqueous composition for application in a method for surgical or therapeutic treatment of the human or animal body or in a diagnostic procedure which is practiced on the human or animal body, the composition comprising osmotically active particles and containing less than 70 ?l?1 of amniotic cells, the osmolarity of the composition being in the range from 240.0 mosm/l to less than 308.0 mosm/l, and the chloride ion concentration in the composition being not more than 130.0 mmol/l. An aqueous composition for application with an amniotic infusion, the composition containing less than 70 ?l?1 of amniotic cells and comprising at least one surfactant, is also disclosed.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: July 7, 2015
    Inventor: Michael Tchirikov
  • Publication number: 20150140127
    Abstract: Provided is a method for detecting injury to the brain comprising: a) determining the level of a tight junction (TJ) protein in exosomes isolated from a test sample from a subject, wherein the TJ protein is occludin, claudin-3, claudin-5, claudin-12, ZO-1, ZO-2, ZO-3, JAM-A, JAM-B or JAM-C, or any combination thereof; b) comparing the level of the TJ protein in the test sample to the level of the TJ protein in a control sample, wherein an elevated level of the TJ protein in the test sample relative to the level of the TJ protein in the control sample indicates that the subject has an injury to the brain.
    Type: Application
    Filed: June 25, 2013
    Publication date: May 21, 2015
    Applicant: TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Servio H. Ramirez, Slava Rom, Yuri Persidsky
  • Publication number: 20150104527
    Abstract: The invention relates to an aqueous ionic solution, particularly for nasal use, including: at least one seawater solution having an osmolality of between 290 mOsm/kg and 400 mOsm/kg in a weight proportion of between about 30 and 98 wt % relative to the total weight of the composition; at least one cationic phospholipid of natural origin in a weight proportion of between about 0.01 and 5 wt % relative to the total weight of the composition; and at least one compound, which is originally immiscible with said seawater solution, in a weight proportion of between 0.01 and 10 wt % relative to the total weight of the composition.
    Type: Application
    Filed: February 2, 2012
    Publication date: April 16, 2015
    Applicant: LABORATOIRE DE LA MER
    Inventors: Francois Andro, Anne Beaulieu
  • Patent number: 9005671
    Abstract: This invention provides concentrated aqueous biocidal solutions formed from bromine chloride, sodium hydroxide, and sulfamic acid. The weight ratio of bromine chloride:sodium hydroxide:sulfamic acid used in forming the concentrated solution is such that for every 10.5 to 11.5 parts by weight of bromine chloride used, 15.3 to 17.5 parts by weight of sodium hydroxide and 11.0 to 12.5 parts by weight of sulfamic acid are used, the biocidal solution containing at least about 100,000 ppm (wt/wt) of active bromine based on the total weight of the solution.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: April 14, 2015
    Assignee: Albemarle Corporation
    Inventor: Farah D. Azarnia
  • Publication number: 20150079200
    Abstract: The present invention relates to systems and methods for generating germicidal compositions for use in a wide variety of settings, including agricultural settings (e.g., animal bedding), food production settings, hospitality settings, health care settings, health club settings, exercise facility settings, research based settings, veterinarian settings, medical settings, hydraulic fracturing settings, and/or any setting requiring disinfection.
    Type: Application
    Filed: November 5, 2014
    Publication date: March 19, 2015
    Inventors: Carmine J. Durham, R. Andrew Morgan, Michael C. Pawlak
  • Patent number: 8968758
    Abstract: The present invention provides a method for preparing a material in the form of liquid for forming an antimicrobial surface coating with multi-level antimicrobial properties, comprising: encapsulating one or more volatile or gaseous biocides in two or more amphiphilic block copolymers to obtain a w/o/w double emulsion, and mixing the w/o/w double emulsion with one or more nonvolatile biocides, each of which is selected from the group consisting of a metal containing biocide, triclosan, a carboxylic acid, a sugar acid and a combination thereof.
    Type: Grant
    Filed: April 15, 2014
    Date of Patent: March 3, 2015
    Assignee: The Hong Kong University of Science and Technology
    Inventors: King Lun Yeung, Wai Kin Leung
  • Publication number: 20150056303
    Abstract: The present invention is directed to a method, system and equipment for the elaboration of electrolytic chlorine oxidants, hypochlorous acid and sodium hypochlorite substances, using elements that result in an ecological process and confers a high efficiency in the production of these substances, permitting the generation of a product of very high performance and efficiency.
    Type: Application
    Filed: August 23, 2013
    Publication date: February 26, 2015
    Inventors: Miguel Angel Alcantara, Adan Tapia Duran
  • Publication number: 20150056304
    Abstract: A gel, in particular for use in a wound treatment agent includes an inorganic silicate as thickener; and an electrochemically activated aqueous common salt solution having a content of free chlorine of more than 200 mg/l and a conductivity of not more than 12 mS/cm.
    Type: Application
    Filed: July 6, 2012
    Publication date: February 26, 2015
    Inventor: Hans-Georg Mathé
  • Publication number: 20150044300
    Abstract: An aqueous biocidal composition comprising a mixture of hydrochloric acid (HCl), urea, and sodium hypochlorite (NaOCl) at acidic pH, a method for manufacturing the composition and a biocidal technology for treating industrial water.
    Type: Application
    Filed: March 19, 2013
    Publication date: February 12, 2015
    Inventors: Shlomo Antebi, David Feldman, Chen Zolkov
  • Publication number: 20150030701
    Abstract: Disclosed are compositions and methods for antimicrobial use. The compositions contain a small antimicrobial agent and a permeabilizing agent. The antimicrobial compositions can be antifungal or antibacterial compositions.
    Type: Application
    Filed: March 13, 2013
    Publication date: January 29, 2015
    Applicant: Yale University
    Inventors: Ronald R. Breaker, Sanshu Li
  • Publication number: 20140370123
    Abstract: A skin external composition comprising a combination of salt and sugar as an active ingredient in an amount effective to treat and prevent vaginosis, together with a pharmaceutically acceptable carrier, and the use thereof.
    Type: Application
    Filed: August 5, 2014
    Publication date: December 18, 2014
    Inventors: Won Seog CHOI, Dong-Yeul KWON
  • Publication number: 20140257514
    Abstract: A bone graft substitute in the form of an implantable three-dimensional scaffold that includes calcium phosphate and has pores. The scaffold is impregnated with a calcium and/or phosphate containing substance, and the dissolution rate DRS of the scaffold is slower than the dissolution rate DRD of the calcium and/or phosphate containing substance.
    Type: Application
    Filed: May 21, 2014
    Publication date: September 11, 2014
    Applicant: Mathys AG Bettlach
    Inventors: Marc Bohner, Reto Luginbühl
  • Patent number: 8828232
    Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: September 9, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Dilip H. Shah, Todd Ing
  • Patent number: 8808774
    Abstract: The described pKa process creates a unique combination of active ingredients. The calcium carbonate carrier is impregnated with various proportions of active ingredients and the compounds are made more effective by the sheer and absorption action as they are combined in the described process. The calcium carrier is adjusted to incorporate small amounts of highly efficient/effective pH adjusters. No natural solution exists in Nature with a pH of 10.6 that is optimal for adjusting the pKa naturally in foods. The present invention effects a change in the pKa of most acids and therefore impacts pH which can positively affect flavor, color and taste. The reduced moisture process in combination with the invention solution applied as a treatment results in fruits and vegetables that exhibit cleaner flavors, better texture, enhanced color and lower microbial counts than is found in standard IQF vegetables currently available.
    Type: Grant
    Filed: June 17, 2006
    Date of Patent: August 19, 2014
    Assignee: Scientific Food Solutions, LLC
    Inventors: Ricky L. Falkenberg, Harold L. Archibald, Danford Wilkinson, Lisa L. Trexler
  • Patent number: 8741325
    Abstract: The present invention provides a material for forming an antimicrobial surface coating with multi-level antimicrobial properties, which comprises one or more volatile or gaseous biocides, one or more nonvolatile biocides, and one or more polymers, wherein the volatile or gaseous biocides are encapsulated in the polymers to provide a sustained release of the volatile or gaseous biocides. The present invention further provides a method for preparing the material.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: June 3, 2014
    Assignee: The Hong Kong University of Science and Technology
    Inventors: King Lun Yeung, Wai Kin Leung
  • Publication number: 20140141101
    Abstract: The present invention relates to ionic compositions for enhancing wound healing, particularly in the sinonasal cavity. The ionic components of the composition can include potassium, calcium, rubidium, zinc, bromide, and magnesium in an isotonic solution. In other embodiments, the ionic components of the composition can include magnesium, bromide, sulfate, sodium, and chloride. Methods of enhancing wound healing, enhancing sinonasal mucosal healing, promoting mucosal reciliation, and debriding tissue by administering the compositions of the present invention are also presented.
    Type: Application
    Filed: January 23, 2014
    Publication date: May 22, 2014
    Applicant: Red Oax Holdings, LLC
    Inventor: Kevin Powers
  • Publication number: 20140093586
    Abstract: Disclosed are oral rehydration compositions with sucrose, or alternatively fructose and glucose in a 1:1 ratio. The compostion further comprises an osmolarity of below 250 mOsm/L, and sodium below 75 meq/L. Further disclosed are methods of treatment using the same.
    Type: Application
    Filed: September 24, 2013
    Publication date: April 3, 2014
    Applicant: Drip Drop, Inc.
    Inventor: Eduardo P. DOLHUN
  • Patent number: 8679548
    Abstract: Described are highly concentrated liquid biocidal solutions formed in water from (a) specified bromine sources (e.g., BrCl or mixtures of BrCl and Br2) and (b) alkali metal salt of sulfamic acid and/or sulfamic acid and alkali metal base, wherein the solution contains >160,000 ppm of active bromine. Solutions of this type have been found to have greater stability than a commercially-available solution made from the same components containing 148,600 ppm of active bromine. Also described are new, water-soluble, solid state biocidal products formed by removing the water from solutions made in water from (a) and (b) irrespective of the initial concentration of active bromine. Removal of water can be accomplished by flashing or distillation at reduced pressure or preferably by spray drying. Such solid state products are typically in the form of powders or small particles, but can be compacted into larger forms preferably with the aid of one or more suitable binding agents.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: March 25, 2014
    Assignee: Albemarle Corporation
    Inventors: Christopher J. Nalepa, Robert M. Moore, Jr.
  • Publication number: 20140072522
    Abstract: The invention relates to the use, in a cosmetic or dermatological composition, of a particular water having a pH of between 7.8 and 10 and a total dissolved solids (TDS) concentration of between 10 and 250 mg/l. The invention also relates to a cosmetic or dermatological composition containing this water. The invention relates in particular to a treatment method intended for preventing or delaying the appearance of the effects of intrinsic and/or extrinsic ageing of the skin, or for slowing down the effects thereof; for preventing or reducing pigmentary spots on the skin, or the coloration of hyperpigmented areas of skin; for reducing the pigmentation of the periphery of depigmented areas; for improving the uniformity of the skin coloration; or for lightening the complexion of the skin.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 13, 2014
    Applicant: LVMH RECHERCHE
    Inventors: Robin KURFURST, Kristell LAZOU, Eric PERRIER
  • Publication number: 20130295200
    Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.
    Type: Application
    Filed: April 5, 2013
    Publication date: November 7, 2013
    Inventor: Nuvo Research AG
  • Patent number: 8574605
    Abstract: The invention includes convenient methods of preparing: (1) highly concentrated liquid bromine-containing biocidal solutions, (2) highly concentrated mixed halogen liquid bromine and chlorine-containing biocidal solutions, and (3) high-activity bromine-containing biocidal solids, all having excellent physical and chemical stability. One method yields solutions that have concentrations of bromine in excess of 18% as Br2 (8% as Cl2) in which the mole ratio of hydroxide ion to hydrogen ion source is at least 1.9:1. Another method employs elemental bromine in conjunction with a solid organic or inorganic halogenating agent to yield halogen solutions at concentrations greater than 22.9% as Br2 (10.2% as Cl2). This method can be performed under conditions that exceed the solubility of the active ingredient such that it crystallizes and is recovered as a hydrated or anhydrous salt in good yield.
    Type: Grant
    Filed: October 19, 2007
    Date of Patent: November 5, 2013
    Assignee: Enviro Tech Chemical Services, Inc.
    Inventors: Jonathan N. Howarth, Michael S. Harvey
  • Patent number: 8568759
    Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 29, 2013
    Assignee: W. Neudorff GmbH KG
    Inventor: Diana L. Parker
  • Publication number: 20130280346
    Abstract: Normal saline and other infusate solutions for infusion into the body of a patient during medical treatment are disclosed. In particular, infusates are disclosed that are formulated to resist changes to the pH of the solution when subjected to sterilization procedures that employ ethylene oxide gas. In one embodiment, a buffered infusate suitable for disposal in a syringe or other container is disclosed. The syringe is sterilizable using ethylene oxide. The buffered infusate comprises an aqueous solution that is disposed in the syringe and is suitable for infusion into a body of a patient. A buffer component is added to the aqueous solution to form a buffered solution. The buffer component is configured to resist a change in the pH of the buffered solution upon exposure of the buffered solution to the ethylene oxide during sterilization of the syringe.
    Type: Application
    Filed: April 19, 2013
    Publication date: October 24, 2013
    Applicant: C. R. BARD, INC.
    Inventors: Kelly B. Powers, Murtaza Yusuf Amin, Matthew R. Trebella, James L. Freasier, Raymond Kerns
  • Patent number: 8557299
    Abstract: An improved dietary and/or therapeutic supplement composition comprising a quantity of a dietary and/or therapeutic supplement agent having a pH that upon ingestion with food or a beverage would limit the effectiveness of the agent and a sufficient amount of an alkaline electrolyte additive is provided in combination with the agent to raise the pH of the composition to a level of from about 8 to about 12.5 to increase the effectiveness and functional utilization of the agent while the composition is in the person's stomach. In a preferred composition, the electrolyte additive is selected from the group consisting of calcium, magnesium and potassium electrolytes. The supplement composition may be in the form of tablet, capsule, powder or liquid forms. The supplement composition is designed to provide for optimum utilization of a dietary and/or therapeutic supplement agent when taken orally with food or a beverage.
    Type: Grant
    Filed: October 30, 2012
    Date of Patent: October 15, 2013
    Inventors: Janmarie Hornack, Lawrence E. Dorman
  • Patent number: 8557301
    Abstract: Disclosed are oral rehydration compositions with sucrose, sodium, chloride, and citric acid or citrate. The composition further comprises an osmolarity of below 250 mOsm/L, and sodium below 75 meq/L. Further disclosed are methods of treatment using the same.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: October 15, 2013
    Assignee: Drip Drop, Inc.
    Inventor: Eduardo P. Dolhun
  • Publication number: 20130266667
    Abstract: The present invention relates to a pharmaceutical combination for the treatment of renal failure in pets, caused by various diseases or ineffective to traditional renal therapy or renal replacement therapy thereby incapable of restoring health. The pharmaceutical combination of the present invention is administered by subcutaneous injection to pets in need thereof, with various advantages including simple use, no requirement for surgery, hospitalization and/or fluid infusion, faster recovery of health status, reduced medical costs, significantly improved recovery rate, reduced mortality and the likes. The pharmaceutical combination of the present invention can also be used for the continuous care treatment of pets with renal failure.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 10, 2013
    Inventor: Cheng Yi LIN
  • Publication number: 20130236570
    Abstract: The optimum concentration of salt in solutions to combat congestion of the mucosa is a relatively narrow range. This use of in hypertonic saline solutions for treatment of congestion of the mucosa having a concentration within the range of 2.3% to 2.7% w/v sodium chloride/water with the most preferred concentration being 2.4% to 2.6% w/v of sodium chloride in water brings maximum relief of congestion without causing irritation or discomfort.
    Type: Application
    Filed: March 9, 2012
    Publication date: September 12, 2013
    Inventor: Matthew Lutin
  • Publication number: 20130156867
    Abstract: The present invention relates to an oil-in-water emulsion comprising at least one mucomimetic polymer, at least one lipid of phospholipid type, at least one lipid other than the phospholipid, at least one stabilizing polymer, and a hydrophilic liquid, to an emulsion comprising an aqueous phase that contains at least one stabilizing polymer and at least one mucomimetic polymer, and an oily phase that contains at least one lipid of phospholipid type and a lipid other than the phospholipid, to a medicament comprising one of these emulsions, and to the use of one of these emulsions as an agent for restoring and/or replacing the lachrimal film or as a carrier for an active compound.
    Type: Application
    Filed: April 21, 2011
    Publication date: June 20, 2013
    Applicant: HORUS PHARMA
    Inventors: Claude Claret, Martine Claret, Carole Gard, Nicola Lamprecht-Weissenborn
  • Patent number: 8414932
    Abstract: Described are highly concentrated liquid biocidal solutions formed in water from (a) specified bromine sources (e.g., BrCl or mixtures of BrCl and Br2) and (b) alkali metal salt of sulfamic acid and/or sulfamic acid and alkali metal base, wherein the solution contains >160,000 ppm of active bromine. Solutions of this type have been found to have greater stability than a commercially-available solution made from the same components containing 148,600 ppm of active bromine. Also described are new, water-soluble, solid state biocidal products formed by removing the water from solutions made in water from (a) and (b) irrespective of the initial concentration of active bromine. Removal of water can be accomplished by flashing or distillation at reduced pressure or preferably by spray drying. Such solid state products are typically in the form of powders or small particles, but can be compacted into larger forms preferably with the aid of one or more suitable binding agents.
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: April 9, 2013
    Assignee: Albemarie Corporation
    Inventors: Christopher J. Nalepa, Robert M. Moore, Jr.
  • Patent number: 8414768
    Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: April 9, 2013
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Dilip H. Shah, Todd Ing
  • Publication number: 20120330436
    Abstract: A bone graft substitute in the form of an implantable three-dimensional scaffold that includes calcium phosphate and has pores. The scaffold is impregnated with a calcium and/or phosphate containing substance, and the dissolution rate DRS of the scaffold is slower than the dissolution rate DRD of the calcium and/or phosphate containing substance.
    Type: Application
    Filed: March 9, 2010
    Publication date: December 27, 2012
    Applicant: MATHYS AG BETTLACH
    Inventors: Marc Bohner, Reto Luginbuhl
  • Publication number: 20120325687
    Abstract: A low pH wipe is produced having no other buffering or modifying agents, using water only. The water has been modified by means of a reactor to produce an excess of hydronium ions to lower the pH.
    Type: Application
    Filed: June 21, 2012
    Publication date: December 27, 2012
    Inventors: Kent Scott, Craig Mortensen
  • Publication number: 20120294849
    Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.
    Type: Application
    Filed: July 27, 2012
    Publication date: November 22, 2012
    Inventors: Mathias Brosz, FRIEDRICH WILHELM KUHNE, KLAUS BLASZKIEWITZ, THOMAS ISENSEE
  • Patent number: 8298588
    Abstract: An improved dietary and/or therapeutic supplement composition comprising a quantity of a dietary and/or therapeutic supplement agent having a pH that upon ingestion with food or a beverage would limit the effectiveness of the agent and a sufficient amount of an alkaline electrolyte additive is provided in combination with the agent to raise the pH of the composition to a level of from about 8 to about 12.5 to increase the effectiveness and functional utilization of the agent while the composition is in the person's stomach. The supplement composition is designed to provide for optimum utilization of a dietary and/or therapeutic supplement agent when taken orally with food or a beverage.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: October 30, 2012
    Inventors: Janmarie Hornack, Lawrence E. Dorman
  • Publication number: 20120251631
    Abstract: Provided is a method for treating or preventing peritonitis by administering a therapeutically effective amount of an oxidative reduction potential (ORP) water solution that is stable for at least about twenty-four hours. The ORP water solution administered in accordance with the invention can be combined with one or more suitable carriers and can be administered in conjunction with one or more additional therapeutic agents. Further provided is a method for preventing peritoneal hemorrhage, adhesions and abscesses.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 4, 2012
    Applicant: OCULUS INNOVATIVE SCIENCES, INC.
    Inventors: Hojabr ALIMI, Andres Gutierrez
  • Publication number: 20120207853
    Abstract: The present invention provides methods of treating, reducing, and/or preventing the incidence of an influenza related viral infection in a patient comprising administering a therapeutically effective amount of an oxidative reductive potential (ORP) water solution. The present invention also provides methods of reducing or preventing the incidence of an influenza related viral infection in a patient associated with a medical device comprising contacting the medical device with an effective amount of an ORP water solution.
    Type: Application
    Filed: May 10, 2010
    Publication date: August 16, 2012
    Applicant: OCULUS INNOVATIVE SCIENCES, INC.
    Inventors: Hojabr Alimi, Eileen Thatcher
  • Publication number: 20120189709
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 26, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Publication number: 20120177744
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 12, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Patent number: 8216172
    Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolytes but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: July 10, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Peter C. Chang, Jean-Michel Lannoy
  • Publication number: 20120156313
    Abstract: Corrosion inhibitor compositions and methods of use are disclosed. Sugar acids and calcium corrosion inhibitors combined with hypochlorite sources provide use solutions for effective corrosion inhibition for metal surfaces.
    Type: Application
    Filed: November 9, 2011
    Publication date: June 21, 2012
    Applicant: ECOLAB USA INC.
    Inventors: Kim R. Smith, Erik C. Olson, Steven E. Lentsch
  • Patent number: 8202547
    Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.
    Type: Grant
    Filed: January 17, 2011
    Date of Patent: June 19, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Dilip H. Shah, Todd Ing
  • Patent number: 8178120
    Abstract: Methods for processing substrate surfaces carrying coatings comprising a metal are disclosed. The methods involve providing a substrate surface having a coating comprising a metal, and exposing the substrate surface to a mixture including an oxidizing agent and an anion.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: May 15, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Nathan A. Vandesteeg, John-Bruce D. Green, Vadim V. Krongauz, Phillip W. Carter, Dustin C. Cawthon
  • Patent number: 8158157
    Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolites but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: April 17, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Peter C. Chang, Jean-Michael Lannoy
  • Patent number: 8147855
    Abstract: Methods for inhibiting sensory responses in the skin such as pain and itch using topical formulations containing aqueous-soluble divalent strontium cation in a suitable topical keratinized skin formulation vehicle are disclosed.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: April 3, 2012
    Assignee: Cosmederm Bioscience, Inc.
    Inventors: Gary S. Hahn, David O. Thueson
  • Publication number: 20120052136
    Abstract: The present invention relates to isolated haemoglobin from worms belonging to the Nereididae family and its use in cell culture medium, in preservation solutions and as artificial oxygen carrier for transfusion.
    Type: Application
    Filed: May 7, 2010
    Publication date: March 1, 2012
    Applicant: HEMARINA
    Inventors: Morgane Rousselot, Delphine Dutheil, Franck Zal
  • Patent number: 8124059
    Abstract: The present invention describes a method and compositions by which introducing PO4?3 ion at particular stage in the preparation of aluminum/zirconium solutions surprisingly results in significantly improved zirconium molecular weight stability.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: February 28, 2012
    Assignee: Summit Research Labs, Inc.
    Inventors: Thomas L. Harper, Allan Rosenberg, Shailesh Mehta