Iodide Patents (Class 424/669)
  • Publication number: 20150147400
    Abstract: The invention is a solid oral dosage form that is designed to deliver a supraphysiological dose of molecular iodine of 3 to 60 mg per day. The solid oral dosage form is designed to have a low risk of thyroid related adverse clinical events for patients with deficiencies of certain minerals. The solid oral dosage form includes a source of iodine, a reactive agent, and calcium or iron. The solid oral dosage form may include one or more of selenium, vitamin A, vitamin D, zinc, gamma-linolenic acid, vitamin B1, and magnesium. The solid dosage form may further comprise an enteric coating that coats ingredients that are absorbed predominantly from the intestines, such as vitamin A and D, and does not coat the source of iodine and the reactive agent.
    Type: Application
    Filed: November 22, 2014
    Publication date: May 28, 2015
    Applicant: BioPharmX, Inc
    Inventors: Jack Kessler, Robert Kehl Sink
  • Publication number: 20140154297
    Abstract: Substrates having antimicrobial films or coatings adhered to a surface of the substrate and methods for replenishing the antimicrobial activity of films or coatings adhered to substrate surfaces are disclosed. The antimicrobial films and coatings comprise a strongly basic anion-exchange resin and an anion bound to the strongly basic anion-exchange resin, the anion being free of transition metals. The methods involve exposing a film or coating to an anion having antimicrobial activity, the anion being free of transition metals, and the film or coating comprising a strongly basic anion-exchange resin, thereby obtaining an antimicrobial film or coating comprising the anion bound to the strongly basic anion-exchange resin.
    Type: Application
    Filed: October 30, 2012
    Publication date: June 5, 2014
    Applicants: Baxter Healthcare S.A., Baxter International Inc.
    Inventors: Baxter International Inc., Baxter Healthcare S.A.
  • Patent number: 8642057
    Abstract: Antimicrobial solutions and delivery systems for them use liquid antimicrobial solutions with: at least 80% of total weight of a carrier liquid comprising water, alcohol or a mixture of water and alcohol; at least 0.0001% by weight of the solution of I2; at least 0.0001% by weight of CuSO4; and sufficient acid in the solution top provide a pH of less than 7.0. A buffering system is also preferable in the solution, and the solution may be provided directly as a liquid, as a spray, as a gel, imbibed and carried in a wipe, encapsulated solution, segregated droplets of solution (in carrying layers of particles, dispersed in a solid of gel carrier) and the like.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: February 4, 2014
    Assignee: Biolargo Life Technologies, Inc.
    Inventors: Kenneth R. Code, Joseph L. Provenzano, Richard D. Bickerstaff
  • Publication number: 20130323290
    Abstract: Antitoxic fibers and fibrous media contain impregnated material including an antitoxin. A method for producing antitoxic fibers and fibrous media includes impregnating a fibrous media by dipping in a dipping solution containing a concentrate of an antitoxin to form a fiber with impregnated material including an antitoxin. The impregnated material is at least about 1.0% to about 2.5% by weight of the fibers and includes additive chemical components including at least one of an anionic, cationic or nonionic component, an oil and/or an organic solvent, and an alcohol. The additives include those found in a spin finish. The antitoxin is in an amount of at least 0.1% by weight of the fiber. The manufacturing process can be applied to any woven or nonwoven media.
    Type: Application
    Filed: June 3, 2013
    Publication date: December 5, 2013
    Inventors: Pierre Jean Messier, David Ohayon
  • Patent number: 8574610
    Abstract: An article or material is applied to the environment of the body of an animal (including humans) to provide both absorbency and antimicrobial activity. The article or material may comprise a water absorbent material; and a composition that reacts with water to produce molecular iodine. The composition provides a local concentration (in the water) of at least 10 parts per million iodine in water carried by the material (that is actual water supported by the water absorbent material) when the material has 5% by weight of water present in the water absorbent. The material may be a flowable material, or the article may be diaper, sanitary pad, bandage, adhesive pad or wrap for an animal.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: November 5, 2013
    Assignee: Biolargo Life Technologies, Inc.
    Inventor: Kenneth R. Code
  • Publication number: 20130149367
    Abstract: The invention provides a novel method for producing an antitoxic nonwoven fabric by molecularly grafting the antitoxic molecule thereto. The method comprises immersing a fibrous media comprising a material having a melt flow index of less than 150 MFI in a stable antitoxin solution comprising an antitoxin, preferably triiodide. The wet media is processed through rollers, thereby forcing the antitoxic molecule (e.g., iodine) to penetrate the media. The wet media is dried, and the fabric isolated therefrom. The invention further provides products incorporating the antitoxic media formed by this molecularly grafting method, including a wound dressing, surgical drape, privacy curtain, facemask, gown, article of protective clothing, shoe covering, hair covering, air filter, medical tape, and wipe.
    Type: Application
    Filed: December 10, 2012
    Publication date: June 13, 2013
    Applicant: TRIOMED INNOVATIONS CORP.
    Inventor: TrioMed Innovations Corp.
  • Patent number: 8303994
    Abstract: A method for killing or substantially eradicating a pathogen in the upper respiratory tract of a mammal is disclosed. The method comprises generating molecular iodine (I2) in situ using an oxidant-reductant reaction with a minimum concentration of at least about 25 ppm of I2 and I2 comprises at least 40% of the total iodine atoms. A method for inhibiting superantigens using molecular iodine is also disclosed.
    Type: Grant
    Filed: June 22, 2006
    Date of Patent: November 6, 2012
    Inventors: Jack Howard Kessler, James Carlton Richards
  • Patent number: 8257749
    Abstract: A process reduces the insect, arthropod or pest content in land mass by providing molecular iodine in the land mass in a concentration in aqueous material in the land mass of at least 10 parts per million. The molecular iodine may be added in gaseous or liquid or solid state, and may be formed in situ in the land mass using available water in the reaction.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: September 4, 2012
    Assignee: Biolargo Life Technologies, Incorporated
    Inventor: Kenneth R. Code
  • Patent number: 8206752
    Abstract: A method for rejuvenating a reverse osmosis (RO) membrane which is subject to biofilm and other contaminants in an aqueous system through the use of a free molecular iodine solution at a pH of about 2.2 to 4.0.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: June 26, 2012
    Assignee: Biomedical Development Corporation
    Inventors: Gregg Siegel, Phyllis Siegel
  • Patent number: 8178120
    Abstract: Methods for processing substrate surfaces carrying coatings comprising a metal are disclosed. The methods involve providing a substrate surface having a coating comprising a metal, and exposing the substrate surface to a mixture including an oxidizing agent and an anion.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: May 15, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Nathan A. Vandesteeg, John-Bruce D. Green, Vadim V. Krongauz, Phillip W. Carter, Dustin C. Cawthon
  • Patent number: 7976876
    Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) a mixture of a coenzyme having reducing ability and a quinone, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: July 12, 2011
    Assignee: Well-Being Biochemical Corp.
    Inventors: Jih-ru Hwu, Shwu-chen Tsay
  • Patent number: 7915312
    Abstract: The present invention is directed to a physiological method for improving vision in a human patient. This method involves topical application to the eye, an amount of acetylcholine esterase inhibitor containing composition so that it is sufficient to provide a therapeutic benefit to improve the visual acuity in the human patient. The composition is administered topically and at bedtime after an eye straining work for about 20 minutes. The method disclosed herein is used for treatment and prevention of congenital and acquired color vision blindness, treatment of ocular hypertension and glaucoma, prevention of the progression of myopia, treatment of strabismus or squint, potentiation of best visual acuity, neuro-protection, treatment of aberrations secondary to pupil dilation.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: March 29, 2011
    Inventor: Gerard M. Nolan
  • Patent number: 7897779
    Abstract: The present invention relates to novel 1,4-dihydropyridine derivatives, to novel cosmetic or dermatological sunscreen compositions containing these derivatives and the use of these derivatives for photoprotecting human skin and/or hair against UV radiation, in particular solar radiation.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: March 1, 2011
    Assignee: DSM IP Assets B.V.
    Inventors: Katja Berg-Schultz, Ulrich Huber, Daniel Sprenger
  • Publication number: 20100135914
    Abstract: A fumigant composition including an azeotropic mixture of methyl iodide and sulfuryl fluoride; and a method of controlling at least one target insect species including treating a target space with a composition including an azeotropic mixture of methyl iodide and sulfuryl fluoride by applying an amount of the composition to the target space that is effective to kill a substantial portion of the target insect species in multiple development stages.
    Type: Application
    Filed: December 3, 2008
    Publication date: June 3, 2010
    Inventors: Andrew Joseph Poss, Rajiv Ratna Singh, Hang T. Pham
  • Publication number: 20090191258
    Abstract: Compositions provided according to embodiments of the present invention include an inorganic clay admixed with an iodine-containing substance. Suitable iodine-containing substances include I2 and/or one or more iodine salts. Methods of treating a condition or disorder are provided according to the present invention which include administration of a therapeutically effective amount of a composition including an inorganic clay admixed with an iodine-containing substance to an affected subject. Optionally, the composition is administered in an article of manufacture to the affected area.
    Type: Application
    Filed: January 26, 2009
    Publication date: July 30, 2009
    Inventor: Roy J. Mankovitz
  • Publication number: 20080299103
    Abstract: Well-preserved aqueous topical compositions that satisfy one or more widely recognized organic certification standards. The compositions comprise a preservative system comprising an in situ hypoiodite generator; and a plant extract blend; optionally, an essential oil blend. Such compositions do not require synthetic preservatives, especially parabens. Suitable aqueous compositions may contain an oil phase, such as oil-in-water or water-in-oil emulsions.
    Type: Application
    Filed: June 1, 2007
    Publication date: December 4, 2008
    Inventors: Liliana George, Steve Schnittger, Kathy Kretzschmar, Charles Craig Tadlock, Monica Apostol
  • Publication number: 20080145390
    Abstract: Method and article for providing a rapid, broad spectrum bacterial control, and a rapid and persistent antiviral control on an inanimate surface is disclosed. In the method, a compound or composition capable of lowering surface pH to less than about 4 is applied to the surface, and preferably is allowed to remain on the surface, and the nonvolatile components of the composition can form a barrier film or layer on a treated surface.
    Type: Application
    Filed: June 4, 2007
    Publication date: June 19, 2008
    Applicant: THE DIAL CORPORATION
    Inventors: Timothy J. Taylor, Harry E. Towner, Janice L. Fuls, Bruce R. Cox, George E. Fischler, Priscilla S. Fox, Nancy D. Rodgers, James Dalton, Daniel E. Pedersen, John J. Rolando, Richard K. Staub
  • Patent number: 7387799
    Abstract: The present invention relates to an anti-bacterial, anti-viral, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: June 17, 2008
    Assignee: Well-Being Biochemical Corp.
    Inventors: Jih-Ru Hwu, Shwu-Chen Tsay
  • Publication number: 20080008769
    Abstract: The invention provides a method for treating urinary tract infections in a patient by providing a mouth rinsing composition which releases free molecular iodine into the mucous membranes which enters into the urinary tract.
    Type: Application
    Filed: July 5, 2006
    Publication date: January 10, 2008
    Inventors: Gregg Siegel, Phyllis Siegel
  • Publication number: 20070286907
    Abstract: A method and composition for removing biofilm, disinfecting and inactivating endotoxin which generates a safe level of molecular iodine that is free of persulfate ions. The composition can be used in households, industry, on medical equipment and skin surfaces.
    Type: Application
    Filed: December 29, 2005
    Publication date: December 13, 2007
    Inventors: Gregg Siegel, Phyllis Siegel
  • Patent number: 7285292
    Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium and which comprises a concentration of the metal(s) of at least 60 mg/ml. The solution further comprises at least one compound selected from the group comprising iodine, potassium iodide, sodium iodide, iron, iron chloride, zinc oxide, manganese sulphate, sodium selenite, copper carbonate, sodium carbonate, anhydrous disodium EDTA and sodium hydroxide. The trace element solution is prepared by a method consisting essentially of the steps of preparing a MnCO3 mixture in a container; adding an EDTA/NaOH mixture to the container and subsequently adding at least one metal compound; and adding Na2SeO3 to the container to obtain the trace element solution. The method also comprises the step of adding CrCl3.6H2O to the trace element solution.
    Type: Grant
    Filed: April 29, 2004
    Date of Patent: October 23, 2007
    Assignee: Warburton Technology Limited
    Inventors: Robert Naylor Laurie, William Alfred Smith
  • Patent number: 7153527
    Abstract: A teat dip composition comprising from about 0.1% to about 2% iodine by weight of the composition on a formulation basis and form about 45% to about 99.9% propylene glycol by weight of the composition on a formulation basis, and a method of using such composition to treat mastitis.
    Type: Grant
    Filed: June 7, 2005
    Date of Patent: December 26, 2006
    Assignee: WestfaliaSurge, Inc.
    Inventors: Charles D. Gradle, Alejandro O. Dee
  • Patent number: 7014871
    Abstract: An iodine preparation composition suitable for use on wounds comprising an iodide source, an oxidant and a buffer characterized in that the iodide is held separately from the oxidant until the point of use, and that the buffer is capable of maintaining the pH of the composition at between pH 45 and pH 6 so that iodine is generated at a physiologically acceptable dose rate.
    Type: Grant
    Filed: March 13, 2000
    Date of Patent: March 21, 2006
    Inventors: Dave Parsons, Elizabeth Jacques, Philip Bowler
  • Patent number: 6962714
    Abstract: The present invention relates to antimicrobial compositions including a critical, near critical, or supercritical (densified) fluid and an antimicrobial agent, to methods of forming these compositions, and to methods employing these compositions. An antimicrobial agent can be generated in the presence of a densified fluid, for example, by reacting an oxidizing agent with a precursor to the antimicrobial agent.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: November 8, 2005
    Assignee: Ecolab, Inc.
    Inventors: Robert D. P. Hei, Keith E. Olson, Robert J. Ryther, Richard K. Staub
  • Patent number: 6939569
    Abstract: There is disclosed a medical device for implantation that acts to prevent transmission of infectious agents. Specifically, the present invention provides implantable devices, such as catheters or living skin matrices or wound dressings, for insertion into various body cavities or over wound sites to confer to the site microbicidal or virucidal activity. Devices in the disclosure designed as vaginal inserts also exhibit contraceptive spermicidal activity. The coated devices or devices having the inventive polymeric material interspersed throughout are formed into appropriate shapes according to their contemplated uses (such as catheters or Foley catheters). Further, the present invention provides devices for providing therapeutic anti-microbial activity into an infected body cavity or on an infected wound site.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: September 6, 2005
    Assignee: Oxibio, Inc.
    Inventors: Terrence R. Green, Jack Fellman
  • Patent number: 6926913
    Abstract: The invention provides a composition of matter comprising molecular iodine and tetraglycol.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: August 9, 2005
    Assignees: Ben Gurion University of the Negev Research & Development Authority, Yissum Research Development Company of the Hebrew
    Inventors: Uri Wormser, Amnon Sintov
  • Patent number: 6908628
    Abstract: Wide spectrum disinfecting and antiseptic composition for use in the fields of human medicine, veterinary science and industry, characterized because it includes: Hydrogen peroxide, lactic acid and halogen salts (Br, I) and/or salts of heavy metals (for example, silver halides) with surfactant agents, either cationic, like chlorhexidine and/or quaternary ammonium salts, like didecyl-methyl-polyoxy-ethyl-ammonium propionate, chlorides of ammonium or compounds of ammonium propylamide or anionic, like lauryl sulphate, dodecyl sulphate or alkyl succinic salts, with suitable excipients, some of which may be ethyl or isopropyl alcohol, chlorhexidine, non-chlorinated quaternary ammonium salts, like didecyl-methyl-polyoxy-ethyl-ammonium propionate, combined or not with iodine, and/or its salts, together with excipients, some of which may be ethyl or isopropyl alcohol.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: June 21, 2005
    Assignee: OFTRAI, S.L.
    Inventor: Rafael Herruzo Cabrera
  • Patent number: 6902747
    Abstract: A teat dip composition comprising from about 0.1% to about 2% iodine by weight of the composition on a formulation basis and from about 50% to about 99.9% propylene glycol by weight of the composition on a formulation basis, and a method of using such composition to treat mastitis.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: June 7, 2005
    Assignee: WestfaliaSurge, Inc.
    Inventors: Charles D. Gradle, Alejandro O. Dee
  • Patent number: 6866869
    Abstract: A liquid antimicrobial composition comprises: (1) a mixture of iodide anions and thiocyanate anions; (2) periodic acid or an alkali metal salt thereof; and (3) optionally, a peroxidase. The composition may be used as a microbicide, disinfectant or for suppressing or killing viruses or spores.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: March 15, 2005
    Assignee: BASF Aktiengesellschaft
    Inventors: Walter Graham Guthrie, Mohammed Shoaib Qureshi, Lawrence Alan Staniforth, Darren Michael Hodgkinson, David Wilson Ashworth
  • Patent number: 6855328
    Abstract: An improved antimicrobial composition is described as a liquid concentrate. The liquid concentrate includes a complex resulting from an in-situ reaction of a cation source, an oxidant, a halide source having at least one iodine atom, and a non-mineral acid, or a mixture of a non-mineral acid to about 50% of a hydrophilic solvent by volume.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: February 15, 2005
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, Francis L. Richter, Duane Joseph Reinhardt, Brian R. Leafblad
  • Patent number: 6852340
    Abstract: A biodegradable composition having long term phase and composition stability, and a method for producing both short and long period biocide activity, is used for disinfecting animal husbandry surfaces, in the medical and food industry, and the like. The composition contains propionic acid for pH control, and preferably iodine or an iodine containing compound. The propionic acid combines with ambient ammonia, or ammonia containing compounds arising from fermenting litter and manure to form ammonium propionate, which in turn inhibits or prevents microorganism formation, including mold formation. A surfactant which complexes with the iodine may also be used for spraying onto surfaces, and is effective in the presence of a high organic challenge and hard water.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: February 8, 2005
    Assignee: Preserve International
    Inventors: Gary E. Gaumer, Bruce A. Spielholz
  • Patent number: 6830764
    Abstract: Application of an alkaline earth metal salt selected from calcium and strontium salts can steadily denature the allergens those exist in the environment without any coloring trouble on the treated material.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: December 14, 2004
    Assignees: Shinto Fine Co., Ltd., Sumitomo Chemical Co., Ltd.
    Inventors: Keiichiro Inui, Mariko Mikame
  • Patent number: 6814984
    Abstract: The present invention is directed to frozen biocidal compositions. Specifically, the biocidal compositions comprise a frozen aqueous solution of a plurality of ions selected from the group consisting of halide and oxyhalide ions. The frozen biocidal compositions are useful in preserving or extending the shelf-life of perishable articles.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: November 9, 2004
    Assignee: Clean Water International LLC
    Inventors: David C. Rose, Lawrence J. Ventura
  • Patent number: 6777003
    Abstract: An iodine complex concentrate containing (a) from about 0.5 to about 30% by weight of iodine; (b) from about 0.2 to about 14% by weight of an iodide component selected from the group consisting of iodide salt, iodide acid and mixtures thereof; and (c) from about 2% to about 85% by weight of a nonionic sugar surfactant selected from the group consisting of alkyl glucose esters, aldobionamides, gluconamides, glyceramides, glyceroglycolipids, polygydroxy fatty acid amides, alkyl polyglycosides having the general formula I: R1O(R2O)b(Z)a  I wherein R1 is a monovalent organic radical having from about 6 to about 30 carbon atoms; R2 is divalent alkylene radical having from 2 to 4 carbon atoms; Z is a saccharide residue having 5 or 6 carbon atoms; b is a number having a value from 0 to about 12; a is a number having a value from 1 to about 6, and mixtures thereof, all weights being based on the weight of the concentrate.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 17, 2004
    Assignee: Cognis Corporation
    Inventors: Suresh Desai, John Frederick Hessel
  • Patent number: 6696041
    Abstract: The invention relates generally to a method which utilizes iodine as a broad spectrum microbicide wherein the active agent may be applied in nasal passages in the manner of a decongestant type nose spray. The spray is intended particularly for human use. It is to be applied in the event of known or suspected exposure of the individual to common cold virus, flu, or other infective microbial agents including for example, bacteria, viruses, rickettsia, and even mold and fungus. The active agent is based on an iodine solution and may also contain one or more of the following: sodium hypochlorite solution, or a solution of chlorine or hypochlorites plus a salt of chloride, bromide or iodide. Alternatively, the solution may further contain iodine and a bromine solution, or a solution of iodine, bromine plus a salt of chloride, bromide or iodide such as sodium chloride, zinc chloride, sodium bromide, zinc bromide, sodium iodide or zinc iodide.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: February 24, 2004
    Inventor: Richard L. Hansen
  • Patent number: 6696055
    Abstract: The present invention relates to a method for treating air with an iodinated resin to remove contaminants contained in the air. The iodinated resin is an iodinated anion exchange resin. The present invention also relates a system for treating air. The system comprises a means for providing an air path for air to move through, and an iodinated resin disposed in the air path.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: February 24, 2004
    Assignee: Triosyn Holdings, Inc.
    Inventor: Pierre Jean Messier
  • Patent number: 6663902
    Abstract: The present invention relates to a biocidal composition, designed for the generation of chlorine dioxide, comprising at least one iodo-compound having at least one iodine atom and a source of chlorite ions. The molar ration of chlorite ions to iodine atoms is 2 or greater. The composition finds use in a variety of applications including methods of cleaning, sanitizing, deodorizing, and disinfecting various surfaces.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: December 16, 2003
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, David Daniel McSherry, Kim R. Smith, Keith E. Olson
  • Publication number: 20030198692
    Abstract: The present invention provides an antimicrobial composition. The composition comprises a cell-permeabilising agent and at least one compound of general formula (I) wherein R1 and R2 are independently H, halogen, alkyl, alkoxy, oxoalkyl, alkenyl, aryl or arylalkyl whether unsubstituted or substituted, optionally interrupted by one or more heteroatoms, straight chain or branched chain, hydrophilic fluorophilic; R3 and R4 are independently H, halogen, alkyl, aryl or arylalkyl, alkoxy; R3 or R4+R2 can be saturated or an unsaturated cycloalkane; and “” represents a single bond or a double bond provided that at least one of R1, R2, R3 and R4 is a halogen.
    Type: Application
    Filed: October 28, 2002
    Publication date: October 23, 2003
    Inventors: Gerd Pia Carola Holmstrom, Staffan Kjellberg
  • Publication number: 20030175359
    Abstract: The object of the present invention is to allow an egg originally having almost no active oxygen eliminating ability, to strongly possess an active oxygen eliminating ability. It was found that an egg containing a high level of iodine (4.2 ppm or more) has an ability to eliminate active oxygen, which acts harmfully on the human body.
    Type: Application
    Filed: March 12, 2002
    Publication date: September 18, 2003
    Inventors: Kunitoshi Sekimoto, Akiko Matsuki, Ayuko Kashimori
  • Patent number: 6605640
    Abstract: The present invention is directed to methods for treating diminished visual acuity in a human patient who has been diagnosed as suffering from a disease or disorder of the posterior region of the eye. These involve topical application to the eye, an amount of acetylcholine esterase inhibitor containing composition is carried out so that it is sufficient to provide a therapeutic benefit to alleviate the diminished visual acuity in the human patient. The composition is administered at bedtime after an eye straining work for about 20 minutes.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: August 12, 2003
    Inventor: Gerard M. Nolan
  • Patent number: 6592890
    Abstract: A wound dressing having anti-infective activity. The wound dressing provides stable and improved formulations of precursors required in generating anti-infective iodine specifically within a wound site where the oxygen tension may be very low. Furthermore, the design of the invention precludes interference by catalase (and other heme proteins.) in competing for hydrogen peroxide where hydrogen peroxide is used as a component of the iodine generating formulation, ensuring more efficient and sustained production of free iodine as a potent anti-infective agent. The invention takes advantage of the physical design of the wound dressing, and the permeation of body fluid into the dressing, which together serve to initiate formation of nascent iodine concomitant with placement of the dressing into, or over, a wound site.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: July 15, 2003
    Assignee: OxiBio, Inc.
    Inventor: Terrence R. Green
  • Publication number: 20030108621
    Abstract: A method of increasing vaginal lubrication in an adult human female by orally administering to the female an effective amount of an aqueous solution having a pharmaceutically acceptable water-soluble iodide salt.
    Type: Application
    Filed: June 12, 2002
    Publication date: June 12, 2003
    Applicant: RAINBURST, LLC
    Inventor: Susann Reilly
  • Patent number: 6565891
    Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among children.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: May 20, 2003
    Assignee: Tsar Health Private Ltd.
    Inventor: Ranjit Kumar Chandra
  • Patent number: 6562378
    Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among adolescents.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: May 13, 2003
    Assignee: TSAR Health Private Ltd.
    Inventor: Renjit Kumar Chandra
  • Patent number: 6534075
    Abstract: An antimicrobial and antiviral composition in powder form or in the form of a two part liquid concentrate for washing and sanitizing foods, food surfaces, food ware, process waters, animal quarters, and animal carcasses is described. The composition may also be used to reduce the microbial and viral population on animals; reducing human pathogenic microbes, reducing opportunistic pathogenic microbes on eggs, and treating skin diseases. The composition includes three reactive species which in solution form an oxidizing species, and optionally a food grade acid source. The reactive species include a natural source of a quaternary or protonizable nitrogen compound which is acceptable on foods, an oxidant and a halide source.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: March 18, 2003
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, Kim R. Smith, Polly D. Laugen, Bruce R. Cords, Shaun P. Kennedy
  • Patent number: 6521243
    Abstract: This invention describes non-staining, pharmaceutically useful compositions of ionic complexes made between the cationic polymer chitosan or its derivatives and the small anionic iodine-iodide complex (ICIC's). Unlike previously disclosed ion transfer chitosan iodine complexes, ICIC's were found to possess dramatically higher viscosity than those of each ingredient separately, and instantly form a gel structure that is easily dispersible upon shaking. In addition to their antiseptic power, ICIC's showed better skin biocompatibility than povidone iodine and effectively promoted wound healing.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: February 18, 2003
    Assignee: Pharma C and D, Limited
    Inventor: EmadEldin M. Hassan
  • Patent number: 6506737
    Abstract: An oxidizing species is described herein as a reaction product through an in situ preparation combining a protonizable phosphorus or sulfur compound, and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or powdered media. The oxidizing species can be used to reduce microbial and viral populations on a surface or object or in a body or stream of water. The invention thus finds applications as a bleach, sanitizer, oxidant, or in any other application in which an oxidizing agent can be beneficially used alone or in a formulation.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: January 14, 2003
    Assignee: Ecolab, Inc.
    Inventors: Robert D. P. Hei, Kim Smith
  • Patent number: 6447811
    Abstract: A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic microorganisms such as fungi and bacteria. Preferably the formulation also contains an oil.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: September 10, 2002
    Assignees: Koppert B.V., Campina-Melkunie B.V.
    Inventors: Willem Jacobus Ravensberg, Richard Karel Van der Pas, Klaas Daniel Kussendrager, Johannes Antonius Maria Maas
  • Patent number: 6436445
    Abstract: An oxidizing species is described herein as a reaction product through an in situ preparation combining a quaternary or protonizable nitrogen compound, an oxidant compound and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or powdered media. The oxidizing species can be used to reduce microbial and viral populations on a surface or object or in a body or stream of water. The invention thus finds applications as a bleach, sanitizer, oxidant, or in any other application in which an oxidizing agent can be beneficially used alone or in a formulation.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: August 20, 2002
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, Kim R. Smith, Polly D. Laugen, Shaun P. Kennedy
  • Patent number: 6410060
    Abstract: This invention relates to the method of non-invasively fortifying eggs with iodine as a dietary supplement without compromising the structural integrity of the egg. The eggs are placed in a solution comprising iodide or iodate salts of alkali or alkali earth metals at an effective concentration for a duration of between a few seconds to a few days. Iodine then passes through the egg shell to the interior of the egg until an adequate internal iodine concentration of iodide or iodate salts is produced.
    Type: Grant
    Filed: May 19, 1998
    Date of Patent: June 25, 2002
    Assignee: Biophile Corporation
    Inventors: Pichit Suvanprakorn, Lerson Tanasugarn, Anusig Limahksohn, Sangsom Sinawat, Prakrom Vuthipongse