Iodide Patents (Class 424/669)
-
Patent number: 6410060Abstract: This invention relates to the method of non-invasively fortifying eggs with iodine as a dietary supplement without compromising the structural integrity of the egg. The eggs are placed in a solution comprising iodide or iodate salts of alkali or alkali earth metals at an effective concentration for a duration of between a few seconds to a few days. Iodine then passes through the egg shell to the interior of the egg until an adequate internal iodine concentration of iodide or iodate salts is produced.Type: GrantFiled: May 19, 1998Date of Patent: June 25, 2002Assignee: Biophile CorporationInventors: Pichit Suvanprakorn, Lerson Tanasugarn, Anusig Limahksohn, Sangsom Sinawat, Prakrom Vuthipongse
-
Publication number: 20020058072Abstract: A method of increasing vaginal lubrication in an adult human female by orally administering to the female an effective amount of an acidic solution having a pharmaceutically acceptable water-soluble iodide salt, wherein hydriodic acid is generated in situ.Type: ApplicationFiled: October 26, 2001Publication date: May 16, 2002Inventor: Susann Reilly
-
Patent number: 6361800Abstract: This invention is directed to a multi-vitamin and mineral supplement which supplies the right amount of the right micronutrients at the right time to assure adequate intake of micronutrients needed for disease prevention and protection against nutritional losses and deficiencies due to lifestyle factors and common inadequate dietary patterns. The multi-vitamin and mineral supplement is comprised of vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, niacinamide, vitamin B6, vitamin B12, biotin, pantothenic acid, iron, phosphorus, iodine, magnesium, zinc, selenium, copper, chromium, potassium, choline, lycopene, and co-enzyme Q-10.Type: GrantFiled: April 13, 2000Date of Patent: March 26, 2002Assignee: Cooper Concepts, Inc.Inventors: Kenneth H. Cooper, Ishwarlal Jialal, Scott Montgomery Grundy, Walter Churchill Willett, Jacob Selhub
-
Publication number: 20010036482Abstract: Antimicrobial compositions containing an iodine compound and a carboxylic acid, for example, a fatty acid, are disclosed. The compositions can be formulated for use as a surgical scrub, wound antiseptic, pre-operative skin preparation, industrial sanitizer, antimicrobial soap, teat dip, etc. In one particularly advantageous embodiment, a composition of the invention is formulated as a teat dip further including a rheology modifier, at least one surfactant, suitable emollients, skin conditioners and lubricants.Type: ApplicationFiled: October 15, 1999Publication date: November 1, 2001Inventors: DALE LIND FREDELL, FRANCIS LAWRENCE RICHTER, BENJAMIN R. BODE
-
Patent number: 6248335Abstract: A stabilized solid oral pharmaceutical composition comprised of iodide and iodate as the active agents in the presence of one or more pharmaceutical excipients and a method for preparing these stabilized compositions.Type: GrantFiled: February 26, 1999Date of Patent: June 19, 2001Assignee: Symbollon CorporationInventors: Yongjun Duan, Kirk Dinehart, John Hickey, Jack Kessler
-
Patent number: 6165485Abstract: A bentonite based organoclay, when mixed with a biocidal quaternary amine containing a benzyl molecule within its structure, acts as a reasonably effective biocide.When this organoclay is further treated with iodine and iodide compounds, its efficiency is greatly enhanced.Type: GrantFiled: July 28, 1998Date of Patent: December 26, 2000Assignee: Biomin, Inc.Inventor: George Alther
-
Patent number: 6153229Abstract: Stable aqueous glycerin iodine concentrates are provided which are adapted for dilution in water to yield germicidal iodine use solutions. The concentrates include from about glycerin, iodine, and iodide ion. Preferably, the concentrates further include one or more additives such as compatible wetting agents, hydrotropes, thickening agents, additional emollients and buffering systems. The quantities of iodide ion and iodine are such that the ratio of iodide ion to iodine is from about 0.5:1 to about 6:1. The concentrates are stable for a period of at least about 3 months at room temperature and are dilutable at a ratio of 1 part concentrate with from about 2-80 parts water. The concentrates can be formulated to give very low free iodine values as concentrates which dramatically increase in diluted use solutions to values which are from about 2 to about 300 times greater than the free iodine in the concentrates.Type: GrantFiled: September 30, 1998Date of Patent: November 28, 2000Assignee: West Agro, Inc.Inventor: Chris Foret
-
Patent number: 5980827Abstract: The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong base anion exchange resin in a salt form, is contacted with a material capable of donating a member absorbable by the resin so as to convert the resin to the polyiodide-resin. The adsorbable member is selected from the group comprising I.sub.2 and polyiodide ion having a valence of -1. The process is characterized in that conversion of the anion exchange resin to the polyiodide-resin is effected at elevated temperature and elevated pressure, the elevated temperature being 100 degrees C. or higher, the elevated pressure being greater than atmospheric pressure. The present invention also relates to disinfectant substance comprising an iodine (impregnated) resin as produced by the above process.Type: GrantFiled: February 24, 1997Date of Patent: November 9, 1999Inventor: Pierre Jean Messier
-
Patent number: 5962029Abstract: A method for forming an iodine disinfecting solution that continuously generates free molecular iodine at a controlled average rate of at least 0.2 ppm per hour over a sustained and extended time period. The method involves combining persulfate anions and iodide anions in sufficient quantity in an aqueous medium having a resulting pH of less than about 6.5 so as to create an iodine generating capacity in said aqueous medium of between 1.5 and 6.5 with a generated concentration of at least 5 ppm of free molecular iodine and maintaining this concentration over the course of the extended time period.Type: GrantFiled: July 5, 1996Date of Patent: October 5, 1999Assignee: Symbollon CorporationInventors: Yongjun Duan, Jack Howard Kessler
-
Patent number: 5955101Abstract: The present invention is concerned with the use of starch containing amylose as a complexant with iodine for preparing dry powder pharmaceutical formulations useful in the preparation of capsules or tablets. The helical structure of the amylose molecule and its ability to complex. with smaller molecules including iodine make starch (amylose) a desirable vehicle for the administration of iodine (I.sub.2) as a dry powder formulation in capsule or tablet form. These pharmaceutical formulations are particularly useful in the treatment of or the prevention of iodine deficiency diseases including breast dysplasia, breast cancer, endometriosis, premenstrual syndrome and radiation sickness from nuclear fallout.Type: GrantFiled: November 5, 1996Date of Patent: September 21, 1999Assignee: 943038 Ontario Inc.Inventors: William R. Ghent, deceased, Bernard A. Eskin
-
Patent number: 5916581Abstract: Stable, aqueous, iodine-based germicidal compositions are provided which include respective amounts of available iodine, non-ionic surfactant (e.g., polyoxyethylene, polyoxypropylene block copolymers) and an iodine-solubilizing halide ion selected from the group consisting of Cl.sup.- and Br.sup.- and mixtures thereof. Use of Cl.sup.- and/or B.sup.- substantially reduces or completely eliminates the need for iodide ion in the compositions for maintaining available iodine in solution. The compositions can be in the form of dilutable concentrates or final use solutions.Type: GrantFiled: October 21, 1997Date of Patent: June 29, 1999Assignee: West Agro, Inc.Inventors: Chris Foret, Thomas C. Hemling
-
Patent number: 5910318Abstract: The present invention is concerned with the use of starch containing amylose as a complexant with iodine for preparing dry powder pharmaceutical formulations useful in the preparation of capsules or tablets. The helical structure of the amylose molecule and its ability to complex with smaller molecules including iodine make starch (amylose) a desirable vehicle for the administration of iodine (I.sub.2) as a dry powder formulation in capsule or tablet form. These pharmaceutical formulations are particularly useful in the treatment of or the prevention of iodine deficiency diseases including breast dysplasia, breast cancer, endometriosis, premenstrual syndrome, ovarian cysts and radiation sickness from nuclear fallout.Type: GrantFiled: January 29, 1996Date of Patent: June 8, 1999Assignee: 943038 Ontario Inc.Inventors: William R. Ghent, deceased, Bernard A. Eskin
-
Patent number: 5885620Abstract: Stable aqueous glycerin iodine concentrates are provided which are adapted for dilution in water to yield germicidal iodine use solutions. The concentrates include from about 30-87% by weight glycerin, from about 0.15-15% by weight iodine, from about 0.15-15% by weight iodide ion, and one or more additives such as compatible wetting agents, hydrotropes, thickening agents, additional emollients and buffering systems. The concentrates are stable for a period of at least about 3 months at room temperature and are dilutable at a ratio of 1 part concentrate with from about 2-80 parts water. The concentrates can be formulated to give very low free iodine values as concentrates, but provide dramatically increased free iodine values as diluted use solutions.Type: GrantFiled: April 2, 1997Date of Patent: March 23, 1999Assignee: West Agro, Inc.Inventor: Chris Foret
-
Patent number: 5879717Abstract: A wound-healing preparation comprises a solution or paste of a non-reducing sugar and iodine in a vehicle consisting essentially of a pharamcologically acceptable glycol, especially glycerol, and, optionally, water. Preferably, the sugar is sucrose, especially that obtained from sugar beet, and the vehicle is substantially anhydrous glycerol. In one preferred embodiment, the preparation is in the form of a veterinary infusible solution and is particularly useful in the treatment of mastitis. In another embodiment, surgical sutures are treated by coating with the preparation to prevent the presence or abscesses around surgical suture lines.Type: GrantFiled: May 28, 1997Date of Patent: March 9, 1999Assignee: Rita McConn-SternInventors: Rita McConn-Stern, Thomas C. Walsh
-
Patent number: 5817344Abstract: Non-aqueous emollient iodophor formulations for use as a skin washing agents, comprising non-ionic surfactants, coconut oil, mineral oil, iodine, sodium iodide and an organic base solvent. The non-aqueous formulations substantially do not irritate the skin and will provide antimicrobial effectiveness to the skin.Type: GrantFiled: September 17, 1997Date of Patent: October 6, 1998Assignee: Becton, Dickinson and CompanyInventors: Minh Quang Hoang, Mohammad Ali Khan
-
Patent number: 5776479Abstract: Improved, stable, germicidal, aqueous teat-dip compositions are disclosed, which include a film-forming agent selected from the group consisting of hydroxyethylcellulose, methyl hydroxypropylcellulose, and ethylhydroxyethylcellulose, a germicidal agent, preferably iodine complexed with a nonionic surfactant, and water to provide a solution having a viscosity of about 50 to 1000 cp. The liquid, aqueous compositions, when applied to the teats of agricultural animals, dry to form a continuous barrier film, which functions both as an effective anti-microbial agent and as an effective barrier at the mouth of the milk channel to prevent or reduce the incidence of mastitis.Type: GrantFiled: December 20, 1996Date of Patent: July 7, 1998Assignees: The United States of America as represented by the Secretary of Agriculture, West Agro, Inc.Inventors: Ferenc M. Pallos, Thomas C. Hemling, Dominic W. S. Wong, Attila E. Pavlath
-
Patent number: 5706944Abstract: Non-aqueous emollient iodophor formulations for use as a skin washing agents, comprising non-ionic surfactants, coconut oil, mineral oil, iodine, sodium iodide and an organic base solvent. The non-aqueous formulations substantially do not irritate the skin and will provide antimicrobial effectiveness to the skin.Type: GrantFiled: August 6, 1996Date of Patent: January 13, 1998Assignee: Becton Dickinson and CompanyInventors: Minh Quang Hoang, Mohammad Ali Khan
-
Patent number: 5662913Abstract: Antimicrobial metal-based compositions, which are photostable, non-staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest," wherein stabilization of this "host-guest relationship" is accomplished through the use of excess anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices, foams and adhesives to impart infection-resistance.Type: GrantFiled: July 1, 1994Date of Patent: September 2, 1997Inventor: Christopher C. Capelli
-
Patent number: 5643608Abstract: Stable aqueous iodine/iodide/iodate germicidal compositions are provided which have relatively high quantities of free iodine therein and also substantially maintain the starting amounts of available and free iodine throughout a storage period of at least about three months. The compositions of the invention contain from about 0.01-1.4% by weight available iodine, from about 10-125 ppm free iodine, from about 0.005-0.5% by weight iodate ion, from about 0.1-15% by weight of iodine complexing agent, from about 0.004-0.5% by weight iodide ion, and have a pH of from about 2.0-4.5.Type: GrantFiled: March 1, 1996Date of Patent: July 1, 1997Assignee: West Agro, Inc.Inventors: Michael D. McKinzie, Murray W. Winicov
-
Patent number: 5639452Abstract: The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong base anion exchange resin in a salt form, is contacted with a material capable of donating a member absorbable by the resin so as to convert the resin to the polyiodide-resin. The adsorbable member is selected from the group comprising I.sub.2 and polyiodide ion having a valence of -1. The process is characterized in that conversion of the anion exchange resin to the polyiodide-resin is effected at elevated temperature and elevated pressure, the elevated temperature being 100 degrees C. or higher, the elevated pressure being greater than atmospheric pressure. The present invention also relates to disinfectant substance comprising an iodine (impregnated) resin as produced by the above process.Type: GrantFiled: July 12, 1994Date of Patent: June 17, 1997Inventor: Pierre Jean Messier
-
Patent number: 5607683Abstract: Antimicrobial metal-based compositions, which are photostable, non-staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest," wherein stabilization of this "host-guest relationship" is accomplished through the use of excess anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices, foams and adhesives to impart infection-resistance.Type: GrantFiled: June 7, 1995Date of Patent: March 4, 1997Inventor: Christopher C. Capelli
-
Patent number: 5607699Abstract: Non-aqueous emollient iodophor formulations for use as a skin washing agents, comprising non-ionic surfactants, coconut oil, mineral oil, iodine, sodium iodide and an organic base solvent. The non-aqueous formulations substantially do not irritate the skin and will provide antimicrobial effectiveness to the skin.Type: GrantFiled: May 12, 1995Date of Patent: March 4, 1997Assignee: Becton Dickinson and CompanyInventors: Minh Q. Hoang, Mohammad A. Khan
-
Patent number: 5599561Abstract: A method of making poultice by mixing together water, fine mineral powder, vinegar, herbal liniment solution, and hydrated magnesium sulfate (also known as Epsom salt) to produce a poultice capable of being applied to muscles, joints, or both which may be sore, injured, or both.Type: GrantFiled: August 4, 1995Date of Patent: February 4, 1997Inventor: Angel Gonzalez, Jr.
-
Patent number: 5591397Abstract: An improved method for rapid disinfection of contact lenses in a convenient and reliable manner is disclosed in which a series of oxidation-reduction reactions are employed. Specifically, dichloroisocyanurate and potassium iodide react to form iodine species for disinfecting the contact lens. An amount of ascorbate is then added to neutralize the iodine species.Type: GrantFiled: June 7, 1995Date of Patent: January 7, 1997Assignee: Alcon Laboratories, Inc.Inventors: Ronald L. Schlitzer, N. L. Dassanayake, Rajkumar P. Bhatia
-
Patent number: 5558881Abstract: Inter alia, an iodophor preparation composition comprising, in addition to a carrier, an iodide source, an oxidant and an acid source, characterised in that at least one of the iodide source, the oxidant and the acid source is only available for reaction with the other components when dissolved in an aqueous medium at the point-of-use is disclosed.Type: GrantFiled: March 24, 1994Date of Patent: September 24, 1996Assignee: Diversey CorporationInventor: Michael P. Corby
-
Patent number: 5545401Abstract: A virucidal, spermicidal vaginal gel consisting essentially of povidone iodine having a povidone to iodine ratio of about 15:1 or higher containing from about one percent to about twenty percent low molecular weight povidone having a molecular weight of about 20 kd or lower, the gel having a viscosity such that a conical body drawn from a body of the same does not visibly slump at 37C. for a period of at least one minute and a method of preventing sexual transmission of disease and preventing pregnancy using the same are disclosed.Type: GrantFiled: June 2, 1994Date of Patent: August 13, 1996Inventor: Edward Shanbrom
-
Patent number: 5462713Abstract: An improved method for rapid disinfection of contact lenses in a convenient and reliable manner is disclosed in which a series of oxidation-reduction reactions are employed. Specifically, dicheoroisocyanurate and potassium iodide react to form iodine species for disinfecting the contact lens. An amount of ascorbate is then added to neutralize the iodine species.Type: GrantFiled: August 16, 1993Date of Patent: October 31, 1995Assignee: Alcon Laboratories, Inc.Inventors: Ronald L. Schlitzer, N. L. Dassanayake, Rajkumar P. Bhatia
-
Patent number: 5409697Abstract: A stable organic iodophor composition including an iodophor wherein the ratio or organic iodine solubilizing compound to iodine is less than 5:1 by weight, and a process for the production of an iodophor composition which process includes dissolving an organic iodine solubilizing compound and iodine or an iodine liberating substance in water in amounts such that the ratio of iodine liberating substance to iodine is less that 5:1 by weight and optionally adjusting the pH. adding an oxidizing agent and readjusting the pH following oxidation.Type: GrantFiled: February 19, 1992Date of Patent: April 25, 1995Assignee: Novapharm Research Pty. Ltd.Inventor: Bruno A. Gluck
-
Patent number: 5358722Abstract: Ferritin analogs comprising an apoferritin protein shell and a core substantially devoid of ferrihydrite, e.g. of inorganic composition such as aluminum hydroxide or organic composition such as acetaminophen. The protein shell can be removed from ferritin analog to produce spherules having a substantially monomodal nominal diameter between about 45 and 90 Angstroms.Type: GrantFiled: January 25, 1993Date of Patent: October 25, 1994Assignee: Monsanto CompanyInventor: Bruce F. Monzyk
-
Patent number: 5326567Abstract: Antimicrobial metal-based compositions, which are photostable, non-staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest," wherein stabilization of this "host-guest relationship" is accomplished through the use of excess halide anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices and adhesives to impart infection-resistance.Type: GrantFiled: June 28, 1993Date of Patent: July 5, 1994Inventor: Christopher C. Capelli
-
Patent number: 5310549Abstract: A solid iodine concentrate composition comprising an iodine complex, and a solidifier wherein said iodine complex comprises a complexing agent and an iodine source present in a ratio of at least 1.5:1.Type: GrantFiled: August 31, 1989Date of Patent: May 10, 1994Assignee: Ecolab Inc.Inventor: Sandra L. Bull
-
Patent number: 5256701Abstract: A disinfectant composition comprising an aqueous solution or an alcoholic aqueous solution in a concentration of 83 v/v % or less which contains hydroxypropyl cellulose in a concentration of from 0.5 to 10 w/v %, iodine in a concentration of from 0.01 to 1.0 w/v %, and an iodide in a concentration of not more than 0.5 w/v %. The composition has reduced skin irritation while exhibiting sufficient bactericidal and viricidal activity.Type: GrantFiled: November 19, 1991Date of Patent: October 26, 1993Assignees: Zenzo Tamura, Meiji Seika Kaisha Ltd.Inventors: Zenzo Tamura, Kuniko Shoji, Chieko Azegami, Takao Kunisada, Kaoru Hosoi, Kiwa Suzuki, Shikifumi Kitazawa
-
Patent number: 5238679Abstract: Silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are shaped from (A) a diorganopolysiloxane matrix resin; (B) a reinforcing amount of a filler material (B.sub.1) therefor and/or an organic peroxide (B.sub.2); and (C) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid or liquid state at ambient temperature.Type: GrantFiled: November 26, 1991Date of Patent: August 24, 1993Assignee: Rhone-Poulenc ChimieInventors: Guy Cyprien, Alain Fisch, Johnny Haggiage, Hugues Porte, Thierry Prazuck, Ghislaine Torres
-
Patent number: 5232914Abstract: A solid, storage-stable, germicidal, pre-iodine composition comprises in dry admixture with each other a solid oxy-compound of iodine, a solid reducing agent for the oxy-compound of iodine, and a solid desiccant used in amount sufficient to combine during the storage cycle of the composition with ambient and/or endogenous water. The oxy-compounds of iodine are iodic acid, iodine pentoxide, potassium iodate and sodium iodate. Preferred reducing agents are ascorbic acid, dihydroxy fumaric acid, the thiol sugars and cysteine. A preferred combination desiccant and iodine solvating agent is polyvinyl pyrrollidone having a molecular weight of from 10,000 to 1,000,000.The composition is storage-stable for an indefinite period. Upon the addition of water, the oxy-compound of iodine is reduced to nascent iodine, which, in application, serves its well-known germicidal function.Type: GrantFiled: March 29, 1991Date of Patent: August 3, 1993Assignee: Epitope, Inc.Inventor: Jack H. Fellman
-
Patent number: 5227161Abstract: This invention relates to a disinfecting epidermal cleaner using peroxidase, peroxide and iodide. The active components are maintained inactive until admixed in a define proportion with water. The pH at which the peroxidase is stored is between 7.0 and 9.0 and the pH of the admixture of the active components is between 3.0 and 6.5.Type: GrantFiled: April 4, 1991Date of Patent: July 13, 1993Assignee: Symbollon CorporationInventor: Jack H. Kessler
-
Patent number: 5219580Abstract: Silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are heat-shaped from (A) a thermoplastic silicone copolymer, and (B) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid state at ambient temperature.Type: GrantFiled: June 8, 1990Date of Patent: June 15, 1993Assignee: Rhone-Poulenc ChimieInventors: Ghislaine Torres, Christian Prud'Homme
-
Patent number: 5173291Abstract: An emulsion containing a substantially water resistant film-forming copolymer phase and iodine is claimed. The polymer-in-water emulsion forms a film that is a substantially fluid resistant, low tack, flexible film which adheres to skin and releases iodine to skin. The addition of iodate to emulsions having such a film-forming copolymer phase and iodine further enhances stability of the emulsion.Type: GrantFiled: September 10, 1990Date of Patent: December 22, 1992Assignee: Minnesota Mining and Manufacturing CompanyInventors: Robert H. Brink, Chi-Ming Tseng
-
Patent number: 5128136Abstract: A stabilized collagen gel is disclosed as are methods of making this collagen gel which is useful as a wound dressing to prevent dehydration of the subject being treated and infection of the wound. The collagen gel of the invention is stabilized by combining collagen (preferably in pharmaceutical grade collagen, which is atelopeptide collagen), with iodine or a composition capable of generating iodine. The collagen is flowable on first mixing and undergoes a phase transition to form a stable gel with sufficient structural integrity to form a wound dressing.Type: GrantFiled: November 4, 1991Date of Patent: July 7, 1992Assignee: The Oregon Health Sciences UniversityInventors: J. Peter Bentley, Jack H. Fellman
-
Patent number: 5126127Abstract: Povidone-Iodine (PVP-I) solutions stable according to U.S.P. standards and a method for preparing the same are disclosed. The PVP-I solution includes a microbicidal effective amount of available iodine and an alkalinizing agent in an effective amount to maintain the stability of the solution for a desired shelf-life of the solution when said solution is stored in a substantially nonpermeable container, the solution being non-buffered. In preferred embodiments, the iodophor solution is a microbicidal PVP-I solution for ophthalmic use.Type: GrantFiled: July 16, 1991Date of Patent: June 30, 1992Assignee: Euroceltique, S.A.Inventors: Dileep Bhagwat, Benjamin Oshlack
-
Patent number: 5081106Abstract: A stabilized collagen gel is disclosed as are methods of making this collagen gel which is useful as a wound dressing to prevent dehydration of the subject being treated and infection of the wound. The collagen gel of the invention is stabilized by combining collagen (preferably a pharmaceutical grade collagen, which is atelopeptide collagen), with iodine or a composition capable of generating iodine. The collagen is flowable on first mixing and undergoes a phase transition to form a stable gel with sufficient structural integrity to form a wound dressing.Type: GrantFiled: July 16, 1990Date of Patent: January 14, 1992Assignee: The Oregon Health Sciences UniversityInventors: J. Peter Bentley, Jack H. Fellman
-
Patent number: 5055287Abstract: This invention relates to a color controlled disinfecting peroxide cold sterilization composition employing an iodide salt and to a method for controlling the formation and duration of color when such composition is combined with water.Type: GrantFiled: February 3, 1988Date of Patent: October 8, 1991Inventor: Jack H. Kessler
-
Patent number: 5028458Abstract: There is disclosed an antiseptic polish for covering highly touched surfaces which contain a solution comprising Povidone-Iodine of approximately 7.5 to 10 percent by volume dispersed in a liquid polish.Type: GrantFiled: January 16, 1990Date of Patent: July 2, 1991Assignee: Warren F. B. LindsleyInventor: Fred Mineck
-
Patent number: 4978527Abstract: An emulsion containing a substantially water resistant film-forming copolymer phase and iodine is claimed. The polymer-in-water emulsion forms a film that is a substantially fluid resistant, low tack, flexible film which adheres to skin and releases iodine to skin. The addition of iodate to emulsions having such a film-forming copolymer phase and iodine further enhances stability of the emulsion.Type: GrantFiled: April 10, 1989Date of Patent: December 18, 1990Assignee: Minnesota Mining and Manufacturing CompanyInventors: Robert H. Brink, Chi-Ming Tseng
-
Patent number: 4937072Abstract: The method comprises forming a sporocide having a defined period of sporocidal activity comprising three components including a peroxide or peroxide generating material, a peroxidase and a salt of iodide which serves as a donor molecule; storing the three components in a nonreacting state to maintain the sporocide in an inactive state and admixing the three components in a aqueous based carrier to cause a catalyzed reaction by said peroxidase for generating free radicals and/or byproducts from the iodide salt (donor molecule) and contacting the surface or object to be sterilized with the activated mixture. The concentration level of the three components can be selected such that an active sporocidal state is maintained for any desired period of time.Type: GrantFiled: November 7, 1988Date of Patent: June 26, 1990Inventors: Jack H. Kessler, Robert S. Rosenbaum
-
Patent number: 4849215Abstract: The microbicidal effectiveness of pharmaceutical iodophor preparations comprising an organic substance which reacts with iodine to form a complex thereof, such as polyvinylpyrrolidone, iodine bound thereto in complex form, free iodine, and iodide ions, is assured by controlling the ratio of total iodine (complex bound iodine and free iodine) to iodide ions at between 2:1 and 10:1, this ratio being adjusted without chemical oxidizing agents such as iodate ions by anodic oxidation of a solution of the iodophor preparation and iodide ions. The resulting preparation can be free of chemical oxidizing ions such as iodate ions.Type: GrantFiled: January 9, 1987Date of Patent: July 18, 1989Assignee: Euroceltique, S.A.Inventor: Waldemar Gottardi
-
Patent number: 4847067Abstract: A mold and dust inhibiting composition which has particular utility in connection with the storage and handling of animal feeds, grains, and hay, and also in connection with the use of animal litter such as poultry litter, as well as having general utility for controlling both mold and dust. The composition of the invention is an aqueous solution of one or more salts of propionic acid, one or more deliquescent substances, and also preferably one or more humectants. Propionate ions are made available for mold control by this solution just as effectively as propionic acid, but without the disadvantages of propionic acid including a bad odor, serious corrosive characteristics, and high volatility and hence short residual time. The deliquescent, and preferably also the humectant, prevent moisture from migrating toward container walls where there is a large day/night temperature differential, and also prevent dry regions from developing and producing potentially harmful dust.Type: GrantFiled: February 26, 1988Date of Patent: July 11, 1989Inventor: Richard D. Thomas
-
Patent number: 4844899Abstract: Halophors, e.g., bromophors, comprising a complex of sulfone, e.g., sulfolane, halide ion, e.g., sodium bromide, and halogen, e.g., bromine, are described. Solid, free-flowing halophor compositions of the aforesaid complex and an amorphous siliceous carrier are also described.Type: GrantFiled: January 16, 1986Date of Patent: July 4, 1989Assignee: PPG Industries, Inc.Inventors: Robert H. Juda, Paritosh M. Chakrabarti, Roger A. Crawford
-
Patent number: RE36605Abstract: This invention relates to a disinfecting epidermal cleaner using peroxidase, peroxide and iodide. The active components are maintained inactive until admixed in a .[.define.]. .Iadd.defined .Iaddend.proportion with water. The pH at which the peroxidase is stored is between 7.0 and 9.0 and the pH of the admixture of the active components is between 3.0 and 6.5.Type: GrantFiled: November 4, 1997Date of Patent: March 7, 2000Assignee: Symboollon CorporationInventor: Jack H. Kessler