Sodium Chloride Patents (Class 424/680)
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Publication number: 20120177751Abstract: Disclosed is a non-toxic composition and methods for controlling and preventing lice infestations. The composition of the invention controls louse populations with daily use. The composition of the invention may be used on the hair, body, and on inanimate objects. The viscous liquid composition of the invention may be applied as a shampoo, body cleanser, or detergent.Type: ApplicationFiled: January 6, 2012Publication date: July 12, 2012Applicant: TEC LABORATORIES, INC.Inventors: Wendy Sue Langley, Nikki Lynn Frum, Vernon Wade Smith, Larry Mark Burris, Steven Dale Smith
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Patent number: 8216172Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolytes but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.Type: GrantFiled: November 2, 2011Date of Patent: July 10, 2012Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Peter C. Chang, Jean-Michel Lannoy
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Patent number: 8202547Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.Type: GrantFiled: January 17, 2011Date of Patent: June 19, 2012Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Dilip H. Shah, Todd Ing
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Publication number: 20120134925Abstract: The present invention relates to the uses of the protein PRG4 and therapeutic modulation thereof. In particular, the present invention relates compositions and methods utilizing PRG4 and therapeutic modulation thereof, including, use as a surgical lubricant, use in a treatment for prevention or reduction of post-surgical adhesions, use in a treatment for oral ulcerations, use as an athletic lubricating patch, use as a dermal filler, use in a treatment for dry mouth, use in a drug delivery method or composition, and use in nursing lubrication.Type: ApplicationFiled: May 24, 2010Publication date: May 31, 2012Inventors: Benjamin Sullivan, Tannin Schmidt, Edward R. Truitt, Nicole Barbara Justis Truitt, David Sullivan
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Publication number: 20120107419Abstract: A formulation and method of use for neutralizing the acidity in the mouth of a patient. The method comprises taking into the mouth an aqueous solution comprising a water soluble inorganic salt consisting of sodium and/or potassium chloride, a sodium phosphate buffer consisting of sodium monophosphate and/or sodium diphosphate and glycerin in a pH-balanced solution, maintaining the aqueous solution in the mouth for a period of time sufficient to reduce the acidity in the mouth, and thereafter spitting out the aqueous solution. The amount of sodium/potassium chloride present in the aqueous solution may be from about 0.45% to about 2.0% by weight per unit volume. The amount of sodium monophosphate in the aqueous solution may be from about 0.005% to about 0.02% by weight per unit volume, for example. The amount of sodium diphosphate in the aqueous solution may be from about 0.005% to about 0.02% by weight per unit volume. The amount of glycerin in the aqueous solution may be about 0.0005% to about 0.Type: ApplicationFiled: October 28, 2010Publication date: May 3, 2012Inventor: Raj Sadasivan
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Publication number: 20120107414Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.Type: ApplicationFiled: March 26, 2010Publication date: May 3, 2012Applicant: Pulmatrix, Inc.Inventors: Michael M. Lipp, Robert W. Clarke, David L. Hava, Richard Batycky, John Hanrahan
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Patent number: 8158157Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolites but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.Type: GrantFiled: July 7, 2010Date of Patent: April 17, 2012Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Peter C. Chang, Jean-Michael Lannoy
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Publication number: 20120087964Abstract: The present disclosure relates to water dispersible granular pesticide compositions, and methods of making and using the compositions. The pesticide compositions include an inner layer including a first pesticide coated on to a substrate, and an outer layer comprising a second pesticide coated on the inner layer. The outer layer increases the water dispersibility of the granular composition, and protects the first pesticide against hydrolysis and photolysis.Type: ApplicationFiled: October 12, 2011Publication date: April 12, 2012Applicant: ECOLAB USA INC.Inventors: Victor F. Man, Yvonne M. Killeen, Susan M. Viall
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Publication number: 20120087987Abstract: The present disclosure relates to the combined use of two pesticides. A first pesticide composition provides an initial contact kill, and may form a barrier when applied to greasy surfaces. A second pesticide composition provides residual pesticidal activity on the surface. Methods of making and using the pesticide compositions are also provided.Type: ApplicationFiled: October 12, 2011Publication date: April 12, 2012Applicant: ECOLAB USA INC.Inventors: Victor F. Man, S. John Barcay, Darren M. Jahnke, Yvonne M. Killeen
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Patent number: 8147698Abstract: The present disclosure describes novel standardized citrate replacement fluid solutions and a standardized dialysate solution for use with CRRT methods. The standardized citrate replacement fluid solutions and standardized dialysate solutions do not require modification based on the clinical status of the individual patients. The use of the standardized solutions described herein offers significant advantages over the prior art solutions used in CRRT. The present disclosure describes superior metabolic and electrolyte control and significantly increased dialyzer patency in: (a) 24 intensive care unit (ICU) patients with ARF using a 0.67% trisodium citrate replacement fluid solution, and (b) 32 ICU patients with ARF using a 0.5% trisodium citrate replacement fluid solution. Both groups were treated with Bicarbonate-25 dialysate and achieved effluent rates of 35 mL/kg/hr.Type: GrantFiled: January 20, 2011Date of Patent: April 3, 2012Assignee: The UAB Research FoundationInventors: Ashita Tolwani, Rajesh Speer, Brenda Stofan
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Publication number: 20120064126Abstract: The present invention is directed toward respirable dry particles for delivery of divalent metal cation salts and/or monovalent cation salts to the respiratory tract and methods for treating a subject having a respiratory disease and/or infection.Type: ApplicationFiled: March 26, 2010Publication date: March 15, 2012Applicant: PULMATRIX, INC.Inventors: Jean C. Sung, Michael M. Lipp
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Publication number: 20120058198Abstract: The invention relates to methods for treating bacterial infection of the respiratory tract, including pneumonias, such as ventilator-associated pneumonia, and to methods for treating ventilator-associated tracheobronchitis, comprising administering an effective amount of a salt formulation as an aerosol to the respiratory tract of an individual in need thereof. The formulations can also be used to reduce transmission of pathogen which can infect the respiratory tract, cause pneumonia or cause ventilator-associated tracheobronchitis.Type: ApplicationFiled: March 26, 2010Publication date: March 8, 2012Applicant: PULMATRIX, INC.Inventors: Robert W. Clarke, Richard Batycky, Wesley H. Dehaan, David L. Hava, Michael M. Lipp, John Hanrahan
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Publication number: 20120045525Abstract: A mosquito repellent solution to prevent mosquito bite, comprising 0.1-9.9% organic acid of total weight as active principle, 88-99.6% water as solvent. The organic acid is single acid or mixed composition out of ethyl butyrate, propionic acid, n-butyric acid, isobutyric acid, isobutyric, valeric acid, hexanoic acid, n-Heptanoic acid, L-Lactic Acid and malic acid. The composition solution to prevent mosquito bite disturb mosquitoes' olfactory sensation through imitating human's smell of skin and breath; all raw materials base on the standard of food grade, so the composition is safe to human beings, particularly to infant, pregnant women, children and the old who are weaker. The composition solution does not work by killing mosquitoes so it would not relate to resistance and ecology risk. The preparation method is simple with low costs; there is no three wastes and friendly to the environment.Type: ApplicationFiled: November 16, 2009Publication date: February 23, 2012Applicant: ZHEJIANG FORESTRY COLLEGEInventor: Jianyi Ma
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Publication number: 20120045418Abstract: The present invention relates to a topical pharmaceutical preparation for treating an inflammatory skin condition, preferably a condition associated with ischemia, comprising a supernatant of a physiological solution obtainable by cultivating peripheral blood mononuclear cells (PBMCs) or a subset thereof in a physiological solution free of PBMC-proliferating and PBMC-activating substances for at least 1 h.Type: ApplicationFiled: December 18, 2009Publication date: February 23, 2012Applicant: APOSCIENCE AGInventor: Hendrik Jan Ankersmit
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Publication number: 20120034320Abstract: The present invention comprises an all-natural composition of matter and methods of delivering nutrients, medicines, pain relievers, antioxidants, antidotes, antibiotics and various active ingredients and supplements directly to the affected area of the body. The all-natural carrier composition consists essentially of the combination of a natural oil, water, salt(s), natural emulsifier, natural sugar(s), plant extracts, natural acid(s), starch and natural flavor(s). The active substances that are mixed with the all-natural carrier composition, include, but are not limited to, drugs, vitamins, minerals, antibiotics anti fungal agents, antioxidants, diuretics, allergy medicines, anti-inflammatory agents, muscle relaxers, pain reducers, diabetic drugs, neuropathy drugs, chemotherapy agents, arthritis drugs, lotions for eczema, shingles, psoriasis, skin rash; herbal medicines, erectile dysfunction drugs, hormones, cholesterol drugs, essential fatty acids, and the like.Type: ApplicationFiled: July 15, 2011Publication date: February 9, 2012Applicant: DOMINION RESOURCES, UNLIMITED, LLCInventors: Daniel G. Murray, Michael W. McDonough
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Publication number: 20120021072Abstract: The invention features topical formulations comprising an osmotically active agent and/or a vasoconstrictor and/or an astringent agent for the treatment and prevention of eyelid swelling, and methods of use thereof.Type: ApplicationFiled: September 21, 2011Publication date: January 26, 2012Applicant: Aciex Therapeutics, Inc.Inventors: Matthew Jonathan Chapin, Mark Barry Abelson, Keith Jeffrey Lane, Akimitsu Makino
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Publication number: 20120016338Abstract: Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated.Type: ApplicationFiled: September 23, 2011Publication date: January 19, 2012Applicant: BOSTON SCIENTIC SCIMED, INC.Inventor: Joseph V. DiTrolio
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Patent number: 8057827Abstract: Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage forms comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage forms is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated.Type: GrantFiled: June 4, 2007Date of Patent: November 15, 2011Assignee: Boston Scientific Scimed, Inc.Inventor: Joseph V. DiTrolio
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Publication number: 20110268806Abstract: The present invention relates to a antisolvent solidification process wherein a liquid medium comprising at least one organic or inorganic compound which is to be solidified is forced through a membrane into one or more antisolvents, or wherein one or more antisolvents are forced through a membrane into a liquid medium comprising at least one organic or inorganic compound which is to be solidified, yielding a composition comprising solid particles comprising said organic and/or inorganic compound(s).Type: ApplicationFiled: May 3, 2011Publication date: November 3, 2011Applicant: Organon USA, Inc.Inventors: Wridzer Jan Willem Bakker, Robert Michael Geertman, Marianne Frederika Reedijk, Jozef Johannes Maria Baltussen, Gerrald Bargeman, Cornelis Elizabeth Johannus Van Lare
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Publication number: 20110262562Abstract: The invention relates to aqueous saline solutions with an osmolarity of 50 mOsm/L to 170 mOsm/L, which further include at least one membrane-weakening agent. The invention also relates to a cosmetic composition which includes one of said solutions, as well as to the use of one of said solutions to obtain a drug for treating cellulite, steatomery, and lipomas.Type: ApplicationFiled: October 27, 2009Publication date: October 27, 2011Applicant: LIPOLYANEInventors: Yves Crassas, Denis Blache
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Publication number: 20110212235Abstract: Antimicrobial formulations and solutions for food safety and quality applications are disclosed. Because some of these formulations and solutions contain a substantial concentration of salt, they are adaptable to a variety of food-processing applications, such as for chilling brine applications, disinfecting meat baths/rinses, beef injection brines, poultry chill tanks, brines used in cheese manufacture, as a wash to kill salmonella and other bacteria on hard-boiled eggs or egg shells, and as a wash to disinfect produce, which can become contaminated with salmonella and other pathogenic bacteria in the field. These uses of concentrated salt solutions that depress the freezing point of the solution provide a low temperature bath or shower in which food products can be cooled. One embodiment comprises between 25 ppm and 100,000 ppm surfactant and between 72% and 99.99% salt.Type: ApplicationFiled: September 30, 2010Publication date: September 1, 2011Inventors: Robert Scott KOEFOD, Timothy Freier
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Patent number: 7993682Abstract: The invention relates to compositions for use in purgatives, to purgatives comprising such compositions, and to methods for inducing purgation of the colon. The composition may comprise at least one water-soluble sodium salt; at least one water-soluble minimally degradable sugar in an amount, by weight, of from about 1 to about 3 times the weight of sodium ions in said composition; at least one water-soluble potassium salt in an amount, by weight, of from about 0.05 to about 1 time the weight of said sodium salt in said composition; and at least one water-soluble magnesium salt, wherein the weight of magnesium ions in said composition is from 0.1 to about 10 times the weight of sodium ions in said composition.Type: GrantFiled: March 4, 2003Date of Patent: August 9, 2011Inventors: Thomas Julius Borody, Sanjay Ramrakha, John Saxon, Antony Wettstein
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Publication number: 20110189091Abstract: The present invention provides compositions, systems, kits, and methods for preparation prior to a colonoscopy or other gastrointestinal procedure. In particular, the present invention provides a colon lavage system comprising an aqueous portion and a solid portion.Type: ApplicationFiled: April 20, 2010Publication date: August 4, 2011Inventor: Dale R. Bachwich
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Publication number: 20110171324Abstract: The invention is directed to a method of a method of treating or preventing disease in honeybees, a method of promoting the health of honey bees and to a method of increasing the production of honeybees in a hive or colony.Type: ApplicationFiled: January 14, 2010Publication date: July 14, 2011Inventor: Richard William Clemente
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Publication number: 20110171271Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.Type: ApplicationFiled: January 17, 2011Publication date: July 14, 2011Applicant: HHD LLCInventors: Dilip H. Shah, Todd Ing
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Patent number: 7976876Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) a mixture of a coenzyme having reducing ability and a quinone, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: GrantFiled: September 29, 2008Date of Patent: July 12, 2011Assignee: Well-Being Biochemical Corp.Inventors: Jih-ru Hwu, Shwu-chen Tsay
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Publication number: 20110142962Abstract: The present disclosure is directed to oral rehydration solutions, and the use of these solutions to prevent dehydration due to fever. The oral rehydration solutions of the present disclosure may be oral rehydration solutions comprising about 12 mEq/L to about 18 mEq/L of sodium, from about 11 g/L to about 60 g/L of dextrose, a zinc source, and less than about 25 mEq/L of citrates. The pH of the oral rehydration solutions can be controlled by adjusting the amount of dextrose present in the oral rehydration solutions, allowing for formulation of oral rehydration solutions comprising lower levels of citrates.Type: ApplicationFiled: November 19, 2010Publication date: June 16, 2011Inventors: Steven T. Luebbers, Julie J. Chio, Pedro A. Alarcon
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Publication number: 20110135757Abstract: A method for disinfection of a contaminated enclosed facility with microaerosol containing free radicals produced from an electrochemically-activated solution. In one embodiment of the invention the aerosol is produced from the EAS and air mixture at the air:EAS ratio (1-10):1 (by mass) with the droplets of ?10 ?m. This method is preferably performed by the atomization of the mixture with a vortex ejector nozzle with subsequent separation of coarsely dispersed particles.Type: ApplicationFiled: June 26, 2009Publication date: June 9, 2011Inventors: Evgeniyi Sventitskyi, Valeryi Giushchenko, Yury Tqiparoy, Elene Chemyaeva, Victor Iskritsky
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Patent number: 7943165Abstract: The present invention generally relates to a wet wipe or sheet that is suitable for contacting the skin and removing mucus from the skin. More specifically, the present invention relates to a wet wipe having an aqueous saline component suitable for dissolving and removing mucus in combination with the fabric matrix of the wet wipe. Typically, the fabric matrix of the wet wipe has a capacity of about 125 grams of solution per square meter, and it is impregnated with the aqueous saline solution to a level at or below approximately 80% of the absorbent capacity of the matrix.Type: GrantFiled: August 11, 2008Date of Patent: May 17, 2011Assignee: Little Busy Bodies, Inc.Inventors: Mindee K. Doney, Julienne M. Pickens
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Publication number: 20110111060Abstract: The present invention provides effective novel compositions and formulations for treating and/or preventing a hangover. The present invention also provides methods for treating and/or preventing a hangover comprising administering the compositions and/or formulations of the present invention.Type: ApplicationFiled: June 24, 2009Publication date: May 12, 2011Inventor: Andrew R. Chadeayne
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Publication number: 20110104300Abstract: The invention provides methods and kits for screening a test agent for antiviral activity against Norovirus. The methods are effective in terms of determining the amount of intact Norovirus while decreasing the amount of interfering RNA and PCR inhibitors within the test sample.Type: ApplicationFiled: September 28, 2010Publication date: May 5, 2011Applicant: KIM LABORATORIES, INC.Inventors: Myung L. Kim, David J. Schlesinger
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Publication number: 20110097396Abstract: A cosmetic capsule which can be topically applied and rubbed in and comprises a casing material and a filling material enclosed by the casing material. The casing material is composed of an emulsion which comprises one or more waxes that are solid above 25° C. and the filling material comprising a preparation which has an abrasive effect and comprises one or more abrasive peeling agents which are present in an oil or lipid mixture, a surfactant-containing preparation or an emulsion.Type: ApplicationFiled: September 12, 2007Publication date: April 28, 2011Inventors: Svea Wischhoefer, Nils Hoffmann, Silke Weyland, Jessica Schaefer
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Publication number: 20110086114Abstract: A nasal spray solution for use as a nasal spray and methods of using the solution are disclosed. The nasal spray solution moisturizes nasal passages and alleviates nasal dryness. The solution includes a hypotonic saline solution, wherein the saline solution is hypotonic with respect to cells of the nasal mucosa of the nasal passages, a buffering agent, a lubricating agent, and an anti-microbial agent.Type: ApplicationFiled: September 20, 2010Publication date: April 14, 2011Inventors: James ZINREICH, Eva ZINREICH, Helen Zinreich SHAFER
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Patent number: 7910090Abstract: The present invention provides a base composition that allows for the formulation of non-irritating cosmetic and/or dermatological compositions. The base composition includes one or more of electrolyte, buffer, mild preservative, lubricant, or any combinations thereof. It is preferred that one or more of the above components are eye-safe and/or eye-compatible. The present invention also provides photoprotective cosmetic and/or dermatological compositions that include the base composition and one or more sunscreen active components and are non-irritating to mammalian eyes.Type: GrantFiled: January 18, 2006Date of Patent: March 22, 2011Assignee: Playtex Products, Inc.Inventors: Olga V. Dueva-Koganov, James P. SaNogueira
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Publication number: 20110052656Abstract: A process has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex biofilm matrices through the use of liposome carriers, thereby removing the biofouling in industrial water bearing systems, including piping, heat exchanges, condensers, filtration systems and fluid storage tanks. According to one embodiment of the invention, antimicrobial compound containing liposomes are added to water systems prone to biofouling and biofilm formation. The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the existing biofilm. Once the antimicrobial compound containing liposomes become entrained with the biofilm matrix, the decomposition or programmed disintegration of the liposome proceeds. Thereafter, the biocidal aqueous core is released to react directly with the biofilm encased microorganisms.Type: ApplicationFiled: September 28, 2010Publication date: March 3, 2011Applicant: GENERAL ELECTRIC COMPANYInventors: Wilson Kurt Whitekettle, Gloria Jean Tafel, Qing Zhao, Linna Wang, Dorothy Reynolds, Paul Frail, Juan Jiang, David M. Polizzotti
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Patent number: 7897779Abstract: The present invention relates to novel 1,4-dihydropyridine derivatives, to novel cosmetic or dermatological sunscreen compositions containing these derivatives and the use of these derivatives for photoprotecting human skin and/or hair against UV radiation, in particular solar radiation.Type: GrantFiled: February 11, 2005Date of Patent: March 1, 2011Assignee: DSM IP Assets B.V.Inventors: Katja Berg-Schultz, Ulrich Huber, Daniel Sprenger
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Patent number: 7883725Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.Type: GrantFiled: May 29, 2009Date of Patent: February 8, 2011Assignee: HHD LLCInventors: Dilip H. Shah, Todd Ing
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Patent number: 7884132Abstract: The present disclosure describes novel standardized citrate replacement fluid solutions and a standardized dialysate solution for use with CRRT methods. The standardized citrate replacement fluid solutions and standardized dialysate solutions do not require modification based on the clinical status of the individual patients. The use of the standardized solutions described herein offers significant advantages over the prior art solutions used in CRRT. The present disclosure describes superior metabolic and electrolyte control and significantly increased dialyzer patency in: (a) 24 intensive care unit (ICU) patients with ARF using a 0.67% trisodium citrate replacement fluid solution, and (b) 32 ICU patients with ARF using a 0.5% trisodium citrate replacement fluid solution. Both groups were treated with Bicarbonate-25 dialysate and achieved effluent rates of 35 mL/kg/hr.Type: GrantFiled: November 14, 2005Date of Patent: February 8, 2011Assignee: The UAB Research FoundationInventors: Ashita Tolwani, Rajesh Speer, Brenda Stofan
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Patent number: 7858124Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.Type: GrantFiled: April 7, 2008Date of Patent: December 28, 2010Assignee: Well-Being Biochemical Corp.Inventors: Jih Ru Hwu, Shwu Chen Tsay
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Publication number: 20100319725Abstract: Inventive methods, systems and compositions for sanitizing food products are described. A method for sanitizing food products includes: (a) activating a solution, which includes a solute and a solvent, by using acoustic energy to form a coherent solution including solute clusters, in which each solute cluster is organized such that at least one solute molecule is surrounded by many solvent molecules; and (b) submerging the food products into a tank containing the coherent solution to sanitize the food products.Type: ApplicationFiled: June 18, 2009Publication date: December 23, 2010Applicant: NANO OM TECHNOLOGY, LLCInventors: Suraj Puri, George Plaut, Saurabh Sharma
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Publication number: 20100297264Abstract: The present invention is directed to a dry composition for admixture with water for oral administration to a mammal and methods of using the composition for cleansing the bowel of a mammal in need thereof.Type: ApplicationFiled: October 16, 2008Publication date: November 25, 2010Applicant: THOMAS JEFFERSON UNIVERSITYInventor: David Kastenberg
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Publication number: 20100284951Abstract: The present invention provides novel compositions which comprise sodium hypochlorite, sodium, chloride, both organic and inorganic trace minerals in hypertonic condition presented in the forms of a clear aqueous solution (low or high concentrations for further reconstitution with purified water to obtain the final ready-to-use solution), gel or salve, lotion, wet pad, wet foam, ointment, stick, and dry mixture solution, for local application for the purposes of cleansing, disinfecting and inhibiting infection and promoting the natural healing of conditions such as fresh cuts, surgical stitches, chronic (diabetic gangrene) and acute wounds, herpes zoster, athlete's foot, and bed sores, without the necessity for covering up the wounds with gauzes/plasters nor any concurrent use of topical medication. These compositions are also suitable for the treatment of conditions such as unpleasant body odor, acne and mixed bacterial infection in the ear.Type: ApplicationFiled: May 7, 2009Publication date: November 11, 2010Inventors: Thavisith Pongprapansiri, Pensri Chatikavanit, Somchai Boonchuen
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Publication number: 20100233295Abstract: This application relates to water-based personal moisturizers and lubricants that relive vaginal dryness. These compositions are non-spermicidal, sperm- and egg-friendly, and in various embodiments may mimic biological fluids, enhance sperm survival and motility, promote binding of sperm to eggs, and/or facilitate the process of fertilization. Related articles, systems, and methods of preparation and use of the compositions are also provided.Type: ApplicationFiled: February 28, 2007Publication date: September 16, 2010Inventors: Vibha Gupta, Vineet Gupta, Boris Nikolic
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Publication number: 20100226867Abstract: The present invention provides a base composition that allows for the formulation of non-irritating cosmetic and/or dermatological compositions. The base composition includes one or more of electrolyte, buffer, mild preservative, lubricant, or any combinations thereof. It is preferred that one or more of the above components are eye-safe and/or eye-compatible. The present invention also provides photoprotective cosmetic and/or dermatological compositions that include the base composition and one or more sunscreen active components and are non-irritating to mammalian eyes.Type: ApplicationFiled: May 17, 2010Publication date: September 9, 2010Inventors: Olga V. Dueva-Koganov, James P. SaNogueira
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Publication number: 20100209540Abstract: A composition for the treatment and prophylactic management of bacterial and fungal respiratory infections is provided. The composition may contain a combination of a quaternary ammonium compound and hypertonic saline to be administered to a patient in need thereof.Type: ApplicationFiled: November 5, 2009Publication date: August 19, 2010Applicant: PharmaCaribeInventors: W. Randolph WARNER, Werner Gutmann
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Publication number: 20100196513Abstract: A composition comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected form the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavourings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.Type: ApplicationFiled: April 5, 2010Publication date: August 5, 2010Applicant: NORGINE BVInventors: Norman Barras, Ian David Cox, Alex Ungar, Marc Halphen
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Publication number: 20100191219Abstract: A catheter lock composition for preventing bacterial infection having an effective amount of glycerol and sodium chloride solution. The effective amount of glycerol is between about 35-60% and sodium chloride is in a concentration range between 0.5-0.9%. The composition further includes an anticoagulant and/or an antimicrobial agent.Type: ApplicationFiled: January 26, 2010Publication date: July 29, 2010Applicant: TELEFLEX MEDICAL INCORPORATEDInventors: Nisha Gupta, Elaine Steinke, Erin Peters, Joel Rosenblatt
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Publication number: 20100189752Abstract: A pelleted mineral supplement for land animals is provided. Each of the pellets is a cohesive mass of mineral components that when consumed by a land animal promotes the health and/or growth of the animal, and each of the cohesive masses has a largest dimension less than 0.5 inches. In certain aspects of the invention, the pelleted mineral supplement can be combined with a conventional animal feed to provide a mineral-supplemented animal feed.Type: ApplicationFiled: April 5, 2010Publication date: July 29, 2010Inventors: Haig H. Kassouni, Armen S. Kassouni
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Publication number: 20100189815Abstract: A composition comprising, per litre of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected from the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavourings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.Type: ApplicationFiled: April 5, 2010Publication date: July 29, 2010Applicant: NORGINE BVInventors: Norman Barras, Ian David Cox, Alex Ungar, Marc Halphen
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Publication number: 20100183736Abstract: The present invention relates to a composition for the relief of hangover symptoms and methods of treating hangover symptoms.Type: ApplicationFiled: August 8, 2007Publication date: July 22, 2010Inventor: Evan Hays