Abstract: The present invention relates to a preservative or antimicrobial compositions which comprise low concentrations of botanical extracts, in synergistic combinations with alkanediols in a solvent system, optionally with fruit acids. Additionally, the present invention relates to a preservative or antimicrobial compositions which comprise a silver compound, an essential oil or individual constituent, one or more zinc salts, and one or more alkanediol. The compositions of the invention may be used in personal care products including wound care products or in veterinary use. Preferably, the compositions of the invention have little or no human-detectable fragrance.

Abstract: Disclosed herein is a method of using megestrol acetate. In one embodiment, the method comprises informing a user that megestrol acetate is metabolized by a cytochrome p450 isozyme. In another embodiment, the method comprises obtaining megestrol acetate from a container associated with published material providing information is metabolized by a cytochrome p450 siozyme. Also disclosed are articles of manufacture comprising a container containing a dosage form of megestrol acetate, wherein the container is associated with published material informing that megestrol acetate is metabolized by a cytochrome p450 siozyme, a method of treatment, and a method of manufacturing a megestrol acetate product.

Abstract: A cosmetic or pharmaceutical rinse-off formulation contains 0.2% by weight to 20% by weight of a phase A; 0.1% by weight to 50% by weight of an active substance; a detergent; and the remainder being water. The phase A is a mixture of 20% by weight to 90% by weight of a surfactant mixture of isethionates, acyl lactylates and one of alkyl glutamates and alkyl glucosides and 10% by weight to 80% by weight of water, alcohol, polyol or mixtures thereof. The phase A forms multilamellar vesicles. The cosmetic or pharmaceutical rinse-off formulation is a clear product with the multilamellar vesicles of phase A having an average diameter of less than 100 nm.

Abstract: Provided are a polyphenol compound absorption promoter which is widely applicable to foods and drinks over a wide range, and a method for producing a food, drink or food material containing a polyphenol compound. The polyphenol compound absorption promoter comprises, as the active ingredient, at least one member selected from the group consisting of serine, aspartic acid, malic acid, capric acid, lauric acid, grapefruit juice and Camellia sinensis (L.) O. Kuntze extract. The method for producing a food, drink or food material containing a polyphenol compound comprises: adding at least one member selected from the group consisting of serine, aspartic acid, malic acid, capric acid, lauric acid, grapefruit juice and Camellia sinensis (L.) O.

Abstract: A multipurpose cleaning composition. The composition is a mixture of therapeutic grade essential oils, distilled white vinegar, and purified water that disinfects, degreases, and deodorizes, and also provides bioseptic and therapeutic benefits. Also provided is a method of disinfecting a surface by shaking a spray bottle having the composition, spraying the composition on the surface to be disinfected, allowing the composition to remain in contact with the surface for an amount of time sufficient to disinfect the surface, and removing the composition by wiping with a cloth. Essential oils may include, but are not limited to, therapeutic grade essential oils of eucalyptus, lemon, lavender, and grapefruit.

Abstract: The present invention provide edible compositions comprising soluble and insoluble dietary fibers at a ratio of about 1:1 ratio, having a palatable taste, useful for reducing the serum lipid content in a mammal, and further for reducing the blood glucose level, enhancing the feeling of satiety and keeping a desired body weight.

Abstract: Pharmaceutical compositions are for administration to the nasal tract. In particular, dry powder compositions are cellulose, and in particular hydroxypropylmethylcellulose (HPMC), and one or more therapeutic agents. It has been shown that administration of HPMC to the nasal cavity is capable of enhancing natural mucus. These powders, and the gel that forms when they are administered to the nasal tract, have now surprisingly been found to be a very effective way of intranasally administering therapeutic agents, and in particular, herbal or homeopathic agents.

Abstract: According to one embodiment, a coagulant comprising calcium nitrate and an antimicrobial agent is disclosed. The coagulant may be used in the molding process to releasably bond the substrate material to the mold and to bond to the antimicrobial to the substrate material.

Abstract: A herbal treatment for Diabetes Mellitus, Type II comprises a first volume of herbal oils and a first weight of ground herbs. The mixture of the oil and ground herbs forms a paste, which is dispensed in a gel capsule.

Abstract: The present invention provides a method for suppressing and relieving itching and inflammation, by administering to a host in need of such treatment an effective amount of the pharmaceutical composition containing highly lipophilic polyalkoxyflavonoid. The pharmaceutical composition and functional food of the present invention for suppressing and relieving itching and inflammation contain highly lipophilic polyalkoxyflavonoid extracted from squeezed juice of a whole portion of a citrus fruit (inclusive of pericarp thereof). Furthermore, the functional food of the present invention contains it.

Abstract: The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical is a ghrelin production promoter comprising Rikkunshi-to as the active ingredient.

Abstract: A new, novel and useful disinfection and purification system comprised of organic compounds in synergistic action with selected metal ions and method of manufacture and use. One of the benefits that is derived from this system is the ability to quickly and easily treat a surface, fluid or medium for disinfection of bacteria, fungi, viruses, algae and protozoans, with a non-toxic, non-chlorinated mixture that effectively kills all such organisms in minutes or hours. The disinfection and purification system remains effective for long periods of time maintaining its disinfection capacity making it highly effective for stored or transported mediums such as potable drinking water. The disinfection and purification system may be incorporated with carbon block or membrane filters to disinfect filtered liquids such as water to render it potable.

Abstract: Disclosed is a method for the production of a diet food with medicinal herbs. According to the method, herbs which have physiological activities suitable for dieting are selected by making reference to various reports and through experimentation. Depending on nutritional and pharmaceutical ingredients responsible for the physiological functions and activities, the herbs are classified into three groups, and combined with each other to form a composition which is extracted in such a manner that as few effective ingredients are lost as possible. The diet food is effective for the prevention and treatment of obesity.

Abstract: Lipid compositions comprising nuts, seeds, oils, legumes, fruits, grains, and dairy useful in specified amounts as dietary supplements and diet plans designed around and including the aforementioned for the prophylaxis and treatment of numerous diseases are disclosed. The compositions include omega-6 and omega-3 fatty acids where the ratio of the omega-6 to the omega-3 fatty acids and their amounts are controlled based on one or more factors including age of the subject, sex of the subject, diet of the subject, the body weight of the subject, medical conditions of the subject, and climate of the subject's living area.

Abstract: Antimicrobial (e.g., moldicide, fungicide, bacteriacide, and virucide) compositions are disclosed. Methods of making and using antimicrobial (e.g., moldicide, fungicide, bacteriacide, and virucide) compositions are also disclosed.

Abstract: Compositions for treating erectile dysfunction (“ED”), including age related erectile dysfunction (ARED), comprise in a preferred embodiment ginger and an amino acid. Preferably the amino acid is L-arginine and/or L-citrulline. Additionally, the compositions may comprise cortex magnoliae officinalis (CMO) and/or fructus aurantil immaturus (FAI). The compositions of the present inventions are administered in a pharmaceutically effective amount to treat erectile dysfunction. For patients that have noticeable symptoms of ED or for older males, whether or not symptomatic, preferred compositions comprises ginger, L-arginine and/or L-citrulline, CMO, FAI, Paullinia cupana, and Muira puama.

Abstract: Emulsions, emulsifier, a method of use and a production process of said emulsions are presented in the present invention. The emulsion composed of a mixture of water and oils and additives sheared into small droplets using a low pressure, three shearing stage emulsifier. The oils used in the preparation of said emulsions are botanical oils and in most cases, edible oils.

Abstract: A eutectic-based self-nanoemulsified drug delivery system (SNEDDS) is formulated from polyoxyl 35 castor oil (Cremophor), medium chain mono- and diglycerides (capmul), essential oils, and a pharmacologically effective drug. The preferred pharmacologically effective drug is a poorly water soluble drug, such as ubiquinone (CoQ10). The SNEDDS can be further incorporated into a powder to produce a solid dosage form. The solid dosage form contains the SNEDDS, a copolymer of vinylpyrrolidone and vinyl acetate (Kollidon VA 64), maltodextrin, and microcrystalline cellulose (MCC).

Abstract: A dietary supplement composition comprising aronia extract containing at least 20% anthocyanins by dry weight. The aronia extract is derived from the aronia melanocarpa plant. The aronia extract comprises approximately 10%-30% of the dry weight of the composition. A vitamin, weight loss agent, or antioxidant is provided in the composition. The dietary supplement composition is administered orally to promote weight loss.

Abstract: Antioxidant skin care composition comprising at least two antioxidant components one of which is a solid coffee extract antioxidant, which exhibits a synergistically increased antioxidant potency as measured by ORACsc compared to the antioxidant potency of antioxidant skin care compositions which do not contain at least two antioxidant components one of which is a solid coffee extract antioxidant. The skin care compositions are particularly suited for use in the treatment of wrinkles, pigmentation effects caused by sun damage and redness in the skin.

Abstract: Disinfecting compositions having tuberculocidal and fungicidal efficacies for disinfecting and sanitizing inanimate surfaces is provided. The disinfecting compositions contain thyme oil or thyme oil and origanum oil, a salt of a transition metal, a biobased surfactant and water. This improved disinfecting composition is botanical, environmentally sustainable, non-toxic, mildly scented and highly stable.

Abstract: The present teachings provide methods for stimulating the hair growth on a human head including simultaneous administration: a) by oral or transdermal route of a composition containing a 5-alpha-reductase inhibitor or a peripheral vasodilator, and b) by topical route of a composition containing as active ingredient an extract of Allium species, an extract of Citrus species and either an extract of Paullinia species and an extract of Theobroma species or an extract of Salix species and zinc sulfate.

Abstract: Disclosed herein is a fragrance composition which contains natural oils, including rose oil and sandalwood oil, and has a good sleep-inducing effect. More specifically, disclosed is a fragrance composition which contains rose oil, sandalwood oil, neroli oil and ylang-ylang oil and creates a comfortable sleeping environment using the good sleep-inducing effects of the natural fragrance oils.

Abstract: A weight loss product comprises a mixture of Alchemilla vulgaris, Olea europaea, Cuminum cyminum, and Mentha longiflora (in the weight proportion 12:10:5:4), to which additional ingredients have been added to increase weight loss efficacy.

Abstract: The present invention provides novel methods of applying pesticides to control pests with reduced phytotoxicity effects. The method comprises applying pesticides as micro-droplets in a low volume but high concentration.

Abstract: The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.

Abstract: The insecticide comprises an insecticide particularly for killing bed bugs comprising nanospheres and primary ingredients of Organic Andirobia, Orange, Citronella, Organic Neem and Australian Myrtle oils. The insecticide can further comprise Isopropyl Alcohol as a carrier, Phenoxyethanol, Lavandox and Leucojum Aestivum Bulb Extract.

Abstract: A natural color is concentrated to intensify color range and to provide useful amounts of one or more of anti-oxidant, nutritional, and anti-inflammatory compounds derived from one or more pigment sources. In a preferred embodiment, the pigment source is a fruit, a vegetable, a legume, a spice, algae, or a combination thereof.

Abstract: Disclosed is a perfume composition including grapefruit oil and bergamot oil and further including one or more selected from a group consisting of pine oil, lemon oil, cypress oil, rose oil and armoise oil. The perfume composition is useful in the field of beauty care, cosmetics, or the like.

Abstract: The purpose is to prevent, ameliorate or relieve various conditions induced in the dried oral cavity or to improve the stability of a denture during use. A solution for treating a denture or a denture stabilizer comprising sericin can be used.

Abstract: To date no over-the-counter, non-toxic, self-use products like Feminine Fresh All Day have been offered to women who desire a quick external cleansing method for the feminine reproductive area after urination (refer to document “Patent Search”). Currently, materials on the market include varieties of self-use wipes for external use that are either caustic, alcohol based, and/or other prescriptive internal applicators with associated chemical mixtures, solutions and concoctions to be used when infections, hormonal dysfunction, or age related dryness is present. While these internal applications may have a higher value when those conditions are present, our invention purports that frequent external cleanings after urinating, using commonly known herbal and natural antibacterial phytochemical properties may help prevent the consequence of infections as a product of residual buildup of external bacteria after urination.

Abstract: Disclosed is a method of increasing firmness or elasticity or reducing the appearance of sagginess in the periorbital area of a person's skin, comprising topically applying to the skin in need thereof a composition comprising magnolia extract and citrus grandis extract.

Abstract: A formulation includes water, shea butter, an emulsifier and an essential oil comprising myrrh. In addition, the formulation can include cocoa butter, coconut oil, kelp powder, and a preservative comprising a mixture of phenoxyethanol, methylparaben, ethylparaben, propylparaben and butylparaben. The formulation can be used for cosmetic applications in which the formulation is applied as a cream to a user's skin.

Abstract: The present invention relates to home and personal care compositions comprising a silicone oil-in-water emulsion stabilized by a protein or peptide and at least one home and/or personal care ingredient. Such compositions tend to provide desirable characteristics for the care and conditioning of hair, skin and fabric.

Abstract: The present invention refers to pharmaceutical, dietary and/or nutraceutical orosoluble and/or effervescent compositions for oral use containing at least a salt of S-adenosyl methionine (SAMe), combined with physiologically acceptable excipients and optionally additional active ingredients. In particular the invention refers to compositions with high palatability formulated in tablet, capsule or granules. The present invention also refers to the use of at least a salt of SAMe combined with physiologically acceptable excipients and optionally further active ingredients for treating, human or veterinarian, neuropsychiatric, osteoarticular or hepatic diseases.

Abstract: The present invention relates to dermal patches comprising natural polysaccharides without the need for any pressure sensitive synthetic polymers. Particularly, the present invention relates to patches comprising a bioadhesive composition comprising a polysaccharide exudate and an essential oil useful for transdermal delivery of therapeutic or cosmetic agents.

Abstract: Disclosed herein is a method of using megestrol acetate. In one embodiment, the method comprises informing a user that megestrol acetate is metabolized by a cytochrome p450 isozyme. In another embodiment, the method comprises obtaining megestrol acetate from a container associated with published material providing information is metabolized by a cytochrome p450 isozyme. Also disclosed are articles of manufacture comprising a container containing a dosage form of megestrol acetate, wherein the container is associated with published material informing that megestrol acetate is metabolized by a cytochrome p450 isozyme, a method of treatment, and a method of manufacturing a megestrol acetate product.

Abstract: A substantially non-aqueous, aerated composition is free of petroleum-based components and is suitable for skin applications. The composition primarily includes wax and oil, and can further include vitamin E oil and an essential oil. The composition can be a semi-solid at room temperature. A method of making the composition includes melting together component ingredients to form a mixture, which is then cooled to form hardened matter. The hardened matter is blended to form a flowable mixture, which is then forced through a sieve to form the aerated composition.

Abstract: Novel, environmentally safe compositions for the control of pests and methods of using these compositions are disclosed. The compositions may comprise one or more high terpene (50% by weight or more) based oils, such as but not limited to citrus oil, surfactants and other ingredients disclosed herein. Preferably, the one or more high terpene (50% by weight or more) based oils, such as but not limited to citrus oil, is cold pressed orange oil.

Abstract: Various compositions and methods are provided to alleviate one or more symptoms associated with hyposalivation or xerostomia. Preferred compositions and methods employ one or more plant extracts and/or a proanthocyanidin at a concentration effective to reduce or eliminate the symptoms. Especially preferred extracts are isolated from a fruit and/or seed (e.g., grape, cranberry, blue berry, black berry, etc.), and where a second extract is present, such extract is preferably isolated from a citrus fruit (e.g., lemon, orange, lime, grapefruit, tangerine, mandarin orange, ugli fruit, etc.).

Abstract: Provided are methods for extracting flavor and fragrance materials from natural plant materials, using poly(trimethylene ether) glycol homopolymers and copolymers. The poly(trimethylene ether) glycol homopolymers and copolymers act as solubilizers for essential oils, and can be used to provide compositions having a variety of uses in applications such as cosmetics, personal care products, and industrial cleaning products.

Abstract: Synergistic chemical compositions of bioactive compounds in a dietary supplement for lowering the risks of Alzheimer's, Cardiovascular and Diabetes diseases; chemical compositions of a sugar free super sweetener for people with Type-2 Diabetes disease and a targeted nano delivery of bioactive compounds and/or bioactive molecules are described. Furthermore, microelectro-mechanical system (Mems) based passive and active (based on feedback diagnostics data) delivery systems and methods of bioactive compounds and/or bioactive molecules are also described.

Abstract: An oil-based composition for application to mucosal surfaces of the human body provides potent activators of cytoprotective antioxidants. The composition includes the following ingredients: soy oil; coconut oil; orange oil; peppermint oil; aloe vera oil; vitamin E; and may further include jojoba and a preservative. Application of the composition increases expression of antioxidant genes and inhibits proinflammatory action caused by exposure to oxidant pollutants, allergens and other cytotoxins.

Abstract: This invention relates to improved solutions comprising ascorbic acid (vitamin C). These solutions may comprise as much as 15% ascorbic acid; they are stable for at least two years, without no significant development of yellowish coloration and no substantial (not more than 10%) degradation of the vitamin. The process involves sequential additions of ascorbic acid and ethoxydiglycol to a first solution of vitamin in water, which are followed by addition of propylene glycol. The high stirring speed that occurs during the additions favors a process of micronization. Mild heating is used to achieve ascorbic acid concentrations equivalent to about 6% in 10% water or higher.

Abstract: An improved composition for skin cleansing and protection is disclosed. The composition contains an effective amount of at least one alpha-hydroxyl acid or a pharmaceutically acceptable salt thereof, at least one base, one surfactant and one skin protectant. Various additives and excipients may be included in the formulation. The improved composition disclosed herein achieves a higher bacteria killing rate and shows longer action duration. The disclosed composition is capable of penetrating deep into the skin which allows for delivery of more anti-microbials to sites that are at a higher risk of being infected. Various modifications of the improved composition are also disclosed.

Abstract: The present invention provides novel herbal nano emulsion based formulations comprising a combination of lemon juice and/or rose water as therapeutically active aqueous phase entrapped in oil phase selected from one or more essential oils and process for the preparation of the same in pharmaceutically acceptable dosage forms for topical treatment of acne and other skin disorder like eczema, psoriasis, aging scaring and the like with increased efficacy, Improved percutaneous penetration, excellent thermodynamic stability ensuring long shelf life, low skin irritation and reservoir effect that promotes drug localization in the skin enabling controlled delivery of the said therapeutic agents.

Abstract: The liquid composition of the present invention contains 0.01 to 1 wt % of a nonionic surfactant (a), 0.05 to 1 wt % of a dihydric alcohol having 2 to 4 carbon atoms (b), and 30 to 70 wt % of ethanol (c), the nonionic surfactant (a) is at least one selected from the group consisting of alkyl ether type nonionic surfactants and polyoxyethylene hydrogenated castor oil type nonionic surfactants, the mole number of ethylene oxide per mole of the nonionic surfactant (a) being 20 to 100, and the HLB value of the nonionic surfactant (a) being 13 to 20.

Abstract: A bioluminescence imaging-based high-throughput assay for inhibitors of ABCG2 is described. Compositions of inhibitors of ABCG2 and methods of using ABCG2 inhibitors are also described.

Abstract: The object of the invention is the use in a cosmetic composition of an effective amount of at least one cutaneous cell autophagy activator as a cosmetic active ingredient. The invention also relates to cosmetic compositions that include at least one cutaneous cell autophagy activator as a cosmetic active ingredient 5 and a cosmetic process for detoxifying skin and/or for preventing or combating cutaneous aging.

Abstract: The invention provides a solid, self-bioadhesive composition for topical application that adheres to the oral mucosal tissue comprising a therapeutically effective amount of at least one herbal or homeopathic active agent; and a pharmaceutically acceptable solid bioadhesive carrier in an amount from about 40 to 99 percent based on the weight of the whole composition.