Containing Or Obtained From Ginkgo (e.g., Ginkgo Biloba, Maidenhair, Etc.) Patents (Class 424/752)
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Publication number: 20070231279Abstract: A cosmetic self-tanning composition which comprises dihydroxyacetone and a ginkgo extract and/or grapeseed oil and/or a lotus blossom extract. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.Type: ApplicationFiled: July 11, 2006Publication date: October 4, 2007Applicant: BEIERSDORF AGInventors: Jens Schulz, Corina Zu Putlitz, Stephanie Von Der Fecht, Katja Luettig, Rainer Kroepke
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Patent number: 7264828Abstract: The process of extracting small molecular ingredients from biological materials under super high pressure is a process which makes use of super high pressure to extract small molecular active ingredients from biological materials, especially natural products, which mainly consists of extracting the mixture of solid raw material and extraction solvent under increased pressure. Said process comprises the following steps: the step of pretreatment, crash and formulation; the step of closure, charging the formulated mixture of raw material and extraction solvent into high pressure container, then closing the high pressure container; the step of increasing pressure, increasing the pressure of the high pressure container from 100 Mpa to the predefined pressure of 1000 Mpa; the step of holding pressure, holding the predefined pressure for 3-30 minutes; the step of releasing pressure, releasing the pressure of the high pressure container to normal pressure, removing the mixture.Type: GrantFiled: December 30, 2002Date of Patent: September 4, 2007Inventor: Shouqin Zhang
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Patent number: 7238375Abstract: This invention relates to a composition of matter for producing hair growth and preventing hair loss in humans and the method for using said composition. The composition comprises four complexes and a carrier liquid, mixed together and added to any topical treatment or produced as an ingestible dietary supplement. Complexes 1, 2, and 3 are comprised of substances that prevent hair loss while Complex 4 promotes hair growth. Complex 1 is comprised of octyl butyrate and glutaminpeptides. Complex 2 comprises a mixture of minerals, plant extracts, vitamin B6, and linolenic acid. Complex 3 comprises a mixture of Ginkgo biloba extract, emu oil, a source of silicon, and a blend of amino acids. Complex 4 comprises a mixture of several plant extracts. The product should be used by the consumer at regular intervals, preferably 5 to 7 times per week in the form of a serum.Type: GrantFiled: December 20, 2004Date of Patent: July 3, 2007Inventor: Stephen C. Perry
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Patent number: 7235266Abstract: Disclosed are a facial pack composition and a bathing composition based on loess, and methods for preparing the same. The bathing composition makes a user feel refreshed, prevents arteriosclerosis and fat accumulation in human bodies, is useful for the treatment of maturating diseases such as dermatophytosis and dermatitis and stimulates metabolism and blood circulation system of the human body. Additionally, the facial pack includes loess having a fine particle size sufficient to avoid skin irritation and thus does not adversely affect the skin even if the user uses the pack everyday. The loess is pretreated by a unique aging method and selected additives, so that the far infrared ray-emitting effect of the loess can be maximized. Therefore, it provides skin health-aid and cosmetic effects.Type: GrantFiled: January 9, 2006Date of Patent: June 26, 2007Inventor: Jang Yong Park
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Patent number: 7232580Abstract: A method of treating sarcopenia in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of an extract of Ginkgo biloba comprising from 5.5 to 8% in total of ginkgolides A, B, C and J, from 40 to 60% of flavoneglycosides and from 5 to 7% of bilobalide sufficient to treat sarcopenia.Type: GrantFiled: January 12, 2006Date of Patent: June 19, 2007Inventor: Yves Christen
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Patent number: 7229649Abstract: The invention provides methods and compositions for maintaining a state of wellness in a human by providing a dietary supplement comprising L-arginine, alone or in combination with ginseng and ginkgo biloba and/or additional nutritional supplements. The invention provides a unique blend of components that, in combination, synergistically bestow sexual wellness upon a human when taken regularly as a dietary supplement.Type: GrantFiled: March 15, 2002Date of Patent: June 12, 2007Assignee: The Daily Wellness CompanyInventors: Hank C. K. Wuh, Aileen S. Trant
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Patent number: 7226916Abstract: The present invention relates to a preparation suitable for the prevention and/or treatment of vascular disorders, comprising the following fractions: fraction a) consisting of long chain polyunsaturated fatty acids; fraction b) consisting of phospholipids, which fraction contains at least two different phospholipids selected from the group consisting of phosphatidylserine, phosphatidylinositol, phosphatidylcholine and phosphatidylethanolamine. fraction c) consisting of compounds which are a factor in methionine metabolism, which fraction contains at least one member selected from the group consisting of folic acid, vitamin B12, vitamin B6, magnesium and zinc.Type: GrantFiled: November 2, 2000Date of Patent: June 5, 2007Assignee: N.V. NutriciaInventors: Amanda Johanne Kiliaan, Robert Johan Joseph Hageman
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Patent number: 7208180Abstract: The present invention relates to a method for the prevention and/or treatment of vascular disorders and/or secondary disorders associated therewith, such as depression. The method according to the invention comprises the oral administration of a preparation which contains at least the following fractions: a) long chain polyunsaturated fatty acids; b) at least two different phospholipids selected from the group consisting of phosphatidylserine, phosphatidylinositol, phosphatidylcholine and phosphatidylethanolamine and c) one or more compounds which are a factor in methionine metabolism, which compounds are selected from the group consisting of folate, vitamin B12, vitamin B6, magnesium and zinc or equivalents thereof. The invention also relates to a preparation for oral dosage comprising: at least 120 mg of long chain polyunsaturated fatty acids; at least 200 mg phospholipids; at least 200 ?g folate; and at least 0.1 mg hypericin and/or at least 100 mg extract of Withania somnifera.Type: GrantFiled: July 9, 2001Date of Patent: April 24, 2007Assignee: N.V. NutriciaInventors: Amanda Johanne Kiliaan, Robert Johan Joseph Hageman
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Patent number: 7195787Abstract: Topical cosmetic compositions for application to the skin comprises a suitable diluent or carrier in combination with a synergistic mixture of three anti-free-radical agents selected from ascorbic acid, its salts, esters, glucosides and glucosamines; tocopherol and its esters; herbal extracts selected from gingko biloba, morus alba, origanum vulgare, panax ginseng, rosmarinus officinalis, birch extract, camellia sinensis, acerola cherry powder and grape seed oil.Type: GrantFiled: September 7, 2000Date of Patent: March 27, 2007Assignee: The Boots Company PLCInventors: Melanie Ann Pykett, Ailsa Helen Craig, Edward Galley, Christopher Smith, Stewart Paul Long
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Patent number: 7186424Abstract: The present invention is a multifunctional nutrient supplement and a process for creating the supplement. The supplement comprises a mixture of lecithin, ginkgo biloba and wheat germ oil. The supplement is made with a five step formation process. The first step of the process uses CO2 supercritical extraction to remove cholesterol, glyceride and fatty acids from an egg yolk. Wheat germ oil is then obtained from dried wheat germ using CO2 supercritical extraction. Gingko biloba is then removed from ginkgo leaves using CO2 supercritical extraction. The egg yolk/lecithin from the first extraction is then combined with the wheat germ oil from the second extraction. Ethanol is then added to the mixture of lecithin and wheat germ oil and low temperature vacuum distilled to create a lecithin and wheat germ oil mixture. The ginkgo biloba extract is then added to the lecithin/wheat germ oil mixture to create the nutrient supplement.Type: GrantFiled: September 23, 2004Date of Patent: March 6, 2007Inventors: Ming Xie, Dingzhong Xie, Yong Feng, Hui Zeng
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Patent number: 7138148Abstract: The invention concerns the use of Ginkgo biloba extracts, and in particular Ginkgo biloba extracts comprising 20 to 30% of flavoneglycosides, 2.5 to 4.5% in total of gingkolides A, B, C and J, 2 to 4% of bilobalide, less than 10% of proanthocyanidins and at least 10 ppm of alkylphenol type compounds, for preparing a medicine for treating sarcopenia.Type: GrantFiled: July 16, 2002Date of Patent: November 21, 2006Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (SCRAS)Inventor: Yves Christen
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Patent number: 7128932Abstract: Disclosed are pharmaceutical compositions containing: extracts of Tribulus terrestris, Turnera diffusa and Cinnamon cassia in the weight ratio of 1.5–3.5:1–2:0.1–0.4 respectively; Ginkgo biloba extract, and optionally arginine or a physiologically equivalent esters salts or precursor thereof. The compositions according to the invention are useful in the treatment of male and female sexual dysfunctions.Type: GrantFiled: April 30, 2003Date of Patent: October 31, 2006Assignee: Indena S.p.A.Inventors: Ezio Bombardelli, Paolo Morazzoni, Antonella Riva, Roberto Seghizzi
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Patent number: 7112343Abstract: The present invention discloses an all natural composition comprising herbs for the use of restoring the immune system and subsequent medicinal value. The formulization of the present invention utilizes the benefits of herbal medicine for the use of restoring the immune system to protect and cure the body from infectious disease and various allergies. The composition formula consists of nineteen herbal ingredients in powder form that carrot powder, pau d' arco bark, gingko leaf, myrrh bark, echinacea augusta folia, slippery elm bark, heal-all-herb, celery stalk, celery leaf, red clover blooms, burdock root, goldenseal root, poke root, garlic bulb powder, beet root powder, yellow dock root, dandelion root, St. John's wort, and capscium in predetermined quantities.Type: GrantFiled: May 24, 2004Date of Patent: September 26, 2006Inventor: Robbie Shoemake
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Patent number: 7048954Abstract: A process for the preparation of an extract of Ginkgo biloba leaves, comprising i. extraction of the dried fragments of Ginkgo biloba leaves in ethanol containing a maximum of 20% by weight of water; ii. concentration of the extract under reduced pressure in the presence of an aqueous solution of sodium chloride and elimination of the dark oil from the remainder of the clear solution; iii. washing of the residual aqueous solution by liquid-liquid extraction with n-hexane, n-heptane or cyclohexane, iv. liquid-liquid extraction of the aqueous phase washed with ethyl acetate; and v. washing of the ethyl acetate phase obtained in stage iv with a sodium chloride solution followed by evaporation to dryness of the washed ethyl acetate phase and use of the resulting extract to treat cerebral and peripheral vascular disorders and neurodegenerative diseases.Type: GrantFiled: April 9, 2002Date of Patent: May 23, 2006Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)Inventor: Beng Poon Teng
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Patent number: 7037533Abstract: The present invention related to a functional agent for decomposing nicotine and a method of preparing the same. The agent includes natural plant extracts such as green tea leaves, mulberry leaves, ginkgo nuts, celery, lemon, apple, dried orange peel, and licorice root. The functional agent of the present invention facilitates the decomposition of nicotine and inhibits the generation of carcinogen. In addition, the functional agent shows an anti-oxidant effect, inhibits mutation and remarkably reduces the generation rate of lung cancer.Type: GrantFiled: February 21, 2002Date of Patent: May 2, 2006Assignees: Regen Biotech, Inc.Inventors: Jong-Moon Jung, Ji-Hoon Kim, Eun-Ju Kim, Myoung-Gyu Park
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Patent number: 6964969Abstract: A nutritional supplement composition for normalizing impaired or deteriorating neurological function in humans is composed of: at least one agent which promotes synthesis of ATP and/or creatine phosphate in the body, at least one antioxidant for scavenging free radicals in at least one pathway in the body; at least one agent for normalizing or maintaining membrane function and structure in the body; at least one agent for normalizing or maintaining normal neurotransmitter function in the body; at least one agent for down-regulating cortisol action; and at least one agent for suppressing activation of apoptotic pathways in the body.Type: GrantFiled: April 19, 2001Date of Patent: November 15, 2005Inventor: Edward Larry McCleary
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Patent number: 6958163Abstract: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.Type: GrantFiled: June 27, 2002Date of Patent: October 25, 2005Assignee: Color Access, Inc.Inventors: Vasile Ionita-Manzatu, Mirela Ionita-Manzatu, Gheorghe Cioca, Andrew J. Bevacqua
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Patent number: 6936283Abstract: A stable composition preferably a refreshing drink for accelerating degradation of alcohol and acetaldehyde in the body, comprises synergistic combination of caffeine, herbs and fructose. Preferably, the composition comprises, Caffeine, Guaranà caffeine, Yerba Matè, Eleutherococcus senticous, Panax ginseng, ginger, Glycyrrhiza glabra (Liquorice Root), fructose and additional ingredients (sugars, flavourings, colourings, vitamins, stabilisers, whole fruit powder and the like), and optionally ginkgo biloba.Type: GrantFiled: July 25, 2003Date of Patent: August 30, 2005Inventor: Bjørn T. Langeland
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Patent number: 6936285Abstract: The invention relates to the use of Ginkgo biloba extracts for preparing a medicament intended to ease the withdrawal of individuals dependent on the consumption of a substance engendering dependency and/or addiction, such as in particular alcohol, amphetamines, tobacco, drugs inducing toxicomania.Type: GrantFiled: December 1, 1998Date of Patent: August 30, 2005Assignee: Societe de Conseils de Recherches d'Application Scientifiques (S.C.R.A.S.Inventor: Katy Drieu
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Patent number: 6818208Abstract: A cosmetic composition containing a flavonoid extract of ginko biloba leaves comprising 28 to 35% by weight of flavonoid glycosides and a maximum of 1% by weight of terpenes.Type: GrantFiled: September 17, 2002Date of Patent: November 16, 2004Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)Inventor: Joseph O'Reilly
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Patent number: 6818233Abstract: The invention provides a dietary supplement comprising at least one flavonoid source and an enzyme, that is effective for inhibiting in vivo platelet activity and LDL cholesterol oxidation in a mammal at a dosage of about 30 mg/Kg or less. The supplement may contain flavonoid sources found in grape seed extracts, grape skin extracts, bilberry extracts, ginkgo biloba extracts or the flavonoid quercetin. The supplement may also contain fungal proteases, acid stable proteases and bromelain. The invention further provides a method for using the dietary supplement and an article of manufacture containing the supplement.Type: GrantFiled: November 20, 1998Date of Patent: November 16, 2004Assignee: Melaleuca, Inc.Inventor: Lynn Perkes
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Patent number: 6814985Abstract: The present invention relates generally to a composition for the treatment or prophylaxis of allergic and inflammatory reactions such as but not limited to Type I hypersensitivity reactions in mammals. More particularly, the present invention is directed to compositions comprising herbs or extracts of herbs or botanical or horticultural equivalents of the herbs or chemical or functional equivalents of the herbal extracts useful in the treatment or prophylaxis of allergic and inflammatory reactions such as but not limited to respiratory disorders. The present invention further contemplates a method of treating allergic and inflammatory reactions in mammals and in particular Type I hypersensitivity disorders and even more particularly respiratory disorders by the administration of a herbal composition or its chemical or functional equivalent.Type: GrantFiled: September 28, 2001Date of Patent: November 9, 2004Assignee: G & W Aust Pty. Ltd.Inventor: Guorang Hu
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Publication number: 20040185118Abstract: An innovative health food for good sleepy is provided for improving the factors that interfere with sleep as much as possible and is suitable for attaining good sleep and deep sleep mainly comprising herbal medicines in combination. The health food for good sleep contains a Panax ginseng extract, a Ginkgo biloba leaf extract, a Ganoderma lucidum extract, and calcium, which are mixed together in predetermined proportions. For example, the mixture contains 0.5 to 1.0 parts by weight of the Ginkgo biloba leaf extract, 0.1 to 0.5 parts by weight of the Ganoderma lucidum extract, and 0.1 to 1.0 parts by weight of calcium with respect to 1 part by weight of the Panax ginseng extract.Type: ApplicationFiled: March 19, 2003Publication date: September 23, 2004Inventors: Katsumichi Matsushige, Ryuichi Moriya, Nobuki Muramatsu
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Publication number: 20040180105Abstract: The invention relates to the use of Ginkgo biloba extracts for preparing a medicament intended to ease the withdrawal of individuals dependent on the consumption of a substance engendering dependency and/or addiction, such as in particular alcohol, amphetamines, tobacco, drugs inducing toxicomania.Type: ApplicationFiled: March 25, 2004Publication date: September 16, 2004Applicant: SOCIETE DE CONSEILS DE RECHERCHES D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)Inventor: Katy Drieu
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Publication number: 20040166180Abstract: The invention concerns the use of Ginkgo biloba extracts, and in particular Ginkgo biloba extracts comprising 20 to 30% of flavoneglycosides, 2.5 to 4.5% in total of gingkolides A, B, C and J, 2 to 4% of bilobalide, less than 10% of proanthocyanidins and at least 10 ppm of alkylphenol type compounds, for preparing a medicine for treating sarcopenia.Type: ApplicationFiled: December 22, 2003Publication date: August 26, 2004Inventor: Yves Christen
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Patent number: 6773729Abstract: A dietary supplement consisting essentially of a combination of Ginseng and Ginkgo to improve the speed of memory and memory quality in normal, healthy subjects and to prevent deterioration of the speed of memory in people with decreased cognitive functions, and to counteract cognitive fatigue.Type: GrantFiled: November 1, 2002Date of Patent: August 10, 2004Assignee: Pharmaton S.A.Inventors: Orlando Petrini, Andrew Scholey
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Pharmaceutical and/or cosmetic compositions for the treatment of localised adiposities and cellulite
Publication number: 20040151786Abstract: The present invention relates to pharmaceutical and/or cosmetic compositions containing a combination of the following active principles: a) complex of escin/beta-sitosterol with phospholipids, b) complex of Gingko biloba dimeric flavonoids with phospholipids, c) complex of Centella asiatica triterpenes with phospholipids, and optionally one or both of: d) ethyl ximeninate e) Coleus forskolii standardized extract.Type: ApplicationFiled: November 18, 2003Publication date: August 5, 2004Inventor: Francesco Di Pierro -
Patent number: 6759065Abstract: A compound is extracted from vegetable material, wherein the vegetable material is reduced and treated with a solvent. According to the invention, the vegetable material is frozen using a liquid nitrogen and in frozen condition reduced in size. According to two important embodiments, the vegetable material comes from the ginkgo tree, in particular fresh leaves, and water is used as a solvent. The invention also relates to a pharmaceutical preparation and a cosmetic preparation comprising as active component a compound obtained by the method according to the invention.Type: GrantFiled: February 15, 2001Date of Patent: July 6, 2004Assignee: XenoBiosisInventor: Henri M. Ruijten
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Patent number: 6756065Abstract: A preparation based on plant extracts, with an antioxidant action which is particularly useful in the treatment of circulation and chronic degenerative problems and in the treatment of hypertension, characterized in that its active ingredients comprise Ginkgo biloba biflavones, catechin and/or epicatechin, cumarin and derivatives thereof and a component selected from among madecassic acid, asiatic acid, asiaticoside or combinations thereof.Type: GrantFiled: June 4, 2002Date of Patent: June 29, 2004Assignees: Ceteris Holding B.V., Amsterdam (Olanda) Succursale Di LuganoInventor: Gianfranco Merizzi
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Publication number: 20040109907Abstract: The invention concerns a method for preparing an extract of Ginkgo biloba leaves, comprising the following successive steps: i) extracting dry fragments of Ginkgo biloba leaves in ethanol containing at least 20 wt. % of water; ii) concentrating the extract under reduced pressure in the presence of at least an aqueous sodium chloride solution and eliminating the dark oil from the rest of the clear solution; iii) washing the residual aqueous solution by liquid-liquid extraction with n-hexane n-heptane or cyclohexane; iv) liquid-liquid extraction of the washed aqueous phase with ethyl acetate; v) washing the ethyl acetate phase obtained at step iv) with a sodium chloride solution then evaporating by dry process the washed ethyl acetate phase.Type: ApplicationFiled: September 17, 2003Publication date: June 10, 2004Inventor: Beng Poon Teng
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Publication number: 20040101578Abstract: The present invention relates to a composition containing ginkgo biloba extract that inhibit angiogenesis and matrix metalloproteinases. The ginkgo biloba extract of the present invention suppress angiogenesis and activity of matrix metalloproteinases, so that it can be applied to medicine for disease related in angiogenesis and matrix metalloproteinases.Type: ApplicationFiled: February 4, 2003Publication date: May 27, 2004Inventors: Min-Young Kim, Byung-Young Park, Chang-Hee Moon, Eun-Kyu Park
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Publication number: 20040096526Abstract: The present invention related to a functional agent for decomposing nicotine and a method of preparing the same. The agent includes natural plant extracts such as green tea leaves, mulberry leaves, ginkgo nuts, celery, lemon, apple, dried orange peel, and licorice root. The functional agent of the present invention facilitates the decomposition of nicotine and inhibits the generation of carcinogen. In addition, the functional agent shows an anti-oxidant effect, inhibits mutation and remarkably reduces the generation rate of lung cancer.Type: ApplicationFiled: August 18, 2003Publication date: May 20, 2004Inventors: Jong-Moon Jung, Ji-Hoon Kim, Eun-Ju Kim, Myoung-Gyu Park
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Publication number: 20040096420Abstract: Disclosed herein are novel compositions and/or formulations containing minoxidil as an active ingredient in combination with other active agents and/or enhancer agents (e.g., saw palmetto extract and nettle root extract) which increase the hair growth capability of the composition. Also disclosed are methods of using the novel compositions to treat male patterned baldness and to stimulate hair growth on the scalp, including both the apex and frontal regions of the scalp.Type: ApplicationFiled: July 21, 2003Publication date: May 20, 2004Inventors: Chris Catalfo, Fred Mussari
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Publication number: 20040091477Abstract: The invention features a composition containing an immunophilin-binding compound and a ginkgolide compound, methods of inducing immunosuppression, and methods of screening for immunosuppressive ginkgolide compounds. The ginkgolide compound is selected from the group consisting of a phosphodiesterase inhibitor, a platelet activating factor (PAFR) antagonist, and a free radical scavenger.Type: ApplicationFiled: June 5, 2003Publication date: May 13, 2004Inventors: David Haines, Arpad Tosaki, Fadia F. Mahmound
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Patent number: 6733797Abstract: The present invention relates to a neurochemical formulation comprising a supplement for improving function of neurons, improving memory and cognitive abilities, and reversing free radical damage caused by aging or neurodegenerative disease. The formulation comprises phosphoesters and antioxidants. Components may have antioxidant properties or enhance properties of other components. The synergistic combinations allow individual component dosages to be reduced, thereby minimizing potential toxicity.Type: GrantFiled: November 15, 2001Date of Patent: May 11, 2004Inventor: William K. Summers
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Publication number: 20040043054Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca.Type: ApplicationFiled: August 27, 2002Publication date: March 4, 2004Inventors: William Shell, Elizabeth Charuvastra
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Publication number: 20040028756Abstract: Antagonists to platelet-activating factor provide analgesic effects as well as limit the release of inflammatory mediators. Use of these antagonists in the form of pharmaceutical compositions or nutritionals is beneficial (1) in the treatment of acute and/or chronic pain; (2) in the inhibition of inappropriate or excessive contraction of the uterus; (3) in the treatment of septic shock; and (4) in the inhibition of angiogenesis and/or tumor cell proliferation.Type: ApplicationFiled: March 27, 2003Publication date: February 12, 2004Inventors: Lisa A. Teather, Richard J. Wurtman, Jane E. Magnusson
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Publication number: 20040028757Abstract: The invention relates to a composition intended for administration by the oral or topical route and comprising, in a physiologically acceptable medium, DHEA and/or a chemical or biological precursor or derivative of the latter, in combination with at least one NO-synthase inhibitor.Type: ApplicationFiled: June 23, 2003Publication date: February 12, 2004Inventors: Marie-Madeleine Cals-Grierson, Roland Roguet, Guy Courchay
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Publication number: 20040022879Abstract: A composition including (a) a Platelet Activating Factor (PAF) Inhibitor and (b) an antioxidant which interferes with the arachidonic acid cascade and also has antioxidant activity. The compositions are useful for the treatment or the relief of inflammatory disease, thrombosis, cardiac problems, and/or conditions caused by platelet induced blood clotting.Type: ApplicationFiled: August 1, 2003Publication date: February 5, 2004Inventor: Nicholas J. Larkins
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Publication number: 20040009244Abstract: The present invention relates to a composition comprising Melissa leaf extract that inhibits angiogenesis and matrix metalloproteinase activity. The Melissa leaf extract of the present invention inhibits angiogenesis and activity of matrix metalloproteinase, so that it can be applied to treat or prevent diseases related to angiogenesis and matrix metalloproteinase. The composition of the present invention comprising Melissa leaf extract may also comprise more than one component of the other anti-angiogenic, anti-cancer, anti-inflammatory and anti-aging components. This particular composition comprising Melissa leaf extract can be used for pharmaceutical, dietetic and/or cosmetic purposes.Type: ApplicationFiled: June 12, 2003Publication date: January 15, 2004Inventors: Min-Young Kim, Byung-Young Park, Chang-Hee Moon, Eun-Kyu Park, Kyoung-Mi Kim
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Patent number: 6676977Abstract: Compositions and methods for reducing or eliminating the appearance of cellulite. The method involves administering to a patient in need of treatment therapeutically effective amounts of a sugar compound that is converted to a glycosaminoglycan in the patient in an amount sufficient to thicken the skin, a primary antioxidant component in an amount sufficient to substantially inhibit the formation of collagenase and elastase, at least one amino acid component in an amount sufficient to assist in the thickening of the skin, and at least one transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin so as to reduce or eliminate the appearance of cellulite. A preferred method of treatment further includes administering the components above in conjunction with a vascular dilator to improve blood supply to the skin and/or a fat burner to reduce absorption or digestion of fat in the digestive tract or to prevent the production of fat.Type: GrantFiled: January 22, 2002Date of Patent: January 13, 2004Inventor: Howard Murad
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Publication number: 20040002423Abstract: The present invention provides a composition for enhancing growth factor production, comprising a plant-derived enhancer for growth factor production; a therapeutic agent or prophylactic agent for a disease requiring enhancement of growth factor production and a food, beverage or feed for enhancing growth factor production, each comprising the above composition. In addition, the present invention relates to a functional food, beverage or feed excellent in health enhancement.Type: ApplicationFiled: October 10, 2002Publication date: January 1, 2004Inventors: Hiromu Ohnogi, Masahiro Shiraga, Tuo-Ping Li, Eiji Kobayashi, Kaori Nishimura, Hiroaki Sagawa, Ikunoshin Kato
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Publication number: 20030232098Abstract: Therapeutic compositions for the treatment of tinnitus are described which contain effective amounts of Ginkgo biloba, garlic and zinc. In formulations containing greater than 50 mg of zinc, the composition may further contain copper. Methods of treating patients having tinnitus include prescribing effective daily doses of the therapeutic compositions of the present invention over a sixty to ninety day period to maximize improvement in the condition, followed by a daily regimen of the therapeutic compositions.Type: ApplicationFiled: June 11, 2003Publication date: December 18, 2003Inventor: Barry Keate
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Patent number: 6649195Abstract: A powerful formulation for preventing and treating macular degeneration, cataracts, glaucoma and other eye diseases, and contains over thirty naturally effective vitamins, minerals, phytonutrients and amino acids, which have all been found to demonstrate a powerful protective effect on the health of the eye.Type: GrantFiled: July 11, 2002Date of Patent: November 18, 2003Assignee: Vitacost.com, Inc.Inventor: Wayne F. Gorsek
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Publication number: 20030211456Abstract: The present invention is directed to a method of establishing an “identity” of Ginkgo biloba leaves or isolated ginkgolide B (GKB) or another component of the extract of Ginkgo biloba leaves, by obtaining a “gene regulation profile”. The invention is also directed to a method of verifying the identity of a Ginkgo biloba extract by comparing the gene regulation profile of a Gingko biloba extract of unknown or questionable origin with the gene regulation pofile of a Gingko biloba extract of known origin. The present invention is further directed to a method of establishing a gene expression profile of Ginkgolide A, Ginkgolide B or any other component isolated from a Ginkgo biloba extract, more particularly, from EGB 761®.Type: ApplicationFiled: March 11, 2003Publication date: November 13, 2003Inventors: Vassilios Papadopoulos, Katy Drieu
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Publication number: 20030203053Abstract: The invention provides methods and compositions for maintaining a state of wellness in a human by providing a dietary supplement comprising L-arginine, alone or in combination with ginseng and ginkgo biloba and/or additional nutritional supplements. The invention provides a unique blend of components that, in combination, synergistically bestow sexual wellness upon a human when taken regularly as a dietary supplement.Type: ApplicationFiled: April 7, 2003Publication date: October 30, 2003Inventors: Hank C.K. Wuh, Aileen S. Trant
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Publication number: 20030195186Abstract: Many males and females experience sexual dysfunction either caused or made worse by medications, other substances, diseases, and other medical conditions. Currently, there is need for additional treatment alternatives for these patients' sexual dysfunction. The subject invention provides a novel treatment for these individuals with sexual dysfunction by inhibiting the enzyme that breaks down acetylcholine (a compound that helps modulate normal sexual function) and elevates acetylcholine levels in the body.Type: ApplicationFiled: April 10, 2003Publication date: October 16, 2003Applicant: University of FloridaInventor: Nathan Andrew Shapira
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Patent number: 6632460Abstract: This invention provides different compositions extracted from Ginkgo biloba leaves. Said compositions comprise new active components. This invention also provides a method of preparation of the compositions and individual components of said compositions. Finally, this invention provides various uses of this composition.Type: GrantFiled: October 10, 2002Date of Patent: October 14, 2003Assignee: Shanghai Xingling Sci. & Tech. Pharmaceutical Co., Ltd.Inventors: De Long Xie, Ning Wang, Qi Gao, Guo An Zhang, Bao Ping Shao, Xiao Wu Jin, Xin Sheng Huang
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Publication number: 20030170325Abstract: Compositions in gel form or suppository are provided for treatment of vaginal dryness, wherein the composition comprises certain herbal compounds, with or without a vitamin such as, for example, vitamin A, C, D or E. The compositions may include an anti-bacterial agent and are applied to the affected area in an amount which is effective to provide the required relief when applied over a period of time.Type: ApplicationFiled: January 4, 2002Publication date: September 11, 2003Inventors: Harold Mermelstein, Frank P. Marchese
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Publication number: 20030170328Abstract: The invention features compositions containing an antioxidant and/or a gingkolide compound to reduce inflammation. Combination drug therapy using antioxidant and/or a gingkolide compound with an anti-inflammatory agent reduces adverse side effects associated with many known anti-inflammatory agents.Type: ApplicationFiled: January 16, 2003Publication date: September 11, 2003Inventors: David Haines, Fadia F. Mahmoud