Containing Or Obtained From Allium (e.g., Onion, Garlic, Ramp, Chive, Scallion, Etc.) Patents (Class 424/754)
  • Patent number: 10265342
    Abstract: A sustained-release composition is provided in the present disclosure for producing a therapeutic gas, such as hydrogen sulfide or hydrogen. The sustained-release composition includes a precursor and a carrier. The precursor is diallyl trisulfide or magnesium, and the carrier includes a poly lactic-co-glycolic acid copolymer for carrying the precursor with an efficient amount.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: April 23, 2019
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Hsing-Wen Sung, Chieh-Cheng Huang, Wei-Lin Wan, Meng-Hsuan Hsieh, Po-Chien Shih, Hsin-Yi Hu
  • Patent number: 10238616
    Abstract: An immunomodulator useful for modulating immune function and maintaining intravital homeostasis is provided. The immunomodulator comprises S-1-propenycysteine or a salt thereof as an active ingredient.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: March 26, 2019
    Assignee: WAKUNAGA PHARMACEUTICAL CO., LTD.
    Inventors: Junichiro Suzuki, Yukihiro Kodera, Kenji Itoh, Toshiaki Matsutomo
  • Patent number: 9902685
    Abstract: The present invention relates to a method for reducing the production of methane emanating from the digestive activities of a ruminant and/or for improving ruminant animal performance by using, as active compound at least one organic molecule substituted at any position with at least one nitrooxy group, or a salt thereof, which is administrated to the animal together with the feed. The invention also relates to the use of these compounds in feed and feed additives such as premix, concentrates and total mixed ration (TMR) or in the form of a bolus.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: February 27, 2018
    Assignee: DSM IP ASSETS B.V.
    Inventors: Stephane Duval, Maik Kindermann
  • Patent number: 9636360
    Abstract: An orally administered composition that includes least one alkaline agent with a pH of at least 9.0 to 12.0, mixed in an aqueous vehicle with relatively high surface tension, high viscosity and lateral adhesion properties. When mixed, a low water soluble emulsion is formed that evenly coats and partially adheres to the lower section of the esophagus and the LES and forms a relatively long acting, protective barrier and partially neutralizes gastric acid. In one embodiment, the alkaline agent is potassium hydroxide and the aqueous vehicle is made of hydroxypropyl methyl cellulose, polyethylene glycol or ethylene glycol and additional thickener agents capable of withstanding high pH environments, such as xanthan gum, croscarmellose sodium, and microcrystalline cellulose. Additional organoleptic agents, such as gum Arabic and polyethylene glycol, flavorings, such as sodium chloride, acesulfame potassium, sodium saccharine, and mint, and stabilizers such as colloidal silica made be added.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: May 2, 2017
    Inventors: Ismail Gurol, Robert Burns, Steven Loyd
  • Patent number: 9226906
    Abstract: The present invention relates to a method and nutritional supplement which stimulates appetite and slows metabolism of a mammal, thereby enhancing weight gain for the mammal. The method of enhancing weight gain of the mammal comprises administering to the mammal an effective amount of at least two types of alkamide or isobutylamide compound extracted from Echinacea species along with an antioxidant and optionally minerals. The nutritional supplement of the present invention comprises an antioxidant and at least two types of alkamide or isobutylamide compounds derived from Echinacea species. Minerals such as zinc and magnesium can also be added to the nutritional supplement to provide even better effect.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: January 5, 2016
    Assignee: Supragenix, LLC
    Inventors: Travis Kurt Alvord, Tyler Stevens Alvord
  • Publication number: 20150139938
    Abstract: The present invention provides methods of promoting arteriogenesis in a subject. Embodiments include methods comprising: administering an effective dose of tocotrienol to the subject; causing an increase in Tissue Inhibitor of Metalloproteinase Metallopeptidase Inhibitor 1 (TIMP1) in vessels of cerebrovascular collateral circulation in the subject; attenuating the activity of Matrix Metalloproteinase-2 (MMP2); thereby promoting arteriogenesis.
    Type: Application
    Filed: June 7, 2013
    Publication date: May 21, 2015
    Applicant: Ohio State Innovation Foundation
    Inventors: Chandan Sen, Cameron Rink, Sashwati Roy, Greg Christoforidis
  • Publication number: 20150056259
    Abstract: Nanoengineered particulate coatings (NPCs) comprise a multiplicity of particulate hosts that are infused with a nanophase comprising a surfactant and at least one guest. The particulate hosts can be clay particles, the surfactant can be a cationic surfactant, and the guest can be an insect repellant. For example, montmorillonite particles infused with hexadecyl trimethyl ammonium bromide and garlic oil form NPCs that may be used to form an emulsion or suspension for spraying on citrus trees to repel Asian Citrus Psyllid.
    Type: Application
    Filed: February 14, 2013
    Publication date: February 26, 2015
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Parvesh Sharma, Aarthi Narayanan, Hassan E. El-Shall, Brij M. Moudgil
  • Publication number: 20150044312
    Abstract: The invention relates to a composition comprising a composition of an extract derived from Allium Porum L. genus plant, in vegetable oil and Neem oil.
    Type: Application
    Filed: March 8, 2013
    Publication date: February 12, 2015
    Inventor: Sergio Casella
  • Patent number: 8945597
    Abstract: The invention generally relates to environmental friendly pesticide compounds, formulations, methods of preparation and application and utilities thereof. More particularly, the invention relates to pesticide compounds and formulations that include terpenes or terpenoids having chemical formula of (C5H8)n, and its derivatives and analogs thereof, as active insecticidal ingredients; certain botanical essential oils as synergists, and other select ingredients as additives.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: February 3, 2015
    Inventor: Tao Zhong
  • Patent number: 8945636
    Abstract: A stabilized formulation for skin care, wound care and/or other tissue healing applications and methods for making the same is described. The stabilized formulation stabilizes omega-3 polyunsaturated fatty acids and is constituted of the omega-3 polyunsaturated fatty acids in combination with tocopherol (Vitamin E), ascorbic acid (Vitamin C), herb extract, and a fat-soluble antioxidant. Methods for making and using the stabilized formulation are also described.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: February 3, 2015
    Assignee: Kerecis EHF
    Inventors: Gudmundur Fertram Sigurjonsson, Biljana Ilievska, Baldur Tumi Baldursson
  • Patent number: 8883229
    Abstract: The present invention relates to a botanical repellent composition intended for pest insect control. In some embodiments, the composition may contain about 75% to about 92% garlic extract (Allium sativum) and about 8% to about 25% humic acids and diluents.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: November 11, 2014
    Inventor: José Luis Miranda Valencia
  • Publication number: 20140322367
    Abstract: Various human diseases, including herpes, antibiotic resistant bacterial infections, cutaneous Leishmaniasis, malaria and multiple sclerosis can be treated with injections of garlic juice. The garlic juice is produced by cutting, crushing, or otherwise damaging garlic cloves, and collecting the juice. This garlic juice is dissolved in a carrier solution, such as water or saline, and then injected into the patient.
    Type: Application
    Filed: July 11, 2014
    Publication date: October 30, 2014
    Inventor: Behnam Azizkhani
  • Publication number: 20140322366
    Abstract: A coniferyl alcohol or a Compositae family, Brassicaceae family, Umbelliferae family, Lamiaceae family, Liliaceae family or Amaranthaceae plant extract provides various uses associated with hTRPA1 activation, and, being a natural compound, involves relatively few side effects in the body and has substantial industrial applicability. The coniferyl alcohol or the Compositae family, Brassicaceae family, Umbelliferae family, Lamiaceae family, Liliaceae family or Amaranthaceae plant extract of the present invention not only will be a novel medical or food raw material which is helpful in maintaining homeostasis in the body associated with hTRPA1 activation, but can also be used to advantage in hTRPA1 antagonist screening.
    Type: Application
    Filed: November 9, 2012
    Publication date: October 30, 2014
    Applicant: KOREA FOOD RESEARCH INSTITUTE
    Inventors: Mee Ra Rhyu, Hee Jin Son, Yi Seul Kim, Seo Hyeon Song, Min Jung Kim, Myung Ji Jung, Hye Jin Lee, Hye Young Kim, Jae-Ho Park
  • Patent number: 8859018
    Abstract: The present invention relates to a use of an emulsion comprising an antimicrobial essential oil, acacia gum and water for improving the antimicrobial effect of the essential oil in an aqueous composition, particularly in a food or beverage composition. Further, the invention relates to a process to improve the antimicrobial effect of an essential oil, and aqueous compositions comprising an emulsion of an antimicrobial essential oil, acacia gum and water.
    Type: Grant
    Filed: November 24, 2011
    Date of Patent: October 14, 2014
    Assignee: Nestec S.A.
    Inventors: Cecile Gehin-Delval, Corinne Appolonia Nouzille, Seow Leng Ng
  • Publication number: 20140248332
    Abstract: The present invention relates to a composition comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes. Furthermore the present invention relates to a method for preparing a composition comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes. Further, the present invention relates to a composition comprising an onion extract (A) (Allium cepa) and liposomes, obtainable by or obtained by said method. Furthermore, the present invention relates to compositions comprising a first onion extract (A), and liposomes, wherein at least a portion of the onion extract is encapsulated in the liposomes, for use in treating and/or preventing scars.
    Type: Application
    Filed: June 21, 2012
    Publication date: September 4, 2014
    Applicant: MERZ PHARMA GmbH & CO. KGaA
    Inventors: Peter Boderke, Martina Heberer, Petra Scheppler
  • Publication number: 20140242199
    Abstract: Compositions useful for controlling pests are disclosed. In some embodiments, the composition includes a pesticidal natural oil and a polar aromatic solvent. Methods of making and using the compositions are disclosed.
    Type: Application
    Filed: October 4, 2012
    Publication date: August 28, 2014
    Inventors: Karan Manhas, Annett Rozek
  • Patent number: 8808762
    Abstract: The present invention relates to agricultural emulsion concentrates which form stable oil-in-water emulsions when diluted with water. More specifically, the invention relates to stable oil-in-water emulsions which include cinnamaldehyde and diallyl disulfide with a Calsogen® EH and Surfonic® CO 36 emulsion system. The increased stability of the emulsion allows for efficient mixing of the emulsion ingredients and effective storage and application of the cinnamaldehyde and diallyl disulfide to areas in need of nematode protection or treatment.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: August 19, 2014
    Assignee: Valent BioSciences Corporation
    Inventors: Benjamin A. Belkind, Bassam Shammo, Rebecca Dickenson, Linda A. Rehberger, Daniel F. Heiman
  • Patent number: 8808767
    Abstract: A composition for the control of nematodes consisting of salicylaldehyde and a surfactant. Garlic extract added to the salicylaldehyde provides a composition that demonstrates a more potent control action against potato cyst nematodes.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: August 19, 2014
    Assignee: Omex International Ltd.
    Inventors: Gidon Bahiri, Ian Elliott
  • Publication number: 20140227198
    Abstract: Shelf stable compositions comprising olive extracts are described herein. The compositions include an olive extract comprising hydroxytyrosol, tyrosol, and oleuropein, wherein the weight ratio of hydroxytyrosol to oleuropein is 3:1 or less and the weight ratio of hydroxytyrosol to tyrosol is 2.85:1 or less. The compositions are stable for at least 12 months. Methods of using the shelf stable compositions are also described herein.
    Type: Application
    Filed: February 10, 2014
    Publication date: August 14, 2014
    Applicant: GRADS Holdings LLLP
    Inventor: John Alkire
  • Publication number: 20140220164
    Abstract: Compositions useful for controlling pests are disclosed. In some embodiments, the composition includes a pesticidal natural oil and a polar aromatic solvent or an alkyl alcohol solvent. Methods of making and using the compositions are disclosed.
    Type: Application
    Filed: April 8, 2014
    Publication date: August 7, 2014
    Applicant: 0903608 B.C. Ltd.
    Inventors: Karan MANHAS, Annett ROZEK
  • Publication number: 20140205550
    Abstract: A method of cosmetic care comprising activating capsase-14 expression in skin deficient in caspase-14 expression by applying, on at least one skin zone in need thereof, an effective amount of a plant extract selected from the group consisting of litchi, glasswort, peach, soja seed, sweet basil, cucumber, chanterelle, leek, kiwi fruit, rhubarb, grapefruit, wheat, raspberry, plum, and mixtures thereof, to activate caspase-14 expression in said skin.
    Type: Application
    Filed: January 23, 2013
    Publication date: July 24, 2014
    Inventors: Hugo A. Corstjens, Lieve Declercq, Gerry Eyckmans, Luc F.J. Van Overloop
  • Patent number: 8784871
    Abstract: The present invention relates to a method for reducing the production of methane emanating from the digestive activities of a ruminant and or for improving ruminant animal performance by using, as active compound at least one nitrooxy alkanoic acid and/or derivative thereof, which is administrated to the animal together with the feed. The invention also relates to the use of these compounds in feed and feed additives such as premix, concentrates and total mixed ration (TMR) or in the form of a bolus.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: July 22, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Stephane Duval, Maik Kindermann
  • Publication number: 20140199418
    Abstract: Herpes infections in hum an patients can be treated with injections of garlic juice. The garlic juice is produced by cutting, crushing, or otherwise damaging garlic cloves, and collecting the juice. This garlic juice is dissolved in a carrier solution, such as water or saline, and then injected into the patient.
    Type: Application
    Filed: January 11, 2013
    Publication date: July 17, 2014
    Inventor: Behnam Azizkhani
  • Patent number: 8778421
    Abstract: Herpes infections in human patients can be treated with injections of garlic juice. The garlic juice is produced by cutting, crushing, or otherwise damaging garlic cloves, and collecting the juice. This garlic juice is dissolved in a carrier solution, such as water or saline, and then injected into the patient.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: July 15, 2014
    Inventor: Behnam Azizkhani
  • Patent number: 8753695
    Abstract: A dry insect repellent includes a plurality of non-toxic natural essential oils and an amount of soybean oil, to facilitate even distribution of the active components throughout a dry carrier matrix. The dry carrier matrix facilitates storage, handling, and application of the dry insect repellent to a treatment area for the safe and effective control of mosquitoes and other pests.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: June 17, 2014
    Inventors: Lori Ann Porter, Powell Porter, Jess Storey
  • Publication number: 20140161914
    Abstract: A composition for the control of nematodes consisting of salicylaldehyde and a surfactant. Garlic extract added to the salicylaldehyde provides a composition that demonstrates a more potent control action against potato cyst nematodes.
    Type: Application
    Filed: September 4, 2013
    Publication date: June 12, 2014
    Inventors: Gidon Bahiri, Ian Elliott
  • Publication number: 20140147528
    Abstract: The present invention relates to a garlic formulation enriched with sulphur containing amino acids and a process for enriching sulphur containing amino acids in garlic. The sulphur containing amino acids includes S-allylcysteine, S-methylcysteine, and S-allylmercaptocysteine. The percentage of enriched garlic concentrate after processing is in the range of 7.5-9.5%. The garlic formulation is useful in the treatment of Diabetes Mellitus (DM) and prevention of tissue and organ damage that occurs frequently in diabetic patients.
    Type: Application
    Filed: May 31, 2013
    Publication date: May 29, 2014
    Inventor: M. A. DEEPA
  • Publication number: 20140147529
    Abstract: The present invention relates to a method for reducing the production of methane emanating from the digestive activities of a ruminant and/or for improving ruminant animal performance by using, as active compound at least one organic molecule substituted at any position with at least one nitrooxy group, or a salt thereof, which is administrated to the animal together with the feed. The invention also relates to the use of these compounds in feed and feed additives such as premix, concentrates and total mixed ration (TMR) or in the form of a bolus.
    Type: Application
    Filed: December 20, 2011
    Publication date: May 29, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Stephane Duval, Maik Kindermann
  • Publication number: 20140134282
    Abstract: The present invention relates to a method for reducing the production of methane emanating from the digestive activities of a ruminant and or for improving ruminant animal performance by using, as active compound at least one nitrooxy alkanoic acid and/or derivative thereof, which is administrated to the animal together with the feed. The invention also relates to the use of these compounds in feed and feed additives such as premix, concentrates and total mixed ration (TMR) or in the form of a bolus.
    Type: Application
    Filed: January 21, 2014
    Publication date: May 15, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Stephane DUVAL, Maik KINDERMANN
  • Publication number: 20140127179
    Abstract: A formulation of supplement is able to boost the natural cells, both increasing the population of the natural cells and enhancing the natural cell's activity. The formulation can be administered via different forms, such as tablet, injection, skin absorption and etc. This formulation comprises 16 different components, including Alpha Lipoic Acid, Arabinoxylin, Curcumin, Garlic, Genistein, Ginseng, Lentinan, Mistletoe, N-Acetylcysteine, Resveratrol, Selenium, Vitamin B Complex, Vitamin C, Vitamin D3, Vitamin E and Zinc. By virtue of enhancing the natural killer cells (NKC) in the body, the formation is helpful for the prevention and treatment of a number of different human or animal diseases, such as cancers and viral infections. In addition, certain synergistic effects have been observed between different components in the formulation, which further enhances the beneficial effect of the formulation.
    Type: Application
    Filed: November 4, 2013
    Publication date: May 8, 2014
    Applicant: SCIENTIFIC FORMULATIONS, LLC
    Inventor: Jerry Thomas THORNTHWAITE
  • Patent number: 8697149
    Abstract: The invention provides extracts and preparations based on the species Tulbaghia violacea (Harv.) (wild garlic), which elicits a significant antimicrobial, preferably antifungal activity in vitro and in vivo, even under field and glasshouse conditions. Moreover, these extracts deriving from the soil parts as well as of the aerial parts of the plant elicit a significant bio-stimulatory activity, expressed, above all, by an increased growth metabolism supporting seed growth. Furthermore, combined extracts or preparations from Tulbaghia violacea and species of the genus Agapanthus show a higher antifungal and bio-stimulatory efficacy as compared to the extracts or preparations of the single species, indicating that synergism is participated in the involved biological processes.
    Type: Grant
    Filed: June 24, 2006
    Date of Patent: April 15, 2014
    Assignees: Agrarforum AG, Agrarforum SA (Pty) Ltd.
    Inventor: Johannes Christiaan Pretorius
  • Patent number: 8691298
    Abstract: A stabilized formulation for skin care, wound care and/or other tissue healing applications and methods for making the same is described. The stabilized formulation stabilizes omega-3 polyunsaturated fatty acids and is constituted of the omega-3 polyunsaturated fatty acids in combination with tocopherol (Vitamin E), ascorbic acid (Vitamin C), herb extract, and a fat-soluble antioxidant. Methods for making and using the stabilized formulation are also described.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: April 8, 2014
    Assignee: Kerecis EHF
    Inventors: Gudmundur Fertram Sigurjonsson, Biljana Ilievska, Baldur Tumi Baldursson
  • Patent number: 8652543
    Abstract: Compositions are disclosed containing, as active ingredients, an extract of Allium species, an extract of Citrus species and either an extract of Paullinia species and an extract of Theobroma species, or an extract of Salix species and zinc sulphate, and the method of preparation of these compositions, and cosmetic and/or pharmaceutical application of these compositions.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: February 18, 2014
    Assignee: Legacy Healthcare Holding Ltd.
    Inventors: André Ulmann, Jean-Frédéric Laville
  • Publication number: 20140044812
    Abstract: An anesthetic and therapeutic composition for use in aquaculture includes an essential oil preferably thyme oil that is mixed with ethanol in an amount of one part essential oil preferably thyme oil to five parts ethanol. The essential oil ethanol mixture is then dispersed in water preferably seawater to provide 10 to 60 ppm of essential oil. The oxygen in the composition is between about 5.00 and 6.5 mg/L and in a preferred embodiment is enhanced by an agar stabilizer. The invention also contemplates treating fish such as sheam and sobaity and shrimp and seahorse to reduce stress and maintain a temperature of about 20°-27° C.
    Type: Application
    Filed: August 7, 2012
    Publication date: February 13, 2014
    Applicant: KUWAIT INSTITUTE FOR SCIENTIFIC RESEARCH
    Inventors: Amani Al-Yaqout, Azad Ismail Saheb, Musaad Al-Roumi, Mohammed Al-Kandari
  • Publication number: 20140037577
    Abstract: The present invention includes methods and compositions for the treatment and prevention of protozoal parasitic infections utilizing Diindolylmethane-related indoles. Additive and synergistic interaction of Diindolylmethane-related indoles with other known anti-parasitic and pro-apoptotic agents is believed to permit more effective therapy and prevention of protozoal parasitic infections. The methods and compositions described provide new treatment of protozoal parasitic diseases of mammals and birds including malaria, leishmaniasis, trypanosomiasis, trichomoniasis, neosporosis and coccidiosis.
    Type: Application
    Filed: October 10, 2013
    Publication date: February 6, 2014
    Inventor: Michael A. Zeligs
  • Publication number: 20140037730
    Abstract: Compositions useful for relieving the symptoms commonly known as stomach acidity, heartburn or, more technically, esophageal reflux (GERD), that comprise a fatty acid and a plant extract. These compositions have been tried in patients with clinical records of previous diagnosis of GERD, chronic heartburn, or esophagitis, with a high degree of success.
    Type: Application
    Filed: October 3, 2013
    Publication date: February 6, 2014
    Inventor: ANGEL MANUEL GAGO DE SANTOS
  • Publication number: 20140017337
    Abstract: Therapeutic methods includes several stages, including a modified fasting and low calorie stages, with low impact, moderate exercise, a sliming stage, and a maintenance stage. Nutritional therapeutics are also consumed during each phase, which support a plurality of metabolic and physiological functions.
    Type: Application
    Filed: July 11, 2012
    Publication date: January 16, 2014
    Inventor: Paul Amoruso
  • Patent number: 8568795
    Abstract: A stabilized formulation for skin care, wound care and/or other tissue healing applications and methods for making the same is described. The stabilized formulation stabilizes omega-3 polyunsaturated fatty acids and is constituted of the omega-3 polyunsaturated fatty acids in combination with tocopherol (Vitamin E), ascorbic acid (Vitamin C), herb extract, and a fat-soluble antioxidant. Methods for making and using the stabilized formulation are also described.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: October 29, 2013
    Assignee: Kerecis EHF
    Inventors: Gudmundur Fertram Sigurjonsson, Biljana Ilievska, Baldur Tumi Baldursson
  • Publication number: 20130273129
    Abstract: The present invention relates to insecticide and acaricide paints that inhibit chitin synthesis, regulate insect juvenile hormone and repel arthropods, for controlling endemic diseases, pests and allergens. The paints comprise at least the following compounds (in any combination): 1%-100% water, 0.0001%-20% insecticides, 0.0001%-20% chitin inhibitor, 0.0001%-20% juvenile hormone regulator, 1%-50% polymers, 0%-40% pigments, 0%-60% fillers, 0%-60% natural repellents, and 0.01%-20% stabilizers. The composition of the paints allows the active ingredients to be encapsulated in an aqueous polymer with or without the incorporation of fillers and pigments, and therefore the range of use thereof is increased.
    Type: Application
    Filed: April 12, 2012
    Publication date: October 17, 2013
    Inventor: Maria Pilar MATEO HERRERO
  • Publication number: 20130266638
    Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.
    Type: Application
    Filed: June 3, 2013
    Publication date: October 10, 2013
    Inventors: Annette Tobia, Alice Marcy, Bangying Su, Takeshi Niwa
  • Publication number: 20130259959
    Abstract: The present invention relates to a use of an emulsion comprising an antimicrobial essential oil, acacia gum and water for improving the antimicrobial effect of the essential oil in an aqueous composition, particularly in a food or beverage composition. Further, the invention relates to a process to improve the antimicrobial effect of an essential oil, and aqueous compositions comprising an emulsion of an antimicrobial essential oil, acacia gum and water.
    Type: Application
    Filed: November 24, 2011
    Publication date: October 3, 2013
    Applicant: NESTEC S.A.
    Inventors: Cecile Gehin-Delval, Corinne Appolonia Nouzille, Seow Leng Ng
  • Publication number: 20130263298
    Abstract: A transgenic fly whose genome is modified to express enhanced levels of glutamate-cysteine ligase (GCL) gene is provided. The fly displays phenotypes associated with Alzheimer's disease (AD). Further, a method for diagnosing AD is provided, which includes assessing enzymatic activities in mitochondrial enzymes. Glutathione pathway are investigated by creating Alzheimer's model Drosophila with over-expression of the GCLc gene, inducing redox stress through sleep deprivation, and analyzing mitochondrial electron transport chain (ETC) using colorimetric enzymatic assays. For prevention of AD, it is proposed that the epigenetic approaches be used to increase glutathione levels in vivo before the onset of AD. For treatment of AD, it is proposed that the glutathione levels be increased by GCLc modulation.
    Type: Application
    Filed: March 27, 2013
    Publication date: October 3, 2013
    Applicant: INDIGO CAPITAL GROUP LLC
    Inventors: Lisa P. MICHAELS, Tess P. Michaels
  • Patent number: 8529968
    Abstract: The invention concerns a decontaminating composition having simultaneously bactericidal, fungicidal and virocidal properties, comprising as active components eugenol, eugenol acetate, vanillin and carvacrol, characterized in that said active constituents are present in the following percentages by weight: at least about 12% eugenol, at least about 3% eugenol acetate, at least about 0.1% vanillin and at least about 0.5% carvacrol. Said decontaminating composition can be used as liquid or solid soaps. It can also impregnate in liquid form fabrics and nonwoven fabrics such as garments for medical use, bed sheets, slip covers, surgery drape, dressings and gauze such as those applied to the skin of serious burn victims.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: September 10, 2013
    Assignee: Hightech Bio-Activities Holding GmbH
    Inventors: Hakima Belbachir, Jean Angelidis
  • Patent number: 8518459
    Abstract: This invention concerns a nutraceutical and/or food composition for regulating, among other things, lipid metabolism in humans and animals, and methods of use of said nutraceutical and/or food composition.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: August 27, 2013
    Assignee: Actigenomics S.A.
    Inventors: Walter Wahli, Marie Françoise Yvonne Bourgeois-Lugand, Bernadette Husson-Robert, Gilles Didier Parisot
  • Patent number: 8445033
    Abstract: The invention provides a formulation for the prevention and treatment of bacterial infections by administering an effective amount of the formulation comprising an extract of at least one plant selected from Allium sativum, Acorus calamus, Alstonia scholaris, Carissa spinarum, Cissampelos pareria, Chenopodium ambrosioides, Moringa olifera, Paederia foetida, Shorea robusta, Piper nigrum, Pueraria tuberosa, Ocimum sanctum, Terminalia bellirica, Tinospora cordifolia and Zingiber officinale, and a combination thereof. The invention also provides a process for preparing and method of using the same.
    Type: Grant
    Filed: August 3, 2011
    Date of Patent: May 21, 2013
    Inventor: Ram Chander Vaidya
  • Publication number: 20130115290
    Abstract: Compositions useful for relieving the symptoms commonly known as stomach acidity, heartburn or, more technically, esophageal reflux (GERD), that comprise a fatty acid and a plant extract. These compositions have been tried in patients with clinical records of previous diagnosis of GERD, chronic heartburn, or esophagitis, with a high degree of success.
    Type: Application
    Filed: April 26, 2010
    Publication date: May 9, 2013
    Inventor: Angel Manuel Gago De Santos
  • Publication number: 20130052275
    Abstract: This invention is a topical treatment for the skin, used for skin enhancement, firming, smoothing, refining and to reduce the appearance of cellulite; that has a self-warming or thermogenic effect comprised of a base combination of warming herbs (Ayurvedic), being any herbs that create a warming effect, combined with dietary minerals that can be blended together in any ratio.
    Type: Application
    Filed: August 22, 2012
    Publication date: February 28, 2013
    Inventor: Michelle Ward
  • Patent number: 8372446
    Abstract: The invention herein contemplates an avian feed composition and a method for administering and customizing the feed composition for one or more birds. The feed composition aids in preventing infection and illness including parasitic infestation.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: February 12, 2013
    Inventor: Susan Burek
  • Patent number: 8361517
    Abstract: This invention concerns a composition for regulating lipid metabolism and methods that may be used in the food industry as well as in the nutraceutical and therapeutic fields. In particular, the invention involves food additives or supplements, a composition containing these and the use thereof, in particular for revitalizing a subject's metabolism, in particular, that of human beings.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: January 29, 2013
    Assignee: Actigenomics S.A.
    Inventors: Marie Francoise Yvonne Bourgeois-Lugand, Walter Wahli, Ilhem El Kochairi, Sylvain Pradervand, Giles Didier Parisot
  • Patent number: 8361522
    Abstract: Compositions are disclosed containing, as active ingredients, an extract of Allium species, an extract of Citrus species and either an extract of Paullinia species and an extract of Theobroma species, or an extract of Salix species and zinc sulphate, and the method of preparation of these compositions, and cosmetic and/or pharmaceutical application of these compositions.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: January 29, 2013
    Assignee: Legacy Healthcare Holding Ltd
    Inventors: André Ulmann, Jean-Frédéric Sturer