Containing Or Obtained From Vitis (e.g., Grape, Grapeseed, Wine From Grapes, Etc.) Patents (Class 424/766)
  • Patent number: 10172826
    Abstract: A dietary supplement composition is formulated in a therapeutic amount to treat and alleviate symptoms of hot flashes in a female subject, such as experiencing symptoms of perimenopause. The composition includes a phytoestrogen and lycopene in an oral dosage form. The phytoestrogen may include a plant lignan including at least one of Matairesinol, 7-hydroxymatairesinol, Secoisolariciresinol, Lariciresinol and Pinoresinol. The lycopene may include a lycopene complex having at least one of phytoene, phytofluene, beta-carotene, tocopherols and phytosterols.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: January 8, 2019
    Assignee: U.S. NUTRACEUTICALS, LLC
    Inventors: John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, Jessica Engle
  • Patent number: 10130671
    Abstract: Embodiments described herein provide for uses of grape products, such as Chardonnay grape products and grape seed flour, for use in promoting a healthy liver, promoting healthy fat content in a liver, for treating or preventing NAFLD, and other embodiments and uses as described herein.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: November 20, 2018
    Assignees: SONOMACEUTICALS, LLC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
    Inventors: Torey James Arvik, Hyunsook Kim, Wallace H. Yokoyama, Scott R. Forsberg
  • Patent number: 10105409
    Abstract: The present disclosure relates to health benefits of Chardonnay seed products.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: October 23, 2018
    Assignees: SONOMACEUTICALS, LLC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
    Inventors: Torey James Arvik, Rebecca Susan Lipson, Wallace H. Yokoyama
  • Patent number: 9421189
    Abstract: Disclosed herein is a method of producing a muscadine pomace extract. The method can include combining a bronze muscadine pomace extract with a purple muscadine pomace extract to produce a muscadine pomace extract, wherein the ratio of bronze muscadine pomace extract to purple muscadine pomace extract ranges from 0.1 to 10 (weight to weight), such as from 0.3 to 3 (weight to weight), and the muscadine pomace extract has a polyphenol content of at least 2%. Also disclosed herein is a muscadine pomace extract for use as an antioxidant, such as for use as an anti-aging supplement. The composition can include a muscadine (Vitis rotundifolia) pomace extract having a polyphenol content of at least 2% and other active ingredients.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: August 23, 2016
    Assignee: Shaklee Corporation
    Inventors: Teodoro T. Ianiro, Laurel A. Fisher, William J. Mergens
  • Patent number: 9254280
    Abstract: Nutraceutical formulations that improve cognitive function in adults diagnosed with neurodegenerative disease are provided, which comprise a combination of fisetin and DHA.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: February 9, 2016
    Assignees: The Regents of the University of California, Salk Institute for Biological Studies, U.S. Department of Veterans Affairs
    Inventors: Gregory M. Cole, Sally A. Frautschy, David R. Schubert, Pamela A. Maher
  • Patent number: 9173916
    Abstract: Muscadine grape extracts are disclosed that have antioxidant properties. The extracts are a mixture of extracts from bronze and purple muscadine grapes that unexpectedly increase the solubility of ellagic acid in the mixture. Solvent extracts are obtained in some examples by water extracting the pomaces of the grapes from which the juice has substantially been removed. Further surprising increases in ellagic acid solubility can also be obtained by adding an additional source of anthocyanins to the extract, for example by including in the composition an extract of whole purple muscadine grapes from which substantial amounts of the juice have not been removed. Other additional sources of anthocyanins include blueberries, blackberries and raspberries; the additional source of anthocyanins can be obtained from a fruit processing waste stream to increase the efficiency of the production process.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: November 3, 2015
    Assignee: Shaklee Corporation
    Inventors: Teodoro T. Ianiro, Laurel A. Fisher, William J. Mergens
  • Patent number: 9132162
    Abstract: Antioxidant compositions are disclosed that include muscadine pomace extract and resveratrol from a source other than muscadine. In other examples the composition also includes polyphenols from a source other than muscadine. The compositions increase the expression of antioxidant genes and/or genes associated with mitochondrial biogenesis.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: September 15, 2015
    Assignee: Shaklee Corporation
    Inventors: Laurel A. Fisher, Teodoro T. Ianiro, William J. Mergens, Nasrin Zamanian
  • Publication number: 20150147418
    Abstract: An object of the present invention is to provide a sleep quality improving agent which has a sufficient sleep quality improving effect, can exert makes the effect even through oral administration in any dosage form, and has ensured safety to the body. That is, the present invention provides: a sleep quality improving agent which contains a stilbene-based compound and/or an olive extract as an active ingredient, and a sleep quality improving composition which contains the sleep quality improving agent.
    Type: Application
    Filed: June 26, 2013
    Publication date: May 28, 2015
    Applicant: LION CORPORATION
    Inventors: Yoshihiro Urade, Ikuko Kamada, Toshio Gokita, Kiwamu Suzuki, Hiroaki Kambayashi, Michiaki Murakoshi
  • Patent number: 9040097
    Abstract: Compositions for reducing the appearance of wrinkles, reducing the effects of aging and/or improving the appearance of skin. The composition may include at least one fluorinated perfluorocarbon; stem cells from at least one plant species; and at least one peptide complex that reduces release of acetylcholine. Other embodied compositions include at least one collagen stimulating peptide; at least one anti-inflammatory compound; and at least one skin tightening agent.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 26, 2015
    Assignee: Indermica, Inc.
    Inventors: Eva Claiborne, Jennifer Clara Ellis
  • Patent number: 9040105
    Abstract: A process for the production of nanocrystals or amorphous nanoparticles of actives (nanomaterials), especially from the peels of grapes. A dispersion of a micrometer-sized material in a solution of surfactant or a steric stabilizer is first provided. The macrosuspension is then stirred for at least 1 minute at a rotational speed above 500 rpm using a rotor-stator mixer. The stirred mixture is passed through a jet stream or piston-gas type high pressure homogenizer. The nanomaterials produced can be incorporated into formulations for use as nutraceutical, nutritional supplement, or as supportive treatment in medical therapy. The active can be derived from the peels of grapes.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: May 26, 2015
    Assignee: PHARMASOL GMBH
    Inventor: Cornelia Keck
  • Publication number: 20150139938
    Abstract: The present invention provides methods of promoting arteriogenesis in a subject. Embodiments include methods comprising: administering an effective dose of tocotrienol to the subject; causing an increase in Tissue Inhibitor of Metalloproteinase Metallopeptidase Inhibitor 1 (TIMP1) in vessels of cerebrovascular collateral circulation in the subject; attenuating the activity of Matrix Metalloproteinase-2 (MMP2); thereby promoting arteriogenesis.
    Type: Application
    Filed: June 7, 2013
    Publication date: May 21, 2015
    Applicant: Ohio State Innovation Foundation
    Inventors: Chandan Sen, Cameron Rink, Sashwati Roy, Greg Christoforidis
  • Publication number: 20150132419
    Abstract: The present disclosure relates to health benefits of Chardonnay seed products.
    Type: Application
    Filed: April 29, 2013
    Publication date: May 14, 2015
    Inventors: Torey James Arvik, Rebecca Susan Lipson, Wallace H. Yokoyama
  • Patent number: 9023399
    Abstract: A water-soluble anti-inflammatory cream is disclosed. The cream is a composition of between about 7.5% and about 30% by weight of a healing oil; between about 1% and about 6% by weight of an herbal extract; between about 0% and about 3.5% by weight of microencapsulated amino acids; and at least 39.4% by weight water.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: May 5, 2015
    Assignee: NU Technology, LLC
    Inventors: Irina V Filippova, Leonid K. Filippov
  • Publication number: 20150110907
    Abstract: The invention relates to a method of testing the activity of a potentially active substance to inhibit the enzymatic activity of phospholipase A2. The invention relates notably to a method wherein it comprises a) placing the potentially active substance in the presence with the phospholipase A2; a substrate which is a phospholipid, comprising at least one fatty acid in the form of an ester, the fatty acid is preferably a long chain having between 15 and 22 carbon atoms, this fatty acid preferably being unsaturated or poly-unsaturated, the substrate being capable of releasing at least one fatty acid during its hydrolysis; b) measuring the enzymatic activity of the phospholipase A2, notably comprising detecting the presence of the fatty acid and eventually its quantitative determination. The use of this test method notably enables identifying and selecting an active principle capable of inhibiting the enzymatic activity of phospholipase A2.
    Type: Application
    Filed: December 30, 2014
    Publication date: April 23, 2015
    Inventors: Eric Perrier, Sébastien Bonnet, Delphine Rival
  • Publication number: 20150093459
    Abstract: A bioactive complex composition having enhanced oxidative stability, emulsion stability, mineral rich transparent beverages and a wide range of functional health benefits. The composition may include as a base composition individual ingredients or a synergistic blend of mineral salts, Omega-3 rich oils, phospholipids, chitosan, and alpha-casein, beta-casein, kappa-casein or protein fragments, glycopeptides, phosphopeptides. The composition may optionally be further utilized for the prevention of hypercholesterolemia, bone (and teeth) mineral loss, treatment of mental health diseases, heart health, additional nutritional supplementation, and treatment of additional medical conditions.
    Type: Application
    Filed: October 9, 2014
    Publication date: April 2, 2015
    Inventors: Adela Mora-Gutierrez, Michael H. Gurin
  • Patent number: 8980342
    Abstract: A method of enhancing physical performance during exercise by administering an amount of a grape extract effective to treat a subject. A preferred grape extract comprises a concentration of flavanol monomers of greater than about 5% by weight, and more preferably within a range from about 12% by weight to about 50% by weight, and a concentration of flavanol dimers preferably greater than about 2% by weight, and more preferably within a range from about 6% by weight to about 20% by weight. The flavanol monomers preferably include catechin, epicatechin, epicatechin gallate, and gallic acid. The flavanol dimers preferably include procyanidin B1, procyanidin B2, procyanidin B3, procyanidin B4, and procyanidin B2-O-gallate.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: March 17, 2015
    Assignee: Naturex, S.A.
    Inventors: Benoit Lemaire, Sophie Lafay, Alvin Ibarra, Marc Roller, Jacques DiKansky
  • Patent number: 8980793
    Abstract: The invention relates to phytosanitary formulations. The phytosanitary formulations of the invention comprises at least one active ingredient and at least one alcoholic, hydro-alcoholic or aqueous extract of at least one tinctorial plant. The phytosanitary formulations of the invention can be used in the field of agriculture and horticulture, in particular.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: March 17, 2015
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite Blaise Pascal-Clermont-Ferrand II
    Inventors: Claire Richard, Alexandra Ter Halle, Gérard Ledoigt
  • Patent number: 8974838
    Abstract: A new composition and method are described for male fertility therapy. In one particular embodiment, the composition comprises Lepidium meyenii, carnitine and Coenzyme Q10. When it is administered to males as fertility therapy following the recommended therapeutic regimen, enhanced sperm count, sperm quality, and sperm motility results.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: March 10, 2015
    Assignee: Fairhaven Health, LLC
    Inventors: Kelly Andrews, Amos N. Grunebaum
  • Patent number: 8974842
    Abstract: The present invention relates to a method for preparing a lipophilic extract from lignified portions of vine, such as shoots, stock and roots, characterized in that said method comprises a step for extraction from said lignified portions with an apolar solvent; to an extract obtained by such a method; to the use of such an extract as an excipient in a cosmetic composition; and to a cosmetic composition comprising such an extract.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: March 10, 2015
    Assignee: L V M H Recherche
    Inventors: Virginie Pecher, Patrice Andre
  • Publication number: 20150004264
    Abstract: Disclosed is a composition and method for its use that includes Magnolia bark extract, vitis vinifera extract, tocopherol or tocopherol acetate, and hydrogenated lecithin, lecithin, or dextrin.
    Type: Application
    Filed: May 28, 2014
    Publication date: January 1, 2015
    Applicant: MARY KAY INC.
    Inventors: Jim Faller, David Gan, Michelle Hines, Lisa Mangos
  • Patent number: 8911804
    Abstract: Disclosed is a composition for use as an antioxidant, such as for use as an anti-aging supplement. The composition can include a muscadine (Vitis rotundifolia) pomace extract having a polyphenol content of at least 2% and trans-resveratrol from a source other than muscadine with a minimum purity of at least 5%. In an example, the ratio of muscadine pomace extract polyphenols to trans-resveratrol is in the range of 0.1/1 to 10/1 (weight to weight), thereby providing a composition with antioxidant activity. Also disclosed are methods of producing antioxidant compositions. These methods can include combining a muscadine pomace extract having a polyphenol content of at least 2% and resveratrol from a source other than muscadine with a minimum purity of at least 5% at a ratio in the range of 0.1/1 to 10/1 (weight to weight), thereby providing a composition with antioxidant activity.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: December 16, 2014
    Assignee: Shaklee Corporation
    Inventors: Laurel A. Fisher, Teodoro T. Ianiro, William J. Mergens, Nasrin Zamanian
  • Publication number: 20140348925
    Abstract: The present invention relates to an antioxidant ingredient with low calorie content obtainable by a process that comprises the following steps: (a) selecting as raw material at least one fruit and/or plant material with high antioxidant content, greater than 6 g/100 g dry matter; (b) obtaining juice and pulp by means of grinding, squeezing and/or pressing the raw material; (c) extracting sugars from the pulp obtained in the preceding step in order to produce a pulp with low calorie content; (d) dehydrating the pulp by means of a method selected from air drying, low-temperature drying with application of vacuum and/or freeze-drying; and (e) milling the pulp in order to produce the antioxidant ingredient with low calorie content. Likewise, the invention relates to the process for obtaining said ingredient and to the use thereof for the production of functional foods.
    Type: Application
    Filed: December 20, 2012
    Publication date: November 27, 2014
    Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)
    Inventor: Fulgencio Diego Saura Calixto
  • Patent number: 8895079
    Abstract: A blood lipid lowering agent that functions through a same mechanism as berberine (e.g. berberine, one or more pharmacologically acceptable salts of berberine or a mixture thereof) and a blood lipid lowering agent that functions through a different mechanism than berberine (e.g. phytosterols, phytostanols, esters thereof or mixtures thereof) act synergistically to improve blood lipid profiles, for example, lowering total cholesterol, LDL-C or nonHDL-C, and triglyceride, and increasing the ratio of HDL-C to nonHDL-C. The two may be used in combination to treat or reduce the chance of contracting cardiovascular disease, hyperlipidemia, atherosclerosis, coronary heart disease, angina, cerebrovascular disease, stroke, overweight or obesity, diabetes, insulin resistance, hyperglycemia, hypertension, arrhythmia, diseases of the central nervous system, diseases of the peripheral nervous system and/or inflammation.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: November 25, 2014
    Assignee: National Research Council of Canada
    Inventors: Yanwen Wang, Jeffrey Zidichouski
  • Publication number: 20140341958
    Abstract: The present document describes a microcapsule having silica shells, processes for making the same, processes for functionalizing said microcapsules and processes for encapsulating active agent in said microcapsules.
    Type: Application
    Filed: November 30, 2012
    Publication date: November 20, 2014
    Applicant: LES INNOVATIONS MATERIUM INC.
    Inventors: Mathilde Gosselin, Shaoyong Yu, Nabil Ghezal, Cé Guinto Gamys
  • Publication number: 20140335209
    Abstract: There is provided a process for making a composition suitable for topical application comprising the steps of a) heating at least one fruit and/or vegetable pulp to up to a temperature in the range of about 40° C. to 100° C.; b) mixing between 1 and 40% w/w of a mild base with the heated fruit and/or vegetable pulp. There is also provided a fruit and/or vegetable derived composition suitable for topical application prepared by the above process. There is further provided a fruit and/or vegetable derived composition comprising at least one fruit and/or vegetable-derived pulp and a mild base, said composition having a pH in the range of about 7.5 to about 9.5.
    Type: Application
    Filed: February 12, 2014
    Publication date: November 13, 2014
    Inventor: Thomas James MCARTHUR
  • Publication number: 20140322358
    Abstract: The present invention is generally directed to compositions and methods for amelioration chronic renal failure and related symptoms in domestic animals. In one case, the present invention is directed to a composition for the treatment of chronic renal failure in a domestic animal or symptoms related to chronic renal failure. The composition comprises a Fruit- and Vegetable-Based Additive. In another case, the present invention is directed to a composition for the treatment of chronic renal failure in a domestic animal or symptoms related to chronic renal failure. The composition comprises a Cesium and/or Rubidium salt. In another case, the present invention is directed to a composition for the treatment of chronic renal failure in a domestic animal or symptoms related to chronic renal failure. The composition comprises a Dehydrated Domestic Animal Food and a Phosphate Binder.
    Type: Application
    Filed: April 24, 2014
    Publication date: October 30, 2014
    Inventor: Jeffrey Alan McKinney
  • Patent number: 8871279
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of cancer by administering the herbal composition PHY906 in combination with one or more chemotherapeutic compounds to a mammal undergoing such chemotherapy.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: October 28, 2014
    Assignee: Yale University
    Inventors: Yung-Chi Cheng, Shwu-Huey Liu, Zaoli Jiang, Robert Tilton
  • Publication number: 20140314888
    Abstract: The present invention relates to an anti-inflammatory composition comprising a plant extract and a propolis extract.
    Type: Application
    Filed: September 7, 2012
    Publication date: October 23, 2014
    Applicants: NUTRIVERCELL, Universite Bordeaux Segalen
    Inventors: Loïc Renard, Djavad M. Mossalyai, Jean-Michel Merillon
  • Publication number: 20140301958
    Abstract: The purpose of this patent is to teach the methods of application and compositions of cosmetic and therapeutic products for reducing wrinkle appearance and augmenting certain compartments of the facial integument of a mammal, especially a human. These methods and compositions utilize the hypodermis-targeted release from bioadhesive oral films, pastes or patches applied to oral mucosa or teeth for the purpose of improving the appearance or health of the lips and facial skin.
    Type: Application
    Filed: April 20, 2012
    Publication date: October 9, 2014
    Inventors: Krzysztof Bojanowski, Hui Zhao
  • Patent number: 8846116
    Abstract: The present invention relates to methods and products, such as wet wipes and absorbent articles, that are capable of imparting a health benefit when used in the intended fashion. More specifically, the products described herein comprise one or more botanical compounds, which are capable of selectively controlling the balance of flora on the skin. The compounds may enhance the adherence of healthy flora to the surface of skin or mucosa, inhibit the growth of problem flora on or around the skin surface, or inhibit the adherence of problem flora to the surface of skin or mucosa, or any combination thereof.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: September 30, 2014
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: David W. Koenig, Beth A. Lange, Christine L. Schneider
  • Publication number: 20140271847
    Abstract: There is disclosed a formulation for creating a rapid penile erection within 30 minutes. In an embodiment, a lozenge has a preparation configured to create a rapid penile erection. The preparation is effective to create the rapid penile erection with sildenafil citrate in a range of 50-100 mg. The preparation is effective to create the rapid penile erection with tadalafil in a range of 5-40 mg. The preparation is effective to create the rapid penile erection with vardenafil hydrochloride in a range of 5-40 mg. In various embodiments, the formulation includes a solvent configured to permeate skin. Other embodiments are also disclosed.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Inventors: Ray L. Hauser, BoLin Zheng
  • Publication number: 20140227198
    Abstract: Shelf stable compositions comprising olive extracts are described herein. The compositions include an olive extract comprising hydroxytyrosol, tyrosol, and oleuropein, wherein the weight ratio of hydroxytyrosol to oleuropein is 3:1 or less and the weight ratio of hydroxytyrosol to tyrosol is 2.85:1 or less. The compositions are stable for at least 12 months. Methods of using the shelf stable compositions are also described herein.
    Type: Application
    Filed: February 10, 2014
    Publication date: August 14, 2014
    Applicant: GRADS Holdings LLLP
    Inventor: John Alkire
  • Publication number: 20140220166
    Abstract: Pharmaceutical compositions containing an extract of Houttuynia cordata (THUNB) as an active ingredient for preventing and treating dementia, Parkinson's disease, or epilepsy and methods for using the same. Since the extract of Houttuynia cordata or the mixture of the extract of Houttuynia cordata and the extract of Ampelopsis japonica Makino has a cell protection effect and/or a cognition function improved effect in various models including an Amyloid-? induced dementia model, a scopolamine induced dementia model, a 6-hydroxydopamine (6-OHDA) induced Parkinson's disease model, and a Kainic acid induced epilepsy model, the extract of Houttuynia cordata or the mixture of the extract of Houttuynia cordata and the extract of Ampelopsis japonica Makino may be used as the pharmaceutical composition for preventing and treating dementia, Parkinson's disease, or epilepsy and in health foods for preventing and treating dementia, Parkinson's disease, or epilepsy.
    Type: Application
    Filed: April 10, 2014
    Publication date: August 7, 2014
    Applicant: UNIVERSITY INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Myung Sook Oh, Hyo Geun Kim, Hanbyeol Park
  • Publication number: 20140193368
    Abstract: Synthetic Stem Cell-like Tissue Healing and Regeneration Medication with Anti-inflammatory, Protein Synthesis, Enzyme Deficiency Activation and Genetic Therapy, and Anti-cancer Agent derived from a series of inventions that include these products of Biomolecular Engineering, Drug Discovery from a Biologic Periodic Table of Applied Biochemistry and Biophysics. Tissue has a self healing effect promoting tissue healing and tissue regeneration. Not only does it maintain good health but also it has been observed that the patient's blood is withdrawn from the patient and applied to the ulcer has healing qualities. Cartilage placed in a wound promotes and accelerates wound healing. The anabolic biochemical and biophysical equivalent of tissue has been found in these embodiments to have the same pharmacologic qualities, when devoid of genetic DNA mismatch and other catabolic factors including the catabolic effects of microorganism overgrowth that lacks pro-biotic qualities.
    Type: Application
    Filed: July 10, 2013
    Publication date: July 10, 2014
    Applicant: Immunopath Profile, Inc.
    Inventor: LEONARD S. GIRSH
  • Patent number: 8758839
    Abstract: Disclosed is a composition and method for its use that includes Magnolia bark extract, vitis vinifera extract, tocopherol or tocopherol acetate, and hydrogenated lecithin, lecithin, or dextrin.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: June 24, 2014
    Assignee: Mary Kay Inc.
    Inventors: Jim Faller, David Gan, Michelle Hines, Lisa Mangos
  • Publication number: 20140170246
    Abstract: A topical composition having at least one active agent selected from a depilatory agent(s), an agent(s) for preventing or reducing the growth or re-growth of hair and an agent(s) for preventing or reducing in-growing hair, and a gas, wherein the at least one active agent and gas are dispersed in a cosmetically acceptable medium.
    Type: Application
    Filed: February 20, 2014
    Publication date: June 19, 2014
    Inventors: Magali Bertrand, Philippe Henriat
  • Publication number: 20140161913
    Abstract: The present invention relates to a method for promoting eye health by administering to a companion animal a composition comprising at least one polyphenol selected from the group consisting of rosemary, rosemary extract, coffeic acid, coffee extract, turmeric extract, cucurmin, blueberry extract, grapeseed extract, rosemarinic acid, tea extract, and mixtures thereof.
    Type: Application
    Filed: February 18, 2014
    Publication date: June 12, 2014
    Applicant: The IAMS Company
    Inventors: Jin Zhang, Michael Griffin Hayek
  • Patent number: 8747924
    Abstract: The present invention provide a method for the prevention and treatment of a neurodegenerative disease including Alzheimer's Disease, Huntington's Disease, and Parkinson's Disease, using a grape seed extract or one or more compounds derived therefrom. In particular, the present invention provides a method to treat a patient diagnosed with, or at the risk of developing, a neurodegenerative disease by administering a pharmaceutical composition comprising a grape seed extract or one or more compounds derived therefrom to the patient in a therapeutic amount to reduce the accumulation, aggregation or deposition of amyloid beta or its oligomers, and/or to reduce the misfolding, accumulation and/or aggregation of tau proteins or other proteins.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: June 10, 2014
    Assignee: Icahn School of Medicine At Mount Sinai
    Inventors: Giulio Maria Pasinetti, Lap Ho, Jun Wang
  • Publication number: 20140141088
    Abstract: A water-soluble anti-inflammatory cream is disclosed. The cream is a composition of between about 7.5% and about 30% by weight of a healing oil; between about 1% and about 6% by weight of an herbal extract; between about 0% and about 3.5% by weight of microencapsulated amino acids; and at least 39.4% by weight water.
    Type: Application
    Filed: May 31, 2013
    Publication date: May 22, 2014
    Inventors: Irina V Filippova, Leonid K. Filippov
  • Publication number: 20140134222
    Abstract: The present invention provides a composition comprising an effective amount of benfotiamine and an effective amount of pyridoxamine in a suitable vehicle for topical application. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles, loss of elasticity, and hyperpigmentation caused by chronoaging and/or photoaging of skin, by inhibiting particularly skin damage resulting from reactive carbonyl species (RCS), glycation of skin proteins, formation of advanced glycation endproducts (AGEs) and formation of advanced lipoxidation endproducts (ALEs).
    Type: Application
    Filed: January 17, 2014
    Publication date: May 15, 2014
    Applicant: Tracie Martyn International, Inc.
    Inventor: Marius Morariu
  • Patent number: 8722106
    Abstract: A lip balm composition of natural ingredients, comprising: 54-70 wt. % of one or more oils, 22-28 wt. % beeswax, 3-4 wt. % propolis, 3-5 wt. % pomace, 0.02-3.2 wt. % antioxidant, and optional ingredients, whereby all components add to 100 wt. %.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: May 13, 2014
    Assignee: The MotherVine Nutraceuticals Co. LLC
    Inventor: Fountain Odom
  • Patent number: 8709515
    Abstract: The method comprises steps of: providing a nutraceutical including, in combination, 1.13 to 3 mg lutein and 18.8 to 51.2 mg omega fatty acids and 1.9 to 5.2 mg grape seed extract and 1.9 to 5.2 mg alpha lipoic acid; determining the weight of each dose of the components in the combination based upon an amount per kg body weight of the animal patients; and administering 1 dose of nutraceutical per day to animals suffering from ocular health issues including any degenerative retinal disease and diabetic cataracts and prior to and following cataract surgery for the diminishment and prevention of secondary cataracts.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: April 29, 2014
    Inventors: Carmen C. H. Colitz, Terri L. McCalla, Debra A. Smith
  • Patent number: 8679550
    Abstract: Fortified food and dietary supplement products may be administered to produce desirable physiological improvement. In particular, embodiments of the invention relates to the administration of products enhanced with plant products and iridoids. A study was performed to evaluate the iridoid content, as well as the in vitro and in vivo bioactivities, of a beverage containing noni fruit, Cornelian cherries, and olive leaf extract. The major iridoids present were identified as asperulosidic acid, deacetylasperulosidic acid, oleuropein, morroniside, loganic acid, and loganin In the 2,2-Diphenylpicrylhydrazyl (DPPH) radical scavenging assay, remarkably high in vitro antioxidant activity was observed, with an IC50 of 3.8 ?L/mL. In vivo bioactivities were evaluated in type 2 diabetic Sprague Dawley rats.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: March 25, 2014
    Assignee: Tahitian Noni International, Inc.
    Inventors: Brett Justin West, Claude Jarakae Jensen, Afa Kehaati Palu, Shixin Deng, Jeffery A. Wasden
  • Publication number: 20140079639
    Abstract: Provided herein are methods of culturing cells in vitro in order to exploit the biochemical production ability of the cells to make metabolites that are evaluated and harvested for their biological effects. Also provided are systems for evaluating extracts from such cultured cells to characterize their biological activity(s), particularly with regard to impact on health, wellbeing, longevity, DNA maintenance, mitochondrial health and/or biogenesis, and so forth. Biologically active extracts, components thereof, and compositions (such as cosmetic or pharmaceutical preparations) made comprising such, are also provided.
    Type: Application
    Filed: November 18, 2013
    Publication date: March 20, 2014
    Inventor: David H. McDaniel
  • Patent number: 8668921
    Abstract: The present invention provides lipase inhibitors containing dimers of flavan-3-ols derived from teas as well as foods and beverages and medicines containing said inhibitors. More specifically, the present invention provides lipase inhibitors containing at least one of assamicains represented by the formula: wherein G represents a galloyl group; theasinensins represented by the formula: wherein R1 represents G or H, and R2 represents G; and theaflavins represented by the formula: wherein R1 and R2 independently represent G or H; as well as foods and beverages and medicines containing said lipase inhibitors.
    Type: Grant
    Filed: July 5, 2005
    Date of Patent: March 11, 2014
    Assignee: Suntory Holdings Limited
    Inventors: Masaaki Nakai, Yuko Fukui, Sumio Asami, Fumio Hashimoto
  • Patent number: 8663709
    Abstract: A new composition and method are described for male fertility therapy. In one alternative, the composition utilizes three nutritional supplements, Lepidium meyenii, L-carnitine, and Coenzyme Q10. When it is administered to males as fertility therapy following the recommended therapeutic regimen, enhanced sperm count, sperm quality, and sperm motility results.
    Type: Grant
    Filed: April 28, 2010
    Date of Patent: March 4, 2014
    Assignee: Fairhaven Health, LLC
    Inventors: Kelly Andrews, Amos N Grunebaum
  • Patent number: 8658218
    Abstract: A composition for treating damaged tissue and promoting healthy tissue growth, healing and tissue regeneration, wherein the composition comprises an extracellular matrix compound, a surface-active lipid, one or more enantiomericaily pure L-amino acids or glycine, a hydrophilic surfactant with a high HLB, as well as vitamins, minerals or trace elements. Not only does it maintain good health, but the components are non-intrusive, bio-safe, non-coalescent and can mimic normally occurring stem-cells within a body. When applied to diseased tissues, the subject compositions can stimulate, facilitate, and accelerate protein synthesis for the regeneration of diseased organs and tissues. The healing efficacy of these tissue components gives us further appreciation of the protective action of human tissue over and above and other than the immune protective system or perhaps an integral component part of the immune system.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: February 25, 2014
    Assignee: Immunopath Profile, Inc.
    Inventor: Leonard S. Girsh
  • Publication number: 20140023719
    Abstract: A Salvia hispanica L. derived seed oil extract composition of matter containing from 60-88% PUFAs in a ratio of from 3.1:1-3.3:1 of ALA to LA, 4-10% of C-18 mono-unsaturated fatty acid, 1-5% of C-18 saturated fatty acid and 4-8% of C-16 saturated fatty acid in a mixed triglyceride form stable at room temperature of 12-24 months containing a mixture of selected antioxidants.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 23, 2014
    Applicant: U.S NUTRACEUTICALS,LLC d/b/a Valensa International
    Inventors: John A. Minatelli, W. Stephen Hill, Rudi E. Moerck, UY Nguyen
  • Publication number: 20140023737
    Abstract: Method for modulating oxidative stress, inflammation, and impaired insulin sensitivity in a subject by using a grape seed extract, the method being useful in modulating post-prandial oxidative stress, inflammation, and impaired insulin sensitivity in patients suffering from Metabolic Syndrome (MetS).
    Type: Application
    Filed: March 15, 2013
    Publication date: January 23, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
  • Publication number: 20130316029
    Abstract: The invention provides methods, compositions, and dietary formulations useful for managing blood glucose, preventing or treating insulin resistance, and improving insulin sensitivity. The methods comprise administering to an animal a therapeutically effective amount of a combination of at least two of one or more antioxidants; one or more anti-glycation agents; one or more body fat reducing agents; one or more insulin sensitivity enhancing agents; and one or more anti-inflammatory agents.
    Type: Application
    Filed: December 15, 2011
    Publication date: November 28, 2013
    Applicant: NESTEC S.A.
    Inventors: Yuanlong Pan, Rondo Paul Middleton, Steven Scott Hannah