Abstract: The present invention deal with a process to obtain a decoction from Vitis labrusca and Vitis skins; process to obtain a hydro-alcoholic and hydro-alcoholic-ethyl acetate obtained from the decoction; pharmaceutical preparations containing the decoction and the before mentioned extracts and therapeutic utilization of the preparations and the prevention and treatment of arterial hypertension and other cardiovascular diseases. The decoctions and the extracts, when administered orally to rats with spontaneous arterial hypertension, hypertension induced by chronically inhibition of nitric oxide synthesis or induced by DOCA-salt administration induced a significant reduction of the high levels of arterial blood pressure. Capsules and tablets were prepared with the decoctions and extracts.

Abstract: The present invention relates to a one step process for the preparation of antibacterial and antioxidant fraction from the unconventional parts of Seabuckthorn (Hippophae rhamnoides L.).

Abstract: The present invention refers to a dietary supplement containing all of the natural components of wine, except for the volatile ones, in particular ethanol. Said dietary supplement is suitable for oral administration and contains antioxidant complexes present in wine vinasses combined with one or more bioavailability promoters. A preferred embodiment of the invention consists in a dietary supplement provided as solid or liquid formulation allowing for avoidance of wine consumption while maintaining all of the beneficial components, in particular the antioxidant ones.

Abstract: The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type Escherichia coli. These extracts can be obtained from any proanthocyanidin-containing plants, including plants of the families Ericaceae, Rosaceae, Pinaceae, Vitaceae and the like. Preferably the extracts are from cranberry plants (especially, Vaccinium macrocarpon) and other plants, particularly fruit and berry plants from the Vaccinium spp. The extracts and compounds are also provided as pharmaceutical compositions, food additives and food compositions, especially beverages, ground meat preparations and cranberry-containing food products. The invention also relates to methods of reducing pathogenicity of P-type E. coli in the digestive tracts of cattle and reducing P-type E. coli contamination in ground meat as well as methods of detecting P-type bacteria.

Abstract: There are provided topical cosmetic compositions for improving the aesthetic appearance of skin and remediating the effects of aging, and methods of use thereof. One composition is a blend of neem seed cell broth and one or more additional botanical ingredients. Another composition has pomegranate fruit extract and, optionally, one or more additional botanical ingredients.

Abstract: The present invention relates to a composition for the optimization of the adaptive immune system based on aged garlic extract, to a process for preparing the same, and to a method of administration or usage with a specific dosage schedule. The composition is free from unpleasant after body odors or side-effects. The invention of this disclosure uses a well-known herb/food as a supplement/medicinal agent, namely garlic, which when prepared and aged in combination with brandy alcohol, and utilized as disclosed herein, is effective with upper respiratory infections, colds, and influenza prevention for up to 2 years, easy to use, and less expensive than similar products available in the market. A method for preparing said composition is disclosed.

Abstract: The present invention is a fungicidal solution and method for controlling fungal disease in plants which provides for contacting the plant matter with a fungicidally effective application of an aqueous solution. The fungicidal solution is comprised of between about one-third (⅓) to two-third (⅔) cup of an organic plant matter to every two-third (⅔) gallon of a fermented solution. The organic solution may be any type of sage, tea leaves, coffee leaves, beech leaves, eucalyptus leaves, oak leaves, sumac leaves, and other similar leaves, or bark. The fermented solution contains between about (1%) one percent to (25%) twenty-five percent, per gallon, of an alcohol and grape juice.

Abstract: A preparation based on plant extracts, with an antioxidant action which is particularly useful in the treatment of circulation and chronic degenerative problems and in the treatment of hypertension, characterized in that its active ingredients comprise Ginkgo biloba biflavones, catechin and/or epicatechin, cumarin and derivatives thereof and a component selected from among madecassic acid, asiatic acid, asiaticoside or combinations thereof.

Abstract: The present invention involves a composition for oral ingestion that contains effective amounts of Glucosamine sulfate, Nettle Leaf, Quercetin, curcumin extract/curcuminoids, Selenium, Zinc, Vitamin C (calcium ascorbate) and Grape Seed Extract, as well as other ingredients and healthy filler ingredients. More specifically, this formulated product is a cartilage and joint maintenance and repair formulation. This formulation allows for enhanced function of joints and cartilage to treat and prevent osteoarthritis, rheumatoid arthritis and other joint ailments/diseases.

Abstract: A food supplement which has beneficial effects for bowel health, and a method of preparing the food supplement are disclosed. The food supplement is derived from fiber extracts from two or more types of fruit or vegetables. The fiber extracts have a majority of soluble solids removed therefrom. The two or more types of fruit or vegetable may be selected from the group consisting of grape, citrus, apple, tomato, carrot, mango, cranberry, papaya, banana, pineapple, kiwi fruit, spinach and melon. The beneficial effects for bowel health are manifest in an increase in levels of short chain fatty acids (SCFA's) in the colon.

Abstract: Pharmaceutical and cosmetic compositions for the protection of the skin from damages induced by sun radiations, containing ingredients of vegetable origin, in addition to conventional sun filters and excipients.

Abstract: Disclosed are methods products such as wet wipes and absorbents capable of providing a skin health benefit when utilized in the intended fashion. More specifically, the products described herein comprise an antioxidant agent, such as a botanical extract, which is capable of reducing the amount of oxidation on the skin's surface resulting in improved skin health. The antioxidant agent has an antioxidant potential at three minutes of at least about 25% as determined by a AST Antioxidant Status Test set forth herein. In another embodiment, the antioxidant agent has an antioxidant potential at thirty minutes of at least about 20% as determined by a AST Antioxidant Status Test set forth herein.

Abstract: The present invention relates to a neurochemical formulation comprising a supplement for improving function of neurons, improving memory and cognitive abilities, and reversing free radical damage caused by aging or neurodegenerative disease. The formulation comprises phosphoesters and antioxidants. Components may have antioxidant properties or enhance properties of other components. The synergistic combinations allow individual component dosages to be reduced, thereby minimizing potential toxicity.

Abstract: A composition of matter generally relating to a joint and arthritis pain formula with a unique and optimized blending of ingredients to promote the healing and relief of arthritis symptoms, with an added chelated and bio-energized delivery system to insure proper absorption, assimilation, and digestion.

Abstract: The invention features compositions containing an antioxidant and/or a gingkolide compound to reduce inflammation. Combination drug therapy using antioxidant and/or a gingkolide compound with an anti-inflammatory agent reduces adverse side effects associated with many known anti-inflammatory agents.

Abstract: The present invention provides an ATP synthesis activator which allows the promotion of ATP synthesis in the body and results in an increased ATP level in the body for a long period of time. The ATP synthesis activator comprises, as an active ingredient, a mixture of a plurality of herbs having an ion-exchange capacity. It may stimulate electron generation in the body and hence results in an improved ATP synthesis activity due to the generated electrons, because dietary fiber contained in the herbs has an ion-exchange capacity.

Abstract: The invention relates to a dietary supplement consisting of an aqueous extract of red vine leaves and an acceptable carrier which prevents and reduces the discomfort relating to mild-to-moderate chronic venous insufficiency of the legs.

Abstract: A natural skin lotion, salve or conditioner made from wholesome, naturally grown organic plants for reconditioning and regulating skin conditions and the use of such a natural, healthful skin lotion with the benefits of alternative healing elements, namely crystal therapy to produce benefits which can reach beyond the physical, and to emotional well being.

Abstract: The present invention is directed to a method of processing a fat-containing bean, e.g., cocoa beans, for producing solids comprising active polyphenols and/or fat-containing products, comprising extracting the fat to produce solids and fat-containing products. Additionally, the inventive method also provides cocoa compositions comprising at least one active polyphenol, wherein the concentration of the polyphenol(s) with respect to the nonfat solids is conserved with respect to the concentration of the active polyphenol(s) in the bean from which the compositions are derived.

Abstract: An oral care composition comprising: (i) an effective amount of a antibacterial seed or pulp extract from the Citrus plant family; the Vitis plant family; and mixtures thereof; (ii) an oral care active selected from the group consisting of anti-calculus agents; anti-plaque agents; fluoride ion source; desensitizing agents; oral malodor control agents; H2 antagonists; and mixtures thereof; and (iii) a pharmaceutically acceptable carrier.

Abstract: The invention relates to a composition intended for administration by the oral or topical route and comprising, in a physiologically acceptable medium, DHEA and/or a chemical or biological precursor or derivative of the latter, in combination with at least one NO-synthase inhibitor.

Abstract: There is provided a hair tonic comprising at least two of an inhibitor against 5&agr; reductase type 2, an inhibitor against transforming growth factor &bgr;2, and an inhibitor against caspase-3; a method comprising screening for at least two of inhibition against 5&agr; reductase type 2, inhibition against transforming growth factor &bgr;2, and inhibition against caspase-3, or comprising screening for inhibition against caspase-3 and then for apoptosis inhibition, and a hair loss inhibitor having the effect of inhibiting caspase-3, and a hair loss inhibitor having the effect of inhibiting caspase-3 and of inhibiting apoptosis.

Abstract: Enhanced dermatological compositions are described herein using from about 21 to about 40 wt-% urea with antioxidant skin protectants suitable for the treatment of icthyosis, xerosis, severely dry skin, dermatitis, eczema, debridement and tissue suffering and other similar skin conditions.

Abstract: The invention relates to a composition for pharmaceutical or dietary use that possesses antioxidant activity and characterized in that it contains as active principle a combination of catechin quercetin, which exert a synergistic action when combined in mutual molar ratios selected within a critical range, from 6:1 to 3:1 mol of catechin:quercetin.

Abstract: The invention relates to a cosmetic preparation containing an active complex comprised of plant extracts. The active complex contains at least one starting substance, which is extracted as an aqueous extract from real truffles (Tuberaceae) and which is provided in a cosmetically acceptable gel while being stabilized. A preferred active complex is one that additionally contains a champagne product. Cosmetic preparations containing this active complex lead to an improved stimulation of the immune system, an improved regenerative effect and thus to an improved balance in the ecosystem of the skin.

Abstract: The invention relates to a method for improving the cell protection which comprises the administration of a combination of the extracts of the plants Vitis vinifera and Lycopersicon esculentum with the vitamins C, E, beta-carotene and optionally selenium. Said combination can be used in the prevention of phatological conditions related in part to an overproduction of free radicals like aging, arteriosclerosis and cancer.

Abstract: The present invention relates to a composition comprising Melissa leaf extract that inhibits angiogenesis and matrix metalloproteinase activity. The Melissa leaf extract of the present invention inhibits angiogenesis and activity of matrix metalloproteinase, so that it can be applied to treat or prevent diseases related to angiogenesis and matrix metalloproteinase. The composition of the present invention comprising Melissa leaf extract may also comprise more than one component of the other anti-angiogenic, anti-cancer, anti-inflammatory and anti-aging components. This particular composition comprising Melissa leaf extract can be used for pharmaceutical, dietetic and/or cosmetic purposes.

Abstract: Compositions and methods for reducing or eliminating the appearance of cellulite. The method involves administering to a patient in need of treatment therapeutically effective amounts of a sugar compound that is converted to a glycosaminoglycan in the patient in an amount sufficient to thicken the skin, a primary antioxidant component in an amount sufficient to substantially inhibit the formation of collagenase and elastase, at least one amino acid component in an amount sufficient to assist in the thickening of the skin, and at least one transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin so as to reduce or eliminate the appearance of cellulite. A preferred method of treatment further includes administering the components above in conjunction with a vascular dilator to improve blood supply to the skin and/or a fat burner to reduce absorption or digestion of fat in the digestive tract or to prevent the production of fat.

Abstract: A powerful formulation for preventing and treating macular degeneration, cataracts, glaucoma and other eye diseases, and contains over thirty naturally effective vitamins, minerals, phytonutrients and amino acids, which have all been found to demonstrate a powerful protective effect on the health of the eye.

Abstract: The present invention relates to compositions and absorbent articles including compositions for protecting the skin barrier. The compositions can be applied to the bodyfacing surfaces of absorbent articles so that the compositions come into contact with the skin. The compositions of the invention provide several benefits including prevention and alleviation of skin irritations associated with the use of absorbent articles. The compositions can include hydrophilic and non-aqueous components as well as extracted botanical actives.

Abstract: A preferred composition containing a skin whitening blend containing bearberry and an antioxidant, such as tetrahydrocurcumin, is provided. Also the composition can comprise a hypopigmenting component selected from mulberry, scutellaria, grape, cowberry, bilberry, molasses, pear, guava, licorice, etc. The licorice extract can be in the form of a water soluble extract or an oil soluble extract. Other antioxidants can be selected from rosemary extract, tocopherol, green tea extract, and gamma oryzanol. The skin whitening blend may also have an accelerant that enhances or accelerates the skin cell turnover rate. The skin whitening blend may also include a sunscreen component. Also, the composition may further include a pH adjusting agent, a surfactant, a thickening agent, a preservative, a fragrance, a masking agent, a pigment, an emulsifier, and/or emollient.

Abstract: The invention concerns firstly a food complement for dietetic and/or cosmetic purposes, containing anti-lipase properties, for oral administration. Said food complement is characterised in that it comprises a grape extract rich in or enriched with polyphenols.

Abstract: A method of treating onychomycosis is described which includes administration of a topical formulation containing an effective amount of urea and an antioxidant to an infected area around a nail of a patient.

Abstract: The lees or “dregs” produced during wine making are rich sources of antioxidants. Unexpectedly, these materials show significant antibacterial properties as well as antioxidant properties. The lees of red wine which consist of tannins and plant pigments precipitated around crystals of potassium tartarate can advantageously be used directly as a tonic or demulcent. The material can also be used topically for disinfecting the skin, etc. In addition, it is possible to use organic polymers to bind the pigments and/or solubilize them from the tartaric salt to facilitate their use or to make a relatively pure pigment/tannin component.

Abstract: The invention relates to a method for improving the cell protection which comprises the administration of a combination of the extracts of the plants Vitis vinifera and Lycopersicon esculentum with the vitamins C, E, beta-carotene and optionally selenium. The combination can be used in the treatment prevention of pathological conditions related in part to an overproduction of free radicals like aging, arteriosclerosis and cancer.

Abstract: The use of the residues from wine production as active substance preparations in the production of cosmetic and/or pharmaceutical preparations is disclosed.

Abstract: Disclosed is a composition that includes a material that is susceptible to degradation and a preserving agent in an amount effective to preserve the material comprising one or more reduced malto-oligosaccharide species. The preserving agent can include a single reduced malto-oligosaccharide species or a plurality of such species. Further disclosed is a method of preserving a material. The method generally includes contacting the material with a preserving agent containing a preserving effective amount of one or more reduced malto-oligosaccharide species. Solutions, powders, glasses, gels, and the like containing the chemically reactive material(s) and a preserving effective amount of one or more reduced malto-oligosaccharide species may be prepared.

Abstract: The present invention relates to a novel synergistic herbal composition for the treatment of gastric ulcer, a method for preparing said synergistic herbal composition and a process for the treatment of gastric ulcer using said composition and more particularly, the present invention relates to a novel synergistic herbal composition which is effective against pyloric ligation induced ulcer model and histamine induced ulcer model.

Abstract: The present invention is a fungicidal solution and method for controlling fungal disease in plants which provides for contacting the plant matter with a fungicidally effective application of an aqueous solution. The fungicidal solution is comprised of between about one-third (⅓) to two-third (⅔) cup of an organic plant matter to every two-third (⅔) gallon of a fermented solution. The organic solution may be any type of sage, tea leaves, coffee leaves, beech leaves, eucalyptus leaves, oak leaves, sumac leaves, and other similar leaves, or bark. The fermented solution contains between about (1%) one percent to (25%) twenty-five percent, per gallon, of an alcohol and grape juice.