Abstract: The present invention relates to a skin external preparation containing pine pollen or pine pollen extract. The pine pollen or pine pollen extract inhibits a growth of the acne bacterium Propionibacterium acnes and exhibits an effect of reducing comedos, and thus is effective for the prevention and treatment of acne. Preferably, the pine pollen or pine pollen extract is contained in an amount ranging from 0.05% by weight to 50% by weight, based on the total weight of the skin external preparation.

Abstract: A composition which is effective as a skin whitening agent is disclosed. The composition includes Simmondsin. In certain embodiments, the composition comprises an extract of jojoba. A method of promoting skin whitening, comprising the step of topically administering to an individual a composition in an amount effective to whiten skin, where that composition comprises a jojoba extract.

Abstract: An anti-HSV agent that inhibits the replication of HSV-1 and HSV-2 that is derived from a plant. Further, provided is a method of producing a potassium hydroxide extract of pine cone having anti-HSV activity, and the Anti-HSV agent.

Abstract: The present invention relates to a diet composition comprising raw foods comprising the lyophilized powders of grains, vegetables and seaweeds; dietary fibers; and functional herbal extracts, etc. The composition according to the present invention is effective in reduction of weight and body fat and body shape management as well as abundant in nutrition ingredients. And also the composition has an excellent effect on decreasing cholesterol and neutral fat amounts in blood. Therefore, the composition according to the invention can be usefully employed as a food capable of preventing or improving obesity while assisting in ingesting nutriments, which are apt to be lacking in modern people, without omission.

Abstract: Composition and methods for improving air quality, disinfecting surfaces, and prevention of a respiratory infection. The method can decrease pathogen and/or parasitic concentrations in closed rooms and surfaces by the application of an antiseptic composition. The composition can be a pressurized or foaming solution containing a single terpene, a terpene mixture, and/or a liposome:terpene(s) combination with or without surfactant. The composition can be a true solution of an effective amount of an effective terpene and a carrier such as water. The composition can be a suspension or emulsion of terpene, surfactant, and carrier. Application can be, for example, by spraying a confined space with a solution of the present invention.

Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.

Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.

Abstract: The present invention provides a skin-improving agent which comprises, as an active ingredient, proanthocyanidin in which the extent of galloylation per constitutive monomer is 10% or lower (molar ratio).

Abstract: A process for preparing dry extracts from a liquid extract and at least one additional substance by a spray-drying process, characterized in that said at least one additional substance is added to the spray-drying process in a dry form during the spray-drying processes.

Abstract: The objetive of the present invention was to enhance the skin whitening effects and blackening prevention effects and supply safe and stable topical agents for dermatological use. For that purpose 4-Hydroxyphenyl-&agr;-D-glucopyranoside was combined with auxiliary agents such as ascorbic acid and its derivatives, crude drugs and its extracts, hydroxycarboxylic acid and its salts, oil soluble glycyrrhiza extract, gentian extract, phenol derivatives and their salts, placenta extract, kojic acid and its derivative, glucosamine and its derivatives, azelaic acid and its derivatives, retinol and its derivatives, pyridoxin and its derivatives, tocopherol and its derivatives, chitosan and its decomposition products, caffeic acid derivatives, hydroxycinnamate and its derivatives, Umbelliferae plant extracts, mycelial cultures and their extracts, plant leaves and their extracts.

Abstract: This present invention details slow-release natural and safe compositions for use in repelling clothes moths and other insects from all types of closed storage units. Specifically, the compositions contain a blend of Generally Regarded as Safe (GRAS) essential oils and some of their active ingredients, used currently as food additives including but not limited to, geranium oil, rosemary oil, peppermint oil, mint oil, citronella oil, thyme oil, cinnamon oil, geraniol, and eugenol. More specifically, the compositions further contain citric acid and acetic acid, all applied to a substrate.

Abstract: The use of a flavonoid extract is described to treat a mammal for at least one of the treatments including: reducing a redox imbalance associated with disease in a mammal; preventing oxidative stress in a mammal; reducing oxidative stress in a mammal; preventing protein oxidation in a mammal; reducing protein oxidation in a mammal; preventing DNA damage in a mammal; reducing DNA damage in a mammal; and combinations thereof. A method of treatment of a mammal is also described. The treatments have the advantage of maintaining health in an individual.

Abstract: A composition including a dose of flavonoids extracted from pine bark extract is described that decreases the rate of senescence of a mammal after onset of senescence. The same compound also increases mammal lifespan and increases neuromuscular performance after onset of senescence. Methods of treatment and use of this composition are also described. The composition has the advantage of being a useful general aging remedy to avoid many common age related decreases in performance.

Abstract: The invention provides methods for treating medical conditions caused by abnormal chloride ion flux with compositions containing active ingredients isolated from the traditional Chinese medicine Bao-Ji-Wan (BJW). The compositions comprise any one, two, or three of the following: magnolol, honokiol, imperatorin, isoimperatorin or only magnolol, honokiol, imperatorin, isoimperatorin and a physiologically acceptable carrier. In preferred embodiments, the medical conditions include disorders of the gastrointestinal tract, such as diarrhea and constipation.

Abstract: The invention herein relates to a topical liquid composition for promoting hair growth, comprising natural ingredients with no side-effects, which is effective in promoting hair growth and preventing hair loss. More particularly, the invention relates to the topical liquid composition for promoting hair growth, comprising the extracts which are formed by immersing the mixture of powders of Pinelliae Rhizoma, Caryophylli Flos, Rubi Fructus, Zanthoxyli Fructus, Viticis Fructus, Salviae Radix, and Thujae Semen in oil and ethanol, respectively, followed by aging for a fixed period of time.

Abstract: A method of determining a dosage of anti-oxidant for an individual person, wherein the dosage is determined on the basis of an individual factor and a stress index. The individual factor is based on a weight factor of the individual, an age factor of the individual and a training factor of the individual. The training factor is based on training history of the individual, and the stress index is based on current and future physical activity of the individual. A formulation based on this method is also described.

Abstract: Herbal compositions and methods suitable for weight loss management and for treating diabetes are disclosed. The compositions comprise Ferula hermonis or an extract thereof, or Ferula hermonis with selected herbs, extracts thereof, and mixture thereof. The methods of reducing weight, and treating diabetes in patients involve oral administration of the compositions. The invention further relates to a method of extracting and standardizing Ferula hermonis extracts and tincture useful for human health.

Abstract: The present invention relates to a method of removing organic acid an/or organic amines odors from aqueous systems by treating the aqueous system or the atmosphere adjacent to the aqueous system with a solution of a substantially sulfonate free, anionic kraft pine lignin.

Abstract: This invention relates to IL-4 production inhibitors, antiallergic agents and atopic dermatitis preventives and improvers, each of which contains at one or more compounds selected from the group consisting of hydroxyl-containing monoterpenes, hydroxyl-containing sesquiterpenes and their acylated derivatives. This invention is also concerned with IL-4 production inhibitors, antiallergic agents and atopic dermatitis preventives and improvers, each of which contains an essential oil such as cedarwood oil. This invention is also concerned with bath medicine compositions, each of which contains one or more ingredients selected from cedrol, cedrenol, farnesol, patchouli alcohol and vetiverol.

Abstract: This invention relates to IL-4 production inhibitors, antiallergic agents and atopic dermatitis preventives and improvers, each of which contains at one or more compounds selected from the group consisting of hydroxyl-containing monoterpenes, hydroxyl-containing sesquiterpenes and their acylated derivatives. This invention is also concerned with IL-4 production inhibitors, antiallergic agents and atopic dermatitis preventives and improvers, each of which contains an essential oil such as cedarwood oil. This invention is also concerned with bath medicine compositions, each of which contains one or more ingredients selected from cedrol, cedrenol, farnesol, patchouli alcohol and vetiverol.

Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising_of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.

Abstract: This invention relates to nutrient and therapeutic compositions for treatment and prevention of symptoms and disease conditions associated with microangiopathy and macroangiopathy and to methods using the compositions. In particular, the invention relates to compositions useful in the treatment of diabetic retinopathy and nephropathy, to compositions useful in the treatment of other retinal disorders including macular degeneration and cataracts, to compositions useful in wound healing, to compositions useful for treatment and prevention of neuropathy, to compositions useful for treatment and prevention of cardiovascular disease and to compositions useful for the treatment and prevention of dental and periodontal disorders.

Abstract: An improved medical treatment and medicine is provided to quickly and safely resolve HIV and other microbial infections. The inexpensive medicine can be self administered and maintained for the prescribed time. The attractive medicine comprises an antimicrobial concentrate comprising microbe inhibitors, phytochemicals or isolates. Desirably, the effective medicine comprises a surfactant and an aqueous carrier or solvent and a nutrient. In the preferred form, the medicine comprises: Echinacea and Commiphora myrrha phytochemicals, benzalkonium chloride, a sterile water solution, and folic acid.

Abstract: An improved medical treatment and medicine is provided to quickly and safely resolve herpes and other microbial infections. The inexpensive user-friendly medicine can be applied and maintained on the infected region until the physical symptoms of the disease disappears and the patient is comfortable and has a normal appearance. The attractive medicine comprises an antimicrobial concentrate comprising microbe inhibitors, phytochemicals or isolates. Desirably, the effective medicine comprises a surfactant and an aqueous carrier or solvent. In the preferred form, the medicine comprises Echinacea phytochemicals and benzalkonium chloride in a sterile water solution.

Abstract: Remedies for allergic diseases obtained by mixing shoots of plants belonging to the family Pinaceae with water and saccharides followed by spontaneous fermentation. As the plants belonging to the family Pinaceae, it is preferable to use plants belonging to the genus Pinus. These remedies, which enable complete recovery in a short administration time without showing any side effects, are useful as remedies for allergic diseases, in particular, asthma and atopic dermatitis. Also, a yeast isolated from these remedies for allergic diseases is provided.

Abstract: A method is provided for deactivating a Der-p and/or Der-f allergen which comprises volatilizing into a space to be treated a deactivating amount of a volatile oil selected from cajeput oil (tea tree oil) or an oil comprising one or more terpene hydrocarbons.

Abstract: The present invention provides a lip treatment formulated with Morinda citrifolia juice or oil. The Morinda citrifolia lip treatment of the present invention serves to provide significant health and lip care advantages.

Abstract: A number of discrete, isolated and well-characterized natural plant compounds show antimicrobial activity when used for topical applications in the ophthalmic, skin care, oral care, pharmaceutical, medical device, heath care products or similar preparations for topical application. Of particular interest are Allantoin, Berberine, Bilberry extract, Caffeic Acid Phenethyl Ether, Chlorogenic Acid, Cranberry Extract, Elderberry Extract, Ferulic Acid, Green Tea Extract, Grape Seed Extract, Hydroxytyrosol, Oleuropein, Olive Leaf Extract, Pine Bark Extract, Pomegranate Extract, Pycnogenol, Quercetin, Resveratrol, and Tart Cherry Extract. Oleuropein, and Pomegranate Extract, either alone or in combination, is extremely effective. Allantoin, can be used to enhance the efficacy of synthetic chemical disinfecting/preservative agents as well as to mitigate the cytotoxicity of some synthetic chemical disinfecting/preservative agents.

Abstract: An anti-HSV agent that inhibits the replication of HSV-1 and HSV-2 that is derived from a plant. Further, provided is a method of producing a potassium hydroxide extract of pine cone having anti-HSV activity, and the Anti-HSV agent.

Abstract: An anti-inflammatory agent exhibiting an anti-inflammatory function is provided, which includes either a set of dried substances or an extract of Perilla leaf, Cacao and Fennel, and preferably Perilla leaf, Cacao, Fennel, Fenugreek seed, Rosemary, Juniper berry and Celery seed. This specific set or combination of those natural herbs is effective to relax and suppress symptoms of allergy, particularly holistic symptoms of allergic rhinitis, without causing any substantive adverse effects. Since all of the ingredients included in agent are derived from the natural herbs, a long-term administration of the agent may cause substantively no adverse effects. Also, inclusion of the agent into foods and drinks is also useful.

Abstract: An adhesive composition includes a polymerizable adhesive monomer and at least one dual function stabilizer. The stabilizer provides superior stabilization and shelf-life of the composition, and enhances wound healing properties of the monomer composition.

Abstract: An anti-inflammatory agent exhibiting an anti-inflammatory function is provided, which includes either a set of dried substances or an extract of Perilla leaf, Cacao, Fennel, Fenugreek seed, Rosemary, Juniper berry and Celery seed. This specific set or combination of those natural herbs is effective to relax and suppress symptoms of allergy, particularly holistic symptoms of allergic rhinitis, without causing any substantive adverse effects. Since all of the ingredients included in agent are derived from the natural herbs, a long-term administration of the agent may cause substantively no adverse effects. Also, inclusion of the agent into foods and drinks is also useful.

Abstract: Our invention concerns a mixture of CLA glycerides, and/or CLA-fatty acids and or CLA-alkyl esters and another component, wherein the other component (=component A) is selected for its capacity to alleviate problems related to insulin resistance in mammals, using CLA rich diets and/or foods and/or food supplements using an appropriate in vitro test so that in at least one step of the in vitro test, as described in the text, an improvement in test results is obtained of at least 4% by the blend of the CLA derivative and component A when compared to the CLA derivative only.

Abstract: Compositions of plant carbohydrates for dietary supplements and nutritional support for promotion and maintenance of good health. Defined nutritionally effective amounts of one to eleven essential saccharides, glyconutrients, are used in various inventive compositions as dietary supplements. The dietary composition herein can include phytonutrients, vitamins, minerals, herbal extracts, and other non-toxic nutrients. The glyconutritional dietary supplement herein provides essential saccharides which are the building blocks of glycoproteins. These compositions, when administered orally or topically, have been found to improve the well being of mammals suffering from a variety of disorders.

Abstract: A method of producing a pine cone extract and the pine cone extract produced there from, wherein the pine cone extract is useful in increasing the effects of nucleic acid vaccines and medicaments; and useful in the production of phenotypically immature and/or mature dendritic and/or fibrocyte cells.

Abstract: A synergistic insecticide is provided by the addition of sodium lauryl sulfate or lecithin to an essential oil, preferably an essential oil which has been deregulated by the Environmental Protection Agency, to enable independently inactive or relatively inactive materials to provide commercially acceptable insecticidal properties without the need for undesirable poisons that may be toxic to humans and pets.

Abstract: The present invention relates to a cosmetic or pharmaceutical composition for topical application to the skin afflicted with rosacea and treated with a retinoid. The composition for treating rosacea comprises an anti-irritating component and several other components for treating rosacea. The other components form a mixture of a salicylic acid, a phytosphingosine, green tea, hinokitiol, gorgonian extract, and polysaccharide. The invention also provides a method for decreasing the irritation on the skin caused by the heightened sensitivity experienced by skin suffering from rosacea. The other components are effective in treating the rosacea condition, but particularly, in treating the telangiectasic symptom of rosacea.

Abstract: Compositions and methods are provided for activation of endogenous plant pathogen resistance pathways, including systemic acquired resistance, the hypersensitive reaction response and the upregulation of pathogenesis related proteins. The compositions comprise as active agents one or more naturally occurring compounds or essential oils selected from cedar oil, cinnamon oil, grapefruit oil, grapefruit seed extract oil, ferulic acid and acetyl salicylic acid. The methods involve directly applying formulations comprising one or more of these active agents to a Gymnosperm to induce endogenous plant defense pathways as a therapeutic or prophylactic treatment against fungal pathogens such as pitch canker and white pine blister rust.

Abstract: This invention relates to a method of relaxing mammals comprising administering to said mammals a personal care composition which comprises an effective amount of a sensory fragrance that is effective in reducing cortisol levels and/or increasing sIgA levels.

Abstract: A method for treating wood, characterized by impregnating wood with a metal-containing treating agent containing lignin and/or lignin derivatives and a metal, a metal compound, and/or a metal ion and oxidizing and/or macromolecularizing of the lignin and/or lignin derivatives in the wood to fix the metal component in the wood, and wood and woody materials obtained by the treating method. According to the method of the present invention, while effectively utilizing lignins, lignosulfonic acids, or lignosulfonic acid salts, leaching of the metal component can be suppressed to a low level to thereby retain the effects due to the incorporation of the metal components for a prolonged period.

Abstract: A bioflavanoid rich potent extract and process for the extraction from oak bark and pine bark that is highly enriched in proanthocyainds. The present invention provides for component liquids comprised of approximately 2% active ingredients of gallic acids and tannic acids which are then added to other inactive ingredients which include corn syrup and flavoring.

Abstract: This invention relates to the isolation of compound namely (−)-wikstromol and together with or associated with a therapeutically acceptable additive and useful as hepatoprotective agent.

Abstract: The invention concerns an enzymatic method for making oenological tannins starting with lumps of wood and an enzymatic method for transforming tannins into tannins for wine-making purposes. The inventive method comprises a step which consists in contacting the lumps of wood or tannins with an aqueous solution comprising a composition containing enzymes of the cellulase class. The invention also concerns an enzymatic composition mainly consisting of enzyme of the cellulase class for making oenological tannins, comprising an endocellulase activity, a xylanase activity a &bgr;-mannanase and/or &agr;-amylase activity.

Abstract: Method for obtaining tannin by extracting plant resources with mangrove, acacia, pine, eucalyptus, oak, hemlock and the like with lower alcohol or lower alcohol/water, or extracting outer bark of radiata pine (Pinus radiata) with water, lower alcohol or lower alcohol/water, and an adhesive containing said extracted substance for adhering woody materials such as veneer.

Abstract: Aquarium water and a preparation method thereof, including a fermented solution of a mixture of extract from leaves of a ginkgo tree, extract from ganoderma, extract from bark of a chestnut tree, extract from acorns, extract from leaves of an evergreen oak tree, extract from bamboo, extract from leaves of a persimmon tree, extract from leaves of a pine tree, water-soluble chitosan powder extracted from crab shells, barley natural stone powder, bamboo salt, potato starch, and distilled water. Fermentation is by adding yeast, and organic germanium, mineral component extracted from yellow soil, and extract from combustion of an oak tree are added. The solution is then fermented again and refined in a liquid state.

Abstract: The invention concerns a slimming cosmetic composition characterized in that it includes PNP as active agent and, more particularly, a plant extract containing PNP.

Abstract: Methods for isolating taxol and derivatives thereof with high purity are described. The methods include a supercritical fluid and a cosolvent extraction step, a liquid—liquid separation step, and a column chromatography step. An apparatus for isolating Taxol and derivatives thereof that allows the method steps to be performed online also is described.

Abstract: The present invention relates to a composition of a hair growth facilitator comprising camphor extract, morus bark root extract, new shoot extract of a pine tree, and fibrous biopolymer produced by silkworm cocoons. By having a superior hair growth effect without any known side effects or toxicities, the present invention can resolve the drawbacks present in the conventional compositions of hair growth facilitators and thus can be safely applied to various hair-related products such as hair tonic, hair lotion, hair cream, hair shampoo and hair conditioner.

Abstract: An improved method for the treatment of melanoma and skin tumors which utilizes a zinc chloride composition is provided. The zinc chloride composition allows the surgeon to obtain hemostasis after a biopsy, and to incise or excise a melanomatous or other skin tumor through painless, bloodless, dead tissue. Because the microscopic structures are fixed in place by the zinc chloride, excised tissue can be examined microscopically by a pathologist. This invention allows the active ingredients of zinc chloride compositions to be effectively administered to the skin by providing single-use dose specific storage, application, dressing, and administration systems needed to facilitate the use of the topical zinc chloride mixtures. Enhanced zinc chloride mixture formulations including herbal taxoids are described.

Abstract: The present invention relates to a treating method for hair growth inhibition, which comprises administering (A) the extract of a plant of the family Juniperus or a malt. In addition, the present invention relates to a dermatologic composition for external use, which comprises (B) an elastase inhibitor or neutral endopeptidase inhibitor, and the above-described component (A) and/or (C) at least one proteolytic enzyme selected from the group consisting of papain, trypsin, chymotrypsin, pepsin, bromelain, ficin and pancreatin.