Anti-infective Patents (Class 424/78.07)
  • Patent number: 9629913
    Abstract: Topical formulations for application to exposed body tissue.
    Type: Grant
    Filed: February 9, 2014
    Date of Patent: April 25, 2017
    Assignee: AIDANCE SKINCARE AND TOPICAL SOLUTIONS, LLC
    Inventors: Perry Antelman, David Goldsmith, Shalom Lampert
  • Patent number: 9497962
    Abstract: The present invention is related to an improved method of foaming hydroalcoholic solutions having between 60% and 80% ethanol (by weight) present. The compositions of the present invention are useful as hand sanitizer compositions. The compositions of the present invention provide copious dense foam, and an outstanding skin feel upon evaporation of the water and alcohol.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: November 22, 2016
    Assignee: S.LTECH LLC
    Inventor: Anthony J. O'Lenick, Jr.
  • Patent number: 9480678
    Abstract: Disclosed is an antifungal agent for external use, which is characterized by containing a compound represented by the general formula (1), 50 to 95 mass % of an alcohol such as ethanol, 0.1 to 35 mass % of water or the like, and 0.01 to 5 mass % of a cellulose thickening agent. X is a halogen or H.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: November 1, 2016
    Assignees: POLA PHARMA INC., NIHON NOHYAKU CO., LTD.
    Inventors: Takaaki Masuda, Naoto Nishida, Naoko Kobayashi, Hideaki Sasagawa
  • Publication number: 20150132238
    Abstract: Disclosed are compositions comprising crosslinked hyaluronic acid gels, preferably vinyl sulfone cross-linked hyaluronic acid known as hylan B gel, for use in topical cosmetic and dermatological formulations. The hylan B gel in these formulations provides prolonged delivery of incorporated substances to the surface of the skin, to provide a hydrated film on the surface of the skin, and to provide a substantive and compatible film on the skin.
    Type: Application
    Filed: January 23, 2015
    Publication date: May 14, 2015
    Inventors: Adelya K. Leshchiner, Nancy E. Larsen, Edward G. Parent
  • Publication number: 20150132237
    Abstract: Disclosed are compositions comprising crosslinked hyaluronic acid gels, preferably vinyl sulfone cross-linked hyaluronic acid known as hylan B gel, for use in topical cosmetic and dermatological formulations. The hylan B gel in these formulations provides prolonged delivery of incorporated substances to the surface of the skin, to provide a hydrated film on the surface of the skin, and to provide a substantive and compatible film on the skin.
    Type: Application
    Filed: January 23, 2015
    Publication date: May 14, 2015
    Inventors: Adelya K. Leshchiner, Nancy E. Larsen, Edward G. Parent
  • Patent number: 9028852
    Abstract: Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including a cationic antiseptic such as biguanides and bisbiguanides such as chlorhexidine and its various salts including but not limited to the digluconate, diacetate, dimethosulfate, and dilactate salts; polymeric quaternary ammonium compounds such as polyhexamethylenebiguanide; silver and various silver complexes; small molecule quaternary ammonium compounds such as benzalkoium chloride and alkyl substituted derivatives; di-long chain alkyl (C8-C18) quaternary ammonium compounds; cetylpyridinium halides and their derivatives; benzethonium chloride and its alkyl substituted derivatives; and octenidine. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component.
    Type: Grant
    Filed: September 7, 2004
    Date of Patent: May 12, 2015
    Assignee: 3M Innovative Properties Company
    Inventor: Matthew T. Scholz
  • Patent number: 8992901
    Abstract: The invention is in the field of skin hygiene, especially hand hygiene and/or hand soap compositions. It remains to be desired to prepare skin hygiene compositions having a high anti-microbial effect, even with a low dosage of anti-microbial essential oils. It is therefore an object of the invention to provide a skin hygiene composition, having good anti-microbial properties, at low levels of essential oil. Surprisingly it has been found that composition comprising a low amount of at least two essential oils and a polymer provides improved hygiene efficacy.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: March 31, 2015
    Assignee: Conopco, Inc.
    Inventors: Sameer Keshav Barne, Kalpana Kamalakar Nayak, Aravindakshan Perincheery, Maya Treesa Saji
  • Patent number: 8961873
    Abstract: The present invention describes a new system and method, named “Antinfection”, to protect primarily healthcare workers (HCWs) and patients against communicable and nosocomial infections. It's based on new antiseptic sprays, non-alcoholic, that can be sprayed automatically on the hands. The base of the antiseptic action is the persistent part, preventing the colonization of tissue and non-living surfaces with microorganisms through the targeted, on-demand release of Fluorine ions. The system including new sprayers for fast and controlled application; new technologies to secure the long-term protection against wear in the daily work routines of HCWs; new measurement techniques for the quality of the Antinfection; new quality recording concepts for the promotion and verification of new strategies and campaigns in the “lost war against the germs”.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: February 24, 2015
    Inventors: Fridolin Voegeli, Ghanem E. Ghanem
  • Patent number: 8940797
    Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: January 27, 2015
    Assignee: Ecolab USA Inc.
    Inventors: Joseph R. Wegner, Cheryl A. Littau
  • Patent number: 8940281
    Abstract: Disclosed are compositions comprising crosslinked hyaluronic acid gels, preferably vinyl sulfone cross-linked hyaluronic acid known as hylan B gel, for use in topical cosmetic and dermatological formulations. The hylan B gel in these formulations provides prolonged delivery of incorporated substances to the surface of the skin, to provide a hydrated film on the surface of the skin, and to provide a substantive and compatible film on the skin.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: January 27, 2015
    Assignee: LuroMed LLC
    Inventors: Adelya K. Leshchiner, Nancy E. Larsen, Edward G. Parent
  • Publication number: 20150023904
    Abstract: The present invention relates to an application of povidone iodine (PVP-I) in the preparation of a medicine treating premature ejaculation, wherein the medicine is the compound consisting of PVP-I and any other biologically compatible carrier, such as PVP-I disinfectant or Andoful PVP-I disinfectant. The beneficial effect is: by experiment, PVP-I is proved to be able to increase patients' ILET and have a significant therapeutic effect for those suffering premature ejaculation.
    Type: Application
    Filed: June 19, 2013
    Publication date: January 22, 2015
    Inventor: Bo Song
  • Publication number: 20150024017
    Abstract: A solid buffer including one or more ion exchange materials, wherein said solid buffer has a volumetric buffering capacity greater than about 20 mM H+/(L·pH unit) and further wherein, when said material is in an environment capable of transporting H+ ions, said solid buffer is adapted to cause the death of at least one target cell within or in contact with said environment. A selectively permeable barrier layer may be provided covering the solid buffer.
    Type: Application
    Filed: April 11, 2014
    Publication date: January 22, 2015
    Applicant: OPLON PURE SCIENCE, LTD.
    Inventors: Shmuel BUKSHPAN, Gleb ZILBERSTEIN
  • Publication number: 20140356313
    Abstract: A dermal protector liquid including a barrier and antimicrobial materials is disclosed. The protector liquid can be sprayed onto the skin. The protector liquid can have a dispersant and moisturizer. When the base and solvents of the liquid evaporate, a polymer barrier and antimicrobial material can continue to reside on the skin.
    Type: Application
    Filed: August 18, 2014
    Publication date: December 4, 2014
    Inventor: Marie H. JHIN
  • Patent number: 8900553
    Abstract: A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: December 2, 2014
    Assignee: Foamix Pharmaceuticals Ltd.
    Inventors: Dov Tamarkin, Helena Shifrin, Rita Keynan, Enbal Ziv, Tal Berman, David Schuz, Elana Gazal
  • Publication number: 20140348890
    Abstract: The invention relates to a wound dressing having a backing and an antimicrobial wound contact layer, wherein the wound contact layer has a hydrophobized active ingredient.
    Type: Application
    Filed: August 8, 2014
    Publication date: November 27, 2014
    Applicant: LOHMANN & RAUSCHER GMBH & CO. KG
    Inventor: MARIUS-THOMAS GORKA
  • Patent number: 8895542
    Abstract: Disclosed is a medicinal cream that includes flisidic acid which is made in situ under an oxygen-free environment using sodium fusidate. The fusidic acid is made by dissolving the sodium fusidate in a co-solvent under inert gas purging and under vacuum, and converting the sodium fusidate to fusidic acid in situ by adding an acid under stirring, The disclosed medicinal cream also includes a biopolymer and a cream base comprising at least one of each of a primary and secondary emulsifier, a waxy material, and water.
    Type: Grant
    Filed: April 12, 2010
    Date of Patent: November 25, 2014
    Inventors: Vanangamudi Subramaniam Sulur, Madhavan Srinivasan, Neelakandan Narayanan Chulliel, Haridas Sankar, Kuppusamy Senthilkumar
  • Publication number: 20140328776
    Abstract: Compositions, kits and methods of preparing a biocompatible film for cosmetic or medical uses are disclosed. The compositions or kits contain polyvinyl acetal (PVA), siloxane and a solvent. The siloxane can have a hydrophilic group. Once the solvent content is reduced, for instance, by evaporation, the mixture of PVA and siloxane is solidified, forming a film. The compositions and kits, optionally, further include one or more of an antimicrobial agent, a pigment, an anti-inflammatory agent, an anesthetic agent or a hemostatic agent. Such a film can be used, for example, in the form of an antimicrobial sealant, a liquid bandage, body paints, scar camouflage, water-proof sun block, makeup sealer, or antimicrobial wipe or spray.
    Type: Application
    Filed: July 16, 2014
    Publication date: November 6, 2014
    Inventor: SHAOSHENG DONG
  • Publication number: 20140308331
    Abstract: This invention relates to compositions and applications for an interpolymer network delivery system containing iodine.
    Type: Application
    Filed: August 12, 2012
    Publication date: October 16, 2014
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Joachim B. Kohn, Carmine P. Iovine, Niraj Ramachandran
  • Publication number: 20140286884
    Abstract: Disclosed are compositions comprising crosslinked hyaluronic acid gels, preferably vinyl sulfone cross-linked hyaluronic acid known as hylan B gel, for use in topical cosmetic and dermatological formulations. The hylan B gel in these formulations provides prolonged delivery of incorporated substances to the surface of the skin, to provide a hydrated film on the surface of the skin, and to provide a substantive and compatible film on the skin.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 25, 2014
    Applicant: LUROMED LLC
    Inventors: Adelya K. Leshchiner, Nancy E. Larsen, Edward G. Parent
  • Patent number: 8840932
    Abstract: Antiseptic compositions, as well as methods of making and using, wherein the compositions include: an antimicrobial agent selected from the group consisting of iodine (I2), an iodophor, and a combination thereof, wherein the antimicrobial agent is present in an amount sufficient to provide an available iodine concentration of at least about 0.25 wt-%; a hydroxycarboxylic acid buffer in an amount of at least about 5 wt-%; water; and an optionally substantive film-forming polymer.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: September 23, 2014
    Assignee: 3M Innovative Properties Company
    Inventors: Matthew T. Scholz, Danli Wang, Triet M. Lu, Dong-Wei Zhu
  • Publication number: 20140271529
    Abstract: Disclosed herein are antifungal compositions and methods of using the same to treat secondary skin and nail infections.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: ALC Therapeutics, LLC
    Inventors: Martin STOGNIEW, Robert ALONSO, Joseph CAPRIOTTI, Kara CAPRIOTTI, Stuart LESSIN
  • Patent number: 8821848
    Abstract: A composition and method useful in promoting hemostasis, absorbing ooze, and being antimicrobial with respect to an open wound. The composition broadly includes an antimicrobial agent, preferably povidone iodine, preferably a ferrate compound, and a cation ion exchange resin. This composition will destroy a biofilm which has formed over the open wound in providing a soluble iron compound, a cation chelation compound, and an active antimicrobial compound effective against planktonic microorganisms and biofilms. The antimicrobial agent is locked or sealed within the scab formed over the wound to maintain long-term positioning and anti-dilution of the antimicrobial over the wound.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: September 2, 2014
    Assignee: Biolife, L.L.C.
    Inventors: Talmadge Kelly Keene, John Hen
  • Patent number: 8821910
    Abstract: The present application relates to oligomeric antimicrobial compounds and compositions comprising the same. The oligomers are formed by polymerizing aminoalkyl(meth)acrylate or aminoalkyl(meth)acrylamide monomer(s). In addition to imparting materials with broad spectrum antimicrobial activity, the oligomers can impart antimicrobial activity to substrates such as hair and skin.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: September 2, 2014
    Assignee: BASF SE
    Inventors: Zhiqiang Song, Ted Deisenroth
  • Patent number: 8795714
    Abstract: Described is an intra-mammary teat sealant and a corresponding method of forming a physical barrier in the teat canal of a non-human animal for prophylactic treatment of mammary disorders during the animal's dry period. The method includes the step of infusing a bismuth-free teat seal formulation into the teat canal of the animal. The method also prevents the formation of black spot defect in dairy products, especially cheddar cheese, made from the milk of animals so treated.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: August 5, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: Scott A. Rankin
  • Publication number: 20140212370
    Abstract: The present invention provides a method of treating a skin ailment including administering to a subject in need thereof, a therapeutically effective amount of a composition including (i) a primary diamine; (ii) a secondary aromatic diamine; (iii) a polyisocyanate; and (iv) optionally, a polyol. The present invention also provides a method of forming a skin bandage.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: Chesson Laboratory Associates, Inc.
    Inventors: Jerry S. Chesson, Timothy J. Romack, Lance L. Swick, David R. Terry
  • Publication number: 20140205559
    Abstract: Improvements in or relating to manually operated dispense heads for fluid containers
    Type: Application
    Filed: May 8, 2012
    Publication date: July 24, 2014
    Applicant: ALC THERAPEUTICS, LLC
    Inventors: Joseph Capriotti, Kara Capriotti
  • Patent number: 8778365
    Abstract: The present invention relates to improved topical gel compositions comprising an active agent, and uses thereof.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: July 15, 2014
    Assignee: Merz Pharmaceuticals, LLC
    Inventors: Bhushan Hardas, Donna Dalton
  • Publication number: 20140193355
    Abstract: A denial protector liquid including a barrier and antimicrobial materials is disclosed. The protector liquid can be sprayed onto the skirt. The protector liquid can have a dispersant and moisturizer. When the base and solvents of the liquid evaporate, a polymer barrier and antimicrobial material can continue to reside on the skin.
    Type: Application
    Filed: January 7, 2013
    Publication date: July 10, 2014
    Inventors: Marie H. JHIN, Hanafi TONOJO
  • Patent number: 8747856
    Abstract: The present invention relates to the use of a fully human antigen binding fragment of an antibody for the manufacture of a medicament for the treatment or diagnosis of an ocular disease upon topical administration. The invention further relates to a pharmaceutical composition comprising a fully human binding fragment of an antibody for ocular topical administration for treatment or diagnosis of an ocular disease. In particular, the antibody neutralizes HSV1 and HSV2.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: June 10, 2014
    Assignee: Ribovax Biotechnologies S.A.
    Inventors: Claire Abadie, Jean-Marc Combette, Catherine Deloche, Robert Anthony Williamson
  • Patent number: 8734771
    Abstract: Powder treated with a powder treating agent comprising organohydrogenpolysiloxane, characterized in that the organohydrogenpolysiloxane has a weight average molecular weight of from 300 to 100,000, at least one SiH bond per molecule, and at least one selected from (R23SiO1/2) unit and (SiO2) unit, wherein R1 is selected from the group consisting of a hydrogen atom, and alkyl, fluorinated alkyl, aryl and aralkyl groups each having 1 to 30 carbon atoms.
    Type: Grant
    Filed: March 1, 2007
    Date of Patent: May 27, 2014
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Masanao Kamei, Kiyomi Tachibana
  • Patent number: 8709385
    Abstract: Pharmaceutical or cosmetic compositions and methods for their use are provided comprising water and a surfactant polymer system comprising a Poloxamer at a concentration of about 0.1% to about 15% by weight; wherein when the Poloxamer is between about 0.1% to about 5% Poloxamer. The composition can further comprise a supporting agent comprising a non-ionic surface active agent or a supporting agent comprising a non surfactant polymer or polysaccharide and an active agent, where the Poloxamer is capable of fixing the composition on delivery to a body surface. There are further provided therapeutic cell compositions and their uses.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: April 29, 2014
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Alex Besonov, Tal Berman, David Schuz, Elana Gazal
  • Patent number: 8709439
    Abstract: The invention provides a biological dressing for treatment of a dermatological disease comprised of one or more resins or other film-forming agents, a topically acceptable volatile solvent, and a pharmacologically active agent. The combined one or more resins are present in a suitable amount such that the composition, when the solvent evaporates, will dry to form a solid coating that sticks to the skin, nail or mucosal membrane to which the composition is applied, and maintain the pharmacologically active agent over a sustained period of time in contact with sites on the skin or mucosal membranes exhibiting symptoms of the disease. Methods are provided for treating symptoms of dermatological diseases with such a pharmacological composition.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: April 29, 2014
    Assignee: Jaleva Pharmaceuticals, LLC
    Inventor: Alex Battaglia
  • Patent number: 8691255
    Abstract: This invention relates to a method of producing and dispensing a foam using a “high lower alcohol content” (>40% v/v of a C1-4 alcohol) liquid composition. The liquid compositions comprise an alcohol, C1-4 (>40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and moisturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: April 8, 2014
    Assignee: Deb Worldwide Healthcare Inc.
    Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
  • Patent number: 8685422
    Abstract: This invention relates to a “high lower alcohol content” (>40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise a C1-4 alcohol, (>40% v/v), a silicone-based surfactant of at least 0.001% by weight for foaming to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: April 1, 2014
    Assignee: Deb Worldwide Healthcare Inc.
    Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
  • Patent number: 8685381
    Abstract: The invention provides skin protecting and penetrating, easy-to-administer base and active agent-containing compositions, such as those including hydrocortisone, for treating the skin of mammals for different dermatologic disorders. This is effected by topically administering effective amounts of the compositions thereto in forms that address the skin and mucosa of the mouth and lips, and the rest of the body. Additionally, an optional flavoring addition to these products affords significantly better tasting, and less bitter, compositions, allowing a more pleasant experience and better compliance by patients. The compositions include a unique formulation of FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and, optionally, one or a plurality of plant or plant seed oils, fatty alcohols, fats and flavorings, in desirable weight percents thereof, in various forms, and preferably in a form of a solid roll-on stick in a variety of sizes and of a jar or pot.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: April 1, 2014
    Inventors: Joel Schlessinger, Daniel Isaac Schlessinger
  • Patent number: 8679516
    Abstract: This invention relates to a “high lower alcohol content” (>40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise an alcohol, C1-4 (>40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and moisturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: March 25, 2014
    Assignee: Deb Worldwide Healthcare Inc.
    Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
  • Patent number: 8673356
    Abstract: The present invention relates to stable fixed dose topical formulations comprising an antiacne agent and an antibiotic, which exhibit storage stability at a temperature of about 40° C. and relative humidity of about 75% for a period of at least 3 months. Particularly, the present invention relates to stable fixed dose topical formulations comprising therapeutically effective amounts of (a) adapalene-containing microspheres and (b) clindamycin, a process for their preparation thereof and their use for the treatment of acne.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: March 18, 2014
    Assignee: Glenmark Pharmaceuticals Limited
    Inventors: Ulhas Rameshchandra Dhuppad, Nitin Babulal Bhamre, Sunil Sudhakar Chaudhari, Girish Ramakrishna Trivedi, Akhilesh Dayanand Sharma, Prashant Dongre
  • Patent number: 8658701
    Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: February 25, 2014
    Assignee: Ecolab USA Inc.
    Inventors: Joseph R. Wegner, Cheryl A. Littau
  • Publication number: 20140030209
    Abstract: A topical liquid agent for a nail and/or skin for prevention or treatment of dermatophytosis comprises a film-forming agent and a compound represented by the formula: wherein R1 represents hydrogen, C1-6 alkyl, or trifluoromethyl, R2 represents hydrogen, C1-6 alkyl, halogen, —COO(C1-6 alkyl), or (CH2)1-3COOR where R represents hydrogen or C1-6 alkyl, R3 represents hydrogen, C1-6 alkyl, amino, trifluoromethyl, or OR where R represents hydrogen or C1-6 alkyl, R4 represents hydroxyl, R5 represents hydrogen, C1-6 alkyl, hydroxyl, or halogen, R6 represents hydrogen, C1-6 alkyl, trifluoromethyl, halogen, amino, —NRaRb, nitro, hydroxy-C1-6 alkyl, —CONRaRb, —COO(C1-6 alkyl), —COOH, —(CH2)1-3COOR, or ORa where R represents hydrogen or C1-6 alkyl, Ra and Rb each represent hydrogen, C1-6 alkyl, or C1-6 acyl, R7 represents hydrogen, C1-6 alkyl, —OR where R represents hydrogen or C1-6 alkyl, or halogen, R8 represents hydrogen, C1-6 alkyl, hydroxyl, amino, or nitro, or a salt thereof.
    Type: Application
    Filed: July 30, 2013
    Publication date: January 30, 2014
    Inventors: Yoshiko FURUTA, Kazuki KOMATSU, Arpansiree KAYA, Sho TAKAHATA, Yuji TABATA
  • Patent number: 8591876
    Abstract: Provided herein are methods of using gaseous nitric oxide and/or at least one nitric oxide source to or decrease sebum production in the skin of a subject. In some embodiments, the nitric oxide source includes small molecule and/or macromolecular NO-releasing compounds.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: November 26, 2013
    Assignee: Novan, Inc.
    Inventors: Susanne Bauman, Nathan A. Stasko
  • Patent number: 8586067
    Abstract: A microbicidal and antiseptic composition, which comprises the following (a), (b) and (c): (a) at least one kind of alcohols selected from the group consisting of ethanol and isopropanol; (b) at least one kind of carboxyvinyl polymers selected from the group consisting of polyacrylic acids, polyacrylates, copolymers of polyacrylic acids and polyacrylic acid alkyl esters, and copolymers of polyacrylates and polyacrylic acid alkyl esters; and (c) agar.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: November 19, 2013
    Assignee: Maruishi Pharmaceutical Co., Ltd.
    Inventors: Kazuki Okamoto, Tsuyoshi Miura, Manabu Soga, Yutaka Nishihara
  • Patent number: 8586008
    Abstract: The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelf-life of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: November 19, 2013
    Assignee: Stiefel West Coast, LLC
    Inventors: Albert Zorko Abram, Lilian Fuchshuber
  • Patent number: 8574609
    Abstract: Broad spectrum disinfecting and microbicidal compositions of biodegradable and environmentally friendly compositions containing esters formed from fatty organic alcohols and fatty carboxylic acids. These compositions display activities against the most resistant microbial forms including bacterial spores. The preparations can be used in health care, food processing, personal care and other industries where the use of harsh oxidizing chemicals is undesirable.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: November 5, 2013
    Inventor: John Alex Lopes
  • Publication number: 20130287724
    Abstract: Liquid formulations having anti-adherent properties are disclosed herein. The liquid anti-adherent formulation described herein acts to prevent the adherence of menses and/or fecal material to the skin in the labial and perianal regions during and after menstruation or defecation, respectively. The liquid anti-adherent formulation contains a carrier, a polymer selected from an anionic polymer, nonionic polymer, and combinations thereof. Anti-adherent formulation was found to be effective if a menses leave-on percentage as defined within the Menses Leave-On Percentage Test method described herein of less than 7.2% after two insults.
    Type: Application
    Filed: April 30, 2012
    Publication date: October 31, 2013
    Inventors: Douglas R. Hoffman, Stacy A. Mundschau, Corey T. Cunningham, Dave A. Soerens
  • Patent number: 8568753
    Abstract: A microbicidal delivery system including: a microbicidal composition including a microbicidal compound including a dendrimer including one or more surface groups of formula (IV); a microbicidally active derivative thereof, or pharmaceutically acceptable salt or solvate thereof; and a carrier, excipient or diluent therefor; and a prophylactic device; the microbicidal composition being carried on a surface of the prophylactic device and being compatible therewith.
    Type: Grant
    Filed: February 1, 2006
    Date of Patent: October 29, 2013
    Assignee: Starpharma Pty Limited
    Inventors: Owen Timothy Grogan, Thomas David McCarthy
  • Patent number: 8530524
    Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: September 10, 2013
    Assignee: Ecolab USA Inc.
    Inventors: Joseph R. Wegner, Cheryl A. Littau
  • Patent number: 8512718
    Abstract: A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: August 20, 2013
    Assignee: Foamix Ltd.
    Inventors: Meir Eini, Dov Tamarkin
  • Patent number: 8486375
    Abstract: The present invention is related to a foamable composition of matter comprising iodine, water, a foam adjuvant, a surface-active agent and a gelling agent. This foamable composition, which may be provided in a propellant free foaming device, or alternatively may further comprise a propellant, evolves into foam, which is effective in the topical treatment and prevention of various skin disorders.
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: July 16, 2013
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Doron Friedman, Meir Eini
  • Publication number: 20130171089
    Abstract: The present invention is directed towards various topical protective formulations which may be used as an adjunct in preventing the spread of a broad range of sexually transmitted diseases. The product is intended to be used as a topical lotion, cream, emulsion, or the like. The film forming excipients and active ingredients in the following formulations have demonstrated unique skin protective barrier properties with enhanced persistence that inhibits transmission of sexually transmitted diseases.
    Type: Application
    Filed: February 27, 2013
    Publication date: July 4, 2013
    Inventor: CLJI IP Company, LLC
  • Patent number: 8475770
    Abstract: The present subject matter provides foamable suspension gels that foam after release from a container. The foamable suspension gels contain at least one pharmaceutically active agent that is sparingly soluble to insoluble in water, a second pharmaceutically active agent, and optionally a third active agent.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: July 2, 2013
    Assignee: Stiefel Research Australia Pty Ltd
    Inventors: Albert Zorko Abram, Lilian Fuchshuber