Anti-infective Patents (Class 424/78.07)
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Publication number: 20130171089Abstract: The present invention is directed towards various topical protective formulations which may be used as an adjunct in preventing the spread of a broad range of sexually transmitted diseases. The product is intended to be used as a topical lotion, cream, emulsion, or the like. The film forming excipients and active ingredients in the following formulations have demonstrated unique skin protective barrier properties with enhanced persistence that inhibits transmission of sexually transmitted diseases.Type: ApplicationFiled: February 27, 2013Publication date: July 4, 2013Inventor: CLJI IP Company, LLC
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Patent number: 8475770Abstract: The present subject matter provides foamable suspension gels that foam after release from a container. The foamable suspension gels contain at least one pharmaceutically active agent that is sparingly soluble to insoluble in water, a second pharmaceutically active agent, and optionally a third active agent.Type: GrantFiled: September 2, 2011Date of Patent: July 2, 2013Assignee: Stiefel Research Australia Pty LtdInventors: Albert Zorko Abram, Lilian Fuchshuber
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Publication number: 20130121953Abstract: The disclosure describes a composition including about 4 weight percent to about 12 weight percent of povidone-iodine complex, about 0.1 weight percent to about 2 weight percent of a tertiary amide, tertiary amide salt, and/or tertiary amide hydrate, about 0.5 weight percent to about 2 weight percent of an emollient with low iodine reactivity, at least one surfactant; and water; wherein the composition has a pH ranging from about 2.0 to about 3.5.Type: ApplicationFiled: October 31, 2012Publication date: May 16, 2013Applicant: MICRODERMIS CORPORATIONInventor: Microdermis Corporation
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Publication number: 20130089510Abstract: Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.Type: ApplicationFiled: May 8, 2012Publication date: April 11, 2013Applicant: Foresight Biotherapeutics, Inc.Inventors: Joseph A. Capriotti, Bo Liang, C. Michael Samson, Jason Stein, Michael Weiser
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Patent number: 8409556Abstract: The present invention is directed towards various topical protective formulations which may be used as an adjunct in preventing the spread of a broad range of sexually transmitted diseases. The product is intended to be used as a topical lotion, cream, emulsion, or the like. The film forming excipients and active ingredients in the following formulations have demonstrated unique skin protective barrier properties with enhanced persistence that inhibits transmission of sexually transmitted diseases.Type: GrantFiled: October 17, 2011Date of Patent: April 2, 2013Assignee: CLJI IP Company, LLCInventors: Craig Lichtblau, Jose I. Iparraguirre
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Patent number: 8409557Abstract: The present invention is directed towards various topical protective formulations, which may be used as an adjunct in preventing the spread of a broad range of sexually transmitted diseases. The product is intended to be used as a topical lotion, cream, emulsion, or the like. The film forming excipients and active ingredients in the following formulations have demonstrated unique skin protective barrier properties with enhanced persistence that inhibits transmission of sexually transmitted diseases.Type: GrantFiled: March 26, 2012Date of Patent: April 2, 2013Assignee: CLJI IP Company, LLCInventors: Craig Lichtblau, Jose I. Iparraguirre
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Patent number: 8409552Abstract: The use of specific compounds of the Formula 1 (and also corresponding mixtures) in particular as cosmetic agents for the inhibition of the substance P-induced release of histamine from mast cells is described.Type: GrantFiled: June 15, 2012Date of Patent: April 2, 2013Assignee: Symrise AGInventors: Gerhard Schmaus, Holger Joppe, Martina Herrmann, Christopher Sabater-Luntzel, Tobias Vössing
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Patent number: 8383686Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.Type: GrantFiled: September 1, 2011Date of Patent: February 26, 2013Assignee: Ecolab USA Inc.Inventors: Joseph R. Wegner, Cheryl A. Littau
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Patent number: 8357392Abstract: A personal skin cleansing wipe comprising a flexible substantially dry matrix formed from synthetic, woven, non-woven or knitted fibers impregnated with a substantially anhydrous antimicrobial, antiseptic, antifungal solution in an amount wherein the matrix retains its substantially dry characteristics and the treatment solution includes an amount of PVP-iodine as active in solution in glycol and or glycerin. The treatment solution, in addition to an effective amount of PVP-iodine as active, contains surfactants, preferably Tego® Betaine CK D, and optionally a compatible fragrance and/or moisturizer. The wipe is activated with water just prior to use.Type: GrantFiled: November 16, 2011Date of Patent: January 22, 2013Inventors: Albert R Kelly, Lowell Safertein
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Publication number: 20120328683Abstract: The present application relates to oligomeric antimicrobial compounds and compositions comprising the same. The oligomers are formed by polymerizing aminoalkyl (meth)acrylate or aminoalkyl (meth)acrylamide monomer(s). In addition to imparting materials with broad spectrum antimicrobial activity, the oligomers can impart antimicrobial activity to substrates such as hair and skin.Type: ApplicationFiled: June 20, 2012Publication date: December 27, 2012Inventors: Zhiqiang Song, Ted Deisenroth
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Publication number: 20120301422Abstract: The invention provides a method of enhancing the action of a pharmaceutical agent selected from the group consisting of the anti-infective agents, the group comprising of the antimicrobial agents, the anthelmintic agents and the anti-ectoparasitic agents, but excluding coal tar solution and H1-antagonist antihistamines, and from the group consisting of the CPNS agents selected from the group of compounds acting on the central or peripheral nervous system, but excluding coal tar solution and H1-antagonist antihistamines and also excluding anti-inflammatory, analgesic and antipyretic agents and also provides an enhanced method for the administration of a nucleic acid substance to the cells of an animal, a plant or a micro-organism.Type: ApplicationFiled: January 16, 2003Publication date: November 29, 2012Inventor: Petrus Johannes Meyer
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Publication number: 20120294920Abstract: The invention relates to a wound dressing having a backing and an antimicrobial wound contact layer, wherein the wound contact layer has a hydrophobized active ingredient.Type: ApplicationFiled: May 16, 2012Publication date: November 22, 2012Applicant: Lohmann & Rauscher GmbH & Co. KGInventor: Marius-Thomas Gorka
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Patent number: 8313758Abstract: This invention relates to a method of producing and dispensing a foam using a “high lower alcohol content”(>40% v/v of a C1-4 alcohol) liquid composition. The liquid compositions comprise an alcohol, C1-4(>40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.Type: GrantFiled: June 4, 2007Date of Patent: November 20, 2012Assignee: Deb Worldwide Healthcare Inc.Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
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Patent number: 8309111Abstract: This invention relates to a “high lower alcohol content” (>40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise a C1-4 alcohol, (>40% v/v), a silicone-based surfactant of at least 0.001% by weight for foaming to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.Type: GrantFiled: September 14, 2006Date of Patent: November 13, 2012Assignee: Deb Worldwide Healthcare Inc.Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
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Patent number: 8263098Abstract: This invention relates to a “high lower alcohol content” (>40% v/v of a C1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise an alcohol, C1-4 (>40% v/v), a silicone-based surfactant of at least 0.001% by weight to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.Type: GrantFiled: March 7, 2006Date of Patent: September 11, 2012Assignee: Deb Worldwide Healthcare Inc.Inventors: Maria Teresa Fernandez de Castro, Bruce Michael Koivisto, Francisco Munoz
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Patent number: 8263666Abstract: Composition for topical application in the form of an oil-in-water emulsion containing an oily phase dispersed in an aqueous phase, and a hydrophilic polymer, the composition further containing (1) at least one elastomeric organopolysiloxane and (2) at least one lipophilic compound chosen from lipophilic amino acid compounds and lipophilic salicylic acid compounds. Uses thereof, including topical application to the skin, lips, hair, etc. Stabilization of certain emulsions using a lipophilic compound.Type: GrantFiled: October 16, 2003Date of Patent: September 11, 2012Assignee: L'OrealInventors: Christine Noel, Anne-France Livernette
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Publication number: 20120177725Abstract: The present invention relates to liposomal pharmaceutical preparations which include active agents such as antiseptic agents, wound-healing agents, or combinations thereof, useful in the treatment of external wounds. The active agents are encapsulated in liposomes, and the liposomes are incorporated in pharmaceutical preparations such as liquids, ointments, gels, lotions, or creams capable of delivering the active agents to external wound sites. The invention further relates to methods of preparation of the liposomes and the pharmaceutical preparations, and to methods of treatment of external wounds and ophthalmic infections.Type: ApplicationFiled: March 9, 2012Publication date: July 12, 2012Inventors: Dieter Ruckert, Hermann Gumbel, Wolfgang Fleischer, Karen Reimer, Horst Winkler
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Publication number: 20120148520Abstract: The present inventions relate to a number of fields including wound healing, a waterless antibacterial disinfectant, a surgical scrub, insect repellant, and methods of treating traumatic injuries, particularly those on the battlefield where there is a need to stabilize the patient and prevent infection.Type: ApplicationFiled: December 9, 2011Publication date: June 14, 2012Inventors: Michael Strobel, Gene Komer
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Publication number: 20120141396Abstract: An alcohol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer.Type: ApplicationFiled: December 30, 2011Publication date: June 7, 2012Applicant: QUICK-MED TECHNOLOGIES, INC.Inventors: William Toreki, Gerald Olderman
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Publication number: 20120134951Abstract: Provided according to some embodiments of the invention are topical gels that may release nitric oxide. Also provided are methods of using such topical gels in the treatment of wounds and other skin ailments. The topical gels comprise diazeniutndiolate-functionalized polysiloxane macromolecules.Type: ApplicationFiled: August 20, 2010Publication date: May 31, 2012Inventors: Nathan Stasko, Susanne Bauman, Pranav R. Joshi
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Patent number: 8173157Abstract: A pharmaceutical composition comprising a phenylamidine derivative or a salt thereof, represented by a general formula, wherein R1 and R2 may be same or different, and represent an optionally substituted C3-4alkyl group; and one or more agents selected from azole antifungal agents, polyene antifungal agents, candin antifungal agents and fluoropyrimidine antifungal agents, and a method for combination use of the phenylamidine derivative or a salt thereof and the agents are useful for treating fungal infections caused by a fungal pathogen.Type: GrantFiled: October 3, 2007Date of Patent: May 8, 2012Assignee: Toyama Chemical Co., Ltd.Inventor: Hiroshi Nishikawa
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Publication number: 20120055510Abstract: A personal skin cleansing wipe comprising a flexible substantially dry matrix formed from synthetic, woven, non-woven or knitted fibers impregnated with a substantially anhydrous antimicrobial, antiseptic, antifungal solution in an amount wherein the matrix retains its substantially dry characteristics and the treatment solution includes an amount of PVP-iodine as active in solution in glycol and or glycerin. The treatment solution, in addition to an effective amount of PVP-iodine as active, contains surfactants, preferably Tego® Betaine CK D, and optionally a compatible fragrance and/or moisturizer. The wipe is activated with water just prior to use.Type: ApplicationFiled: November 16, 2011Publication date: March 8, 2012Inventors: Albert R. Kelly, Lowell Safertein
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Patent number: 8119106Abstract: The present invention is related to a foamable composition of matter comprising iodine, water, a foam adjuvant, a surface-active agent and a gelling agent. This foamable composition, which may be provided in a propellant free foaming device, or alternatively may further comprise a propellant, evolves into foam, which is effective in the topical treatment and prevention of various skin disorders.Type: GrantFiled: July 8, 2009Date of Patent: February 21, 2012Assignee: Foamix LtdInventors: Dov Tamarkin, Doron Friedman, Meir Eini
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Patent number: 8101163Abstract: The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-30 fatty alcohol, monoglyceride or the reaction products thereof.Type: GrantFiled: December 3, 2009Date of Patent: January 24, 2012Assignee: Microdermis CorporationInventor: Griscom Bettle, III
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Publication number: 20120003174Abstract: Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.Type: ApplicationFiled: September 16, 2011Publication date: January 5, 2012Applicant: Foresight Biotherapeutics, Inc.Inventors: Joseph A. Capriotti, Bo Liang, C. Michael Samson, Jason Stein, Michael Weiser
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Patent number: 8062631Abstract: The present invention is directed towards various topical protective formulations which may be used as an adjunct in preventing the spread of a broad range of sexually transmitted diseases. The product is intended to be used as a topical lotion, cream, emulsion, or the like. The film forming excipients and active ingredients in the following formulations have demonstrated unique skin protective barrier properties with enhanced persistence that inhibits transmission of sexually transmitted diseases.Type: GrantFiled: February 27, 2008Date of Patent: November 22, 2011Assignee: CLJI I.P. Company, LLCInventors: Craig Lichtblau, Jose I. Iparraguirre
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Patent number: 8058315Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.Type: GrantFiled: May 26, 2010Date of Patent: November 15, 2011Assignee: Ecolab USA Inc.Inventors: Joseph R. Wegner, Cheryl A. Littau
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Publication number: 20110117048Abstract: Composition for application to skin comprising a biocide or combination of biocides (such as chlorhexidine, halogenated phenols, quaternary ammonium compounds; povidone-iodine; zinc pyridinethione; alcohols etc.) and at least one transcutaneous vehicle (for example alkyl methyl sulfoxides, alkyl pyrrolidones, glycols, glycol ethers and glycol esters) effective to convey the biocide to a sub epidermal “resident” micro-organism. Also a method for preparing a patient for surgery comprising the step of treating an area of the patient's skin at, and in the surrounding the vicinity of, the site of an intended surgical incision with a composition effective to kill more than 93% of both “transient” and “resident” micro-organisms.Type: ApplicationFiled: January 20, 2011Publication date: May 19, 2011Applicant: Novapharm Research (Australia) Pty Ltd.Inventor: Steven Kritzler
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Patent number: 7906138Abstract: Described is an intra-mammary teat sealant and a corresponding method of forming a physical barrier in the teat canal of a non-human animal for prophylactic treatment of mammary disorders during the animal's dry period. The method includes the step of infusing a bismuth-free teat seal formulation into the teat canal of the animal. The method also prevents the formation of black spot defect in dairy products, especially cheddar cheese, made from the milk of animals so treated.Type: GrantFiled: October 10, 2007Date of Patent: March 15, 2011Assignee: Wisconsin Alumni Research FoundationInventor: Scott A. Rankin
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Publication number: 20110038919Abstract: Textile materials for management of skin health complications associated with skin folds, as well as adhesives for attaching the materials to the skin of a subject. The adhesive can be supplied separately from the material, for application post-production, or can be applied to the material during production.Type: ApplicationFiled: January 27, 2009Publication date: February 17, 2011Applicant: COLOPLAST A/SInventors: Kevin C. Tauer, Charles E. Boyer
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Patent number: 7842725Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.Type: GrantFiled: July 24, 2008Date of Patent: November 30, 2010Assignee: Ecolab USA, Inc.Inventors: Joseph R. Wegner, Cheryl A. Littau
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Patent number: 7833542Abstract: A method and composition for treating healed wounds including hypertrophic scars so as to prevent scarring or reduce the size and improve the appearance of scars comprises applying to the healed wound or scar a composition comprising a fluid, film-forming carrier which may contain one or more active topical ingredients, the carrier hardening to a solid, tangible, membrane juxtaposed to the skin. Novel compositions using the film-forming carrier are also useful to treat a variety of adverse skin disorders, and internal physiological conditions.Type: GrantFiled: April 21, 2004Date of Patent: November 16, 2010Inventor: Joel R. Studin
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Patent number: 7829073Abstract: The present disclosure relates to anhydrous compositions for making up or caring for the skin, for example foundations, comprising at least one liquid organic phase comprising at least one non-volatile oil, at least one amorphous gelling polymer formed by polymerization of an olefin, and poly(methyl methacrylate) particles, wherein the amount of the at least one non-volatile oil present in the composition is greater than the amount of poly(methyl methacrylate) particles present in the composition. The compositions may exhibit a smooth and melting creamy texture, spread easily over the skin, and make it possible to obtain a homogeneous make-up that has a powdery and matt finish and that confers a pleasant softness on the skin. The make-up may also exhibit good properties of hold.Type: GrantFiled: April 6, 2005Date of Patent: November 9, 2010Assignee: L'Oreal S.A.Inventors: Guenaelle Martin, Agnès Themens
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Patent number: 7807780Abstract: Compositions and methods are provided that are useful for the delivery of therapeutic agents, including nucleic acids. The compositions can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.Type: GrantFiled: July 20, 2001Date of Patent: October 5, 2010Assignee: Revance Therapeutics, Inc.Inventors: Jacob Waugh, Michael Dake
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Publication number: 20100239519Abstract: This invention provides a composition for sterilization comprising povidone iodine in which by improving the persistence and stability of foam, the composition for sterilization is capable of preventing dripping in use as well as of achieving reliable disinfection and sterilization. The composition for sterilization in this invention is capable of forming stable and persistent foam as well as of achieving effective disinfection and sterilization by blending a specific amount of a sulfate type surfactant therein.Type: ApplicationFiled: October 30, 2008Publication date: September 23, 2010Applicant: MUNDIPHARMA INTERNATIONAL LIMITEDInventors: Udagawa Chikako, Kono Yoshie, Okamoto Takako
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Publication number: 20100234766Abstract: A method for enlarging a peripheral vein so as to facilitate venipuncture of the vein by topically applying a vasodilator salt compound to skin overlying the vein and permitting the salt compound to cause the vein to enlarge by causing the vein to fill with blood.Type: ApplicationFiled: May 19, 2010Publication date: September 16, 2010Inventor: R. Kent Hermsmeyer
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Publication number: 20100211010Abstract: Embodiments of the present invention provide a topical anesthetic and antiseptic dispensing device article of manufacture. In an embodiment of the invention, the article of manufacture includes a penetrating instrument including an elongated body with first and second distal end such that at least one of the distal ends includes a penetrating edge. By way of example, the penetrating instrument can be a syringe, an IV catheter needle assembly, a pressurized tube holder configured with a needle for blood draw, or a scalpel, to name a few possibilities. The article of manufacture also includes a container coupled to the elongated body of the penetrating instrument. The container provides at least one chamber. Finally, the article of manufacture includes a nozzle connected to the container and configured to dispense pressurized content of the container responsive to activating a trigger communicating with the nozzle.Type: ApplicationFiled: February 18, 2009Publication date: August 19, 2010Inventor: Michael Wycoki
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Publication number: 20100203005Abstract: The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-30 fatty alcohol, monoglyceride or the reaction products thereof.Type: ApplicationFiled: December 3, 2009Publication date: August 12, 2010Applicant: DRS. SOLUTIONS, LLCInventor: Griscom Bettle, III
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Patent number: 7749488Abstract: The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelf-life of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics.Type: GrantFiled: February 7, 2006Date of Patent: July 6, 2010Assignee: Stiefel Research Australia Pty LtdInventors: Albert Zorko Abram, Lilian Fuchshuber
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Publication number: 20100166694Abstract: The present invention relates to a method of determining the microbial bioburden in a wound (in particular a diabetic ulcer) in a test subject, the method comprising the step of measuring the level of a cytokine in a wound sample, wherein a cytokine level lower than a reference level indicates a significant microbial bioburden in the wound (or a cytokine level higher than a reference level indicates an insignificant microbial bioburden in the wound). The invention provides methods of diagnosis, prognosis and treatment of wound infection, and devices and kits for use in such methods.Type: ApplicationFiled: March 31, 2008Publication date: July 1, 2010Applicant: Ethicon ,Inc.Inventors: Philip Stephens, Ryan Moseley, Rachael Clark, Breda Mary Cullen
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Patent number: 7731983Abstract: A method and composition for treating healed wounds including hypertrophic scars so as to prevent scarring or reduce the size and improve the appearance of scars comprises applying to the healed wound or scar a composition comprising a fluid, film-forming carrier which may contain one or more active topical ingredients, the carrier hardening to a solid, tangible, membrane juxtaposed to the skin. Novel compositions using the film-forming carrier are also useful to treat a variety of adverse skin disorders, and internal physiological conditions.Type: GrantFiled: April 21, 2004Date of Patent: June 8, 2010Inventor: Joel R. Studin
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Patent number: 7682623Abstract: A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.Type: GrantFiled: December 5, 2005Date of Patent: March 23, 2010Assignee: Foamix Ltd.Inventors: Meir Eini, Dov Tamarkin
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Publication number: 20090304776Abstract: Described herein is a transmucosal delivery device and their use for delivering bioactive agents across a mucosal membrane. The delivery devices contain a pharmaceutically acceptable oxidizing and agents that facilitates the delivery of the blood stream across the mucosal membrane.Type: ApplicationFiled: December 19, 2008Publication date: December 10, 2009Inventors: Totada Shantha, Jessica Shantha, Erica Shantha, Lauren Shantha
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Publication number: 20090263345Abstract: Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.Type: ApplicationFiled: February 27, 2009Publication date: October 22, 2009Applicant: Foresight Biotherapeutics, Inc.Inventors: Joseph A. Capriotti, Bo Liang, C. Michael Samson, Jason Stein, Michael Weiser
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Patent number: 7604797Abstract: The present invention provides compositions and methods for treating burns comprising administering to a burn area of a subject in need thereof of a therapeutically effective amount of a composition comprising an anti-cytokine or anti-inflammatory agent or a functional derivative thereof; and a pharmaceutically acceptable excipient.Type: GrantFiled: December 16, 2004Date of Patent: October 20, 2009Assignee: BioMechanisms Inc.Inventor: Terry Lee Hicks
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Publication number: 20090246165Abstract: An alcohol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer.Type: ApplicationFiled: August 22, 2006Publication date: October 1, 2009Applicant: QUICK-MED TECHNOLOGIES, INC.Inventors: William Toreki, Gerald Olderman
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Patent number: 7566460Abstract: A hydroalcoholic lotion is disclosed which comprises (a) a lower alcohol and water in a weight ratio of about 35:65 to 100:0, and (b) between at least 0.5% and 8% by weight thickener system comprised of at least one emulsifier present in at least 0.05% by weight wherein the composition in a polymer free state has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein the emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The hydroalcoholic composition is useful as a hand preparation such as a lotion or as a presurgical scrub replacement.Type: GrantFiled: July 25, 2006Date of Patent: July 28, 2009Assignee: 3M Innovative Properties CompanyInventors: Robert A. Asmus, Matthew T. Scholz, Jill R. Charpentier
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Publication number: 20090148394Abstract: The invention provides a method of treating a wound (for example, a chronic ulcerous skin lesion) in a human or non-human mammal (particularly a human). The wound is contacted with a topical hydrogel composition comprising a hydrophilic polymer carrying multiple pendant sulphonyl groups, optionally with multiple pendant carboxylic groups, on each polymer molecule.Type: ApplicationFiled: July 14, 2006Publication date: June 11, 2009Inventor: Hugh Semple Munro
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Patent number: RE40882Abstract: The present invention can be used in pharmacology specifically in the preparation of interferon-containing compositions, which are capable of conserving their biological activity and can be administered intranasally, e.g. in the preparation of nasal drops. This invention essentially refers to an antiviral agent in the form of nasal drops that contains a genetically engineered alpha, beta or gamma interferon with a viscosity of (1.1?30.0)* 10 10?3 Pascal .second, a biocompatible polymer and a buffer mixture. The agent may further include an antioxidant, and the ingredients are contained in the following amounts per ml buffer mixture: 1,000 to 5,000 500,000 IU of genetically engineered interferon; 0.005 to 0.714 g of biocompatible polymer; and 0.0001 to 0.0008 g of an antioxidant. TRILON B® (disodium salt of EDTA) is used as the antioxidant, whereas polyvinylpyrrolidone and/or polyethylene oxide is (are) used as the biocompatible polymer(s) at polyvinylpyrrolidone/polyethylene oxide ratio of 1:1-50.Type: GrantFiled: September 6, 1999Date of Patent: August 25, 2009Inventors: Petr Jakovlevich Gaponyuk, Elena Alexeevna Markova, Iliya Alexandrovich Markov
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Patent number: RE41279Abstract: The mastitis control teat dip composition having a visible indicator aspect of the invention provides a softening, soothing, smoothing, relaxing property, a rapid initial kill, a useful highly pseudoplastic rheology, a barrier/film-forming capacity, a unique antimicrobial composition that is stable over an extended period of time, and unexpected long term microbial control when compared to the prior art materials disclosed in patents and used in the marketplace. The indicator aspect provides ease of visually detecting the material on the animal skin and can indicate efficacy of the material. The compositions of the invention are made by combining an aqueous liquid composition containing the visual indicator combined with the organic components which can be combined with a simple aqueous solution of a salt of chlorous acid, preferably an alkali metal chlorite.Type: GrantFiled: March 2, 2006Date of Patent: April 27, 2010Assignee: Ecolab Inc.Inventors: David D. McSherry, Francis L. Richter