Polymer From Ethylenic Monomers Only Patents (Class 424/78.31)
-
Patent number: 8796476Abstract: Pest controlling compositions exhibiting enhanced pesticidal activity levels and methods for preparing the same are disclosed. In one embodiment, a method includes providing a liquid composition that includes at least one pesticide and at least one co-ingredient that enhances pesticidal activity of the composition compared to a composition dissimilar only in not having the at least one co-ingredient. The at least one co-ingredient may include at least one metal oxide, a combination of at least one transition metal salt and at least one proteinaceous material or a combination of at least one proteinaceous material and at least one polymeric material. The method further includes spray drying the liquid composition to provide a solid composition. In one aspect of this embodiment, the solid composition provided by the spray drying exhibits enhanced pesticidal activity compared to the liquid composition.Type: GrantFiled: April 27, 2010Date of Patent: August 5, 2014Assignee: Dow AgroSciences, LLCInventors: Stephen L. Wilson, Lei Liu, James D. Thomas, Raymond E. Boucher, Jr., James E. Dripps, Margaret S. Kempe, Martin C. Logan, Douglas J. Linscott, John M. Atkinson
-
Publication number: 20140212373Abstract: A multi-vinylsulfone containing molecule is described herein. The multi-vinylsulfone containing molecule can be formed by dissolving a water soluble polymer containing a hydroxyl group in an aqueous solution to form a polymer solution; adding a molecule containing two vinylsulfone groups to the polymer solution; and forming a modified polymer by controlling a number of the vinylsulfone groups that are added to the polymer. A hydrogel is also described herein that can include the multi-vinylsulfone containing molecule and a multi-thiol containing molecule. The hydrogel can be formed from an aqueous solution that includes the multi-vinylsulfone containing molecule and the multi-thiol containing molecule by undergoing gelatation upon delivery to a site in the body. Also described is a drug delivery system that employs the hydrogel.Type: ApplicationFiled: June 15, 2012Publication date: July 31, 2014Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Ying Chau, Yu Yu
-
Patent number: 8784793Abstract: A biological coating material that includes a polymerizable polyacrylate monomer; a volatile liquid; a polymer selected from a synthetic rubber, a natural rubber, and a thermoplastic elastomer. The biological liquid coating material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.Type: GrantFiled: July 22, 2013Date of Patent: July 22, 2014Assignee: Rochal Industries, LLPInventors: Ann Beal Salamone, Joseph C. Salamone
-
Patent number: 8784791Abstract: A method is provided for preparing water-soluble polymer derivatives bearing a terminal N-succinimidyl ester. The method involves the hydrolyzing an ortho ester of a water-soluble polymer so as provide the corresponding acid and subsequently esterifying the acid.Type: GrantFiled: April 4, 2013Date of Patent: July 22, 2014Assignee: Nektar TherapeuticsInventor: Antoni Kozlowski
-
Patent number: 8784849Abstract: Isolatable, hydroxyapatite-targeting polymeric structures, and biologically active conjugates thereof, are provided. The polymeric structure includes a linear or branched water-soluble and non-peptidic polymer backbone, such as a PEG backbone, having at least two termini, a first terminus being covalently bonded to a hydroxyapatite-targeting moiety, such as a bisphosphonate, and a second terminus covalently bonded to a chemically reactive group, wherein said chemically reactive group is protected or unprotected. Methods of preparing and using hydroxyapatite-targeting polymeric structures, and biologically active conjugates thereof, are also provided.Type: GrantFiled: February 11, 2013Date of Patent: July 22, 2014Assignee: Nektar TherapeuticsInventors: Michael J. Roberts, Antoni Kozlowski
-
Publication number: 20140199376Abstract: Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.Type: ApplicationFiled: February 20, 2014Publication date: July 17, 2014Applicant: NanoPharmaceuticals LLCInventors: Shaker A. Mousa, Faith B. Davis, Paul J. Davis
-
Publication number: 20140186416Abstract: A method for repairing or replacing damaged tissue, or for providing post-surgical augmentation, comprising administering a pliable biocompatible material and a physiologically acceptable suspending agent to a patient is disclosed. Copolymers of unsubstituted acrylate and substituted acrylate are disclosed as pliable biocompatible materials.Type: ApplicationFiled: March 7, 2014Publication date: July 3, 2014Inventor: Ayman BOUTROS
-
Publication number: 20140186290Abstract: There are provided compositions and methods to disperse mucin and/or actin using nanoparticles wherein the average diameter of the nanoparticles is less than about 1000 nm.Type: ApplicationFiled: March 7, 2014Publication date: July 3, 2014Applicant: The Regents of the University of CaliforniaInventors: Wei-Chun Chin, Eric Yi-Tong Chen, Yung-Chen Wang
-
Publication number: 20140178328Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.Type: ApplicationFiled: February 28, 2014Publication date: June 26, 2014Applicant: 206 ORTHO, Inc.Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
-
Publication number: 20140178465Abstract: A method for protection of tissues subject to ischemic and/or reperfusion damage is provided. The method includes administering to the tissue a composition comprising nanodevices. The nanodevices can take the form of, for example, polymeric nanoparticles or lipidic nanoparticles. The nanodevices also find use in methods for reducing ischemic injury in tissue at risk of such injury, such as heart and brain tissue.Type: ApplicationFiled: February 28, 2014Publication date: June 26, 2014Applicants: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, JOHNS HOPKINS UNIVERSITYInventors: Corinne Bright, Rachel Bright, Eric Churchill, Kam W. Leong, Daria Mochly-Rosen
-
Patent number: 8758738Abstract: The present invention relates to compositions of cyanoacrylate monomer, a method of improving the viscosity and the curing speed with a single additive and a process of providing sterilized cyanoacrylate adhesive compositions for application in the medical field.Type: GrantFiled: November 1, 2013Date of Patent: June 24, 2014Assignee: Adhezion Biomedical, LLCInventors: Sheng Zhang, Rafael Ruiz, Sr.
-
Patent number: 8753620Abstract: According to an aspect of the invention, injectable bulking compositions are provided which contain the following: (a) fibers that are configured to prevent migration to locations in the body remote from the injection site, for example, because they have a minimum length that is sufficiently large to prevent migration of the fibers and/or because they have surface features that stimulate host tissue response to lock the fibers in position and (b) a carrier in an amount effective to render the composition injectable.Type: GrantFiled: August 16, 2012Date of Patent: June 17, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: Jianmin Li, Michael Madden
-
Publication number: 20140140948Abstract: The present invention relates to a method of pre-rinsing laundry and treating other surfaces employing a composition that can kill bedbug eggs. The composition includes an anionic compound and is at pH just above neutral, e.g., about 7 to about 9.Type: ApplicationFiled: November 20, 2012Publication date: May 22, 2014Applicant: Ecolab USA Inc.Inventors: Kim R. Smith, Erik Olson, Yvonne Killeen, Victor Man, Joelle Olson, Erin Loosbrock
-
Patent number: 8715635Abstract: A rotaxane consisting of a cucurbituril and an uncharged guest molecule, having low or null affinity therebetween is provided as well as processes for providing the same. Various uses as energy converters (“frictionless” molecular motors), biochips and biosensors using the same are also provided.Type: GrantFiled: February 6, 2008Date of Patent: May 6, 2014Assignee: Technion Research & Development Foundation LimitedInventor: Ehud Keinan
-
Patent number: 8715708Abstract: A novel class of Cylic Acetal biomaterials (CABs) based on a cyclic acetal unit is disclosed and claimed by Applicants. Two novel biomaterials suitable for use in a variety of biological applications including in the orthopedic field for joint and cartilage replacement and/or repair, and bone cement. The biomaterials are comprised of either a network of monomers of 5-ethyl-5-(hydroxymethyl)-?,?-dimethyl-1,3-dioxane-2-ethanol diacrylate (EHD) and a hydrogel comprised of EHD and poly(ethylene glycol) diacrylate (PEG-EHD).Type: GrantFiled: August 31, 2006Date of Patent: May 6, 2014Assignee: University of MarylandInventors: John Patrick Fisher, Sachiko Kaihara, Jennifer Lynn Moreau, Parth Modi
-
Patent number: 8709395Abstract: A method for repairing or replacing damaged tissue, or for providing post-surgical augmentation, comprising administering a pliable biocompatible material and a physiologically acceptable suspending agent to a patient is disclosed. Copolymers of unsubstituted acrylate and substituted acrylate are disclosed as pliable biocompatible materials.Type: GrantFiled: December 23, 2011Date of Patent: April 29, 2014Inventor: Ayman Boutros
-
Patent number: 8703113Abstract: Side-chain crystallizable (SCC) polymers are useful in various medical applications. In certain applications, heavy atom containing side-chain crystallizable polymers (HACSCCP's) are particularly useful. An example of a HACSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. In certain configurations, the heavy atoms are present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes an HACSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product. A polymeric material that includes a SCC polymer may also be fabricated into other medical devices, such as stents.Type: GrantFiled: January 18, 2006Date of Patent: April 22, 2014Assignee: REVA Medical Inc.Inventors: Donald K. Brandom, James E. McGrath, Joan Zeltinger, Eric V. Schmid, Robert K. Schultz
-
Publication number: 20140105950Abstract: The present invention relates to a haemostatic material comprising a haemostat agent and a bioadhesive agent. Such a haemostatic material is useful, for example, in effectively controlling bleeding with a reduced compression period compared to the guidance of a minimum of three minutes compression using a haemostatic bandage.Type: ApplicationFiled: March 12, 2012Publication date: April 17, 2014Applicant: MEDTRADE PRODUCTS LIMITEDInventors: Craig Hardv, Guy Eason, Andrew Hoggarth
-
Patent number: 8697769Abstract: A transparent lacquer composition that can be used as a protective and gloss lacquer for surface coating is described. The lacquer composition can be a dental material and a method for preparing a lacquer composition is also described. Also described are novel polymerizable monomers comprising at least one polyalicyclic structure element and certain ethylenic structure elements that are particularly suitable for use in a lacquer composition.Type: GrantFiled: September 29, 2011Date of Patent: April 15, 2014Assignee: VOCO GmbHInventors: Tobias Blömker, Manfred Stepputtis, Reinhard Maletz, Manfred Thomas Plaumann
-
Patent number: 8679537Abstract: Methods for sealing an orifice in tissue in the body of a living animal using an adhesive formed by reacting an oxidized polysaccharide with a poly(hydroxylic) compound derivatized with acetoacetate groups in the presence of a base catalyst are disclosed. Methods for using the adhesive for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; and drug delivery are described.Type: GrantFiled: August 24, 2006Date of Patent: March 25, 2014Assignee: Actamaz Surgical Materials, LLCInventor: Samuel David Arthur
-
Patent number: 8679536Abstract: Adhesives formed by reacting an oxidized polysaccharide with a poly(hydroxylic) compound derivatized with acetoacetate groups in the presence of a base catalyst are disclosed. The use of the adhesives for medical and veterinary applications such as topical wound closure; and surgical procedures, such as intestinal anastomosis, vascular anastomosis, tissue repair, and ophthalmic procedures; and drug delivery are described. The adhesive may also be used for industrial and consumer applications.Type: GrantFiled: August 24, 2006Date of Patent: March 25, 2014Assignee: Actamax Surgical Materials, LLCInventor: Samuel David Arthur
-
Publication number: 20140072603Abstract: The present invention relates to biomaterials that interact with and regulate immune functions, as well as implantable materials and devices. In one embodiment, the present invention provides an implantable medical device comprising a biomaterial coated with one or more CD200 molecules. In another embodiment, the present invention provides a method of treating inflammation by administering a composition comprising one or more biomaterials that inhibit immune reactivity.Type: ApplicationFiled: September 12, 2013Publication date: March 13, 2014Applicant: The Regents of the University of CaliforniaInventors: Wendy Liu, Yoon Kyung Kim
-
Publication number: 20140072518Abstract: The present disclosure is directed to a class of fluorinated copolymers, such as a PTFE copolymers, that can be dissolved in low toxicity solvents, such as Class III Solvents, and that enable the creation of stable water-in-solvent emulsions comprising the fluorinated copolymers dissolved in a low toxicity solvents and a hydrophilic agent (e.g., a therapeutic agent) dissolved in an aqueous solvent, such as water or saline.Type: ApplicationFiled: September 12, 2013Publication date: March 13, 2014Applicant: W. L. Gore & Associates, Inc.Inventors: Robert L. Cleek, Paul D. Drumheller, Theresa A. Holland
-
Publication number: 20140072636Abstract: The invention relates to bulking agents and apparatus and methods for using the disclosed bulking agents. The bulking agents can be used to treat such conditions as urinary and fecal incontinence, gastro-esophageal reflux, ancurismal blockages, and cosmetic deformities. The invention also relates to an injection method that reduces the injection pressure required to place the bulking agents.Type: ApplicationFiled: November 18, 2013Publication date: March 13, 2014Applicant: Boston Scientific Scimed, Inc.Inventors: George Bourne, Michael Madden, Arthur R. Madenjian, Doreen Rao, Marcia Buiser, Jianmin Li, Raymond Rackley, Barry N. Gellman
-
Publication number: 20140065233Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.Type: ApplicationFiled: November 8, 2013Publication date: March 6, 2014Applicant: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
-
Patent number: 8658141Abstract: The present invention is directed to a method of making up keratinous substrates involving applying onto the keratinous substrate a composition containing a) a block copolymer, b) a tackifier, c) an alkyl silsesquioxane wax, d) a liquid fatty phase, and e) optionally, a colorant.Type: GrantFiled: January 10, 2008Date of Patent: February 25, 2014Assignee: L'OrealInventors: Hy Si Bui, Ann Marie Rohmeyer, Padraig McDermott
-
Publication number: 20140044670Abstract: Provided are therapeutic formulations and methods of use thereof.Type: ApplicationFiled: July 2, 2013Publication date: February 13, 2014Inventors: Betty Yu, Joseph Lomakin, Soo-Young Kang, Benjamin W. Adams
-
Patent number: 8647666Abstract: The invention provides a method of ameliorating systemic inflammation in a patient involving administering to the patient a therapeutically effective dose of composition including polystyrene divinyl benzene copolymer and a polyvinyl pyrrolidone polymer. More particularly, the method relates to using these polymers as an enteral sorbent preparation to remove inflammatory mediators, such as cytokines, from the intestinal lumen. The polymers can be in the form of a preparation of polystyrene divinyl benzene copolymer beads with a biocompatible polyvinyl pyrrolidone polymer coating.Type: GrantFiled: October 2, 2009Date of Patent: February 11, 2014Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: John A. Kellum, Mitchell P. Fink
-
Patent number: 8647614Abstract: A method for reducing the occurrence of new post-operative fractures in vertebrae of a patient's spine after a vertebroplasty procedure performed to stabilize a fracture in a vertebra of a patient comprising the steps of performing a vertebroplasty procedure to stabilize a fracture in a vertebra of the patient, wherein the vertebroplasty procedure comprises the step of injecting a material into the fractured vertebra, wherein the material is formed by mixing together a first paste and a second paste, wherein the first paste comprises at least one of a polymerizable monomer and a filler, and wherein the second paste comprises at least one of a polymerizable monomer and a filler.Type: GrantFiled: February 16, 2010Date of Patent: February 11, 2014Assignee: Orthovita, Inc.Inventors: Theodore D. Clineff, Maarten Persenaire, Gina M. Nagvajara, Marissa M. Darmoc, Matthew B. Havener, Stephen G. Gilbert, Erik M. Erbe
-
Publication number: 20140037574Abstract: The invention provides a pharmaceutical composition for oral administration of a pharmaceutically active agent to a subject, including the pharmaceutically active agent and an inhibitor of CYP3A4. Administration of the inhibitor and the pharmaceutically active agent reduces pre-systemic degradation of the pharmaceutically active agent by CYP3A4. The inhibitor can be poly(ethylene glycol), methoxy poly(ethylene glycol), aminated poly(ethylene glycol), O-(2-aminoethyl)-O-methoxy poly(ethylene glycol), polyoxyethylene glycol, branched poly(ethylene glycol), 3-arm poly(ethylene glycol), 4-arm poly(ethylene glycol), 8-arm-poly(ethylene glycol)polyamine, poly(L-lysine), poly(L-arginine), poly(L-alanine), poly(L-valine), poly(L-serine), poly(L-histidine), poly(L-isoleucine), poly(L-leucine), poly(L-glutamic acid), poly(L-glutamine), poly(L-guanidine), poly(methyl methacrylate), polyvinyl acetate, polyacrylate, poly(lactic-co-glycolic acid) and derivatives thereof. A method of treatment is also described.Type: ApplicationFiled: November 28, 2011Publication date: February 6, 2014Inventors: Pius Sedowhe Fasinu, Viness Pillay, Yahya Essop Choonara, Lisa Claire Du Toit
-
Patent number: 8632791Abstract: Provided are silicone microparticles including 100 parts by mass of silicone elastomer spherical microparticles having a volume average particle diameter within a range from 0.1 to 100 ?m, and 0.5 to 25 parts by mass of a polyorganosilsesquioxane that coats the surface of the silicone elastomer spherical microparticles, in which the silicone elastomer is capable of absorbing not less than 30 parts by mass of at least one oily substance selected from the group consisting of sebum, hydrocarbon oils and ester oils per 100 parts by mass of the silicone elastomer.Type: GrantFiled: October 30, 2009Date of Patent: January 21, 2014Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Yoshinori Inokuchi, Ryuji Horiguchi
-
Patent number: 8623413Abstract: The present invention is directed to medical devices and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid polymer having a melting point less than about 40° C., as determined by differential scanning calorimetry.Type: GrantFiled: December 7, 2007Date of Patent: January 7, 2014Assignee: Ethicon, Inc.Inventors: Aruna Nathan, Joel Rosenblatt, Steven C. Arnold
-
Publication number: 20130336916Abstract: The invention generally relates to environmental friendly pesticide compounds, formulations, methods of preparation and application and utilities thereof. More particularly, the invention relates to pesticide compounds and formulations that include terpenes or terpenoids having chemical formula of (C5H8)n, and its derivatives and analogs thereof, as active insecticidal ingredients; certain botanical essential oils as synergists, and other select ingredients as additives.Type: ApplicationFiled: June 18, 2012Publication date: December 19, 2013Inventor: Tao Zhong
-
Publication number: 20130323316Abstract: The present invention relates to elastic, hydrophilic and substantially spherical microspheres useful for dermal augmentation and tissue bulking. The invention provides injectable compositions comprising the microspheres and a biocompatible carrier for use in dermal augmentation. The present invention further provides methods of dermal augmentation and tissue bulking, particularly for the treatment of skin contour deficiencies, Gastro-esophageal reflux disease, urinary incontinence, and urinary reflux disease, using the injectable compositions.Type: ApplicationFiled: August 7, 2013Publication date: December 5, 2013Applicant: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
-
Publication number: 20130323317Abstract: The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The invention also relates to methods of tissue bulking, particularly for the treatment of Gastro-esophageal reflux disease, urinary incontinence, or urinary reflux disease, using the injectable compositions.Type: ApplicationFiled: August 8, 2013Publication date: December 5, 2013Applicant: Biosphere Medical, Inc.Inventors: Jean-Marie Vogel, Richard Thomas, Egisto Boschetti
-
Patent number: 8574604Abstract: The invention features polymers noncovalently complexed with a biologically active agent. The polymer complexes include at least one shielding moiety covalently tethered to at least one complexing moiety, which is complexed with at least one biologically active agent.Type: GrantFiled: April 14, 2006Date of Patent: November 5, 2013Assignee: Interface Biologics, Inc.Inventors: Roseita Esfand, Paul J. Santerre, Meilin Yang
-
Patent number: 8574558Abstract: A photopolymerizable composition for forming a cosmetic coating for natural and artificial nails of humans and animals comprising a photoinitiator and a (meth)acrylate monomer prepared by reacting a core polyol derived or functionalized from a renewable resource with an a (meth)acrylate monomer and coatings formed from such compositions under UV or other radiation.Type: GrantFiled: January 24, 2011Date of Patent: November 5, 2013Assignee: Mycone Dental Supply Co., Inc.Inventor: Lawrence W. Steffier
-
Patent number: 8557262Abstract: The present invention provides divinyl ether derivatives capable of releasing in a controlled manner at least one active aldehyde and/or ketone into the surrounding environment. The invention relates to the use of these divinyl ether derivatives as perfuming or flavoring ingredients, as well as to the perfuming compositions and consumer articles containing them.Type: GrantFiled: August 31, 2009Date of Patent: October 15, 2013Assignee: Firmenich SAInventors: Gary Bernard Womack, Robert Langley Fuller, Glenn Paul Johannes Verhovnik, Nathalie Pinel, Magali Lateulere, Marie Buy
-
Patent number: 8541013Abstract: The invention is directed to a copolymer comprising at least three types of monomeric units, said three types of monomeric units comprising: a temperature-sensitive unit, a hydrophilic unit, and a hydrophobic unit comprising at least one pH-sensitive moiety; wherein said hydrophobic monomeric unit is derived from a copolymerizable unsaturated fatty acid.Type: GrantFiled: November 19, 2007Date of Patent: September 24, 2013Assignee: Agency for Science, Technology and ResearchInventors: Yi Yan Yang, Kumaresh Soppimath
-
Patent number: 8530526Abstract: A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the composition are provided.Type: GrantFiled: September 2, 2010Date of Patent: September 10, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Stephen D. Pacetti
-
Patent number: 8530418Abstract: The invention is directed to novel cellular factor-containing solution compositions (referred to herein as “CFS” compositions), including novel sustained-release cellular factor-containing solution compositions (referred to herein as “SR-CFS” compositions), methods of making such novel compositions and uses thereof.Type: GrantFiled: October 17, 2012Date of Patent: September 10, 2013Assignee: Stemnion, Inc.Inventors: Vivienne S Marshall, Catherine J Trumpower, Charlotte Emig
-
Patent number: 8530553Abstract: A binder composition for spray used for interior materials is disclosed to provide glass wool or rock wool with an adhesive force by simultaneously spraying two solutions onto the glass wool or rock wool so that the glass wool or rock wool is adhered to steel or concrete to enhance effects of heat insulation and sound insulation. The binder composition contains a first solution of 200 to 400 parts by weight consisting of polyvinyl alcohol, preservative, antifoaming agent and purified water, and a second solution of 100 parts by weight consisting of boric acid, basic compound, glycerin and purified water.Type: GrantFiled: March 10, 2010Date of Patent: September 10, 2013Assignees: Daehyup Tech Co., Ltd, Daehyup Spray Co., Ltd, Hyung Sek ChoiInventors: Hyung Sek Choi, Jong Pil Hwang
-
Patent number: 8524215Abstract: An absorbable PEG-based hydrogel prepared from a multi-arm-PEG-vinylsulfone having about 3 to about 8 arms and a multi-arm-PEG-R-sulfhydryl having about 3 to about 8 arms; where R is defined as an ester linkage, such as carboxylate ester, lactate ester, and isobutyrate ester have been disclosed. Additionally, sustained release compositions that are prepared from an absorbable PEG-based hydrogel and a protein have been disclosed which provide sustained release of proteins and peptides.Type: GrantFiled: July 29, 2011Date of Patent: September 3, 2013Assignee: Janssen Biotech, Inc.Inventors: Chee-Youb Won, Helen Cui
-
Patent number: 8512757Abstract: The invention provides a block copolymer comprising at least a first block and a second block. The first block comprises a plurality of temperature-sensitive monomeric units, a plurality of hydrophilic monomeric units and a plurality of targeting monomeric units, and the second block comprises a plurality of hydrophobic monomeric units. The second block comprises at least one pH-sensitive moiety.Type: GrantFiled: July 5, 2006Date of Patent: August 20, 2013Assignee: Agency for Science, Techology and ResearchInventors: Yi-Yan Yang, Shao-Qiong Liu
-
Publication number: 20130195792Abstract: The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising administration of a therapeutically effective dose of a sorbent that sorbs an inflammatory mediator in said patient. In some preferred embodiments, the sorbent is a biocompatible organic polymer.Type: ApplicationFiled: April 1, 2011Publication date: August 1, 2013Applicant: CYTOSORBENTS CORPORATIONInventors: Phillip P. Chan, Wei-Tai Young, Vincent J. Capponi, Thomas D. Golobish, Robert H. Bartlett
-
Patent number: 8491881Abstract: A biological coating material that includes a polymerizable polyacrylate monomer; a volatile liquid; a polymer selected from a synthetic rubber, a natural rubber, and a thermoplastic elastomer. The biological liquid coating material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.Type: GrantFiled: April 30, 2012Date of Patent: July 23, 2013Assignee: Rochal Industries, LLPInventors: Ann Beal Salamone, Joseph C. Salamone
-
Publication number: 20130177524Abstract: The present invention provides methods for preventing the adverse effects of transfusing a patient with blood or blood products compromised by storage lesion. The methods include administering to a patient a pharmaceutical composition comprising an effective amount of a polyoxyethylene/polyoxypropylene copolymer and a pharmaceutically acceptable carrier. The safety and effectiveness of transfusing blood with storage lesion can be increased using the methods of the invention.Type: ApplicationFiled: March 1, 2013Publication date: July 11, 2013Applicant: Adventrx PharmaceuticalsInventor: Adventrx Pharmaceuticals
-
Patent number: 8475815Abstract: A composition comprising an alloplastic injectable suspension for use as a dermal filler comprising a biocompatible and pliable material and a physiologically acceptable suspending agent comprising particles of the unsubstituted acrylate/substituted acrylate copolymer with a diameter of less than about 100?. Methods for making a composition comprising an alloplastic injectable suspension for use as a dermal filler are provided. Methods of augmenting soft tissue to provide long-term reduction of a skin defect and the stimulation of collagen production are also provided.Type: GrantFiled: October 29, 2008Date of Patent: July 2, 2013Inventor: Ayman Boutros
-
Publication number: 20130156724Abstract: The invention describes for first time the activity of poloxamines as inducers in the differentiation of mesenchymal or progenitor cells. In particular, the invention demonstrates that poloxamines have an osteogenic ability. The invention relates to the use of one or more poloxamines or a pharmaceutical composition comprising same for the preparation of a drug for treting patients with bone defects in general. The invention also relates to a method for inducing the differentiation of mesenchymal or progenitor cells into osteoblasts by bringing said cells into contact with a sterilised aqueous dispersion or solution of one or more poloxamines.Type: ApplicationFiled: May 12, 2011Publication date: June 20, 2013Applicant: UNIVERSIDADE DE SANTIAGO DE COMPOSTELAInventors: Carmen Alvarez Lorenzo, Ana Rey Rico, Teresa Silva Rivera, José Couceiro Follente, Angel Concheiro Nine
-
Patent number: RE44578Abstract: Pharmaceutical compositions that have excellent storage stability even though they include a active component that is susceptible to degradation in an acidic environment are disclosed. The stabilized pharmaceutical composition of the invention includes a ring-opened 7-substituted-3,5-dihydroxyheptanoic or a ring-opened 7-substituted-3,5-dihydroxyheptenoic acid, or a pharmaceutically acceptable salt thereof, as an active component and a stabilizing effective amount of at least one amido-group containing polymeric compound or at least one amino-group containing polymeric compound, or combination thereof; wherein the stabilized pharmaceutical composition does not contain a stabilizing effective amount of another stabilizer or a combination of other stabilizers.Type: GrantFiled: September 18, 2009Date of Patent: November 5, 2013Assignee: TEVA Pharmaceutical Industries, Ltd.Inventors: Michael Fox, Ivo Dorossiev