Bacteria Or Actinomycetales Patents (Class 424/93.4)
Clostridium (Class 424/93.41)
Staphylococcus (Class 424/93.42)
Streptomyces (Class 424/93.43)
Streptococcus (Class 424/93.44)
Lactobacillus or pediococcus or leuconostoc (Class 424/93.45)
Bacillus (Class 424/93.46)
Pseudomonas (Class 424/93.47)
Enterobacteriaceae (Class 424/93.48)
  • Instant thickener comprising probiotics for hot or cold foods and beverages to be administered to dysphagic patients
    Patent number: 8691244
    Abstract: The present invention relates to the fields of hydration and nutrition for dysphagic patients. In particular, the present invention relates to thickeners comprising probiotic microorganisms and to compositions comprising such thickeners. The probiotic micro-organisms may be non-replicating probiotic micro-organisms such as bioactive heat treated probiotic microorganisms.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: April 8, 2014
    Assignee: Nestec S.A.
    Inventors: Annick Mercenier, Sophie Nutten, Guenolee Prioult
  • sp. nov. and use for control of insect pests
    Patent number: 8691219
    Abstract: Chromobacterium subtsugae sp. nov., a new species of the genus Chromobacterium which possesses insecticidal activity, is described. The invention also relates to insecticidally-active metabolites obtained from the strain and to insecticidal compositions comprising cultures of the strain and/or supernatants, filtrates, and extracts obtained from the strain, and use thereof to control insect pests.
    Type: Grant
    Filed: February 8, 2007
    Date of Patent: April 8, 2014
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Phyllis A. W. Martin, Ashaki D. S. Shropshire, Dawn E. Gundersen-Rindal, Michael B. Blackburn
  • Surfactant gas pressurized liquid composition and method and package for delivering
    Patent number: 8691301
    Abstract: A self gassing composition comprising at least one surfactant and a fermentation base including a gas producing organism and at least one sugar is disclosed. Use of a nonionic surfactant in the self gassing composition allows the fermentation base to continue reacting and producing gas. Additionally, a personal care cleansing product and method for storing and delivering an aqueous composition having at least one surfactant and pressurized gas dissolved therein is disclosed. In one aspect, the composition is stored in an internal reservoir in a container such that when a sealing device is removed from a valveless opening, the composition foams and plumes out the opening of the container as the gas dissolved in the composition is released. In addition to the self gassing composition, a pressurized gas may be injected into a surfactant composition to produce the gas pressurized cleaning composition.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: April 8, 2014
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Jeffery Richard Seidling, Scott W. Wenzel, Stacy Averic Mundschau, David W. Koenig
  • MODULATING BACTERIAL MAM POLYPEPTIDES IN PATHOGENIC DISEASE
    Publication number: 20140093477
    Abstract: The disclosure relates to methods and compositions for preventing or inhibiting pathogenic bacterial infections in a subject caused by pathogenic bacteria expressing a multivalent adhesion molecule (MAM) polypeptide by administering to a subject a composition comprising a MAM polypeptide or a non-pathogenic bacterium expressing a MAM polypeptide, or a combination thereof.
    Type: Application
    Filed: March 30, 2012
    Publication date: April 3, 2014
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Kim Orth, Hyeilin Ham, Anne-Marie Krachler
  • PROBIOTIC BACTERIAL STRAINS AND SYMBIOTIC COMPOSITION CONTAINING THE SAME INTENDED FOR INFANT FOOD
    Publication number: 20140093479
    Abstract: Selection of probiotic strains belonging to the genus Bifidobacterium and to a symbiotic composition containing the same for use of feeding infants, is described.
    Type: Application
    Filed: May 9, 2012
    Publication date: April 3, 2014
    Inventors: Giovanni Mogna, Gian Paolo Strozzi, Luca Mogna
  • GUT MICROBIOME AS A BIOMARKER AND THERAPEUTIC TARGET FOR TREATING OBESITY OR AN OBESITY RELATED DISORDER
    Publication number: 20140093478
    Abstract: The present invention relates to the gut microbiome as a biomarker and therapeutic target for energy harvesting, weight loss or gain, and/or obesity in a subject. In particular, the invention provides methods of altering and monitoring the relative abundance of Bacteroides and Firmicutes in the gut microbiome of a subject.
    Type: Application
    Filed: October 9, 2013
    Publication date: April 3, 2014
    Inventors: Peter J. Turnbaugh, Ruth E. Ley, Michael A. Mahowld, Jeffrey I. Gordon
  • Mycobacterium mutants for vaccines with improved protective efficacy
    Patent number: 8685415
    Abstract: Tuberculosis (TB) is a major health problem and currently, the only licensed TB vaccine is Mycobacterium bovis Bacille Calmette-Guerin (M. bovis BCG). In the present invention, mutation of mycobacterial components reportedly involved in phagosome maturation inhibition was evaluated for vaccine purposes, as such mutations should result in better vaccine antigen processing and presentation. Thus, BCG mutants in genes coding for ManLAM capping ?-1,2-mannosyltransferases and the PI3P phosphatase SapM were evaluated as TB vaccines in a stringent mouse model. Vaccination with both ManLAM capping mutants and the SapM mutant resulted in significantly longer survival as compared to non-vaccinated mice, whereas vaccination with the parental BCG did not. Moreover, mice vaccinated with the SapM mutant survived significantly longer than mice vaccinated with the parental BCG.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: April 1, 2014
    Assignees: VIB VZM, Universiteit Gent, Wetenschappelijk Instituut Volksgezondheid
    Inventors: Nico Callewaert, Anjana Batni, Nele Festjens, Christiane Huygen
  • BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITIS
    Publication number: 20140086877
    Abstract: This document discusses, among other things, receiving a plurality of donor fecal samples from a plurality of donors and storing and indexing each respective donor fecal samples using at least one characteristic of the respective donor fecal sample. In an example, the donor fecal sample can be screened and processed for subsequent use in fecal bacteriotherapy to displace pathogenic or undesired organisms in the digestive track of a patient with healthy or desirable gut micriobiota.
    Type: Application
    Filed: December 2, 2013
    Publication date: March 27, 2014
    Applicant: MikrobEX Inc.
    Inventor: Edwin J. HLAVKA
  • BIOCONTROL COMPOSITIONS
    Publication number: 20140086876
    Abstract: The invention provides isolated Brevibacillius laterosporus strains with insecticidal activity against at least one Lepidoptera species and at least one Diptera species. In particular the invention provides the isolated B. laterosporus strains NMI No. V12/001946, NMI No. V12/001945 and NMI No. V12/001944. The invention provides compositions comprising one or more strain of the invention. The invention also provides methods of use of one or more strains or compositions of the inventions to control pests, particularly insect pests.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 27, 2014
    Inventors: Travis Robert GLARE, John Graham Hampton, Murray Paul Cox, Damian Alexander Bienkowski
  • Use of live bacteria for growth promotion in animals
    Patent number: 8679823
    Abstract: The present invention relates to the use of F4+ non-pathogenic Escherichia coli strains to promote growth in an animal. The present invention also relates to the use of such strains to homogenize growth among a herd of animals. More specifically, the animal(s) of interest in the present invention are those wherein growth promotion or growth homogenization are desired goals, such as animals reared for meat production. The present invention further relates to a method for promoting growth of an animal as well as a method for homogenizing growth among a herd of animals.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: March 25, 2014
    Assignee: Valorisation-Recherche, Limited Partnership
    Inventors: Eric Nadeau, John Morris Fairbrother
  • Non-pathogenic and/or attenuated bacteria capable of inducing apoptosis in macrophages, process of manufacturing and uses thereof
    Patent number: 8679473
    Abstract: The invention relates to an non-pathogenic and/or attenuated bacterium which is capable of inducing apoptosis in macrophages.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: March 25, 2014
    Assignee: Aeterna Zentaris GmbH
    Inventors: Joachim Fensterle, Katharina Galmbacher, Ulf Rapp, Werner Goebel, Christian Hotz
  • COMPOSITION COMPRISING PROBIOTIC BACTERIA CAPABLE OF RESTORING THE BARRIER EFFECT OF THE STOMACH WHICH IS LOST DURING PHARMACOLOGICAL TREATMENT OF GASTRIC HYPERACIDITY
    Publication number: 20140072543
    Abstract: A composition comprising probiotic bacteria for use in the pharmacological treatment of gastric hyperacidity is described. The composition is capable of restoring the barrier effect of the stomach which is lost during pharmacological treatment of gastric hyperacidity and minimizes the secondary effects due to said pharmacological treatment.
    Type: Application
    Filed: April 18, 2012
    Publication date: March 13, 2014
    Inventor: Giovanni Mogna
  • NOVEL THERAPY FOR MULTIPLE SCLEROSIS USING VITAMIN D AND GUT BACTERIA
    Publication number: 20140072534
    Abstract: A method for treating multiple sclerosis in a subject in need of such treatment is provided. The method includes administering a) polysaccharide A and b) vitamin D or a vitamin D metabolite to the subject in an amount effective to treat multiple sclerosis. Also provided is a method for increasing TREG cells in a subject. The method includes administering a) polysaccharide A and b) vitamin D or a vitamin D metabolite to the subject in an amount effective to increase the number of TREG cells in the central nervous system of the subject.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 13, 2014
    Applicant: California Institute of Technology
    Inventors: Sarkis K. Mazmanian, Yunkyung Lee
  • METHOD OF INHIBITING METHANOGENESIS
    Publication number: 20140072535
    Abstract: The object of the present invention is to provide a technique to inhibit methanogens from producing methane. The use of Alcaligenes faecalis can inhibit methanogens from producing methane.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 13, 2014
    Applicants: ABLE CORPORATION
    Inventors: Isami HATANO, Makoto SHODA, Yoichi ISHIKAWA
  • METHOD OF MAKING COSMETIC COMPOSITIONS CONTAINING A PREBIOTIC
    Publication number: 20140072533
    Abstract: A method for indentifying test agents that exhibit prebiotic activity on human skin commensal microorganisms and cosmetic compositions that include such agents. The method includes providing a test culture of a test agent, a human skin commensal microorganism and a minimal carbon medium. The method provides a time efficient and cost effective way to predict in vivo prebiotic activity of a test agent on skin commensal microorganisms.
    Type: Application
    Filed: November 8, 2012
    Publication date: March 13, 2014
    Applicant: THE PROCTER & GAMBLE COMPANY
    Inventor: The Procter & Gamble Company
  • ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM
    Publication number: 20140073501
    Abstract: A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controlling pests using said natural products.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 13, 2014
    Inventors: Ratnakar Asolkar, Marja Koivunen, Pamela Marrone
  • Microorganisms as carriers of nucleotide sequences coding for antigens and protein toxins, process of manufacturing and uses thereof
    Patent number: 8669091
    Abstract: A Escherichia, Salmonella, Yersinia, Vibrio, Listeria, Shigella, or Pseudomonas bacterium that has the following components: (I) a polynucleotide encoding a heterologous antigenic determinant that induces a CTL response against a tumor cell; (II) a polynucleotide encoding a heterologous protein toxin or toxin subunit; and (III) (a) a polynucleotide encoding a transport system that expresses the products of (I) and (II) on the outer surface of the bacterium or that secretes products of (I) and (II) from the bacterium; and (IV) a polynucleotide that activates the expression of one or more of (I). (II), and/Or (III) in the bacterium wherein polynucleotides (I), (II), (III) and (IV) are different from each other and polynucleotides (I), (II) and (III) encode proteins that are different from each other.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: March 11, 2014
    Assignee: Zentaris GmbH
    Inventors: Ivaylo Nikolov Gentschev, Joachim Fensterle, Ulf R. Rapp, Werner Goebel
  • DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDER
    Publication number: 20140065132
    Abstract: Disclosed herein are compositions, systems, and methods for diagnosing and treatment of subjects suffering from anxiety, autism spectrum disorder (ASD), or a pathological condition with one or more of the symptoms of ASD.
    Type: Application
    Filed: August 28, 2013
    Publication date: March 6, 2014
    Inventors: Elaine Hsiao, Sarkis K. Mazmanian, Paul H. Patterson, Sara McBride
  • PROBIOTIC BACTERIA FOR THE TOPICAL TREATMENT OF SKIN DISORDERS
    Publication number: 20140065209
    Abstract: The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use in the treatment of a disorder associated with Tight Junction function, characterised in that the probiotic bacteria, soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria is formulated for topical administration.
    Type: Application
    Filed: May 2, 2012
    Publication date: March 6, 2014
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Heli Putaala, Arthur Ouwehand, Kirsti Tiihonen, Nina Rautonen
  • Method for Removing a Microorganism Biofilm
    Publication number: 20140065122
    Abstract: The invention relates to a method for eliminating a biofilm of microorganism preexisting on an inert surface, characterized in that one subjects said biofilm to a cocktail of microorganisms comprising at least strains said to be “swimming” able to cross said biofilm in the plane and in the thickness, and one subjects said biofilm to at least one antimicrobial product directed against at least one microorganism of the biofilm to be eliminated.
    Type: Application
    Filed: December 16, 2011
    Publication date: March 6, 2014
    Inventors: Romain Briandet, Alexandra Gruss, Stéphane Aymerich, Michel Gohar, Julien Deschamps, Ali Houry
  • PROBIOTIC BACTERIA HAVING ANTIOXIDANT ACTIVITY AND USE THEREOF
    Publication number: 20140065116
    Abstract: The present invention relates to a composition having antioxidant activity. Furthermore, the present invention relates to probiotic bacteria having antioxidant activity and the use thereof.
    Type: Application
    Filed: March 17, 2011
    Publication date: March 6, 2014
    Inventors: Giovanni Mogna, Gian Paolo Strozzi, Luca Mogna
  • PROTEIN STABILIZED PROBIOTICS AND PERSONAL CARE PRODUCTS
    Publication number: 20140065210
    Abstract: The present invention relates to a personal care product comprising a protein matrix wherein said protein matrix comprises at least one protein, at least one probiotic and a carrier fluid. The present invention also relates to the personal care product being a feminine care product particularly aimed at female urogenital health to treat or prevent vaginal infections. Oral and sinus infections, however, may also be benefited by the composition.
    Type: Application
    Filed: August 29, 2012
    Publication date: March 6, 2014
    Inventors: David W. Koenig, Neil T. Scholl, Vasily A. Topolkaraev, Amy L. Vanden Heuvel
  • NOVEL LACTIC ACID BACTERIA AND COMPOSITIONS CONTAINING THEM AGAINST BACTERIAL COLDS
    Publication number: 20140065218
    Abstract: The invention describes a microorganism of the order of lactic acid bacteria or an analogue, fragment, derivative, mutant or combination thereof, wherein the microorganism, or analogue, fragment, derivative, mutant or combination thereof can coaggregate with Streptococcus pyogenes.
    Type: Application
    Filed: May 16, 2012
    Publication date: March 6, 2014
    Applicant: ORGANOBALANCE MEDICAL AG
    Inventors: Christine Lang, Andreas Raab, Natalia Bolotina
  • APPARATUS, SYSTEM, AND METHOD FOR CREATING BIOLOGICALLY PROTECTED/ENHANCED SPACES IN VIVO
    Publication number: 20140056958
    Abstract: The present invention creates a biologically protected or enhanced space in vivo in a mammal to allow the mammal's immune system and/or other biological processes to function properly in order to treat autoimmune diseases. In particular, the biologically protected/enhanced space allows biological processes to occur that can therapeutically treat Type I diabetes. The biologically enhanced/protected space can also be used to promote growth of specific cells such as insulin producing islet cells of the pancreas. Microfluidic devices can also be used to remove soluble TNF receptors and autoreactive T Cells in treating autoimmune diseases. Additionally, microfluidic devices can be used to remove blood glucose, soluble insulin receptors and insulin-like growth factor (IGF) from blood in the treatment of adult onset (Type II) diabetes.
    Type: Application
    Filed: March 5, 2012
    Publication date: February 27, 2014
    Inventors: Charles Knezevich, Robert D. Silvetz
  • NUTRITIONAL COMPOSITIONS HAVING ALPHA-HICA AND ALPHA-KETOGLUTARATE
    Publication number: 20140056862
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and ?-ketoglutarate. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, citrulline, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 27, 2014
    Applicant: Nestec S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • NUTRITIONAL COMPOSITIONS HAVING ALPHA-HICA AND EICOSAPENTAENOIC ACID
    Publication number: 20140056863
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid eicosapentaenoic acid. It may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, citrulline, ?-ketoglutarate, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 27, 2014
    Applicant: Nestec S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • COATING COMPOSITIONS FOR PATHOGEN CONTROL IN MONOCOTYLEDONOUS PLANTS
    Publication number: 20140056956
    Abstract: Coating composition for applying to a plant structure of a monocotyledonous plant from which roots and shoots are capable of growing, wherein the said coating composition comprises an organic carrier material and one or more biological agents that possess an activity against at least one or more pathogens of the said monocotyledonous plant.
    Type: Application
    Filed: April 19, 2012
    Publication date: February 27, 2014
    Applicant: EXOSECT LIMITED
    Inventor: Nicholas Hugh Hylton Jessop
  • MATERIALS AND METHODS FOR CONTROLLING NEMATODES WITH PASTEURIA SPORES IN SEED COATINGS
    Publication number: 20140057784
    Abstract: The subject invention provides novel and advantageous materials and methods for controlling phytopathogenic and/or soil-dwelling nematodes by attaching an effective amount of Pasteuria spores to a seed and delivering the seeds to the situs of nematodes.
    Type: Application
    Filed: October 31, 2013
    Publication date: February 27, 2014
    Applicant: PASTEURIA BIOSCIENCE, INC.
    Inventors: THOMAS E. HEWLETT, JOHN P. WATERS, CHARLES S. BARMORE
  • BIFIDOBACTERIUM BIFIDUM STRAINS FOR APPLICATION IN GASTROINTESTINAL DISEASES
    Publication number: 20140056852
    Abstract: The present invention provides a strain of Bifidobacterium bifidum or mutant or variant thereof showing at least an adhesion of about 10 bacterial cells per mm2 of epithelial cell monolayer or having at least an adhesion index of 1.5 and a strain of Bifidobacterium bifidum or mutant or variant thereof being Bifidobacterium bifidum MIMBb75, deposited under deposit No. DSM 24514, or a mutant or variant thereof for use as probiotic, in foodstuff and/or as a medicament. Further provided is a probiotic for mulation, comprising any of the strains, mutants or variants mentioned above, uses of said probiotic formulation, strains, mutants and variants thereof and a method for producing said probiotic formulation.
    Type: Application
    Filed: January 27, 2012
    Publication date: February 27, 2014
    Applicant: NATURWOHL PHARMA GMBH
    Inventors: Simone Guglielmetti, Diego Mora
  • COATING COMPOSITIONS FOR PATHOGEN CONTROL IN COTTON
    Publication number: 20140057786
    Abstract: Coating compositions for cotton plant seed, wherein the coating composition comprises an organic carrier material and one or more biological agents that are active against one or more pathogens cotton plant.
    Type: Application
    Filed: April 19, 2012
    Publication date: February 27, 2014
    Applicant: EXOSECT LIMITED
    Inventor: Nicholas Hugh Hylton Jessop
  • Compositions and Methods for Modulating Plant Parasitic Nematodes
    Publication number: 20140056853
    Abstract: Provided is a method for modulating soybean cyst nematode infestation of a plant comprising applying to the plant an effective amount of a composition comprising a Chromobacterium, Burkholderia, and/or Flavobacterium strain to modulate the soybean cyst nematode infestation. The composition may be applied directly to the seed or in a substrate for growing the plant, such as in the soil.
    Type: Application
    Filed: November 5, 2013
    Publication date: February 27, 2014
    Applicant: Marrone Bio Innovations, Inc.
    Inventors: Pamela Marrone, Timothy B. Johnson, Hai Su, Lijuan Xing, Phyllis Himmel
  • Altering the interface of hydrocarbon-coated surfaces
    Patent number: 8658412
    Abstract: Methods and compositions are provided wherein microorganisms are used to alter the interface of hydrocarbons and hydrocarbon-coated surfaces to increase oil recovery, for improved bioremediation and/or pipeline maintenance.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: February 25, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Eric R. Choban, Robert D. Fallon, Edwin R. Hendrickson, Scott Christopoher Jackson, Abigail K. Luckring, Michael P. Perry, David Alan Suchanec, Sheryl M. Anzek
  • SCAVENGER RECEPTOR UPTAKE FOR FABRY DISEASE ENZYME REPLACEMENT THERAPY
    Publication number: 20140050666
    Abstract: The present invention relates to a composition comprising a lysosomal enzyme conjugated to a negatively charged scavenger receptor ligand. In some embodiments, the lysosomal enzyme is conjugated to the scavenger receptor ligand by way of a linker. The present invention also relates to a composition comprising lysosomal enzyme encapsulated by a liposome, said liposome externally comprising a negatively charged scavenger receptor ligand. The invention further encompasses a method of treating a lysosomal storage disease with the compositions listed above. The invention further encompasses a method of treating a lysosomal storage disease with an acylated, acetylated, or aconitylated lysosomal enzyme.
    Type: Application
    Filed: August 19, 2013
    Publication date: February 20, 2014
    Applicant: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: David H. Calhoun, Lane Gilchrist
  • SEED TREATMENT METHOD AND COMPOSITION
    Publication number: 20140051573
    Abstract: A method of treating seeds, comprising: providing a batch of seeds; adding a first mixture comprising at least one insecticide, at least one fungicide, and at least one coating agent to the seeds over a period of about 6 to 15 seconds; homogenizing the seeds for 5 to 25 seconds; adding a second mixture comprising at least one inoculant and at least one protectant to seeds over a period of about 6 to 15 seconds; and homogenizing the seeds for about 5 to 25 seconds.
    Type: Application
    Filed: May 7, 2012
    Publication date: February 20, 2014
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventor: Carlos Becco
  • EQUOL-PRODUCING LACTIC ACID BACTERIA-CONTAINING COMPOSITION
    Publication number: 20140050703
    Abstract: An equol-producing lactic acid bacteria-containing composition comprises, as an essential component thereof, a lactic acid bacterial strain belonging to the genus Lactococcus having an ability to utilize at least one daidzein compound selected from the group consisting of daidzein glycosides, daidzein, and dihydrodaidzein to produce equol. Such a composition is effective for the prevention and alleviation of malaise inclusive of climacteric disturbance in middle-aged and elderly women for which no effective prophylactic method or alleviating means has heretofore been available.
    Type: Application
    Filed: September 24, 2013
    Publication date: February 20, 2014
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Shigeto UCHIYAMA, Tomomi UENO, Toshimi SUZUKI
  • Pasteuria strain
    Patent number: 8652490
    Abstract: The subject invention provides a novel and advantageous strain of Pasteuria bacteria with nematicidal activity against Reniform nematodes. The subject invention provides the novel bacteria culture referred to as ATCC PTA-9643, and mutants thereof. Also provided are nematicidal compositions comprising the Pasteuria strain or its mutants or variants and methods for treating phytopathogenic and soil-dwelling nematodes.
    Type: Grant
    Filed: January 26, 2010
    Date of Patent: February 18, 2014
    Assignee: Pasteuria Bioscience, Inc.
    Inventors: Thomas E. Hewlett, John P. Waters
  • COATING COMPOSITIONS FOR PATHOGEN CONTROL IN VEGETABLES
    Publication number: 20140045688
    Abstract: Coating composition for applying to a vegetable plant structure such as a seed of a vegetable plant from which roots and shoots are capable of growing, wherein the said coating composition comprises an organic carrier material in particulate form and one or more biological agents that possess an activity against at least one or more pathogens of the said vegetable plant
    Type: Application
    Filed: April 19, 2012
    Publication date: February 13, 2014
    Applicant: EXOSECT LIMITED
    Inventor: Nicholas Hugh Hylton Jessop
  • NUTRITIONAL COMPOSITIONS HAVING ALPHA-HICA AND CITRULLINE
    Publication number: 20140044685
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and citrulline. The composition may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, ?-keto-glutarate, eicosapentaenoic acid, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 13, 2014
    Applicant: NESTEC S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • NUTRITIONAL COMPOSITIONS INCLUDING BRANCHED CHAIN FATTY ACIDS AND METHODS OF USING SAME
    Publication number: 20140037602
    Abstract: Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include allergies, autoimmune diseases, among others. The nutritional compositions include branched chain fatty acids and may include other functional ingredients such as, but not limited to probiotics, nucleotides and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 6, 2014
    Applicant: NESTEC S.A.
    Inventors: Doug Bolster, Norman Alan Greenberg, Jennifer Mager, Zamzam Kabiry (Fariba) Roughead
  • MICROENCAPSULATED BIOACTIVE AGENTS FOR ORAL DELIVERY AND METHODS OF USE THEREOF
    Publication number: 20140037743
    Abstract: The presently claimed and disclosed inventive concept(s) contemplates a novel polymeric oral dosage form (transmucosal delivery vehicle) for delivery of pharmaceutical and nutriceutical bioactive agents to the mucosa and bloodstream of the intestine. The oral dosage form of the presently claimed and disclosed inventive concept(s) comprises a polymeric coating which encapsulates the bioactive agent and inhibits degradation and dissolution of the bioactive agent within the stomach and within the lumen of the intestine until after passing through the mucosal wall of the small and/or large intestine. The enzymatic degradation of the polymeric delivery vehicle containing the bioactive agent is substantially inhibited until after absorption of the polymeric delivery vehicle into blood vessels of the intestinal mucosa.
    Type: Application
    Filed: October 11, 2013
    Publication date: February 6, 2014
    Applicant: DelivRx, Inc.
    Inventor: Daniel R. DeBrouse
  • ANTICOCCIDIAL COMPOSITION
    Publication number: 20140037605
    Abstract: [Objects] An object of the present invention is to provide an orally administrable agent for medical use for animals for preventing or treating coccidiosis which is highly safe with no side effects, an agent for a food or a drink for use in the preservation of health, a feed additive, and a feed comprising the same. Another object of the present invention is to provide a method for rearing animals (particularly, livestock and poultry) using the same and a method for controlling coccidiosis using the same. [Means for Resolution] By using a fermentation product of a lactic acid bacterium and/or a whey fermentation product of a propionic acid bacterium as an active ingredient, an agent for preventing or treating coccidiosis, an agent for use in the preservation of health, and a feed additive can be provided.
    Type: Application
    Filed: October 10, 2013
    Publication date: February 6, 2014
    Applicants: MEIJI CO., LTD., MEIJI FEED CO., LTD.
    Inventors: Kenji SERA, Takanori MASHIKO, Shuji IKEGAMI, Takenori ORIHASHI, Michio KANBE
  • BACTERIUM-BASED MICROROBOT CAPABLE OF TARGETING CANCER TISSUE
    Publication number: 20140037553
    Abstract: To provide a bacterium-based microrobot which can be specifically targeted to cancer in vivo, the present invention provides a drug delivery system for cancer tissue, comprising a bacterium, and a microbead encapsulated with at least one drug, wherein biotin is bound to a surface of the bacterium and a surface of the microbead is coated with streptavidin.
    Type: Application
    Filed: July 29, 2013
    Publication date: February 6, 2014
    Applicant: Industry Foundation of Chonnam National University
    Inventors: Suk Ho Park, Jong Oh Park, Sung Jun Park, Seong Young Ko, Jung Joon Min, Seung Hwan Park
  • NUTRITIONAL COMPOSITIONS COMPRISING ALPHA-HYDROXYISOCAPROIC ACID
    Publication number: 20140037604
    Abstract: Nutritional compositions for maximizing muscle protein synthesis while minimizing the catabolism of muscle proteins and methods of using same are provided. In this manner, the nutritional compositions may provide for retention of lean body mass, which helps to avoid loss of independence and functionality, as well as to improve quality of life especially in the elderly at risk of sarcopenia and frailty. The nutritional compositions include ?-hydroxyisocaproic acid and may include other functional ingredients such as, but not limited to whey protein including whey protein micelles, prebiotic fibers, L-carnitine, nucleotides, and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 18, 2012
    Publication date: February 6, 2014
    Applicant: NESTEC S.A.
    Inventors: Norman Alan Greenberg, Denis Breuille, Zamzam Kabiry (Fariba) Roughead, Doug Bolster, Jennifer Mager
  • NUTRITIONAL COMPOSITIONS INCLUDING BRANCHED CHAIN FATTY ACIDS FOR WOUND HEALING
    Publication number: 20140037601
    Abstract: Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include wounds, mucositis among others. The nutritional compositions include branched chain fatty acids and may include other functional ingredients such as, but not limited to probiotics, nucleotides and amino acids. Methods of administering such nutritional products to individuals in need of same are also provided.
    Type: Application
    Filed: April 12, 2012
    Publication date: February 6, 2014
    Applicant: NESTEC S.A.
    Inventor: Norman Alan Greenberg
  • Tuberculosis vaccine
    Patent number: 8642011
    Abstract: The present invention relates to an isolated microorganism belonging to the genus Mycobacterium, characterized in that it comprises inactivating the gene Rv0757 that confers a PhoP? phenotype and inactivating a second gene that prevents the production of DIM (DIM-phenotype). Additionally, the present invention comprises the use of said microorganism for producing a vaccine for immunizing against or preventing tuberculosis.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: February 4, 2014
    Assignee: Universidad de Zaragoza
    Inventors: Carlos Martin Montanes, Brigitte Gicquel, Esther Perez Herran, Jesus Gonzalo Asensio, Ainhoa Arbues Arribas
  • Methods and Compositions of Biocontrol of Plant Pathogens
    Publication number: 20140030228
    Abstract: The present invention comprises methods and composition for control of plant pathogens. Isolated bacteria, deposited with ATCC under the Budapest Treaty, are effective to control plant pathogens.
    Type: Application
    Filed: July 30, 2013
    Publication date: January 30, 2014
    Inventors: Luke D. Blotsky, Derex Q. Zellars, Michael L. Lindsey
  • Compositions and Methods for the Treatment of Hepatic Diseases and Disorders
    Publication number: 20140030194
    Abstract: The disclosure provides oral compositions and methods of using such compositions in treating subjects infected with one or more hepatic disorders. The compositions include lysates or cell wall extracts of one or more gram positive bacteria, exhibit particular activity against hepatitis C virus (HCV), and may be useful in treating those infected with HCV as well as other hepatic diseases or disorders. Also described are methods of treating a hepatic disease or disorder by administering a therapeutically effective amount of at least one therapeutically active agent capable of upregulating or downregulating the Complement system pathway, wherein the therapeutically active agent enhances the formation of one or more convertase enzymes.
    Type: Application
    Filed: January 16, 2013
    Publication date: January 30, 2014
    Applicant: Labyrinth Bio, Inc.
    Inventor: Elizabeth McKenna
  • COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OXALATE-RELATED DISEASE
    Publication number: 20140030324
    Abstract: The present invention comprises methods and compositions for the reduction of oxalate in humans, animals and plants. For example, the invention provides methods and compositions for the delivery of one ore more oxalate-reducing enzymes to the intestinal tracts of persons and animals. The methods and compositions can be used in treating and preventing oxalate-related conditions.
    Type: Application
    Filed: June 17, 2013
    Publication date: January 30, 2014
    Applicants: The Milton J. Allison Revocable Trust, OxThera, Inc.
    Inventors: Harmeet Sidhu, Milton J. Allison
  • NUTRITIONAL COMPOSITIONS FOR INCREASING ARGININE LEVELS AND METHODS OF USING SAME
    Publication number: 20140030241
    Abstract: Nutritional compositions having dietary nucleotides, ?-3 fatty acids and citrulline are provided. The nutritional compositions may be formulated to improve T cell function, increase arginine availability in vivo, regulate myeloid-derived suppressor cells (“MDSC”), and decrease the risk and/or severity of infection after surgery or trauma. Methods of making, using and administering such nutritional compositions to individuals in need of same are also provided. Methods for modulating the affects of MDSC's are also provided.
    Type: Application
    Filed: March 15, 2012
    Publication date: January 30, 2014
    Applicant: NESTEC S.A.
    Inventor: Norman Alan Greenberg
  • Isolation, identification and characterization of strains with probiotic activity, from faeces of infants fed exclusively with breast milk
    Patent number: 8637297
    Abstract: The invention relates to probiotic micro-organisms isolated from faeces of children exclusively fed with breast milk. Said microorganisms are used in the food or pharmaceutical industry, especially for use in infant formula milk, due to their probiotic properties which have beneficial effects on the health of those ingesting them. Said microorganisms consist of Lactobacillus rhamnosus HERO 22A (CNCM I-4036), Lactobacillus paracasei HERO 7 (CNCM I-4034) and Bifidobacterium breve HERO 15B (CNCM I-4035).
    Type: Grant
    Filed: March 9, 2010
    Date of Patent: January 28, 2014
    Assignee: Hero AG
    Inventors: Jose Maria Vieites Fernandez, Sergio Munoz Quezada, Inmaculada Llamas Company, Jose Maldonado Lozano, Fernando Romero Braquehais, Antonio Francisco Suarez Garcia, Angel Gil Hernandez, Carolina Gomez Llorente, Miriam Bermudez Brito