Flexible Web, Sheet, Film, Or Filament Base (e.g., Fabric, Bandage, Suture, Transdermal Patch, Orthopedic Cast Tape) Patents (Class 427/2.31)
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Publication number: 20090064897Abstract: Tint bases include dual functional polymers and pigments. Methods of preparing tint bases include obtaining a dual functional polymer, obtaining a pigment, and combining the dual functional polymer and the pigment. Coating compositions, kits, and methods of coating employing the tint bases are also provided.Type: ApplicationFiled: September 12, 2007Publication date: March 12, 2009Applicant: Guertin, Coatings, Sealants and Polymers, Ltd.Inventors: Sean Philippe GUERTIN, Charles Guertin, Ron Chemerika, Thi Nguyen
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Publication number: 20090061073Abstract: The present invention refers to a cast coating device for manufacturing cast coated paper and/or paperboard, comprising a cast coating cylinder for treating a coated base paper, the cast coating cylinder comprising a supporting material and at least one coating applied to the supporting material, characterized in that according to DIN 50133 the coating has a hardness value of 1000 HV or more, as well as to a process of manufacturing a cast coated paper.Type: ApplicationFiled: June 21, 2006Publication date: March 5, 2009Inventors: Hans-Joachim Becher, Andreas Euler, Thomas Grosser, Willi Hammerschmidt
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Publication number: 20090062711Abstract: Hydrophilic compositions are described, which are prepared from a first oligomer containing pendent polymerizable groups and pendent hydrophilic groups, crosslinked with a co-reactive second component oligomer possessing photoinitiator groups. The compositions may be used as in preparation of hydrophilic gel coatings or layers for medical devices.Type: ApplicationFiled: November 4, 2008Publication date: March 5, 2009Inventors: Kevin M. LEWANDOWSKI, Duane D. Fansler, Michael S. Wendland, Steven M. Heilmann, Babu N. Gaddam
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Publication number: 20090062712Abstract: A material for producing a support bandage, which comprises a support. Said support is coated and/or impregnated with a curable plastic material and at least partially configured by a leno fabric comprising warp yarns that cross between two weft yarns running in parallel. Said leno fabric comprises at least one additional warp yarn that is located between two pairs of crossing warp yarns and does not cross any other warp yarn.Type: ApplicationFiled: December 13, 2004Publication date: March 5, 2009Applicant: LOHMANN & RAUSCHER GMBH & CO. KGInventor: Helmut Leuprecht
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Publication number: 20090048652Abstract: A medical device having at least one plasma polymerized coating allowing for a first component to be coupled with a second component.Type: ApplicationFiled: August 13, 2007Publication date: February 19, 2009Applicant: Cardiac Pacemakers, IncInventors: Shamim M. Malik, Paul E. Zarembo, Larry L. Hum
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Publication number: 20090048627Abstract: The present disclosure provides a method for forming a color pattern on a medical device.Type: ApplicationFiled: February 22, 2007Publication date: February 19, 2009Inventor: Ahmad R. Hadba
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Patent number: 7485111Abstract: Embodiments of the invention provide a stretchable sleeve having a medicinal section that can be loaded with a medicinal composition and a perforated section comprising a plurality of openings, wherein the medicinal section and the perforated section overlap, and wherein the sleeve is sized so that the interior surface of the medicinal section comfortably fits a body portion and the medicinal section contacts the body portion at the site of pain. Embodiments of the invention also provide methods for preparing a sleeve by applying a medicinal composition to the inner surface of the medicinal section through the openings at the perforated section. Embodiments of the invention also provide methods for relieving pain in a body portion by pulling the sleeve in an outside-out configuration straight up a body portion without having to roll and flip its exterior surface outside.Type: GrantFiled: September 22, 2006Date of Patent: February 3, 2009Inventors: Eugene Choi, Dong Hwan Choi, Mun Seok Han
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Publication number: 20090024067Abstract: A multi-layered wound dressing includes a moisture-retaining portion for enhancing the healing of a wound. The wound dressing includes an intermediate layer that has both water soluble and water insoluble fibers. An apparatus that includes a cutting tool and a reservoir of liquid to pre-moisten a portion of the dressing may be used to manufacture the dressings.Type: ApplicationFiled: August 26, 2008Publication date: January 22, 2009Applicant: POLYREMEDY INC.Inventor: Oleg Siniaguine
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Publication number: 20090011117Abstract: A method for fabricating an endovascular implant includes providing a mold having a controlled topography. A wire is positioned about at least a portion of the mold. A polymeric material coating is applied to cover at least a portion of the mold. The wire and the polymeric material coating are released from the mold, wherein the polymeric material coating has a controlled topography at least partially replicating the controlled topography of the mold.Type: ApplicationFiled: July 2, 2008Publication date: January 8, 2009Applicant: ENDOTRONIX, INC.Inventors: Anthony I. Nunez, Harry D. Rowland
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Publication number: 20090004126Abstract: A method for coating a skin blemish (10) such that the coated blemish visually blends into the surrounding skin (12) comprises measuring at least one colour property of the skin blemish (10) and measuring at least one colour property of the surrounding skin (12), suitably by using a spectrophotometer. From the measured properties, a coating composition having a compensatory colour is determined. When the skin blemish (10) is coated with the coating composition, the blemish (10) blends into the surrounding skin (12). The coating composition is not of identical colour to the surrounding skin (12) and the coating composition has a degree of translucency. The coated skin has a very natural look.Type: ApplicationFiled: July 29, 2005Publication date: January 1, 2009Inventor: Linda Jane Lowndes
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Publication number: 20080314422Abstract: A system and method of forming and using a proximity head. The proximity head includes a head surface, the head surface including a first zone, a second zone and an inner return zone. The first zone including a first flat surface region and a plurality of first discrete holes. Each one of the plurality of first discrete holes being connected to a corresponding one of a plurality of first conduits. The plurality of first discrete holes residing in the head surface and extending through the first flat surface region. At least a portion of the plurality of first discrete holes are arranged in a first row. The second zone including a second flat region and a plurality of second discrete holes. Each one of the plurality of second discrete holes being connected to a corresponding one of a plurality of second conduits. The plurality of second discrete holes residing in the head surface and extending through the second flat surface region. The inner return zone including a plurality of inner return discrete holes.Type: ApplicationFiled: June 19, 2007Publication date: December 25, 2008Applicant: Lam Research CorporationInventors: Robert O'Donnell, Cheng-Yu (Sean) Lin, Arnold Kholodenko
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Publication number: 20080319371Abstract: A method to electrokinetically deliver a medicament to a nail of a mammalian user including: forming a cast of the nail of the user wherein the cast is a reverse impression of the nail; applying a medicament matrix to the nail; sandwiching the medicament matrix between the cast and the nail; pressing the medicament matrix to the nail using the cast; applying electrical current to an electrical current path extending through the medicament matrix and the nail, and delivering medicament from the matrix into the nail by electrokinetic transporting the medicament along the current path.Type: ApplicationFiled: June 19, 2008Publication date: December 25, 2008Applicant: TRANSPORT PHARMACEUTICALS, INC.Inventors: Robert W. Etheredge, Dennis I. Goldberg, Shawn P. Davis, Bireswar Chakraborty, Michael S. Barsness
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Publication number: 20080319368Abstract: Provide is a skin plate product, which can be better tailored with respect to controlling the properties of the first and second surfaces. This is obtained by cutting holes in an adhesive matrix with a laser and subsequently filling these holes with a second material. Being able to design the exact location, orientation, distribution and/or size of the second material opens the path for adhesive products where e.g. adhesion, absorption, and permeability are controlled and balanced.Type: ApplicationFiled: June 30, 2005Publication date: December 25, 2008Inventors: Mads Lykke, Frank Berg Rasmussen, Chaabane Bougherara, Carsten Sletten
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Publication number: 20080312686Abstract: A closure element is disclosed. The closure element includes a body. The body includes a plurality of tissue engaging portions extending from the body. The body is movable from a compressed state to a deployed state. The body includes a material. Silver or alloys thereof are included as a component of a coating over and/or a mixture with the material of at least a portion of the body.Type: ApplicationFiled: June 9, 2008Publication date: December 18, 2008Applicant: ABBOTT LABORATORIESInventor: Brian A. Ellingwood
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Patent number: 7449211Abstract: The present invention provides a bio-sheet material, and a method and an apparatus of manufacturing the bio-sheet, which has pliability or easiness of cutting by unifying a mixture of at least one of healthful natural minerals or plants such as ocher, jade, tourmalin, etc., using fiber material, paper, etc., as a medium, which can be maintained in an original shape at natural or heat drying without generating separation of the mixture, and which can shorten the manufacturing time.Type: GrantFiled: May 24, 2006Date of Patent: November 11, 2008Inventor: Jong-Hak Lee
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Publication number: 20080264336Abstract: The present invention has several plausible embodiments. In one embodiment an apparatus for coating a medical device is provided. This apparatus includes a coating chamber, a vibrating structure within the coating chamber the vibrating structure capable of suspending a medical device positioned in the coating chamber, and a coating source, the coating source positioned to introduce coating into the coating chamber. In another embodiment a method of coating a medical device is provided. This method includes moving a medical device into a predetermined coating area, vibrating a structure below the medical device, the vibration of the structure forcing the medical device away from the vibrating structure, and coating at least a portion of the medical device that has moved away from the vibrating structure.Type: ApplicationFiled: June 25, 2008Publication date: October 30, 2008Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Marlene C. Schwarz, Stanley Tocker
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Publication number: 20080262460Abstract: Absorbent articles comprising high barrier sheets that comprise an ink composition that is applied in aqueous form, typically (substantially) free of organic solvents, and processes for making such articles. The sheets are typically used as or part of a cuff, such as an anal and/or genital cuff (also referred to as topsheet with opening or openings) or leg cuff or barrier cuff, used in for example diapers. The water-based ink comprises typically surfactant and a specific water-based film-forming polymer solution or dispersion.Type: ApplicationFiled: February 13, 2008Publication date: October 23, 2008Applicant: The Procter & Gamble CompanyInventors: Wenbin Li, Alrick Vincent Warner, Ekaterina Anatolyevna Ponomarenko
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Publication number: 20080234618Abstract: The present invention provides a method of making a bandage from a fabric such as a knitted fabric, for example. The fabric is steamed, sprayed with a solution containing an antibacterial/antimicrobial agent in a spraying chamber 28 and then dried in a drying chamber 40.Type: ApplicationFiled: October 6, 2006Publication date: September 25, 2008Applicant: Laboratories Urgo SASInventor: David Timothy Baldock
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Publication number: 20080228109Abstract: A guide wire includes a member with a core wire. The guide wire may have a marker-forming layer which partly encircles the outer surface of the member and differs in color from the member, and a coating layer which covers the marker-forming layer and the member at least in the region where the marker-forming layer is formed and has such transparency as to make the marker-forming layer visible. The marker-forming layer and the coating layer can be formed from mutually miscible resins, while the marker-forming layer functions as a visible marker.Type: ApplicationFiled: March 14, 2008Publication date: September 18, 2008Applicant: TERUMO KABUSHIKI KAISHAInventors: Yasushi Kinoshita, Junichi Kobayashi, Tadashi Kousai
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Patent number: 7425345Abstract: An apparatus comprises a dispenser, a coherent energy source and an beam steering system. The dispenser defines a path of a droplet. The beam steering system is coupled to the coherent energy source and is configured to define a beam path of the coherent energy source. The beam path of the coherent energy source is disposable across the dispenser path at an interaction location. The beam steering system and coherent energy source are collectively configured such that at least one of a direction, a velocity and an acceleration of the droplet is modified within the interaction location.Type: GrantFiled: March 2, 2004Date of Patent: September 16, 2008Assignee: Boston Scientific Scimed, Inc.Inventor: Jan Weber
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Publication number: 20080220149Abstract: The use of NIPAM polymers to prevent or reduce the formation of protein deposits on the surfaces of medical devices is described. The invention is particularly directed to reduction of the adsorption of proteins on surfaces of contact lenses and other medical prosthetics.Type: ApplicationFiled: May 27, 2008Publication date: September 11, 2008Inventor: Howard Allen Ketelson
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Publication number: 20080200331Abstract: The present invention relates to a process for producing a water-absorbing material comprising the steps of a) spray-coating water-absorbing polymeric particles with an elastic film-forming polymer in a fluidized bed reactor in the range from 00 C to 1500 C and b) heat-treatment of the coated particles at a temperature above 50° C., wherein in step b) the duration of the heat-treatment is chosen that the CS-SFC value of the obtained polymeric particles is at least 10% of the optimum CS-SFC value, and the water-absorbing material obtainable by this process.Type: ApplicationFiled: February 3, 2006Publication date: August 21, 2008Inventors: Thomas Daniel, Ulrich Riegel, Stefan Bruhns, Mark Elliott, Karl Haberle, Mattias Schmidt, Axel Meyer, Renae Dianna Fossum, Jean-Philippe Marie Autran
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Publication number: 20080145391Abstract: An article and process provides a stable technology that reduces the microbial content by providing molecular iodine to the stabilized reagents when at least two reactants are activated by aqueous and/or alcohol materials.Type: ApplicationFiled: December 7, 2007Publication date: June 19, 2008Inventors: Anthony R. Nelson, Susan T. Oeltjen, Christopher J. Rueb, William A. Hendrickson, Kenneth R. Code
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Patent number: 7387836Abstract: There are disclosed novel uses of aziridine compounds. The aziridine compounds can be formed into films by plasma deposition on a wide variety of substrates. The films prevent biofouling, impart biocompatible or antithrombotic properties, and can immobilize therapeutic and pharmaceutical agents to provide a drug delivery system.Type: GrantFiled: April 17, 2003Date of Patent: June 17, 2008Assignee: Genzyme CorporationInventors: Diego A. Gianolio, Erika E. Johnston, Robert J. Miller
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Patent number: 7384661Abstract: A method of electrostatically applying a powder material to a solid dosage form comprises the following steps: applying a bias voltage to generate an electric field between a source (1) of the powder material and the solid dosage form (5); applying an electrostatically charged powder material to the solid dosage form (5), the powder material being driven onto the solid dosage form (5) by the interaction of the electric field with the charged powder material, an the presence of the charged powder material on the solid dosage form serving to build up an electric charge on the solid dosage form (5) and thereby reduce the electric field generated by the bias voltage between the source (1) of powder material and the solid dosage form (5), and continuing the application of the electrostatically charged powder material to the solid dosage form (5) until the electric field between the source (1) of powder material and the solid dosage form is so small that the driving of the powder material by the electric field ontoType: GrantFiled: December 21, 2001Date of Patent: June 10, 2008Assignee: Phoqus Pharmaceuticals LimitedInventors: David Hoover Feather, Douglas Howard Nelson
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Patent number: 7335391Abstract: A method of forming a coating for an implantable medical device, such as a stent, is provided which includes applying a composition to the device in an environment having a selected pressure.Type: GrantFiled: December 5, 2003Date of Patent: February 26, 2008Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Stephen D. Pacetti
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Patent number: 7323208Abstract: Modified porous materials are disclosed having interconnected, complexly shaped three-dimensional surfaces. The modification is accomplished by crosslinking the three-dimensional surfaces and/or by coating the three-dimensional surfaces with a layer of a predetermined material. The porous materials are macro structures including at least one of nano-features, micro-features, and combinations thereof. The modifying accomplishes changing surface properties of the porous materials, changing the three-dimensional surfaces, and/or rendering the porous materials substantially stable in a predetermined environment.Type: GrantFiled: November 30, 2004Date of Patent: January 29, 2008Assignee: The Regents of the University of MichiganInventors: Peter X. Ma, Xiaohua Liu
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Publication number: 20070286942Abstract: A biomedical material is prepared through a plasma method. The material is a film containing titanium oxide onto polymer sheet. The film is hydrophilic, bacterial inactivated and biocompatible. The present invention can be applied to artificial guiding tube and wound dressing material.Type: ApplicationFiled: October 26, 2006Publication date: December 13, 2007Applicant: ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR ENERGY RESEARCHInventors: Te-Hsing Wu, Ko-Shao Chen, Chia-Chieh Chen, Lie-Hang Shen, Yi-Chun Yeh, Nini-Chen Tsai
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Patent number: 7294357Abstract: Suture filaments coated by a plasma polymerization process exhibit a good balance of knot run down and knot security characteristics, superior tissue drag characteristics, and improved fray resistance.Type: GrantFiled: September 28, 2001Date of Patent: November 13, 2007Assignee: Tyco Healthcare Group LPInventor: Mark Roby
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Patent number: 7235278Abstract: A method and apparatus of applying a particulate material to a substrate includes applying adhesive to the substrate and passing the substrate through a chamber in which a particulate material is suspended in a fluid in order to adhere the particulate material to the substrate.Type: GrantFiled: February 10, 2005Date of Patent: June 26, 2007Assignee: McNeil-PPC, Inc.Inventors: Paul Y. Fung, Denis Tremblay
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Patent number: 7198855Abstract: The present invention provides methods of producing a surface with enhanced cell-adhesive properties comprising applying a stress to a polymeric matrix. The strained matrix is then modified by grafting a self-assembled monolayer onto the strained matrix, with the self-assembled monolayer comprising at least one exposed functional group. At least one cell-adhesive molecule can then be coupled to the at least one exposed functional group on the self-assembled monolayer to produce a surface with enhanced cell-adhesive properties.Type: GrantFiled: September 12, 2003Date of Patent: April 3, 2007Assignees: Becton, Dickinson and Company, North Carolina State UniversityInventors: Andrea Liebmann-Vinson, Bryce Chaney, Kirill Efimenko, Jan Genzer
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Patent number: 7172785Abstract: The invention relates to a process for depositing a metal on a material. The process comprises the steps of: immersing the material in deposition solution comprising the metal; inducing a material vibration in the deposition solution having a frequency corresponding to a resonance frequency of the material; including a solution vibration in the deposition solution in a direction non-parallel to the material vibration, said solution vibration having a frequency corresponding to the a resonance frequency of the deposition solution, whereby said metal is deposited onto the material. This process results in deposition of metal from the plating bath on the material in a controlled and substantially uniform thickness.Type: GrantFiled: July 11, 2001Date of Patent: February 6, 2007Inventors: G. Alan Thompson, Theresa M Anderson, David E. Marx
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Patent number: 7144976Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.Type: GrantFiled: May 8, 2002Date of Patent: December 5, 2006Assignee: Ethicon, Inc.Inventors: Takehisa Matsuda, Manabu Mizutani, Steven Arnold
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Patent number: 7132122Abstract: This invention provides novel methods for creation of patterned lipid bilayer membranes as well as methods for refunctionalization of such patterned membranes with selected components. Such components optionally comprise, e.g., lipid bilayer membranes (which optionally comprise specific proteins), proteins, non-biologic moieties, etc.Type: GrantFiled: October 30, 2003Date of Patent: November 7, 2006Assignee: The Regents of the University of CaliforniaInventors: Atul Navinchandra Parikh, Chanel Kitmon Yee, Meri Lynn Amweg
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Patent number: 7090888Abstract: A method of making an ophthalmological implant by applying a layer of pharmaceutical agent and an overlying layer of a bioerodible material, a biodegradable material, a bloavailable material or a mixture thereof, the overlying layer having variable thickness and being dimensioned for prolonged release of the pharmaceutical agent from the implant as the overlying layer degrades.Type: GrantFiled: January 17, 2003Date of Patent: August 15, 2006Inventors: Michael E. Snyder, Eric M. Dobrusin
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Process for the manufacture of interpenetrating polymer network sheeting and useful articles thereof
Patent number: 7087135Abstract: A novel method of producing interpenetrating polymer network (“IPN”) sheeting. Particularly, an improved method of producing such sheeting and bonding it to a backing layer for use as various types of wound dressings and scar management products. The new process represents several improvements over previous techniques as follows: a) single-pass process, b) no second coating of liquid polymer required to act as glue, c) no solvents or other processing aids required, d) no additional oven length needed to effect the required dwell time, e) increased line speed relative to prior techniques, and g) the carrier substrate 20 need only be coated with a release surface on one side.Type: GrantFiled: November 14, 2003Date of Patent: August 8, 2006Assignee: Bio Med Sciences, Inc.Inventor: Mark E. Dillon -
Patent number: 6955832Abstract: The present invention provides novels inks and methods for making a colored polymeric substrates, preferably a contact lens. In the inventive method at least a portion of a surface of a lens is coated with a color coat comprising at least one colorant, and a binder polymer obtained by copolymerizing a first monomer being ethylenically unsaturated and having a latent crosslinkable pendent group; and a second monomer having an ethylenically unsaturated double bond copolymerizable with the first monomer. The lens is then subjected to conditions that cause the color coat to adhere to the lens.Type: GrantFiled: March 15, 2002Date of Patent: October 18, 2005Assignee: Novartis AGInventors: Michael Hugh Quinn, Robert Carey Tucker, Sandra Corti, John Christopher Phelan
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Patent number: 6953602Abstract: The invention relates to a adhesive article comprising at least one backing layer with a first and second surface and a pressure sensitive adhesive layer adhered first surface of the backing layer in a pattern, wherein the pattern of the adhesive layer has an adhesive free area of less than about 25% and wherein the adhesive article has a water vapor transmission rate of greater than about 2000 g/m2/24 hour. The invention also relates to a method of forming an adhesive article comprising (a) providing a release liner, (b) applying pressure sensitive adhesive in a pattern wherein the free adhesive area is less than 25%, and (c) applying a backing layer to the pressure sensitive adhesive.Type: GrantFiled: October 15, 2002Date of Patent: October 11, 2005Assignee: Avery Dennison CorporationInventors: Theresa L. Carte, Kim Vesey, Omar Attia, Brett Ulrich, Karen L. Spilizewski, Robert Li-Jiun Sun
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Patent number: 6951463Abstract: The first embodiment of present invention provides a composition, which includes: (a) a photocatalytic titanium oxide or a photocatalytic titanium oxide precursor; (b) at least one selected from the group including: a silicon compound having the following formula (I): wherein X1, X2, X3 and X4 each independently represent an alkoxy group or a halogen atom, a hydrolyzate of the silicon compound (I), a silicone resin, silicone resin precursor and silica; and (c) a liquid medium. Another embodiment of the present invention provides a dental and oralogic composition, that includes a photocatalytic titanium oxide or a photocatalytic titanium oxide precursor. Another embodiment of the present invention provides a dental and oralogic composition, that includes a photocatalytic titanium oxide or a photocatalytic titanium oxide precursor, and a liquid medium.Type: GrantFiled: December 4, 2000Date of Patent: October 4, 2005Assignee: Kuraray Co., Ltd.Inventors: Eiichi Masuhara, Yoshinori Kadoma, Junichi Yamauchi, Koichi Okada, Satoshi Yamaguchi
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Patent number: 6943204Abstract: A process for forming a surface modification on a polymer substrate and polymer substrates having such surface modifications. The process comprises the steps of absorbing a swelling monomer into the polymer substrate for a period of time in order to swell the polymer substrate; removing the swollen polymer from the swelling monomer; transferring the swollen polymer to a reaction mixture containing at least one functional monomer; polymerizing the functional monomer in the reaction mixture containing the swollen polymer substrate for a period of time; and removing the polymer from the reaction mixture. Because the surface modification produced by the process is a surface interpenetrating polymer network, the process is not sensitive to the reactive groups located on the surface of the polymer substrate. Further, the surface interpenetrating network bonds to the polymer substrate through caternary connections or other forms of chain entanglement and this is quite stable.Type: GrantFiled: August 26, 2003Date of Patent: September 13, 2005Assignee: Advanced Medical Optics Uppsala ABInventors: Yading Wang, Robert van Boxtel, Stephen Q. Zhou
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Patent number: 6936345Abstract: A process for antibacterially finishing a polymeric substrate involving: (a) providing a polymeric substrate made from a compound selected from the group consisting of a polyolefin, a polyester, and combinations thereof; (b) providing an antibacterial finish composition containing: (i) from about 0.1 to 10% by weight of at least one monoester of glycerol and a C6-14 fatty acid; and (ii) from about 0.01 to 10% by weight of chitosan, all weights being based on the weight of the composition; and (c) applying the composition onto the polymeric substrate.Type: GrantFiled: January 30, 2002Date of Patent: August 30, 2005Assignee: Cognis Deutschland GmbH & Co. KGInventors: Christine Wild, Raymond Mathis, Edda Schirmer, Rolf Stein
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Patent number: 6929819Abstract: A toilet training article in the form of a toilet training pad containing an effervescent agent is disclosed. The toilet training pad, which may be an insertable pad or integrated directly into an undergarment, contains an effervescent agent which releases gas upon being contacted by urine. The effervescent agent may be in the form of a compound containing a substantially inert gas, or may be a combination of compounds that, upon being contacted by urine, produce a gas.Type: GrantFiled: March 6, 2003Date of Patent: August 16, 2005Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Richard L. Underhill, Marsha M. Malone, Bernard J. Minerath, III, Beth A. Lange, Duane G. Krzysik, David W. Koenig, Kimberly M. Bleck
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Patent number: 6926919Abstract: Methods for fabricating coatings for implantable medical devices are disclosed. The coatings include blends of hydrophilic and hydrophobic polymers. The methods provide for treatment of the coatings to cause enrichment a region close to the outer surface of the coating with the hydrophilic polymers.Type: GrantFiled: February 26, 2003Date of Patent: August 9, 2005Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Stephen D. Pacetti
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Patent number: 6919100Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism or to treat a particular condition. A dip coating process is utilized to minimize waste. An aqueous latex polymeric emulsion is utilized to coat any medical device to a desired thickness by allowing for successive dipping and drying cycles. In addition, aqueous latex polymeric emulsions pose less of a chance of the bridging phenomenon associated with organic solvent based polymers.Type: GrantFiled: January 22, 2003Date of Patent: July 19, 2005Assignee: Cordis CorporationInventor: Pallassana V. Narayanan
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Patent number: 6911228Abstract: A process for manufacturing a toilet training article in the form of a toilet training pad containing an astringent agent or source thereof is disclosed. The toilet training pad, which may be an insertable pad or integrated directly into an undergarment, contains an astringent agent or source thereof which does not contact the wearer's skin until urination occurs at which time a tingling or other sensation is felt on the skin. To prevent contact of the astringent agent with the wearer's skin until urination, the astringent agent may be microencapsulated into a dissolvable shell or may be inserted into a microsponge.Type: GrantFiled: June 6, 2003Date of Patent: June 28, 2005Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Richard L. Underhill, Marsha M. Malone, Bernard J. Minerath, III, Beth A. Lange, Duane G. Krzysik, David W. Koenig
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Patent number: 6905724Abstract: The present invention relates to a process for derivatizing supports on a carriers, wherein a functional group is activated on a support surface by reaction with an activating reagent and then reacted with an amine component. The invention also relates to a support with a dendrimer structure on its surface and to the use of a support that has been produced according to the invention for binding biopolymers.Type: GrantFiled: November 17, 1999Date of Patent: June 14, 2005Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen RechtsInventor: Markus Beier
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Patent number: 6899914Abstract: A method of applying a marker element (6; 6?; 6?; 25; 25?; 26; 28) to an implant (1; 1?; 1?; 1??; 20; 20?), in particular a stent, intended for implantation in the human or animal body, comprising a main body and an opening (3; 3?; 3?; 3??; 21; 21?) provided in said main body (2; 2?; 2?; 2??; 22; 22?) for receiving the marker element (6; 6?; 6?; 25; 25?; 26; 28), wherein to form at least a part of the marker element (6; 6?; 6?; 25; 25?; 26; 28) a hardenable material or material mix is introduced into the opening and hardened therein.Type: GrantFiled: December 13, 2001Date of Patent: May 31, 2005Assignee: Biotronik Mess-und Therapiegeraete GmbH Ingeniurbuero BerlinInventors: Max Schaldach, Jr., Klaus-Peter Schmitz, Jens Gobrecht, Alexander Rzany, Detlef Behrend, Max Schaldach
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Patent number: 6896926Abstract: The present invention provides an improved LbL-coating process for modifying the surface of a medical device, preferably an ophthalmic device, more preferably a contact lens. An LbL coating on a contact lens, which is prepared according to the process of the invention, can have increased hydrophilicity characterized by an averaged contact angle of about 80 degree or less, preferably about 50 degrees or less, while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material.Type: GrantFiled: September 3, 2003Date of Patent: May 24, 2005Assignee: Novartis AGInventors: Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Yasuo Matsuzawa
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Patent number: 6881434Abstract: A process for improving the knot tensile strength of a braided suture while maintaining its first throw holding characteristics includes the steps of applying a biocompatible co-polymer to the braided suture and then heating the suture to a temperature above the flow point of the co-polymer. An outer coat is applied to the suture after the heating step. The suture may be scoured with a solvent before the co-polymer is applied or the co-polymer may be applied simultaneously with the scouring step. The co-polymer preferably comprises one or more lactones, more preferably, ?-caprolactone and glycolide. This process may be used with bioabsorbable sutures, such as those comprising filaments made of polyglycolide and polylactide.Type: GrantFiled: July 31, 2002Date of Patent: April 19, 2005Assignee: Ethicon, Inc.Inventors: Henry Pokropinski, Jr., Howard Scalzo, Jerome A Fischer
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Patent number: 6861087Abstract: A method for modifying surface of biodegradable porous polymer scaffold for tissue engineering using a low temperature plasma discharge apparatus, and particularly, a method for inducing the biodegradable porous polymer scaffold to be hydrophilic by graft polymerizing a hydrophilic monomer on the surface of the biodegradable porous polymer scaffold, which is made of polylactic acid, polyglycolic acid or poly(lactic acid-glycolic acid) copolymer, using a low temperature plasma. The surface-modified porous polymer scaffold according to the present invention has an enhanced cell compatibility in cell culture in vitro, and promote tissue growth when the cell is transplanted into a body.Type: GrantFiled: October 16, 2002Date of Patent: March 1, 2005Assignees: Korea Institute of Science and Technology, Solco Biomedical Co., Ltd.Inventors: Dong Keun Han, Kwang Duk Ahn, Young Min Ju, Saeyoung Ahn