Mixed Culture Patents (Class 435/252.4)
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Publication number: 20130045291Abstract: It is to provide a composition derived from lactic acid bacteria having an anti-allergic effect (an effect of suppressing allergic symptoms such as hay fever) synergistically, and a food product, pet food, etc. containing the composition. It is to prepare a composition having an anti-allergic action, containing Lactobacillus crispatus KT-11 strain, KT-23 strain, or KT-25 strain bacterial cells and viable bacteria, dead bacteria, or a processed product of bacterial cells of other lactic acid bacteria belonging to the genus Lactobacillus, genus Bifidobacterium, genus Leuconostoc, genus Enterococcus, genus Pediococcus, etc. at a biomass-converted ratio of 99:1 to 50:50, preferably 99:1 to 75:25.Type: ApplicationFiled: March 4, 2011Publication date: February 21, 2013Applicant: KITII CO., LTD.Inventors: Keisuke Tobita, Hajime Otani
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Patent number: 8377430Abstract: The invention relates to an infant formula comprising a source of protein in an amount of not more than 2.0 g/100 kcal, a source of lipids, a source of carbohydrate and a probiotic wherein the probiotic is present in an amount equivalent to between 102 and 105 cfu/g of dry formula. The invention further extends to the use of such an infant formula to modulate the immune system of a neonatal infant to promote the development in the first few weeks of the life of the infant of a beneficial intestinal microbiota comparable with that found in breast fed babies as well as to promote the maturation of the immune system of a neonatal infant in the first few weeks of life.Type: GrantFiled: April 10, 2006Date of Patent: February 19, 2013Assignee: Nestec S.A.Inventors: Anne Donnet-Hughes, Eduardo Schiffrin, Ferdinand Haschke, Marie-Claire Fichot, Karl-Josef Huber-Haag
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Publication number: 20130022575Abstract: The invention relates to one or more systems and methods for creating a mixture of cultures used to replace intestinal flora. Specifically, the invention relates to methods and systems of treating diseases including Clostridium difficile and Crohn's disease by introducing a mixture of pure cultures of viable bacteria into the gastrointestinal tract.Type: ApplicationFiled: July 19, 2011Publication date: January 24, 2013Applicant: MICROBIAL RXInventor: Timothy Cassity
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Patent number: 8357526Abstract: The present disclosure relates to isolation and identification of unique Pseudomonas stutzeri strains that can grow on crude oil under denitrifying conditions and are useful in oil recovery.Type: GrantFiled: April 18, 2008Date of Patent: January 22, 2013Assignee: E.I. du Pont de Nemours and CompanyInventors: Sharon Jo Keeler, Robert D. Fallon, Edwin R. Hendrickson, Linda L. Hnatow, Scott Christopher Jackson, Michael P. Perry
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Patent number: 8354265Abstract: The present invention concerns the field of bacterial biocontrol. More precisely, the invention relates to the identification of chemicals which promote the growth of bacteria inactivating NAHL, such as gamma-caprolactone (GCL) and 4-heptanolide (HTN) and their use in soil additives.Type: GrantFiled: January 18, 2008Date of Patent: January 15, 2013Assignees: Centre National de la Recherche Scientifique, Comite Economique Agricole Production des Plants du Nord (Comite Nord Pomme de Terre)Inventors: Denis Faure, Amélie Cirou, Yves Dessaux
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Patent number: 8343749Abstract: Embodiments of the present invention preferably relate to a method and apparatus for a two-stage membrane-based production of gas, preferably hydrogen gas or the like, from solid biological materials, preferably organic waste materials or the like, comprising anaerobic hydrolysis and fermentation and photofermentation using microorganisms.Type: GrantFiled: January 10, 2012Date of Patent: January 1, 2013Assignee: Arrowhead Center, Inc.Inventors: Nagamany Nirmalakhandan, Shuguang Deng, Geoffrey Smith
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Publication number: 20120315668Abstract: Disclosed are novel microbial compositions and biodegradation processes to treat marine animal or marine animal by-products to produce solid, liquid and lipid fractions that contain useful compounds.Type: ApplicationFiled: June 25, 2012Publication date: December 13, 2012Applicant: Agrinos ASInventors: Jaime López-Cervantes, Dalia Isabel Sánchez-Machado, Karl Reiner Fick Rochin
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Publication number: 20120295818Abstract: A culturing method includes culturing a sample having one or more species of target pathogens of a detection assay and competing microorganisms under oxygen-poor condition in a growth medium. The growth medium can be a non-selective medium. The oxygen-poor condition is effective to prevent competing microorganisms from suppressing growth of the target pathogens. This method can be used in combination with a sample preparation method for large volume particulate samples using highly porous filter material and porous spherical filter aid.Type: ApplicationFiled: January 24, 2011Publication date: November 22, 2012Applicants: HITACHI CHEMICAL RESEARCH CENTER, INC., HITACHI CHEMICAL CO., LTD.Inventor: Taku Murakami
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Publication number: 20120288586Abstract: Methods and compositions for producing cheese with S. thermophilus and a urease inhibitor, and for producing hard or semi-hard cheese, such as cheddar, with S. thermophilus that is partially or completely deficient in its ability to release ammonia from urea are provided. Methods and compositions for reducing the amount of open texture (e.g., slits, cracks, or fractures) in hard and semi-hard cheeses, as well as hard and semi-hard cheeses that comprise one or more S. thermophilus bacteria that are partially or completely deficient in their ability to release ammonia from urea, are also provided.Type: ApplicationFiled: April 20, 2012Publication date: November 15, 2012Inventor: Lars W. Peterson
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Patent number: 8309073Abstract: The invention relates to a probiotic combination comprising different combinations of lactobacilli, propionic acid bacteria and/or bifidobacteria. The probiotics are preferably combined with a suitable prebiotic to form a synbiotic. The combination of the invention can be consumed as such or combined with a suitable foodstuff or pharmaceutical product, and it is therapeutically useful for example for stimulating the immune system and for general health improvement.Type: GrantFiled: January 17, 2002Date of Patent: November 13, 2012Assignee: Valio Ltd.Inventors: Annika Mäyrä-Mäkinen, Tarja Suomalainen, Outi Vaarala
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Patent number: 8304226Abstract: Disclosed are quick dissolve tablets, each including freeze dried lysate of Lactobacillus reuteri, Lactobacillus casei, Lactobacillus plantarum, Llactobacillus rhamnosus GG, Lactobacillus acidophilus, Bifidobacterium bifidium, Bifidobacterium longum, Bifidobacterium infantis or Bifidobacterium breve and N-acetyl-glucosamine (NAG), as well as excipients, for oral mucosal administration, for improving the quality of life of Hepatitis C patients. Any formulation suitable for oral mucosal administration can be employed for administering the active ingredients in a sufficient dosage for therapeutic effect, one such formulation being: four parts of bacterial lysate and one part of N-acetyl D-glucosamine. Excipients can include one or more of, maltodextrin; xanthan gum; acesulfam K; lemon powder and a flavoring, e.g., juice; Mannitol TL-32-04, Microcrystalline Cellulose and Carrageenan, Fructose, PVP-XL TL-11-04, Gellan Gum, Citrus TL 1-04, Orange TL 19-04, Sucrolose TL-13-04, and Mg ST TL-13-04.Type: GrantFiled: April 18, 2012Date of Patent: November 6, 2012Inventor: Carl Miller
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Publication number: 20120258506Abstract: Disclosed is a process in which a recombinant organism, such as a yeast, expressing a heterologous S-adenosylmethionme (SAM)-dependent methyl halide transferase (MHT) protein is combined with a halide and a carbon source in a cultivation medium under conditions in which methyl formate is produced. The cell may genetically modified to express methyl formate synthase, methanol dehydrogenase and/or hydrolytic dehalogenase at levels higher than a cell of the same species that is not genetically modified. The methyl formate may be collected and used in a variety of applications. The halide may be chlorine, bromine or iodine.Type: ApplicationFiled: July 22, 2010Publication date: October 11, 2012Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Christopher A. Voigt, Travis S. Bayer
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Publication number: 20120252100Abstract: The present invention relates to a mixed strain culture for the disposal of food waste, and more particularly, to a mixed strain culture for the disposal of food waste which has high degradation activity on cellulose, amylose, protein, and fat at a wide range of temperatures, pH levels, and salinities, and which can degrade food waste having a high moisture content and therefore can degrade food waste in an efficient manner. The present invention also relates to a food waste disposal method using the mixed strain culture.Type: ApplicationFiled: December 23, 2010Publication date: October 4, 2012Inventors: You Jung Jung, Tae Seok Ahn, Da Woon Jung, Ahn Na Cho, Eun Young Lee, Myoung Sun Lee
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Patent number: 8278246Abstract: Bacterial compositions effective for inhibiting fungal diseases of potatoes and/or potato sprouting are produced by co-culture of two or more of Pseudomonas fluorescens (NRRL B-21133), Pseudomonas fluorescens biovar (NRRL B-21053), Pseudomonas fluorescens (NRRL B-21102) and Enterobacter cloacae (NRRL B-21050). Compositions produced by co-culture of these bacteria together in the same culture medium are significantly more effective for inhibiting fungi-induced diseases of potatoes and/or inhibiting sprouting of potatoes, than blends or mixtures of the same bacteria cultured separately.Type: GrantFiled: September 29, 2009Date of Patent: October 2, 2012Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Patricia J. Slininger, David A. Schisler
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Publication number: 20120225042Abstract: The present invention relates to compositions, including live organisms, nucleic acid and amino acid sequences, constructs and cells comprising these, which are used to competitively exclude pathogenic organisms from the alimentary canals of vertebrates to achieve prophylaxis or therapeutic effects.Type: ApplicationFiled: August 25, 2010Publication date: September 6, 2012Applicant: Plant Bioscience LimitedInventors: Arjan Narbad, Nicola Horn, Andrew Lee, Claire Shearman, Udo Wegmann
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Patent number: 8257693Abstract: The present invention provides a composition comprising prebiotic and probiotic components and is used to reduce elevated levels of nitrogenous waste products and to promote a healthy bowel microenvironment.Type: GrantFiled: March 19, 2009Date of Patent: September 4, 2012Assignee: Kibow Biotech, Inc.Inventor: Natarajan Ranganathan
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Patent number: 8227235Abstract: Disclosed herein are compositions for the treatment of a disease in an animal including yeast extract of Saccharomyces cerevisiae, Bacillus licheniformis or Bacillus subtilis spores, and a carrier. Also included are animal feed compositions including the composition for the prevention, control and/or treatment of a disease in an animal and an animal's food/feed. The compositions are useful to prevent, control, and treat diseases such as necrotic enteritis in poultry when used in combination with an anticoccidal ionophore or coccidiosis vaccine.Type: GrantFiled: September 21, 2009Date of Patent: July 24, 2012Assignee: Alpharma, LLCInventors: James Skinner, Doug Rupp
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Publication number: 20120178147Abstract: The invention relates to a consortium of microorganisms that can be used to dehalogenate a chemical composition. Methods of use of the same for biomass production and for use of the same in bioremediation are described.Type: ApplicationFiled: July 23, 2010Publication date: July 12, 2012Applicant: Arizona Board of Regents for and on behalf of Arizona State UniversityInventors: Rosa Krajmalnik-Brown, Rolf U. Halden, Anca G. Delgado, Michal Ziv-El
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Patent number: 8192733Abstract: A probiotic composition including the bacilli (1) Bacillus subtilis, (2) Bacillus coagulans, and (3) Enterococcus faecium. The composition may further include a carrier medium, such as fructo-oligo-saccharides (FOS), as incorporated in a dose form such as a pill, capsule, powder or sachet. The compositions of the disclosure may be usefully employed as health or nutritional supplements, food additives, or therapeutic agents for combating a wide variety of physiological disorders, such as irritable bowel syndrome, autism, and fibromyalgia.Type: GrantFiled: July 20, 2010Date of Patent: June 5, 2012Assignee: Cobb & AssociatesInventors: Mark L. Cobb, Alyson Cobb
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Publication number: 20120100589Abstract: A method for treatment of a material comprising lignocellulosic fibres is disclosed. More particularly, the treatment increases the accessibility of the lignocellulosic fibres for following microbial or biological processes.Type: ApplicationFiled: March 8, 2010Publication date: April 26, 2012Applicants: XERGI A/S, NOVOZYMES A/SInventors: Danielle Rhine, Anders Peter Jensen, Stefan Borre-Gude
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Patent number: 8163526Abstract: A method for increasing production of ethanol in an ethanologenic cell using an autoinducer molecule, for example, AI-2.Type: GrantFiled: October 17, 2007Date of Patent: April 24, 2012Assignee: The University of DurhamInventors: Adrian Robert Walmsley, Maria Ines Borges-Walmsley, Jung Woo Yang
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Patent number: 8148138Abstract: A seed treated with a fungal/bacterial antagonist combination and a seed assembly comprising a seed and a fungal/bacterial antagonist combination. The fungal/bacterial antagonist combination comprises a Trichoderma virens fungal antagonist and a Bacillus amyloliquefaciens bacterial antagonist for controlling plant pathogens as a biocontrol agent, bio-pesticide or bio-fungicide. In preferred embodiments, the invention produces an increase in plant yield. Control of early and late season stalk and root rot caused by fungi such as Fusarium, Phythium, Phytophthora and Penicillium in tomatoes, peppers, turf grass, soybeans, sunflower, wheat and corn is achieved.Type: GrantFiled: August 16, 2008Date of Patent: April 3, 2012Inventor: Thomas D. Johnson
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Publication number: 20120064605Abstract: A microbial composition for concurrent dechlorination of a mixture of chlorinated ethanes and chlorinated ethenes includes a isolated consortium of bioremediative microorganisms comprising strains of microorganism comprising Clostridium, Acetobacterium, Dehalobacter, Bacteroides, and Proteobacteria. The composition may also include Methanomicrobia.Type: ApplicationFiled: November 18, 2011Publication date: March 15, 2012Inventors: Michelle M. Lorah, Elizabeth A. Jones, Mary A. Voytek
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Patent number: 8124387Abstract: The invention relates to a process for the production of optically active Citronellal by enzymatic reduction of Citral with a reductase from Zymomonas mobilis.Type: GrantFiled: November 10, 2006Date of Patent: February 28, 2012Assignee: BASF SEInventors: Rainer Stuermer, Thomas Friedrich, Andre Mueller, Bernhard Hauer, Bettina Rosche
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Publication number: 20120045427Abstract: The present invention relates to the antagonistic bacteria that are used to prevent and eliminate tobacco bacterial wilt and their microbial organic fertilizer, which belong to the technology for agricultural intensive production. The present invention separates two antagonistic bacteria (Brevibacillus brevis NJL-25 and Bacillus cereus NJL-14) that have remarkable antagonistic action against the pathogens of tobacco bacterial wilt. Microbial organic fertilizer is produced from these antagonistic bacteria and organic compost. Wherein, the content of each of NJL-25 and NJL-14 is above 1×1010 cfu/g, the content of total nitrogen is 4˜5% (above 90% of the nitrogen is organic nitrogen), the content of total nitrogen-phosphorus-kalium nutrient is 6˜10% and the content of organic matter is 30˜35%. As indicated by experiments, after the microbial organic fertilizer is applied into soil, it will enable rapid multiplication of the antagonistic bacteria into a dominant microflora in the soil and achieve more than 97.Type: ApplicationFiled: November 17, 2009Publication date: February 23, 2012Applicants: Jiangsu New Ground Bio-Fertilizer Engineering Center Co., Ltd., Nanjing Agricultural UniversityInventors: Qirong Shen, Yanxia Liu, Xingming Yang, Yangchun Xu, Biao Shen
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Patent number: 8114292Abstract: The invention concerns a novel isolated microorganism characterized in that it is capable of: i) transforming Kjeldahl nitrogen, ammonia nitrogen and/or nitrogen oxides into gas nitrogen; and ii) transforming carbonaceous matter into carbon dioxide; both transformation processes being carried out in aerobic condition. The invention also concerns a method for treating wastewater using said microorganism.Type: GrantFiled: April 20, 2007Date of Patent: February 14, 2012Assignee: Eco SolutionInventor: Alexandre Da Costa
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Patent number: 8114657Abstract: Several bacterial species were isolated from marine segment obtained from seabed sediment at depths exceeding 1700 feet. At least four of the bacteria produced a compound that showed antibacterial activity against one or more multiple-drug-resistant (MDR) bacteria isolated from hospitals and clinics. One isolate, SJCH-12, exhibited a broad range of activity against MDR strains tested, including methicillin resistant Staphylococcus aureus (MRSA).Type: GrantFiled: August 24, 2009Date of Patent: February 14, 2012Assignee: St. Joseph' Children' HospitalInventors: Michael Lawman, Selena Braccili, Shabnam Eidizadeh
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Patent number: 8114669Abstract: A method for determining the effect of a plurality of culture conditions on a cell, comprising the steps of: a) providing a first set of groups of cell units each comprising one or more cells, and exposing said groups to desired culture conditions; (b) pooling two or more of said groups to form at least one second pool; (c) subdividing the second pool to create a further set of groups of cell units; (d) exposing said further groups to desired culture conditions; (e) optionally, repeating steps (b)-(d) iteratively as required; and (f) optionally assessing the effect on a given cell unit of the culture conditions to which it has been exposed.Type: GrantFiled: October 3, 2003Date of Patent: February 14, 2012Assignee: Plasticell LimitedInventor: Yen Choo
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Patent number: 8101170Abstract: The invention relates to a probiotic health or fitness promoting human or animal foodstuff and/or drinking water additive, comprising a mixture of microorganisms, selected from the group Enterococcus faecium, DSM 16211, Lactobacillus reuteri, DSM 16350, Lactobacillus salivarius ssp. salivarius, DSM 16351, Pediococcus acidilactici, DSM 16210, Bifidobacterium animalis and DSM 16284. The invention further relates to a use of the human or animal foodstuff and/or drinking water additive, in particular for prevention of the harmful effect of a number of undesirable germs in the digestive system of animals and/or domestic birds.Type: GrantFiled: June 14, 2006Date of Patent: January 24, 2012Assignee: Erber AktiengesellschaftInventors: Regina Plail, Gerd Schatzmayr, Eva Maria Binder, Michaela Mohnl, Alfred Klimitsch, Sabine Nitsch, Viviana Klose
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Publication number: 20120015806Abstract: The present invention relates to eco-friendly compositions and methods for providing plant growth enhancing formulations comprising mixtures of microbial isolates. The microbial consortium is developed for customized solution of soil health related problem such as with plant growth promoting properties including root and shoot length elongation, early and high germination rate, high yield, decrease in soil pathogenic load and increase soil micro and macronutrient status. These specifically designed polymicrobial formulations would further provide protection against plant pathogens lowering the need for nitrogen containing fertilizers, solubilize minerals, protect plants against pathogens, and make available to the plant valuable nutrients, such as phosphate, thus reducing and eliminating the need for using chemical fertilizers and chemical pesticides.Type: ApplicationFiled: March 25, 2010Publication date: January 19, 2012Inventors: Sitaram Prasad Paikray, Vedpal Singh Malik
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Patent number: 8097245Abstract: The disclosure relates to a solid glass matrix of polysaccharide, saccharides and polyols as delivery vehicle for preservation and post gastric administration of a probiotic. The delivery vehicle is capable of releasing the probiotic at their site of action. The present invention further includes methods of making and using the solid glass matrix delivery vehicle of the invention.Type: GrantFiled: December 28, 2006Date of Patent: January 17, 2012Assignee: Advanced Bionutrition CorporationInventors: Mordechi Harel, Keren Kohavi-Beck
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Patent number: 8075928Abstract: For the purpose of providing a method of safely and inexpensively producing a fermented plant extract containing an immunopotentiator at a high concentration, the method for fermentation and culture of the present invention ferments a plant component such as wheat flour using Pantoea agglomerans which is a gram negative bacterium which lives in a symbiotic relationship with a plant such as wheat and apple. It becomes possible to remarkably augment an immunopotentiation action which the plant has. In addition, these are not contaminated with impurities derived from animal components, and thus these are highly safe.Type: GrantFiled: September 22, 2004Date of Patent: December 13, 2011Assignees: BioMedical Research Group Inc.Inventors: Gen-Ichiro Soma, Chie Kohchi, Hiroyuki Inagawa, Takashi Nishizawa, Yukinori Takahashi
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Patent number: 8067223Abstract: An isolated microbial consortium is described that includes a first microbial consortium having Thermacetogenium phaeum to metabolize a complex hydrocarbon substrate into metabolic products comprising an acetate compound. The consortium also includes a second microbial consortium having a methanogen to convert the acetate compound into a final product that includes methane. Also, a method of increasing production of materials with enhanced hydrogen content. The method includes isolating Thermacetogenium phaeum from geologic formation water, culturing the isolated Thermacetogenium phaeum to increase the Thermacetogenium phaeum population, and introducing a consortium of the cultured Thermacetogenium phaeum, which may include spores of Thermacetogenium phaeum, into a hydrocarbon formation containing a complex hydrocarbon substrate.Type: GrantFiled: May 27, 2008Date of Patent: November 29, 2011Assignee: Luca Technologies, LLCInventors: Robert S. Pfeiffer, Glenn A. Ulrich, Gary Vanzin
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Publication number: 20110250676Abstract: The present invention is a kit and method for bioremediation of deicing fluids containing glycol. Using a combination Bacillus, Pseudomonas, yeast and filamentous fungi strains selected for the ability to grow on high levels of glycol, bioremediation of airport runoff is provided.Type: ApplicationFiled: April 7, 2011Publication date: October 13, 2011Inventor: Raj J. Mehta
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Patent number: 8034605Abstract: Provided is microbial materials for degradation of oils and toxic chemicals. The microbial material comprises (a) a microorganism and culture filtrate capable of degrading oil and toxic chemicals being at least one selected from the group consisting of Trichosporon loubieri Y1-A of deposit No. KCTC 10876BP, Trichosporon cutaneum, and white-rot fungi living upon the surface of wood, (b) rapeseed oils for producing more sophorolipid in surface of the said microorganism, (c) lipophilic powder being at least one selected from the group consisting of natural wax, synthetic wax, beeswax and waste candle, and (d) a microbial nutrient. This invention further comprises (e) the Bacillus subtilis of Deposit No. KCCM 10639 and the Bacillus subtilis of Deposit No. KCCM 10640. The microbial material can efficiently, rapidly degrade contaminants that are unreadily degradable, by increasing a contact area with the microorganism capable of degrading the unreadily degradable contaminants.Type: GrantFiled: July 17, 2007Date of Patent: October 11, 2011Assignee: Kyu-Jin YumInventor: Kyu-Jin Yum
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Patent number: 8025874Abstract: A composition is provided that includes Bacillus subtilis 2084 (NRRL B-50013) or a strain having all of the identifying characteristics of the Bacillus subtilis 2084 (NRRL B-50013), B. subtilis 27 (NRRL B-50105) or a strain having all of the identifying characteristics of the B. subtilis 27 (NRRL B-50105), and B. licheniformis 21 (NRRL B-50134) or a strain having all of the identifying characteristics of the B. licheniformis 21 (NRRL B-50134). Animal bedding that includes the Bacillus strains is also provided, as well as a method of making the animal bedding. Also provided are methods of controlling odors from animal waste. A method of making a composition including the Bacillus strains is also provided.Type: GrantFiled: April 17, 2009Date of Patent: September 27, 2011Assignee: Danisco A/SInventors: Marianne Cain Bellot, Keith J. Mertz, Thomas G. Rehberger
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Publication number: 20110200709Abstract: The present invention relates to a method for the preparation of a fermented milk product comprising Bifidobacteria in combination with lactic acid bacteria of the species Lactococcus lactis, Sterptococcus thermophilus, and/or Lactobacillus bulgaricus. The problem to be solved is to provide a method to improve growth of Bifidobacteria population in milk during the fermentation process for making fermented milk products (e.g. a yogurt) in order to obtain a high cell count of Bifidobacteria in the final product.Type: ApplicationFiled: August 28, 2009Publication date: August 18, 2011Inventors: Ditte Marie Folkenberg, Cecile Seimandi
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Patent number: 7993905Abstract: The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic islands that adhere cells, isolated by cytophobic regions to which cells do not adhere, contiguous with the cytophilic islands. The islands or the regions or both may be formed of a self-assembled monolayer (SAM).Type: GrantFiled: July 1, 2008Date of Patent: August 9, 2011Assignees: President and Fellows of Harvard College, Massachusetts Institute of Technology, Children's Medical Center CorporationInventors: Rahul Singhvi, Amit Kumar, George M. Whitesides, Donald E. Ingber, Gabriel P. Lopez, Daniel I. C. Wang, Gregory Stephanopoulos
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Publication number: 20110165618Abstract: The invention relates to systems and methods for production of compounds by yeast and other organisms. In one approach yeast engineered for production of a compound of commercial value is cultured together with a cellulosic bacteria, and the yeast uses a metabolic product produced by the bacteria as a carbon source. Methyl halides are an example of compounds that may be produced by this process. The invention also relates to production of organic compounds using genetically engineered organisms expressing a S-adenosylmethionine (SAM)-dependent methyl halide transferase. In one approach the organism, halides and a carbon source are incubated in a cultivation medium under conditions in which methyl halide is produced. The methyl halide may be collected and converted into non-halogenated organic molecules.Type: ApplicationFiled: November 26, 2008Publication date: July 7, 2011Inventors: Christopher A. Voigt, Travis S. Bayer
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Publication number: 20110160124Abstract: Several bacterial species were isolated from marine segment obtained from seabed sediment at depths exceeding 1700 feet. At least four of the bacteria produced a compound that showed antibacterial activity against one or more multiple-drug-resistant (MDR) bacteria isolated from hospitals and clinics. One isolate, SJCH-12, exhibited a broad range of activity against MDR strains tested, including methicillin resistant Staphylococcus aureus (MRSA).Type: ApplicationFiled: August 24, 2009Publication date: June 30, 2011Applicant: St. Joseph's Children's HospitalInventors: Michael Lawman, Selena Braccili, Shabnam Eidizadeh
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Publication number: 20110151508Abstract: Disclosed are novel microbial compositions and biodegradation processes to treat marine animal or marine animal by-products to produce solid, liquid and lipid fractions that contain useful compounds.Type: ApplicationFiled: December 21, 2010Publication date: June 23, 2011Applicant: Agrinos ASInventors: Jaime López-Cervantes, Dalia Isabel Sánchez-Machado, Karl Reiner Fick Rochin
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Publication number: 20110124089Abstract: A method to grow and concentrate algae by adding a bacterium to an aqueous algal solution. After the bacteria are added, the algae and bacterial precipitate out of solution and produce a viable algal concentration that is 30 to 45 percent algae by wet weight.Type: ApplicationFiled: November 19, 2010Publication date: May 26, 2011Inventors: Gary Scott Stepenoff, Karin L. Hastings
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Patent number: 7947440Abstract: The present invention provides a method for measuring the specific rate of ribosome synthesis for a distinct cell population, such as a distinct microbial population. For an actively growing (or non-growing) culture, the specific rate of ribosome synthesis is identical to the specific growth rate of the culture. With the method of the invention, researchers will be able to measure the specific growth rate of distinct cell populations in mixed cultures, such as biological reactor systems or environmental samples. In addition, the method of the invention provides the ability to identify members of a distinct cell population that are rapidly growing.Type: GrantFiled: September 15, 2006Date of Patent: May 24, 2011Assignee: University of South FloridaInventors: Peter George Stroot, Matthew Raymond Cutter
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Patent number: 7935360Abstract: The invention concerns the application of compositions of micro-organisms in biological control of vine cryptogamic diseases. Said composition comprises a mixture of at least one bacterium and at least one yeast, the bacterium or bacteria and the yeast(s) being non-toxic for the plant. The invention also concerns bacterial and yeast strains, as well as biofungicide formulations containing an efficient amount of at least one composition of micro-organisms including in mixture at least one bacterium and one yeast, the bacterium or bacteria and the yeast(s) being non-toxic for the plant, and a composition of filamentous fungi, in particular of the genus Pichia, Pythium, Trichoderma, Gliocladium, Ampelomyces, Talaromyces, Epicococcum, combined with an inert carrier. The invention is useful for treating cryptogamic plant diseases, in particular crop plants and vine.Type: GrantFiled: July 1, 2003Date of Patent: May 3, 2011Assignee: Universite de BourgogneInventor: Bernard Paul
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Patent number: 7931892Abstract: The invention provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oralis strains and/or one or more isolated S. uberis strains. Compositions of the invention are useful to maintain oral health, by for example treating and/or preventing one or more symptoms of dental caries, periodontitis and/or other oral cavity diseases or wounds.Type: GrantFiled: August 10, 2004Date of Patent: April 26, 2011Assignee: Oragenics, Inc.Inventor: Jeffrey D. Hillman
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Publication number: 20110077158Abstract: Bacterial compositions effective for inhibiting fungal diseases of potatoes and/or potato sprouting are produced by co-culture of two or more of Pseudomonas fluorescens (NRRL B-21133), Pseudomonas fluorescens biovar (NRRL B-21053), Pseudomonas fluorescens (NRRL B-21102) and Enterobacter cloacae (NRRL B-21050). Compositions produced by co-culture of these bacteria together in the same culture medium are significantly more effective for inhibiting fungi-induced diseases of potatoes and/or inhibiting sprouting of potatoes, than blends or mixtures of the same bacteria cultured separately.Type: ApplicationFiled: September 29, 2009Publication date: March 31, 2011Inventors: Patricia J. Slininger, David A. Schisler
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Patent number: 7906131Abstract: The present invention provides formulations and methods for controlling or suppressing bacterial or fungal plant pathogens, including Erwina amylovora the bacteria that causes fire blight. A formulation for controlling of suppressing a plant pathogen may include at least one beneficial species of bacteria, at least one beneficial species of fungi, a nutrient, at least one compound that extends the length of time that the formulation remains effective. Typically the formulation is applied to the above ground structures of the plant including its leaves, flowers, stems, trunk, blossoms and fruit.Type: GrantFiled: January 12, 2007Date of Patent: March 15, 2011Inventor: William Brower
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Publication number: 20110053236Abstract: A method for increasing production of ethanol in an ethanologenic cell using an autoinducer molecule, for example AI-2.Type: ApplicationFiled: October 17, 2007Publication date: March 3, 2011Applicant: University of DurhamInventors: Adrian Robert Walmsley, Maria Ines Borges-Walmsley, Jung Woo Yang
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Patent number: 7883894Abstract: The present invention relates to a process for allowing homologous recombination between non-identical DNA sequences of an organism and various applications thereof.Type: GrantFiled: December 19, 2002Date of Patent: February 8, 2011Assignee: Mixis France S.A.Inventors: Ivan Matic, Miroslav Radman
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Patent number: 7871792Abstract: An isolated microbial consortium is described that includes a first microbial consortium having Thermacetogenium phaeum to metabolize a complex hydrocarbon substrate into metabolic products comprising an acetate compound. The consortium also includes a second microbial consortium having a methanogen to convert the acetate compound into a final product that includes methane. Also, a method of increasing production of materials with enhanced hydrogen content. The method includes isolating Thermacetogenium phaeum from geologic formation water, culturing the isolated Thermacetogenium phaeum to increase the Thermacetogenium phaeum population, and introducing a consortium of the cultured Thermacetogenium phaeum, which may include spores of Thermacetogenium phaeum, into a hydrocarbon formation containing a complex hydrocarbon substrate.Type: GrantFiled: May 27, 2008Date of Patent: January 18, 2011Assignee: LUCA Technologies, Inc.Inventors: Robert S. Pfeiffer, Glenn A. Ulrich, Gary Vanzin